AIKAWA Naoki 相川直樹

Researcher Number	40110879
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2001 – 2007: Keio Univ., School of Medicine, Professor, 医学部, 教授 2000: 慶應義塾大学, 医学部, 助教授 1998 – 1999: 慶應義塾大学, 医学部, 教授 1988: Department of Surgery, School of Medicine, Keio University, 医学部外科, 助手 1988: 慶應義塾大学医学部, 外科, 助手 … More 1987: 慶應義塾大学, 医学部・外科, 助手 1986: Department of Surgery, School of Medicine, Keio University, 医学部, 助手 1986: School of Medicine, Keio University, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General surgery / Emergency medicine Except Principal Investigator General surgery / Public health/Health science / Anesthesiology/Resuscitation studies / Hygiene / Public health/Health science
Keywords	Principal Investigator sepsis / SIRS / 高体温 / LPS / priming / ARDS / HGF / 高濃度酸素 / hyperthermia / hypothermia … More / cytokine / 低体温 / サイトカイン / Diuresis Norepinephrine / Dopamine / Atrial Natriuretic Hormone / Surgical stress / 利尿 / ドーパミン / ノルエプネフリン / 心房性Na利尿ホルモン / 循環動態 / 外科侵襲 / TNF / protein C / 高温環境 / MDC / CCL22 / Sepsis / coagulation and fibrinolysis / hyperoxia / インターロイキン12 / MAPキナーゼ / 好中球エラスターゼ / 凝固因子 / 熱傷 / インターロイキン18 / 敗血症 / 凝固線溶系 / 熱中症 / whole blood culture / body temperature / interleukin-8 / IL-6 / TNFα / 全血培養 / IL-8 / 体温 … More Except Principal Investigator ショック / サイトカイン / 熱中症 / 高体温 / 急死 / 入浴 / EGF / アシドーシス / cytokine / hyperthermia / bathing / 循環不全 / thermal injury / bulla / EGF receptor / 創傷治癒 / Broxiuridine / 傍基底細胞 / 基底細胞 / 扁平上皮組織 / 水疱 / 増殖作用 / S期細胞 / EGF受容体 / 組織修復 / 肝灌流 / 肝切除 / Fibroblast Growth Factor / C-myc / 肝再生 / 熱傷 / 水疱液 / 増殖能 / EGFレセプター / Pharmacokinetics / Antibiotics / Surgical stress / 腎機能 / 薬動力学 / 抗生物質 / 外科的侵襲 / rat / heat stroke / shock / water immersion / 心肺停止 / hyperoxia / survival / acidosis / tissue oxygen metabolism / fluid replacement / resuscitation / experimental model / hemorrhagic shock / 臓器障害 / 酸素代謝 / トノメーター / 血栓 / 外傷 / 出血モデル / 動脈血酸素分圧 / 生存率 / 組織酸素代謝 / 輸液 / 蘇生 / 実験モデル / 出血性ショック / heart rate variability / heat illness / Sudden death / 心拍変動 Less

Immunological and metabolic changes induced by severe insults : insights into its pathophysiology and a development of new therapiesPrincipal Investigator
- Principal Investigator
  
  AIKAWA Naoki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Keio University
入浴中急死(熱中症)の防止対策:免疫修飾による治療戦略の検討
- Principal Investigator
  
  HORI Shingo
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Public health/Health science
- Research Institution
  Keio University
Sudden death during bating: cardiovascular collapse by experimental hyperthermia
- Principal Investigator
  
  HORI Shingo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Keio University
Analysis of altered immunological responses under abnormal environmental conditions, including environmental temperature, and the trial of its active modulation for the treatment of critically ill patientsPrincipal Investigator
- Principal Investigator
  
  AIKAWA Naoki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Keio University
An experimental study on hypotensive resuscitation of near-lethal uncontrolled hemorrhage : Effects on tissue dysoxia, mortality and end-organ function at 72 hours
- Principal Investigator
  
  AOKI Katsunori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hamamatsu University School of Medicine
  Keio University
Identification of cause of sudden death during hot waterbathing
- Principal Investigator
  
