INOUE Tsuyoshi 井上剛

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Inoue Tsuyoshi 井上剛

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Researcher Number	30821665
Other IDs
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(医学系), 教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 長崎大学, 医歯薬学総合研究科(医学系), 教授 2018 – 2020: 東京大学, 医学部附属病院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / 0902:General internal medicine and related fields Except Principal Investigator Basic Section 55050:Anesthesiology-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 57050:Prosthodontics-related / Basic Section 56050:Otorhinolaryngology-related / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 腎臓 / 自律神経 / 急性腎障害 / 腎交感神経 / オプトジェネティクス / マクロファージ / 迷走神経刺激 Except Principal Investigator 循環制御 / 高血圧 / 周術期 … More / 自律神経 / 迷走神経 / アドレナリン / 副腎 / 交感神経 / デノスマブ / ビスホスホネート製剤 / 病態形成機構 / 細胞療法 / DRONJ / BRONJ / 極性変化 / 1細胞解析 / 階層構造 / マクロファージ / MRONJ / 薬剤関連顎骨壊死 / 放射線 / 瘢痕声帯 / シングルセルRNAシーケンス / プロテオミクス / イムノフェノタイピング / シングルセルRNAシーケンス（scRNAseq） / TAFRO / iMCD-IPL / iMCD-NOS / iMCD-TAFRO / 尿細管間質線維化 / ATF6 / 脂質毒性 / 脂質代謝 / エネルギー代謝 / 急性腎不全 / cGAS-STING経路 / ミトコンドリアDNA / 慢性腎臓病 / IFT88 / オルガネラクロストーク / 尿細管細胞代謝 / オルガネラ間相互作用 / 尿細管炎症 / 尿細管脂質代謝 / 一次繊毛 / オルガネラストレス / ミトコンドリアストレス / 小胞体ストレス Less

周術期血圧制御向上のための、免疫細胞による新規高血圧誘導メカニズムの解明
- Principal Investigator
  
  宮崎友理
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Nagasaki University
マクロファージを標的とした、放射線照射後声帯炎の予防に関する基礎的研究
- Principal Investigator
  
  熊井良彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Nagasaki University
Strategy for prevention and reduction of aspiration pneumonia and extension of healthy life expectancy by activation of dietary neuro-immune system
- Principal Investigator
  
  安部力
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gifu University
特発性多中心性キャッスルマン病の病型をクラスタリングする分子基盤研究
- Principal Investigator
  
  川上純
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
オプトジェネティクスの技術を活用した腎交感神経の機能解明Principal Investigator
- Principal Investigator
  
  井上剛
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Nagasaki University
Understanding of pathophysiology and development of treatment strategy for MRONJ based on the hierarchical structure of macrophages
- Principal Investigator
  
  黒嶋伸一郎
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57050:Prosthodontics-related
- Research Institution
  Hokkaido University
  Nagasaki University
Mechanism of direct renal control by the autonomic nervous systemPrincipal Investigator
- Principal Investigator
  
  Inoue Tsuyoshi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Nagasaki University
Elucidation of immune cell activation mechanism in the cholinergic anti-inflammatory pathwayPrincipal Investigator
- Principal Investigator
  
  Inoue Tsuyoshi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0902:General internal medicine and related fields
- Research Institution
  The University of Tokyo
Molecular mechanism of organelle crosstalk on organ homeostasis in aging and disease
- Principal Investigator
  
