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Tajiri Yudai  田尻 祐大

ORCIDConnect your ORCID iD *help
Researcher Number 30820659
Other IDs
Affiliation (Current) 2025: 九州大学, 歯学研究院, 共同研究員
2025: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 歯科・口腔外科
2025: 独立行政法人国立病院機構福岡東医療センター(臨床研究部), 独立行政法人国立病院機構福岡東医療センター臨床研究部, 医師
Affiliation (based on the past Project Information) *help 2022 – 2024: 九州大学, 歯学研究院, 共同研究員
2021: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 歯科・口腔外科 客員臨床研究員
2019 – 2020: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 歯科・口腔外科医師
Review Section/Research Field
Principal Investigator
Basic Section 57020:Oral pathobiological science-related
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related / Medium-sized Section 57:Oral science and related fields
Keywords
Principal Investigator
神経-癌連関 / TRPV4 / TRP / 扁平上皮癌 / MAPK / p63 / 口腔癌 / 腫瘍実質-間質連関
Except Principal Investigator
扁平上皮癌 / 耐性獲得 … More / BET阻害剤 / BETファミリー蛋白 / スーパーエンハンサー(SE) / 口腔扁平上皮癌(OSCC) / 細胞競合 / Field cancerization / 早期発見 / 口腔癌 / マウス腫瘍モデル / 臨床病理学的解析 / 癌微小環境 / Hippoシグナル / 扁平上皮がん / TRPV4 / TRPチャネル / 口腔がん Less
  • Research Projects

    (5 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (8 People)
  •  Elucidation of the molecular mechanism by which nerve-cancer connections promote neuroinvasion in salivary gland malignant tumorsPrincipal Investigator

    • Principal Investigator
      田尻 祐大
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Kyushu University
  •  Elucidation of the mechanism of resistance acquisition to super-enhancer-targeted anticancer therapies and novel strategies based on this mechanism

    • Principal Investigator
      清島 保
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Kyushu University
  •  Study of the instability among mutant epithelial cells, adjacent normal epithelial cells and stromal cells to develop strategies for screening and very early detection of cancer.

    • Principal Investigator
      清島 保
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kyushu University
  •  Elucidation of TRP signal activation mechanism in tumor-stromal seqence in oral tumor and its clinical applicationPrincipal Investigator

    • Principal Investigator
      Tajiri Yudai
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Kyushu University
  •  A new anti-cancer therapeutic strategy targeting the interrelation between tumorous mechanical extracellular microenvironment and novel oncogene-related gene signaling

    • Principal Investigator
      ozeki satoru
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      National Hospital Organization, Kyushu Medical Center (Clinical Institute)

All 2024 2023 2022 2020 2019

All Journal Article Presentation

  • [Journal Article] Wnt/β-catenin-C-kit axis may play a role in adenoid cystic carcinoma prognostication2024

    • Author(s)
      Fujii Shinsuke、Hasegawa Kana、Maehara Takashi、Kurppa Kari J.、Heikinheimo Kristiina、Warner Kristy A.、Maruyama Satoshi、Tajiri Yudai、Nor Jacques E.、Tanuma Jun-ichi、Kawano Shintaro、Kiyoshima Tamotsu
    • Journal Title

      Pathology - Research and Practice

      Volume: 254 Pages: 155148-155148

    • DOI

      10.1016/j.prp.2024.155148

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0262, KAKENHI-PROJECT-20K10096, KAKENHI-PROJECT-23K27792
  • [Journal Article] Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation.2023

    • Author(s)
      Alkhatib DZR, Thi Kim Truong T, Fujii S, Hasegawa K, Nagano R, Tajiri Y, Kiyoshima T.
    • Journal Title

      Pathol Res Pract.

      Volume: 246 Pages: 154493-154493

    • DOI

      10.1016/j.prp.2023.154493

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K10096, KAKENHI-PROJECT-21K09843, KAKENHI-PROJECT-22K17017, KAKENHI-PROJECT-23K27792
  • [Journal Article] The Semaphorin 3A-AKT axis-mediated cell proliferation in salivary gland morphogenesis and adenoid cystic carcinoma pathogenesis.2022

    • Author(s)
      Fujii S, Fujimoto T, Hasegawa K, Nagano R, Ishibashi T, Kurppa KJ, Mikami Y, Kokura M, Tajiri Y, Kibe T, Wada H, Wada N, Kishida S, Higuchi Y, Kiyoshima T.
    • Journal Title

      Pathol Res Pract.

      Volume: 236 Pages: 153991-153991

    • DOI

      10.1016/j.prp.2022.153991

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K10096, KAKENHI-PROJECT-21K09843, KAKENHI-PROJECT-19K19235, KAKENHI-PROJECT-22K17017, KAKENHI-PROJECT-20K09906, KAKENHI-PROJECT-20K10107
  • [Journal Article] The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation.2020

    • Author(s)
      Fujii S., Tajiri, Y., Hasegawa, K., Matsumoto,S., Yoshimoto, RU., Wada, H., Kishida, S., Kido, MA., Yoshikawa, H., Ozeki, S., Kiyoshima, T.
    • Journal Title

      Lab Invest.

      Volume: 100(2) Issue: 2 Pages: 311-323

    • DOI

      10.1038/s41374-019-0357-z

    • NAID

      120006938538

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11616, KAKENHI-PROJECT-19K10302, KAKENHI-PROJECT-18J11575, KAKENHI-PROJECT-19K18966
  • [Presentation] ヒト口腔扁平上皮癌に高発現した機械受容器TRPV4はCaMKII/AKTシグナル伝達を介して癌細胞の増殖を制御する2020

    • Author(s)
      田尻 祐大、藤井 慎介、清島 保
    • Organizer
      第62回 歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10302
  • [Presentation] 機械受容器TRPV4はヒト口腔扁平上皮癌細胞の増殖を制御する2020

    • Author(s)
      田尻 祐大、藤井 慎介、大関 悟、清島 保
    • Organizer
      第109回 日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-19K10302
  • [Presentation] TRPV4はヒト口腔扁平上皮癌細胞の増殖を制御する2020

    • Author(s)
      田尻 祐大、藤井 慎介、吉川 博政、清島 保
    • Organizer
      第65回 日本口腔外科学会総会・学術大会
    • Data Source
      KAKENHI-PROJECT-19K10302
  • [Presentation] TRPV4を介したカルシウム細胞内流入はCaMKII/AKTシグナル伝達を活性化し口腔扁平上皮癌細胞の増殖を促進する2020

    • Author(s)
      田尻 祐大、藤井 慎介、清島 保
    • Organizer
      第97回 九大病理研究会
    • Data Source
      KAKENHI-PROJECT-19K10302
  • [Presentation] 機械受容器TRPV4はヒト口腔癌細胞の増殖を制御する2019

    • Author(s)
      藤井慎介、田尻祐大、大関悟、清島保
    • Organizer
      第108回日本病理学会
    • Data Source
      KAKENHI-PROJECT-19K10302
  • 1.  清島 保 (20264054)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 2.  藤井 慎介 (60452786)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 3.  自見 英治郎 (40276598)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  長谷川 佳那 (30793989)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  ozeki satoru (80117077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  川野 真太郎 (00398067)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  和田 裕子 (70380706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  城戸 瑞穂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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