Honda Takayuki 本多隆行

Researcher Number	30827259
Other IDs
Affiliation (Current)	2025: 東京科学大学, 東京科学大学病院, 助教
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 東京科学大学病院, 助教 2021 – 2023: 東京医科歯科大学, 東京医科歯科大学病院, 助教 2019 – 2020: 東京医科歯科大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator 間質性肺炎 / 腫瘍微小環境 / 肺癌 / ゲノム解析 / 空間トランスクリプトーム / 非小細胞肺癌 / 肺腺癌 / NKX2-1 / 肺発がん / 発がん / 遺伝子変異 / 肺がん

空間トランスクリプトームによるNKX2-1失活とIPがもたらす免疫逃避的微小環境の解明Principal Investigator
- Principal Investigator
  
  本多隆行
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Institute of Science Tokyo
The Elucidation of Driver-oncogene Independent Oncogenic Genome Aberrations Induced by Interstitial PneumoniaPrincipal Investigator
- Principal Investigator
  
  本多隆行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokyo Medical and Dental University
Search for the unique carcinogenic mechanisms of lung cancer with interstitial pneumoniaPrincipal Investigator
- Principal Investigator
  
  Honda Takayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokyo Medical and Dental University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] 肺発生系譜上の転写因子TTF-1 / NKX2-1の変異と間質性肺炎合併肺腺がんの関連性2023
- Author(s)
  望月晶史1,2), 本多隆行1,2), 白石航也1), 吉田幸弘3), 渡辺俊一3), 堀之内秀仁4), 谷田部恭5), 浜本隆二6), 宮崎泰成2), 河野隆志1)
- Journal Title
  
  日本肺サーファクタント・界面医学会雑誌
  
  Volume: 54 Pages: 24-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16166
[Journal Article] The possibility of mutations of RAS signaling genes and/or <i>TP53</i> in combination as a negative prognostic impact on pathological stage I non‐small cell lung cancer2023
- Author(s)
  Honda Takayuki、Seto Katsutoshi、Endo Satoshi、Takemoto Akira、Tanimoto Kousuke、Kobayashi Masashi、Kitano Masatake、Sakakibara Rie、Mitsumura Takahiro、Ishibashi Hironori、Inazawa Johji、Tanaka Toshihiro、Miyazaki Yasunari、Okubo Kenichi
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 19 Pages: 19406-19413
- DOI
  10.1002/cam4.6535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16166
[Journal Article] 間質性肺炎合併肺がんの発症機構2023
- Author(s)
  本多隆行, 望月晶史, 河野隆志, 宮崎泰成
- Journal Title
  
  呼吸器内科
  
  Volume: 44 Pages: 322-328
- NAID
  130007775580
- Data Source
  KAKENHI-PROJECT-22K16166
[Journal Article] Distribution of genetic alterations in high-risk early-stage cervical cancer patients treated with postoperative radiation therapy2021
- Author(s)
  Murakami Naoya、Asami Yuka、Yoshida Hiroshi、Takayanagi Daisuke、Hirose Sou、Kuno Ikumi、Takahashi Kazuaki、Matsuda Maiko、Shimada Yoko、Yamano Shotaro、Sunami Kuniko、Honda Takayuki、Nakahara Tomomi、Watanabe Tomoko、Okuma Kae、Kuroda Takafumi、Kohno Takashi、Kato Tomoyasu、Shiraishi Kouya、Itami Jun
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 10567-10567
- DOI
  10.1038/s41598-021-90139-0
- Data Source
  KAKENHI-PROJECT-19K17669
[Journal Article] Non-inferior clinical outcomes of immune checkpoint inhibitors in non-small cell lung cancer patients with interstitial lung disease2021
- Author(s)
  Tasaka Yuri、Honda Takayuki、Nishiyama Naoki、Miyazaki Yasunari、et al.
- Journal Title
  
  Lung Cancer
  
  Volume: 155 Pages: 120-126
- DOI
  10.1016/j.lungcan.2021.03.014
- Data Source
  KAKENHI-PROJECT-19K17669
[Journal Article] Genomic alterations in STK11 can predict clinical outcomes in cervical cancer patients2020
- Author(s)
  Hirose S, Murakami N, Takahashi K, Kuno I, Takayanagi D, Asami Y, Matsuda M, Shimada Y, Yamano S, Sunami K, Yoshida K, Honda T, Nakahara T, Watanabe T, Komatsu M, Hamamoto R, Kato MK, Matsumoto K, Okuma K, Kuroda T, Okamoto A, Itami J, Kohno T, Kato T, Shiraishi K, Yoshida H
- Journal Title
  
