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Matsumoto Minoru  松本 穣

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MATSUMOTO Minoru  松本 穣

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Researcher Number 30836250
Other IDs
Affiliation (Current) 2025: 徳島大学, 大学院医歯薬学研究部(医学域), 講師
Affiliation (based on the past Project Information) *help 2025: 徳島大学, 大学院医歯薬学研究部(医学域), 講師
2021 – 2023: 徳島大学, 大学院医歯薬学研究部(医学域), 講師
2019 – 2020: 徳島大学, 大学院医歯薬学研究部(医学域), 助教
Review Section/Research Field
Principal Investigator
Basic Section 49020:Human pathology-related / Basic Section 49030:Experimental pathology-related
Except Principal Investigator
Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 49070:Immunology-related / Basic Section 54020:Connective tissue disease and allergy-related
Keywords
Principal Investigator
空間的シングルセル解析 / 空間的トランスクリプトーム / 胸腺上皮性腫瘍 / 胸腺癌 / 糖尿病 / Ⅰ型糖尿病 / NOD / Xcr1陽性樹状細胞 / I型糖尿病 / AIRE … More
Except Principal Investigator
… More 胸腺 / 遺伝子改変マウス / 自己免疫疾患 / 自己寛容 / 転写因子 / 自己抗原 / Aire / I型糖尿病 / AIRE Less
  • Research Projects

    (6 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (5 People)
  •  細胞起源に基づく胸腺上皮性腫瘍の病態解明Principal Investigator

    • Principal Investigator
      松本 穣
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      The University of Tokushima
  •  空間的シングルセル解析による胸腺癌の病態解明Principal Investigator

    • Principal Investigator
      松本 穣
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      The University of Tokushima
  •  Complete understanding of Aire function through identifying its bona fide target genes

    • Principal Investigator
      松本 満
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      The University of Tokushima
  •  Solving the two enigmatic issues concerning thymic tolerance

    • Principal Investigator
      松本 満
    • Project Period (FY)
      2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      The University of Tokushima
  •  Pathological analysis of the mechanism underlying resistance to diabetes controlled by AIREPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Minoru
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      The University of Tokushima
  •  Elucidation of the pathogenesis of autoimmune diseases based on AIRE and development of novel therapies for the autoimmune diseases

    • Principal Investigator
      MATSUMOTO Mitsuru
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54020:Connective tissue disease and allergy-related
    • Research Institution
      The University of Tokushima

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation Book

  • [Book] Thymus Transcriptome and Cell Biology2019

    • Author(s)
      Minoru Matsumoto, Pedro M. Rodrigues, Laura Sousa, Koichi Tsuneyama, Mitsuru Matsumoto, Nuno L. Alves
    • Total Pages
      31
    • Publisher
      Springer International Publishing
    • ISBN
      9783030120399
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Book] Thymus Transcriptome and Cell Biology.2019

    • Author(s)
      Minoru Matsumoto, Pedro M. Rodrigues, Laura Sousa, Koichi Tsuneyama, Mitsuru Matsumoto, Nuno L. Alves
    • Total Pages
      31
    • Publisher
      Springer International Publishing
    • Data Source
      KAKENHI-PROJECT-19K16613
  • [Journal Article] Dispensable role of Aire in the CD11c+ conventional dendritic cells for antigen presentation and shaping the transcriptome.2023

    • Author(s)
      Miyazawa M, Nagao J, Morioka K, Matsumoto M, Morimoto J, Yoshida M, Oya T, Tsuneyama K, Yoshida H, Tanaka Y, Matsumoto M.
    • Journal Title

      Immunohorizons

      Volume: 7 Issue: 1 Pages: 140-158

    • DOI

      10.4049/immunohorizons.2200103

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07120, KAKENHI-PROJECT-20H00555, KAKENHI-PROJECT-22H02892, KAKENHI-PROJECT-20K16287, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-19H03699, KAKENHI-PROJECT-22K19437
  • [Journal Article] AIRE illuminates the feature of medullary thymic epithelial cells in thymic carcinoma.2023