  Inagi Reiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Bone marrow stromal cell antigen-1 deficiency protects from acute kidney injury2024
- Author(s)
  Inoue Tsuyoshi、Umene Ryusuke、Sung Sun-Sang J.、Tanaka Shinji、Huang Liping、Yao Junlan、Hashimoto Noritatsu、Wu Chia-Hsien、Nakamura Yasuna、Nishino Tomoya、Ye Hong、Rosin Diane L.、Ishihara Katsuhiko、Okusa Mark D.
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 326 Issue: 2 Pages: F167-F177
- DOI
  10.1152/ajprenal.00175.2023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15251, KAKENHI-PROJECT-22K16107, KAKENHI-PROJECT-23K24350
[Journal Article] Repeated activation of C1 neurons in medulla oblongata decreases anti-inflammatory effect via the hypofunction of the adrenal gland adrenergic response2023
- Author(s)
  Chikara Abe, Chikako Katayama, Murat Bazek, Yasuna Nakamura, Kento Ohbayashi, Kazuhiro Horii, Chisato Fujimoto, Mamoru Tanida, Yusaku Iwasaki, Tsuyoshi Inoue, Fumiaki Nin, Hironobu Morita
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 111 Pages: 138-150
- DOI
  10.1016/j.bbi.2023.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-23K21476, KAKENHI-PROJECT-22K19617, KAKENHI-PROJECT-23K24350, KAKENHI-PROJECT-23K28032
[Journal Article] Alpha 7 nicotinic acetylcholine receptors signaling boosts cell-cell interactions in macrophages effecting anti-inflammatory and organ protection2023
- Author(s)
  Nakamura Yasuna、Matsumoto Hirotaka、Wu Chia-Hsien、Fukaya Daichi、Uni Rie、Hirakawa Yosuke、Katagiri Mikako、Yamada Shintaro、Ko Toshiyuki、Nomura Seitaro、Wada Youichiro、Komuro Issei、Nangaku Masaomi、Inagi Reiko、Inoue Tsuyoshi
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 666-666
- DOI
  10.1038/s42003-023-05051-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16107, KAKENHI-PROJECT-20KK0174, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-23K22779, KAKENHI-PROJECT-23K24350
[Journal Article] Induction of tetraspanin 13 contributes to the synergistic anti-inflammatory effects of parasympathetic and sympathetic stimulation in macrophages2023
- Author(s)
  Umene Ryusuke、Nakamura Yasuna、Wu Chia-Hsien、Muta Kumiko、Nishino Tomoya、Inoue Tsuyoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 665 Pages: 187-194
- DOI
  10.1016/j.bbrc.2023.04.118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16107, KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-22K16222, KAKENHI-PROJECT-23K24350
[Journal Article] Tolerogenic dendritic cells: promising cell therapy for acute kidney injury2023
- Author(s)
  Nakamura Yasuna、Inoue Tsuyoshi
- Journal Title
  
  Kidney International
  
  Volume: 104 Issue: 3 Pages: 420-422
- DOI
  10.1016/j.kint.2023.06.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24350
[Journal Article] Efficacy of Lactococcus lactis strain plasma (LC-Plasma) in easing symptoms in patients with mild coronavirus disease (COVID-19): protocol for an exploratory, multicenter, double-blinded, randomized controlled trial (PLATEAU study).2022
- Author(s)
  Yamamoto K, Hosogaya N, Inoue T, Jounai K, Tsuji R, Fujiwara D, Yanagihara K, Izumikawa K, Mukae H.
- Journal Title
  
  BMJ Open
  
  Volume: 12 Issue: 9 Pages: e061172-e061172
- DOI
  10.1136/bmjopen-2022-061172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08506, KAKENHI-PROJECT-23K24350
[Journal Article] Role of autonomic system imbalance in neurogenic pulmonary oedema2022
- Author(s)
  Yang Aobing、Liu Bin、Inoue Tsuyoshi
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 55 Issue: 6 Pages: 1645-1657
- DOI
  10.1111/ejn.15648
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24350
[Journal Article] Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney2022
- Author(s)
  Tanaka Shinji、Zheng Shuqiu、Kharel Yugesh、Fritzemeier Russell G.、Huang Tao、Foster Daniel、Poudel Nabin、Goggins Eibhlin、Yamaoka Yusuke、Rudnicka Kinga P.、Lipsey Jonathan E.、Radel Hope V.、Ryuh Sophia M.、Inoue Tsuyoshi、Yao Junlan、Rosin Diane L.、Schwab Susan R.、Santos Webster L.、Lynch Kevin R.、Okusa Mark D.
- Journal Title
  
  Science Translational Medicine
  
  Volume: 14 Issue: 658
- DOI
  10.1126/scitranslmed.abj2681
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24350
[Journal Article] Activation of α7 nicotinic acetylcholine receptors attenuates monocyte endothelial adhesion through FUT7 inhibition2022
- Author(s)
  Wu Chia-Hsien、Inoue Tsuyoshi、Nakamura Yasuna、Uni Rie、Hasegawa Sho、Maekawa Hiroshi、Sugahara Mai、Wada Youichiro、Tanaka Tetsuhiro、Nangaku Masaomi、Inagi Reiko
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 89-96
- DOI
  10.1016/j.bbrc.2021.12.094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159, KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-22K16107
[Journal Article] Bone marrow stromal cell antigen-1 (CD157) regulated by sphingosine kinase 2 mediates kidney fibrosis2022
- Author(s)
  Inoue T, Nakamura Y, Tanaka S, Kohro T, Li LX, Huang L, Yao J, Kawamura S, Inoue R, Nishi H, Fukaya D, Uni R, Hasegawa S, Inagi R, Umene R, Wu CH, Ye H, Bajwa A, Rosin DL, Ishihara K, Nangaku M, Wada Y, Okusa MD
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 9 Pages: 993698-993698
- DOI
  10.3389/fmed.2022.993698
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08222, KAKENHI-PROJECT-21K16159, KAKENHI-PROJECT-20KK0174, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-23K24350
[Journal Article] Lysophosphatidylcholine mediates fast decline in kidney function in diabetic kidney disease2022
- Author(s)
  Yoshioka Kentaro、Hirakawa Yosuke、Kurano Makoto、Ube Yuko、Ono Yoko、Kojima Kensuke、Iwama Taiga、Kano Kuniyuki、Hasegawa Sho、Inoue Tsuyoshi、Shimada Takashi、Aoki Junken、Yatomi Yutaka、Nangaku Masaomi、Inagi Reiko
- Journal Title
  
