KAMATA Katsuo 鎌田勝雄

Researcher Number	40121496
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011: Hoshi University, 薬学部, 教授 2010: 星薬科大学, 薬科大学, 教授 2009: Hoshi University, 薬学部, 教授 2007: Hoshi University, Faculty of Pharm. Sci., Ph.D. Professor 2006: 星薬科大学, 付置研究所, 教授 … More 2003: 星薬科大学, 教授 2002 – 2003: 星薬科大学, 医薬品化学研究所, 教授 2002: 星薬科大学, 薬学部, 教授 1997 – 2000: 星薬科大学, 医薬品化学研究所, 助教授 1996: 星薬科大学, 医薬品化学研究所・機能形態研究室, 助教授 1994 – 1995: 星薬科大学, 付置研究所, 助教授 1993 – 1995: 星薬科大学, 医薬品化学研究所, 助教授 Less
Review Section/Research Field	Principal Investigator General pharmacology / 応用薬理学・医療系薬学 / Biological pharmacy / General pharmacology Except Principal Investigator General pharmacology / Chemical pharmacy
Keywords	Principal Investigator 内皮細胞 / 糖尿病 / EDHF / エンドセリン-1 / インスリン / endothelin-1 / endothelium / プラゾシン / コレステロール / LDL … More / 高脂血症 / プロスタノイド / ストレプトゾトシン / LDLコレステロール / Ca^<2+> / diabetes / streptozotocin / LDL cholesterol / superoxide anion / 活性酸素 / diabetes mellitus / PPARα / cyclic AMP / AP-1 / AMPK / 弛緩反応 / マウス / 血管 / プラバスタチン / cyclopiazonic acid / 内皮細胞由来弛緩因子 / NO / 内皮細胞由来過分極因子 / NO産生 / AT_1受容体拮抗薬 / RhoA/Rhoキナーゼ / Akt/eNOS / 雌雄差 / エンドセリンー1 / エンドセリン受容体 / PDK / Akt / eNOS / ERK / Nf-κB / スーパーオキドジスムターゼ / スーパーオキドサイドアニオン / エンドゼリン-I / スーパーオキシドジムムターゼ / スーパーオキシドアニオン / ブロスタノイド / コレスチラミン / Mn-SOD / mRNA / superoxide dismutase / prostanoid / 一酸化窒素 / α受容体 / フルクトース / 血圧 / nitric oxide / アディポサイトカイン / NAD(P)Hoxidase / インスリン抵抗性 / adipocytokine / NAD / Hoxidase / NAD(P) oxidase / アディポネクチン / スーパーオキシド / アデポィネクチン / thromoxane A2 / 合併症 / NAD(P)H oxidase / PPARγ / スーパーオキサイド / NAD(P) H oxidase / adiponectin … More Except Principal Investigator 糖尿病 / 血管内皮細胞 / 遺伝子発現 / タンジン / タクラン / シロネ / リトスペルミン酸誘導体 / 平滑筋弛緩 / 血管弛緩物質 / 丹参 / リゾスペルミン酸誘導体 / シネロ / リソスペルミン酸誘導体 / Salvia miltiorrhiza / Lycopus Incidus / Lithospermic acid derivative / Smooth muscle relaxation / Vasodilator Less

糖尿病合併症におけるAGE,apelin,ET-1の相互作用に関する研究Principal Investigator
- Principal Investigator
  
  鎌田勝雄
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
Crosstalk of endothelin-1 and adipokine in diabetic complicationsPrincipal Investigator
- Principal Investigator
  
  KAMATA Katsuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hoshi University
糖尿病性血管合併症に関与する内皮細胞の遺伝子発現の変化の検討
- Principal Investigator
  
  KOBAYASHI Tsuneo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hoshi University
Adipocytokine-related genes and insulin resistancePrincipal Investigator
- Principal Investigator
  
  KAMATA Katsuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hoshi University
Relationship between blood lipid and endothelin-1 in the diabetic ratsPrincipal Investigator
- Principal Investigator
  