    • Author(s)
      Matsumoto M, Ohmura T, Hanibuchi Y, Ichiyama-Shimizu M, Saijyo Y, Ogawa H, Miyazawa R, Morimoto J, Tsuneyama K, Matsumoto M, Oya T.
    • Journal Title

      Cancer Medicine

      Volume: 3 Issue: 8 Pages: 1-6

    • DOI

      10.1002/cam4.5777

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07120, KAKENHI-PROJECT-22H02892, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-19H03699, KAKENHI-PROJECT-22K07024, KAKENHI-PROJECT-22K19437
  • [Journal Article] Cooperative but distinct role of medullary thymic epithelial cells and dendritic cells in the production of regulatory T-cells in the thymus2023

    • Author(s)
      Morimoto J, Matsumoto M, Oya T, Tsuneyama K, Matsumoto M
    • Journal Title

      J. Immunol.

      Volume: - Issue: 11 Pages: 1-14

    • DOI

      10.4049/jimmunol.2200780

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H02892, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-19H03699, KAKENHI-PROJECT-22K07024, KAKENHI-PROJECT-22K07120, KAKENHI-PROJECT-22K19437
  • [Journal Article] Revisiting Aire and tissue-restricted antigens at single-cell resolution2023

    • Author(s)
      Matsumoto M, Yoshida H, Tsuneyama K, Oya T and Matsumoto M
    • Journal Title

      Frontiers in Immunology

      Volume: - Pages: 1-11

    • DOI

      10.3389/fimmu.2023.1176450

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H02892, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-19H03699, KAKENHI-PROJECT-22K07024, KAKENHI-PROJECT-22K19437
  • [Journal Article] A novel method to identify Post-Aire stages of medullary thymic epithelial cell differentiation2021

    • Author(s)
      Ferreirinha P, Ribeiro C, Morimoto J, Landry JJM, Matsumoto M, Meireles C, White AJ, Ohigashi I, Araujo L, Benes V, Takahama Y, Anderson G, Matsumoto M, Alves N
    • Journal Title

      European Journal of Immunology

      Volume: 51 Issue: 2 Pages: 311-318

    • DOI

      10.1002/eji.202048764

    • NAID

      120007153322

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07626, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-19H03699, KAKENHI-PLANNED-16H06496
  • [Journal Article] Aberrant type 1 immunity drives susceptibility to mucosal fungal infection2021

    • Author(s)
      T Break, V Oikonomou, N Dutzan, J Desai, M Swidergall, T Freiwald, D Chauss, O Harrison, J Alejo, D Williams, S Pittaluga, C-C Lee, N Bouladoux, M Swamydas, K Hoffman, T Greenwell-Wild, V Bruno, L Rosen, W Lwin, A Renteria, S Pontejo, J Shannon, I Myles, P Olbrich, E Ferre, M Schmitt, D Martin, M Matsumoto, et al.
    • Journal Title

      Science

      Volume: 371 Issue: 6526 Pages: 1-17

    • DOI

      10.1126/science.aay5731

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731, KAKENHI-PROJECT-19H03699, KAKENHI-PLANNED-16H06496
  • [Journal Article] 胸腺上皮細胞を対象とする自己免疫疾患への橋渡し研究の可能性2020

    • Author(s)
      森本純子、松本 穣、宮澤龍一郎、松本 満
    • Journal Title

      Precision Medicine 橋渡し研究の推進

      Volume: 1 Pages: 92-97

    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Journal Article] Aireを基軸とする自己免疫疾患の病態解明2020

    • Author(s)
      森本純子、宮澤龍一郎、松本 穣、松本 満
    • Journal Title

      別冊BIO Clinica

      Volume: 1 Pages: 90-95

    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Journal Article] Development of a new monoclonal antibody specific to mouse Vg6 chain2019

