HAYAISHI Osamu 早石修

Researcher Number	40025507
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011: 大阪バイオサイエンス研究所, 分子行動生物学部門, 教授 2010: (財)大阪バイオサイエンス研究所, 分子行動生物学部門 2007 – 2010: Osaka Bioscience Institute, Department of Molecular Behavioral Biology, Researcher 2008: (財)大阪バイオサイエンス研究所, 分子行動生物学部門, 研究員 2008: 分子行動生物学部門, 研究員 … More
Review Section/Research Field	Principal Investigator General medical chemistry / Neurochemistry/Neuropharmacology / Pathological medical chemistry / 寄生虫学(含医用動物学) / Functional biochemistry / Neurochemistry/Neuropharmacology Except Principal Investigator General medical chemistry / Pathological medical chemistry / 睡眠学 / Functional biochemistry … More
Keywords	Principal Investigator 睡眠 / プロスタグランジン / Wakefulness / プロスタグランジンD_2 / プロスタグランジンE_2 / 睡眠・覚醒 / 覚醒 / Sleep / Prostaglandin D synthase / 脈絡叢 … More Except Principal Investigator 睡眠 / Sleep / プロスタグランジン / プロスタグランジンD合成酵素 / 覚醒 / アデノシン / トランスジェニックマウス / Adenosine / 脳脊髄液 / プロスタグランジンD_2 / Knockout mice / Wakefulness / プロスタグランジンD2 / ノックアウトマウス / Prostaglandin D2 / Caffeine / 嗅結節 / 側坐核 / リポカリン / knockout mice / Prostaglandin D_2 / Prostaglandin D synthase / A2A receptor / A1 receptor / PGF合成酵素 / アルド・ケト還元酵素 / sleep / 遺伝子ノックアウト / クモ膜 / prostaglandin D2 / 多機能酵素 / A_2-adenosine receptor / 吻側前脳基底部 / Th2サイトカイン / Wake / gene-engineering / X-ray crystallographic analysis / A_<2A>受容体 / ラット / イボテン酸 / Th2 cytokine / transgenic mouse / Prostaglandin / X線結晶解析 / 受容体 / transgenic mice / Olfactory tubercle / 肥満細胞 / eosinophil / 活性部位 / Accumbens nucleus / 遺伝子工学 / カフェイン / 好酸球 / Hiatamine H1 receptor / Rostral basal forebrain / A_2アデノシン受容体 / オレキシン / グラフィックス・ソフトウェア / allergy / 昏睡 / X-ray'crystallography / 酵素学 / PGF2α / セロトニン / グルタチオン / 再設計 / 間質細胞 / Evolution / 精製 / PGF_2α / 脳血流 / Prediction of three dimensional structure / 局所的RNAi干渉法 / hypoxia / 二次構造予測 / 三次元構造予測 / 9α・11βーPGF_2 / 子宮 / Cre/loxPシステム / トランスポーター / A_1受容体 / Aequorin / 免疫抑制 / Prediction of secondary structure / receptor / 金属イオン / loxPシステム / 酵素阻害剤 / 構造 / Ligand / 神経回路網 / mast cell / ヒスタミン / マウス / 低酸素 / Subarachnoid space / 分子モデリング / 9alpha, 11beta -PGF_2 / システイン / アゴニスト / Calcium-binding protein / ベータートレース / caffeine / enzyme inhibitor / wakefulness / prostaglandin (PG) F / 9α,11βーPGF_2 / マラリア / クリスタリン / 不眠 / Nucleus accumbens / Membrane-bound enzyme / adenosine / アフリカ睡眠病 / 局所的RNA干渉 / 多連微小ピペット / Basal forebrain / 対角帯 / GC-MS / 遺伝子操作 / Inorganic selenium compounds / プロスタグランジン(PG)F / Prostagladin synthase / 光親和ラベル / VLPO / PGF Synthase / セレン / 酵素精製 / 酵素 / 前脳基底部 / クモ膜下腔 / A_<2A> receptor / Isozyme / 進化 / PGE synthase / 精液 / 微量持続注入 / アデノシンA_2A 受容体 / Model building / エクオリン / lung / テレメトリー / prostaglandin synthase / 徐波睡眠 / NO / Metal ions / プロスタグランジンF / 膜結合 / プロトゾア / 結晶構造解析 / Transgenic mice / ロイコトリエン / ムシモール / knockout mouse / マイクロダイアリシス / グリシン / ELISA / リガンド / プロスタグランジンE_2 / Cerebrospinal fluid / リポキシン / 睡眠障害 / Noradrenaline / グラフイックスソフトウエア / Cre / 発熱 / X-ray crystallography / βトレース / PGD還元活性 / interstitial cell / A_1 receptor / Cloning / Histamine H_1 receptor / クローニング / PGF2alpha / ventral striatum / PGF synthase / ニューロン / アミノ酸配列 / 側座核 / Purification of Enzyme / A2A Receptor / 無機セレン化合物 / アデノ随伴ウィルス / カルシウム結合蛋白質 / ノルアドレナリン / HMG-CoA還元酵素阻害剤 / アラキドン酸カスケード / CGS21680 / アレルギー / A_<2A>体受容体 / DARPP-32 phosphorylation / beta-trace / Transporter / 発光蛋白質 / 肺 / PGE合成酵素 / Continuous infusion / Gene-manipulated mice / 視束前野 / 膜結合型酵素 / 遺伝子欠損マウス / 部位特異的変異 / クロニジン / 等電点電気泳動 / Preoptic area / Neuron / 神経破壊 / Microdialysis / トリパノソーマ / アイソザイム / プロスタグランディン / uterus / Prostaglandins / Al receptor / Prostaglandin synthase Less

