SASAKI SHOICHI 佐々木彰一

… Alternative Names

SASAKI Shoichi 佐々木彰一

佐々木彰一ササキショウイチ

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Researcher Number	40119962
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2010 – 2014: 東京女子医科大学, 医学部, 准教授 2007 – 2008: Tokyo Women's Medical University, 医学部, 准教授 2006: 東京女子医科大学, 医学部, 助教授 2002 – 2004: 東京女子医科大学, 医学部, 助教授 1999 – 2000: 東京女子医科大学, 医学部, 講師 … More 1996: 東京女子医科大学, 医学部, 講師 1992 – 1994: 東京女子医科大学, 医学部, 講師 1990 – 1991: 東京女子医科大学, 医学部, 助手 1989: 東京女子医科大学, 神経内科, 助手 1989: 東京女子医科大学, 脳神経センター・神経内科, 助手 1988: 東京女子医科大学, 脳神経センター神経内科, 助手 Less
Review Section/Research Field	Principal Investigator Neurology / Neurology / Nerve anatomy/Neuropathology Except Principal Investigator Neurology
Keywords	Principal Investigator 筋萎縮性側索硬化症 / 超微細構造 / シナプス / 脊髄前角細胞 / SOD1 / ミトコンドリア / 運動ニューロン疾患 / initial segment / axon hillock / active zone … More / EAAT2 / EAAT1 / SOD1変異 / amyotrophic lateral sclerosis / proximal axon / 軸索輸送 / 病理 / 電子顕微鏡 / 脊髄 / 変異SOD1導入マウス / 軸索 / immuno-electron microscopy / electron microscopy / aggregate / mitochondria / axonal transport / mutant SOD1 transgenic mice / electrom microscopy / G93A SOD1変異マウス / 変異マウス / aggregates / G93A変異SOD1導入マウス / 免疫電顕 / 電顕 / 凝集体 / spinal cord / nitrotyrosine / iNOS / transgenic mice / SOD1 mutation / ALS / 免疫組織 / グルタミン酸トランスポーター / 免疫組織学 / nitric oxide synthase / SCDI変異 / トランスジュニックマウス / 筋萎縮性側素硬化症 / ニトロタイロシン / NOS / トランスジェニックマウス / Ultrastructure / Neurofilament / Axonal transport / Axonalinitial Segment / Proximal axon / Anterior horn neuron / Motor neuron disease / Amyotrophic lateral sclerosis / dendrite / axon / ultrastructure / 筋妥縮性側索硬化症 / 超微装構造 / ニュ-ロフィラメント / axonal initial segment / 近位部軸索 / 運動ニュ-ロン疾患 / 粗面小胞体 / TDP-43 / P62 / 核内空胞変化 / コンデショナルADAR2ノックアウトマウス / GluA2 / p62 / LC3 / autophagosome / autolysosome / AMPA受容体 / ADAR2-knockout マウス / フィブリノーゲン / 癒着帯 / 血液ー脊髄関門 / コンディショナルTDP-43ノックアウトマウス / 血液-脊髄関門 / カルシウム / ADAR2-ノックアウトマウス / RNA 編集 / AMPA 受容体 / TDP-43 ノックアウトマウス / オートファジー / 運動ニューロン / 封入体 / 後根神経節 / 脊髄前角 / 活動帯 / Betz巨細胞 / 大脳皮質運動野 / 樹状突起 … More Except Principal Investigator platelet aggregation / beta-amyloid protein / tau-protein / VEP / P300 / vasopressin / multi-imfarct dementia / Alzheimer disease / MRI / Pick病 / nucleus basalis of Mynert / CT / 髄液AVP / DDAVDの点鼻療法 / Alzheiner型痴呆 / Thyrotropin releasing hormone / Tyrotropin releasing hormone / 髄液バゾプレッシン(AVP) / Alzheimer型痴呆 / 図形反転誘発電位 / 聴性脳幹反応 / 事象関連電位 / 血小板凝集 / βーアミロイド蛋白 / タウ蛋白 / 視覚誘発電位 / P_<300> / バゾプレッシン / 多発梗塞性痴呆 / アルツハイマ-病 Less

elucidation of pathomechanism in sporadic ALSPrincipal Investigator
- Principal Investigator
  