  HORI Shingo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Keio University
Biomedical responses to changes in body temperature in ciritically ill patientsPrincipal Investigator
- Principal Investigator
  
  AIKAWA Naoki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Keio University
Experimental Study of Cell Growth Factors on Tissue Repair
- Principal Investigator
  
  ABE Osahiko
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Keio University
Pharmacokinetic changes of antibiotics by surgical stress and their clinical role
- Principal Investigator
  
  ISHIBIKI Kyuya
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Keio University
Experimental and Clinical Study for Atrial Natriuretic Hormone and Hemodynamics on Surgical StressPrincipal Investigator
- Principal Investigator
  
  AIKAWA Naoki
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Department of Surgery, School of Medicine,Keio University

All 2008 2007 2006 2005 2004 2003 2002

All Journal Article Presentation Book Patent

[Book] 深在性真菌症の診断・治療ガイドライン20072007
- Author(s)
  相川直樹, 他
- Total Pages
  127
- Publisher
  深在性真菌症のガイドライン作成委員会
- Data Source
  KAKENHI-PROJECT-17390482
[Book] 救急救命士標準テキスト2007
- Author(s)
  相川直樹, 他
- Publisher
  へるす出版
- Data Source
  KAKENHI-PROJECT-17390482
[Book] MRSA-基礎・臨床・対策-2006
- Author(s)
  藤島清太郎, [相川直樹]他
- Total Pages
  300
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-17390482
[Book] 敗血症の解明と治療戦略2006
- Author(s)
  藤島清太郎, 相川直樹, 他
- Total Pages
  382
- Publisher
  医薬ジャーナル
- Data Source
  KAKENHI-PROJECT-17390482
[Book] 抗菌薬使用のガイドライン2005
- Author(s)
  相川直樹, 他
- Total Pages
  280
- Publisher
  日本感染症学会/日本化学療法学会
- Data Source
  KAKENHI-PROJECT-17390482
[Book] 抗菌薬使用のガイドライン2005
- Author(s)
  相川直樹, 他
- Publisher
  日本感染症学会/日本化学療法学会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390482
[Book] 臨床に生かす体液管理・輸液マニュアル2005
- Author(s)
  相川直樹[監修], 他
- Total Pages
  287
- Publisher
  照林社
- Data Source
  KAKENHI-PROJECT-17390482
[Book] 発熱性好中球減少症2005
- Author(s)
  藤島清太郎, 相川直樹, 他
- Total Pages
  146
- Publisher
  医薬ジャーナル
- Data Source
  KAKENHI-PROJECT-17390482
[Book] SIRS,ALI患者血中の凝固線溶系因子、顆粒球エラスターゼ、同分解XDP等の検討2004
- Author(s)
  藤島清太郎, 相川直樹, 他
- Publisher
  TTMフオーラム
- Data Source
  KAKENHI-PROJECT-14370364
[Book] Development and treatment of sepsis2002
- Author(s)
  Fry D, Naoki Aikawa
- Publisher
  Surgical Infections
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] 救急患者における人工呼吸器関連肺炎の臨床的検討2008
- Author(s)
  宮木大、[相川直樹]
- Journal Title
  
  日本外科感染症学会雑誌 5
  
  Pages: 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Neutrophil elastase and systemic inflammatory response syndrome in the initiation and development of acute lung injury among critically ill patients2008
- Author(s)
  S Fujishima, [N Aikawa], et. al.
- Journal Title
  
  Biomedicine & Pharmacotherapy (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Neutrophil elastase and systemic inflammatory response syndrome in the initiation and development of acute lung injury among critically ill patients2008
- Author(s)
  S, Fujishima, [N, Aikawa], et. al.
- Journal Title
  
  Biomedicine & Pharmacotherapy (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Prostaglandin E^2 induces hypertrophic changes and suppresses α-skeletal actin gene expression in rat cardiomyocytes2007
- Author(s)
  S Miyatake, [N Aikawa]
- Journal Title
  