Developing focal RNA interference for the identification of neural entry points for sleep-promoting adenosine
- Principal Investigator
  
  LAZARUS Michael
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  公益財団法人大阪バイオサイエンス研究所
   Osaka Bioscience Institute
Exploration of biological marker of insomnia
- Principal Investigator
  
  ARITAKE Kosuke
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Osaka Bioscience Institute
Role of adenosine A_2A receptor in olfactory nuclei in sleep-wake regulation
- Principal Investigator
  
  WEI Min Qu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Osaka Bioscience Institute
Crosstalk of signal transduction in sleep-wake regulationPrincipal Investigator
- Principal Investigator
  
  HAYASHI Osamu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka Bioscience Institute
Roles of adenosine A2A receptors in sleep-wake regulation
- Principal Investigator
  
  HUANG Zhi Li
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  睡眠学
- Research Institution
  Osaka Bioscience Institute
Molecular mechanism of wakefulness regulationPrincipal Investigator
- Principal Investigator
  
  HAYAISHI Osamu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka Bioscience Institute
Sleep research by gene-manipulated adenosine receptor knockout mice
- Principal Investigator
  
  HUANG Zhi-Li
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  睡眠学
- Research Institution
  Osaka Bioscience Institute
Studies on cytokine-induced sleep in prostanoid-related gene-manipulated micePrincipal Investigator
- Principal Investigator
  
  HAYAISHI Osamu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka Bioscience Institute
Trypanosama bruceiにおけるプロスタグランジン生合成経路Principal Investigator
- Principal Investigator
  
  早石修
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Osaka Bioscience Institute
Designing of inhibitors for prostaglandin D synthases based on crystallographic analyses
- Principal Investigator
  
  URADE Yoshihiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  OSAKA BIOSCIENCE INSTITUTE
Thypanosama bruceiにおけるプロスタグランジン生合成経路
- Principal Investigator
  
  裏出良博
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Osaka Bioscience Institute
Novel function of prostaglandin D2 and its metabolites in pathogenesis of immune and allergic diseases as examined by prostaglandin D synthase gene-manipulated mice
- Principal Investigator
  
  URADE Yoshihiro, PINZAR Elena I.
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka Bioscience Institute
Plasmodium falciparumにおけるプロスタグランジンの機能
- Principal Investigator
  
  URADE Yoshihiro
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka Bioscience Institute
A new type of the gene-sharing on prostaglandin D synthases
- Principal Investigator
  
  URADE Yoshihiro
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka Bioscience Institute
Enzymatic Properties and Physiological Role of Membrane bound-Prostaglandin E Synthase
- Principal Investigator
  
  WATANABE Kikuko
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  University of East Asia
  Osaka Bioscience Institute
Functional analysis of secretory prostaglandin D synthase by gene-targeting
- Principal Investigator
  
  URADE Yoshihiro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka Bioscience Institute
Molecular biological analysis of animal behavior : Generation of genetically insomniac animals
- Principal Investigator
  
  URADE Yoshihiro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  Osaka Bioscience Institute
Roles of prostaglandins D_2 and E_2 in the site of action for their sleep-wake regulation
- Principal Investigator
  
  MATSUMURA Hitoshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Osaka Bioscience Institute
Molecular biological study of sleep-wake regulating mechanisms and its clinical implicationPrincipal Investigator
- Principal Investigator
  
  HAYAISHI Osamu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka Bioscience Institute
Implication of prostaglandins in models of sleep-wake (conscious) disorders prepared in experimental animals (looking for a clue to a novel drug to treat sleep-wake disorders)
- Principal Investigator
  
  MATSUMURA Hitoshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Bioscience Institute
The structure and function of prostaglandin F synthase. (a dual function enzyme)
- Principal Investigator
  
  WATANABE Kikuko
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Bioscience Institute
Effects of prostaglandin and noradrenalin on sleep-related neurons in the preoptic area.
- Principal Investigator
  
  OSAKA Toshimasa
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  OSAKA BIOSCIENCE INSTITUTE
Neural circuit for the sleep-wake regulation by prostaglandins D_2 and E_2Principal Investigator
- Principal Investigator
  
  HAYAISHI Osamu
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka Bioscience Institute
オキシゲナ-ゼの生理機能に関する分子遺伝学的研究Principal Investigator
- Principal Investigator
  
  早石修
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka Bioscience Institute
Artificial regulation of the sleep-wake state of an experimental animal (rat).
- Principal Investigator
  
  MATUSMURA Hitoshi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka Bioscience Institute
睡眠をはじめとする意識レベルの変化に伴う脳代謝動態の解析と精神科領域への応用Principal Investigator
- Principal Investigator
  
