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KUNITOMO Masaru  国友 勝

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国友 勝  クニトモ マサル

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Researcher Number 40125133
Other IDs
External Links
Affiliation (based on the past Project Information) *help 1999 – 2006: 武庫川女子大学, 薬学部, 教授
1995 – 1997: 武庫川女子大学, 薬学部, 教授
Review Section/Research Field
Principal Investigator
医薬分子機能学 / Environmental pharmacy
Keywords
Principal Investigator
ATP / 3-Nitrotyrosine / Peroxynitrite / 8-OHdG / Calcium ion / 低浸透圧 / 培養内皮細胞 / カルシウムイオン / プリン受容体 / ラット尾動脈 … More / Oxidized LDL / Peroxynitrite-like reactants / Oxidative stress / Atherosclerosis / Cigarette smoking / マトリゲル / 肺胞膜 / ラット / 肺胞壁 / 3-Nitorotyrosine / たばこ煙水抽出液 / アポE欠損マウス / 3-nitrotyrosine / 酸化LDL / peroxynitrite類似反応物質 / peroxynitrite / 酸化ストレス / 動脈硬化 / 喫煙 / Cell volume / permeability / purine receptor / rat erythrocytes / cultured endothelial cells / ラット尾動脈内皮細胞 / ギャップジャンクション / 細胞形態調節機構 / 細胞容積調節機構 / 血管透過性 / ラット赤血球 / Regulatory cell volume / hypotonicity / cultured endothelial cell / Mechanical stimulation / Rat caudal artery / 細胞体積膨張 / 細胞容積調節 / 機械的刺激 / 局所循環調節 / 内皮細胞 / プリン物質 / ニトロアルギニン / 一酸化窒素 / ノルアドレナリン / 機械的(伸展)刺激 / Shear Stress / 抑制性神経伝達調節 / シナプス前プリン受容体 / 交感神経 / 血圧 / 自然発症高血圧ラット / α_1アドレナリン受容体 / 血管内皮細胞 Less
  • Research Projects

    (5 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (2 People)
  •  Elucidation of mechanisms that cigarette smoking causes vascular wall injury through oxidative stressPrincipal Investigator

    • Principal Investigator
      KUNITOMO Masaru
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Mukogawa Women's University
  •  Cross talk interaction between vascular endothelial cells and blood cells via ATPPrincipal Investigator

    • Principal Investigator
      KUNITOMO Masaru
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Mukogawa Women's University
  •  Mechanisms of ATP-release induced by mechanical stimulation and it's physiological roles.Principal Investigator

    • Principal Investigator
      KUNITOMO Masaru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Mukogawa Women's University
  •  局所循環調節におけるShear Stressと内皮由来ATPの生理的役割Principal Investigator

    • Principal Investigator
      国友 勝
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Mukogawa Women's University
  •  高血圧の発症・維持における血管内皮由来ATPの生理的、病態生理的意義に関する研究Principal Investigator

    • Principal Investigator
      国友 勝
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Mukogawa Women's University

All 2007 2006 2005

All Journal Article Book

  • [Book] Mechanisms for oxidative modification of LDL by cigarette smoking : New insight into potential implications for atherosclerosis. In "Current Developments in Atherosclerosis Research" (edited by Misra Schoenhagen)2006

    • Author(s)
      Yamaguchi Y, Haginaka J, Kunitomo M
    • Publisher
      Nova Science Publisher, Inc.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Oxidants in the gas phase of cigarette smoke pass through the lung alveolar wall and raise systemic oxidative stress2007

    • Author(s)
      Yamaguchi Y, Kunitomo M et al.
    • Journal Title

      J.Pharmacol.Sci 103 (in press)

    • NAID

      10024312939

    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Impaired effect of salt loading on nitric oxide-mediated relaxation in aortas from stroke-prone spontaneously hypertensive rats2007

    • Author(s)
      Kagota S, Kunitomo M et al.
    • Journal Title

      Clinical and Experimental Pharmacology and Physiology 34(1-2)

      Pages: 48-54

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Impaired effect of salt loading on nitric oxide-mediated relaxation in aortas from stroke-prone spontaneously hypertensive rats.2007

