KONO Tosihiro 向野利寛

… Alternative Names

向野利寛コウノトシヒロ

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Researcher Number	40117106
Other IDs
Affiliation (based on the past Project Information) *help	2012 – 2017: 福岡大学, 医学部, 教授 2010: 福岡大学, 筑紫病院, 教授 2008 – 2009: 福岡大学, 医学部, 教授
Review Section/Research Field	Except Principal Investigator Ophthalmology
Keywords	Except Principal Investigator SHG顕微鏡 / 原田病 / 硝子体濃度 / 血清濃度 / 血管新生モデル / 網膜下線維化 / 炎症性眼疾患 / 視神経炎 / SEMA4A / 線維化 … More / 走査電子顕微鏡 / レーザー脈絡膜新生血管モデル / コラーゲンリモデリング / テナシンＣ / コラーゲン可視化 / 増殖性網膜症 / 増殖糖尿病網膜症 / 牽引性網膜剥離 / テナシンC / ペリオスチン / リモデリング / コラーゲン / SHG光 / 網膜色素上皮細胞 / 眼増殖性疾患 / マイクロアレイ / 遺伝子発現 / 増殖硝子体網膜症 / ゲノム医科学 Less

The serum concentration of SEMA4A in eye diseases
- Principal Investigator
  
  Yukio Sassa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyushu University
  Fukuoka University
An effective screening for proliferative vitreoretinopathy-associated genes
- Principal Investigator
  
  SASSA, Yukio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Fukuoka University
Microarray analysis of proliferative vitreoretinopathy to identify molecular targets for new diagnosis and therapy
- Principal Investigator
  
  YOSHIDA Shigeo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Fukuoka University

All 2016 2015 2014 2013 2012 2010 Other

All Journal Article Presentation Book

[Book] Advances in Medicine and Biology. Volume 532012
- Author(s)
  Yukio Sassa, Atsunobu Takeda, Shigeo Yoshida, Yo-ichi Kawano, Toshihiro Kono, Tatsuro Ishibashi
- Publisher
  Nova Science Publishers, Inc
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] The Kinetics of VEGF and MCP-1 in the Second Vitrectomy Cases with Proliferative Diabetic Retinopathy.2016
- Author(s)
  Yukio Sassa, Shigeo Yoshida, Keijiro Ishikawa, Ryo Asato, Tatsuro Ishibashi and Toshihiro Kono
- Journal Title
  
  Eye
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10912
[Journal Article] The kinetics of VEGF and MCP-1 in the second vitrectomy cases with proliferative diabetic retinopathy.2016
- Author(s)
  Sassa Y,Yoshida S, Ishikawa K, Asato R, Ishibashi T, Kono T
- Journal Title
  
  Eye (Lond).
  
  Volume: 30 Pages: 746-53
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10912
[Journal Article] Increased vitreous concentrations of MCP-1 and IL-6 after vitrectomy in patients with proliferative diabetic retinopathy: Possible relation to postoperative macular edema2015
- Author(s)
  Kubo Y, Kobayashi Y, Zhou Y, Nakama T, Yamaguchi M, Tachibana T, Ishikawa K, Arita R, Nakao S, Sassa Y, Oshima Y, Kono T, Ishibashi T.
- Journal Title
  
  Br J Ophthalmol.
  
  Volume: 99(7) Pages: 960-966
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10912
[Journal Article] 糖尿病患者の管理 (網膜症）2015
- Author(s)
  向野利寛、佐々　由季生
- Journal Title
  
  臨床と研究
  
  Volume: ９２（１） Pages: 63-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] Microarray analysis of gene expression in fibrovascular membranes excised from patients with proliferative diabetic retinopathy.2015
- Author(s)
  Ishikawa K, Yoshida S, Kobayashi Y, Zhou Y, Nakama T, Nakao S, Sassa Y, Oshima Y, Niiro H, Akashi K, Kono T, Ishibashi T.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 56(2) Pages: 932-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] Increased Expression of M-CSF and IL-13 in Vitreous of Patients with Proliferative Diabetic Retinopathy: Implications for M2 Macrophage-involving Fibrovascular Membrane Formation2015
- Author(s)
  Shigeo Yoshida, Yoshiyuki Kobayashi, Takahito Nakama, Yedi Zhou, Keijiro Ishikawa, Ryoichi Arita, Shintaro Nakao, Masanori Miyazaki, Yukio Sassa, Yuji Oshima, Kenji Izuhara, Toshihiro Kono, and Tatsuro Ishibashi
- Journal Title
  
  Br J Ophthalmol.
  