  早石修
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Bioscience Institute
Molecular mechanisms of sleep-wake regulation and their relationships to the physiological state of the bodyPrincipal Investigator
- Principal Investigator
  
  HAYAISHI Osamu
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka Bioscience Institute
The structure and function of PGF synthase
- Principal Investigator
  
  WATANABE Kikuko
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka Bioscience Instutute
Genetic Engineering Modification of Aequorin for Detection of Metal Ions
- Principal Investigator
  
  TSUJI Frederick I.
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  物質生物化学
- Research Institution
  Osaka Bioscience Institute

All 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens2011
- Author(s)
  Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass C, Winsky-Sommerer R, Semba K, Fredholm B, Boison D, Hayaishi O, Urade Y, Chen JF.
- Journal Title
  
  J Neurosci
  
  Volume: 31巻 Pages: 10067-10075
- DOI
  10.1523/jneurosci.6730-10.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300133, KAKENHI-PROJECT-21380081, KAKENHI-PROJECT-21500313
[Journal Article] Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase2009
- Author(s)
  Kumasaka T, Aritake K, Ago H, Irikura D, Tsurumura T, Yamamoto M, Miyano M, Urade Y, Hayaishi O
- Journal Title
  
  J Biol Chem. 284(33)
  
  Pages: 22344-52
- Data Source
  KAKENHI-PROJECT-20406006
[Journal Article] Prostaglandins and the regulation of sleep and wakefulness2008
- Author(s)
  Hayaishi, O., Urade, Y.
- Journal Title
  
  Neurochemistry of Sleep and Wakefulness. Ed. Monti, J. M., Pandi-Perumal, S. R., and Sinton, C. M., Cambridge University Press
  
  Pages: 363-386
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Prostaglandins and the regulation of sleep and wakefulness.2008
- Author(s)
  Hayaishi,O.and Urade, Y.
- Journal Title
  
  Neurochemistry of Sleep and Wakefulness. Ed. Monti, J. M., Pandi-Perumal, S. R., and Sinton, C. M., Cambridge University Press
  
  Pages: 363-386
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007
- Author(s)
  Huang Z L, Urade Y, Hayaishi O.
- Journal Title
  
  Curr. Opin. Pharmacol. 7
  
  Pages: 33-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007
- Author(s)
  Huang ZL, Urade Y, Hayaishi O.
- Journal Title
  
  Curr. Opin. Pharmacol. 7
  
  Pages: 33-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18603011
[Journal Article] Odyssey of a Biochermist.2007
- Author(s)
  Hayaishi,O.
- Journal Title
  
  Comprehensive Biochemistry Vol.45: Stories of Success-Personal Recollections. X. Ed. Semenza, G.,Elsevier B.V.
  
  Pages: 1-36
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007
- Author(s)
  Huang ZL,Urade Y and Hayaishi O.
- Journal Title
  
  Curr. Opin. Pharmacol. 7
  
  Pages: 33-38
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] 眠りの秘密2007
- Author(s)
  早石修
- Journal Title
  
  睡眠医療 Vol.2
  
  Pages: 7-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007
- Author(s)
  Huang ZL, Urade Y and Hayaishi O.
- Journal Title
  
  Curr.Opin.Pharmacol. 7
  
  Pages: 33-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007
- Author(s)
  Huang ZL,Urade Y and Hayaishi O.
- Journal Title
  
  Curr Opin Pharmacol 7(1)
  
  Pages: 33-38
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18603011
[Journal Article] Odyssey of a Biochermist2007
- Author(s)
  Hayaishi, O.
- Journal Title
  
  Comprehensive Biochemistry Vol.45:Stories of Success-Personal Recollections. X. Ed. Semenza, Cz, Elsevier B.V.
  
  Pages: 1-36
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007
- Author(s)
  Huang ZL, Uade Y, Hayaishi O.
- Journal Title
  
  Curr Opin Pharmacol 7
  
  Pages: 33-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18603011
[Journal Article] Odyssey of a Biochermist.2007
- Author(s)
  Hayaishi, O.
- Journal Title
  
  Comprehensive Biochemistry : Stories of Success-Personal Recollections. X. Ed. Semenza, G., Elsevier B. V. Vol.45
  
  Pages: 1-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007
- Author(s)
  Huang ZL, Urada Y, Hayaishi O.
- Journal Title
  
  Curr Opin Pharmacol 7(1)
  
  Pages: 33-38
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Prostaglandins and adenosine in the regulation of sleep and wakefulness2007
- Author(s)
  Huang ZL, Urade Y, Hayaishi O.
- Journal Title
  
  Curr Opin Pharmacol 7(1)
  
  Pages: 33-38
- Data Source
  KAKENHI-PROJECT-18603011
[Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D_2 involved in regulation of physiological sleep2006
- Author(s)
  Qu WM,Huang ZL,Xu XH,Aritake K,Eguchi N,Nambu F,Narumiya S,Urade Y and Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(47)
  
  Pages: 17949-17954
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Alterations of sleep-wake behavioral characterisitcs and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006
- Author(s)
  Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(12)
  
  Pages: 4687-4692
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006
- Author(s)
  Huang ZL, Mochizuki T, Qu WM.Hong ZY, Watanabe T, Urade Y, Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(12)
  