  Gynecologic Oncology
  
  Volume: 156 Issue: 1 Pages: 203-210
- DOI
  10.1016/j.ygyno.2019.10.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11297, KAKENHI-PROJECT-18K15654, KAKENHI-PROJECT-19K17669, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429
[Journal Article] Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women2020
- Author(s)
  Wong JYY, Zhang H, Hsiung CA, Goto A, et al.
- Journal Title
  
  Genomics
  
  Volume: 112 Issue: 2 Pages: 1223-1232
- DOI
  10.1016/j.ygeno.2019.07.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07454, KAKENHI-PROJECT-19K17669, KAKENHI-PROJECT-19H03559, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-20H03695
[Journal Article] Disruption in the balance between apolipoprotein A-I and mast cell chymase in chronic hypersensitivity pneumonitis.2020
- Author(s)
  Yukihisa Inoue, Tsukasa Okamoto, Takayuki Honda, Yoshihisa Nukui, Takumi Akashi, Tamiko Takemura, Minoru Tozuka, Yasunari Miyazaki
- Journal Title
  
  Immunity, inflammation and disease
  
  Volume: 8 Issue: 4 Pages: 659-671
- DOI
  10.1002/iid3.355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08515, KAKENHI-PROJECT-19K17669
[Journal Article] Simple prediction model for homologous recombination deficiency in breast cancers in adolescents and young adults.2020
- Author(s)
  Watanabe T, Honda T, Totsuka H, Yoshida M, Tanioka M, Shiraishi K, Shimada Y, Arai E, Ushiama M, Tamura K, Yoshida T, Kanai Y, Kohno T.
- Journal Title
  
  Breast Cancer Res Treat
  
  Volume: 182 Issue: 2 Pages: 491-502
- DOI
  10.1007/s10549-020-05716-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07444, KAKENHI-PROJECT-19K17669
[Journal Article] The Utility of Ground-Glass Attenuation Score for Anticancer Treatment-Related Acute Exacerbation of Interstitial Lung Disease Among Lung Cancer Patients With Interstitial Lung Disease2020
- Author(s)
  Naoki Nishiyama, Takayuki Honda, Manabu Sema, Tatsuo Kawahara, Yasuto Jin, Ichiro Natsume, Tomoshige Chiaki, Takaaki Yamashita, Yoshikazu Tsukada, Reiko Taki, Yoshihiro Miyashita, Kazuhito Saito, Tomoya Tateishi, Hiroyuki Sakashita, Yasunari Miyazaki
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 25 Issue: 2 Pages: 282-291
- DOI
  10.1007/s10147-019-01576-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17669
[Presentation] 受動喫煙が肺腺がんの発生・進行に及ぼす変異原性寄与2023
- Author(s)
  望月晶史1,2、白石航也1、本多隆行2、角南久仁子1,3、宮崎泰成2、吉田幸弘4、渡辺俊一4、堀之内秀仁5、谷田部恭6、浜本隆二7、河野隆志1
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16166
[Presentation] 肺腺がん発生における受動喫煙の変異原性寄与2023
- Author(s)
  望月晶史(国立がん研究センター研究所ゲノム生物), 白石航也, 本多隆行, 角南久仁子, 吉田幸弘, 堀之内秀仁, 谷田部恭, 浜本隆二, 河野隆志
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K16166
[Presentation] Mutations of RAS Signaling Genes and TP53 in Combination Have a Negative Prognostic Impact on Pathological Stage Ⅰ Non-small Cell Lung Cancer2022
- Author(s)
  Takayuki Honda, Katsutoshi Seto, Satoshi Endo, Akira Takemoto, Kousuke Tanimoto, Rie Sakakibara, Takahiro Mitsumura, Masashi Kobayashi, Hironori Ishibashi, Johji Inazawa, Toshihiro Takana, Yasunari Miyazaki, Kenichi Okubo
- Organizer
  第20回臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-22K16166
[Presentation] Whole genome sequencing of lung adenocarcinomas associated with usual interstitial pneumonia.2022
- Author(s)
  Mochizuki A, Akifumi Mochizuki, Kouya Shiraishi, Takayuki Honda, Yukihiro Yoshida, Yasushi Yatabe, Syuzo Kaneko, Ryuji Hamamoto, Takashi Kohno
- Organizer
  第81回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-22K16166
[Presentation] 肺発生系表上の転写因子TTF-1/NKX2-1の変異と間質性肺炎合併肺腺がんの関連性肺発生系表上の転写因子TTF-1/NKX2-1の変異と間質性肺炎合併肺腺がんの関連性.2022
- Author(s)
  望月晶史、本多隆行、宮崎泰成
- Organizer
  第58回日本肺サーファクタント・界面医学会
- Data Source
  KAKENHI-PROJECT-22K16166
[Presentation] Incidence of thromboembolism in lung cancer patients treated with immune checkpoint inhibitors and chemotherapy2021
- Author(s)
  Satoshi Endo, Tatsuo Kawahara, Takayuki Honda, Yasunari Miyazaki, et al.
- Organizer
  the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17669
[Presentation] Tumor immune-microenvironment of Malignant Pleural Mesothelioma2021
- Author(s)
  Yuting Yin, Rie Sakakibara, Takayuki Honda, Yasunari Miyazaki, et al
- Organizer
  The 62nd Annual Meeting of Japan Lung Cancer Society
- Data Source
  KAKENHI-PROJECT-19K17669
[Presentation] Identification of prognostic and therapeutic biomarker of tumor immune-micro-environment infiltrating lymphocytes INOF malignant pleural mesothelioma: A spatial analysis in Asian population2021
- Author(s)
  Yuting Yin, Rie Sakakibara, Takayuki Honda, Yasunari Miyazaki, et al
- Organizer
  the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17669
[Presentation] Distribution of Tumor Mutation Burden in Lung Adenocarcinoma Patients with Usual Interstitial Pneumonia2019
- Author(s)
  Honda T, Sakashita H, Masai K, Motoi M, Kobayashi M, Akashi T, Mimaki S, Tsuchihara K, Shiraishi K, Okubo K, Watanabe S, Tsuta K, Inase N, Miyazaki Y, Kohno T
- Organizer
  The 59th Annual Meeting of The Japanese Respiratory Society
- Data Source
  KAKENHI-PROJECT-19K17669

