Ito Hirotaka 伊藤博崇

Researcher Number	30863815
Other IDs
Affiliation (Current)	2025: 東京大学, 医科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京大学, 医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator ウイルス療法 / 悪性脳腫瘍 / 脳腫瘍 Except Principal Investigator がんウイルス療法 / 遺伝子治療 / 顎骨浸潤 / 口腔癌のウイルス療法

悪性脳腫瘍に対するウイルス療法における作用増強を目的とした自然免疫制御の基礎研究Principal Investigator
- Principal Investigator
  
  伊藤博崇
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo
第三世代がん治療用HSV-1を用いた口腔扁平上皮癌顎骨浸潤に対する新規治療方法の開発
- Principal Investigator
  
  内橋俊大
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka University
Therapeutic efficacy of triple-mutated oncolytic HSV-1 armed with IL-12 for bone invasion in oral squamous cell carcinoma
- Principal Investigator
  
  Uchihashi Toshihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Osaka University
Research on enhancement of therapeutic efficacy based on the kinetic analysis in oncolytic virotherapy for malignant brain tumorsPrincipal Investigator
- Principal Investigator
  
  Ito Hirotaka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokyo

All 2022 2021 2020

All Journal Article Presentation Book

[Book] CLINICAL NEUROSCIENCE2020
- Author(s)
  伊藤博崇、藤堂具紀
- Total Pages
  6
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20K09364
[Book] Medical Science Digest2020
- Author(s)
  伊藤博崇、藤堂具紀
- Total Pages
  4
- Publisher
  ニュー・サイエンス社
- Data Source
  KAKENHI-PROJECT-20K09364
[Journal Article] TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-32022
- Author(s)
  Takahashi Kazuki、Podyma-Inoue Katarzyna A.、Saito Maki、Sakakitani Shintaro、Sugauchi Akinari、Iida Keita、Iwabuchi Sadahiro、Koinuma Daizo、Kurioka Kyoko、Konishi Toru、Tanaka Susumu、Kaida Atsushi、Miura Masahiko、Hashimoto Shinichi、Okada Mariko、Uchihashi Toshihiro、Miyazono Kohei、Watabe Tetsuro
- Journal Title
  
  Cell Reports
  
  Volume: 40 Issue: 13 Pages: 111411-111411
- DOI
  10.1016/j.celrep.2022.111411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10137, KAKENHI-PROJECT-20H03851, KAKENHI-PROJECT-20K10111, KAKENHI-PROJECT-20H00513
[Journal Article] Progression of melanoma is suppressed by targeting all transforming growth factorβ isoforms with an Fc chimeric receptor.2021
- Author(s)
  Kodama S, Podyma-Inoue KΑ, Uchihashi T, Kurioka K, Takahashi H, Sugauchi A, Takahashi K, Inubushi T, Kogo M, Tanaka S, Watabe T.
- Journal Title
  
  Oncol Rep
  
  Volume: 46 Issue: 3 Pages: 197-197
- DOI
  10.3892/or.2021.8148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03851, KAKENHI-PROJECT-20K10111, KAKENHI-PROJECT-21K10137, KAKENHI-PROJECT-20H00513
[Journal Article] Oncolytic herpes virus G47Δ injected into tongue cancer swiftly traffics in lymphatics and suppresses metastasis2021
- Author(s)
  Uchihashi Toshihiro、Nakahara Hirokazu、Fukuhara Hiroshi、Iwai Miwako、Ito Hirotaka、Sugauchi Akinari、Tanaka Minoru、Kogo Mikihiko、Todo Tomoki
- Journal Title
  
  Molecular Therapy - Oncolytics
  
  Volume: 22 Pages: 388-398
- DOI
  10.1016/j.omto.2021.06.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07213, KAKENHI-PROJECT-19K10321, KAKENHI-PROJECT-21K10137, KAKENHI-PROJECT-19K09720
[Journal Article] Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses2020
- Author(s)
  Alayo Quazim A.、Ito Hirotaka、Passaro Carmela、Zdioruk Mykola、Mahmoud Ahmad Bakur、Grauwet Korneel、Zhang Xiaoli、Lawler Sean E.、Reardon David A.、Goins William F.、Fernandez Soledad、Chiocca E. Antonio、Nakashima Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 5095-5095
- DOI
  10.1038/s41598-020-61736-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09364
[Journal Article] Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus2020
- Author(s)
  Mineo Marco、Lyons Shawn M.、Zdioruk Mykola、von Spreckelsen Niklas、Ferrer-Luna Ruben、Ito Hirotaka、et al
- Journal Title
  
  Molecular Cell
  
  Volume: 78 Issue: 6 Pages: 1207-1223.e8
- DOI
  10.1016/j.molcel.2020.05.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09364
[Journal Article] Redesigned reporter gene for improved proton exchange-based molecular MRI contrast2020
- Author(s)
  Perlman Or、Ito Hirotaka、Gilad Assaf A.、McMahon Michael T.、Chiocca E. Antonio、Nakashima Hiroshi、Farrar Christian T.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 20664-20664
- DOI
  10.1038/s41598-020-77576-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09364
[Presentation] 悪性脳腫瘍モデルに対するウイルス療法における、イメージングと生体マーカーを用いた予後解析2022
- Author(s)
  伊藤博崇
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09364

1. Uchihashi Toshihiro (60757839)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 犬伏俊博 (30550941)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. IWAI Miwako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 渡部徹郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ito Hirotaka 伊藤 博崇

Research Projects

Research Products

Co-Researchers

悪性脳腫瘍に対するウイルス療法における作用増強を目的とした自然免疫制御の基礎研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

第三世代がん治療用HSV-1を用いた口腔扁平上皮癌顎骨浸潤に対する新規治療方法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic efficacy of triple-mutated oncolytic HSV-1 armed with IL-12 for bone invasion in oral squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on enhancement of therapeutic efficacy based on the kinetic analysis in oncolytic virotherapy for malignant brain tumorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] CLINICAL NEUROSCIENCE2020

Author(s)

Total Pages

Publisher

Data Source

[Book] Medical Science Digest2020

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-32022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Progression of melanoma is suppressed by targeting all transforming growth factorβ isoforms with an Fc chimeric receptor.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oncolytic herpes virus G47Δ injected into tongue cancer swiftly traffics in lymphatics and suppresses metastasis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Redesigned reporter gene for improved proton exchange-based molecular MRI contrast2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 悪性脳腫瘍モデルに対するウイルス療法における、イメージングと生体マーカーを用いた予後解析2022

Author(s)

Organizer

Data Source

Ito Hirotaka 伊藤博崇