  Pages: 4687-4692
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice2006
- Author(s)
  Huang Z L, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(12)
  
  Pages: 4687-4692
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Lipocalin-type prostaglandin D synthase as an enzymic lipocalin.2006
- Author(s)
  Urade, Y., Eguchi, N., Hayaishi, O.
- Journal Title
  
  Lipocalins. (In press)
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006
- Author(s)
  Huang ZL,Mochizuki T,Qu WM,Hong ZY,Watanabe T,Urade Y and Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(12)
  
  Pages: 4687-4692
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18603011
[Journal Article] Altered sleep-wake characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice.2006
- Author(s)
  Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O
- Journal Title
  
  Proc Natl Acad Sci USA 103(12)
  
  Pages: 4687-4692
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D_2 involved in regulation of physiological sleep.2006
- Author(s)
  Qu WM, Huang ZL, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y, Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(47)
  
  Pages: 17949-17954
- Data Source
  KAKENHI-PROJECT-18603011
[Journal Article] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006
- Author(s)
  Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(12)
  
  Pages: 4687-4692
- Data Source
  KAKENHI-PROJECT-18603011
[Journal Article] Lipocalin-type prostaglandin D synthase as an enzyme lipocalin2006
- Author(s)
  Urade Y, Eguchi N, Hayaishi O.
- Journal Title
  
  Lipocalins, edited by Bo Akerstrom, et al. Eurekah. com, Georgetown, TX Chapter 9
  
  Pages: 99-109
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep2006
- Author(s)
  Qu WM, Huang Z L, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y, Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(47)
  
  Pages: 17949-17954
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D_2 involved in regulation of physiological sleep2006
- Author(s)
  Qu WM,Huang ZL,Xu XH,Aritake K,Eguchi O,Nambu F,Narumiya S,Urade Y and Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(47)
  
  Pages: 17949-17954
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18603011
[Journal Article] Lipocalin-type prostaglandin D synthase produces prostaglandin D_2 involved in regulation of physiological sleep2006
- Author(s)
  Qu WM, Huang ZL, Xu XH, Aritake K, Eguchi N, Nambu F, Narumiya S, Urade Y, Hayashi O.
- Journal Title
  
  Proc Natl Acdd Sci USA 103(47)
  
  Pages: 17949-17954
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Memoirs of a biochemist2006
- Author(s)
  Hayaishi O.
- Journal Title
  
  IUBMB Life 58(5-6)
  
  Pages: 242-245
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine h1 receptor knockout mice2006
- Author(s)
  Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y, Hayaishi O.
- Journal Title
  
  Proc Natl Aci USA 103(12)
  
  Pages: 4687-4692
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18603011
[Journal Article] Lipocalin-type prostaglandin D synthase as an enzymic lipocalin.2006
- Author(s)
  Urade, Y., Eguchi, N., Hayaishi, O.
- Journal Title
  
  Lipocalins (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Lipocalin-type prostaglandin D synthase as an enzyme lipocalin2006
- Author(s)
  Urade Y, Eguchi N, Hayaishi O.
- Journal Title
  
  Lipocalins, edited by Bo Akerstrom, et. al. Eurekah. com, Georgetown, TX, Chapter 9
  
  Pages: 99-109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Altered sleep-wake characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006
- Author(s)
  Huang, Z.-L., Mochizuki, T., Qu, W.-M., Hong, Z.-Y., Watanabe, T., Urade, Y., Hayaishi, O.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103
  
  Pages: 4687-4692
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Altered sleep-wake characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice.2006
- Author(s)
  Huang, Z.-L., Mochizuki, T., Qu, W.-M., Hong, Z.-Y., Watanabe, T., Urade, Y., Hayaishi, O.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103(12)
  
  Pages: 4687-4692
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice2006
- Author(s)
  Huang ZL,Mochizuki T,Qu WM,Hong ZY,Watanabe T,Urade Y and Hayaishi O.
- Journal Title
  
  Proc Natl Acad Sci USA 103(12)
  
  Pages: 4687-4692
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Lipocalin-type prostaglandin D synthase as an enzyme lipocalin2006
- Author(s)
  Urade Y,Eguchi N and Hayaishi O.
- Journal Title
  
  Lipocalins, edited by Bo Akerstrom, et al. Eurekah.com,Georgetown,TX Chapter9
  
  Pages: 99-109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Journal Article] Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine.2005
- Author(s)
  Huang ZL, Qu WM, Eguchi, N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O
- Journal Title
  
  Nat Neurosci 8(7)
  
  Pages: 858-859
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Preface.2005
- Author(s)
  Hayaishi, O, et al.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 338
  
  Pages: 1-1
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Fifty Years of Oxygen Activation.2005
- Author(s)
  Hayaishi, O.
- Journal Title
  
  J. Biol. Inorg. Chem. 10
  
  Pages: 1-2
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Adenosine A_<2A>, but not A_1, receptors mediate the arousal effect of caffeine2005
- Author(s)
  Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O.
- Journal Title
  
  Nat Neurosci 8(7)
  
  Pages: 858-859
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic in rats.2005
- Author(s)
  Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayaishi O.
- Journal Title
  
