Tajiri Yudai 田尻祐大

Researcher Number	30820659
Other IDs
Affiliation (Current)	2025: 九州大学, 歯学研究院, 共同研究員 2025: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 歯科・口腔外科 2025: 独立行政法人国立病院機構福岡東医療センター(臨床研究部), 独立行政法人国立病院機構福岡東医療センター臨床研究部, 医師
Affiliation (based on the past Project Information) *help	2022 – 2024: 九州大学, 歯学研究院, 共同研究員 2021: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 歯科・口腔外科客員臨床研究員 2019 – 2020: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 歯科・口腔外科医師
Review Section/Research Field	Principal Investigator Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator 神経-癌連関 / TRPV4 / TRP / 扁平上皮癌 / MAPK / p63 / 口腔癌 / 腫瘍実質-間質連関 Except Principal Investigator 扁平上皮癌 / 耐性獲得 … More / BET阻害剤 / BETファミリー蛋白 / スーパーエンハンサー（SE） / 口腔扁平上皮癌（OSCC） / 細胞競合 / Field cancerization / 早期発見 / 口腔癌 / マウス腫瘍モデル / 臨床病理学的解析 / 癌微小環境 / Hippoシグナル / 扁平上皮がん / TRPV4 / TRPチャネル / 口腔がん Less

Elucidation of the molecular mechanism by which nerve-cancer connections promote neuroinvasion in salivary gland malignant tumorsPrincipal Investigator
- Principal Investigator
  
  田尻祐大
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Kyushu University
Elucidation of the mechanism of resistance acquisition to super-enhancer-targeted anticancer therapies and novel strategies based on this mechanism
- Principal Investigator
  
  清島保
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Kyushu University
Study of the instability among mutant epithelial cells, adjacent normal epithelial cells and stromal cells to develop strategies for screening and very early detection of cancer.
- Principal Investigator
  
  清島保
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kyushu University
Elucidation of TRP signal activation mechanism in tumor-stromal seqence in oral tumor and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  Tajiri Yudai
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Kyushu University
A new anti-cancer therapeutic strategy targeting the interrelation between tumorous mechanical extracellular microenvironment and novel oncogene-related gene signaling
- Principal Investigator
  
  ozeki satoru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  National Hospital Organization, Kyushu Medical Center (Clinical Institute)

All 2024 2023 2022 2020 2019

All Journal Article Presentation

[Journal Article] Wnt/β-catenin-C-kit axis may play a role in adenoid cystic carcinoma prognostication2024
- Author(s)
  Fujii Shinsuke、Hasegawa Kana、Maehara Takashi、Kurppa Kari J.、Heikinheimo Kristiina、Warner Kristy A.、Maruyama Satoshi、Tajiri Yudai、Nor Jacques E.、Tanuma Jun-ichi、Kawano Shintaro、Kiyoshima Tamotsu
- Journal Title
  
  Pathology - Research and Practice
  
  Volume: 254 Pages: 155148-155148
- DOI
  10.1016/j.prp.2024.155148
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0262, KAKENHI-PROJECT-20K10096, KAKENHI-PROJECT-23K27792
[Journal Article] Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation.2023
- Author(s)
  Alkhatib DZR, Thi Kim Truong T, Fujii S, Hasegawa K, Nagano R, Tajiri Y, Kiyoshima T.
- Journal Title
  
  Pathol Res Pract.
  
  Volume: 246 Pages: 154493-154493
- DOI
  10.1016/j.prp.2023.154493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10096, KAKENHI-PROJECT-21K09843, KAKENHI-PROJECT-22K17017, KAKENHI-PROJECT-23K27792
[Journal Article] The Semaphorin 3A-AKT axis-mediated cell proliferation in salivary gland morphogenesis and adenoid cystic carcinoma pathogenesis.2022
- Author(s)
  Fujii S, Fujimoto T, Hasegawa K, Nagano R, Ishibashi T, Kurppa KJ, Mikami Y, Kokura M, Tajiri Y, Kibe T, Wada H, Wada N, Kishida S, Higuchi Y, Kiyoshima T.
- Journal Title
  
  Pathol Res Pract.
  
