Miwa Yukihiro 三輪幸裕

Researcher Number	30870430
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 特任助教
Affiliation (based on the past Project Information) *help	2020 – 2022: 慶應義塾大学, 医学部(信濃町), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator 細胞死 / 難治性網膜疾患 / Hypoxia-inducible factor / 神経変性 / 視細胞死 / 視細胞 / 網膜 / 低酸素応答 / HIF-1α / 網膜病的血管新生 … More / 網膜変性 / HIF / Hypoxia-inducible Factor / 低酸素誘導因子 Less

Controlling hypoxia-induced cell death for the treatment of retinal DegenerationPrincipal Investigator
- Principal Investigator
  
  Miwa Yukihiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Keio University

All 2022 2021 2020

All Journal Article Presentation Patent

[Journal Article] Nicotinamide Mononucleotide Protects against Retinal Dysfunction in a Murine Model of Carotid Artery Occlusion.2022
- Author(s)
  Lee D, Tomita Y, Miwa Y, Jeong H, Shinojima A, Ban N, Yamaguchi S, Nishioka K, Negishi K, Yoshino J, Kurihara T.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 23 Pages: 14711-14711
- DOI
  10.3390/ijms232314711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07377, KAKENHI-PROJECT-20K23382, KAKENHI-PROJECT-20K18393
[Journal Article] HIF Inhibition Therapy in Ocular Diseases2022
- Author(s)
  Lee Deokho、Miwa Yukihiro、Kunimi Hiromitsu、Ibuki Mari、Shoda Chiho、Nakai Ayaka、Kurihara Toshihide
- Journal Title
  
  The Keio Journal of Medicine
  
  Volume: 71 Issue: 1 Pages: 1-12
- DOI
  10.2302/kjm.2021-0004-IR
- NAID
  130008023602
- ISSN
  0022-9717, 1880-1293
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18393
[Journal Article] Nicotinamide mononucleotide prevents retinal dysfunction in a mouse model of retinal ischemia/reperfusion injury.2022
- Author(s)
  Lee D, Tomita Y, Miwa Y, Shinojima A, Ban N, Yamaguchi S, Nishioka K, Negishi K, Yoshino J, Kurihara T
- Journal Title
  
  International Journal of Molecular Sciences.
  
  Volume: 23 Issue: 19 Pages: 11228-11228
- DOI
  10.3390/ijms231911228
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07377, KAKENHI-PROJECT-20K23382, KAKENHI-PROJECT-20K18393
[Journal Article] Bilateral cataract surgery in a Japanese macaque (Macaca fuscata): A case report2021
- Author(s)
  Miwa Yukihiro、Komatsu Hiroyuki、Shinojima Ari、Oda Ayako、Inagaki Mao、Usami Kensuke、Akasaka Minori、Kobayashi Yoshitaka
- Journal Title
  
  Clinical Case Reports
  
  Volume: 9 Issue: 11
- DOI
  10.1002/ccr3.5112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18393
[Journal Article] Retinal Degeneration in a Murine Model of Retinal Ischemia by Unilateral Common Carotid Artery Occlusion2021
- Author(s)
  Lee Deokho、Nakai Ayaka、Miwa Yukihiro、Tomita Yohei、Serizawa Naho、Katada Yusaku、Hatanaka Yusuke、Tsubota Kazuo、Negishi Kazuno、Kurihara Toshihide
- Journal Title
  
  BioMed Research International
  
  Volume: 2021 Issue: 1 Pages: 1-17
- DOI
  10.1155/2021/7727648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18393
[Journal Article] Retinal dysfunction induced in a mouse model of unilateral common carotid artery occlusion2021
- Author(s)
  Lee Deokho、Jeong Heonuk、Miwa Yukihiro、Shinojima Ari、Katada Yusaku、Tsubota Kazuo、Kurihara Toshihide
- Journal Title
  
