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YAMAMOTO Kenji  山本 健二

ORCIDConnect your ORCID iD *help
… Alternative Names

山本 建二  ヤマモト ケンジ

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Researcher Number 40091326
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2012: 九州大学, 薬学研究院, 特命教授
2011 – 2012: 九州大学, 大学院・薬学研究院, 特命教授
2008 – 2010: Kyushu University, 大学院・薬学研究院, 特任教授
2009: Kyushu University, 薬学研究院, 特任教授
2008: 九州大学, 大学院・薬学研究院, 教授 … More
2007: Kyushu University, 大学院・歯学研究院, 助教
2007: Nagasaki University, Department of Pharmacology Graduate School of Dental Science, Professor
2006: 九州大学, 歯学研究院, 教授
2005: 九州大学, 大学院歯学研究院, 教授
2000 – 2005: KYUSHU UNIVERSITY, GRADUATE SCHOOL OF DENTAL SCIENCE, PROFESSOR, 大学院・歯学研究院, 教授
1989 – 1999: 九州大学, 歯学部, 教授
1987 – 1988: 長崎大学, 歯学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Functional basic dentistry / Functional basic dentistry / Biological Sciences
Except Principal Investigator
Functional basic dentistry / Functional basic dentistry / Conservative dentistry
Keywords
Principal Investigator
Porphyromonas gingivalis / カテプシンE / Arg-gingipain / Lys-gingipain / 歯周病 / アスパラギン酸プロテアーゼ / プロセシング / カテプシンD / システインプロテアーゼ / プロテアーゼ … More / ジンジバリス菌 / 生合成 / 歯学 / ジンジパイン / カテプシン / 細胞内アスパラギン酸プロテアーゼ / ミクログリア / 胸腺細胞 / 歯周病原性プロテアーゼ / 生体防御 / 蛋白質分解 / エンドソーム・リソソーム系 / 感染症 / 癌 / 免疫学 / 薬理学 / 病原性プロテアーゼ / 歯周疾患 / 歯肉溝滲出液 / Periodontal disease / periodontal disease / 病原性因子 / 歯周病治療薬 / 細胞内輸送 / フレンド細胞 / CHO細胞 / グラム陰性嫌気性細菌 / ノックアウト / エンドソーム / リソソーム系 / ノックアウトマウス / オートファジー / 病原性細菌 / タンパク分解酵素 / 歯周組織の破壊 / 臨床評価法 / 歯周病原性菌 / プロテア-ゼ / CATHEPSIN B / CATHEPSIN L / cysteine proteinases / 歯周病原菌 / proteinases / cathepsins / virulence factors / カプテシンD / 活性化機構 / マウス白血病フレンド細胞 / チャイニーズハムスター卵巣細胞 / 選別輸送機構 / 蛋白分解システム / 酵素欠損変異体 / Prophyromonas gingivalis / マクロファージ / タンパク質分解 / オートオファジー / エンドソーム・リソソーム / 蛋白質分解酵素 / 神経変性疾患 / 品質管理 / 神経系 / バッテン病 / リソーム系 / 蛋白質 / トランスレーショナルリサーチ / 発現制御 / 分子標的治療薬 / 早期診断キット / 蛋白質分子進化技術 / 酵素 / 細菌 / 薬学 / 唾液 / ラクトフェリン / 抗菌作用 / 歯周組識の破壊 / 歯周組織の破壊機構 / 実験的歯肉炎 / 臨床パラメ-タ / Periodontal tissue / Proteinases / 歯周組織破壊 / 顆粒球セリンプロテア-ゼ / カテプシンG / PERIODONTITIS / GINGIVITIS / CATHEPSIN H / CATHEPSIN G / MEDULLASIN / GINGIVAL CREVICULAR FLUID / リソソーム膜 / 破骨細胞 / 骨吸収 / 免疫組織学 / リソゾ-ム膜タンバン質 / OSTEOCLAST / BONE RESORPTION / LYSOSOMAL MEMBRANE PROTEIN / CATHEPSIN D / 病原因子 / Argingipain / 病原性システインプロテアーゼ / 遺伝子のクローニング / 蛋白質一次構造 / 機能と病態 / periodontal pathogen / a virulence factor / cloning / primary structures / 治療薬の開発 / 臨床評価法の確立 / clinical parameter / drug design / oral bacterium / Porphyromonase gingivalis / 病原性発現機序 / 病原菌プロテアーゼ / oral anaerobic bacterium / crysteine proteinase / 新規阻害物質 / 放線菌 / 歯周菌 / Agr-gingipain / インヒビター / プロテアーゼインヒビター / 歯周病ワクチン / periodontitis / pathogen / gram-negative anaerobic bacterium / porphyromonas gingivalis / novel inhibitors / 生体防御系 / グラム陰性嫌気性細胞 / 宿主細胞傷害活性 / プロテアーゼ機能 / 生存戦略 / アミノ酸・ヘム獲得 / グラム陰性嫌気細菌 / gingipains / aspartic proteinases / host defense mechanisms / 特異的阻害剤 / Virulence factor / Protease / Gingipains / Specific inhibitor / Drugs for periodontal disease / 免疫応答 / Infectious disease / Tumor / Dentistry / Immunology / Pharmacology / Proteases … More
Except Principal Investigator
カテプシンE / カテプシンD / プロテアーゼ / ミクログリア / 歯周病 / Bcl-2 / LPS / カテプシンB / カテプシンH / メダラシン / アスパラギン酸プロテアーゼ / 免疫組織化学 / 酵素活性 / 初代培養ミクログリア / エンドソーム / 動脈硬化症 / ジンジパイン / 老化 / PC12細胞 / cathepsin E / microglia / ovalbumin / Porphyromonas gingivalis / リソゾ-ム性酵素 / 細胞内プロテア-ゼ / プロテア-ゼ / 歯周疾患 / 歯周組織破壊 / 歯周病原性菌 / 好中球 / 歯肉溝滲出液 / P.gingivalis / basic FGF / 分解調節 / 咬筋運動ニューロン / 骨改造現象 / 骨芽細胞 / 破骨細胞 / 蛋白質分解酵素 / ライソゾーム膜糖蛋白質 / 顔面神経核 / 逆行性変性 / DNA損傷 / 生合成 / プロセッシング / 糖鎖 / 細菌感染 / 糖尿病 / 動脈硬化 / 生活習慣病 / インスリン抵抗性 / P. gingivalis / P.gingvalis / ジンジバイン / 三叉神経節神経細胞 / リソソーム系蛋白分解機構 / カテプシン群 / 免疫組織 / 免疫電顕 / ラット / CATHEPSINS / TRIGEMINAL GANGLION / AGING / LYSOSOME / PHAGOCYTOSIS / ポルフィロモナス・ジンジバリス / ポルフィロモナス ジンジバリス / PORPHYROMONAS GINGIVALIS / PROTEINASE / PERIODONTAL DISEASES / 固形飼料 / 粉末飼料 / 海馬切片 / 咀嚼運動 / ルシファーイエロ- / 痴呆症 / 膜電位 / シナプス長期増強 / 膜抵抗 / pelet food / powder food / long-term potentiation / hipopcampus / field potential / GABA / glutamatr / pyramidal cell / 細胞内アスパラギン酸プロテアーゼ / 神経細胞死 / カスパーゼ / PC19細胞 / 細胞死モデル / 神経細胞 / 遺伝子導入 / 分化誘導 / intracellular aspartic proteinase / neuronal death / aging / PC12 cells / caspase / IFN-γ / ペプスタチンA / カスパーゼ3 / アポトーシス / INF-γ / ネクローシス / イムノブロット / ルミノール反応 / CATHEPSIN E / MICROGLIA / INTERFERON-gamma / LIPOPOLYSACCHARIDE / PEPSTATIN A / PC12 CELL / CASPASE-3 / BCL-2 / APOPTOSIS / カテプシンンD / 抗原提示 / 抗原ペプチド / インバリアント鎖 / カテプシンD欠損マウス / カテプシン阻害剤 / pepstatin A / インターロイキン-2 / インターフェロン-γ / cathepsin D / antigen presentation / antigenic peptide / invaliant chain / cathepsin D-deficient mice / 生体応答 / 複合体 / ジンジバリス菌 / マクロファージ / periodontal disease / biological response / Protease / atherosclerosis / gingipains / molecular complex / 上皮細胞 / カテプシン / リソソーム / ノックアウトマウス / cathepsin / endosomes / lysosomes / epithelial cells / deficient mice / skin / gingiva / protease / リソゾーム性酵素 / カテプシンL / リソゾーム酵素 / 抗炎症剤 / Lysosomal proteinases / Cathepsin B / Cathepsin H / Cathepsin D / Cathepsin E Less
  • Research Projects

    (39 results)
  • Research Products

    (179 results)
  • Co-Researchers

    (28 People)
  •  Relationship between periodontal disease and systemic diseases: molecular mechanisms and novel therapy discoveryPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  蛋白質高速分子進化技術による歯周病の分子標的治療薬及び早期診断キットの開発Principal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Protease-mediated regulation of host immune system and application as therapeutic targetsPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Experimental analysis of the correlation between periodontal disease and insulin resistance

    • Principal Investigator
      TSUKUBA Tomoko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Function of endo-lysosomal proteinases in epithelial cells

    • Principal Investigator
      TSUKUBA Takayuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
      Kyushu University
  •  生体防御系におけるプロテアーゼの機能解析Principal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Examination of biological response to Porphyromonas gingivalis infection.