  J Neurochem 92
  
  Pages: 1542-1549
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.2005
- Author(s)
  Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayaishi O.
- Journal Title
  
  J Neurochem 92
  
  Pages: 1542-1549
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Fifty Years of Oxygen Activation.2005
- Author(s)
  Hayaishi, O.
- Journal Title
  
  J.Biol.Inorg.Chem. 10
  
  Pages: 1-2
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] An odyseey with oxygen.2005
- Author(s)
  Hayaishi, O.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 338
  
  Pages: 2-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] An odyssey with oxygen.2005
- Author(s)
  Hayaishi, O.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 338
  
  Pages: 2-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Molecular mechanisms of sleep-wake regulation : a role of prostaglandin D_2 and adenosine.2005
- Author(s)
  Hayaishi, O.
- Journal Title
  
  Sleep : Circuits and Functions.
  
  Pages: 65-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Preface.2005
- Author(s)
  Hayaishi, O., Coon, M.J., Estabrook, R.W., Que, L., Yamamoto, S.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 338
  
  Pages: 1-1
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminereic systems in rats.2005
- Author(s)
  Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayaishi O
- Journal Title
  
  J Neurochem 92
  
  Pages: 1542-1549
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] The endogenous somnogen adenosine excites a subset of sleep-promoting neurons via A_<2A> receptors in the ventrolateral preoptic nucleus.2005
- Author(s)
  Gallopin, T., Luppi, P.-H., Cauli, B., Urade, Y., Rossier, J., Hayaishi, O., Lambolez, B., Fort, P
- Journal Title
  
  Neuroscience 134
  
  Pages: 1377-1390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] IUB(MB) 50^<th> Anniversary.2005
- Author(s)
  Hayaishi, O
- Journal Title
  
  IUBMB Life 57
  
  Pages: 213-214
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] IUB (MB) 50^<th> Anniversary.2005
- Author(s)
  Hayaishi, O.
- Journal Title
  
  IUBMB Life 57(4/5)
  
  Pages: 213-214
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] IUB(MB) 50^<th> Anniversary.2005
- Author(s)
  Hayaishi, O.
- Journal Title
  
  IUBMB Life 57(4/5)
  
  Pages: 213-214
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Adenosine A_<2A>, but not A_1, receptors mediate the arousal effect of caffeine.2005
- Author(s)
  Huang, Z.-L., Qu, W.-M., Eguchi, N., Chen, J.-F., Schwarzschild, M.A., Fredholm, B.B., Urade, Y., Hayaishi, O.
- Journal Title
  
  Nat.Neurosci. 8
  
  Pages: 858-859
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Fifty Years of Oxygen Activation.2005
- Author(s)
  Hayaishi, O
- Journal Title
  
  J.Biol.Inorg.Chem. 10
  
  Pages: 1-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Adenosine A_<2A>, but not A_1, receptors mediate the arousal effect of caffeine2005
- Author(s)
  Huang, Z.-L., Qu, W-M., Eguchi, N., Chen, J.-F., Schwarzschild, M.A., Fredholm, B.B., Urade, Y., Hayaishi, O
- Journal Title
  
  Nat.Neurosci. 8
  
  Pages: 858-859
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.2005
- Author(s)
  Hong, Z.-Y., Huang, Z.-L., Qu, W.-M., Eguchi, N., Urade, Y., Hayaishi, O.
- Journal Title
  
  J.Neurochem. 92
  
  Pages: 1542-1549
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Preface.2005
- Author(s)
  Hayaishi, O., Coon, M.J., Estabrook, R.W., Que, L., Yamamoto, S
- Journal Title
  
  Biochem.Biophys.Res.Commun. 338
  
  Pages: 1-1
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.2005
- Author(s)
  Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayaishi O
- Journal Title
  
  J Neurochem 92
  
  Pages: 1542-1549
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] An adenosine A_<2A> receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.2005
- Author(s)
  Hong ZY, Huang ZL, Qu WM, Eguchi N, Urade Y, Hayashi O.
- Journal Title
  
  J Neurochem 92
  
  Pages: 1542-1549
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] The endogenous somnogen adenosine excites a subset of sleep-promoting neurons via A_<2A> receptors in the ventrolateral preoptic nucleus.2005
- Author(s)
  Gallopin, T., Luppi, P.-H., Cauli, B., Urade, Y., Rossier, J., Hayaishi, O., Lambolez, B., Fort, P.
- Journal Title
  
  Neuroscience 134
  
  Pages: 1377-1390
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Functional analyses of lipocalin-type and hematopoietic prostaglandin D synthases.2004
- Author(s)
  Urade Y, Eguchi N, Aritake K, Hayaishi O
- Journal Title
  
  Folia Pharmacol.Jpn. 123
  
  Pages: 5-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission.2004
- Author(s)
  Hayaishi O, Huang ZL
- Journal Title
  
  Drug News Perspect 17(2)
  
  Pages: 105-109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission.2004
- Author(s)
  Hayashi O, Huang ZL
- Journal Title
  
  Drug News Perspect 17(2)
  
  Pages: 105-109
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep.2004
- Author(s)
  Hayaishi O, Urade Y, Eguchi N, Huang ZL
- Journal Title
  