  Kidney International
  
  Volume: 101 Issue: 3 Pages: 510-526
- DOI
  10.1016/j.kint.2021.10.039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159
[Journal Article] Decreased IFT88 expression with primary cilia shortening causes mitochondrial dysfunction in cisplatin-induced tubular injury2021
- Author(s)
  Fujii Rie、Hasegawa Sho、Maekawa Hiroshi、Inoue Tsuyoshi、Yoshioka Kentaro、Uni Rie、Ikeda Yoichiro、Nangaku Masaomi、Inagi Reiko
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 321 Issue: 3 Pages: F278-F292
- DOI
  10.1152/ajprenal.00673.2020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159
[Journal Article] Vagus nerve stimulation activates two distinct neuroimmune circuits converging in the spleen to protect mice from kidney injury2021
- Author(s)
  Tanaka Shinji、Abe Chikara、Abbott Stephen B. G.、Zheng Shuqiu、Yamaoka Yusuke、Lipsey Jonathan E.、Skrypnyk Nataliya I.、Yao Junlan、Inoue Tsuyoshi、Nash William T.、Stornetta Daniel S.、Rosin Diane L.、Stornetta Ruth L.、Guyenet Patrice G.、Okusa Mark D.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 12
- DOI
  10.1073/pnas.2021758118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17242
[Journal Article] Neuroimmune system-mediated renal protection mechanisms2021
- Author(s)
  Inoue Tsuyoshi
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 25 Issue: 9 Pages: 915-924
- DOI
  10.1007/s10157-021-02062-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17242
[Journal Article] Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells2020
- Author(s)
  Higashijima Y, Matsui Y, Shimamura T, Nakaki R, Nagai N, Tsutsumi S, Abe Y, Link VM, Osaka M, Yoshida M, Watanabe R, Tanaka T, Taguchi A, Miura M, Ruan X, Li G, Inoue T, Nangaku M, Kimura H, Furukawa T, Aburatani H, Wada Y, Ruan Y, Glass CK, Kanki Y
- Journal Title
  
  The EMBO Journal
  
  Volume: 39 Issue: 7 Pages: 1-1
- DOI
  10.15252/embj.2019103949
- NAID
  120006902140
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23850, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-18H04899, KAKENHI-PLANNED-18H05527, KAKENHI-PUBLICLY-19H05210, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-17J07088, KAKENHI-PROJECT-17K15991, KAKENHI-PROJECT-19K21297, KAKENHI-PROJECT-20K09448, KAKENHI-PROJECT-20K21832, KAKENHI-PROJECT-20K17242, KAKENHI-PUBLICLY-20H04841, KAKENHI-PROJECT-18H02803, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-19K22679, KAKENHI-ORGANIZER-19H05739, KAKENHI-PROJECT-18H03207, KAKENHI-PROJECT-20H03432
[Journal Article] Vagus nerve stimulation even after injury ameliorates cisplatin-induced nephropathy via reducing macrophage infiltration2020
- Author(s)
  Uni Rie、Inoue Tsuyoshi、Nakamura Yasuna、Fukaya Daichi、Hasegawa Sho、Wu Chia-Hsien、Fujii Rie、Surattichaiyakul Bongkod、Peerapanyasut Wachirasek、Ozeki Atsuko、Akimitsu Nobuyoshi、Wada Youichiro、Nangaku Masaomi、Inagi Reiko
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 9472-9472
- DOI
  10.1038/s41598-020-66295-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-19K22679
[Journal Article] Neuroimmune interactions and kidney disease.2019
- Author(s)
  Hasegawa S, Inoue T, Inagi R.
- Journal Title
  
  Kidney Res Clin Pract.
  
