Mukai Yasutaka 向井康敬

Researcher Number	30908124
Other IDs	https://orcid.org/0000-0002-0185-2040
Affiliation (Current)	2025: 名古屋大学, 理学研究科, 助教
Affiliation (based on the past Project Information) *help	2024: 名古屋市立大学, 医薬学総合研究院(薬学), 助教 2023: 北海道大学, 医学研究院, 特別研究員(PD) 2021 – 2023: 名古屋大学, 環境医学研究所, 特任助教 2021: 名古屋大学, 環境医学研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 46030:Function of nervous system-related / 0704:Neuroscience, brain sciences, and related fields Except Principal Investigator Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator 神経科学 / 青斑核ノルアドレナリン神経 / 神経修飾 / EP3受容体 / 神経活動調節 / カルシウムイメージング / 睡眠覚醒 / うつ様行動 / ストレス / プロスタグランジンE2 … More / 青班核ノルアドレナリン神経 / 生理学 / 哺乳類 / 行動 / あくび / 光遺伝学 / 陰イオンチャネルロドプシン / 生理活性物質 / ファイバーフォトメトリー / ノルアドレナリン / 青斑核 / 疾病応答 / 尾懸垂試験 / 神経活動修飾 / うつ様状態 / 神経活動 / 鬱様行動 … More Except Principal Investigator パッチクランプ法 / 光遺伝学 / 唾液 / 麻酔薬 / 上唾液核ニューロン / 舌 / 涙腺 / オレキシン / 味覚 / 顎下腺・舌下腺 / 視床下部外側野 / 上唾液核 Less

Unraveling the molecular basis of "yawning" in the brainPrincipal Investigator
- Principal Investigator
  
  向井康敬
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Nagoya City University
Physiological role of sustained suppression of neural activity by prostaglandin E2Principal Investigator
- Principal Investigator
  
  Mukai Yasutaka
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Hokkaido University
  Nagoya University
Saliva for tasting and eating food: Its central nervous mechanism
- Principal Investigator
  
  Mitoh Yoshihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Okayama University
Physiological role of long-lasting suppression of noradrenergic neurons in the locus coeruleus induced by prostaglandin E2Principal Investigator
- Principal Investigator
  
  Mukai Yasutaka
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0704:Neuroscience, brain sciences, and related fields
- Research Institution
  Nagoya University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors2023
- Author(s)
  Li Wan-Ru、Nakano Takashi、Mizutani Kohta、Matsubara Takanori、Kawatani Masahiro、Mukai Yasutaka、Danjo Teruko、Ito Hikaru、Aizawa Hidenori、Yamanaka Akihiro、Petersen Carl C.H.、Yoshimoto Junichiro、Yamashita Takayuki
- Journal Title
  
  Current Biology
  
  Volume: 33 Issue: 16 Pages: 3436-3451
- DOI
  10.1016/j.cub.2023.07.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18256, KAKENHI-PROJECT-23KJ0002, KAKENHI-PROJECT-21K05998, KAKENHI-PROJECT-21K19315, KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-21H02581
[Journal Article] Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy2023
- Author(s)
  Ito Hiroto、Fukatsu Noriaki、Rahaman Sheikh Mizanur、Mukai Yasutaka、Izawa Shuntaro、Ono Daisuke、Kilduff Thomas S.、Yamanaka Akihiro
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 41
- DOI
  10.1073/pnas.2301951120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KJ0005, KAKENHI-PROJECT-23KJ0002, KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-23K27275
[Journal Article] Prostaglandin E2 Induces Long-Lasting Inhibition of Noradrenergic Neurons in the Locus Coeruleus and Moderates the Behavioral Response to Stressors2023
- Author(s)
  Mukai Yasutaka、Okubo Tatsuo S.、Lazarus Michael、Ono Daisuke、Tanaka Kenji F.、Yamanaka Akihiro
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 43 Issue: 47 Pages: 7982-7999
- DOI
  10.1523/jneurosci.0353-23.2023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KJ0002, KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-23K21394
[Journal Article] Cre-dependent ACR2-expressing reporter mouse strain for efficient long-lasting inhibition of neuronal activity.2023
- Author(s)
  Mukai Y, Li Y, Nakamura A, Fukatsu N, Iijima D, Abe M, Sakimura K, Itoi K, Yamanaka A.
- Journal Title
  
  Sci Rep.
  