  Arch Ital Biol 142
  
  Pages: 533-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] リポカリン型および造血器型プロスタグランジンD合成酵素の機能解析2004
- Author(s)
  裏出良博, 江口直美, 有竹浩介, 早石修
- Journal Title
  
  日薬理誌(Folia Pharmacol. Jpn.) 123
  
  Pages: 5-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission.2004
- Author(s)
  Hayaishi O, Huang ZL
- Journal Title
  
  Drug News Perspect 17
  
  Pages: 105-109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep.2004
- Author(s)
  Hayashi O, Urade Y, Eguchi N, Huang ZL
- Journal Title
  
  Arch Ital Biol 142
  
  Pages: 533-553
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission2004
- Author(s)
  Hayaishi, O, Huang ZL.
- Journal Title
  
  Drug News Perspect 17(2)
  
  Pages: 105-109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Histaminergic role in sleep-wake cycle of orexin, adenosine, and prostaglandin E_2 and D_2.2004
- Author(s)
  Huang ZL, Qu WM, Eguchi N, Chu M, Okada T, Sato, Y, Sakata M, Mochizuki T, Urade Y, Hayaishi O
- Journal Title
  
  Sleep Biol Rhythm 2
  
  Pages: 21-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep.2004
- Author(s)
  Hayaishi O, Urade Y, Eguchi N, Huang ZL
- Journal Title
  
  Arch Ital Biol 142
  
  Pages: 533-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Histaminergic role in sleep-wake cycle of orexin, adenosine, and prostaglandin E2 and D2.2004
- Author(s)
  Huang ZL, Qu WM, Eguchi N, Chu M, Okada T, Sato, Y, Sakata M, Mochizuki T, Urade Y, Hayaishi O
- Journal Title
  
  Sleep Biol Rhythm 2
  
  Pages: 21-22
- Data Source
  KAKENHI-PROJECT-16614014
[Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep.2004
- Author(s)
  Hayashi O, Urabe Y, Eguchi N, Huang ZL
- Journal Title
  
  Arch Ital Biol 142
  
  Pages: 533-553
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotrallsmission.2004
- Author(s)
  Hayaishi O, Huang ZL
- Journal Title
  
  Drug News Perspect 17(2)
  
  Pages: 105-109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Role of orexin and prostaglandin E_2 in activating histaminergic neurotransmission.2004
- Author(s)
  Hayaishi O, Huang ZL
- Journal Title
  
  Drug News Perspect 17(2)
  
  Pages: 105-109
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep.2004
- Author(s)
  Hayaishi O, et al.
- Journal Title
  
  Arch Ital Biol 142
  
  Pages: 533-539
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300123
[Journal Article] Genes for prostaglandin D synthase and receptor as well as adenosine A_<2A> receptor are involved in the homeostatic regulation of NREM sleep2004
- Author(s)
  Hayaishi O, et al.
- Journal Title
  