  KAMATA Katsuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hoshi University
Involvement of LDL cholestetol in the diabetes-induced cascular dysfunction)Principal Investigator
- Principal Investigator
  
  KAMATA Katsuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hosei University
新しい血管内皮細胞由来弛緩因子の基本的性質Principal Investigator
- Principal Investigator
  
  鎌田勝雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hoshi University
糖尿病性血管障害と血中LDLとの相関に関する研究Principal Investigator
- Principal Investigator
  
  鎌田勝雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Hoshi University
Effects of Chemical Components Obtained from Plants on the Aorta with Endothelium
- Principal Investigator
  
  NAGAI Masahiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Hoshi University
alpha_1遮断薬による糖尿病性血管内皮細胞障害の改善効果Principal Investigator
- Principal Investigator
  
  鎌田勝雄
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Hoshi University

All 2011 2010 2009 2007 2006

All Journal Article Presentation

[Journal Article] Mechanisms underlying the losartan treatment-induced improvement in the endothelial dysfunction seen in mesenteric arteries from type 2 diabetic rats.2010
- Author(s)
  Matsumoto T, Ishida K, Nakayama N, Taguchi K, Kobayashi T, Kamata K.
- Journal Title
  
  Pharmacol Res.
  
  Volume: 62 Pages: 271-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Gender differences in vascular reactivity of aortas from Streptozotocin-induced diabetic mice.2010
- Author(s)
  Takenouchi Y, Kobayashi K, Taguchi K, Matsumoto T, Kamata K
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 33 Pages: 1692-1697
- NAID
  130000402363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Losartan normalizes endothelium-derived hyperpolarizing factor-mediated relaxation by activating Ca2+-activated K+ channels in mesenteric artery from type 2 diabetic GK rat.2010
- Author(s)
  Matsumoto T, Ishida K, Taguchi K, Kobayashi T, Kamata K.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 112 Pages: 299-309
- NAID
  10027744374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Enhancement of mesenteric artery contraction to 5-HT depends on Rho kinase and Src kinase pathways in the ob/ob mouse model of type 2 diabetes.2010
- Author(s)
  Matsumoto T, Kobayashi T, Ishida K, Taguchi K, Kamata K.
- Journal Title
  
  Br J Pharmacol
  
  Volume: 160 Pages: 1092-1104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Vasodilator effect of Cassiarin A, a novel antiplasmodial alkaloid from Cassia siamea, in rat isolated mesenteric artery.2010
- Author(s)
  Matsumoto T, Kobayashi T, Ishida K, Hirasawa Y, Morita H, Honda T, Kamata K.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 33 Pages: 844-888
- NAID
  130000248046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Short-term angiotensin-1 receptor antagonism in type 2 diabetic Goto-Kakizaki rats normalizes endothelin-1-induced mesenteric artery contraction2010
- Author(s)
  Matsumoto T, Ishida K, Taguchi K, Kobayashi T, Kamata K.
- Journal Title
  
  Peptides.
  
  Volume: 31 Pages: 609-617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Relationship among superoxide-related enzyme, PPARs, and endothelium-dependent relaxation in murine aortas previously organ-cultured in high-glucose conditions.2010
- Author(s)
  Takenouchi Y, Kobayashi K, Taguchi K, Matsumoto T, Kamata K.
- Journal Title
  
  Can J Physiol Pharmacol.
  
  Volume: 88 Pages: 760-769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Eicosapentaenoic acid improves imbalance between vasodilator and vasoconstrictor actions of endothelium-derived factors in mesenteric arteries from rats at chronic stage of type 2 diabetes.2009
- Author(s)
  Matsumoto T, Nakayama N, Ishida K, Kobayashi T, Kamata K.
- Journal Title
  
  J Pharmacol Exp Ther. 329
  
  Pages: 324-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Pyrrolidine dithiocarbamate reduces vascular prostanoid-induced responses in aged type 2 diabetic rat model.2009
- Author(s)
  Matsumoto T, Ishida K, Kobayashi T, Kamata K.
- Journal Title
  