    • Author(s)
      Hatano S, Tun X, Noguchi N, Yue D, Yamada H, Sun X, Matsumoto M, Yoshikai Y.
    • Journal Title

      Life Sci Alliance

      Volume: 2 Issue: 3 Pages: 1-12

    • DOI

      10.26508/lsa.201900363

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PROJECT-19H03699, KAKENHI-PROJECT-18K19564, KAKENHI-PLANNED-16H06496
  • [Journal Article] AIRE - The Autoimmune Regulator2019

    • Author(s)
      Matsumoto Minoru、Nishijima Hitoshi、Morimoto Junko、Tsuneyama Koichi、Matsumoto Mitsuru
    • Journal Title

      eLS

      Volume: 1 Pages: 1-8

    • DOI

      10.1002/9780470015902.a0027281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08885, KAKENHI-PROJECT-18K19564, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06496, KAKENHI-PROJECT-16H05342, KAKENHI-PROJECT-19K16613
  • [Journal Article] Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms2019

    • Author(s)
      Matsumoto Minoru、Tsuneyama Koichi、Morimoto Junko、Hosomichi Kazuyoshi、Matsumoto Mitsuru、Nishijima Hitoshi
    • Journal Title

      International Immunology

      Volume: 32 Issue: 2 Pages: 117-131

    • DOI

      10.1093/intimm/dxz066

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-19K07626, KAKENHI-PROJECT-19K16613, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06502, KAKENHI-PUBLICLY-19H05344, KAKENHI-PROJECT-19H03699, KAKENHI-PROJECT-17K08885, KAKENHI-PROJECT-18K19564, KAKENHI-PLANNED-16H06496
  • [Journal Article] ヒトAIREを発現させたNODマウスに認められる自己免疫応答2019

    • Author(s)
      西嶋 仁、松本 満
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 71 Pages: 490-496

    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] シングルセル解析を用いた胸腺上皮細胞ならびに胸腺癌へのアプローチ2024

    • Author(s)
      松本 穣
    • Organizer
      第113回 日本病理学会総会 先端的分子病理学講習会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K14478
  • [Presentation] Aire suppresses CTLA-4 expression from medullary thymic epithelial cells to avoid autoimmunity2023

    • Author(s)
      Junko Morimoto, Mitsuru Matsumoto
    • Organizer
      THE 7TH INTERNATIONAL CONGRESS ON CONTROVERSIES IN RHEUMATOLOGY AND AUTOIMMUNITY
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19437
  • [Presentation] Aire suppresses CTLA-4 expression from medullary thymic epithelial cells to avoid autoimmunity2023

    • Author(s)
      Junko Morimoto, Mitsuru Matsumoto
    • Organizer
      THE 7TH INTERNATIONAL CONGRESS ON CONTROVERSIES IN RHEUMATOLOGY AND AUTOIMMUNITY
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H02892
  • [Presentation] Aire suppresses CTLA-4 expression from medullary thymic epithelial cells to avoid autoimmunity2023

    • Author(s)
      Junko Morimoto, Mitsuru Matsumoto
    • Organizer
      THE 7TH INTERNATIONAL CONGRESS ON CONTROVERSIES IN RHEUMATOLOGY AND AUTOIMMUNITY
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Autoimmune pathology caused by the abnormal function of thymic epithelial cells2022

    • Author(s)
      Mitsuru Matsumoto
    • Organizer
      第51回日本免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K19437
  • [Presentation] Elucidation of the pathogenesis of autoimmune disease: from serology toward molecular biology2022

    • Author(s)
      Mitsuru Matsumoto
    • Organizer
      The 8th IMCR Symposium on Endocrine and Metabolism : Beyond the Frontiers of Endocrinology & Metabolism
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H02892
  • [Presentation] Elucidation of the pathogenesis of autoimmune disease: from serology toward molecular biology2022

    • Author(s)
      Mitsuru Matsumoto
    • Organizer
      The 8th IMCR Symposium on Endocrine and Metabolism : Beyond the Frontiers of Endocrinology & Metabolism
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19437
  • [Presentation] Autoimmune pathology caused by the abnormal function of thymic epithelial cells2022

