TOKIWA HIROYUKI 常盤洋之

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常盤洋之トキワヒロユキ

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Researcher Number	30834197
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 特任助教
Affiliation (based on the past Project Information) *help	2025: 東京大学, 医学部附属病院, 特任助教 2023: 東京大学, 医学部附属病院, 特任臨床医 2022: 東京大学, 医学部附属病院, 届出診療員
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 肺高血圧 / non-genomic pathway / エストロゲン / 肺動脈性肺高血圧症

エストロゲンのnon-genomic pathwayによる肺動脈性肺高血圧症の炎症制御機構の解明Principal Investigator
- Principal Investigator
  
  常盤洋之
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
非ゲノム経路に着目したエストロゲンによる肺動脈性肺高血圧症の病態制御機構の解明Principal Investigator
- Principal Investigator
  
  常盤洋之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo

All 2023 2022

All Journal Article Presentation

[Journal Article] Tie2-Cre-Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury2023
- Author(s)
  Liu Pang-Yen、Fukuma Nobuaki、Hiroi Yukio、Kunita Akiko、Tokiwa Hiroyuki、Ueda Kazutaka、Kariya Taro、Numata Genri、Adachi Yusuke、Tajima Miyu、Toyoda Masayuki、Li Yuxin、Noma Kensuke、Harada Mutsuo、Toko Haruhiro、Ushiku Tetsuo、Kanai Yoshimitsu、Takimoto Eiki、Liao James K.、Komuro Issei
- Journal Title
  
  JACC: Basic to Translational Science
  
  Volume: 8 Issue: 1 Pages: 55-67
- DOI
  10.1016/j.jacbts.2022.07.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-20K07422, KAKENHI-PROJECT-22K08515, KAKENHI-PROJECT-21H02908, KAKENHI-PROJECT-20K07739
[Journal Article] The emerging role of estrogen's non-nuclear signaling in the cardiovascular disease2023
- Author(s)
  Tokiwa Hiroyuki、Ueda Kazutaka、Takimoto Eiki
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 10
- DOI
  10.3389/fcvm.2023.1127340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-21H02908
[Journal Article] PGC-1α-mediated angiogenesis prevents pulmonary hypertension in mice2023
- Author(s)
  Fujiwara T, Takeda N, Hara H, Ishii S, Numata G, Tokiwa H, Katoh M, Maemura S, Suzuki T, Takiguchi H, Yanase T, Kubota Y, Nomura S, Hatano M, Ueda K, Harada M, Toko H, Takimoto E, Akazawa H, Morita H, Nishimura S, Komuro I.
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 17 Pages: 162632-162632
- DOI
  10.1172/jci.insight.162632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16066, KAKENHI-PROJECT-22K08276, KAKENHI-PROJECT-23K07473, KAKENHI-PROJECT-21K08023, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-21H02908, KAKENHI-PROJECT-23K27352
[Journal Article] A pacing-controlled protocol for frequency-diastolic relations distinguishes diastolic dysfunction specific to a mouse HFpEF model2022
- Author(s)
  Numata Genri、Takimoto Eiki、Kariya Taro、Adachi Yusuke、Tokiwa Hiroyuki、Toyoda Masayuki、Mafune Ryo、Saito Yoshihiro、Nakamura Shun、Ueda Kazutaka、Ikeda Yuichi、Komuro Issei
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 323 Issue: 3 Pages: H523-H527
- DOI
  10.1152/ajpheart.00241.2022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-22KJ1202, KAKENHI-PROJECT-21H02908
[Journal Article] Endoplasmic reticulum stress-activated nuclear factor-kappa B signaling pathway induces the upregulation of cardiomyocyte dopamine D1 receptor in heart failure2022
- Author(s)
  Shun Nakamura, Genri Numata, Toshihiro Yamaguchi, Hiroyuki Tokiwa, Yasutomi Higashikuni, Seitaro Nomura, Tetsuo Sasano, Eiki Takimoto, Issei Komuro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 637 Pages: 247-253
- DOI
  10.1016/j.bbrc.2022.11.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08098, KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-22KJ1202
[Presentation] ACHD-sPAHの治療指針をどう立てるべきか2023
- Author(s)
  常盤洋之
- Organizer
  第25回日本成人先天性心疾患学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K16064
[Presentation] 経皮的心房中隔欠損閉鎖術が心機能に及ぼす効果に関する心臓 MRI をもちいた解析2023
- Author(s)
  常盤洋之、齊藤暁人、稲葉俊郎、後藤耕策、梅井正彦、相馬桂、上原雅恵、小室一成、八尾厚史
- Organizer
  第24回日本成人先天性心疾患学会
- Data Source
  KAKENHI-PROJECT-22K16064
[Presentation] Endothelial-specific inactivation of non-nuclear estrogen receptor-α signaling impairs estrogen protection against vascular injury2022
- Author(s)
  Hiroyuki Tokiwa
- Organizer
  第6回日本循環器学会基礎研究フォーラム（BCVR）
- Data Source
  KAKENHI-PROJECT-22K16064

1. 東邦康智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 瀧本英樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 山口敏弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOKIWA HIROYUKI 常盤 洋之

常盤 洋之 トキワ ヒロユキ

Research Projects

Research Products

Co-Researchers

エストロゲンのnon-genomic pathwayによる肺動脈性肺高血圧症の炎症制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非ゲノム経路に着目したエストロゲンによる肺動脈性肺高血圧症の病態制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Tie2-Cre-Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The emerging role of estrogen's non-nuclear signaling in the cardiovascular disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PGC-1α-mediated angiogenesis prevents pulmonary hypertension in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A pacing-controlled protocol for frequency-diastolic relations distinguishes diastolic dysfunction specific to a mouse HFpEF model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endoplasmic reticulum stress-activated nuclear factor-kappa B signaling pathway induces the upregulation of cardiomyocyte dopamine D1 receptor in heart failure2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] ACHD-sPAHの治療指針をどう立てるべきか2023

Author(s)

Organizer

Data Source

[Presentation] 経皮的心房中隔欠損閉鎖術が心機能に及ぼす効果に関する心臓 MRI をもちいた解析2023

Author(s)

Organizer

Data Source

[Presentation] Endothelial-specific inactivation of non-nuclear estrogen receptor-α signaling impairs estrogen protection against vascular injury2022

Author(s)

Organizer

Data Source

TOKIWA HIROYUKI 常盤洋之

常盤洋之トキワヒロユキ