  Journal of Cardiovascular Pharmacology 50
  
  Pages: 548-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 細菌性髄膜炎から急激にDIC, Septic shockを呈し心肺停止に至った1剖検例2007
- Author(s)
  林田敬, [相川直樹]他
- Journal Title
  
  日本集中治療医学会雑誌 14
  
  Pages: 260-260
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 輸液療法に反応した深在性複雑型肝損傷における非手術的治療の限界2007
- Author(s)
  関根和彦, [相川直樹]他
- Journal Title
  
  日本腹部救急医学会雑誌 27
  
  Pages: 155-155
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] BeadArrayシステムを用いた遺伝子発現変動の網羅的解析 : 高度侵襲下病態解析への応用2006
- Author(s)
  藤島清太郎, [相川直樹]他
- Journal Title
  
  日本救急医学会雑誌 17
  
  Pages: 344-344
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] ALI/ARDS患者の気道被覆液および血清エンドセリン-1濃度の検討2006
- Author(s)
  田坂定智, [相川直樹]他
- Journal Title
  
  日本Shock学会雑誌 21
  
  Pages: 39-39
- NAID
  10024300193
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 救急患者におけるALI/ARDS病態と好中球エラスターゼ(NE)2006
- Author(s)
  藤島清太郎, [相川直樹]他
- Journal Title
  
  日本救急医学会雑誌 17
  
  Pages: 395-395
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Sepsis救命ガイドライン重症sepsisおよびseptic shock患者に対する抗菌薬療法(エビデンスに基づくレビュー)2006
- Author(s)
  相川直樹
- Journal Title
  
  救急・集中治療別冊
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] The role of the surgeon as intensivist: an international perspective2006
- Author(s)
  Jeffrey L, [Aikawa N], et. al.
- Journal Title
  
  Current Opinion in Critical Care 12
  
  Pages: 357-369
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 外傷性脳損傷の急性期メディエーターの制御と神経再生2006
- Author(s)
  並木淳, [相川直樹]他
- Journal Title
  
  日本救急医学会雑誌 17
  
  Pages: 543-543
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation : results of a phase III, randomized, double-blind climical trial2006
- Author(s)
  Saito H, [Aikawa N], et al.
- Journal Title
  
  Journal of Thrombosis and Haemostasis 5
  
  Pages: 31-41
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 急性硬膜下血腫に対する脳圧制御目標型の手術・術後(外減圧・バルビツレート・脳平温・浸透圧利尿薬・軽度過換気による複合治療2006
- Author(s)
  並木淳, [相川直樹]他
- Journal Title
  
  日本救急医学会雑誌 17
  
  Pages: 464-464
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 耐性グラム陽性球菌治療の新しい選択肢-リネゾリドを中心に-2006
- Author(s)
  相川直樹
- Journal Title
  
  日本科学療法学会雑誌 54
  
  Pages: 17-17
- NAID
  10017426028
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] アムビゾーム; Drug delivery systemを応用して開発されたアムホテリシンBリポソーム2006
- Author(s)
  相川直樹
- Journal Title
  
  日本病院薬剤師会雑誌 43
  
  Pages: 557-560
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] ステロイド薬-感染症治療におけるステロイド薬の位置づけ-2006
- Author(s)
  佐々木淳一, [相川直樹]他
- Journal Title
  
  日本臨床 65
  
  Pages: 315-319
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 生体侵襲・生体反応と臓器不全2006
- Author(s)
  藤島清太郎, 関根和彦, 相川直樹
- Journal Title
  
  救急医学 30
  
  Pages: 1025-1031
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Pharmacokinetic-pharmacodynamic relationship of Arbekacin for treatment of patients infected with Methicillin-resistant Staphylococcus aureus2006
- Author(s)
  Sato R, [Aikawa N], et al.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 50
  
  Pages: 3763-3769
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] The role of the surgeon as intensivist : an intensivist : an international2006
- Author(s)
  Jefirey L, [Aikawa N], et al.
- Journal Title
  
  Current Opinion in Critical Care 12
  
  Pages: 357-369
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] The role of the surgeon as intensivist : an international perspective2006
- Author(s)
  Jeffrey, L, [Aikawa, N], et. al.
- Journal Title
  