    • Author(s)
      Mitsuru Matsumoto
    • Organizer
      第51回日本免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H02892
  • [Presentation] Autoimmune pathology caused by the abnormal function of thymic epithelial cells2022

    • Author(s)
      Mitsuru Matsumoto
    • Organizer
      第51回日本免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Elucidation of the pathogenesis of autoimmune disease: from serology toward molecular biology2022

    • Author(s)
      Mitsuru Matsumoto
    • Organizer
      The 8th IMCR Symposium on Endocrine and Metabolism : Beyond the Frontiers of Endocrinology & Metabolism
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Tissue-specific autoimmunity controlled by Aire, a gene response for APECED2021

    • Author(s)
      Minoru Matsumoto, Hitoshi Nishijima, Junko Morimoto, Koichi Tsuneyama, Mitsuru Matsumoto
    • Organizer
      The Virtual World Conference on Rare Diseases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Aireレポーターマウスを用いた胸腺内Aire発現樹状細胞の解析2021

    • Author(s)
      松本 穣、尾矢剛志、松本 満
    • Organizer
      第40回日本胸腺研究会
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] 胸腺髄質上皮細胞からDCへの抗原転移におけるAireの役割2021

    • Author(s)
      森本 純子、松本 満
    • Organizer
      第40回日本胸腺研究会
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Characterization of Aire-expressing DCs with high-sensitivity and high-fidelity Aire-reporter strain2019

    • Author(s)
      Minoru Matsumoto, Hitoshi Nishijima, Ryuichiro Miyazawa, Junko Morimoto, Koichi Tsuneyama and Mitsuru Matsumoto.
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K16613
  • [Presentation] Aire-dependent establishment of self-tolerance2019

    • Author(s)
      Matsumoto M, Morimoto J, Matsumoto M, Tsuneyama K, Miyazawa R, Nishijima H
    • Organizer
      The 17th International Congress of Immunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Antigen transfer from thymic epithelial cells to DCs contributes to the production of thymic Tregs2019

    • Author(s)
      Junko Morimoto, Hitoshi Nishijima, Minoru Matsumoto, Mitsuru Matsumoto
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] 胸腺髄質上皮細胞に発現する転写調節因子Aireを用いた自己免疫病態の解析2019

    • Author(s)
      松本 満
    • Organizer
      第29回日本内分泌学会臨床内分泌代謝Update
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Aireを高発現する胸腺髄質上皮細胞の免疫学的機能とトランスクリプトーム解析2019

    • Author(s)
      西嶋 仁、杉田瑞季、森本純子、松本 穣、松本 満
    • Organizer
      第42回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Characterization of Aire-expressing DCs with a high-sensitivity and high-fidelity Aire-reporter strain2019

    • Author(s)
      Minoru Matsumoto, Hitoshi Nishijima, Ryuichiro Miyazawa, Junko Morimoto, Koichi Tsuneyama, Mitsuru Matsumoto
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms2019

    • Author(s)
      Minoru Matsumoto, Mitsuru Matsumoto
    • Organizer
      The 18th Awaji International Forum on Infection and Immunity
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] 胸腺におけるネオ・セルフ生成機構2019

    • Author(s)
      松本 満
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03699
  • [Presentation] Aire-dependent establishment of self-tolerance studied by genetically modified mice2019

    • Author(s)
      Mitsuru Matsumoto, Junko Morimoto, Minoru Matsumoto, Koichi Tsuneyama, Ryuichiro Miyazawa, Hitoshi Nishijima
    • Organizer
      EMBO Workshop ThymE
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03699
  • 1.  MATSUMOTO Mitsuru (60221595)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 31 results
  • 2.  森本 純子 (20451396)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 3.  西嶋 仁 (60425410)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 4.  宮澤 龍一郎 (70848374)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  常山 幸一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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