    • Principal Investigator
      TSUKUBA Tomoko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  Molecular basis of host immune responses to periodontal diseasePrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  歯周病における免疫制御系プロテアーゼの機能解析Principal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  ESTABLISHMENT OF A CLINICAL TREATMENT SYSTEM FOR PERIODONTAL DISEASEPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  神経系におけるオートファジー・リソソームシステムPrincipal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  エンドソーム・リソソーム系蛋白分解機構におけるカテプシンEの役割Principal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  MOLECULAR BASIS OF PROTEINASE FUNCTION IN PROGRESSION OF PERIODONTAL DISEASESPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  Involvement of cathepsin E in exogenous antigen processing in primary cultured microglia

    • Principal Investigator
      NAKANISHI Hiroshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  エンドソーム・リソソーム系蛋白分解機構におけるカテプシンEの役割Principal Investigator

    • Principal Investigator
      山本 建二
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  カテプシンEの生合成と細胞内輸送および局在化機構の解析Principal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  歯周病原菌における蛋白分解システムとその異常の分子レベル解析Principal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  DESIGN AND DEVELOPMENT OF THERAPEUTIC AGENTS OF ADULT PERIODONTITIS THAT INHIBIT ARG-GINGIPAIN PRODUCED BY PORPHYROMONAS GINGIVALISPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  Effect of overexpression of cathepsin E and Bcl-2 on neuronal death

    • Principal Investigator
      HORI Nobuaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  EXPRESSION AND FUNCTION OF CATHEPSIN E IN ACTIVATED MICROGLIA FOLLOWING FACIAL NERVE INJURY

    • Principal Investigator
      NAKANISHI Hiroshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  細胞内アスパラギン酸プロテアーゼの機能構造形成と細胞機能制御Principal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  顔面神経切断に伴って増殖する反応性ミクログリアにおけるカテプシンEの性状解析

    • Principal Investigator
      中西 博
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  ROLES OF PATHOGENIC PROTEINASES IN PERIODONTAL DISEASEPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  骨吸収開始時期における骨細胞および骨芽細胞由来の調節因子の解析

    • Principal Investigator
      AKAMINE Akifumi
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Kyushu University
  •  DNA断片化ならびに細胞内プロテアーゼの動態を指標として逆行性神経変性の検討

    • Principal Investigator
      中西 博
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  GENETIC AND BIOCHEMICAL STUDY ABOUT FUNCTION AND SECRETION MECHANISM OF EXTRACELLULAR PROTEINASES OF PERIODONTOPATHOGENIC MICROORGANISMS

    • Principal Investigator
      NAKAYAMA Koji
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  Effects of mechanical loads of feeding on the physiological development of a central nervous system.

    • Principal Investigator
      HORI Nobuaki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  細胞内アスパラギン酸プロテアーゼの選別と輸送機構Principal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  アスパラギン酸プロテアーゼによる生理活性ペプチドの分解を介した三叉神経機能の調節

    • Principal Investigator
      中西 博
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Structures and Functions of Periodontopathogenic ProteinasesPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  DEVELOPMENT OF A NEW CLINICAL PARAMETER FOR ASSESSMENT OF PROGRESSIVE PERIODONTAL DIDEASE AND ITS THERAPEUTIC AND PREVENTIVE DRUGSPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUShU UNIVERSITY
  •  歯周病原性プロテアーゼの機能と病態

    • Principal Investigator
      KAMATA Osamu
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  PHYSIOLOGICAL AND PATHOLOGICAL STUDIES OF PROTEINASES IN THE RAT TRIGEMINAL GANGLION CELLS

    • Principal Investigator
      NAKANISHI Hiroshi Ph.D.
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  ROLES OF PROTEOLYTIC ENZYMES AND LYSOSOMAL MEMBRANE PROTEINS IN BONE RESORBING PROCESSPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  THE DEVELOPMENT OF A NEW CLINICAL PARAMETER FOR DIAGNOSIS OF PERIODONTAL DISEASES AND THE NEW DRUG DESIGNPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  硬組織に由来する細胞の機能発現とリソゾ-ム性酵素の役割に関する実験薬理学的研究

    • Principal Investigator
      KATO Yuzo
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  The Pole of Proteinases in Periodontal Tissue BreakdownPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  唾液内ラクトフェリンの抗菌機序と歯科疾患適用への基礎的研究Principal Investigator

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Roles of lysosomal proteinases in the patho-physiological changes of hard tissues.

    • Principal Investigator
      KATO Yuzo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University

All 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001

All Journal Article Presentation Book Patent

  • [Book] 現代歯科薬理学(第4版)2005

    • Author(s)
      山本 健二
    • Total Pages
      548
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-16659514
  • [Book] 現代歯科薬理学(第4版)2005

    • Author(s)
      山本 健二
    • Total Pages
      548
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-15209062
  • [Book] 実験医学 22, 213-2192004

    • Author(s)
      山本健二, 岩田淳一
    • Total Pages
      219
    • Data Source
      KAKENHI-PROJECT-15209062
  • [Book] 実験医学 222004

    • Author(s)
      山本健二
    • Publisher
      洋土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209062
  • [Book] 実験医学2004

    • Author(s)
      山本健二, 岩田淳一
    • Total Pages
      219
    • Data Source
      KAKENHI-PROJECT-16659514
  • [Book] 実験医学 22,213-2192004

    • Author(s)
      山本健二, 岩田淳一
    • Publisher
      (印刷中)
    • Data Source
      KAKENHI-PROJECT-12146203
  • [Book] 実験医学 22, 213-2192004

    • Author(s)
      山本健二, 岩田淳一
    • Total Pages
      219
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Book] 実験医学 第22巻2004

    • Author(s)
      山本健二
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Book] 日本薬理学会誌 1222003

    • Author(s)
      山本健二
    • Publisher
      日本薬理学会
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209062
  • [Book] 臨床検査 472003

    • Author(s)
      山本健二
    • Publisher
      医学書院
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209062
  • [Book] 臨床検査 第47巻2003

    • Author(s)
      山本健二
    • Publisher
      医学事院
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Book] 化学と生物 第40巻2002

    • Author(s)
      山本健二
    • Publisher
      学会出版センター
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Book] タンパク質分解の不思議2001

    • Author(s)
      山本健二
    • Publisher
      クバクロ
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Book] 蛋白質核酸酵素 第46巻2001

    • Author(s)
      山本健二
    • Publisher
      共立出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Book] 医学のあゆみ 第198巻2001

    • Author(s)
      山本健二
    • Publisher
      医歯薬出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Journal Article] Effect of a Japanese energy healing method known as Johrei on viability and proliferation of cultured cancer cells in vitro2012

    • Author(s)
      Abe K, Ichinomiya R, Kanai T, Yamamoto K
    • Journal Title

      J Alternat. Comlement. Med

      Volume: 18(3) Pages: 221-228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Emerging roles of cathepsin E in host defense mechanisms2012

    • Author(s)
      Yamamoto K, Kawakubo T, Yasukochi A, Tsukuba T
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1824 Pages: 105-112

    • NAID

      120005324431

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Emerging roles of cathepsin E in host defense mechanism2012

    • Author(s)
      Yamamoto, K., et al
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1824 Pages: 105-112

    • DOI

      10.1016/j.bbapap.2011.05.022

    • NAID

      120005324431

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791790, KAKENHI-PROJECT-22390350
  • [Journal Article] Role of the transcription factor Sp1 in regulating the expression of the murine cathepsin E gene.2012

    • Author(s)
      Okamoto K
    • Journal Title

      J. Biochem.

      Volume: 151 Pages: 221-228

    • DOI

      10.1093/jb/mvr135

    • NAID

      10031166065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592369, KAKENHI-PROJECT-22592086, KAKENHI-PROJECT-24659840, KAKENHI-PROJECT-22390350
  • [Journal Article] Role of the transcription factor Sp1 in regulating the expression of the murine cathepsin E gene2012

    • Author(s)
      Okamoto K, Okamoto Y, Kawakubo T, Iwata J, Yasuda Y, Tsukuba T, Yamamoto K
    • Journal Title

      J Biochem.