  J Pharmacol Sci. 110
  
  Pages: 326-333
- NAID
  10025737700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Abnormalities of endothelium-dependent responses in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats are improved by chronic treatment with thromboxane A2 synthase inhibitor.2009
- Author(s)
  Matsumoto T, Takaoka E, Ishida K, Nakayama N, Noguchi E, Kobayashi T, Kamata K.
- Journal Title
  
  Atherosclerosis. 205
  
  Pages: 87-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Activation of the PDK-1/Akt/eNOS pathway involved in aortic endothelial function differs between hyperinsulinemic and insulin-deficient diabetic rats2009
- Author(s)
  Kobayashi T, Taguchi K, Nemoto S, Nogami T, Matsumoto T, Kamata K.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Mechanisms underlying enhanced vasorelaxant response to protease-activated receptor 2-activating peptide in type 2 diabetic Goto-Kakizaki rat mesenteric artery.2009
- Author(s)
  Matsumoto T, Ishida K, Taguchi K, Kobayashi T, Kamata K.
- Journal Title
  
  Peptides. 30
  
  Pages: 1729-1734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Gender differences in age-related endothelial function in the murine aorta.2009
- Author(s)
  Takenouchi Y, Kobayashi T, Matsumoto T, Kamata K.
- Journal Title
  
  Atherosclerosis. 206
  
  Pages: 397-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Involvement of NO and MEK/ERK pathway in enhancement of endothelin-l-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat.2009
- Author(s)
  Matsumoto T, Ishida K, Nakayama N, Kobayashi T, Kamata K
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Chronic treatment with losartan (angiotensin II type 1 receptor antagonist) normalizes enhanced acetylcholine-induced coronary vasoconstriction in isolated perfused hearts of type 2 diabetic OLETF rats.2009
- Author(s)
  Matsumoto T, Ozawa Y, Taguchi K, Kobayashi T, Kamata K.
- Journal Title
  
  J Smooth Muscle Res. 45
  
  Pages: 197-208
- NAID
  10025993784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Gender differences in endothelial function in aortas from type 2 diabetic model mice.2009
- Author(s)
  Takenouchi Y, Kobayashi T, Taguchi K, Matsumoto T, Kamata K.
- Journal Title
  
  J Pharmacol Sci. 111
  
  Pages: 91-99
- NAID
  10025738765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Effect of N-epsilon-(carboxymethyl)lysine on coronary vasoconstriction in isolated perfused hearts from control and streptozotocin-induced diabetic rats.2009
- Author(s)
  Kamata K, Ozawa Y, Kobayashi T, Matsumoto T.
- Journal Title
  
  J Smooth Muscle Res. 45
  
  Pages: 125-137
- NAID
  10025298977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590105
[Journal Article] Vascular NAD(P)H oxidase mediates endothelial dysfunction in basilar arteries from Otsuka Long-Evans Tokushima Fatty(OLETF) rats2007
- Author(s)
  Matsumoto T, Kobayashi T, Wachi H, Seyama Y, Kamata K.
- Journal Title
  
  Atherosclerosis. 192(1)
  
  Pages: 15-24
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Adiponectin gene therapy of streptozotocin-induced diabetic mice using hydrodynamic injection2007
- Author(s)
  Fukushima M, Hattori Y, Tsukada H, Koga K, Kajiwara E, Kawano K, Kobayashi T, Kamata K, Maitani Y.
- Journal Title
  
  J Gene Med. 9(11)
  
  Pages: 976-985
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Imbalance between endothelium-derived relaxing and contractiong factors in mesenteric arteries from aged OLETF rats, a model of Type 2 diabetes.2007
- Author(s)
  Matsumoto T, Kakami M, Noguchi E, Kobayashi T, Kamata K.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 293(3)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Insulin-induced impairment via peroxynitrie production of endothelium-dependent relaxation and sarco/endoplasmic reticulum. Ca(2+)-ATPase function in aortad from diabetic rats.2007
- Author(s)
  Kobayashi T, Taguchi K, Takenouchi Y, Matsumoto T, Kamata K.
- Journal Title
  