  SASAKI SHOICHI
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Women's Medical University
Neuropathological study of amyotrophic lateral sclerosis and mutant SOD1 transgenic micePrincipal Investigator
- Principal Investigator
  
  SASAKI Shoichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Women's Medical University
Pathological study of mutant SOD1 (G93A and H46R) transgenic micePrincipal Investigator
- Principal Investigator
  
  SASAKI Shoichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Women's Medical University
EAAT1 and EAAT2 immunoreactivity in ALS and pathology of SOD1 (G93A) transgenic micePrincipal Investigator
- Principal Investigator
  
  SASAKI Shoichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Women's Medical University
筋萎縮性側索硬化症の大脳皮質運動野におけるシナプスの検討Principal Investigator
- Principal Investigator
  
  佐々木彰一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Women's Medical University
筋萎縮性側索硬化症における脊髄前角細胞の樹状突起のシナプスの変化についてPrincipal Investigator
- Principal Investigator
  
  佐々木彰一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Women's Medical University
筋萎縮性側索硬化症における脊髄前角細胞の近位部軸率のシナプスの変化についてPrincipal Investigator
- Principal Investigator
  
  佐々木彰一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Women's Medical University
筋萎縮性側索硬化症における脊髄前角細胞のシナプスの変化についてPrincipal Investigator
- Principal Investigator
  
  佐々木彰一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Women's Medical University
Study of the proximal axon of anterior horn neurons in amyotrophic lateral sclerosisPrincipal Investigator
- Principal Investigator
  
  SASAKI Shoichi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Women's Medical College
Studies on the determination of etiology of dementia and development of new diagnostic methods, therapies and drugs.
- Principal Investigator
  
  MARUYAMA Shoichi
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Women's Medical University

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004 2002 Other

All Journal Article Presentation Book

[Book] ガイドライン外来診療20142014
- Author(s)
  佐々木彰一
- Total Pages
  679
- Publisher
  日経メディカル開発
- Data Source
  KAKENHI-PROJECT-22590965
[Book] イヤーノート 2015 24版2014
- Author(s)
  佐々木彰一
- Total Pages
  1687
- Publisher
  メディクメディア社
- Data Source
  KAKENHI-PROJECT-22590965
[Book] すべてがわかるALS・運動ニューロン疾患2013
- Author(s)
  佐々木彰一
- Total Pages
  370
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-22590965
[Book] 今日の神経疾患治療指針　第２版。ボツリヌス中毒。2013
- Author(s)
  佐々木彰一
- Total Pages
  1100
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22590965
[Book] 神経内科学ノート　国試から臨床まで。2013
- Author(s)
  佐々木彰一
- Total Pages
  191
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22590965
[Book] 神経内科学ノート　国試から臨床まで2013
- Author(s)
  佐々木彰一
- Total Pages
  191
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22590965
[Book] 今日の神経疾患治療指針　第２版2013
- Author(s)
  佐々木彰一
- Total Pages
  1100
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22590965
[Book] ガイドライン　外来診療　2012。顔面神経麻痺。2012
- Author(s)
  佐々木彰一
- Total Pages
  619
- Publisher
  日経メディカル開発
- Data Source
  KAKENHI-PROJECT-22590965
[Book] Methods in molecular biology volume on “Protein misfolding and cellular stress in disease and ageing. "2009
- Author(s)
  Sasaki S
- Publisher
  The Humana Press Inc(In press)
- Data Source
  KAKENHI-PROJECT-18500280
[Book] 筋萎縮性側索硬化症の近況.Year note series. Selected articles.(2010岡庭豊編)2009
- Author(s)
  佐々木彰一
- Publisher
  メディクメディア社,東京
- Data Source
  KAKENHI-PROJECT-18500280
[Book] 言語聴覚士のための基礎知識。臨床神経学・高次脳機能障害学。2006
- Author(s)
  佐々木彰一
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-18500280
[Book] 整形外科診療実践ガイド2006
- Author(s)
  佐々木彰一
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-18500280
[Book] 筋萎縮性側索硬化症. 「整形外科診療実践ガイド」(守屋秀繁、糸満盛憲、内田淳正、荻野利彦、黒坂昌弘、戸山芳昭編集)2006
- Author(s)
  佐々木彰一
- Publisher
  文光堂、東京
- Data Source
  KAKENHI-PROJECT-18500280
[Book] イヤーノート2004
- Author(s)
  佐々木彰一
- Total Pages
  1517
- Publisher
  メディックメディア社
- Data Source
  KAKENHI-PROJECT-14570623
[Book] Annual Review 神経2002
- Author(s)
  佐々木彰一
- Total Pages
  352
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Book] 老化. サブテキスト神経学
- Author(s)
  佐々木彰一
- Publisher
  医学書院(印刷中)
- Data Source
  KAKENHI-PROJECT-18500280
[Book] 神経症状と検査異常。8.1) 症状。6. 筋萎縮・筋力低下。チャート病態内科診断学
- Author(s)
  佐々木彰一
- Publisher
  中外医学社(印刷中)
- Data Source
  KAKENHI-PROJECT-18500280
[Book] Protein misfolding and cellular stress in disease and ageing -Concepts and Protocols
- Author(s)
  Sasaki S
- Publisher
  Determination of altered mitochondria ultrastructure by electron microscopy(Methods in Molecular Biology. (ed.J. Walker). Humana Press/Springer. (in press))
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] The effect of an uninterrupted switch from donepezil to galantamine without dose titration on BPSD in Alzheimer disease2014
- Author(s)
  Sasaki Shoichi, et al
- Journal Title
  