      Volume: 151 Pages: 263-272

    • NAID

      10031166065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Role of the transcription factor Sp1 in regulating the expression of the murine cathepsin E gene2012

    • Author(s)
      Okamoto K, Okamoto Y, Kawakubo T, Iwata J, Yasuda Y, Tsukuba T, Yamamoto K
    • Journal Title

      J Biochem

      Volume: 151(3) Pages: 263-272

    • NAID

      10031166065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Cathepsin E is critical for the proper trafficking of both intracellular membrane and cell surface proteins2012

    • Author(s)
      Tsukuba T, Okamoto K, Yamamoto K
    • Journal Title

      J. Oral Biosci

      Volume: 54 (1) Pages: 48-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Cathepsin E is critical for the proper trafficking of both intracellular membrane and cell surface proteins2012

    • Author(s)
      Tsukuba T, Okamoto K, Yamamoto K.
    • Journal Title

      J. Oral Biosci.

      Volume: 54 Pages: 48-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Cathepsin E is critical for the proper trafficking of both intracellular membrane and cell surface proteins2012

    • Author(s)
      Tsukuba T, Okamoto K, Yamamoto K
    • Journal Title

      J.Oral Biosci.

      Volume: 54 Pages: 48-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Cathepsin E as a potent anticancer protease.2011

    • Author(s)
      Kawakubo T, Yasukochi A, Nakamura S, Yamamoto K.
    • Journal Title

      J.Oral Biosci.

      Volume: 53(印刷中)

    • NAID

      10028222723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Emerging roles of cathepsin E in host defense mechanisms2011

    • Author(s)
      Yamamoto K, Kawakubo T, Yasukochi A, Tsukuba T.
    • Journal Title

      Biochim.Biophys.Acta

      Volume: (印刷中)

    • NAID

      120005324431

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Effect of a Japanese energy healing method known as Johrei on viability and proliferation of cultured cancer cells in vitro2011

    • Author(s)
      Abe K, Ichinomiya R, Kanai T, Yamamoto K
    • Journal Title

      J Alternat.Comlement.Med.

      Volume: 18 Pages: 221-228

    • DOI

      10.1089/acm.2011.0467

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] The role of cathepsin E in terminal differentiation of keratinocytes2011

    • Author(s)
      Kawakubo T, Yasukochi A, Okamoto K, Okamoto Y, Nakamura S, Yamamoto K
    • Journal Title

      Biol. Chem

      Volume: 392 Pages: 571-583

    • NAID

      120005007885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Cathepsin E as a potent anticancer protease2011

    • Author(s)
      Kawakubo T, Yasukochi A, Nakamura S, Yamamoto K
    • Journal Title

      J. Oral Biosci

      Volume: 53 (2) Pages: 126-136

    • NAID

      10028222723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Cathepsin E as a potent anticancer protease2011

    • Author(s)
      Kawakubo T, Yasukochi A, Nakamura S, Yamamoto K
    • Journal Title

      J.Oral Biosci.

      Volume: 53 Pages: 126-136

    • NAID

      10028222723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Peptide aptamer-based ELISA-like system for detection of cathepsin E in tissues and plasma2011

    • Author(s)
      Kitamura K, Biyani M, Futakami M, Ueno-Tsuji S, Suzuki M, Kawakubo T, Yamamoto K, Nishigaki K
    • Journal Title

      J.Mol.Biomark.Diagn.

      Volume: 2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] The role of cathepsin E in terminal differentiation of keratinocytes2011

    • Author(s)
      Kawakubo T
    • Journal Title

      Biol Chem.

      Volume: 392 Pages: 571-583

    • DOI

      10.1515/bc.2011.060

    • NAID

      120005007885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592369, KAKENHI-PROJECT-22791790, KAKENHI-PROJECT-22390350
  • [Journal Article] Peptide aptamer-based ELISA-like system for detection of cathepsin E in tissues and plasma2011

    • Author(s)
      Kitamura, K., et al
    • Journal Title

      J. Mol. Biomark. Diagn

      Volume: 2 Pages: 104-104

    • DOI

      10.4172/2155-9929.1000104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791790, KAKENHI-PROJECT-22390350
  • [Journal Article] In vitro selection of cathepsin E-activity-enhancing peptide aptamers at neutral pH2011

    • Author(s)
      Biyani M, Futakami M, Kitamura K, Kawakubo T, Suzuki M, Yamamoto K, Nishigaki K
    • Journal Title

      Int.J.Pep.

      Volume: 2011 Pages: 1-8

    • DOI

      10.1155/2011/834525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] The inhibition of RANKL/RANK signaling by osteoprotegerin suppresses bone invasion by oral squamous cell carcinoma cells2011

    • Author(s)
      Shin M, et al
    • Journal Title

      Carcinogenesis

      Volume: 32 Pages: 1634-1640

    • DOI

      10.1093/carcin/bgr198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592247, KAKENHI-PROJECT-22791795, KAKENHI-PROJECT-22390350
  • [Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis.2010

    • Author(s)
      Yasukochi A, Kawakubo T, Nakamura S, Yamamoto K.
    • Journal Title

      Biol Chem (in press)

    • NAID

      120006900038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis2010

    • Author(s)
      Yasukouchi A, Kawakubo T, Nakamura S, Yamamoto K
    • Journal Title

      Biol. Chem

      Volume: 391 Pages: 947-958

    • NAID

      120006900038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Cathepsin E enhances anticancer activity of doxorubicin on human prostatecancer cells showing resistance to TRAIL-mediated apoptosis2010

    • Author(s)
      Yasukochi A, Kawakubo T, Nakamura S, Yamamoto K
    • Journal Title

      Biol.Chem.

      Volume: 391 Pages: 947-958

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] 大学改革後の歩みと国際競争力2010

    • Author(s)
      山本健二
    • Journal Title

      生化学

      Volume: 81 Pages: 363-363

    • NAID

      10026425747

    • Data Source
      KAKENHI-PROJECT-22390350
  • [Journal Article] Impaired chemotaxis and cell adhesion due to decrease in wide range of cell surface receptors in cathepsin E-deficient macrophages.2009

    • Author(s)
      Tsukuba T, Yanagawa M, Okamoto K, Okamoto Y, Yasuda Y, Nakayama KI, Kadowaki T, Yamamoto K.
    • Journal Title

      J. Biochem. 145(5)

      Pages: 565-573

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Development of systemin in vitro evolution and its application to generation of peptide aptamer-based inhibitors of cathepsin E.2009

    • Author(s)
      Kitamura K, Yoshida C, Kinoshita Y, Kadowaki T, Takahashi Y, Tayama T, Kawakubo T, Naimuddin M, Salimulla M, Nemoto N, Hanada K, Husimi Y, Yamamoto K, Nishigaki K.
    • Journal Title

      J. Mol. Biol. 387

      Pages: 1186-1198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Gene expression of profiling of mammary glands of cathepsin E-deficient mice compared with wild-type littermates.2008

    • Author(s)
      Kawakubo T., Yasukochi A., Tsukuba T., Kadowaki T., Yamamoto K.
    • Journal Title

      Biochimie 90

      Pages: 396-404

    • NAID

      120006900027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] An immunohistochemical study on a unique colocalization relationship between substance P and GABA in the central nucleus of amygdala.2008

    • Author(s)
      Shigematsu, N., Yamamoto, K., Higuchi, S., Fukuda, T.
    • Journal Title

      Brain Res. 1198

      Pages: 55-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mice2008

    • Author(s)
      Shigematsu N, Fukuda T, Yamamoto T, Nishioku T, Yamaguchi T, Himeno M, Nakayama. KI, Tsukuba T, Kadowaki T, Okamoto K, Higuchi S, Yamamoto K.
    • Journal Title

      J Neurochem. 105

      Pages: 1394-1404

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Determination of active site of Lysine-specific cysteine proteinase (Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system2008

