IMANAGA Issei 今永一成

Researcher Number	40078613
External Links
Affiliation (based on the past Project Information) *help	2005 – 2006: 福岡大学, 医学部, 教授 1988 – 1998: 福岡大学, 医学部, 教授 1994: 福岡大学, 医学部・, 教授
Review Section/Research Field	Principal Investigator Neurophysiology and muscle physiology / General physiology Except Principal Investigator 神経・脳内生理学 / Neurophysiology and muscle physiology
Keywords	Principal Investigator cardiac muscle / PKC / gap junction / c-AMP / ギャップ結合 / 興奮伝導 / 心筋 / excitation conduction / ventricular fibrillation / remodeling … More / connexin 43 / cardiac muscle cell / 心室細動 / リモデリング / コネキシン43 / ギヤップ結合 / 心筋細胞 / acidosis / Ca-overload / PKA inhibiotr / hypoxia / gap juntion conductance / 蛋白キナーゼA抑制剤 / チャネル燐酸化 / 心筋ギャップ結合 / ヘプタノール / 細胞内Ca^<2+>、H^+ / 低酸素下不整脈 / PKA / C-AMP / ギャップ結合チャネル / 細胞内燐酸化 / 細胞内Ca過負荷 / PKA抑制剤 / 低酸素 / ギャップ結合電気的抵抗 / リエントリー / 不整脈 / ネクサス抵抗 / heptanol / calmodulin inhibitor / nexus resistance / gap junction resistance … More Except Principal Investigator Ca^<2+> / ATP / 副腎髄質細胞 / muscarinic receptor / ムスカリン受容体 / モルモット / 心筋 / ミトコンドリア / 燐酸化 / Excitable cells / Na channels / Planar lipid bilayer / Naチャネル / 興奮性細胞 / Naチャンネル / 人工脂質膜法 / depolarization / Ca / mitochondria / cation channel / anoxia / chromaffin cell / シアン化合物 / シアン / 脱分極 / Caイオン / カチオンチャネル / 酸素欠乏 / Mg^<2+>-dependent phosphatase / dephosphorylation / phosphorylation / G protein / nonselective cation channel / adrenal chromaffin cell / Mg^<2+>依存性脱燐酸化酵素 / 脱燐酸化 / G蛋白 / 非選択的カチオンチャネル / single channel currents / sarcoplasmic reticulum / cardiac muscle / ionic channels / 単一イオンチャネル電流 / 単一イオンチャネル / 小胞体 / イオンチャネル / beta adrenergic stimulation / Ca^<2+> channel / A channel / cardiac cell / 不活性化 / TEA / 4-aminopyridine / 一過性外向き電流 / A電流 / beta受容体刺激 / Caチャネル / β受容体刺激 / Aチャネル / 加水分解 / ATPase / 脱燐酸化酵素 / 内向き整流Kチャネル Less

Significance of an activation of PKC in remodeling of connexin 43 of the cardiac gap junction channelPrincipal Investigator
- Principal Investigator
  
  IMANAGA Issei
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Fukuoka University
Effects of cyanide on a cation channel and catecholamine secretion
- Principal Investigator
  
  INOUE Masumi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Fukuoka University
内向き整流Kチャネルの機能維持におけるATPの役割、及び関与するATP産生機構
- Principal Investigator
  
  井上真澄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Fukuoka University
Study on regulatory mechanisms of gap junction conductance of cardiac musclePrincipal Investigator
- Principal Investigator
  
  IMANAGA Issei
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Fukuoka University
Mechanisms for activation and deactivation of muscarinic receptor-regulated channel.
- Principal Investigator
  
  MASUMI Inoue
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Fukuoka University
Modification mechanisms of single ionic channel currents from cardiac sarcoplasmic reticulum and mitochondria by physiologically active substances.
- Principal Investigator
  
  UEHARA Akira
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Fukuoka University
心筋ネクサスのキネティクスと興奮伝導における役割に関する電気生理学的研究Principal Investigator
- Principal Investigator
  
  今永一成
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Fukuoka University
Physiological and pharmacological properties of A-like current evoked in Ca free solution and their developmental changes
- Principal Investigator
  
  INOUE Masumi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Fukuoka University
心筋ネクサスのキネティクスと興奮伝導における役割に関する電気生理学的研究Principal Investigator
- Principal Investigator
  
  今永一成
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Fukuoka University
心筋ネクサスのキネティクスと興奮伝導における役割に関する電気生理学的研究Principal Investigator
- Principal Investigator
  
  今永一成
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Fukuoka University
Comparison of Sodium Channel Currents Between Various Excitable Cells by Planar Lipid Bilayer and Patch Clamp Methods
- Principal Investigator
  
  UEHARA Akira
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Fukuoka University

All 2007 2006 2005

All Journal Article Book

[Book] Gap Junctionと不整脈Medical Topics Series不整脈20072007
- Author(s)
  今永一成
- Publisher
  メディカルレビュー社(印刷中)
- Data Source
  KAKENHI-PROJECT-17500280
[Book] Gap Junctionと不整脈 Medical Topics Series 不整脈 20072007
- Author(s)
  今永一成
- Publisher
  メディカルレビュー社(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] PKC-Induced Remodeling of cardiac gap junction connexin 43 and aahythmogenesis2006
- Author(s)
  Imanaga I, et al.
- Journal Title
  
  Chinese J Pathophysiol 22(13)
  