  Volume: 99(5) Pages: 629-634
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10912
[Journal Article] 増殖糖尿病網膜症に対する硝子体手術10年後視力予後因子の統計学的検討―増殖糖尿病網膜症長期視力予後因子―2015
- Author(s)
  佐々　由季生、秋山　雅人、吉田茂生、佐伯　有祐、高橋　理恵、光武　智子、向野　利寛
- Journal Title
  
  臨床眼科
  
  Volume: 69(8) Pages: 1269-1275
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10912
[Journal Article] 増殖糖尿病網膜症に対する硝子体手術10年後視力予後因子の統計学的検討2015
- Author(s)
  佐々　由季生、秋山　雅人、吉田茂生、佐伯　有祐、高橋　理恵　光武　智子　向野　利寛
- Journal Title
  
  臨床眼科
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] Overexpression of CD163 in vitreous and fibrovascular membranes of patients with proliferative diabetic retinopathy: possible involvement of periostin.2015
- Author(s)
  Kobayashi Y, Yoshida S, Nakama T, Zhou Y, Ishikawa K, Arita R, Nakao S, Miyazaki M, Sassa Y, Oshima Y, Izuhara K, Kono T, Ishibashi T
- Journal Title
  
  Br J Ophthalmol.
  
  Volume: 99(4) Pages: 451-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] Increased vitreous concentrations of MCP-1 and IL-6 after vitrectomy in patients with proliferative diabetic retinopathy: possible association with postoperative macular oedema.2015
- Author(s)
  Yoshida S, Kubo Y, Kobayashi Y, Zhou Y, Nakama T, Yamaguchi M, Tachibana T, Ishikawa K, Arita R, Nakao S, Sassa Y, Oshima Y, Kono T, Ishibashi T.
- Journal Title
  
  Br J Ophthalmol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] Overexpression of CD163 in vitreous and fibrovascular membranes of patients with proliferative diabetic retinopathy: possible involvement of periostin.2015
- Author(s)
  Kobayashi Y, Yoshida S, Nakama T, Zhou Y, Ishikawa K, Arita R, Nakao S, Miyazaki M, Sassa Y, Oshima Y, Izuhara K, Kono T, Ishibashi T
- Journal Title
  
  Br J Ophthalmol.
  
  Volume: 99(4) Pages: 451-456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10912
[Journal Article] Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy.2014
- Author(s)
  Ishikawa K, Yoshida S, Nakao S, Nakama T, Kita T, Asato R, Sassa Y, Arita R, Miyazaki M, Enaida H, Oshima Y, Murakami N, Niiro H, Ono J, Matsuda A, Goto Y, Akashi K, Izuhara K, Kudo A, Kono T, Hafezi-Moghadam A, Ishibashi T.
- Journal Title
  
  FASEB J
  
  Volume: 28 Pages: 131-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] Comparison of gene expression profile of epiretinal membranes obtained from eyes　with proliferative vitreoretinopathy to that of secondary epiretinal membranes.2013
- Author(s)
  Asato R, Yoshida S, Ogura A, Nakama T, Ishikawa K, Nakao S, Sassa Y, Enaida H, Oshima Y, Ikeo K, Gojobori T, Kono T, Ishibashi T.
- Journal Title
  