    • Author(s)
      Ishida Y, Hu JP, Sakai E, Kadowaki T, Yamamoto K, Tsukuba T, Nakayama K, Okamoto K
    • Journal Title

      Arch. Oral Biol 53

      Pages: 538-544

    • NAID

      120006984583

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592148
  • [Journal Article] Determination of active site of lysine-specific cysteine proteinase(Lys-gingipain)by use of a Porphyromonas gingivalis plasmid system2008

    • Author(s)
      Ishida Y, Hu J, Sakai E, Kadowaki T, Yamamoto K, Tsukuba T, Kato Y, Nakayama K, Okamoto K.
    • Journal Title

      Arch Oral Biol. 53

      Pages: 538-544

    • NAID

      120006984583

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mouse2008

    • Author(s)
      Shigematsu N., Fukuda T., Yamamoto T., Nishioku T., Yamaguchi T., Himeno M., Nakayama K.I., Tsukuba T., Kadowaki T., Okamoto K., Higuchi S., Yamamoto K.
    • Journal Title

      J. Neurochem. 105

      Pages: 1394-1404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Determination of active site of lysine-specific cysteine proteinase(Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system2008

    • Author(s)
      Y, Hu, J, Sakai, E, Kadowaki, T, Yamamoto, K, Tsukuba, T, Kato, Y, Nakayama, K, Okamoto, K
    • Journal Title

      Arch Oral Biol (in press)

    • NAID

      120006984583

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mice2008

    • Author(s)
      Shigematsu, N, Fukuda, T, Yamamoto, T, Nishioku, T, Yamaguchi, T, Himeno, M, Nakayama, KI, Tsukuba, T, Kadowaki, T, Okamoto, K, Higuchi, S, Yamamoto, K
    • Journal Title

      J Neurochem (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mouse2008

    • Author(s)
      Shigematsu N, Fukuda T, Yamamoto T, Nishioku T, Yamaguchi T, Himeno M, Nakayama KI, Tsukuba T, Kadowaki T, Okamoto K, Higuchi S, Yamamoto K.
    • Journal Title

      J. Neurochem 105

      Pages: 1394-1404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592148
  • [Journal Article] Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteolytic Release of Soluble TRAIL from Tumor Cell Surface2008

    • Author(s)
      Kawakubo T, Okamoto K, Iwata J, Shin M, Okamoto Y, Yasukochi A, Nakayama KI, Kadowaki T, Tsukuba T, Yamamoto K.
    • Journal Title

      Cancer Res 67

      Pages: 10869-10878

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592148
  • [Journal Article] Determination of active site of Lysine-specific cysteine proteinase (Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system.2008

    • Author(s)
      Ishida Y., Hu J.P., Sakai E., Kadowaki T., Yamamoto K., Tsukuba T., Nakayama K., Okamoto K.
    • Journal Title

      Arch. Oral Biol. 53(6)

      Pages: 538-544

    • NAID

      120006984583

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Gene expression profiling of mammary elands of cathepsin E-deficient mice compared with wild-type littermates2008

    • Author(s)
      Kawakubo, T, Yasukochi, A, Tsukuba, T, Kadowaki, T, Yamamoto, K
    • Journal Title

      Biochimie 90

      Pages: 396-404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erthrocytes, and inhibition of hemaggelutination by an interdomain regional peptide.2007

    • Author(s)
      Sakai, E., Naito, M., Sato, K., Hotokezaka, H., Kadowaki, T., Kamaguch, A., Yamamoto, K., Okamoto, K., Nakayama, K.
    • Journal Title

      J. Bacteriol. 189

      Pages: 3977-3986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an interdomain regional peptide2007

    • Author(s)
      Sakai, E, Naito, M, Sato, K, Hotokezaka, H, Kadowaki, T, Kamaguchi, A, Yamamoto, K, Okamoto, K, Nakayama, K
    • Journal Title

      J Bacteriol 189

      Pages: 3977-3986

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Role for gingipains in Porphyromonas gingivalis traffic to phagolysosomes and survival in human aortic endothelilal cells.2007

    • Author(s)
      Yamatake, K., Maeda, M., Kadowaki, T., Takii, R., Tsukuba, T., Ueno, T., Kominami, E., Yokota, S., Yamamoto, K.
    • Journal Title

      Infect. Immun. 75

      Pages: 2090-2100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteolytic Release of Soluble TRAIL from Tumor Cell2007

    • Author(s)
      Kawakubo T., Okamoto K., Iwata J., Shin M., Okamoto Y., Yasukochi A., Nakayama K.I., Kadowaki T., Tsukuba T., Yamamoto K.
    • Journal Title

      Surface. Cancer Res. 67

      Pages: 10869-10878

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E2007

    • Author(s)
      Kakehashi H, Nishioku T, Tsukuba T, Kadowaki T, Nakamura S, Yamamoto K.
    • Journal Title

      J Immunol. 179

      Pages: 5728-5737

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Gene expression profiling of mammary glands of cathepsin E-deficient mice compared with wild-type littermates2007

    • Author(s)
      Kawakubo T, Yasukochi A, Tsukuba T, Kadowaki T, Yamamoto K.
    • Journal Title

      Biochimie. 90

      Pages: 396-404

    • NAID

      120006900027

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Selection-by-function : efficient enrichment of cathepsin E inhibitors from a DNA library2007

    • Author(s)
      Naimuddin, M, Kitamura, K, Kinoshita, Y, Honda-Takahashi, Y, Murakami, M, Ito, M, Yamamoto, K, Hanada, K, Husimi, Y, Nishigaki, K
    • Journal Title

      J Mol Recognit 20

      Pages: 58-68

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases2007

    • Author(s)
      Kanaji, S, Tanaka, Y, Sakata, Y, Takeshita, K, Arima, K, Ohta, S, Hansell, EJ, Caffrey, C, Mottram, JC, Lowther, J, Donnelly, S, Stack, C, Kadowaki, T, Yamamoto, K, McKerrow, JH, Dalton, JP, Coombs, GH, Izuhara, K
    • Journal Title

      FEBS Lett 581

      Pages: 4260-4264

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] The role for Gingipains in Porphyromonas gingivalis traffic to phagol ysosomes and survival in human aortic endothelial cells2007

    • Author(s)
      Yamatake K., Maeda M., Kadowaki T., Takii, R., Tsukuba T., Ueno T., Kominami, E., Yokota S., Yamamoto K.
    • Journal Title

      Infect.Immun 75

      Pages: 2090-2100

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingivalis-infected cells2007

    • Author(s)
      Kadowaki, T, Takii, R, Yamatake, K, Kawakubo, T, Tsukuba, T, Yamamoto, K
    • Journal Title

      Front Biosci 12

      Pages: 4800-48009

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases.2007

    • Author(s)
      Kanaji, S., Tanaka, Y., Sakata, Y., Takeshita, K., Arima, K., Ohta, S., Hansell, E.J., Caffrey, C., Mottram, J.C., Lowther, J., Donnelly, S., Stack, C., Kadowaki, T., Yamamoto, K., McKerrow, J.H., Dalton, J.P., Coombs, G.H., Izuhara, K.
    • Journal Title

      FEBS Lett. 581

      Pages: 4260-4264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Selection-by-function:efficient enrichment of cathepsin E inhibitors from a DNA library2007

    • Author(s)
      Naimuddin M, Kitamura K, Kinoshita Y, Honda-Takahashi Y, Murakami M, Ito M, Yamamoto K, Hanada K, Husimi Y, Nishigaki K.
    • Journal Title

      J Mol Recognit. 20

      Pages: 58-68

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases2007

    • Author(s)
      Kanaji S, Tanaka Y, Sakata Y, Takeshita K, Arima K, Ohta S, Hansell EJ, Caffrey C, Mottram JC, Lowther J, Donnelly S, Stack C, Kadowaki T, Yamamoto K, McKerrow JH, Dalton JP, Coombs GH, Izuhara K.
    • Journal Title

      FEBS Lett. 581

      Pages: 4260-4264

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses2007

    • Author(s)
      Shin, M, Kadowaki, T, Iwata, J, Kawakubo, T, Yamaguchi, N, Takii, R, Tsukuba, T, Yamamoto, K
    • Journal Title

      Biol Chem 388

      Pages: 1173-1181

    • NAID

      120006900037

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Selection-by-function: effifient enrichment of cathepsin E inhibitors from a DNA library.2007

    • Author(s)
      Naimuddin, M., Kitamura, K., Kinoshita, Y., Honda-Takehashi, Y., Murakami, M., Ito, M., Yamamoto, K., Hanada, K., Husimi, Y., Nishigaki, K.
    • Journal Title

