kunishita yosuke 國下洋輔

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KUNISHITA Yosuke 國下洋輔

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Researcher Number	30849972
Other IDs	https://orcid.org/0000-0002-3915-9276
Affiliation (Current)	2025: 横浜市立大学, 医学研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2020 – 2023: 横浜市立大学, 医学研究科, 客員研究員 2019: 横浜市立大学, 附属病院, 指導診療医
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / 0803:Pathology, infection/immunology, and related fields Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator SLE / 抗TRIM21抗体 / TRIM21 / インフラマソーム / B cell / IRF5 / 免疫グロブリン / Ⅰ型インターフェロン / 抗体産生 / B細胞 / 全身性エリテマトーデス … More Except Principal Investigator … More 膠原病 / TRIM / リソソーム / オートファジー Less

Therapeutic strategies for connective tissue diseases by targeting the autophagy-lysosomal pathway
- Principal Investigator
  
  吉見竜介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Yokohama City University
The association between TRIM21 and inflammasome in SLEPrincipal Investigator
- Principal Investigator
  
  國下洋輔
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Yokohama City University
The role of TRIM21 in B cell Abnormalities with Systemic Lupus ErythematosusPrincipal Investigator
- Principal Investigator
  
  KUNISHITA Yosuke
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  Yokohama City University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Anti-TRIM21 antibody is associated with aberrant B-cell function and type I interferon production in systemic lupus erythematosus2021
- Author(s)
  Kunishita Yosuke、Yoshimi Ryusuke、Kamiyama Reikou、Kishimoto Daiga、Komiya Takaaki、Sakurai Natsuki、Sugiyama Yumiko、Takase-Minegishi Kaoru、Kirino Yohei、Nagaoka Shouhei、Nakajima Hideaki
- Journal Title
  
  Lupus
  
  Volume: 30 Issue: 13 Pages: 2054-2065
- DOI
  10.1177/09612033211042293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08914, KAKENHI-PROJECT-18K16157, KAKENHI-PROJECT-20K17446
[Journal Article] TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis2020
- Author(s)
  Kunishita Yosuke、Yoshimi Ryusuke、Kamiyama Reikou、Kishimoto Daiga、Yoshida Koji、Hashimoto Eijin、Komiya Takaaki、Sakurai Natsuki、Sugiyama Yumiko、Kirino Yohei、Ozato Keiko、Nakajima Hideaki
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 98-98
- DOI
  10.3389/fimmu.2020.00098
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08914, KAKENHI-PROJECT-19K23847
[Presentation] 全身性エリテマトーデスにおける再燃と肥満の関連について LUNAレジストリを用いた観察研究2023
- Author(s)
  鈴木直樹, 吉見竜介, 秀川智春, 矢嶋宣幸, 櫻井菜月, 麹谷典子, 國下洋輔, 吉岡裕二, 岸本大河, 前田彩花, 平原理紗, 小宮孝章, 副島裕太郎, 濱田直樹, 土田奈緒美, 峯岸薫, 桐野洋平, 佐田憲映, 宮脇義亜, 一瀬邦弘, 梶山浩, 佐藤秀三, 下島恭弘, 藤原道雄, 木田節, 松尾祐介, 山本譲, 大野滋, 中島秀明
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08567
[Presentation] Effect of denosumab on bone destruction in rheumatoid arthritis in clinical practice: A prospective cohort study2023
- Author(s)
  KomiyaT, Yoshimi R, Kunishita Y, Kishimoto D, Sakurai N, Hidekawa C, Yoshioka Y, Suzuki N, Adachi S, Iizuka Y, Maeda A, Hirahara L, Hamada N, Tsuchida N, Soejima Y, Minegishi K, Kirino Y, Ohno S, Nakajima H
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08567
[Presentation] 全身性エリテマトーデス診療における共同意思決定がLLDAS達成に与える影響 TRUMP2-SLE研究2023
- Author(s)
  櫻井菜月, 吉見竜介, 矢嶋宣幸, 栗田宜明, 秀川智春, 小黒奈緒, 志田原健太, 林啓悟, 市川貴規, 岸田大, 宮脇義亜, 佐田憲映, 下島恭弘, 石川雄一, 吉岡裕二, 國下洋輔, 岸本大河, 峯岸薫, 桐野洋平, 大野滋, 中島秀明
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08567
[Presentation] SLE患者における低補体血症と感染症合併の関連について(第2報) LUNAレジストリを用いた観察研究2023
- Author(s)
  麹谷典子, 吉見竜介, 矢嶋宣幸, 杉山裕美子, 鈴木直樹, 秀川智春, 櫻井菜月, 吉岡裕二, 國下洋輔, 岸本大河, 前田彩花, 平原理紗, 小宮孝章, 副島裕太郎, 濱田直樹, 土田奈緒美, 峯岸薫, 桐野洋平, 佐田憲映, 宮脇義亜, 一瀬邦弘, 梶山浩, 佐藤秀三, 下島恭弘, 藤原道雄, 木田節松尾祐介, 西村啓佑, 大野滋, 中島秀明
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08567
[Presentation] 全身性エリテマトーデスにおける共同意思決定と医師への信頼度の関連についての前向きコホート研究：TRUMP2-SLE研究2023
- Author(s)
  吉見竜介, 矢嶋宣幸, 栗田宜明, 秀川智春, 櫻井菜月, 小黒奈緒, 志田原健太, 林啓悟, 市川貴規, 岸田大, 宮脇義亜, 佐田憲映, 下島恭弘, 石川雄一, 吉岡裕二, 國下洋輔, 岸本大河, 峯岸薫, 桐野洋平, 大野滋, 中島秀明
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08567
[Presentation] Does shared decision-making affect the quality of life in SLE patients?: the TRUMP2-SLE s2023
- Author(s)
  Hidekawa C, Yoshimi R, Yajima N, Kurita N, Sakurai N, Oguro N, Shidahara K, Hayashi K, Ichikawa T, Kishida D, Miyawaki Y, Sada KE, Shimojima Y, Ishikawa Y, Yoshioka Y, Kunishita Y, Kishimoto D, Minegishi K, Kirino Y, Ohno S, Nakajima H
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08567
[Presentation] 全身性エリテマトーデス診療における医師への信頼度に対して共同意思決定が与える影響: TRUMP2-SLE研究2022
- Author(s)
  吉見竜介, 秀川智春, 櫻井菜月, 矢嶋宣幸, 吉岡裕二, 岸本大河, 麹谷典子, 杉山裕美子, 國下洋輔, 水野広輝, 東谷佳奈, 佐藤雄一郎, 安達総一郎, 飯塚友紀, 前田彩花, 平原理紗, 小宮孝章, 副島裕太郎, 濱田直樹, 永井秀人, 土田奈緒美, 峯岸薫, 桐野洋平, 栗田宜明, 小黒奈緒, 宮脇義亜, 佐田憲映, 下島恭弘, 大野滋, 中島秀明
- Organizer
  第66回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K08567
[Presentation] Anti-TRIM21 antibody seropositivity is related to B-cell abnormalities in systemic lupus erythematosus2021
- Author(s)
  Yosuke Kunishita, Ryusuke Yoshimi, Takaaki Komiya, Natsuki Sakurai, Yumiko Sugiyama, Kaoru Takase-Minegishi, Yohei Kirino, Shouhei Nagaoka, Hideaki Nakajima
- Organizer
  IMMUNOLOGY 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23847
[Presentation] Anti-TRIM21 antibody is associated with type I interferon and B-cell abnormalities in systemic lupus erythematosus2021
- Author(s)
  國下洋輔、吉見竜介、鈴木直樹、飯塚友紀、三橋正季、小宮孝章、櫻井菜月、杉山裕美子、岸本大河、神山玲光、桐野洋平、長岡章平、中島秀明
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K23847
[Presentation] 全身性エリテマトーデスにおいて抗TRIM21抗体はTRIM21機能不全及びB細胞機能異常と関連する2020
- Author(s)
  國下洋輔、吉見竜介、鈴木直樹、飯塚友紀、三橋正季、小宮孝章、櫻井菜月、杉山裕美子、桐野洋平、長岡章平、中島秀明
- Organizer
  第48回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K23847
[Presentation] Dysfunction of Trim21 promotes aberrant plasmablasts differentiation in B cells of systemic lupus erythematosus due to the reduction of TRIM21-mediated ubiquitylation of IRF5 protein.2019
- Author(s)
  Yosuke Kunishita, Ryusuke Yoshimi, Reikou Kamiyama, Daiga Kishimoto, Koji Yoshida, Eijin Hashimoto, Yumiko Sugiyama, Takaaki Komiya, Yohei Kirino, Hideaki Nakajima
- Organizer
  the American College of Rheumatology’s 2019 annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23847