  Volume: 13(1) Issue: 1 Pages: 3966-3966
- DOI
  10.1038/s41598-023-30907-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08563, KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-21K20688
[Journal Article] Functional roles of REM sleep2023
- Author(s)
  Mukai Yasutaka、Yamanaka Akihiro
- Journal Title
  
  Neuroscience Research
  
  Volume: 189 Pages: 44-53
- DOI
  10.1016/j.neures.2022.12.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-21K20688
[Journal Article] The oxytocin system regulates tearing2022
- Author(s)
  Nakamura Shigeru、Imada Toshihiro、Jin Kai、Shibuya Michiko、Sakaguchi Hisayo、Izumiseki Fumiya、Tanaka Kenji F、Mimura Masaru、Nishimori Kastuhiro、Kambara Natsumi、Hirayama Nozomi、Kamimura Itsuka、Nomoto Kensaku、Mogi Kazutaka、Kikusui Takefumi、Mukai Yasutaka、Yamanaka Akihiro、Tsubota Kazuo
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2022.03.08.483433
- Open Access
- Data Source
  KAKENHI-PROJECT-21K20688
[Journal Article] Primary motor cortex drives expressive facial movements related to reward processing in mice2022
- Author(s)
  Li Wanru、Nakano Takashi、Mizutani Kohta、Kawatani Masahiro、Matsubara Takanori、Danjo Teruko、Mukai Yasutaka、Yamanaka Akihiro、Ito Hikaru、Aizawa Hidenori、Petersen Carl C. H.、Yoshimoto Junichiro、Yamashita Takayuki
- Journal Title
  