  Dementia and Geriatric Cognitive Disorders EXTRA
  
  Volume: - Issue: 2 Pages: 131-139
- DOI
  10.1159/000362871
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22590965
[Journal Article] Unique nuclear vacuoles in the motor neurons of conditional ADAR2-knockout mice2014
- Author(s)
  Sasaki S, Yamashita T, Hideyama T, Kwak S
- Journal Title
  
  Brain Research
  
  Volume: 1550 Pages: 36-46
- DOI
  10.1016/j.brainres.2014.01.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22590965, KAKENHI-PUBLICLY-25110709, KAKENHI-PROJECT-25253063, KAKENHI-PROJECT-25461269, KAKENHI-PROJECT-26640036
[Journal Article] Dendritic retraction, but not atrophy, is consistent in amyotrophic lateral sclerosis-comparison between Onuf’s neurons and other sacral motor neurons.2014
- Author(s)
  Takeda T, Uchihara T, Nakayama Y, Nakamura A, Sasaki, S et al
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 2 Issue: 1 Pages: 11-11
- DOI
  10.1186/2051-5960-2-11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22590965, KAKENHI-PROJECT-25293449, KAKENHI-PROJECT-25430057, KAKENHI-PROJECT-25463393, KAKENHI-PROJECT-25463459
[Journal Article] Autophagy in spinal cord motor neurons in sporadic amyotrophic lateral sclerosis2011
- Author(s)
  Shoichi Sasaki
- Journal Title
  
  Journal of Neuropathology and Experimental Neurology
  
  Volume: 70 Pages: 349-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590965
[Journal Article] Endoplasmic reticulum stress in motor neurons of the spinal cord in sporadic amyotrophic lateral sclerosis2010
- Author(s)
  Shoichi Sasaki
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 69 Pages: 346-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590965
[Journal Article] Determination of altered mitochondria ultrastructure by electron microscopy.2010
- Author(s)
  Shoichi Sasaki
- Journal Title
  
  Methods Mol Biol
  
  Volume: 684 Pages: 279-290
- Data Source
  KAKENHI-PROJECT-22590965
[Journal Article] Alterations in subcellular localization of TDP-43 immunoreactivity in the anterior horns in sporadic amyotrophic lateral sclerosis2010
- Author(s)
  S.Sasaki, et al
- Journal Title
  
  Neurosci Lett
  
  Volume: 478 Pages: 72-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590965
[Journal Article] Mitochondrial alterations in transgenic mice with an H46R mutant SOD1 gene.2009
- Author(s)
  Sasaki S, Aoki M, Nagai M, Kobayashi M, Itoyama Y.
- Journal Title
  
  Journal of Neuropathology and Experimental Neurology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Mitochondrial alterations in transgenic mice with an H46R mutant SOD1 gene2009
- Author(s)
  Sasaki S, Aoki M, Nagai M, Kobayashi M, Itoyama Y.
- Journal Title
  
  J Neuropathol Exp Neurol 68
  
  Pages: 365-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Activation of signal transducer and activator of transcription-3 in the spinal cord of sporadic amyotrophic lateral sclerosis patients.2009
- Author(s)
  Shibata N, Kakita, A, Takahashi H, Ihara Y, Nobukuni K, Fujimura H, Sakoda S, Sasaki S, et al
- Journal Title
  
