SHIOZAWA JUN 塩澤淳

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Shiozawa Jun 塩澤淳

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Researcher Number	30868857
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2023: 順天堂大学, 医学部, 助教 2021 – 2022: 順天堂大学, 医学部, 非常勤助教 2020: 順天堂大学, 医学部, 非常勤助手
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 滑膜炎 / 早期変形性膝関節症 / ヒアルロン酸 / ヒアルロン酸分解 / 細胞外マトリックス分解 / ヒアルロン酸-アグリカンネットワーク / ヒアルロン酸代謝 / HYBID（KIAA1199/CEMIP） / ADAMTS / TMEM2 … More / HYBID / ヒアルロン酸-アグリカンネットワーク分解 / 細胞外マトリックス代謝 / 変形性膝関節症 Less

変形性膝関節症における滑膜炎発症機構解析Principal Investigator
- Principal Investigator
  
  塩澤淳
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University
Expression of hyaluronan-degrading enzymes in osteoarthritic synovium is involved in the hyaluronan degradation in synovial fluidsPrincipal Investigator
- Principal Investigator
  
  Shiozawa Jun
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Juntendo University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] 特集変形性関節症の病態に迫る-疾患修飾による治療を展望して- 早期変形性膝関節症の関節軟骨破壊機構と早期診断2023
- Author(s)
  塩澤淳、石島旨章、岡田保典
- Journal Title
  
  整形･災害外科
  
  Volume: 66 Issue: 12 Pages: 1401-1409
- DOI
  10.18888/se.0000002765
- ISSN
  0387-4095
- Year and Date
  2023-11-01
- Data Source
  KAKENHI-PROJECT-23K15750
[Journal Article] Medial meniscus extrusion is invariably observed and consistent with tibial osteophyte width in elderly populations: The Bunkyo Health Study2023
- Author(s)
  Negishi Y、Kaneko H、Aoki T、Liu L、Adili A、Arita H、Hada S、Momoeda M、Huang H、Tomura J、Wakana S、Shiozawa J、Kubota M、Someya Y、Tamura Y、Aoki S、Watada H、Kawamori R、Negishi-Koga T、Okada Y、Ishijima M
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 22805-22805
- DOI
  10.1038/s41598-023-49868-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15750, KAKENHI-PROJECT-21K09259, KAKENHI-PROJECT-22K07029, KAKENHI-PROJECT-18K09082
[Journal Article] Anterior meniscus extrusion is associated with anterior tibial osteophyte width in knee osteoarthritis ? The Bunkyo Health Study2023
- Author(s)
  Adili Arepati、Kaneko Haruka、Aoki Takako、Liu Lizu、Negishi Yoshifumi、Tomura Jun、Wakana Suguru、Momoeda Masahiro、Arita Hitoshi、Hada Shinnosuke、Shiozawa Jun、Kubota Mitsuaki、Someya Yuki、Tamura Yoshifumi、Aoki Shigeki、Watada Hirotaka、Kawamori Ryuzo、Negishi-Koga Takako、Okada Yasunori、Ishijima Muneaki
- Journal Title
  
  Osteoarthritis and Cartilage Open
  
  Volume: 5 Issue: 3 Pages: 100364-100364
- DOI
  10.1016/j.ocarto.2023.100364
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15750, KAKENHI-PROJECT-21K09259, KAKENHI-PROJECT-22K07029, KAKENHI-PROJECT-18K09082
[Journal Article] Expression and regulation of recently discovered hyaluronidases, HYBID and TMEM2, in chondrocytes from knee osteoarthritic cartilage2022
- Author(s)
  Shiozawa Jun、de Vega Susana、Yoshinaga Chiho、Ji Xang、Negishi Yoshifumi、Momoeda Masahiro、Nakamura Tomomi、Yoshida Hiroyuki、Kaneko Haruka、Ishijima Muneaki、Okada Yasunori
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 17242-17242
- DOI
  10.1038/s41598-022-22230-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09082, KAKENHI-PROJECT-22K07029, KAKENHI-PROJECT-20K18075
[Journal Article] 特集早期変形性膝関節症の診断と治療早期変形性膝関節症の関節軟骨破壊におけるヒアルロン酸分解酵素HYBID(CEMIP/KIAA1199)の意義2021
- Author(s)
  塩澤淳、石島旨章、岡田保典
- Journal Title
  