  bioRxiv
  
  Volume: - Pages: 1-62
- DOI
  10.1101/2022.10.28.514159
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-21K20688, KAKENHI-PUBLICLY-21H00215, KAKENHI-PUBLICLY-23H04685, KAKENHI-PROJECT-23K24200
[Journal Article] Functional Interaction Between GABAergic Neurons in the Ventral Tegmental Area and Serotonergic Neurons in the Dorsal Raphe Nucleus2022
- Author(s)
  Rahaman Sheikh Mizanur、Chowdhury Srikanta、Mukai Yasutaka、Ono Daisuke、Yamaguchi Hiroshi、Yamanaka Akihiro
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 808754-808754
- DOI
  10.3389/fnins.2022.877054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15225, KAKENHI-PROJECT-20KK0177, KAKENHI-PROJECT-21H02526, KAKENHI-PROJECT-22KF0166, KAKENHI-PROJECT-21K19255, KAKENHI-PROJECT-21K20688, KAKENHI-PUBLICLY-21H00307, KAKENHI-PUBLICLY-21H00422
[Presentation] Prostaglandin E2 induces sustained suppression of noradrenergic neurons in the locus coeruleus to moderate stress response2024
- Author(s)
  向井康敬、大久保達夫、Michael Lazarus、小野大輔、田中謙二、山中章弘
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K15225
[Presentation] Generation and in vivo functional evaluation of novel ACR2 reporter mice2023
- Author(s)
  中村明代、向井康敬、李妍、深津紀暁、飯嶋大右、阿部学、﨑村健司、井樋慶一、山中章弘
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-22K15225
[Presentation] Identification of substances that modulate the activity of noradrenergic neurons in the locus coeruleus2023
- Author(s)
  向井康敬、Michael Lazarus、永井健治、田中謙二、山中章弘
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-22K15225
[Presentation] Generation and in vivo functional evaluation of novel ACR2 reporter mice2023
- Author(s)
  中村明代、向井康敬、李妍、深津紀暁、飯嶋大右、阿部学、﨑村健司、井樋慶一、山中章弘
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K20688
[Presentation] Long-term in vivo calcium imaging in orexin neurons with optogenetic activation of dopamine neurons2023
- Author(s)
  飯嶋大右、向井康敬、山中章弘
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K20688
[Presentation] Long-term in vivo calcium imaging in orexin neurons with optogenetic activation of dopamine neurons2023
- Author(s)
  飯嶋大右、向井康敬、山中章弘
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-22K15225
[Presentation] 社会的敗北ストレスによって誘導される行動変容における前頭前皮質オキシトシン受容体発現ニューロンの生理機能2022
- Author(s)
  犬束歩、向井康敬、吉田匡秀、高柳友紀、山中章弘、尾仲達史
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-22K15225
[Presentation] オレキシン神経の活動記録と睡眠中の活動の役割2022
- Author(s)
  伊藤洋人、深津紀暁、ラハマン・セイク・ミザン、伊澤俊太郎、向井康敬、小野大輔、Kilduff Thomas、山中章弘
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-22K15225
[Presentation] 社会的敗北ストレスによって誘導される行動変容における前頭前皮質オキシトシン受容体発現ニューロンの生理機能2022
- Author(s)
  犬束歩、向井康敬、吉田匡秀、高柳友紀、山中章弘、尾仲達史
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-21K20688
[Presentation] 青斑核ノルアドレナリン神経活動を持続的に抑制するプロスタグランジンE2の生理機能2022
- Author(s)
  向井康敬、ラザルス・ミハエル、永井健治、田中謙二、山中章弘
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-21K20688
[Presentation] 青斑核ノルアドレナリン神経活動を持続的に抑制するプロスタグランジンE2の生理機能2022
- Author(s)
  向井康敬、ラザルス・ミハエル、永井健治、田中謙二、山中章弘
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-22K15225
[Presentation] オレキシン神経の活動記録と睡眠中の活動の役割2022
- Author(s)
  伊藤洋人、深津紀暁、ラハマン・セイク・ミザン、伊澤俊太郎、向井康敬、小野大輔、Kilduff Thomas、山中章弘
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-21K20688
[Presentation] 光遺伝学を用いてドーパミン神経を活性化させた時のオレキシン神経の長時間in vivoカルシウムイメージング2022
- Author(s)
  飯嶋大右、向井康敬、山中章弘
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-22K15225
[Presentation] 青斑核ノルアドレナリン神経を持続的に抑制するプロスタグランジンE2の生理的役割について2022
- Author(s)
  向井康敬, ラザルス・ミハエル, 永井健治, 田中謙二, 山中章弘
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K20688
[Presentation] 光遺伝学を用いてドーパミン神経を活性化させた時のオレキシン神経の長時間in vivoカルシウムイメージング2022
- Author(s)
  飯嶋大右、向井康敬、山中章弘
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-21K20688
[Presentation] プロスタグランジンE2による、青斑核ノルアドレナリン神経活動の長期的な調節機構2021
- Author(s)
  向井康敬
- Organizer
  第4回名古屋リズム研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K20688
[Presentation] 青斑核ノルアドレナリン神経におけるプロスタグランジンE2の生理機能の探索2021
- Author(s)
  向井康敬, ラザルス・ミハエル, 永井健治, 田中謙二, 山中章弘
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K20688
[Presentation] 特定神経の活動を調節する物質のスクリーニングと、それを用いた生理機能の解明2021
- Author(s)
  向井康敬, 永山綾子, 井樋慶一, 山中章弘
- Organizer
  日本睡眠学会第46回定期学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K20688

1. Mitoh Yoshihiro (20240872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 相澤秀紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 井樋慶一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mukai Yasutaka 向井 康敬

Research Projects

Research Products

Co-Researchers

Unraveling the molecular basis of "yawning" in the brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological role of sustained suppression of neural activity by prostaglandin E2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Saliva for tasting and eating food: Its central nervous mechanism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological role of long-lasting suppression of noradrenergic neurons in the locus coeruleus induced by prostaglandin E2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prostaglandin E2 Induces Long-Lasting Inhibition of Noradrenergic Neurons in the Locus Coeruleus and Moderates the Behavioral Response to Stressors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cre-dependent ACR2-expressing reporter mouse strain for efficient long-lasting inhibition of neuronal activity.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional roles of REM sleep2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The oxytocin system regulates tearing2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Primary motor cortex drives expressive facial movements related to reward processing in mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional Interaction Between GABAergic Neurons in the Ventral Tegmental Area and Serotonergic Neurons in the Dorsal Raphe Nucleus2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Prostaglandin E2 induces sustained suppression of noradrenergic neurons in the locus coeruleus to moderate stress response2024

Author(s)

Organizer

Data Source

[Presentation] Generation and in vivo functional evaluation of novel ACR2 reporter mice2023

Author(s)

Organizer

Data Source

[Presentation] Identification of substances that modulate the activity of noradrenergic neurons in the locus coeruleus2023

Author(s)

Organizer

Data Source

Mukai Yasutaka 向井康敬