      J. Mol. Recognit. 20

      Pages: 58-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] The Role for Gingipains in Porphyromonas gingivalis Traffic to Phagolysosomes and Survival in Human Aortic Endothelial Cells2007

    • Author(s)
      Yamatake K, Maeda M, Kadowaki T, Takii R, Tsukuba T, Ueno T, Kominami E, Yokota S, Yamamoto K
    • Journal Title

      Infect. Immun 75

      Pages: 2090-2100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592148
  • [Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E.2007

    • Author(s)
      Kakehashi H., Nishioku T., Tsukuba T., Kadowaki T., Nakamura S., Yamamoto K.
    • Journal Title

      J. Immunol. 179

      Pages: 5728-5737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E2007

    • Author(s)
      Kakehashi H, Nishioku T, Tsukuba T, Kadowaki T, Nakamura S, Yamamoto K.
    • Journal Title

      J. Immunol 179

      Pages: 5728-5737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592148
  • [Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an inter-domain regional peptide2007

    • Author(s)
      Sakai E, Naito M, Sato K, Hotokezaka H, Kadowaki T, Kamaguchi A, Yamamoto K, Okamoto K, Nakayama K.
    • Journal Title

      J Bacteriol 189

      Pages: 3977-3986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592148
  • [Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder in macrophages showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH. *Both authors contributed equally to this work2007

    • Author(s)
      Yanagawa, M*, Tsukuba, T*, Nishioku, T, Okamoto, Y, Okamoto, K, Takii, R, Terada, Y, Nakayama, KI, Kadowaki, T, Yamamoto, K
    • Journal Title

      J. Biol Chem 282

      Pages: 1851-1862

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingivalis-infected cells2007

    • Author(s)
      Kadowaki T, Takii R, Yamatake K, Kawakubo T, Tsukuba T, Yamamoto K
    • Journal Title

      Front Biosci 12

      Pages: 4800-4809

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] The role for Gingipains in Porphyromonas gingivalis traffic to phagolysosomes and survival in human aortic endothelial cells2007

    • Author(s)
      Yamatake, K, Maeda, M, Kadowaki, T, Takii, R, Tsukuba, T, Ueno, T, Kominami, E, Yokota, S, Yamamoto, K
    • Journal Title

      Infect Immun 75

      Pages: 2090-2100

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E2007

    • Author(s)
      Kakehashi, H, Nishioku, T, Tsukuba, T, Kadowaki, T, Nakamura, S, Yamamoto, K
    • Journal Title

      J Immunol 179

      Pages: 5728-5737

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingicalis-infected cells.2007

    • Author(s)
      Kadowaki, T., Takii, R., Yamatake, K., Kawakubo, T., Tsukuba, T., Yamamoto, K.
    • Journal Title

      Frontiers in Biosci. 12

      Pages: 4800-4809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface2007

    • Author(s)
      Kawakubo T, Okamoto K, Iwata J, Shin M, Okamoto Y, Yasukochi A, Nakayama KI, Kadowaki T, Tsukuba T, Yamamoto K.
    • Journal Title

      Cancer Res. 67

      Pages: 10869-10878

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface2007

    • Author(s)
      Kawakubo, T, Okamoto, K, Iwata, J, Shin, M, Okamoto, Y, Yasukochi, A, Nakayama, KI, Kadowaki, T, Tsukuba, T, Yamamoto, K
    • Journal Title

      Cancer Res 67

      Pages: 10869-10878

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses2007

    • Author(s)
      Shin M, Kadowaki T, Iwata J, Kawakubo T, Yamaguchi N, Takii R, Tsukuba T, Yamamoto K.
    • Journal Title

      Biol Chem. 388

      Pages: 1173-1181

    • NAID

      120006900037

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder 5 showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH in macrophages.2007

    • Author(s)
      Yanagawa, M., Tsukuba, T., Nishioku, T., Okamoto, Y., Okamoto, K., Takii, R., Terada, Y., Nakayama, K.T., Kadowaki, T., Yamamoto, K
    • Journal Title

      J. Biol. Chem. 282

      Pages: 1851-1862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis,identification of its target protein on erythrocytes,and inhibition of hemagglutination by an interdomain regional peptide2007

    • Author(s)
      Sakai E, Naito M, Sato K, Hotokezaka H, Kadowaki T, Kamaguchi A, Yamamoto K, Okamoto K, Nakayama K.
    • Journal Title

      J Bacteriol. 189

      Pages: 3977-3986

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses.2007

    • Author(s)
      Shin, M., Kadowaki, T., Iwata, J., Kawakubo, T., Yamaguchi, N., Takii, R., Tsukuba, T., Yamamoto, K.
    • Journal Title

      Biol. Chem. 388

      Pages: 1173-1181

    • NAID

      120006900037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Journal Article] Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure2006

    • Author(s)
      Hashimoto, M, Kadowaki, T, Tsukuba, T, Yamamoto, K
    • Journal Title

      J. Biochein 140

      Pages: 713-723

    • NAID

      10018841154

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Novel non-uniform distribution of serotonin transporter in the mouse hippocampus and neocortex revealed by N-and C-terminal domain-specific immunohistochemistry2006

    • Author(s)
      Shigematsu N, Yamamoto K, Higuchi S, Fukuda T.
    • Journal Title

      Brain Res. 1075

      Pages: 110-116

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure2006

    • Author(s)
      Hashimoto M, Kadowaki T, Tsukuba T., Yamamoto K.
    • Journal Title

      J.Biochem. 140

      Pages: 713-723

    • NAID

      10018841154

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase2006

    • Author(s)
      Naito, M, Sakai, E, Shi, Y, Ideguchi, H, Shoji, M, Ohara, N, Yamamoto, K, Nakayama, K
    • Journal Title

      Mol Microbiol 59

      Pages: 152-67

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Gingipains inactivate a cell surface ligand on Porphyromonas gingivalis that induces TLR2-and TLR4-independent signaling2006

    • Author(s)
      Kishimoto, M, Yoshimura, A, Naito, M, Okamoto, K, Yamamoto, K, Golenbock, DT, Hara, Y, Nakayama, K
    • Journal Title

      Microbiol Immunol 50

      Pages: 315-325

    • NAID

      10018119237

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Gingipains inactivate a cell surface ligand on Porphyromonas gingival is that induces TLR2-and TLR4-independent signaling2006

    • Author(s)
      Kishimoto M, Yoshimura A, Naito M, Okamoto K, Yamamoto K, Golenbock DT, Hara Y, Nakayama K.
    • Journal Title

      Microbiol Immunol. 50

      Pages: 315-325

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Up-regulation, and enhanced maturation and secretion of cathepsin E in mouse macrophages treated with interferon-γ or lipopolysaccharide2006

    • Author(s)
      Yanagawa, M, Tsukuba, T, Okamoto, K, Terada, Y, Kadowaki, T, Yamamoto, K
    • Journal Title

      J. Oral Biosci 48

      Pages: 218-225

    • NAID

      10018041983

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors2006

    • Author(s)
      Tsukuba, T, Yamamoto, S, Yanagawa, M, Okamoto, K, Okamoto, K, Nakayama, KI, Kadowaki, T, Yamamoto, K
    • Journal Title

      J. Biochem 140

      Pages: 57-66

    • NAID

      10018843713

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors2006

    • Author(s)
      Tsukuba T., Yamamoto S., Yanagawa M., Okamoto K, Okamoto K., Nakayama KI, Kadowaki T, Yamamoto K.
    • Journal Title

      J.Biochem. 140

      Pages: 57-66

    • NAID

      10018843713

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder in macrophages showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH2006

    • Author(s)
      Yanagawa M^*., Tsukuba T^*., Nishioku T, Okamoto Y. Okamoto K., Takii R., Terada Y, Nakayama KI., Kadowaki T, Yamamoto K.
    • Journal Title

      J.Biol Chem. 282

      Pages: 1851-1862

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase2006

    • Author(s)
      Naito M, Sakai E, Shi Y, Ideguchi H, Shoji M, Ohara N, Yamamoto K, Nakayama K.
    • Journal Title

      Mel Microbiol. 59

      Pages: 152-67

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycoSylation expressed in human embryonic kidney 293T cells2006

    • Author(s)
      Tsukuba, T, Ikeda, S, Okamoto, K, Yasuda, Y, Sakai, E, Kadowaki, T, Sakai, H, Yamamoto, K
    • Journal Title

