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Ishibashi Michio
石橋 道男
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Alternative Names
ISHIBASHI Michio 石橋 道男
ISHIBASHI Michiko 石橋 道男
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Researcher Number
40107032
Affiliation (Current)
2020: 奈良県立医科大学, 医学部, 研究員
Affiliation (based on the past Project Information)
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2016 – 2018: 奈良県立医科大学, 医学部, 研究員
2011 – 2014: 奈良県立医科大学, 医学部, 研究員
2007 – 2011: Nara Medical University, 医学部, 講師
2001 – 2002: 奈良県立医科大学, 医学部, 講師
1991: Osaka Univ Depat of Urology Assoc Prof., 医学部, 助教授
1989 – 1990: 大阪大学, 医学部, 講師
1986: Osaka University Hospital, Department of Urology,Associate Prof., 医学部, 講師
Review Section/Research Field
Principal Investigator
Urology
/
Urology
Except Principal Investigator
Urology
Keywords
Principal Investigator
マクロファージ / ベンゾイソフラノン化合物 / ガンマラクトン化合物 / 多発性嚢胞腎 / ＰＣＫラット / ベンゾイソフラノン誘導体 / 腎障害修復と再生 / heterodimeric aminoacid transporter / 4F2hc(CD98) / rBAT
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/ 腎急性糸球体障害 / 腎閉塞性尿細管障害 / 腎修復と再生 / 4F2hc(CD98)-LAT2 / Asc1 / Asc2 / 腎糸球体病変 / 一側腎尿管閉塞解除ラットモデル / ガンマラクトン低分子化合物 / ベンゾイソフラノン低分子化合物 / TNF-α / アポトーシス / ガレクチン-3 / マトリックス応答 / 血管新生 / 1型コラーゲン / CD98/4F2hc/rBAT / リコンビナントTNF-alpha / 抗アポトーシス活性 / 急性腎障害修復と再生 / rBAT heavy chain of heterodimeric aminoacid transpoter / 一側尿管閉塞・解除腎モデル / rBAT heavy chain of heterodimeric aminoacid transporter / 細胞マトリックス / ラットＰＣＫ / 細胞外マトリクス / ＤＮＡメチル化 / 慢性拒絶反応 / 慢性移植腎機能障害 / 尿管閉塞・解除による腎障害 / CD11b / ケモカインレセプター / 腎移植 / 尿管閉塞腎 / 接着分子 / Macrophage / CD11b of β2-integrin / chronic allograft rejection / unilateral ureteral obstruction / chemokine receptor / polycystic kidney / pericyte / 内在性レトロウイルス / Gag遺伝子 / HIF / PCKラット / ペリサイト / NG2 / HIF-1 / CD31 / 血管保護
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Except Principal Investigator
拒絶反応 / OKT4 / OKT8 / 同種拒絶反応 / 活性化単球 / 補体レセプタ-3 / 接着分子 / 溶血 / 皮膚移植 / complement receptor 3 / 活性化マクロファ-ジ / サイクロスポリン / Allograft rejection / Activated monocytes / Complement receptor 3 / Adhesion molecules / Hemolysis / リンパ球混合反応 / 細胞障害性試験 / デオキシスパガリン / デオキシメチルスパガリン / 免疫抑制剤 / 臓器移植 / メチルデオキシスパガリン / Mixed Lymphocyte Reaction / Cell Mediated Lympholysis / Deoxyspergualin / Deoxymethylspergualin / Immunosuppressive Agent / Organ Transplantation / リンパ球サブセット / 感染症 / サイトメガロウイルス / T8ーFITC / S6FーRD1 / リンパ球 / subset / rejection / infection / cytomegarovirus / T8-FITC / S6F-RD1 / 腎移植 / 単球 / インフルエンザウイルス / Renal Transplantation / Monocytes / Rejection
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Research Projects
(
9
results)
Research Products
(
9
results)
Co-Researchers
(
10
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Ameriolation of progression of polycystic kidney disease by stabilization of renal vessel disorders and exploration of endogenous retrovirus responses in macrophages
Principal Investigator
Principal Investigator
Ishibashi Michio
Project Period (FY)
2016 – 2018
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Urology
Research Institution
Nara Medical University
Basic studies of therapeutic modality for polycystic kidney disease explored by epigenetic modification of cellular matrix-adhesion proteins
Principal Investigator
Principal Investigator
ISHIBASHI MIchio
Project Period (FY)
2012 – 2014
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Urology
Research Institution
Nara Medical University
Study of proper mechanism of repair and regeneration after kidney injury evoked by novel gammalactone low molecular compounds derivatives with cytokines
Principal Investigator
Principal Investigator
ISHIBASHI Michio
Project Period (FY)
2009 – 2011
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Urology
Research Institution
Nara Medical University
Investigation on the mechanism of kidney repair and regeneration against the process of progressive renal diseases explored by gammalactone compounds
Principal Investigator
Principal Investigator
ISHIBASHI Michio
Project Period (FY)
2007 – 2008
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Urology
Research Institution
Nara Medical University
Study on the Rationale of Prevention of chronic allograft rejection explored by Inhibitory compound of macrophage-effector generation
Principal Investigator
Principal Investigator
ISHIBASHI Michio
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Urology
Research Institution
Nara Medical University
Flow cytometry analysis of rejection and infection with monoclonal antibody in renal transplant recipients
Principal Investigator
KOKADO Yukito
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Urology
Research Institution
Osaka University
Comparative Study of Allograft Rejection in Man and Rat : Analysis of Activated Monocytes Involing in Acute Rejection.