  Volume: 236 Pages: 153991-153991
- DOI
  10.1016/j.prp.2022.153991
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10096, KAKENHI-PROJECT-21K09843, KAKENHI-PROJECT-19K19235, KAKENHI-PROJECT-22K17017, KAKENHI-PROJECT-20K09906, KAKENHI-PROJECT-20K10107
[Journal Article] The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation.2020
- Author(s)
  Fujii S., Tajiri, Y., Hasegawa, K., Matsumoto,S., Yoshimoto, RU., Wada, H., Kishida, S., Kido, MA., Yoshikawa, H., Ozeki, S., Kiyoshima, T.
- Journal Title
  
  Lab Invest.
  
  Volume: 100(2) Issue: 2 Pages: 311-323
- DOI
  10.1038/s41374-019-0357-z
- NAID
  120006938538
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11616, KAKENHI-PROJECT-19K10302, KAKENHI-PROJECT-18J11575, KAKENHI-PROJECT-19K18966
[Presentation] ヒト口腔扁平上皮癌に高発現した機械受容器TRPV4はCaMKII/AKTシグナル伝達を介して癌細胞の増殖を制御する2020
- Author(s)
  田尻祐大、藤井慎介、清島保
- Organizer
  第62回　歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10302
[Presentation] 機械受容器TRPV4はヒト口腔扁平上皮癌細胞の増殖を制御する2020
- Author(s)
  田尻祐大、藤井慎介、大関悟、清島保
- Organizer
  第109回　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K10302
[Presentation] TRPV4はヒト口腔扁平上皮癌細胞の増殖を制御する2020
- Author(s)
  田尻祐大、藤井慎介、吉川博政、清島保
- Organizer
  第65回　日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10302
[Presentation] TRPV4を介したカルシウム細胞内流入はCaMKII/AKTシグナル伝達を活性化し口腔扁平上皮癌細胞の増殖を促進する2020
- Author(s)
  田尻祐大、藤井慎介、清島保
- Organizer
  第97回　九大病理研究会
- Data Source
  KAKENHI-PROJECT-19K10302
[Presentation] 機械受容器TRPV4はヒト口腔癌細胞の増殖を制御する2019
- Author(s)
  藤井慎介、田尻祐大、大関悟、清島保
- Organizer
  第108回日本病理学会
- Data Source
  KAKENHI-PROJECT-19K10302

1. 清島保 (20264054)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. 藤井慎介 (60452786)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. 自見英治郎 (40276598)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 長谷川佳那 (30793989)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. ozeki satoru (80117077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 川野真太郎 (00398067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 和田裕子 (70380706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 城戸瑞穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tajiri Yudai 田尻 祐大

Research Projects

Research Products

Co-Researchers

Elucidation of the molecular mechanism by which nerve-cancer connections promote neuroinvasion in salivary gland malignant tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of resistance acquisition to super-enhancer-targeted anticancer therapies and novel strategies based on this mechanism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of the instability among mutant epithelial cells, adjacent normal epithelial cells and stromal cells to develop strategies for screening and very early detection of cancer.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of TRP signal activation mechanism in tumor-stromal seqence in oral tumor and its clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A new anti-cancer therapeutic strategy targeting the interrelation between tumorous mechanical extracellular microenvironment and novel oncogene-related gene signaling

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Wnt/β-catenin-C-kit axis may play a role in adenoid cystic carcinoma prognostication2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Semaphorin 3A-AKT axis-mediated cell proliferation in salivary gland morphogenesis and adenoid cystic carcinoma pathogenesis.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] ヒト口腔扁平上皮癌に高発現した機械受容器TRPV4はCaMKII/AKTシグナル伝達を介して癌細胞の増殖を制御する2020

Author(s)

Organizer

Data Source

[Presentation] 機械受容器TRPV4はヒト口腔扁平上皮癌細胞の増殖を制御する2020

Author(s)

Organizer

Data Source

[Presentation] TRPV4はヒト口腔扁平上皮癌細胞の増殖を制御する2020

Author(s)

Organizer

Data Source

[Presentation] TRPV4を介したカルシウム細胞内流入はCaMKII/AKTシグナル伝達を活性化し口腔扁平上皮癌細胞の増殖を促進する2020

Author(s)

Organizer

Data Source

[Presentation] 機械受容器TRPV4はヒト口腔癌細胞の増殖を制御する2019

Author(s)

Organizer

Data Source

Tajiri Yudai 田尻祐大