  整形･災害外科
  
  Volume: 64 Issue: 3 Pages: 253-261
- DOI
  10.18888/se.0000001645
- ISSN
  0387-4095
- Year and Date
  2021-03-01
- Data Source
  KAKENHI-PROJECT-20K18075
[Journal Article] 特集　変形性関節症の病態･治療の最新知見 Ⅰ.総論　変形性関節症における軟骨細胞外マトリックス分解の分子病態2021
- Author(s)
  塩澤淳、石島旨章、岡田保典
- Journal Title
  
  Pharma Medica
  
  Volume: 39 Issue: 6 Pages: 19-23
- DOI
  10.34449/J0001.39.06_0019-0023
- ISSN
  0289-5803
- Year and Date
  2021-06-20
- Data Source
  KAKENHI-PROJECT-20K18075
[Journal Article] Synergistic upregulation of ADAMTS4 (aggrecanase-1) by cytokines and its suppression in knee osteoarthritic synovial fibroblasts2021
- Author(s)
  Cilek Mehmet Zeynel、de Vega Susana、Shiozawa Jun、Yoshinaga Chiho、Miyamae Yuka、Chijiiwa Miyuki、Mochizuki Satsuki、Ito Masatoshi、Kaneko Haruka、Kaneko Kazuo、Ishijima Muneaki、Okada Yasunori
- Journal Title
  
  Laboratory Investigation
  
  Volume: 102 Issue: 1 Pages: 102-111
- DOI
  10.1038/s41374-021-00685-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03788, KAKENHI-PROJECT-21K06958, KAKENHI-PROJECT-20K18075, KAKENHI-PROJECT-18K09082, KAKENHI-PROJECT-22K07029
[Journal Article] Vocabulary HYBID(KIAA1199/CEMIP)2020
- Author(s)
  塩澤淳, 岡田保典
- Journal Title
  