1. 吉見竜介 (70585265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. 中島秀明 (30217723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. 桐野洋平 (50468154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 峯岸薫 (40616877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

kunishita yosuke 國下 洋輔

KUNISHITA Yosuke 國下 洋輔

Research Projects

Research Products

Co-Researchers

Therapeutic strategies for connective tissue diseases by targeting the autophagy-lysosomal pathway

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The association between TRIM21 and inflammasome in SLEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of TRIM21 in B cell Abnormalities with Systemic Lupus ErythematosusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Anti-TRIM21 antibody is associated with aberrant B-cell function and type I interferon production in systemic lupus erythematosus2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 全身性エリテマトーデスにおける再燃と肥満の関連について LUNAレジストリを用いた観察研究2023

Author(s)

Organizer

Data Source

[Presentation] Effect of denosumab on bone destruction in rheumatoid arthritis in clinical practice: A prospective cohort study2023

Author(s)

Organizer

Data Source

[Presentation] 全身性エリテマトーデス診療における共同意思決定がLLDAS達成に与える影響 TRUMP2-SLE研究2023

Author(s)

Organizer

Data Source

[Presentation] SLE患者における低補体血症と感染症合併の関連について(第2報) LUNAレジストリを用いた観察研究2023

Author(s)

Organizer

Data Source

[Presentation] 全身性エリテマトーデスにおける共同意思決定と医師への信頼度の関連についての前向きコホート研究：TRUMP2-SLE研究2023

Author(s)

Organizer

Data Source

[Presentation] Does shared decision-making affect the quality of life in SLE patients?: the TRUMP2-SLE s2023

Author(s)

Organizer

Data Source

[Presentation] 全身性エリテマトーデス診療における医師への信頼度に対して共同意思決定が与える影響: TRUMP2-SLE研究2022

Author(s)

Organizer

Data Source

[Presentation] Anti-TRIM21 antibody seropositivity is related to B-cell abnormalities in systemic lupus erythematosus2021

Author(s)

Organizer

Data Source

[Presentation] Anti-TRIM21 antibody is associated with type I interferon and B-cell abnormalities in systemic lupus erythematosus2021

Author(s)

Organizer

Data Source

[Presentation] 全身性エリテマトーデスにおいて抗TRIM21抗体はTRIM21機能不全及びB細胞機能異常と関連する2020

Author(s)

Organizer

Data Source

[Presentation] Dysfunction of Trim21 promotes aberrant plasmablasts differentiation in B cells of systemic lupus erythematosus due to the reduction of TRIM21-mediated ubiquitylation of IRF5 protein.2019

Author(s)

Organizer

Data Source

kunishita yosuke 國下洋輔

KUNISHITA Yosuke 國下洋輔