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Sugiura Tsutomu  杉浦 勉

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SUGIURA Tsutomu  杉浦 勉

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Researcher Number 40131924
Other IDs
Affiliation (Current) 2025: 産業医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help 2013: 産業医科大学, 医学部, 非常勤講師
2012 – 2013: 産業医科大学, 医学部, 研究員
2010 – 2011: 産業医科大学, 産業医学研究支援施設, 准教授
2008 – 2009: 産業医科大学, 医学部, 講師
2003 – 2004: 産業医科大学, 医学部, 講師
2000 – 2001: 産業医科大学, 医学部, 講師
1986: Dept. of Immunol., Schl. of Med., Univ. of OEH., Assistant, 医学部, 助手
Review Section/Research Field
Principal Investigator
Children studies (Studies of environment on children)
Except Principal Investigator
Immunology / Immunology / Emergency medicine
Keywords
Principal Investigator
Treg / 樹状細胞 / 次世代影響 / 胎児期曝露 / 骨髄細胞 / ホルムアルデヒド / 胸腺細胞 / 転写因子 / 胎児期暴露 / STAT5 / 骨髄由来細胞 / 制御性T細部 / 室内環境化学物質 … More
Except Principal Investigator
… More c mouse / BALB / prostaglandin / IL-12 / IFN-γ / IL-3 / PGE synthase / PLA_2 / macrophage / MDC / IFN-y / Th2 / Th1 / Cryoprecipitability / IgG3 and IgM / Human monoclonal cryoglobulins / IgM / IgG3 / 分子性状 / クリオ沈澱性 / ヒト単クローン性クリオグロブリン / arachidonic acid / IL-4 / Th1, Th2 / 免疫応答 / マクロファージ / Septic Shock / PG合成酵素ノックアウトマウス / プロスタグランジン / Septic shock Less
  • Research Projects

    (5 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (5 People)
  •  The influence on bone marrow cells of the indoor environment chemicals: Analysis of dendritic cell differentiation and the Treg inductionPrincipal Investigator

    • Principal Investigator
      SUGIURA Tsutomu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Children studies (Studies of environment on children)
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Analysis of biomarker for septic shock

    • Principal Investigator
      YAMASHITA Uki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Mechanism of enhanced production of prostaglandins in BALB/c macrophages

    • Principal Investigator
      YAMASHITA Uki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      University of Occupational and Environmental Health(UOEH)
  •  Role ofprostaglandin in the selective activation of Th2 cells in BALB/c mice

    • Principal Investigator
      YAMASHITA Uki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      University of Occupational and Environmental Health
  •  Studies on the Molecular Structure and Function of Human Monoclonal Cryoimmunoglobulins.

    • Principal Investigator
      NAKAMURA Hiroshi
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      School of Medicine, University of Occupational and Environmental Health, Japan

All 2011 2010 2009 2005 2004 2003

All Journal Article Presentation

  • [Journal Article] Stimulation of IFN-gamma production by garlic lectin in mouse spleen cells : Involvement of IL-12 via activation of p38 MAPK and ERK in macrophages.2011

    • Author(s)
      Dong Q., Sugiura T., Toyohira Y., Yoshida Y., Yanagihara N., Karasaki Y.
    • Journal Title

      Phytomedicine 18

      Pages: 309-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Stimulation of IFN-gamma production by garlic lectin in mouse spleen cells : Involvement of IL-12 via activation of p38 MAPK and ERK in macrophages.2011

    • Author(s)
      Dong, Q., Sugiura, T., Yoshida Y., et al.
    • Journal Title

      Phytomedicine

      Volume: 18 Pages: 309-316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Apoptosis induction through proteasome inhibitory activity of cucurbitacin D inhuman T-cell leukemia.2011

    • Author(s)
      Ding, N., Yamashita, U., Sugiura, T., Yoshida Y., et al.
    • Journal Title

      Cancer

      Volume: In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Apoptosis induction through proteasome inhibitory activity of cucurbitacin D in human T-cell leukemia.2011