  PeerJ
  
  Volume: 9 Pages: e11665-e11665
- DOI
  10.7717/peerj.11665
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18357, KAKENHI-PROJECT-20K18393
[Journal Article] Pemafibrate Prevents Retinal Dysfunction in a Mouse Model of Unilateral Common Carotid Artery Occlusion2021
- Author(s)
  Lee Deokho、Tomita Yohei、Jeong Heonuk、Miwa Yukihiro、Tsubota Kazuo、Negishi Kazuno、Kurihara Toshihide
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 17 Pages: 9408-9408
- DOI
  10.3390/ijms22179408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18393
[Journal Article] Hypoxia-Inducible Factor Inhibitors Derived from Marine Products Suppress a Murine Model of Neovascular Retinopathy2020
- Author(s)
  Shoda Chiho、Miwa Yukihiro、Nimura Kazumi、Okamoto Kazutoshi、Yamagami Satoru、Tsubota Kazuo、Kurihara Toshihide
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 4 Pages: 1055-1055
- DOI
  10.3390/nu12041055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18393, KAKENHI-PROJECT-18K09424
[Journal Article] A Fairy Chemical Suppresses Retinal Angiogenesis as a HIF Inhibitor2020
- Author(s)
  Lee Deokho、Miwa Yukihiro、Wu Jing、Shoda Chiho、Jeong Heonuk、Kawagishi Hirokazu、Tsubota Kazuo、Kurihara Toshihide
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 10 Pages: 1405-1405
- DOI
  10.3390/biom10101405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18393, KAKENHI-PROJECT-20H05620, KAKENHI-PROJECT-18K09424
[Journal Article] A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion2020
- Author(s)
  Lee Deokho、Miwa Yukihiro、Jeong Heonuk、Ikeda Shin-ichi、Katada Yusaku、Tsubota Kazuo、Kurihara Toshihide
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: Nov 12 Issue: 165 Pages: 1-19
- DOI
  10.3791/61865
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09834, KAKENHI-PROJECT-20K18393, KAKENHI-PROJECT-18K09424
[Patent] 低酸素誘導因子阻害剤2020
- Inventor(s)
  河岸洋和、呉静、栗原俊英、三輪幸裕、正田千穂、イドクホ、坪田一男
- Industrial Property Rights Holder
  河岸洋和、呉静、栗原俊英、三輪幸裕、正田千穂、イドクホ、坪田一男
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-20K18393
[Presentation] HIF阻害剤ハロフジノンによるマウス網膜光障害モデルに対する治療的効果2022
- Author(s)
  三輪幸裕
- Organizer
  第126回　日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K18393
[Presentation] 魚類由来HIF阻害物質による網膜病的血管新生・神経変性に対する治療的効果2022
- Author(s)
  三輪幸裕
- Organizer
  第41回比較眼科学会年次大会
- Data Source
  KAKENHI-PROJECT-20K18393
[Presentation] Protective effects of a HIF Inhibitor halofuginone on light-induced retinal damage via suppression of HIF/BNIP3 axis2022
- Author(s)
  三輪幸裕
- Organizer
  The Association for Research in Vision and Ophthalmology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18393
[Presentation] HIF阻害剤ハロフジノンのマウス網膜変性モデルに対する治療的効果とその分子機序に関する検討2022
- Author(s)
  三輪幸裕
- Organizer
  第30回中部小動物臨床研究会
- Data Source
  KAKENHI-PROJECT-20K18393
[Presentation] 緑内障チューブシャント術時の抗線維化処置に関する検討2021
- Author(s)
  三輪幸裕
- Organizer
  第40回比較眼科学会年次大会
- Data Source
  KAKENHI-PROJECT-20K18393

1. IKEDA Shin-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. YAMAGUCHI Shintaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. ジョンホヌク

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miwa Yukihiro 三輪 幸裕

Research Projects

Research Products

Co-Researchers

Controlling hypoxia-induced cell death for the treatment of retinal DegenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Nicotinamide Mononucleotide Protects against Retinal Dysfunction in a Murine Model of Carotid Artery Occlusion.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HIF Inhibition Therapy in Ocular Diseases2022

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Nicotinamide mononucleotide prevents retinal dysfunction in a mouse model of retinal ischemia/reperfusion injury.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bilateral cataract surgery in a Japanese macaque (Macaca fuscata): A case report2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Retinal Degeneration in a Murine Model of Retinal Ischemia by Unilateral Common Carotid Artery Occlusion2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Retinal dysfunction induced in a mouse model of unilateral common carotid artery occlusion2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pemafibrate Prevents Retinal Dysfunction in a Mouse Model of Unilateral Common Carotid Artery Occlusion2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypoxia-Inducible Factor Inhibitors Derived from Marine Products Suppress a Murine Model of Neovascular Retinopathy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Fairy Chemical Suppresses Retinal Angiogenesis as a HIF Inhibitor2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion2020

Author(s)

Journal Title

DOI

Data Source

[Patent] 低酸素誘導因子阻害剤2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Acquisition Date

Data Source

[Presentation] HIF阻害剤ハロフジノンによるマウス網膜光障害モデルに対する治療的効果2022

Author(s)

Organizer

Data Source

[Presentation] 魚類由来HIF阻害物質による網膜病的血管新生・神経変性に対する治療的効果2022

Author(s)

Organizer

Data Source

[Presentation] Protective effects of a HIF Inhibitor halofuginone on light-induced retinal damage via suppression of HIF/BNIP3 axis2022

Author(s)

Miwa Yukihiro 三輪幸裕