Principal Investigator
SONODA Takao
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Urology
Research Institution
Osaka University Medical School
Immunosuppressive mode of action of deoxyspergualin and deoxymethylspergualin
Principal Investigator
TAKAHARA Shiro
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Urology
Research Institution
Osaka University
Graft rejection mechanism by monocytes and specific immunosuppression.
Principal Investigator
SONODA Takao
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Urology
Research Institution
Osaka University Medical School
All
2019
2018
2011
2009
2008
2006
All
Presentation
Patent
[Patent] 新規ベンゾイソフラノン誘導体による臓器組織の修復再生治療薬
2011
Inventor(s)
石橋道男(奈良県立医科大学泌尿器科学教室)小島直人、(大阪大学大学院薬学研究科薬品製造化学分野)、田中徹明(大阪大学大学院薬学研究科薬品製造化学分野)
Industrial Property Rights Holder
公立大学法人奈良県立医科大学
Industrial Property Number
2011-035260
Filing Date
2011-02-21
Data Source
KAKENHI-PROJECT-21592083
[Patent] 腎糸球体治療剤のスクリーニング方法
2006
Inventor(s)
石橋 道男
Industrial Property Rights Holder
石橋 道男
Industrial Property Number
2006-161569
Filing Date
2006-06-09
Data Source
KAKENHI-PROJECT-19591883
[Presentation] NG2活性化による腎髄質ペリサイト機能温存とラットPCK 多発性嚢胞腎モデルにみられる糸球体病変の軽減
2019
Author(s)
熊本海生航、釘田雅則、吉村文、藤本清秀、千原良友、小島直人、東原英二、長尾静子、石橋道男
Organizer
第62回日本腎臓学会学術総会、2019年6月21日 名古屋
Data Source
KAKENHI-PROJECT-16K11058
[Presentation] 多発性嚢胞腎ラットへの低分子化合物NK0070投与によるNG2 pericyte マーカーの温存と腎病変
2018
Author(s)
石橋道男、釘田雅則、熊本海生航、吉村 文、 藤本清秀、東原英二、長尾静子
Organizer
第４８回日本腎臓学会東部学術大会、平成30年（2018）10月20日~21日、東京
Data Source
KAKENHI-PROJECT-16K11058
[Presentation] Important Repair/protective Process of Papillae in Renal Function and Morphology demonstrated by Use of 14 days-UUO-released Model and Small Synthetic Compounds in Rats
2011
Author(s)
M Ishibashi, T Nakatani, M Iwano, K Fujimoto, Y Kanai, Yoshihiko Hirao
Organizer
American Society for Nephrology(ASN) Renal week 2011
Place of Presentation
Philadelphia, U. S. A
Year and Date
2011-11-12
Data Source
KAKENHI-PROJECT-21592083
[Presentation] Important Repair/protective Process of Papillae in Renal Function and Morphology demonstrated by Use of 14 days-UUO-released Model and Small Synthetic Compounds in Rats
2011
Author(s)
Michio Ishibashi, et al
Organizer
American Society for Nephrology(ASN) Renal week 2011
Place of Presentation
Philadelphia, U.S.A.
Year and Date
2011-11-12
Data Source
KAKENHI-PROJECT-21592083
[Presentation] Potentialisation of repair of renal tubular lesions by combined use of novel gammalactone derivatives and tumor necrosis factors
2009
Author(s)
M Ishibashi, M Iwano, K Fujimoto, Y Ito, Y Hirao, Y Kanai
Organizer
Abstract of 2009 Annual Meeting of American Society of Nephrology
Place of Presentation
San Diego, USA
Data Source
KAKENHI-PROJECT-21592083
[Presentation] Action of the combination of interferon-γor TNF-β and gammalactone derivatives on expression of heavy chains (4F2hc/rBAT) of heterodimeric amino acid transporters (HAT) in macrophages and repair of renal glomerular or tubular lesions
2008
Author(s)
M Ishibashi, M Miyake, K.Saito, K Fujimoto, M Iwano, T Yamamoto, Y Ito, Y Hirao and Y Kanai
Organizer
Abstract of 2008 Annual Meeting of American Society of Nephrology
Place of Presentation
Philadelphia, USA
Data Source
KAKENHI-PROJECT-19591883
[Presentation] Action of the combination of interferon-Yor TNF-B and gammalactone derivatives on expression of heavy chains (4F2hc/rBAT) of heterodimeric amino acid transporters (HAT)in macrophages and repair of renal glomerular or tubular lesions
2008
Author(s)
M Ishibashi, M Miyake, K. Saito, K Fujimoto, M Iwano, T Yamamoto, Y Ito, Y Hirao, Y Kanai
Organizer
Abstract of 2008 Annual Meeting of American Society of Nephrology
Place of Presentation
Philadelphia, USA
Data Source
KAKENHI-PROJECT-19591883
# of Projects (Dsc)
# of Projects (Asc)
1.
FUJIMOTO Kiyohide
(50264867)
# of Collaborated Projects:
3 results
# of Collaborated Products:
4 results
2.
TAKAHARA Shiroh
(70179547)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
3.
KOKADO Yukito
(30186639)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
HIGASHIHARA Eiji
(00092312)
# of Collaborated Projects:
2 results
# of Collaborated Products:
2 results
5.
NAGAO Shizuko
(20183527)
# of Collaborated Projects:
2 results
# of Collaborated Products:
2 results
6.
SONODA Takao
(80028290)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
CHIHARA Yoshitomo
(40405395)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
KOJIMA Naoto
(90420413)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
YOSHIDA Katsunori
(50192422)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
NAKANO Etsuji
(90116070)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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