  Arch Ital Biol 142
  
  Pages: 535-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16614014
[Presentation] The role of adenosine A2A receptors in the nucleus accumbens for sleep-wake regulation2011
- Author(s)
  Lazarus M, Urade Y, Hayaishi O
- Organizer
  WORLDSLEEP2011-6th Quadrennial Congress of the World Sleep Federation
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of adenosine A_<2A> receptors in the nucleus accumbens for sleep-wake regulation2011
- Author(s)
  Lazarus M, Urade Y, Hayaishi O.
- Organizer
  WORLDSLEEP2011-6th Quadrennial Congress of the World Sleep Federation
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of the nucleus accumbens in the regulation of behavioral arousal2011
- Author(s)
  Lazarus M, Urade Y, Hayaishi O.
- Organizer
  21st World Congress on Psychosomatic Medicine
- Place of Presentation
  ソウル、韓国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] Immunohistochemical localization of the vesicular ATP transporter(VNUT) in the rat central nervous system and its role in sleep-wake regulation2010
- Author(s)
  Lazarus M, Hiasa M, Ko Mitamura E, Cherasse Y, Moriyama Y, Urade Y, Hayaishi O.
- Organizer
  Neuroscience 2010【40th Annual Meeting of the Society for Neuroscience】
- Place of Presentation
  サンディエゴ、米国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of extracellular adenosine in the basal ganglia for sleep-wake regulation2010
- Author(s)
  Lazarus M, Urade Y, Hayaishi O.
- Organizer
  Neuro2010【第33回日本神経科学大会】
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of the nucleus accumbens shell in the regulation of behavioral arousal2010
- Author(s)
  Lazarus M, Urade Y, Hayaishi O
- Organizer
  6th Congress of the Chinese Sleep Research Society
- Place of Presentation
  成都、中国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of prostaglandin D_2 in causing post-ictal sleep following seizures2010
- Author(s)
  Lazarus M, Kaushik MK, Moriyama T, Qu WM, Aritake K, Rahman MA, Huang ZL, Urade Y, Hayaishi O.
- Organizer
  Neuroscience 2010【41th Annual Meeting of the Society for Neuroscience】
- Place of Presentation
  ワシントン、米国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] The role of extracellular adenosine in the basal ganglia for sleep-wake regulation2010
- Author(s)
  Lazarus M, Urade Y, Hayaishi O.
- Organizer
  6th Congress of the Chinese Sleep Research Society
- Place of Presentation
  成都、中国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] Immunohistochemical localization of the vesicular ATP transporter(VNUT)in the rat central nervous system and its role in sleep wake regulation2010
- Author(s)
  Lazarus M, Hiasa M, Ko Mitamura E, Cherasse Y, Moriyama Y, Urade Y, Hayaishi O
- Organizer
  Neuroscience 2010【40th Annual Meeting of the Society for Neuroscience】
- Place of Presentation
  サンディエゴ、米国
- Data Source
  KAKENHI-PROJECT-21300133
[Presentation] Interluekine-1. Induces sleep independent of prostaglandin D22008
- Author(s)
  Wei-Min Qu, Zhi-Li Huang, Yoshihiro Urade and Osamu Hayaishi
- Organizer
  日本睡眠学会第33回定期学術集会
- Place of Presentation
  福島県郡山市
- Data Source
  KAKENHI-PROJECT-19500283
[Presentation] Dopaminergic D_1 and D_2 receptors are essential for the arousal effect of modafinil2008
- Author(s)
  Wei-Min Qu, Zhi-Li Huang, Naomi Matsumoto, Xin-Hong Xu, Yoshihiro Urade, Osamu Hayaishi
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19500283
[Presentation] Interluekine-1β induces sleep independent of prostaglandin D_22008
- Author(s)
  Wei-Min Qu, Zhi-Li Huang, Yoshihiro Urade, Osamu Hayaishi
- Organizer
  日本睡眠学会第33回定期学術集会
- Place of Presentation
  福島県郡山市
- Data Source
  KAKENHI-PROJECT-19500283
[Presentation] Adenosine A_2A Receptor Deficiency Attenuates the Somnogenic Effect of Prostaglandin D_22007
- Author(s)
  Wei-Min Qu, Zhi-Li Huang, Yoshihiro Urade, Osamu Hayaishi
- Organizer
  Worldsleep07, 5th world sleep congress of WFSRSMS
- Place of Presentation
  Cairns, Australia
- Data Source
  KAKENHI-PROJECT-19500283
[Presentation] Prostaglandin D_2 plays a crucial role in circadian and homeostatic regulation of physiological sleep2007
- Author(s)
  Osamu Hayaishi
- Organizer
  Worldsleep07 (The 5th World Congress of the World Federation of Sleep Research and Sleep Medicine Societies)
- Place of Presentation
  Cairns Convention Centre,Cairns,Australia
- Year and Date
  2007-09-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] 眠りの謎2007
- Author(s)
  早石修
- Organizer
  日本学士院第2部談話会
- Place of Presentation
  日本学士院(東京)
- Year and Date
  2007-03-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Sleep propensity is necessary for the sleep induction of histamine H1 receptor antagonist2007
- Author(s)
  Huang, Z-L., Qu, W-M., Matsumoto, N., Wada, M., Urade, Y., Hayaishi, O.
- Organizer
  The 32ad Annual Meeting of Japanes Sleep Research Society
- Place of Presentation
  Tokyo, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18603011
[Presentation] Adenosine A2A Receptor Mainly Mediates the Somnogenic Effect of Prostaglandin D22007
- Author(s)
  Wei-Min Qu, Zhi-Li Huang, Yoshihiro Urade, Osamu Hayaishi
- Organizer
  日本睡眠学会第32回定期学術集会・第14回日本時間生物学会学術大会合同大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19500283
[Presentation] 眠りの秘密2007
- Author(s)
  早石修
- Organizer
  大阪医科大学創立80周年記念特別市民講演会
- Place of Presentation
  高槻市立文化ホール「現代劇場」(大阪)
- Year and Date
  2007-12-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] 眠りを科学する2007
- Author(s)
  早石修
- Organizer
  (財)大阪バイオサイエンス研究所創立20周年記念講演会
- Place of Presentation
  大阪市中央公会堂中集会室(大阪)
- Year and Date
  2007-10-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Prostaglandin D2 plays a crucial role in circadian and homeostatic regulation of physiological sleep2007
- Author(s)
  Osamu Hayaishi
- Organizer
  Worldsleep07(The 5th World Congress of the World Federation of Sleep Research and Sleep Medicine Societies)
- Place of Presentation
  Cairns Convention Centre, Cairns, Australia
- Year and Date
  2007-09-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Sleep propensity is necessary for the sleep induction of histamine H_1 receptor antagonist2007
- Author(s)
