KOJIMA Yoshitane 小嶋良種

Researcher Number	40047139
External Links
Affiliation (based on the past Project Information) *help	2004: 大阪市立大学, 大学院・理学研究科, 特任教授 1997 – 1999: 大阪市立大学, 理学部, 教授 1996: 大阪市立大学, 理学部, 助教授
Review Section/Research Field	Principal Investigator Inorganic chemistry Except Principal Investigator Chemistry / Science and Engineering
Keywords	Principal Investigator Aspartic Acid Derivatives / DTA / TG / CD Spectra / Histidine Derivatives / Insulin-like Activities / X-Ray Analyses / Oxovanadium Complexes / N, N'-Ethylene-bis (amino acids) / 熱分析 … More / N,N'-エチレンビス-D-アミノ酸 / アスパラギン酸誘導体 / 熱天秤・示差熱分析 / CDスペクトル / ヒスチジン誘導体 / インスリン様作用 / X線解析 / オキソバナジウム錯体 / N,N'-エチレンビスアミノ酸 / エチレン架橋ジペプチド / 銅錯体 / チロシン / ヒスチジン / 金属酵素モデル / 銅(II)錯体 / N,N'-エチレン架橋ジペプチド … More Except Principal Investigator drug delivery system / hypoglycemic effect / insulin-mimetic action / zinc complex / vanadium complex / metabolic syndrome / diabetes mellitus / インスリンシグナル伝達経路 / アリキシン / 亜鉛 / バナジウム / 金属錯体 / インスリン注射 / 糖尿病治療薬 / ポルフィリン錯体 / ドラッグデリバリー系 / 糖尿病治療 / ドラッグデリバリーシステム / 血糖降下作用 / インスリン様作用 / 亜鉛錯体 / バナジウム錯体 / メタボリックシンドローム / 糖尿病 Less

Development of Metal Complexes with Antidialetic Effect
- Principal Investigator
  
  SAKURAI Hiromu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Kyoto Pharmaceutical University
Syntheses of Vanadium Complexes with Bis-amino Acid Derivatives and Evaluations of their Insulin-like ActivitiesPrincipal Investigator
- Principal Investigator
  
  KOJIMA Yoshitane
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Inorganic chemistry
- Research Institution
  Osaka City University
アミノ酸の側鎖官能基のみが銅(II)イオンに配位したガラクトースオキシダーゼモデルPrincipal Investigator
- Principal Investigator
  
  小嶋良種
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Inorganic chemistry
- Research Institution
  Osaka City University

All 2006 2005 2004

All Journal Article

[Journal Article] Inhibition mode and inhibitory effect in vivo to aipha-glucosidase of Zn(II) complex with picolinamide derivatives2006
- Author(s)
  Eriko Ueda, Yutaka Yoshikawa, Hiromu Sakurai, Yoshitane Kojima, Kinuyo Matsumoto, Naemi M. Kajiwara
- Journal Title
  
  Nippon Byotai Eiyogaku Kaishi 9(1)
  
  Pages: 59-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Zinc(II) complexes with allixin-derivatives as oral therapeutics for type 2 diabetes2006
- Author(s)
  Yusuke Adachi, Yutaka Yoshikawa, Jiro Yoshida, Yukihiro Kodera, Akira Katoh, Yoshitane Kojima, Hiromu Sakurai
- Journal Title
  
  Biomed. Res. Trace Elements 17(1)
  
  Pages: 17-24
- NAID
  10018127407
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Synthesis, structure, and in vitro and in vivo insulinomimetic activities of the zinc(II)-6-ethylpicolinate complex.2005
- Author(s)
  Yoshitane Kojima
- Journal Title
  
  Bull.Chem.Soc.Jpn. 78・3
  
  Pages: 451-455
- NAID
  10015431988
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Synthesis, structure, and in vitro and in vivo insulinomimetic activities of the zinc(II)-6-ethylpicolinate complex2005
- Author(s)
  Yoshitane Kojima, Yutaka Yoshikawa, Eriko Ueda, Noriko Kishimoto, Makoto Tadokoro, Hiromu Sakurai
- Journal Title
  
  Bull. Chem. Soc. Jpn. 78(3)
  
  Pages: 451-455
- NAID
  10015431988
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Antidiabetic activity of Zn(II) complexes with a derivative of L-glutamine2005
- Author(s)
  Kinuyo Matsumoto, Shuhei Yamamoto, Yutaka Yoshikawa, Matsumi Doe, Yoshitane Kojima, Hiromu Sakurai, Hiroko Hashimoto, Naemi M. Kajiwara
- Journal Title
  
  Bull. Chem. Soc. Jpn. 78(6)
  
  Pages: 1077-1081
- NAID
  10016143280
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] A family of insulinomimetic zinc(II) complexes of amino ligands with Zn(Nn) (n=3 and 4) coordination modes2005
- Author(s)
  Yutaka Yoshikawa, Mayuko Kondo, Hiromu Sakurai, Yoshitane Kojima
- Journal Title
  