  PLoS One
  
  Volume: 8(1)
- NAID
  120005227330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] Comparison of Gene Expression Profile of Epiretinal Membranes Obtained from Eyes with Proliferative Vitreoretinopathy to That of Secondary Epiretinal Membranes2013
- Author(s)
  Asato R, Yoshida S,Ogura A, Nakama T,Ishikawa K, Nakao S, Sassa Y, Enaida H, Oshima Y, Ikeo K, Gojobori T, Kono T, Ishibashi　T
- Journal Title
  
  Plos One
  
  Volume: 10
- NAID
  120005227330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] 毛様体扁平部濾過手術を施行した血管新生緑内障の術後成績の検討2012
- Author(s)
  佐伯有祐　佐々由季生　安里　良　向野利寛
- Journal Title
  
  眼科手術
  
  Volume: 25 Pages: 577-581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] Aniti-angiogenic shift in vitreous after vitrectomy in patients with proliferative diabetic retinopathy2012
- Author(s)
  Yoshida S, Nakama T, Ishikawa K, Arima M, Tachibana T, Nakao S, Sassa Y, Yasuda M, Enaida H, Oshima Y, Kono T, Ishibashi T.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 53 Pages: 6997-7003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592687
[Journal Article] Gene expression profile of fibrovascular membranes from patients with proliferative diabetic retinopathy.2010
- Author(s)
  Yoshida S, Ogura A, Ishikawa K, Yoshida A, Kohno R, Yamaji Y, Ikeo K, Gojobori T, Kono T, Ishibashi T.
- Journal Title
  
  Br J Ophthalmol.
  
  Volume: 94 Pages: 795-801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592066
[Journal Article] Reduced concentrations of angiogenesis-related factors in vitreous after vitrectomy in patients with proliferative diabetic retinopathy.2010
- Author(s)
  Yoshida S, Ishikawa K, Matsumoto T, Yoshida A, Ishibashi T, Kono T.
- Journal Title
  
  Graefes Arch Clin Exp Ophthalmol.
  
  Volume: 248 Pages: 799-804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592066
[Journal Article] Reduced concentrations of angiogenesis-related factors in vitreous after vitrectomy in patients with proliferative diabetic retinopathy.2010
- Author(s)
  Yoshida S, Ishikawa K, Matsumoto T, Yoshida A, Ishibashi T, Kono T
- Journal Title
  