  Volume: 38 Issue: 3 Pages: 282-294
- DOI
  10.23876/j.krcp.19.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-19J11928, KAKENHI-PROJECT-19K21297
[Journal Article] ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis2019
- Author(s)
  Jao Tzu-Ming、Nangaku Masaomi、Wu Chia-Hsien、Sugahara Mai、Saito Hisako、Maekawa Hiroshi、Ishimoto Yu、Aoe Mari、Inoue Tsuyoshi、Tanaka Tetsuhiro、Staels Bart、Mori Kazutoshi、Inagi Reiko
- Journal Title
  
  Kidney International
  
  Volume: 95 Issue: 3 Pages: 577-589
- DOI
  10.1016/j.kint.2018.09.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19K21297, KAKENHI-PROJECT-17H01432
[Journal Article] Organelle crosstalk in the kidney2019
- Author(s)
  Inoue Tsuyoshi、Maekawa Hiroshi、Inagi Reiko
- Journal Title
  
  Kidney International
  
  Volume: 印刷中 Issue: 6 Pages: 1318-1325
- DOI
  10.1016/j.kint.2018.11.035
- NAID
  40022012955
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-19K21297
[Journal Article] Mitochondrial damage causes inflammation via cGAS-STING signaling in acute kidney injury2019
- Author(s)
  Hiroshi Maekawa, Tsuyoshi Inoue, haruki Ouchi, Tzu-Ming Jao, Reiko Inoue, Hiroshi Nishi, Rie Fujii, Fumiyoshi Ishidate, Tetsuhiro Tanaka, Yosuke Tanaka, Nobutaka Hirokawa, Masaomi Nangaku, Reiko Inagi
- Journal Title
  
  Cell Reports
  
  Volume: 29 Issue: 5 Pages: 1261-1273
- DOI
  10.1016/j.celrep.2019.09.050
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08232, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-19K21297
[Journal Article] Non-canonical cholinergic anti-inflammatory pathway-mediated activation of peritoneal macrophages induces Hes1 and blocks ischemia/ reperfusion injury in the kidney.2019
- Author(s)
  Inoue T,Abe C, Kohro T, Tanaka S, Huang L, Yao J, Zheng S, Ye H, Inagi R, Stornetta RL, Rosin DL, Nangaku M, Wada Y, Okusa MD
- Journal Title
  
  Kidney International
  
  Volume: 95(3) Issue: 3 Pages: 563-576
- DOI
  10.1016/j.kint.2018.09.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19K21297, KAKENHI-ORGANIZER-15H05935
[Journal Article] Bioelectronic Approaches to Control Neuroimmune Interactions in Acute Kidney Injury2019
- Author(s)
  Inoue Tsuyoshi、Tanaka Shinji、Rosin Diane L.、Okusa Mark D.
- Journal Title
  
  Cold Spring Harbor Perspectives in Medicine
  
  Volume: 9 Issue: 6 Pages: a034231-a034231
- DOI
  10.1101/cshperspect.a034231
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21297
[Journal Article] Lipotoxicity(脂肪毒性)2018
- Author(s)
  藤井理恵、井上剛、稲城玲子
- Journal Title
  