  Free Radic Biol Med. 43(3)
  
  Pages: 431-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Adiponectin gene therapy of streptozotocin-induced diabetic mice using hydrodynamic injection.2007
- Author(s)
  Fukushima M, Hattori Y, Tsukada H, Koga K, Kajiwara E, Kawano K, Kobayashi T, Kamata K, Maitani Y.
- Journal Title
  
  J Gene Med. 9(11)
  
  Pages: 976-85
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Insulin-induced impairment via peroxynitrite production of endothelium-dependent relaxation and sarco/endoplasmic reticulum Ca(2+)-ATPase function in aortas from diabetic rats2007
- Author(s)
  Kobayashi T, Taguchi K, Takenouchi Y, Matsumoto T, Kamata K.
- Journal Title
  
  Free Radic Biol Med. 43(3)
  
  Pages: 431-443
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Enalapril improves impairment of SERCA-derived relaxation and enhancement of tyrosine nitration in diabetic rat aorta2007
- Author(s)
  Taguchi K, Kobayashi T, Hayashi Y, Matsumoto T, Kamata K.
- Journal Title
  
  Eur J Pharmacol. 556(1-3)
  
  Pages: 121-128
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Enalapril improves inpairment of SERCA-derived relaxation and enhancement of tyrosine nitration in diabetic rat aorta.2007
- Author(s)
  Taguchi K, Kobayashi T, Hayashi Y, Matsumoto T, Kamata K.
- Journal Title
  
  Eur J Pharmacol. 556(1-3)
  
  Pages: 121-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Mechanisms underlying the chronic pioglitazone treatment-induced improvement in the impaired endothelium-dependent relaxation seen in aortas from diabetic rats2007
- Author(s)
  Matsumoto T, Noguchi E, Kobayashi T, Kamata K.
- Journal Title
  
  Free Radic Biol Med. 42(7)
  
  Pages: 993-1007
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Imbalance between endothelium-derived relaxing and contracting factors in mesenteric arteries from aged OLETF rats,a model of Type 2 diabetes2007
- Author(s)
  Matsumoto T, Kakami M, Noguchi E, Kobayashi T, Kamata K.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 293(3)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Mechanisms underlying the chronic pioglitazone treatment-induced inprovement in the impaired endothelium-dependent relaxation seen in aortas from diabetic rats.2007
- Author(s)
  Matsumoto T, Noguchi E, Kobayashi T, Kamata K.
- Journal Title
  
  Free Radic Biol Med. 42(7)
  
  Pages: 993-1007
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Vascular NAD(P) H oxidase mediates endothelial dysfunction in basilar arteries from Otsuka Long-Evans Tokushima Fatty(OLETF) rats.2007
- Author(s)
  Matsumoto T, Kobayashi T, Wachi H, Seyama Y, Kamata K.
- Journal Title
  
  Atherosclerosis. 192(1)
  
  Pages: 15-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Mechanisms underlying the impaired EDHF-type relaxation response in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty(OLETF) rats2006
- Author(s)
  Matsumoto, T., Kobayashi, T. And Kamata, K
- Journal Title
  
  Eur.J.Pharmacol 538
  
  Pages: 132-140
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] ANG II enhances contractile responses via PI3-kinase p110 delta pathway in aortas from diabetic rats with systemic hyperinsulinemia.2006
- Author(s)
  Kobayashi T, Hayashi Y, Taguchi K, Matsumoto T, Kamata K.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 291(2)
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Vascular NAD(P)H oxidase mediates endothelial dysfunction in basilar arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats.2006
- Author(s)
  Matsumoto T, Kobayashi T, Wachi H, Seyama Y, Kamata K.
- Journal Title
  
  Atherosclerosis 192(1)
  
  Pages: 15-24
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Enhancement of methoxamine-induced contractile responses of rat ventricular muscle in streptozotocin-induced diabetes is associated with alpha1A adrenoceptor upregulation.2006
- Author(s)
  Kamata K, Satoh T, Matsumoto T, Noguchi E, Taguchi K, Kobayashi T, Tanaka H, Shigenobu K.
- Journal Title
  