  整形外科
  
  Volume: 71 Issue: 4 Pages: 354-354
- DOI
  10.15106/j_seikei71_354
- ISSN
  0030-5901, 2432-9444
- Year and Date
  2020-04-01
- Data Source
  KAKENHI-PROJECT-20K18075
[Journal Article] Implication of HYBID (Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization) in Hyaluronan Degradation by Synovial Fibroblasts in Patients with Knee Osteoarthritis.2020
- Author(s)
  Shiozawa J, de Vega S, Cilek MZ, Yoshinaga C, Nakamura T, Kasamatsu S, Yoshida H, Kaneko H, Ishijima M, Kaneko K, Okada Y.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 190 Issue: 5 Pages: 1046-1058
- DOI
  10.1016/j.ajpath.2020.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09083, KAKENHI-PROJECT-17K08770, KAKENHI-PROJECT-18K09082, KAKENHI-PROJECT-20K18075, KAKENHI-PROJECT-19H03788, KAKENHI-PROJECT-20K07429
[Presentation] COVID-19罹患後に発症した化膿性膝関節炎の検討2024
- Author(s)
  塩澤淳、金子晴香、羽田晋之介、吉田圭一、齋田良知、久保田光昭、石島旨章
- Organizer
  第7回東京膝をつつく会
- Invited
- Data Source
  KAKENHI-PROJECT-23K15750
[Presentation] 高齢者の変形性膝関節症に伴う滑膜炎は骨髄異常陰影と関連する -文京ヘルススタディー2023
- Author(s)
  塩澤淳、アディリアルパティ、金子晴香、小林慶司、金栄智、東村潤、若菜傑、待山祐一郎、山村拓也、久保田光昭、石島旨章
- Organizer
  第96回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-23K15750
[Presentation] 変形性膝関節症（膝OA）関節軟骨細胞でのヒアルロン酸分解酵素（HYBIDとTMEM2）の発現調節機構2023
- Author(s)
  塩澤淳、Susana de Vega、良永知穂、根岸義文、百枝雅裕、中村智美、吉田浩之、金子晴香、石島旨章、岡田保典
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K15750
[Presentation] RISK FACTORS FOR GROIN PAIN OF MALE FOOTBALLERS IN JAPAN FOOTBALL LEAGUE2023
- Author(s)
  SHIOZAWA JUN, ARITA HITOSHI, MORIO HIDENORI, IKEDA HIROSHI, MUNEAKI ISHIJIMA
- Organizer
  Isokinetic Conference 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15750
[Presentation] Expression, hyaluronan (HA)-degrading activity and regulation of HYBID and TMEM2 in human knee osteoarthritic chondrocytes2023
- Author(s)
  Jun Shiozawa, Susana de Vega, Chiho Yoshinaga, Xang Ji, Yoshifumi Negishi, Masahiro Momoeda, Tomomi Nakamura, Hiroyuki Yoshida, Haruka Kaneko, Muneaki Ishijima, Yasunori Okada
- Organizer
  第35回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] Expression and regulation of recently discovered hyaluronidases, HYBID and TMEM2 in chondrocytes from knee Osteoarthritic cartilage2023
- Author(s)
  Jun Shiozawa, Susana de Vega, Chiho Yoshinaga, Xang Ji, Yoshifumi Negishi, Masahiro Momoeda, Tomomi Nakamura, Hiroyuki Yoshida, Haruka Kaneko, Muneaki Ishijima, Yasunori Okada
- Organizer
  OARSI2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] Synovitis of osteoarthritis of the knee is associated with bone marrow abnormality in elderlies -The Bunkyo Health Study2023
- Author(s)
  Jun Shiozawa, Haruka Kaneko, Lizu Liu, Adili Arepati, Takako Aoki, Jun Tomura, Suguru Wakana, Keiji Kobayashi, Shinnosuke Hada, Youngji Kim, Yuichiro Machiyama, Takuya Yamamura, Mitsuaki Kubota, Muneaki Ishijima
- Organizer
  OARSI2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] ヒト変形性膝関節症（膝OA）関節軟骨組織における新規ヒアルロン酸分解酵素（HYBIDとTMEM2）の発現と機能解析2023
- Author(s)
  塩澤淳、Susana de Vega、良永知穂、根岸義文、百枝雅裕、中村智美、吉田浩之、金子晴香、石島旨章、岡田保典
- Organizer
  第1回日本膝関節学会
- Data Source
  KAKENHI-PROJECT-23K15750
[Presentation] 日本フットボールリーグ（ JFL ）所属サッカーチームにおけるシーズン中の股関節内転筋肉離れ発生率とそのリスク因子の検討2023
- Author(s)
  塩澤淳、有田均、森尾秀徳、池田浩、石島旨章
- Organizer
  日本スポーツ整形外科学会 2023
- Data Source
  KAKENHI-PROJECT-23K15750
[Presentation] 「私とサッカー医学」～代表・クラブチームと私～2023
- Author(s)
  塩澤淳
- Organizer
  第 13 回順天堂スポーツフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-23K15750
[Presentation] 関節軟骨破壊に関わる新規ヒアルロン酸分解酵素（HYBIDとTMEM2）の変形性関節症（OA）関節軟骨での発現調節機構2022
- Author(s)
  塩澤淳、デベガスサーナ、良永知穂、根岸義文、百枝雅裕、中村智美、吉田浩之、金子晴香、石島旨章1、岡田保典
- Organizer
  第37回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] IL-6-mediated overexpression of HYBID (hyaluronan-binding protein involved in hyaluronan depolymerization) in osteoarthritic synovium is implicated for hyaluronan degradation in synovial fluids in patients with knee osteoarthri2022
- Author(s)
  Jun Shiozawa, Susana de Vega, Mehmet Z. Cilek, Chiho Yoshinaga, Tomomi Nakamura, Shinya Kasamatsu, Hiroyuki Yoshida, Haruka Kaneko, Kazuo Kaneko, Muneaki Ishijima, Yasunori Okada
- Organizer
  OARSI2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] 新規ヒアルロニダーゼHYBID（CEMIP/KIAA1199）と近縁遺伝子TMEM2（CEMIP-2）の発現調節機構とOA関節軟骨破壊での役割2022
- Author(s)
  塩澤淳、金子晴香、石島旨章、岡田保典
- Organizer
  第12回 Orthopaedic Research Club
- Invited
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] 滑膜炎は中高年の早期変形性膝関節症の進行リスク因子である-OAIデータの縦断解析2022
- Author(s)
  塩澤淳、金子晴香、吉田圭一、小林慶司、東村潤、若菜傑、待山祐一郎、山村拓也、齋田良知、久保田光昭、石島旨章
- Organizer
  第14回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] 新規ヒアルロニダーゼHYBID及びTMEM2の膝OA関節軟骨組織における機能解析2021
- Author(s)
  塩澤淳、Susana de Vega、良永知穂、中村智美、吉田浩之、金子晴香、金子和夫、石島旨章、岡田保典
- Organizer
  第13回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] HYBIDとTMEM2の変形性膝関節症関節軟骨におけるヒアルロン酸分解活性解析と発現調節因子の検討2021
- Author(s)
  塩澤淳、Susana de Vega、良永知穂、中村智美、吉田浩之、金子晴香、石島旨章、岡田保典
- Organizer
  第53回日本結合組織学会学術集会
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] 変形性膝関節症滑膜組織でのIL-6を介したHYBID過剰発現は関節液中ヒアルロン酸低分子化に関わる2020
- Author(s)
  塩澤淳, Susana de Vega, Mehmet Z. Cilek, 良永知穂, 中村智美, 笠松慎也, 吉田浩之, 石島旨章, 金子晴香, 金子和夫, 岡田保典
- Organizer
  第12回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] 変形性膝関節症滑膜組織でのHYBID過剰発現は関節液中ヒアルロン酸 (HA) 分解に関わる2020
- Author(s)
  塩澤淳, Susana de Vega, Mehmet Z. Cilek, 良永知穂, 中村智美, 笠松慎也, 吉田浩之, 石島旨章, 金子晴香, 金子和夫, 岡田保典
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K18075
[Presentation] 変形性膝関節症（膝OA）の関節軟骨組織におけるヒアルロン酸分解酵素（HYBIDとTMEM2）の発現と発現調節機構2020
- Author(s)
  塩澤淳, de Vega Susana, 中村智美, 吉田浩之, 金子晴香, 石島旨章, 金子和夫1, 岡田保典
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K18075