1. ARAI Eri

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 松本光司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 後藤明輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 宮崎泰成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Honda Takayuki 本多 隆行

Research Projects

Research Products

Co-Researchers

空間トランスクリプトームによるNKX2-1失活とIPがもたらす免疫逃避的微小環境の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Elucidation of Driver-oncogene Independent Oncogenic Genome Aberrations Induced by Interstitial PneumoniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for the unique carcinogenic mechanisms of lung cancer with interstitial pneumoniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] 肺発生系譜上の転写因子TTF-1 / NKX2-1の変異と間質性肺炎合併肺腺がんの関連性2023

Author(s)

Journal Title

Data Source

[Journal Article] The possibility of mutations of RAS signaling genes and/or <i>TP53</i> in combination as a negative prognostic impact on pathological stage I non‐small cell lung cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 間質性肺炎合併肺がんの発症機構2023

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Distribution of genetic alterations in high-risk early-stage cervical cancer patients treated with postoperative radiation therapy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Non-inferior clinical outcomes of immune checkpoint inhibitors in non-small cell lung cancer patients with interstitial lung disease2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genomic alterations in STK11 can predict clinical outcomes in cervical cancer patients2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Disruption in the balance between apolipoprotein A-I and mast cell chymase in chronic hypersensitivity pneumonitis.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simple prediction model for homologous recombination deficiency in breast cancers in adolescents and young adults.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Utility of Ground-Glass Attenuation Score for Anticancer Treatment-Related Acute Exacerbation of Interstitial Lung Disease Among Lung Cancer Patients With Interstitial Lung Disease2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 受動喫煙が肺腺がんの発生・進行に及ぼす変異原性寄与2023

Author(s)

Organizer

Data Source

[Presentation] 肺腺がん発生における受動喫煙の変異原性寄与2023

Author(s)

Organizer

Data Source

[Presentation] Mutations of RAS Signaling Genes and TP53 in Combination Have a Negative Prognostic Impact on Pathological Stage Ⅰ Non-small Cell Lung Cancer2022

Honda Takayuki 本多隆行