      FEBS J 273

      Pages: 219-229

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors.2006

    • Author(s)
      Tsukuba T., Yamamoto S., et al.
    • Journal Title

      J. Biochem. 140巻

      Pages: 57-66

    • NAID

      10018843713

    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Up-regulation,and enhanced maturation and secretion of cathepsin E in mouse macrophages treated with interferon-y or lipopolysaccharide2006

    • Author(s)
      Yanagawa M., Tsukuba T, Okamoto K., Terada Y, Kadowaki T, Yamamoto K
    • Journal Title

      J.Oral Biosci. 48

      Pages: 218-225

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation expressed in human embryonic kidney 293T cells2006

    • Author(s)
      Tsukuba T., Ikeda S., Okamoto K. Yasuda Y, Sakai E, Kadowaki T., Sakai H., Yamamoto K.
    • Journal Title

      FEBS J. 273

      Pages: 219-229

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Novel non-uniform distribution of serotonin transporter in the mouse hippocampus and neocortex revealed by N- and C-terminal domain-specific immunohistochemistry2006

    • Author(s)
      Shigematsu, N, Yamamoto, K, Higuchi, S, Fukuda, T
    • Journal Title

      Brain Res 1075

      Pages: 110-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Journal Article] Inhibition of Angiogenesis, Tumor Growth, and metastasis by Cathepsin E2004

    • Author(s)
      K.Yamamoto
    • Journal Title

      Exp.Med. 22

      Pages: 213-219

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209062
  • [Journal Article] Inhibition of Angiogenesis, Tumor Growth, and metastasis by Cathepsin E2004

    • Author(s)
      Yamamoto, K.
    • Journal Title

      Exp.Med.

      Pages: 213-219

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Journal Article] Periodontal Diseases and Pathogenic Proteinases2003

    • Author(s)
      Yamamoto, K.
    • Journal Title

      J.Med.Technol.

      Pages: 849-858

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Journal Article] Protease Diseases : Molecular Basis and Therapeutic Strategies2003

    • Author(s)
      Yamamoto, K.
    • Journal Title

      Folia Pharmacol.Jpn. 122

      Pages: 3-4

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Journal Article] Protease Diseases : Molecular Basis and Therapeutic Strategies2003

    • Author(s)
      K.Yamamoto
    • Journal Title

      Folia Pharmacol.Jpn. 122

      Pages: 3-4

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209062
  • [Journal Article] プロテアーゼ疾患の分子病態と治療戦略2003

    • Author(s)
      山本健二
    • Journal Title

      日本薬理学会誌 122

      Pages: 3-4

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Journal Article] Periodontal Diseases and Pathogenic Proteinases2003

    • Author(s)
      K.Yamamoto
    • Journal Title

      J.Med.Technol. 47

      Pages: 849-858

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209062
  • [Journal Article] Two Virulent Proteinases Involved in Periodontal Disease Progression.2002

    • Author(s)
      Yamamoto, K.
    • Journal Title

      KASEAA

      Pages: 72-74

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Journal Article] New Functional Aspects of Aspartic Proteinases.2001

    • Author(s)
      Yamamoto, K.
    • Journal Title

      J.Clin.Exp.Med.

      Pages: 23-28

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Journal Article] Pathophysiological Roles of Two Types of Gingipains in Periodontal Diseases.2001

    • Author(s)
      Yamamoto, K.
    • Journal Title

      Protein, Nucleic Acid and Enzyme

      Pages: 1781-1788

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Journal Article] Periodontopathogenic Proteinases.2001

    • Author(s)
      Yamamoto, K.
    • Journal Title

      Enigma of Proteolysis

      Pages: 132-142

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357016
  • [Patent] カテプシン E の腫瘍マーカーとしての用途およびカテプシン E ならびにカテプシン D の腫瘍血管新生阻害療法としての用途2010

    • Inventor(s)
      山本健二、岩田淳一
    • Industrial Property Rights Holder
      山本健二、岩田淳一
    • Acquisition Date
      2010-02-12
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Patent] カテプシンEの腫瘍マーカーとしての用途及びカテプシンEならびにカテプシンDの腫瘍血管新生阻害療法のターゲットとしての用途2010

    • Inventor(s)
      山本健二、岩田淳一
    • Industrial Property Rights Holder
      山本健二、岩田淳一
    • Filing Date
      2010-02-12
    • Acquisition Date
      2010-02-12
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Patent] 新規ペプチド及びその使用2010

    • Inventor(s)
      西垣功一、北村幸一郎、Madhu Biyani、二上雅恵、山本健二、川久保友世、安河内篤
    • Industrial Property Rights Holder
      西垣功一、北村幸一郎、Madhu Biyani、二上雅恵、山本健二、川久保友世、安河内篤
    • Industrial Property Number
      2009-245763
    • Filing Date
      2010-03-17
    • Acquisition Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Patent] アンチエイジング剤2009

    • Inventor(s)
      山本健二、川久保友世、安河内篤
    • Industrial Property Rights Holder
      山本健二、川久保友世、安河内篤
    • Industrial Property Number
      2009-264894
    • Filing Date
      2009-11-20
    • Acquisition Date
      2009-11-20
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Patent] 新規な抗癌カテプシン製剤およびそれを用いた癌併用療法抗癌剤2007

    • Inventor(s)
      山本健二、川久保友世、安河内篤
    • Industrial Property Rights Holder
      山本健二、川久保友世、安河内篤
    • Industrial Property Number
      2008-500586
    • Filing Date
      2007-02-19
    • Acquisition Date
      2007-02-19
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Presentation] Idetification of two transcripts and in vivo promoter analysis for cathepsin E2012

    • Author(s)
      Okamoto K, Sakai E, Nishishita K, Yamamoto K, Tsukuba T.
    • Organizer
      The 85^<th> Annual Meeting of Pharmacological Society
    • Place of Presentation
      京都
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Cathepsin E-induced growth arrest and apoptosis of cancer cells and the related signaling2012

    • Author(s)
      Yamamoto K, Kawakubo T, Yasukochi A, Tsukuba T.
    • Organizer
      The 85^<th> Annual Meeting of Pharmacological Society
    • Place of Presentation
      Kyoto
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Selection-by-Function 法によるプロテアーゼアクチベーターの開発2012

    • Author(s)
      小松将之、北村幸一郎、Sunita Gautam, Madhu Biyani, 山本健二、西垣功一
    • Organizer
      第17回日本病態プロテアーゼ学会
    • Place of Presentation
      浜松
    • Year and Date
      2012-08-10
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Idetification of two transcripts and in vivo promoter analysis for cathepsin E2012

    • Author(s)
      Okamoto K, Sakai E, Nishishita K, Yamamoto K, Tsukuba T
    • Organizer
      The 85^<th>Annual Meeting of Pharmacological Society
    • Place of Presentation
      Kyoto
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Accumulation of NADPH oxidase (NOX2) and increased oxidative stress in cathepsin E-deficient macrophages2012

    • Author(s)
      Tsukuba T, Kadowaki T, Okamoto K, Yamamoto K
    • Organizer
      The 85^<th>Annual Meeting of Pharmacological Society
    • Place of Presentation
      Kyoto
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Cathepsin E-induced growth arrest and apoptosis of cancer cells and the related signaling2012

    • Author(s)
      Yamamoto K., Kawakubo T., Yasukochi A. Tsukuba T
    • Organizer
      The 85^<th> Annual Meeting of Pharmacological Society
    • Place of Presentation
      京都
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Accumulation of NADPH oxidase (N0X2) and increased oxidative stress in cathepsin E-deficient macrophages2012

    • Author(s)
      Tsukuba T., Kadowaki T., Okamoto K., Yamamoto K.
    • Organizer
      The 85^<th> Annual Meeting of Pharmacological Society
    • Place of Presentation
      京都
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] カテプシンEによるガン細胞の増殖抑制とアポトーシス誘導および関連シグナリング2012

    • Author(s)
      山本健二、川久保友世、安河内篤、筑波隆幸
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Cathepsin E: related signaling systems, functions and implication in diseases2012

    • Author(s)
      Yamamoto K, Kawakubo T, Yasukochi A, Okamoto K, Tsukuba T
    • Organizer
      13th International Symposium on Proteinase Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenia
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] カテプシンE遺伝子の発現機構の解析2012

    • Author(s)
      岡元邦彰、岡本美子、坂井詠子、西下一久、山本健二、筑波隆幸
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] 反復流産病態における妊娠初期脱落膜中マクロファージの cathepsin E の役割2012