  Neurodegenerative Diseases (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Activation of signal transducer and activator of transcription-3 in the spinal cord of sporadic amyotrophic lateral sclerosis2009
- Author(s)
  Shibata N, Kakita A, Takahashi H, Ihara Y, Nobukuni K, Fujimura H, Sakoda S, Sasaki S, et.al.
- Journal Title
  
  Neurodegener Dis 6
  
  Pages: 118-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Involvement of the spinal motor neurons in parkin-positive autosomal recessive juvenile parkinsonism2008
- Author(s)
  Sasaki S, Shirata A, Yamane K, Iwata M.
- Journal Title
  
  Neuropathology 28
  
  Pages: 74-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] 筋萎縮性側索硬化症の臨床病型2008
- Author(s)
  佐々木彰一
- Journal Title
  
  東女医大誌 78
- NAID
  110007524776
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] 「ALS-臨床と研究の最新情報」孤発性ALS古典型臨床症候と経過2008
- Author(s)
  佐々木彰一
- Journal Title
  
  Clinical Neuroscience 26
  
  Pages: 268-269
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] アテローム塞栓症による脊髄梗塞2008
- Author(s)
  橋詰良夫、汪寅、佐々木彰一
- Journal Title
  
  脊椎脊髄ジャーナル 21
  
  Pages: 95-98
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Involvement of the spinal motor neurons in parkin-positive autosomal recessive juvenile Parkinsonism.2008
- Author(s)
  Sasaki S, Shirata A, Yamane K, Iwata M
- Journal Title
  
  Neuropatholgy 28
  
  Pages: 74-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Protein-bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase-1 mutation-associated familial amyotrophic lateral sclerosis and its transgenic mouse model2007
- Author(s)
  Shibata N, Kawaguchi M, Uchida K, Kakita A, Takahashi H, Sasaki S, et.al.
- Journal Title
  
  Neuropathology 27
  
  Pages: 49-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Motor neuron disease in transgenic mice with an H46R mutant SOD1 gene.2007
- Author(s)
  S. Sasaki, et. al.
- Journal Title
  
  J Neuropathol Exp Neurol 66
  
  Pages: 517-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Mitochondrial alterations in the spinal cord of patients with sporadic amyotrophic lateral sclerosis2007
- Author(s)
  Sasaki S, Iwata M.
- Journal Title
  
  J Neuropathol Exp Neurol 66
  
  Pages: 10-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Mitochondrial alterations in dorsal root ganglion cells in sporadic amyotrophic lateral sclerosis.2007
- Author(s)
  S. Sasaki, et. al.
- Journal Title
  
  Acta Neuropathologica 114
  
  Pages: 633-639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Mitochondrial alterations in the spinal cord of patients with sporadic amyotrophic lateral sclerosis.2007
- Author(s)
  S.Sasaki, et al.
- Journal Title
  
  Journal of Neuropathology and Experimental Neurology 66・1
  
  Pages: 10-16
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] 注目される感染症 : 診断と治療の進歩. II. 人獣共通感染症. 5. バリアントCJD2007
- Author(s)
  佐々木彰一
- Journal Title
  
  日本内科学会雑誌 96(11)
  
  Pages: 2423-2428
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Motor neuron disease in transgenic mice with an H46R mutant SOD1 gene2007
- Author(s)
  Sasaki S, Nagai M, Aoki M, Komori T, Itoyama Y, Iwata M.
- Journal Title
  
  J Neuropathol Exp Neurol 66
  
  Pages: 517-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Mitochondrial alterations in dorsal root ganglion cells in sporadic amyotrophic lateral sclerosis2007
- Author(s)
  Sasaki S, Horie Y, Iwata M.
- Journal Title
  
  Acta Neuropathol 114
  
  Pages: 633-639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Mitochondrial alterations in the spinal cord of patients with sporadic amyotrophic lateral sclerosis.2007
- Author(s)
  S. Sasaki and M. Iwata
- Journal Title
  
  J Neuropathol Exp Neurol 66
  
  Pages: 10-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] 「ALS : 研究と診療の進歩」ALSの病型-臨床と病理-2007
- Author(s)
  佐々木彰一
- Journal Title
  