  J. Inorg. Biochem. 99(7)
  
  Pages: 1497-1503
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Synthesis, structure, and in vitro and in vivo insulinomimetic activities of the zinc(II)-6-ethylpicolinate complex2005
- Author(s)
  Yoshitane Kojima
- Journal Title
  
  Bull. Chem. Soc. Jpn. 78・3
  
  Pages: 451-455
- NAID
  10015431988
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] In vitro alpha-glucosidase inhibitory effect of Zn(II) complex with 6-methyl-2-picolinmethylamide2005
- Author(s)
  Eriko Ueda, Yutaka Yoshikawa, Hiromu Sakurai, Yoshitane Kojima, Naemi M. Kajiwara
- Journal Title
  
  Chem. Pharm. Bull. 53(4)
  
  Pages: 451-452
- NAID
  10016653321
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Synthesis, Structure, and in vitro and in vivo insulinomimetic activities of the zinc(II)-6-ethylpicolinate complex2005
- Author(s)
  Yoshitane Kojima
- Journal Title
  
  Bull.Chem.Soc.Jap. 78(3)
  
  Pages: 451-455
- NAID
  10015431988
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Insulinomimetic activity of zinc(II) complexes with halogenated picolinic acids2004
- Author(s)
  Shuhei Yamamoto, Yutaka Yoshikawa, Eriko Ueda, Tetsushi Yamashita, Naemi M. Kajiwara, Hiromu Sakurai, Yoshitane Kojima
- Journal Title
  
  Biomed. Res. Trace Elements 15(1)
  
  Pages: 85-87
- NAID
  10028287164
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] New bioactive zinc(II) complexes with peptides and their derivatives : synthesis, structure, and in vitro insulinomimetic activity2004
- Author(s)
  Eriko Ueda, Yutaka Yoshikawa, Noriko Kishimoto, Makoto Tadokoro, Hiromu Sakurai, Naemi M. Kajiwara, Yoshitane Kojima
- Journal Title
  
  Bull. Chem. Soc. Jpn. 77(5)
  
  Pages: 981-986
- NAID
  10012940689
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] The action mechanism of zinc(II) complexes with insulinomimetic activity in rat adipocytes2004
- Author(s)
  Yutaka Yoshikawa, Eriko Ueda, Yoshitane Kojima, Hiromu Sakurai
- Journal Title
  
  Life Sci. 75(6)
  
  Pages: 741-751
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] A new insulin-mimetic bis(allixinato)zinc(II) complex : structure-activity relationship of zinc(II) complexes2004
- Author(s)
  Yusuke Adachi, Jiro Yoshida, Yukihiro Kodera, Akira Kato, Yutaka Yoshikawa, Yoshitane Kojima, Hiromu Sakurai
- Journal Title
  
  J. Biol. Inorg. Chem. 9(7)
  
  Pages: 885-893
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003

1. SAKURAI Hiromu (30065916)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. YAHAGIHARA Naohisa (40230271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TSUKUBE Hiroshi (00144725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YASUI Hiroyuki (20278443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YOSHIKAWA Yutaka (20388028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. HIROMURA Makoto (30411036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ADACHI Hidenari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOJIMA Yoshitane 小嶋 良種

Research Projects

Research Products

Co-Researchers

Development of Metal Complexes with Antidialetic Effect

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Syntheses of Vanadium Complexes with Bis-amino Acid Derivatives and Evaluations of their Insulin-like ActivitiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アミノ酸の側鎖官能基のみが銅(II)イオンに配位したガラクトースオキシダーゼモデルPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inhibition mode and inhibitory effect in vivo to aipha-glucosidase of Zn(II) complex with picolinamide derivatives2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Zinc(II) complexes with allixin-derivatives as oral therapeutics for type 2 diabetes2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Synthesis, structure, and in vitro and in vivo insulinomimetic activities of the zinc(II)-6-ethylpicolinate complex.2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Synthesis, structure, and in vitro and in vivo insulinomimetic activities of the zinc(II)-6-ethylpicolinate complex2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Antidiabetic activity of Zn(II) complexes with a derivative of L-glutamine2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] A family of insulinomimetic zinc(II) complexes of amino ligands with Zn(Nn) (n=3 and 4) coordination modes2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Synthesis, structure, and in vitro and in vivo insulinomimetic activities of the zinc(II)-6-ethylpicolinate complex2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] In vitro alpha-glucosidase inhibitory effect of Zn(II) complex with 6-methyl-2-picolinmethylamide2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Synthesis, Structure, and in vitro and in vivo insulinomimetic activities of the zinc(II)-6-ethylpicolinate complex2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Insulinomimetic activity of zinc(II) complexes with halogenated picolinic acids2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] New bioactive zinc(II) complexes with peptides and their derivatives : synthesis, structure, and in vitro insulinomimetic activity2004

Author(s)

KOJIMA Yoshitane 小嶋良種