  Huang,ZL.,Qu,WM.,Matsumoto,N.,Wada,M.,Urade,Y.& Hayaishi, O.
- Organizer
  The 32nd Annual Meeting of Japanese Sleep Research Society
- Place of Presentation
  Tokyo,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18603011
[Presentation] Adenosine A_<2A> Receptor Deficiency Attenuates the Somnogenic Effect of Prostaglandin D_22007
- Author(s)
  Wei-Min Ou, Zhi-Li Huang, Yoshihiro Urade, Osamu Hayaishi
- Organizer
  WorldsleepO7, 5th world sleep congress of WFSRSMS
- Place of Presentation
  Cairns,Australia
- Data Source
  KAKENHI-PROJECT-19500283
[Presentation] 睡眠の謎に迫る-わが睡眠医学研究-2006
- Author(s)
  早石修
- Organizer
  大阪大学睡眠学談話会第1回講演会
- Place of Presentation
  大阪大学医学部銀杏会館(大阪)
- Year and Date
  2006-07-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice2006
- Author(s)
  Huang, Z.L., Mochizuki, T., Qu, W. M., Hong, Z. Y., Watanabe, T., Urade, Y., Hayaishi, O.
- Organizer
  The 20th International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18603011
[Presentation] Alterations of sleep-wake behavioral characteristics and lack of arousal response to H_3 receptor antagonist in histamine H_1 receptor knockout mice2006
- Author(s)
  Huang,Z.L.,Mochizuki,T.,Qu,W.M.,Hong,Z.Y.,Watanabe,T.,Urade,Y.&Hayaishi,O.
- Organizer
  The 20th International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Kyoto,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18603011
[Presentation] 眠りの秘密2006
- Author(s)
  早石修
- Organizer
  日本睡眠学会第31回定期学術集会教育講演
- Place of Presentation
  大津プリンスホテル(滋賀)
- Year and Date
  2006-06-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Role of prostaglandin D2 in the homeostatic and circadian regulation of sleep2006
- Author(s)
  Osamu Hayaishi
- Organizer
  Invited Lecture
- Place of Presentation
  University of Pennsylvania, School of Medicine, Philadelphia, USA
- Year and Date
  2006-07-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Role of prostaglandin D_2 in the homeostatic and circadian regulation of sleep2006
- Author(s)
  Osamu Hayaishi
- Organizer
  Invited Lecture, Thomas Jefferson Medical Collage
- Place of Presentation
  Thomas Jefferson Medical Collage,Philadelphia,USA
- Year and Date
  2006-07-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Is prostaglandin D_2 essential for physiological sleep?2006
- Author(s)
  Osamu Hayaishi
- Organizer
  Symposium "Sleep and Clock: Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto Takaragaike Prince Hotel,Kyoto,Japan
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Is prostaglandin D2 essential for physiological sleep?2006
- Author(s)
  Osamu Hayaishi
- Organizer
  Symposium Sleep and Clock : Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto Takaragaike Prince Hotel, Kyoto, Japan
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] The birth of oxygenases2006
- Author(s)
  Osamu Hayaishi
- Organizer
  The 14th Takeda Science Foundation Symposium on Bioscience The 50th anniversary of oxygenases -advances and reflections-
- Place of Presentation
  Kyoto Hotel Okura, Kyoto, Japan
- Year and Date
  2006-04-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] The birth of oxygenases2006
- Author(s)
  Osamu Hayaishi
- Organizer
  The 14th Takeda Science Foundation Symposium on Bioscience "The 50th anniversary of oxygenases-advances and reflections-"
- Place of Presentation
  Kyoto Hotel Okura,Kyoto,Japan
- Year and Date
  2006-04-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Role of prostaglandin D_2 in the homeostatic and circadian regulation of sleep2006
- Author(s)
  Osamu Hayaishi
- Organizer
  Invited Lecture, Stanford University School of Medicine, Sleep Research Center
- Place of Presentation
  Stanford University School of Medicine, Sleep Research Center,Palo Alto,USA
- Year and Date
  2006-07-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Role of prostaglandin D_2 in the homeostatic and circadian regulation of sleep2006
- Author(s)
  Osamu Hayaishi
- Organizer
  Invited Lecture, University of Pennsylvania, School of Medicine
- Place of Presentation
  University of Pennsylvania,School of Medicine, Philadelphia,USA
- Year and Date
  2006-07-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] Role of prostaglandin D_2 in the homeostatic and circadian regulation of sleep2006
- Author(s)
  Osamu Hayaishi
- Organizer
  Invited Lecture, The National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) at NIH
- Place of Presentation
  The National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) at NIH,Bethesda,USA
- Year and Date
  2006-07-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] The birth of oxygenases2006
- Author(s)
  Osamu Hayaishi
- Organizer
  Commemorative Symposium Structures and functions of oxygenases : In commemoration of the 50th anniversary of the discovery of oxygenases 20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto International Conference Hall, Kyoto, Japan
- Year and Date
  2006-06-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300129
[Presentation] The birth of oxygenases2006
- Author(s)
  Osamu Hayaishi
- Organizer
  Commemorative Symposium "Structures and functions of oxygenases: In commemoration of the 50th anniversary of the discovery of oxygenases" 20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto International Conference Hall,Kyoto,Japan
- Year and Date
  2006-06-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300129

1. URADE Yoshihiro (10201360)

# of Collaborated Projects: 18 results

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HAYAISHI Osamu 早石 修

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Crosstalk of signal transduction in sleep-wake regulationPrincipal Investigator

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Molecular mechanism of wakefulness regulationPrincipal Investigator

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Studies on cytokine-induced sleep in prostanoid-related gene-manipulated micePrincipal Investigator

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Trypanosama bruceiにおけるプロスタグランジン生合成経路Principal Investigator

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HAYAISHI Osamu 早石修