  Current Opinion in Critical Care 12
  
  Pages: 357-369
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Sepsis患者における凝固線溶系動態と病態への関与2006
- Author(s)
  藤島清太郎, [相川直樹]他
- Journal Title
  
  日本臨床救急医学会雑誌 9
  
  Pages: 138-138
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] The surgeon in the intensive care unit : a Japanese perspective2006
- Author(s)
  Aikawa N
- Journal Title
  
  Current Opinion in Critical Care 12
  
  Pages: 364-365
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 重症肺炎に伴うsepsis関連病態,ALI/ARDSの治療2006
- Author(s)
  藤島清太郎, 相川直樹
- Journal Title
  
  呼吸器科 9
  
  Pages: 52-59
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Orthostatic decrease in cardiac chaos during the head-up tilt test in patients with vasovagal syoncope2006
- Author(s)
  Suzuki M, [Aikawa N], et al.
- Journal Title
  
  Circulation Journal 70
  
  Pages: 902-908
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Population pharmacokinetics of Arbekacin in patients infected with methicillin-resistant Staphylococcus aureus2006
- Author(s)
  Tanigawara Y, [Aikawa N], et al.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 50
  
  Pages: 3754-3762
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 高度侵襲下で発症したSepsisに対する早期輸液療法の生存率改善効果2006
- Author(s)
  葉季久雄, [相川直樹]他
- Journal Title
  
  日本救急医学会雑誌 17
  
  Pages: 385-385
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 基礎傷病に続発したseptic ALI/ARDSに対するsteroidの治療効果マウス熱傷後sepsisモデルによる検討2006
- Author(s)
  佐々木淳一, [相川直樹]他
- Journal Title
  
  日本外科感染症学会雑誌 3
  
  Pages: 400-400
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 重症熱傷患者における血流感染の予測因子の検討2006
- Author(s)
  葉季久雄, [相川直樹]他
- Journal Title
  
  日本外科感染症学会雑誌 3
  
  Pages: 458-458
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 抗MRSA薬の適正使用について2006
- Author(s)
  砂川慶介, [相川直樹]他
- Journal Title
  
  Japanese Journal of Antibiotics 60
  
  Pages: 1-16
- NAID
  10018550901
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] ERにおけるSepsis患者に対する抗菌薬投与開始までの時間の検討2006
- Author(s)
  林田敬, [相川直樹]他
- Journal Title
  
  日本救急医学会雑誌 17
  
  Pages: 384-384
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 肺血栓塞栓症の主訴と生命予後の検討2006
- Author(s)
  船曵知弘, [相川直樹]他
- Journal Title
  
  日本臨床救急医学会雑誌 9
  
  Pages: 156-156
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Surviving sepsis campaign guidelines に基づく治療が奏功した重症肺炎によるDIC合併感染性ショックの1例2006
- Author(s)
  林正憲, [相川直樹]他
- Journal Title
  
  日本臨床救急医学会雑誌 9
  
  Pages: 149-149
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Cost-minimisation analysis of sivelestat for acute lung injury associated with systemic inflammatory response syndrome2005
- Author(s)
  Aikawa N, Fujishima S, et al.
- Journal Title
  
  Pharmacoeconomics 23
  
  Pages: 169-181
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Voriconazoleの開発の経緯2005
- Author(s)
  相川直樹
- Journal Title
  
  日本化学療法学会雑誌 53S-2
  
  Pages: 4-7
- NAID
  10017083414
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Multicenter prospective study of procalcitonin as an indicator of sepsis.2005
- Author(s)
  Naoki Aikawa, Seitaro Fujishima
- Journal Title
  
  J Infect Chemother (in press)
- NAID
  10016473065
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Multicenter prospective study of procalcitonin as an indicator of sepsis.2005
- Author(s)
  Aikawa N, Fujishima S, et al.
- Journal Title
  
  J Infect Chemother (in press)
- NAID
  10016473065
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Multicenter prospective study of procalcitonin as an indicator of sepsis2005
- Author(s)
  Aikawa N, Fujishima S, et al.
- Journal Title
  