    • Author(s)
      後藤志信、尾崎康彦、都筑佳苗、安河内篤、川久保友世、国松己歳、山本健二、杉浦真弓
    • Organizer
      第17回日本病態プロテアーゼ学会
    • Place of Presentation
      浜松
    • Year and Date
      2012-08-10
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Selection-by-Function法によるプロテアーゼアクチベーターの開発2012

    • Author(s)
      小松将之、北村幸一郎、Sunita Gautam, Madhu Biyani, 山本健二、西垣功一
    • Organizer
      第17回日本病態プロテアーゼ学会
    • Place of Presentation
      浜松
    • Year and Date
      2012-08-10
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] 反復流産病態における妊娠初期脱落膜中マクロファージのcathepsin Eの役割2012

    • Author(s)
      後藤志信、尾崎康彦、都筑佳苗、安河内篤、川久保友世、国松己歳、山本健二、杉浦真弓
    • Organizer
      第17回日本病態プロテアーゼ学会
    • Place of Presentation
      浜松
    • Year and Date
      2012-08-10
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Cathepsin E : related signaling systems, functions and implication in diseases2012

    • Author(s)
      Yamamoto K., Kawakubo T., Yasukochi A., Okamoto K., Tsukuba T
    • Organizer
      13th International Symposium on Proteinase Inhibitors and Biological Control
    • Place of Presentation
      スロベニア
    • Year and Date
      2012-09-24
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] p53 はカテプシン E 遺伝子の発現を制御する2012

    • Author(s)
      岡元邦彰、岩田淳一、坂井詠子、西下一久、山本健二、筑波隆幸
    • Organizer
      第85回日本生化学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] p53はカテプシンE遺伝子の発現を制御する2012

    • Author(s)
      岡元邦彰、岩田淳一、坂井詠子、西下一久、山本健二、筑波隆幸
    • Organizer
      第85回日本生化学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] カテプシンE欠損マクロファージにおけるNADPH oxidase (NOX2)の蓄積と酸化ストレスの増加2012

    • Author(s)
      筑波隆幸、門脇知子、岡元邦彰、山本健二
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] カテプシンE結合ペプチド群を例としたP2p (Protei-topeptide)研究展開-「副作用のない創薬」を目指して-2011

    • Author(s)
      北村幸一郎、Biyani Madhu、二上雅恵、相田拓洋、後藤仁志、小松将之、川久保友世、鈴木美穂、山本健二、西垣功一
    • Organizer
      第16回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2011-08-26
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] マウス皮膚表皮細胞における内在性カテプシンEの役割2011

    • Author(s)
      安河内篤、川久保友世、中村誠司、山本健二
    • Organizer
      第16回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2011-08-26
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] DMBA/TPA二段階乳頭腫形成モデルにおける表皮カテプシンEの役割2011

    • Author(s)
      安河内篤、川久保友世、中村誠司、山本健二
    • Organizer
      第65回日本口腔科学会学術集会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2011-04-21
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] DMBA/TPA二段階乳頭腫形成モデルにおける表皮カテプシンEの役割2011

    • Author(s)
      安河内篤、川久保友世、中村誠司、山本健二
    • Organizer
      第65回日本口腔科学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Role of cathepsin E in deciduas of patients with recurrent miscarriage2011

    • Author(s)
      Goto S, Ozaki Y, Kitaori T, Yasukochi A, Kawakubo T, Sugiura M, Yamamoto K
    • Organizer
      7^<th> General Meeting of the International Proteolysis Society
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] 反復流産病態における妊娠初期頸管粘液中Cathepsin Eの役割2011

    • Author(s)
      後藤志信、尾崎康彦、大林勇輝、北折珠央、平光由衣乃、安河内篤、川久保友世、山本健二、杉浦真弓
    • Organizer
      第16回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2011-08-26
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Cathepsin E is essential for proper mammogenesis2010

    • Author(s)
      Kawakubo T, Yasukochi A, Yamamoto K
    • Organizer
      12^<th> Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz (Slovenia)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Novel functions of cathepsin E in epidermal differentiation and aging2010

    • Author(s)
      Kawakubo T, Yasukochi A, Yamamoto K
    • Organizer
      12^<th> Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz (Slovenia)
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Analysis of cathepsin E function in epidermal differentiation using a model of DMBA/TPA- induced skin papillomas2010

    • Author(s)
      Yasukochi A, Kawakubo T, Yamamoto K
    • Organizer
      12th Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz (Slovenia)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Novel functions of cathepsin E in epidermal differentiation and aging2010

    • Author(s)
      Yamamoto K
    • Organizer
      12th International Symposium on Proteinase Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenis
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Transcription factor Spl regulates the expression of the murine cathepsin E in gastric adenosarcoma cells2010

    • Author(s)
      Okamoto K, Okamoto Y, Kawakubo T, Yamamoto K, Tsukuba T
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2010-03-18
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Cathepsin E: related signaling systems, functions and implication in diseases2010

    • Author(s)
      Yamamoto K, Kawakubo T, Yasukochi A, Okamoto K, Tsukuba T
    • Organizer
      13th International Symposium on Proteinase Inhibitors and Biological Control
    • Place of Presentation
      Portoroz, Slovenis
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Cathepsin E is essential for proper mammogenesis2010

    • Author(s)
      Kawakubo T, Yasukochi A, Yamamoto K
    • Organizer
      12th Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz (Slovenia)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] Analysis of cathepsin E function in epidermal differentiation using a model of DMBA/TPA-induced skin papillomas2010

    • Author(s)
      Yasukochi A, Kawakubo T, Yamamoto K.
    • Organizer
      12^<th> Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      Portoroz (Slovenia)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-22390350
  • [Presentation] カテプシンEの機能と疾患および治療を目指して2008

    • Author(s)
      山本健二
    • Organizer
      日本病態プロテアーゼ学会
    • Place of Presentation
      大阪
    • Year and Date
      2008-08-23
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Presentation] Cathepsin E in tumor progression and bacterial infection2008

    • Author(s)
      Yamamoto K, et al.
    • Organizer
      11^<th> International Symposium on Proteinase Inhibitors and Biological Control
    • Place of Presentation
      Slovenia
    • Year and Date
      2008-08-31
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Presentation] Roles for gingipains in atherosclerosis progression accelerated by bacterial exposure2007

    • Author(s)
      Kadowaki T, Takii R, Hashimoto M, Yamatake K, Tsukuba T, Yamamoto K
    • Organizer
      5TH General Meeting of the International Proteolysis Society
    • Place of Presentation
      Patras,Greece
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] 「研究成果報告書概要(欧文)」より2007

    • Author(s)
      Yamamoto, K, Tsukuba, T, Yanagawa, M, kakehashi, H, Kawakubo, T, Kadowaki, T
    • Organizer
      10th International Symposium on Protease Inhibitor and Biological Control
    • Place of Presentation
      Portoroz, Slovenia
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] P.gingivalis感染とインスリン抵抗性に関する実験的解析2007

    • Author(s)
      門脇 知子, 瀧井 良祐, 筑波 隆幸, 岡元 邦彰, 山本 健二
    • Organizer
      第49回歯科基礎医学会学術大会
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Roles for gingipains in atherosclerosis progression accelerated by bacterial exposure2007

    • Author(s)
      Kadowaki, T, Takii, R, Hashimoto, M, Yamatake, K, Tsukuba, T, Yamamoto, K
    • Organizer
      5TH General Meeting of the International Proteolysis Society
    • Place of Presentation
      Greece
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] The role of cathepsin E in immune responses mediated by macrop hages2007

    • Author(s)
      Yamamoto K.
    • Organizer
      Special lecture for Windeyer Institute of Medical Sciences
    • Place of Presentation
      Devision of Infection & Immunity,University College of London
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] ASSOCIATION OF CATHEPSIN E WITH HOST DEFFENCE AGAINST TUMOR CELLS.(Symposium2007

    • Author(s)
      Kawakubo, T, Yasukochi, A, Okamoto, K, Y, Okamoto, Y, Kadowaki, T, Tsukuba, T, Yamamoto, K
    • Organizer
      5TH General Meeting of the International Proteolysis Society
    • Place of Presentation
      Greece
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] ASSOCIATION OF CATHEPSIN E WITH HOST DEFFENCE A GAINST TUMOR CELLS,(Symposium)2007

    • Author(s)
      Kawakubo T, Yasukochi A, Okamoto K, Y Okamoto Y, Kadowaki T, Tsukuba T, Yamamoto K
    • Organizer
      5TH General Meeting of the International Proteolysis Society
    • Place of Presentation
      Patras,Greece
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Cathepsin E differentially regulates the nature and functions of macrop hages and dendritic cells2007