  BRAIN and NERVE 59(10)
  
  Pages: 1013-1021
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] ALS の亜型2006
- Author(s)
  佐々木彰一
- Journal Title
  
  臨床神経学 46(11)
  
  Pages: 825-827
- NAID
  10020347267
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Parvalbumin and ealbindin D-28k immunoreactivity in transgenic mice with a G93A mutant SOD1 gene.2006
- Author(s)
  S.Sasaki, et al.
- Journal Title
  
  Brain Research 1083・1
  
  Pages: 196-203
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] バリアントCJD2006
- Author(s)
  佐々木彰一
- Journal Title
  
  化学療法の領域 22
  
  Pages: 45-50
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Neuronal inclusions in sporadic motor neuron disease are negative for alpha-synuclein2006
- Author(s)
  Sasaki S, Komori T, Iwata M.
- Journal Title
  
  Neurosci Lett 397
  
  Pages: 15-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Parvalbumin and calbindin D-28k immunoreactivity in transgenic mice with a G93A mutant SOD1 gene2006
- Author(s)
  Sasaki S, Warita H, Komori T, Murakami T, Abe K, Iwata M.
- Journal Title
  
  Brain Res 2083
  
  Pages: 196-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Neuronal inclusions in sporadic motor neuron disease are negative for alpha-synuclein.2006
- Author(s)
  S.Sasaki, et al.
- Journal Title
  
  Neuroscience Letters 397・1-2
  
  Pages: 15-19
- Data Source
  KAKENHI-PROJECT-18500280
[Journal Article] Slow axonal transport is impaired in the proximal axon of transgenic mice with a G93A mutant SOD1 gene2004
- Author(s)
  Sasaki S et al.
- Journal Title
  
  Acta Neuropathologica 107
  
  Pages: 452-460
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Accumulation of protein-bound 4-hydroxy-2-hexenal in spinal cords from patients with sporadic amyotrophic lateral sclerosis2004
- Author(s)
  Shibata N, Yamada S, Uchida K.Hirano A, Sakata S, Fujimura H, Sasaki S et al.
- Journal Title
  
  Brain Research 1019
  
  Pages: 170-177
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Ultrastructural study of mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene2004
- Author(s)
  Sasaki S et al.
- Journal Title
  
  Acta Neuropathologica 107
  
  Pages: 461-474
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Parkin-positive autosomal recessive juvenile parkinsonism with α-synuclein-positive inclusions2004
- Author(s)
  S.Sasaki et al.
- Journal Title
  
  Neurology 63
  
  Pages: 678-682
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Microglial activation parallels system degeneration in multiple system atrophy2004
- Author(s)
  Ishizawa K.Komori T, Sasaki S, et al.
- Journal Title
  
  J Neuropathol Exp Neurol 63
  
  Pages: 43-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Slow axonal transport is impaired in the proximal axon of transgenic mice with a G93A mutant SOD1 gene2004
- Author(s)
  Sasaki S et al.
- Journal Title
  
  Acta Neuropathol 107
  
  Pages: 452-460
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Parkin-positive autosomal recessive juvenile parkinsonism with α-synuclein-positive inclusions2004
- Author(s)
  Sasaki S et al.
- Journal Title
  
  Neurology 63
  
  Pages: 678-682
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Ultrastructural study of mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene2004
- Author(s)
  S.Sasaki et al.
- Journal Title
  
  Acta Neuropathologica 107
  
  Pages: 461-474
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Slow axonal transport is impaired in the proximal axon of transgenic mice with a G93A mutant SOD1 gene2004
- Author(s)
  S.Sasaki et al.
- Journal Title
  
  Acta Neuropathologica 107
  
  Pages: 452-460
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Ultrastructural study of mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene2004
- Author(s)
  Sasaki S et al.
- Journal Title
  
  Acta Neuropathol 107
  
  Pages: 461-474
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Ultrastructural study of aggregates in the spinal cord of transgenic mice with a G93A mutant SOD1 gene
- Author(s)
  Sasaki S et al.
- Journal Title
  
  Acta Neuropathol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Ultrastructural study of aggregates in the spinal cord of transgenic mice with a G93A mutant SOD1 gene
- Author(s)
  S.Sasaki et al.
- Journal Title
  