  Graefes Arch Clin Exp Ophthalmol 248
  
  Pages: 799-804
- Data Source
  KAKENHI-PROJECT-20592066
[Presentation] Ten-year visual outcome following vitreous surgery for proliferative diabetic retinopathy2015
- Author(s)
  Yukio Sassa, Shigeo Yoshida, Masato Akiyama, Yusuke Saeki, Rie Takahashi, Tatsuro Ishibashi, Toshihiro Kono
- Organizer
  The ８th Joint Meeting of Korea-China-Japan
- Place of Presentation
  福岡市
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10912
[Presentation] 網膜剥離症例に対するHeavySILTMの使用経験2014
- Author(s)
  佐々　由季生　高橋　理恵　光武　智子　佐伯　有祐　向野　利寛
- Organizer
  第41回　福岡大学眼科研究会
- Place of Presentation
  福岡
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-24592687
[Presentation] Increased Concentrations of Periostin in the Vitreous of Proliferative Diabetic Retinopathy Patients with Tractional Retinal Detachment.2013
- Author(s)
  Rie Takahashi, Yukio Sassa, Shigeo Yoshida, Yusuke Saeki, Tatsuro Ishibashi, Toshihiro Kono
- Organizer
  The 8th Asia Pacific Vitreo-Retina Society Congress
- Place of Presentation
  Nagoya, Ja
- Data Source
  KAKENHI-PROJECT-24592687
[Presentation] The significant relationships between Fibronectin, Tenascin-C and Periostin in the eyes of the patients with diabetic retinopathy2013
- Author(s)
  Yukio Sassa; Shigeo Yoshida; Keijiro Ishikawa; Ryo Asato; Mitsuru Arima; Masanori Miyazaki; Hiroshi Enaida; Yuji Oshima; Toshihiro Kono; Tatsuro Ishibashi
- Organizer
  ARVO annual meeting
- Place of Presentation
  Seatle, U.S.A
- Data Source
  KAKENHI-PROJECT-24592687
[Presentation] 第2高調波発生光（SHG光）顕微鏡を用いたコラーゲン線維再構築の経時的変化2012
- Author(s)
  佐々　由季生、吉田　茂生、福島　修一郎、斉藤　徹也、田仲亮介、藤澤　一樹、石川　桂二郎、安里　良、有馬　充、向野　利寛、安井　武史、荒木　勉、石橋　達朗
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24592687
[Presentation] New method for evaluating 3D collagen remodeling by SHG microscope2012
- Author(s)
  Yukio Sassa, Shigeo Yoshida , Shuichiro Fukushima , Tetsuya Saito, Keijiro Ishikawa, Toshihiro Kono, Tatsuro Ishibashi, Takeshi Yasui, Tsutomu Araki
- Organizer
  The 5th Joint Meeting of Korea-China-Japan Ophthalmologists
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-24592687
[Presentation] 最近2年間の増殖糖尿病網膜症に対する硝子体手術成績2010
- Author(s)
  吉田茂生, 松本時子, 鍋島崇寛, 野田美登利, 佐伯有祐, 向野利寛
- Organizer
  九州眼科学会
- Place of Presentation
  佐賀市
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-20592066
[Presentation] 増殖糖尿病網膜症の硝子体手術前後の硝子体中VEGFの低下:同一症例での検討2010
- Author(s)
  吉田茂生, 石川桂二郎, 向野利寛, et al
- Organizer
  日本網膜硝子体学会
- Place of Presentation
  大阪市
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20592066
[Presentation] 増殖糖尿病網膜症の硝子体手術前後の硝子体中VEGFの低下:同一症例での検討2010
- Author(s)
  吉田茂生, 石川桂二郎, 向野利寛, et al.
- Organizer
  日本網膜硝子体学会
- Place of Presentation
  大阪市
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20592066
[Presentation] Reduced concentrations of VEGF in vitreous after vitrectomy in patientswith proliferative diabetic retinopathy.2010
- Author(s)
  Yoshida S, Ishikawa K, Yukio S, Ryo A, Ayako Y, Kono T
- Organizer
  The Third Joint Meeting of Korea-China-Japan Ophthalmologists
- Place of Presentation
  Beijing
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-20592066
[Presentation] Reduced concentrations of VEGF in vitreous after vitrectomy in patients with proliferative diabetic retinopathy.2010
- Author(s)
  Yoshida S, Ishikawa K, Yukio S, Ryo A, Ayako Y, Kono T
- Organizer
  In : The Third Joint Meeting of Korea-China-Japan Ophthalmologists
- Place of Presentation
  Beijing
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-20592066
[Presentation] 増殖糖尿病網膜症にともなう線維血管増殖組織におけるペリオスチンの発現上昇2010
- Author(s)
  吉田茂生, 石川桂二郎, 樋口直美, 向野利寛, 石橋達朗
- Organizer
  第114回日本眼科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2010-04-15
- Data Source
  KAKENHI-PROJECT-20592066
[Presentation] The concentration changes of VEGF and MCP-1 in the eyes of the patientswith proliferative diabetic retinopathy.(The second vitrectomy cases)2010
- Author(s)
  Yoshida S, Sassa Y, Asato R, Ishikawa K, Saeki Y, Kono T
- Organizer
  The Third Joint Meeting of Korea-China-Japan Ophthalmologists
- Place of Presentation
  Beijing
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-20592066
[Presentation] The concentration changes of VEGF and MCP-1 in the eyes of the patients with proliferative diabetic retinopathy.2010
- Author(s)
  Yoshida S, Sassa Y, Asato R, Ishikawa K, Saeki Y, Kono T
- Organizer
  (The second vitrectomy cases). The Third Joint Meeting of Korea-China-Japan Ophthalmologists
- Place of Presentation
  Beijing
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-20592066
[Presentation] 増殖糖尿病網膜症術前・術後因子の術10年後視力へ与える影響について統計学的解析
- Author(s)
  佐々由季生、佐伯有祐、高橋理恵、光武智子、向野利寛
- Organizer
  第53回日本網膜硝子体学会総会
- Place of Presentation
  大阪
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-24592687