  J Infect Chemother 11
  
  Pages: 152-159
- NAID
  10016473065
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Heat stroke with multiple organ failure treated with cold hemodialysis and cold continuous hemo-diafiltration : a case report2005
- Author(s)
  Wakin, s, [Aikawa, N], et. al.
- Journal Title
  
  Ther Apher Dial 9
  
  Pages: 423-428
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Cost-minimisation analysis of sivelestat for acute lung injury associated with systemic inflammatory response syndrome.2005
- Author(s)
  Aikawa N, Fujishima S, Kobayashi M, Matsuoka S, Abiru T.
- Journal Title
  
  Pharmacoeconomics 23(2)
  
  Pages: 169-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Epidemiological and outcome characteristics of major burns in Tokyo2005
- Author(s)
  Kobayashi K, [Aikawa N], et al.
- Journal Title
  
  Burns 31 Suppl 1
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Current status of diagnosis and treatment of invasive fungal infections in Japan : the influence of the new Japanese guidelines2005
- Author(s)
  Aikawa N, Kohno S, et al.
- Journal Title
  
  J infect Chemother 11
  
  Pages: 278-287
- NAID
  10016911976
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Heat stroke with multiple organ failure treated with cold hemodialysis and cold continuous hemodiafiltration : a case report2005
- Author(s)
  Wakino S, [Aikawa N], et al.
- Journal Title
  
  Ther Apher Dial 9
  
  Pages: 423-428
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Cost-minimisation analysis of sivelestat for acute lung injury associated with systemic inflammatory response syndrome.2005
- Author(s)
  Aikawa N, Fujishima S, et al.
- Journal Title
  
  Pharmacoeconomics 23(2)
  
  Pages: 169-181
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Cost-minimisation analysis of sivelestat for acute lung injury associated with systemic inflammatory response syndrome2005
- Author(s)
  Aikawa N, Fujishima S, et al.
- Journal Title
  
  Pharmacoeconomics 23(2)
  
  Pages: 169-181
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Emergency medical services in Japan : an opportunity for the rational development of pre-hospital care and research2005
- Author(s)
  M.R.Lewin, [Aikawa N], et al.
- Journal Title
  
  J Emerg Med 28
  
  Pages: 237-241
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Prognostic implications of inhalation injury in burn patients in Tokyo2005
- Author(s)
  Suzuki M, Aikawa N, et al.
- Journal Title
  
  Burns 31
  
  Pages: 331-336
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] 深在性真菌症に対するvoriconazoleの臨床試験-他施設共同、非対照試験-2005
- Author(s)
  二木芳人, [相川直樹], 他
- Journal Title
  
  日本化学療法学会雑誌 353S-2
  
  Pages: 32-50
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Heat stroke with multiple organ failure treated with cold hemodialysis and cold continuous hemodiafiltration:a case report2005
- Author(s)
  Wakino S, [Aikawa N], et. al.
- Journal Title
  
  Ther Apher Dial 9
  
  Pages: 423-428
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] A case of severe heat stroke with abnormal cardiac findings2005
- Author(s)
  Wakino S, [Aikawa N], et al.
- Journal Title
  
  Int Heart J 46
  
  Pages: 543-550
- NAID
  130000068508
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Flow-independent myocardial ischemia induced by endothelin-1 : an NADH fluorescence analysis2005
- Author(s)
  Inoue S, [Aikawa N], et al.
- Journal Title
  
  J Cardiovasc Pharmacol 46
  
  Pages: 810-816
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Plasma hepatocyte growth factor is increased in early-phase sepsis.2004
- Author(s)
  Kazuhiko Sekine, Seitaro Fujishima, Naoki Aikawa
- Journal Title
  
  J Infect Chemother Vol.10
  
  Pages: 110-114
- NAID
  10016521422
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Plasma hepatocyte growth factor is increased in early-phase sepsis.2004
- Author(s)
  Sekine K, Fujishima S, Aikawa N
- Journal Title
  