  Acta Physiol(Oxf). 188(3-4)
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Mechanisms underlying the impaired EDHF-type relaxation response in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats.2006
- Author(s)
  Matsumoto T, Kobayashi T, Kamata K.
- Journal Title
  
  Eur J Pharmacol 538(1-3)
  
  Pages: 132-140
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] ANG II enhances contractile responses via PI3-kinase p110 delta pathway in aortas from diabetic rats with systemic byperinsulinemia.2006
- Author(s)
  Kobayashi, T., Hayashi, Y., Taguchi, K., Matsumoto, T., Kamata, K.
- Journal Title
  
  Am. J. Physiol. Heart Circ. Physiol 291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Apocynin normalizes hyperreactivity to phenylephrine in mesenteric arteries from cholesterol-fed mice by improving endothelium-derived hyperpolarizing factor response.2006
- Author(s)
  Matsumoto, T., Miyamori, K., Kobayashi, T., Kamata, K.
- Journal Title
  
  Free Radic. Biol. Med 41
  
  Pages: 1289-1303
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Effects of anthocyanidin derivative (HK-008) on relaxation in rat perfused mesenterial bed2006
- Author(s)
  Kamata, K., Makino, A., Kanie, N., Oda, S., Matsumoto, T., Kobayashi, T., Kikuchi, T., Nishimura, M. And Honda, T
- Journal Title
  
  J.Smooth Muscle Res 42
  
  Pages: 75-88
- NAID
  110004833362
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Mechanisms underlying lysophosphatidylcholine-induced potentiation of vascular contractions in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat aorta.2006
- Author(s)
  Matsumoto T, Kobayashi T, Kamata K.
- Journal Title
  
  Br J Pharmacol. 149(7)
  
  Pages: 931-941
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Changes in aortic endothelial gene expressions and relaxation responses following chronic short-term insulin treatment in diabetic rats2006
- Author(s)
  Kobayashi, T., Oishi, K., Hayashi, Y., Matsumoto, T. And Kamata, K.
- Journal Title
  
  Atherosclerosis 185
  
  Pages: 47-57
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Specific impairment of endothelium-derived hyperpolarizing factor-type relaxation in meseateric arteries from streptozotocin-induced diabetic mice2006
- Author(s)
  Matsumoto, T., Miyamori, K., Kobayashi, T. And Kamata, K
- Journal Title
  
  Vascul, Pharmacol 44
  
  Pages: 450-460
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Specific impairment of endothelium-derived hyperpolarizing factor-type relaxation in mesenteric arteries from streptozotocin-induced diabetic mice.2006
- Author(s)
  Matsumoto, T., Miyamori, K., Kobayashi, T., Kamata, K.
- Journal Title
  
  Vascul, Pharmacol 44
  
  Pages: 450-460
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Mechanisms underlying the impaired EDHF-type relaxation response in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty(OLETF) rats.2006
- Author(s)
  Matsumoto, T., Kobayashi, T., Kamata, K.
- Journal Title
  
  Enr. J. Pharmacol 538
  
  Pages: 132-140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Apocynin normalizes hyperreactivity to phenylephrine in mesenteric arteries from cholesterol-fed mice by improving endothelium-derived hyperpolarizing factor response.2006
- Author(s)
  Matsumoto T, Miyamori K, Kobayashi T, Kamata K.
- Journal Title
  
  Free Radic Biol Med. 41(8)
  
  Pages: 1289-1303
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] ANG II enhances contractile responses via PI3-kinase p110 delta pathway in aortas from diabetic rats with syetemic hyperinsulinemia2006
- Author(s)
  Kobayashi, T., Hayashi, Y., Taguchi, K., Matsumoto, T. And Kamata, K.
- Journal Title
  
  Am.J.Physiol.Heart Circ.Physiol 291
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Effects of anthocyanidin derivative(HK-008) on relaxation in rat perfused mesenterial bed.2006
- Author(s)
  Kamata, K., Makino, A., Kanie, N., Oda, S., Matsumoto, T., Kobayashi, T., Kikuchi, T., Nishimura, M., Honda, T.
- Journal Title
  