1. YOSHIDA Shigeo (50363370)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
2. ISHIBASHI Tatsuro (30150428)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
3. SASSA, Yukio (80580315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
4. FUKUSHIMA Syuuichiro (40362644)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. YASUI Takeshi (70314408)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. KONO Toshihiro (40161880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 奥野龍禎 (00464248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KONO Tosihiro 向野 利寛

向野 利寛 コウノ トシヒロ

Research Projects

Research Products

Co-Researchers

The serum concentration of SEMA4A in eye diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An effective screening for proliferative vitreoretinopathy-associated genes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Microarray analysis of proliferative vitreoretinopathy to identify molecular targets for new diagnosis and therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Advances in Medicine and Biology. Volume 532012

Author(s)

Publisher

Data Source

[Journal Article] The Kinetics of VEGF and MCP-1 in the Second Vitrectomy Cases with Proliferative Diabetic Retinopathy.2016

Author(s)

Journal Title

Data Source

[Journal Article] The kinetics of VEGF and MCP-1 in the second vitrectomy cases with proliferative diabetic retinopathy.2016

Author(s)

Journal Title

Data Source

[Journal Article] Increased vitreous concentrations of MCP-1 and IL-6 after vitrectomy in patients with proliferative diabetic retinopathy: Possible relation to postoperative macular edema2015

Author(s)

Journal Title

Data Source

[Journal Article] 糖尿病患者の管理 (網膜症）2015

Author(s)

Journal Title

Data Source

[Journal Article] Microarray analysis of gene expression in fibrovascular membranes excised from patients with proliferative diabetic retinopathy.2015

Author(s)

Journal Title

Data Source

[Journal Article] Increased Expression of M-CSF and IL-13 in Vitreous of Patients with Proliferative Diabetic Retinopathy: Implications for M2 Macrophage-involving Fibrovascular Membrane Formation2015

Author(s)

Journal Title

Data Source

[Journal Article] 増殖糖尿病網膜症に対する硝子体手術10年後視力予後因子の統計学的検討―増殖糖尿病網膜症長期視力予後因子―2015

Author(s)

Journal Title

Data Source

[Journal Article] 増殖糖尿病網膜症に対する硝子体手術10年後視力予後因子の統計学的検討2015

Author(s)

Journal Title

Data Source

[Journal Article] Overexpression of CD163 in vitreous and fibrovascular membranes of patients with proliferative diabetic retinopathy: possible involvement of periostin.2015

Author(s)

Journal Title

Data Source

[Journal Article] Increased vitreous concentrations of MCP-1 and IL-6 after vitrectomy in patients with proliferative diabetic retinopathy: possible association with postoperative macular oedema.2015

Author(s)

Journal Title

Data Source

[Journal Article] Overexpression of CD163 in vitreous and fibrovascular membranes of patients with proliferative diabetic retinopathy: possible involvement of periostin.2015

Author(s)

Journal Title

Data Source

[Journal Article] Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy.2014

Author(s)

Journal Title

Data Source

[Journal Article] Comparison of gene expression profile of epiretinal membranes obtained from eyes with proliferative vitreoretinopathy to that of secondary epiretinal membranes.2013

Author(s)

Journal Title

NAID

Data Source

KONO Tosihiro 向野利寛

向野利寛コウノトシヒロ

[Journal Article] Comparison of gene expression profile of epiretinal membranes obtained from eyes　with proliferative vitreoretinopathy to that of secondary epiretinal membranes.2013

[Presentation] 増殖糖尿病網膜症の硝子体手術前後の硝子体中VEGFの低下:同一症例での検討2010