  J Infect Chemother 110
  
  Pages: 110-114
- NAID
  10016521422
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Relationship between neutrophil elastase and acute lung injury in humans2004
- Author(s)
  Tamakuma S, Aikawa N, et al.
- Journal Title
  
  Pulm Pharmacol Ther 17(5)
  
  Pages: 271-279
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] CCL22 and CCL17 in rat radiation pneumonitis and in human idiopathic pulmonary fibrosis2004
- Author(s)
  Inoue T, Fujishima S, Aikawa N, et al.
- Journal Title
  
  Eur Respir J 24(1)
  
  Pages: 49-56
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Relationship between neutrophil elastase and acute lung injury in humans.2004
- Author(s)
  Shouetsu Tamakuma, Michio Ogawa, Naoki Aikawa, et al.
- Journal Title
  
  Pulmonary Pharmacology & Therapeutics Vol.17
  
  Pages: 271-279
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Plasma hepatocyte growth factor is increased in early-phase sepsis2004
- Author(s)
  Sekine K, Fujishima S, Aikawa N, et al.
- Journal Title
  
  J Infect Chemother 10(2)
  
  Pages: 110-114
- NAID
  10016521422
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] 外科的侵襲に対する生体反応:最新の知見2004
- Author(s)
  相川直樹
- Journal Title
  
  日本外科学会雑誌 104(12)
  
  Pages: 809-810
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Flow cytometric detection of cell-associated IL-8 in alveolar macrophages in vivo from patients with HP and sarcoidosis2004
- Author(s)
  Fujishima S, Aikawa N, et al.
- Journal Title
  
  Scand J Clin Lab Invest 64(3)
  
  Pages: 237-243
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] CCL22 and CCL17 in rat radiation pneumonitis and in human idiopathic pulmonary fibrosis.2004
- Author(s)
  Inoue T, Fujishima S, Aikawa N, et al.
- Journal Title
  
  Eur Respir J 24(1)
  
  Pages: 49-56
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Cytokine storm in extensive bums : mechanisms and pharmacological modulation of cytokine-induced systemic inflammation.2003
- Author(s)
  Aikawa N, Fujishima S, et al.
- Journal Title
  
  Dialysis transplantation and burn 114(1)
  
  Pages: 1-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Prior burn insult induces lethal acute lung injury in endotoxemic mice : effects of cytokine inhibition.2003
- Author(s)
  Sasaki Junichi, Fujishima Seitaro, Naoki Aikawa, et al.
- Journal Title
  
  American journal of physiology -lung cellular and molecular physiology Vol.284, No2
  
  Pages: 270-278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Prior burn insult induces lethal acute lung injury in endotoxemic mice: effects of cytokine inhibition.2003
- Author(s)
  Sasaki J, Fujishima S, Aikawa N, et al.
- Journal Title
  
  American journal of physiology -lung cellular and molecular physiology 284(2)
  
  Pages: 270-278
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Cytokine storm in extensive burns : mechanisms and pharmacological modulation of cytokine-induced systemic inflammation2003
- Author(s)
  Naoki, Aikawa, Fujishima Seitaro, Sasaki Junichi
- Journal Title
  
  Dialysis transplantation and burn Vol.14, No1
  
  Pages: 1-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Development and treatment of sepsis.2002
- Author(s)
  Fry D, Naoki Aikawa
- Journal Title
  
  Surgical Infections
  
  Pages: 48-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Total Burn Care ; Second.2002
- Author(s)
  Yohtaro Shinozawa, Naoki Aikawa
- Journal Title
  
  Edition. Renal failure in burned patients
  
  Pages: 393-398
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Use of antifungal agents in febrile patients nonresponsive to antibacterial treatment: the current status in surgical and critical care patients in Japan2002
- Author(s)
  Naoki Aikawa, Sumiyama Yoshinobu, et al.
- Journal Title
  