  J. Smooth Muscle Res 42
  
  Pages: 75-88
- NAID
  110004833362
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Enhancement of methoxamine-induced contractile responses of rat ventricular muscle in streptozotocin-induced diabetes is associated with alphalA adrenoceptor upregulation2006
- Author(s)
  Kamata, K., Satoh, T., Matsumoto, T., Nogucbi, E., Taguchi, K., Kobayashi, T., Tanaka, H. And Shigenobu, K.
- Journal Title
  
  Acta.Physiol (Oxf) 188
  
  Pages: 173-183
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Changes in aortic endothelial gene expressions and relaxation responses following chronic short-term insulin treatment in diabetic rats.2006
- Author(s)
  Kobayashi, T., Oishi, K., Hayashi, Y., Matsumoto, T., Kamata, K.
- Journal Title
  
  Atherosclerosis 185
  
  Pages: 47-57
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Journal Article] Enhancement of methoxamine-induced contractile responese of rat ventricular muscle in streptozotocin-induced diabetes is associated with alphalA adrenoceptor upregulation.2006
- Author(s)
  Kamata, K., Satoh, T., Matsumoto, T., Noguchi, E., Taguchi, K., Kobayashi, T., Tanaka, H., Shigenobu, K.
- Journal Title
  
  Acta. Physiol(Oxf) 188
  
  Pages: 173-183
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590245
[Presentation] 2型糖尿病時における血管内皮機能障害にはGRK2増加が関与する2011
- Author(s)
  田口久美子、小林恒雄、松本貴之、鎌田勝雄
- Organizer
  第40回日本心脈管作動物質学会
- Place of Presentation
  かがわ国際会議場
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病時におけるAkt/NOS経路を介した血管弛緩反応の減弱はPKC/GRK2活性が関与する2011
- Author(s)
  守重昭孝、田口久美子、小林恒雄、松本貴之、鎌田勝雄
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上発表)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病モデル胸部大動脈におけるエンドセリン-1収縮の増大と糖化最終産物の影響2011
- Author(s)
  根本真吾、小林恒雄、田口久美子、松本貴之、鎌田勝雄
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上発表)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 糖尿病ラット胸部大動脈におけるCaMKIIとプロテインホスファターゼの活性2011
- Author(s)
  阿部佑基、小林恒雄、根本真吾、田口久美子、松本貴之、鎌田勝雄
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上発表)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病時における血管内皮機能障害にはGRK2増加が関与する2011
- Author(s)
  田口久美子、小林恒雄、松本貴之、鎌田勝雄
- Organizer
  日本薬学会第131年会
- Place of Presentation
  (誌上発表)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 日本人の体質に合った糖尿病治療を考える2011
- Author(s)
  鎌田勝雄
- Organizer
  日本薬学会近畿支部市民公開講座
- Place of Presentation
  薬業年金会館
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病時におけるP2Y receptorを介した血管収縮反応性増大に対するlosartanの効果2011
- Author(s)
  石田恵子、松本貴之、田口久美子、小林恒雄、鎌田勝雄
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上発表)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 糖尿病性細小血管障害におけるcyclic-AMPの関与2010
- Author(s)
  鎌田勝雄
- Organizer
  第36回中国地区MMC研究会
- Place of Presentation
  ホテルグランヴィア広島
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] Altered ATP- and UTP-induced contractions in superior mesenteric artery from type 2 diabetic Goto-Kakizaki rats : Effect of angiotensin II type-1 receptor antagonism2010
- Author(s)
  Takayuki Matsumoto, Keiko Ishida, Kumiko Taguchi, Tsuneo Kobayashi, Katsuo Kamata.
- Organizer
  High Blood Pressure Research 2010 Scientific Sessions
- Place of Presentation
  Omni Shoreham Hotel (Washington DC, USA)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病時の血管機能障害に対するCa^<2+>依存性およびCa^<2+>非依存性経路の影響と新規キナーゼの関与2010
- Author(s)
  根本真吾、小林恒雄、田口久美子、松本貴之、鎌田勝雄
- Organizer
  第122回日本薬理学会関東部会
- Place of Presentation
  静岡県立大学
- Year and Date
  2010-06-05
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病モデル腸間膜動脈におけるRho kinase pathwayの5-HT収縮増強に対する影響2010
- Author(s)
  石田恵子、松本貴之、田口久美子、小林恒雄、鎌田勝雄
- Organizer
  Pharmaco-Hematology Symposium
- Place of Presentation
  日本薬学会長井記念ホール