  Pages: 244-244
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] PKC-Induced Remodeling of cardiac gap junction connexin 43 and aahythmogenesis2006
- Author(s)
  Imanaga I et al.
- Journal Title
  
  Chinese J Pathophysiol 22(13)
  
  Pages: 244-244
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] Degradation of connexin43 induced by phosphorylation and dephosphorylation2006
- Author(s)
  Imanaga I et al.
- Journal Title
  
  J Physiol Sci 56, Suppl.S29
- NAID
  130005448066
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] 心筋 gap junction connexin 43のremodelingとarrhythmogenesis2006
- Author(s)
  今永一成ら
- Journal Title
  
  心電図 26
  
  Pages: 394-395
- NAID
  10018659473
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] Degradation of connexin 43 induced by phosphorylation and dephosphorylation2006
- Author(s)
  Imanaga I, et al.
- Journal Title
  
  J Physiol Sci 56
- NAID
  130005448066
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] Degradation of connexin43 induced by phosphorylation and dephosphorylation2006
- Author(s)
  Imanaga I et al.
- Journal Title
  
  J Physiol Sci 56
- NAID
  130005448066
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] 心筋gap junction connexin 43の remodelingとarrhythmogenesis2006
- Author(s)
  今永一成ら
- Journal Title
  
  心電図 26
  
  Pages: 394-395
- NAID
  10018659473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] 心筋 Gap junction connexin43(Cx43)のどのようなremodelingが心筋細動発現に関与するか2006
- Author(s)
  今永一成ら
- Journal Title
  
  日本病態生理学会雑誌 15(2)
  
  Pages: 36-36
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] 心筋 gap junction connexin 43 の remodeling と arrhythmogenesis2006
- Author(s)
  今永一成ら
- Journal Title
  
  心電図 26
  
  Pages: 394-395
- NAID
  10018659473
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] Degradation of connexin43 induced by phosphorylation and dephosphorylation2006
- Author(s)
  I.Imanaga
- Journal Title
  
  Journal of Physiological Sciences 56・Suppl.
- NAID
  130005448066
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] 心筋Gap junction connexin43(Cx43)のどのようなremodelingが心筋細動発現に関与するか2006
- Author(s)
  今永一成ら
- Journal Title
  
  日本病態生理学会雑誌 15(2)
  
  Pages: 36-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] PKC-Induced Remodeling of cardiac gap junction connexin 43 and arrhythmogenesis2006
- Author(s)
  Imanaga I et al.
- Journal Title
  
  Chinese J Pathophysiol 22(13)
  
  Pages: 244-244
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] The remodeling of the gap junction makes the heart susceptible to arrhythmias2005
- Author(s)
  I.Imanaga
- Journal Title
  
  The 5^<th>. Japan-Korea Joint Symposium on Brain Sciences, and Cardiac and Smooth Muscles abstract
  
  Pages: 27-27
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] 心筋gap junction connexin43のremodelingと arrhythmogenesis2005
- Author(s)
  今永一成ら
- Journal Title
  
  日本臨床生理学会雑誌 35, Suppl87
- NAID
  10018659473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] 心筋connexin43のremodelingとarrhythmogenesis2005
- Author(s)
  今永一成
- Journal Title
  
  日本臨床生理学雑誌 35・Suppl
  
  Pages: 87-87
- Data Source
  KAKENHI-PROJECT-17500280
[Journal Article] 心筋connexin43のremodelingとarrhythmogenesis2005
- Author(s)
  今永一成ら
- Journal Title
  
  日本臨床生理学会雑誌 35
  
  Pages: 87-87
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500280

1. INOUE Masumi (40223276)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. SAKAMOTO Yasuji (30078761)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 矢野晶子 (00279283)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. UEHARA Akira (60140745)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OGAWA Kouichi (60078780)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. OGATA Shigenori (30131816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MATSUSHITA Misao (00165812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HAI Lin (00341438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IMANAGA Issei 今永 一成

Research Projects

Research Products

Co-Researchers

Significance of an activation of PKC in remodeling of connexin 43 of the cardiac gap junction channelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of cyanide on a cation channel and catecholamine secretion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

内向き整流Kチャネルの機能維持におけるATPの役割、及び関与するATP産生機構

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on regulatory mechanisms of gap junction conductance of cardiac musclePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms for activation and deactivation of muscarinic receptor-regulated channel.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modification mechanisms of single ionic channel currents from cardiac sarcoplasmic reticulum and mitochondria by physiologically active substances.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋ネクサスのキネティクスと興奮伝導における役割に関する電気生理学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Physiological and pharmacological properties of A-like current evoked in Ca free solution and their developmental changes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋ネクサスのキネティクスと興奮伝導における役割に関する電気生理学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

心筋ネクサスのキネティクスと興奮伝導における役割に関する電気生理学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Comparison of Sodium Channel Currents Between Various Excitable Cells by Planar Lipid Bilayer and Patch Clamp Methods

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Gap Junctionと不整脈Medical Topics Series不整脈20072007

Author(s)

Publisher

Data Source

[Book] Gap Junctionと不整脈 Medical Topics Series 不整脈 20072007

Author(s)

Publisher

Description

Data Source

[Journal Article] PKC-Induced Remodeling of cardiac gap junction connexin 43 and aahythmogenesis2006

Author(s)

Journal Title

Data Source

IMANAGA Issei 今永一成

[Journal Article] 心筋Gap junction connexin43(Cx43)のどのようなremodelingが心筋細動発現に関与するか2006