  Acta Neuropathologica (in press)
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Ultrastructural study of aggregates in the spinal cord of transgenic mice with a G93A mutant SOD1 gene
- Author(s)
  Sasaki S et al.
- Journal Title
  
  Acta Neuropathologica (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene
- Author(s)
  Sasaki S et al.
- Journal Title
  
  Acta Neuropathologica (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene
- Author(s)
  S.Sasaki et al.
- Journal Title
  
  Acta Neuropathologica (in press)
- Data Source
  KAKENHI-PROJECT-14570623
[Journal Article] Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene
- Author(s)
  Sasaki S et al.
- Journal Title
  
  Acta Neuropathol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570623
[Presentation] Alterations in the blood-spinal cord barrier in TDP-43 conditional knockout mice2013
- Author(s)
  Sasaki Shoichi, et al
- Organizer
  24th International Symposium on ALS/MND
- Place of Presentation
  Milano
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] コンディショナルADAR2ノックアウトマウスのおけるオートファジーの検討2013
- Author(s)
  佐々木彰一他
- Organizer
  第54回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] Autophagy is involved in spinal motor neuron degeneration in conditional ADAR2-knockout mice2012
- Author(s)
  Sasaki Shoichi
- Organizer
  The 6th International Symposium on Autophagy 2012
- Place of Presentation
  Okinawa
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] コンディショナルADAR2ノックアウトマウスの電顕的検討2012
- Author(s)
  佐々木彰一
- Organizer
  第５４回日本神経学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] Autophagy in the spinal motor neurons of conditional ADAR2-knockout mice2012
- Author(s)
  Sasaki Shoichi
- Organizer
  23rd International Symposium on ALS/MND
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] Ultrastructural study of motor neurons of spinal cords in ADAR2-deficient mice2011
- Author(s)
  Sasaki S, et al
- Organizer
  22^<nd> International symposium on ALS/MND
- Place of Presentation
  Sydney
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] ALSにおけるミトコンドリア異常-形態学的変化について-2011
- Author(s)
  佐々木彰一
- Organizer
  厚労省研究費補助金(難治性疾患克服研究事業)「病態に根ざしたALSの新規治療法開発班」ワークショップ
- Place of Presentation
  東京
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] ALSにおけるオートファジーの関与2011
- Author(s)
  佐々木彰一
- Organizer
  厚労省研究費補助金(難治性疾患克服研究事業)「病態に根ざしたALSの新規治療法開発班」ワークショップ
- Place of Presentation
  東京
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] Autophagy in motor neurons of the spinal cord in sporadic amyotrophic lateral sclerosis2010
- Author(s)
  Shoichi Sasaki
- Organizer
  21^<st> International symposium on ALS/MND
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] 孤発性ALSの脊髄前角におけるTDP-43免疫活性の細胞内分布2009
- Author(s)
  佐々木彰一,武田貴裕、本間温、柴田亮行、小林槇雄、内山真一郎
- Organizer
  第50 回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] 孤発性筋萎縮性側索硬化症の脊髄前角細胞における小胞体の変化2009
- Author(s)
  佐々木彰一,武田貴裕、本間温、内山真一郎
- Organizer
  第50回日本神経病理学会総会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] Mitochondrial alterations in transgenic mice with an H46R mutant SOD1 gene2008
- Author(s)
  Sasaki S, Nagai M, Aoki M, Itoyama Y.
- Organizer
  19^<th> International symposium on ALS/MND
- Place of Presentation
  Birmingham, UK
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] H46R変異SOD1導入マウスのミトコンドリア異常2008
- Author(s)
  佐々木彰一,永井真貴子、青木正志、糸山泰人、岩田誠
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] Mitochondrial alterations in transgenic mice with an H46R mutant SOD1 gene.2008
- Author(s)
  Sasaki S, Nagai M, Aoki M, Itoyama Y.
- Organizer
  19^<th> International symposium on ALS/MND
- Place of Presentation
  Birmingham
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] 孤発性筋萎縮性側索硬化症の後根神経節におけるミトコンドリアの異常2007
- Author(s)
  佐々木彰一,本間温、広井敦子、柴田亮行、小林槇雄、岩田誠
- Organizer
  第48回日本神経病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] Mitochondria in dorsal root ganglion cells are affected in sporadic amyotrophic lateral sclerosis.2007
- Author(s)
  S. Sasaki and M. Iwata
- Organizer
  18th International symposium on ALS/MND.
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] Mitochondria in dorsal root ganglion cells are affected in sporadic amyotrophic lateral sclerosis2007
- Author(s)
  Sasaki S, Iwata M
- Organizer
  18^<th> International symposium on ALS/MND
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] H46R変異SOD1導入マウスの病理像2007
- Author(s)
  佐々木彰一,永井真貴子、青木正志、小森隆司、糸山泰人、岩田誠
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] Neuronal inclusions in sporadic motor neuron disease are negative for alpha-synuclein2006
- Author(s)
  Sasaki S, Iwata M.
- Organizer
  17^<th> International symposium on ALS/MND
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] Neuronal inclusions in sporadic motor neuron disease are negative for alpha-synuclein2006
- Author(s)
  Sasaki S, Iwata M
- Organizer
  XI. International congress on neuromuscular disease
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-18500280
[Presentation] Sporadic lower motor neuron disease with a snake eyes appearance on the cervical anterior horns by MRI: A new clinical subtype?
- Author(s)
  Sasaki S
- Organizer
  24th International symposium on ALS/MND
- Place of Presentation
  ブリュッセル
- Year and Date
  2014-12-06 – 2014-12-08
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] The blood-spinal cord barrier is temporarily impaired in TDP-43
- Author(s)
  Sasaki S, Iguchi Y, Katsuno K, Sobue G
- Organizer
  13th ICNMD
- Place of Presentation
  ニース
- Year and Date
  2014-07-05 – 2014-07-10
- Data Source
  KAKENHI-PROJECT-22590965
[Presentation] TDP-43コンディショナルノックアウトマウスにおける血液脊髄関門の変化
- Author(s)
  佐々木彰一、井口洋平、勝野雅央、祖父江元
- Organizer
  第55回日本神経学会総会
- Place of Presentation
  福岡
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-22590965