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病モデル胸部大動脈におけるインスリンシグナルとSrc/Pyk2/PDK1/Akt経路の関与2010
- Author(s)
  根本真吾、小林恒雄、田口久美子、松本貴之、鎌田勝雄
- Organizer
  第52回日本平滑筋学会総会
- Place of Presentation
  仙台市産業プラザ(アエル)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] Losartan normalizes P2Y-receptor-mediated contraction by suppression of cPLA_2/COX pathway in superior mesenteric arteries type 2 diabetic Goto Kakizaki rats.2010
- Author(s)
  Takayuki Matsumoto, Keiko Ishida, Kumiko Taguchi, Tsuneo Kobayashi, Katsuo Kamata.
- Organizer
  Southern Translational Education And Research Conference (STAR)
- Place of Presentation
  Augusta Marriott Hotel (Augusta, GA, USA)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] STZ誘発性1型糖尿病ラットにおけるCaMKIIとプロテインホスファターゼの活性2010
- Author(s)
  阿部佑基、小林恒雄、根本真吾、田口久美子、松本貴之、鎌田勝雄
- Organizer
  第123回日本薬理学会関東部会
- Place of Presentation
  自治医科大学地域医療情報研修センター
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病時におけるGRK2を介したAkt/eNOS経路の抑制と血管弛緩反応の減弱2010
- Author(s)
  田口久美子、小林恒雄、松本貴之、鎌田勝雄
- Organizer
  第52回日本平滑筋学会総会
- Place of Presentation
  仙台市産業プラザ(アエル)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 糖尿病時におけるP2Y-receptorを介した血管収縮反応増大に対するlosartanの効果2010
- Author(s)
  石田恵子、松本貴之、田口久美子、小林恒雄、鎌田勝雄
- Organizer
  第40回日本心脈管作動物質学会
- Place of Presentation
  かがわ国際会議場
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病マウス腸間膜病脈における5-HT収縮増強とRho kinase, Src kinase pathwayとの関係2010
- Author(s)
  石田恵子、松本貴之、田口久美子、小林恒雄、鎌田勝雄
- Organizer
  第52回日本平滑筋学会総会
- Place of Presentation
  仙台市産業プラザ(アエル)
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 糖尿病と血管内皮機能2010
- Author(s)
  小林恒雄、根本真吾、田口久美子、鎌田勝雄
- Organizer
  生体機能と創薬シンポジウム2010京都
- Place of Presentation
  ホテルグランビア京都
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病モデル胸部大動脈における内皮依存性弛緩反応の減弱とCaMKII活性の影響について2009
- Author(s)
  小林恒雄、根本真吾、松本貴之、鎌田勝雄
- Organizer
  第51回日本平滑筋学会総会
- Place of Presentation
  名古屋市立大学病院ホール
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] Metformin improves imbalance between vasodilator and vasoconstrictor actions of endothelium-derived factors in mesenteric arteries from type 2 diabetic rats.2009
- Author(s)
  Matsumoto, T., Kobayashi, T., Kamata, K.
- Organizer
  10^<th> International Symposium on Mechanisms of Vasodilation
- Place of Presentation
  Matsushima, Miyagi, Japan
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] Metformin normalizes imbalance between endothelium-derived factors in mesenteric arteries from type 2 diabetic rats.2009
- Author(s)
  Ishida, K., Matsumoto, T., Kobayashi, T., Kamata, K.
- Organizer
  2^<nd> Joint Symposium on Future Prospect of Pharmaceutical Sciences
- Place of Presentation
  星薬科大学
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] Streptozotocin誘発糖尿病ラット摘出心臓潅流標本を用いた冠動脈収縮反応の検討2009
- Author(s)
  小澤遊太、松本貴之、田口久美子、小林恒雄、鎌田勝雄
- Organizer
  第3回先端分子薬理学研究会
- Place of Presentation
  慶応義塾大学薬学部
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病ラット腸間膜動脈の内皮機能障害に対するシロスタゾール慢性投与の影響2009
- Author(s)
  中山直亮、松本貴之、石田恵子、田口久美子、小林恒雄、鎌田勝雄
- Organizer
  第120回日本薬理学会関東部会
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病モデル動物におけるProtease-activated receptor 2-activating peptide (PAR2-AP)弛緩増強のメカニズム2009
- Author(s)
  石田恵子、松本貴之、田口久美子、小林恒雄、鎌田勝雄
- Organizer
  第121回日本薬理学会関東部会
- Place of Presentation
  東京女子医科大学
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 2型糖尿病ラット腸間膜動脈のendothelin-1収縮増強にはNOとMEK/ERK pathwayが関与する2009
- Author(s)
  松本貴之、石田恵子、小林恒雄、鎌田勝雄
- Organizer
  第51回日本平滑筋学会総会
- Place of Presentation
  名古屋市立大学病院ホール
- Data Source
  KAKENHI-PROJECT-21590105
[Presentation] 蘇木成分の血管弛緩作用について2009
- Author(s)
  鈴木万恵美、佐々木陽平、南雲清二、細川友和、松本貴之、小林恒雄、鎌田勝雄
- Organizer
  日本生薬学会第56回年会
- Place of Presentation
  京都薬科大学(愛学館)
- Data Source
  KAKENHI-PROJECT-21590105

