Otomo Akihiro 大友章裕

Researcher Number	30886560
Other IDs
Affiliation (Current)	2025: 京都大学, 理学研究科, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 分子科学研究所, 生命・錯体分子科学研究領域, 助教
Review Section/Research Field	Principal Investigator Basic Section 13040:Biophysics, chemical physics and soft matter physics-related / Basic Section 43040:Biophysics-related / Basic Section 43040:Biophysics-related
Keywords	Principal Investigator 分子モーター / １分子計測 / V-ATPase / ナトリウムポンプ / エネルギー変換 / ATP合成酵素 / ナトリウムイオンポンプ / １分子観察

Research Projects
(3 results)
Research Products
(21 results)

V-ATPaseのナトリウム駆動力による回転１分子観察とイオン/ATP共役比の改変Principal Investigator
- Principal Investigator
  
  大友章裕
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 13040:Biophysics, chemical physics and soft matter physics-related
- Research Institution
  Institute for Molecular Science
Functional and Structural Relationship of V-ATPase Revealed by Single-Molecule ObservationPrincipal Investigator
- Principal Investigator
  
  Otomo Akihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Institute for Molecular Science
Elucidation of the rotation mechanism of V-ATPase by electrochemical potentialPrincipal Investigator
- Principal Investigator
  
  大友章裕
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Institute for Molecular Science

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Sub-Tip-Radius Near-Field Interactions in Nano-FTIR Vibrational Spectroscopy on Single Proteins2024
- Author(s)
  Nishida Jun、Otomo Akihiro、Koitaya Takanori、Shiotari Akitoshi、Minato Taketoshi、Iino Ryota、Kumagai Takashi
- Journal Title
  
  Nano Letters
  
  Volume: 24 Issue: 3 Pages: 836-843
- DOI
  10.1021/acs.nanolett.3c03479
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15060, KAKENHI-PROJECT-19K24684
[Journal Article] Protein dynamics of a light-driven Na<sup>+</sup> pump rhodopsin probed using a tryptophan residue near the retinal chromophore2023
- Author(s)
  Otomo Akihiro、Mizuno Misao、Inoue Keiichi、Kandori Hideki、Mizutani Yasuhisa
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 20 Issue: Supplemental Pages: n/a
- DOI
  10.2142/biophysico.bppb-v20.s016
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15060, KAKENHI-PLANNED-20H05758, KAKENHI-PROJECT-20H02693, KAKENHI-PROJECT-20K21383, KAKENHI-PROJECT-21H04969, KAKENHI-PROJECT-23K21092
[Journal Article] Direct observation of stepping rotation of V-ATPase reveals rigid component in coupling between Vo and V1 motors2022
- Author(s)
  Otomo Akihiro、Iida Tatsuya、Okuni Yasuko、Ueno Hiroshi、Murata Takeshi、Iino Ryota
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 42
- DOI
  10.1073/pnas.2210204119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15060, KAKENHI-PLANNED-18H05424, KAKENHI-PUBLICLY-21H00388
[Presentation] 腸球菌由来V-ATPaseはナトリウムイオン駆動力でATPを合成する2023
- Author(s)
  大友章裕, Lucy Gao Hui Zhu, 山本真由子, 大国泰子, 飯野亮太
- Organizer
  2023年度生物物理学会中部支部討論会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] 腸球菌由来V-ATPaseはナトリウムイオン駆動力でATPを合成する2023
- Author(s)
  大友章裕, Lucy Gao Hui Zhu, 山本真由子, 大国泰子, 原島崇徳, 飯野亮太
- Organizer
  日本生体エネルギー研究会第49回討論会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] 腸球菌由来V-ATPaseはナトリウムイオン駆動力でATPを合成する2023
- Author(s)
  大友章裕, Lucy Gao Hui Zhu, 原島崇徳, 飯野亮太
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] １分子散乱イメージングによる回転分子モーター V-ATPaseの回転機構の解明2023
- Author(s)
  大友章裕
- Organizer
  第9回バイオダイナミクス研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] Sodium motive force-driven ATP synthesis of EhV-ATPase2023
- Author(s)
  大友章裕, Lucy Gao Hui Zhu, 山本真由子, 大国泰子, 飯野亮太
- Organizer
  第12回分子モーター討論会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] Integrated research on rotary V-ATPase approached by single-molecule observation, biochemical assay, and protein engineering2022
- Author(s)
  Akihiro Otomo, Ryota Iino
- Organizer
  第60回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] Single-molecule analysis and engineering of Na+-pumping V-ATPase2022
- Author(s)
  Akihiro Otomo, Ryota Iino
- Organizer
  2022 East Asian Single-Molecule Biophysics Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] 多重配列アライメントとスクリーニング法による新規モータータンパク質の創生2022
- Author(s)
  大友章裕, Song Chihong、Raymo, N. Burton-Smith, 富井健太郎, 村田和義, 小嶋誠司, 飯野亮太
- Organizer
  令和4年度日本生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] 生体内エネルギー変換機構の解明に向けた回転モータータンパク質改変体の創生2022
- Author(s)
  大友　章裕、原島　崇徳、飯野　亮太
- Organizer
  日本生体エネルギー研究会第48回討論会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] Construction of hybrid molecular motor by engineering kinesin-1 with synthetic linker2022
- Author(s)
  Jakia Jannat Keya, Akasit Visootsat, Takeda Kimitoshi, Akihiro Otomo, Sanghun Han, Kazushi Kinbara, Ryota Iino
- Organizer
  令和3年度日本生物物理学会中部支部会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] V-ATPaseのイオン結合部位を改造した新規モータータンパク質作製の取り組み2022
- Author(s)
  大友章裕、大国泰子、今弥生、飯野亮太
- Organizer
  令和3年度日本生物物理学会中部支部会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] Single-molecule analysis and engineering of rotary V-ATPase2022
- Author(s)
  Akihiro Otomo, Tatsuya Iida, Hiroshi Ueno, Takeshi Murata, Ryota Iino
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] Enterococcus hirae由来V-ATPaseは”硬い”カップリングで対称性の不一致を気にせず回転する2021
- Author(s)
  大友章裕、飯田龍也、上野博史、村田武士、飯野亮太
- Organizer
  第47回日本生体エネルギー研究会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] Na+輸送性V-ATPaseのイオン輸送と共役した回転ステップの１分子観察2021
- Author(s)
  大友章裕, 飯田龍也，上野博史，村田武士，飯野亮太
- Organizer
  令和2年度生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-20J01316
[Presentation] Engineering of hybrid kinesin-1 dimer with synthetic linker by tuning the neck linker length2021
- Author(s)
  Jakia Jannat Keya, Akasit Visootsat, Akihiro Otomo, Sanghun Han, Kazushi Kinbara, Ryota Iino
- Organizer
  第59回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] Direct Observation of Stepping Rotation of V-ATPase Reveals Rigid and Non-integer Coupling between Vo and V1 Motors2021
- Author(s)
  大友章裕、飯田龍也、上野博史、村田武士、飯野亮太
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K15060
[Presentation] Enterococcus hirae由来V-ATPaseのナトリウムイオン濃度に依存した回転運動の１分子解析2020
- Author(s)
  大友章裕, 飯田龍也，上野博史，村田武士，飯野亮太
- Organizer
  第10回分子モーター討論会
- Data Source
  KAKENHI-PROJECT-20J01316
[Presentation] Single-molecule analysis of rotation of Enterococcus hirae V-ATPase depending on sodium ion concentration2020
- Author(s)
  大友章裕, 飯田龍也，上野博史，村田武士，飯野亮太
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20J01316