    • Author(s)
      山本 健二, 他
    • Organizer
      Xthe International Symposium on Protsinase Inhibitors and Biological Control
    • Place of Presentation
      スロベニア
    • Year and Date
      2007-07-23
    • Data Source
      KAKENHI-PROJECT-19209058
  • [Presentation] P.gingivalis感染による生活習慣病増悪に関する基礎的研究2007

    • Author(s)
      門脇 知子, 瀧井 良祐, 重松 直樹, 筑波 隆幸, 山本 健二
    • Organizer
      第2回口腔健康科学シンポジウム
    • Place of Presentation
      福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] カテプシンE欠損はマクロファージの膜蛋白質輸送異常とミトコンドリア機能異常を起こす2007

    • Author(s)
      筑波 隆幸, 柳川 三千代, 岡元 邦彰, 岡本 美子, 門脇 知子, 山本 健二
    • Organizer
      第30回日本分子生物学会/第80回日本生化学会合同大会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] カテプシンE欠損によるミトコンドリア機能異常と酸化ストレス亢進2007

    • Author(s)
      筑波 隆幸, 柳川 三千代, 岡元 邦彰, 門脇 知子, 山本 健二
    • Organizer
      第49回歯科基礎医学会学術大会
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Cathepsin E exerts tumoricidal activity through generation of soluble TRAIL from the tumor cell surface2007

    • Author(s)
      Kawakubo T, Kadowaki T, Tsukuba T, Yamamoto K
    • Organizer
      第59回日本細胞生物学会大会
    • Place of Presentation
      福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] 歯周病研究の最前線-病態解明・治療を目指して2007

    • Author(s)
      山本 健二
    • Organizer
      平成19年度福岡市歯科医師会学術講演会特別講演
    • Place of Presentation
      福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Roles of cathepsin E in immune responses mediated by macrophages and dendritic cells2007

    • Author(s)
      Yamamoto K., Tsukuba T., Yanagawa M., Kakehashi H., Kawakubo T., Kadowaki T
    • Organizer
      10th International Symposium on Protease Inhibitor and Biological Control
    • Place of Presentation
      Portoroz,Slovenia
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] CONTROL OF THE ENDOSOME/LYSOSOME SYSTEM OF MACROPHAGES BY CATHEPSIN E2007

    • Author(s)
      Tsukuba, T, Okamoto, K, Kadowaki, K, Yamamoto, K
    • Organizer
      5TH General Meeting of the International Proteolysis Society
    • Place of Presentation
      Greece
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] CONTROL OF THE ENDOSOME/LYSOSOME SYSTEM OF MACR OPHAGES BY CATHEPSIN E2007

    • Author(s)
      Tsukuba T, Okamoto K, Kadowaki K, Yamamoto K
    • Organizer
      5TH General Meeting of the International Proteolysis Society
    • Place of Presentation
      Patras,Greece
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] 赤血球におけるカテプシンEの役割2007

    • Author(s)
      岡元 邦彰, 石田 豊, 坂井 詠子, 西下 一久, 山本 健二, 筑波 隆幸
    • Organizer
      第49回歯科基礎医学会学術大会
    • Place of Presentation
      札幌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] 血管新生抑制と生体防御能増強によるカテプシンEの腫瘍抑制2007

    • Author(s)
      進 正史, 門脇 知子, 川久保 友世, 瀧井 良祐, 筑波 隆幸, 山本 健二
    • Organizer
      第60回日本薬理学会西南部会
    • Place of Presentation
      宮崎
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Cathepsin E mediates membrane trafficking in macrophages2007

    • Author(s)
      Tsukuba T, Yamamoto S, Yanagawa M, Okamoto Y, Okamoto K, Yamamoto K
    • Organizer
      第80回日本薬理学会
    • Place of Presentation
      名古屋
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] 歯周病と動脈硬化2007

    • Author(s)
      山本 健二
    • Organizer
      平成19年度博多区医師会学術講演会特別講演
    • Place of Presentation
      福岡
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Cathepsin E acts as an inhibitor of tumor cells2006

    • Author(s)
      Shin M., Kadowaki T., Kawakubo T, Tsukuba, T, Yamamoto K
    • Organizer
      The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
    • Place of Presentation
      Awaji,Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Suppression of carcinogennsis and tumor growth by cathepsin E2006

    • Author(s)
      Kawakubo, T, Okamoto, K, Okamoto, Y, Tsukuba, T, Yamamoto, K
    • Organizer
      20th IUBMB Congress of Biochemistry and Molecular Biology and FAOBMB Congress
    • Place of Presentation
      Kyoto Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Roles of cathepsin E in immune responses mediated by macrophages.(Symposium)2006

    • Author(s)
      Tsukuba, T, Yanagawa, M., Yamamoto S., Kadowaki T., Yamamoto K.
    • Organizer
      The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors, Satellite Meeting of the 20th IUBMB Congress
    • Place of Presentation
      Awaji,Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Suppression of carcinogenesis and tumor growth by cathepsin E2006

    • Author(s)
      Kawakubo T, Okamoto K., Okamoto Y., Tsukuba, T, Yamamoto K
    • Organizer
      the 20th IUBMB Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congres
    • Place of Presentation
      Kyoto Japan.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] A possible mechanism for cathepsin-E mediated tumor suppression2006

    • Author(s)
      Kawakubo T, Okamoto K., Okamoto Y., Tsukuba, T, Yamamoto K
    • Organizer
      The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
    • Place of Presentation
      Awaji,Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] A possible mechanism for cathepsin-E mediated tumor suppression2006

    • Author(s)
      Kawakubo, T, Okamoto, K, Okamoto, Y, Tsukuba, T, Yamamoto, K
    • Organizer
      The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
    • Place of Presentation
      Awaii, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] カテプシンE欠損マクロファージにおける膜タンパク質の輸送異常2006

    • Author(s)
      筑波 隆幸、山本 晋也、柳川 三千代、岡元 邦彰、門脇 知子、山本 健二
    • Organizer
      第48回歯科基礎医学会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Porphyromonas gingivalisの生活習慣病増悪機構について2006

    • Author(s)
      門脇 知子、筑波 隆幸、瀧井 良佑、重松 直樹、岡元 邦彰、山本 健二
    • Organizer
      第48回歯科基礎医学会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Roles of cathepsin E in immune responses mediated by macrophages.(Symnosium)2006

    • Author(s)
      Tsukuba, T, Yanagawa, M, Yamamoto, S, Kadowaki, T, Yamamoto, K
    • Organizer
      The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors, Satellite Meeting of the 20th IUBMB Congress
    • Place of Presentation
      Awaji, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] Cathepsin E acts as an inhibitor of tumor cells2006

    • Author(s)
      Shin, M, Kadowaki, T, Kawakubo, T, Tsukuba, T, Yamamoto, K
    • Organizer
      The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
    • Place of Presentation
      Awaji, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • [Presentation] カテプシンEの過剰発現による腫瘍抑制効果2006

    • Author(s)
      進 正史、門脇 知子、川久保 友世、筑波 隆幸、山本 健二
    • Organizer
      第59回日本薬理学会西南部会
    • Place of Presentation
      那覇
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592038
  • 1.  NAKANISHI Hiroshi (20155774)
    # of Collaborated Projects: 19 results
    # of Collaborated Products: 0 results
  • 2.  TSUKUBA Takayuki (30264055)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 70 results
  • 3.  KADOWAKI Tomoko (70336080)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 77 results
  • 4.  坂井 英昭 (40225769)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  KAWAKUBO Tomoyo (70507813)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 41 results
  • 6.  KATO Yuzo (20014128)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  AKAMINE Akifumi (00117053)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  OKAMOTO Kuniaki (10311846)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 9.  TAKII Ryosuke (00419558)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 10.  HORI Nobuaki (60037520)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  YAMAMOTO Miho (50191341)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  KAMATA Osamu (80037580)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  UENO Eiko (10176612)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  YAMAATAAKE Kumiko (50622114)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  AOKI Yosuke (80049030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  IKAI Atsushi (50011713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KATO Ihachi (30005087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  EZAKI Mitsue (30223647)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KUNIMATSU Kazushi (20170011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKAYAMA Koji (80150473)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  NAKAYAMA Hiroaki (70047744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  朔 敬 (40145264)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  後藤 康治 (00170473)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  金井 貞
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  浅尾 哲次
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  TETSUJI Asao
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  浅尾 哲治
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  SHIN Masashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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