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Koutarou Nishimura  西村 耕太郎

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Nishimura Koutarou  西村 耕太郎

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Researcher Number 30909982
Affiliation (Current) 2025: 大阪大学, 大学院生命機能研究科, 准教授
2025: 公益財団法人神戸医療産業都市推進機構, その他部局等, 研究員(上席・主任研究員クラス)
Affiliation (based on the past Project Information) *help 2022 – 2023: 公益財団法人神戸医療産業都市推進機構, その他部局等, 研究員(上席・主任研究員クラス)
2021 – 2022: 横浜市立大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / 0904:Internal medicine of the bio-information integration and related fields
Keywords
Principal Investigator
エピジェネティクス / CRISPRスクリーニング / 造血幹細胞分化 / p53変異体 / TP53 / AML / 単核貪食細胞分化 / ビオチン化近位標識 / p53 / 普遍的細胞分化増殖停止 … More / マスター転写因子 / エピゲノム / 転写因子 / 細胞分化 Less
  • Research Projects

    (3 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (3 People)
  •  Innovation of the novel therapeutic strategies against p53 mutated acute myeloid leukemia.Principal Investigator

    • Principal Investigator
      西村 耕太郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Foundation for Biomedical Research and Innovation at Kobe
  •  単核貪食細胞分化におけるlncRNAを介したIrf8エンハンサー制御機構の解析Principal Investigator

    • Principal Investigator
      西村 耕太郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Yokohama City University
  •  Decoding the universal cell differentiation mechanisms.Principal Investigator

    • Principal Investigator
      Nishimura Koutarou
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0904:Internal medicine of the bio-information integration and related fields
    • Research Institution
      Foundation for Biomedical Research and Innovation at Kobe
      Yokohama City University

All 2024 2023 2022

All Journal Article Presentation

  • [Journal Article] The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis2023

    • Author(s)
      Ikeda N, Kubota H, Suzuki R, Morita M, Yoshimura A, Osada Y, Kishida K, Kitamura D, Iwata A, Yotsumoto S, Kurotaki D, Nishimura K, Nishiyama A, Tamura T, Kamatani T, Tsunoda T, Murakawa M, Asahina Y, Hayashi Y, Harada H, Harada Y, Yokota A, Hirai H, Seki T, Kuwahara M, Yamashita M, Shichino S, Tanaka M, Asano K.
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 3 Pages: 112165-112165

    • DOI

      10.1016/j.celrep.2023.112165

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07977, KAKENHI-PROJECT-22K19462, KAKENHI-PROJECT-21K15421, KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-21H05029, KAKENHI-PROJECT-21K20936, KAKENHI-PROJECT-23K24166, KAKENHI-PROJECT-21K08205, KAKENHI-PROJECT-21K08379, KAKENHI-PROJECT-21K19476, KAKENHI-PROJECT-19H04355, KAKENHI-PROJECT-21H02954, KAKENHI-PROJECT-21H02956, KAKENHI-PROJECT-23K24315
  • [Journal Article] Extracellular vesicle-mediated remodeling of the bone marrow microenvironment in myeloid malignancies2023

    • Author(s)
      Hayashi Yasutaka、Nishimura Koutarou、Tanaka Atsushi、Inoue Daichi
    • Journal Title

      International Journal of Hematology

      Volume: 117 Issue: 6 Pages: 821-829

    • DOI

      10.1007/s12185-023-03587-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20J01911, KAKENHI-PROJECT-20K21622, KAKENHI-PROJECT-21K20936, KAKENHI-PROJECT-21K16258
  • [Journal Article] Dysregulated minor intron splicing in cancer.2022

    • Author(s)
      Nishimura K*, Yamazaki H*, Zang W, Inoue D.
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 9 Pages: 2934-2942

    • DOI

      10.1111/cas.15476

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08432, KAKENHI-PROJECT-22K19475, KAKENHI-PROJECT-21K20936, KAKENHI-PROJECT-20H03717
  • [Presentation] クロマチンリモデリング因子BRD9の造血における生物学的意義2024

    • Author(s)
      西村 耕太郎
    • Organizer
      第28回造血器腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-23K07824
  • [Presentation] Revealing unrecognized the gain-of-function of TP53 mutations in the determination of HSC fate2023

    • Author(s)
      西村 耕太郎
    • Organizer
      第8回神戸横浜熊本交流会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K07824
  • [Presentation] Revealing Unrecognized Gain-of-Function of TP53 Mutations in the Determinati on of HSC Fate2023

    • Author(s)
      Koutarou Nishimura, Weijia Zang, June Takeda, Yui Koike, Hiromi Ito, Hiromi Yamazaki, Seishi Ogawa and Daichi Inoue
    • Organizer
      第85回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K20936
  • [Presentation] Dissecting the unrecognized roles of mutations in TP53 “Guardian of the Genome”2023

    • Author(s)
      Koutarou Nishimura
    • Organizer
      第82回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K20936
  • [Presentation] p53変異体を標的とする新規治療戦略の開発2023

    • Author(s)
      西村耕太郎、井上大地
    • Organizer
      第27回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K20936
  • [Presentation] Uncovering the unrecognized roles on cell fate and leukemogenesis of p53 mutations2023

    • Author(s)
      西村 耕太郎
    • Organizer
      第20回幹細胞シンポジウム
    • Data Source
      KAKENHI-PROJECT-23K07824
  • [Presentation] Uncovering the unrecognized roles on cell fate and leukemogenesis of p53 mutations2023

    • Author(s)
      Koutarou Nishimura, Weijia Zang, Hiromi Ito, Yui Koike, Hiromi Yamazaki, Daichi Inoue
    • Organizer
      The 20th Stem Cell Research Symposium
    • Data Source
      KAKENHI-PROJECT-21K20936
  • [Presentation] 新規p53変異白血病モデルが明らかにする癌代謝変容の新局面2023

    • Author(s)
      西村 耕太郎
    • Organizer
      第85回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K07824
  • [Presentation] ゲノムの守護神p53の変異がもたらす新たな変容機構2023

    • Author(s)
      西村 耕太郎
    • Organizer
      第82回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K07824
  • [Presentation] 単核貪食細胞分化におけるIrf8エンハンサー群の動的制御機構の解明2022

    • Author(s)
      西村耕太郎
    • Organizer
      第26回造血器腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-21K20936
  • 1.  ASAHINA Yasuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  村川 美也子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  山嵜 博未
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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