1. MARUYAMA Shoichi (60075158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. OSAWA Mikio (60101812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. UCHIYAMA Shinichiro (50119905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MURAKAMI Hirohiko (30120067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KOBAYASHI Isturo (50090527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SASAKI SHOICHI 佐々木 彰一

SASAKI Shoichi 佐々木 彰一

佐々木 彰一 ササキ ショウイチ

Research Projects

Research Products

Co-Researchers

elucidation of pathomechanism in sporadic ALSPrincipal Investigator

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Neuropathological study of amyotrophic lateral sclerosis and mutant SOD1 transgenic micePrincipal Investigator

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Pathological study of mutant SOD1 (G93A and H46R) transgenic micePrincipal Investigator

Principal Investigator

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EAAT1 and EAAT2 immunoreactivity in ALS and pathology of SOD1 (G93A) transgenic micePrincipal Investigator

Principal Investigator

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筋萎縮性側索硬化症の大脳皮質運動野におけるシナプスの検討Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

筋萎縮性側索硬化症における脊髄前角細胞の樹状突起のシナプスの変化についてPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

筋萎縮性側索硬化症における脊髄前角細胞の近位部軸率のシナプスの変化についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

筋萎縮性側索硬化症における脊髄前角細胞のシナプスの変化についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Study of the proximal axon of anterior horn neurons in amyotrophic lateral sclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Studies on the determination of etiology of dementia and development of new diagnostic methods, therapies and drugs.

Principal Investigator

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[Book] ガイドライン外来診療20142014

Author(s)

Total Pages

Publisher

Data Source

[Book] イヤーノート 2015 24版2014

Author(s)

Total Pages

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Data Source

[Book] すべてがわかるALS・運動ニューロン疾患2013

Author(s)

Total Pages

Publisher

SASAKI SHOICHI 佐々木彰一

SASAKI Shoichi 佐々木彰一

佐々木彰一ササキショウイチ

[Book] 今日の神経疾患治療指針　第２版。ボツリヌス中毒。2013

[Book] 神経内科学ノート　国試から臨床まで。2013

[Book] 神経内科学ノート　国試から臨床まで2013

[Book] 今日の神経疾患治療指針　第２版2013

[Book] ガイドライン　外来診療　2012。顔面神経麻痺。2012

[Book] 筋萎縮性側索硬化症の近況.Year note series. Selected articles.(2010岡庭豊編)2009

[Book] 神経症状と検査異常。8.1) 症状。6. 筋萎縮・筋力低下。チャート病態内科診断学