1. ISHIJIMA Muneaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 金子晴香

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 岡田保典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. デベガスサーナ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIOZAWA JUN 塩澤 淳

Shiozawa Jun 塩澤 淳

Research Projects

Research Products

Co-Researchers

変形性膝関節症における滑膜炎発症機構解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Expression of hyaluronan-degrading enzymes in osteoarthritic synovium is involved in the hyaluronan degradation in synovial fluidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] 特集 変形性関節症の病態に迫る-疾患修飾による治療を展望して- 早期変形性膝関節症の関節軟骨破壊機構と早期診断2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Journal Article] Medial meniscus extrusion is invariably observed and consistent with tibial osteophyte width in elderly populations: The Bunkyo Health Study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anterior meniscus extrusion is associated with anterior tibial osteophyte width in knee osteoarthritis ? The Bunkyo Health Study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression and regulation of recently discovered hyaluronidases, HYBID and TMEM2, in chondrocytes from knee osteoarthritic cartilage2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 特集 早期変形性膝関節症の診断と治療 早期変形性膝関節症の関節軟骨破壊におけるヒアルロン酸分解酵素HYBID(CEMIP/KIAA1199)の意義2021

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Journal Article] 特集 変形性関節症の病態･治療の最新知見 Ⅰ.総論 変形性関節症における軟骨細胞外マトリックス分解の分子病態2021

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Journal Article] Synergistic upregulation of ADAMTS4 (aggrecanase-1) by cytokines and its suppression in knee osteoarthritic synovial fibroblasts2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vocabulary HYBID(KIAA1199/CEMIP)2020

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Journal Article] Implication of HYBID (Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization) in Hyaluronan Degradation by Synovial Fibroblasts in Patients with Knee Osteoarthritis.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] COVID-19罹患後に発症した化膿性膝関節炎の検討2024

Author(s)

Organizer

Data Source

[Presentation] 高齢者の変形性膝関節症に伴う滑膜炎は骨髄異常陰影と関連する -文京ヘルススタディー2023

Author(s)

Organizer

Data Source

[Presentation] 変形性膝関節症（膝OA）関節軟骨細胞でのヒアルロン酸分解酵素（HYBIDとTMEM2）の発現調節機構2023

Author(s)

SHIOZAWA JUN 塩澤淳

Shiozawa Jun 塩澤淳

[Journal Article] 特集変形性関節症の病態に迫る-疾患修飾による治療を展望して- 早期変形性膝関節症の関節軟骨破壊機構と早期診断2023

[Journal Article] 特集早期変形性膝関節症の診断と治療早期変形性膝関節症の関節軟骨破壊におけるヒアルロン酸分解酵素HYBID(CEMIP/KIAA1199)の意義2021

[Journal Article] 特集　変形性関節症の病態･治療の最新知見 Ⅰ.総論　変形性関節症における軟骨細胞外マトリックス分解の分子病態2021

[Presentation] 「私とサッカー医学」～代表・クラブチームと私～2023