  Journal of infection and chemotherapy Vol.8, No2
  
  Pages: 237-241
- NAID
  10013892938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Patent] 医薬組成物及び治療方法2005
- Inventor(s)
  相川直樹, 他
- Industrial Property Rights Holder
  慶應義塾
- Acquisition Date
  2005-11-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390482
[Patent] 医薬組成物及び治療方法2005
- Inventor(s)
  相川直樹, 他
- Industrial Property Rights Holder
  慶應義塾
- Filing Date
  2005-05-17
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-17390482
[Patent] 医薬組成物及び治療方法2004
- Inventor(s)
  相川直樹, 藤島清太郎, 関根和彦
- Industrial Property Rights Holder
  慶應義塾
- Filing Date
  2004-05-21
- Data Source
  KAKENHI-PROJECT-14370364
[Patent] 医薬組成物及び治療方法2004
- Inventor(s)
  相川直樹, 藤島清太郎, 関根和彦
- Industrial Property Rights Holder
  慶應義塾
- Industrial Property Number
  2004-145971
- Filing Date
  2004-05-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Presentation] Cytokine and other mediator responses in the phase of fluid shift following burn injury2007
- Author(s)
  Aikawa, N
- Organizer
  42nd World Congress of the International Society of Surgery ISS/SIC
- Place of Presentation
  Montreal, Canada
- Year and Date
  2007-08-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390482
[Presentation] Cytokine and other mediator responses in the phase of fluid shift following burn injury2007
- Author(s)
  Aikawa N
- Organizer
  42nd World Congress of the International Society of Surgery ISS/SIC
- Place of Presentation
  Montreal,Canada
- Year and Date
  2007-08-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390482

1. HORI Shingo (80129650)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. FUJISHIMA Seitaro (00173419)

# of Collaborated Projects: 4 results

# of Collaborated Products: 28 results
3. SEKINE Kazuhiko (90296715)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
4. TOMITA Yutaka (50112694)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. AOKI Katsunori (20124927)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
6. YOH Kikuo (00327644)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
7. MIYATAKE Satoru (00306812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ISHIBIKI Kyuya (10051236)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ANDO Nobutoshi (90101972)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. UEDA Masakazu (50142419)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 山崎元靖 (00296716)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KIMURA Hiroyuki (00225054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SUZUKI Masaru (70265916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKAMURA Iwao (60265808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NISHINA Masayoshi (20180622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MIYAKI Masaru (60365400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. WAKABAYASHI Go (50175064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ABE Osahiko (90051028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SHIMIZU Nobuyoshi (50162706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 堀口崇 (70245520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 篠沢洋太郎 (30129465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 並木淳 (20189195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 小沢壮治 (10169287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 下山豊

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SHIMOYAMA Yutaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AIKAWA Naoki 相川 直樹

Research Projects

Research Products

Co-Researchers

Immunological and metabolic changes induced by severe insults : insights into its pathophysiology and a development of new therapiesPrincipal Investigator

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入浴中急死(熱中症)の防止対策:免疫修飾による治療戦略の検討

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Sudden death during bating: cardiovascular collapse by experimental hyperthermia

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Analysis of altered immunological responses under abnormal environmental conditions, including environmental temperature, and the trial of its active modulation for the treatment of critically ill patientsPrincipal Investigator

Principal Investigator

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An experimental study on hypotensive resuscitation of near-lethal uncontrolled hemorrhage : Effects on tissue dysoxia, mortality and end-organ function at 72 hours

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Identification of cause of sudden death during hot waterbathing

Principal Investigator

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Biomedical responses to changes in body temperature in ciritically ill patientsPrincipal Investigator

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Experimental Study of Cell Growth Factors on Tissue Repair

Principal Investigator

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Pharmacokinetic changes of antibiotics by surgical stress and their clinical role

Principal Investigator

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Experimental and Clinical Study for Atrial Natriuretic Hormone and Hemodynamics on Surgical StressPrincipal Investigator

Principal Investigator

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[Book] 深在性真菌症の診断・治療ガイドライン20072007

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[Book] 救急救命士標準テキスト2007

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[Book] MRSA-基礎・臨床・対策-2006

Author(s)

Total Pages

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Data Source

[Book] 敗血症の解明と治療戦略2006

Author(s)

AIKAWA Naoki 相川直樹