1. SUENAGA Hiroshi (70277698)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. KOBAYASHI Tsuneo (90339523)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAGAI Masahiro (30090666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAGUMO Seiji (80097162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NOGUCHI Mariko (80247121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUMOTO Takayuki (30366835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAMATA Katsuo 鎌田 勝雄

Research Projects

Research Products

Co-Researchers

糖尿病合併症におけるAGE,apelin,ET-1の相互作用に関する研究Principal Investigator

Principal Investigator

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Crosstalk of endothelin-1 and adipokine in diabetic complicationsPrincipal Investigator

Principal Investigator

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糖尿病性血管合併症に関与する内皮細胞の遺伝子発現の変化の検討

Principal Investigator

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Adipocytokine-related genes and insulin resistancePrincipal Investigator

Principal Investigator

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Relationship between blood lipid and endothelin-1 in the diabetic ratsPrincipal Investigator

Principal Investigator

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Involvement of LDL cholestetol in the diabetes-induced cascular dysfunction)Principal Investigator

Principal Investigator

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新しい血管内皮細胞由来弛緩因子の基本的性質Principal Investigator

Principal Investigator

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糖尿病性血管障害と血中LDLとの相関に関する研究Principal Investigator

Principal Investigator

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Effects of Chemical Components Obtained from Plants on the Aorta with Endothelium

Principal Investigator

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alpha_1遮断薬による糖尿病性血管内皮細胞障害の改善効果Principal Investigator

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[Journal Article] Mechanisms underlying the losartan treatment-induced improvement in the endothelial dysfunction seen in mesenteric arteries from type 2 diabetic rats.2010

Author(s)

Journal Title

Data Source

[Journal Article] Gender differences in vascular reactivity of aortas from Streptozotocin-induced diabetic mice.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Losartan normalizes endothelium-derived hyperpolarizing factor-mediated relaxation by activating Ca2+-activated K+ channels in mesenteric artery from type 2 diabetic GK rat.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Enhancement of mesenteric artery contraction to 5-HT depends on Rho kinase and Src kinase pathways in the ob/ob mouse model of type 2 diabetes.2010

Author(s)

KAMATA Katsuo 鎌田勝雄