    • Author(s)
      Kagota S, Kubota Y, Nejime N, Nakamura K, Kunitomo M, Shinozuka K.
    • Journal Title

      Clinical and Experimental Pharmacology and Physiology 34

      Pages: 48-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Impaired effect of salt loading on nitric oxide-mediated relaxation in aortas from stroke-prone spontaneously hypertensive rats2007

    • Author(s)
      Kagota S, Kunitomo M et al.
    • Journal Title

      Clin.Exp.Pharmcol.Physiol. 34

      Pages: 48-54

    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Oxidants in the gas phase of cigarette smoke pass through the lung alveolar wall and raise systemic oxidative stress.2007

    • Author(s)
      Yamaguchi Y, Nasu F, Harada A, Kunitomo M.
    • Journal Title

      Journal of Pharmacological Sciences 103

      Pages: 275-82

    • NAID

      10024312939

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Oxidants in the gas phase of cigarette smoke pass through the lung alveolar wall and raise systemic oxidative stress2007

    • Author(s)
      Yamaguchi Y, Kunitomo M et al.
    • Journal Title

      Journal of Pharmacological Sciences 103(3)

      Pages: 275-282

    • NAID

      10024312939

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome2006

    • Author(s)
      Yamaguchi Y, Kunitomo M et al.
    • Journal Title

      Life Sci 79

      Pages: 2474-2479

    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Mechanisms for oxidative modification of LDL by cigarette smoking : New insight into potential implications for atherosclerosis.2006

    • Author(s)
      Yamaguchi Y, Haginaka J, Kunitomo M.
    • Journal Title

      In "Current Developments in Atherosclerosis Research" edited by Misra Schoenhagen (Nova Science Publlsher.Inc.) pp. 87-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Disturbances in nitric oxide/cyclic guanosine monophosphate system in SHR/NDmcr-cp rats, a model of metabolic syndrome2006

    • Author(s)
      Kagota S, Kunitomo M et al.
    • Journal Title

      Life Sciences 78(11)

      Pages: 1187-1196

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome2006

    • Author(s)
      Yamaguchi Y, Kunitomo M et al.
    • Journal Title

      Nitric Oxide 15

      Pages: 380-386

    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Disturbances in nitric oxide/cyclic guanosine monophosphate system in SHR/NDmcr-cp rats, a model of metabolic syndrome.2006

    • Author(s)
      Kagota S, Yamaguchi Y, Tanaka N, Kubota Y, Kobayashi K, Nejime N, Nakamura K, Kunitomo M, Shinozuka K.
    • Journal Title

      Life Sciences 78

      Pages: 1187-96

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome2006

    • Author(s)
      Yamaguchi Y, Kunitomo M et al.
    • Journal Title

      Nitric Oxide 15(4)

      Pages: 380-386

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome.2006

    • Author(s)
      Yamaguchi Y, Yoshikawa N, Kagota S, Nakamura K, Haginaka J. Kunitomo M.
    • Journal Title

      Nitric Oxide 15

      Pages: 380-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome2006

    • Author(s)
      Yamaguchi Y, Kunitomo M et al.
    • Journal Title

      Life Sciences 79(26)

      Pages: 2474-2479

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome.2006

    • Author(s)
      Yamaguchi Y, Yamada K, Yoshikawa N, Nakamura K, Haginaka J, Kunitomo M.
    • Journal Title

      Life Sciences 79

      Pages: 2474-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Facilitated nitration and oxidation of LDL in cigarette smokers.2005

    • Author(s)
      Yamaguchi Y, Haginaka J, Morimoto S, Fujioka Y, Kunitomo M.
    • Journal Title

      European Journal Clinical Investigation 35

      Pages: 186-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • [Journal Article] Facilitated nitration and oxidation of LDL in cigarette smokers.2005

    • Author(s)
      Yamaguchi Y, Kunitomo M et al.
    • Journal Title

      European Journal Clinical Investigation 35(3)

      Pages: 186-193

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590100
  • 1.  SHINOZUKA Kazumasa (50117777)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  YAMAGUCHI Yu (90183681)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results

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