  腎臓内科・泌尿器科
  
  Volume: ８ Pages: 370-378
- NAID
  40021706180
- Data Source
  KAKENHI-PROJECT-18H02727
[Presentation] 自律神経-免疫連関による腎病態制御メカニズム2023
- Author(s)
  井上　剛
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] Optogenetics in AKI2023
- Author(s)
  井上　剛
- Organizer
  The ISN World Congress of Nephrology 2023 (WCN’23)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] 神経免疫を介した連関機序2023
- Author(s)
  井上　剛
- Organizer
  第66回日本腎臓学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] 自律神経を介した抗炎症・臓器保護メカニズム2023
- Author(s)
  井上　剛
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] 腎臓と神経のクロストーク2023
- Author(s)
  井上　剛
- Organizer
  第100回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] 自律神経-免疫連関による腎病態制御メカニズム2022
- Author(s)
  井上　剛
- Organizer
  第65回日本腎臓学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] AKIでの脳腎連関2022
- Author(s)
  井上　剛
- Organizer
  第67回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] Elucidation of anti-inflammatory and kidney protection mechanisms through nervous-immune systems using single cell RNA-seq2022
- Author(s)
  井上　剛
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] AKIと神経系のInteraction2022
- Author(s)
  井上　剛
- Organizer
  第52回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] 自律神経制御による腎不全予防戦略2022
- Author(s)
  井上　剛
- Organizer
  第99回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] 神経-免疫系を介した抗炎症・腎臓保護メカニズム2022
- Author(s)
  井上　剛
- Organizer
  第43回日本循環制御医学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] 自律神経制御による腎臓病進展抑制メカニズム2022
- Author(s)
  井上　剛
- Organizer
  第12回腎不全研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24350
[Presentation] 自律神経－免疫系を介した抗炎症・臓器保護メカニズム2022
- Author(s)
  井上　剛
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] 自律神経－免疫系を介した抗炎症メカニズム（Anti-inflammatory mechanism through autonomic-immune system）2021
- Author(s)
  井上剛
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] 自律神経-免疫系を介した抗炎症メカニズム(Anti-inflammatory mechanism through autonomic-immune system)2021
- Author(s)
  井上　剛
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] バージニア大学腎臓内科留学2021
- Author(s)
  井上　剛
- Organizer
  第44回日本分子生物学学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] Role of macrophages in the protective effect of the kidney through the autonomic nervous system2021
- Author(s)
  井上　剛
- Organizer
  ERA-EDTA-JSN joint symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] 脳腎連関を介した腎疾患進展抑制メカニズム2021
- Author(s)
  井上　剛
- Organizer
  第51回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] 自律神経系による炎症制御におけるマクロファージの役割2020
- Author(s)
  井上剛
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] 神経系－免疫系を介した腎保護メカニズム2020
- Author(s)
  井上剛
- Organizer
  第48回関東腎研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21297
[Presentation] Neuro-immune axis on kidney disease2020
- Author(s)
  井上剛
- Organizer
  第97回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21297
[Presentation] Neuro-immune systems-mediated renal protection mechanism2020
- Author(s)
  井上剛
- Organizer
  第63回日本腎臓学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17242
[Presentation] Renal protective effect through nervous and immune systems2019
- Author(s)
  井上剛
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21297
[Presentation] Neural-renal linkage through the immune system2019
- Author(s)
  井上剛
- Organizer
  第42回日本分子生物学学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21297
[Presentation] 急性腎障害における神経系-免疫系の関連2019
- Author(s)
  井上剛
- Organizer
  第49回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21297
[Presentation] 急性腎障害における脳腎連関2019
- Author(s)
  井上剛
- Organizer
  第62回日本腎臓学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21297
[Presentation] 腎障害における神経系と免疫系の関連2019
- Author(s)
  井上剛
- Organizer
  第28回日本病態生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21297
[Presentation] スフィンゴシンキナーゼ２の下流遺伝子Bst1は、腎虚血再灌流障害および腎臓線維化の進展に重要である2018
- Author(s)
  井上　剛、他
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02727

1. 安部力 (10585235)

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2. Inagi Reiko (50232509)

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3. 平川陽亮 (10780736)

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6. 西裕志 (90784174)

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8. 住吉玲美 (70859363)

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INOUE Tsuyoshi 井上 剛

Inoue Tsuyoshi 井上 剛

Research Projects

Research Products

Co-Researchers

周術期血圧制御向上のための、免疫細胞による新規高血圧誘導メカニズムの解明

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マクロファージを標的とした、放射線照射後声帯炎の予防に関する基礎的研究

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Strategy for prevention and reduction of aspiration pneumonia and extension of healthy life expectancy by activation of dietary neuro-immune system

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特発性多中心性キャッスルマン病の病型をクラスタリングする分子基盤研究

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オプトジェネティクスの技術を活用した腎交感神経の機能解明Principal Investigator

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Understanding of pathophysiology and development of treatment strategy for MRONJ based on the hierarchical structure of macrophages

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Mechanism of direct renal control by the autonomic nervous systemPrincipal Investigator

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Elucidation of immune cell activation mechanism in the cholinergic anti-inflammatory pathwayPrincipal Investigator

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Molecular mechanism of organelle crosstalk on organ homeostasis in aging and disease

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[Journal Article] Bone marrow stromal cell antigen-1 deficiency protects from acute kidney injury2024

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[Journal Article] Repeated activation of C1 neurons in medulla oblongata decreases anti-inflammatory effect via the hypofunction of the adrenal gland adrenergic response2023

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[Journal Article] Alpha 7 nicotinic acetylcholine receptors signaling boosts cell-cell interactions in macrophages effecting anti-inflammatory and organ protection2023

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[Journal Article] Induction of tetraspanin 13 contributes to the synergistic anti-inflammatory effects of parasympathetic and sympathetic stimulation in macrophages2023

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[Journal Article] Tolerogenic dendritic cells: promising cell therapy for acute kidney injury2023

INOUE Tsuyoshi 井上剛

Inoue Tsuyoshi 井上剛