Otomo Akihiro 大友 章裕

Research Projects

Research Products

V-ATPaseのナトリウム駆動力による回転１分子観察とイオン/ATP共役比の改変Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional and Structural Relationship of V-ATPase Revealed by Single-Molecule ObservationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the rotation mechanism of V-ATPase by electrochemical potentialPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Sub-Tip-Radius Near-Field Interactions in Nano-FTIR Vibrational Spectroscopy on Single Proteins2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein dynamics of a light-driven Na<sup>+</sup> pump rhodopsin probed using a tryptophan residue near the retinal chromophore2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Direct observation of stepping rotation of V-ATPase reveals rigid component in coupling between Vo and V1 motors2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] 腸球菌由来V-ATPaseはナトリウムイオン駆動力でATPを合成する2023

Author(s)

Organizer

Data Source

[Presentation] 腸球菌由来V-ATPaseはナトリウムイオン駆動力でATPを合成する2023

Author(s)

Organizer

Data Source

[Presentation] 腸球菌由来V-ATPaseはナトリウムイオン駆動力でATPを合成する2023

Author(s)

Organizer

Data Source

[Presentation] １分子散乱イメージングによる回転分子モーター V-ATPaseの回転機構の解明2023

Author(s)

Organizer

Data Source

[Presentation] Sodium motive force-driven ATP synthesis of EhV-ATPase2023

Author(s)

Organizer

Data Source

[Presentation] Integrated research on rotary V-ATPase approached by single-molecule observation, biochemical assay, and protein engineering2022

Author(s)

Organizer

Data Source

[Presentation] Single-molecule analysis and engineering of Na+-pumping V-ATPase2022

Author(s)

Organizer

Data Source

[Presentation] 多重配列アライメントとスクリーニング法による新規モータータンパク質の創生2022

Author(s)

Organizer

Data Source

[Presentation] 生体内エネルギー変換機構の解明に向けた回転モータータンパク質改変体の創生2022

Author(s)

Organizer

Data Source

[Presentation] Construction of hybrid molecular motor by engineering kinesin-1 with synthetic linker2022

Author(s)

Organizer

Data Source

[Presentation] V-ATPaseのイオン結合部位を改造した新規モータータンパク質作製の取り組み2022

Author(s)

Otomo Akihiro 大友章裕