    • Author(s)
      Ding N., Yamashita U., Matsuoka H., Sugiura T., Tsukada J., Noguchi J., Yoshida Y.
    • Journal Title

      Cancer (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Thymocytes are activated by toluene inhalation through the transcription factors NF-κB, STAT5 and NF-AT.2010

    • Author(s)
      Liu JQ., Yoshida Y., Kunugita N., Noguchi J., Sugiura T., Ding N., Arashidani K., Fujimaki H., Yamashita U.
    • Journal Title

      Journal of Applied Toxicology 30

      Pages: 656-660

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Thymocytes are activated by toluene inhalation through the transcription factors NF-κ B, STAT5 and NF-AT.2010

    • Author(s)
      Liu, JQ., Yoshida Y., Sugiura T., Yamashita U., et al.
    • Journal Title

      Journal of Applied Toxicology

      Volume: 30 Pages: 656-660

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Formaldehyde inhalation activates signal transducer and activator of transcription 5 in immune cells.2009

    • Author(s)
      Yoshida, Y., Ding, N., Liu, JQ., Noguchi, J., Sugiura, T., Kunugita, N.
    • Journal Title

      European Immunology Conference 39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Formaldehyde inhalation activates signal transducer and activator of transcription 5 in immune cells.2009

    • Author(s)
      Yoshida Y., Ding N., Liu JQ., Noguchi J., Sugiura T., Kunugita N.
    • Journal Title

      European Immunology Conference 39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Effects of 1-bromopropane, a substitute for chlorofluorocarbons2009

    • Author(s)
      Yoshida Y., Nakano Y., Ueno S., Liu JQ., Fueta Y., Ishidao T., Kunugita N., Yanagihara N., Sugiura T., Yamashita U., Hori H.
    • Journal Title

      on brain-derived neurotrophic factor (BDNF) expression Int ImmPharma 9

      Pages: 433-438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] The NF-kappaB RelA subunit confers resistance to Leishmania major by inducing nitric oxide synthase 2 and Fas expression but not Th1 differentiation.2009

    • Author(s)
      Omata S., Kuroda E., Sugiura T., Yamashita U.
    • Journal Title

      J Immunol 182

      Pages: 4910-4916

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Cucurbitacin D isolated from Trichosanthes kirilowii induces apoptosis in human hepatocellular carcinoma cells in vitro.2009

    • Author(s)
      Takahashi, N., Yoshida, Y., Sugiura, T., Masuno K., Fujino, A, Yamashita, U
    • Journal Title

      International Immunopharmacology 9

      Pages: 508-513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] The indoor air pollutant 2-ethyl-hexanol activates CD4 cells.2009

    • Author(s)
      Yoshida, Y., 劉冀琴, 杉浦勉, 石田尾徹, 上野晋, 笛田由紀子, 欅田尚樹, 保利一, 山下優毅
    • Journal Title

      Chemico-Bio Intera 177

      Pages: 137-141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Effects of 1-bromopropane, a substitute for chlorofluorocarbons, on brain-derived neurotrophic factor (BDNF) expression2009

    • Author(s)
      Yoshida, Y., Nakano, Y., Ueno, S., Liu, JQ., Fueta, Y., Ishidao, T., Kunugita, N., Yanagihara, N., Sugiura, T., Yamashita, U., Hori, H.
    • Journal Title

      Int ImmPharma 9

      Pages: 433-438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Cucurbitacin D isolated from Trichosanthes kirilowii induces apoptosis in human hepatocellular carcinoma cells in vitro.2009

    • Author(s)
      Takahashi N., Yoshida Y., Sugiura T., Matsuno K., Fujino A, Yamashita U.
    • Journal Title

      International Immunopharmacology 9

      Pages: 508-513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] An indoor air pollutant 2-ethyl-hexanol activates CD4 cells.2009

    • Author(s)
      Yoshida Y., Liu J.Q., Sugiura T., Ishidao T., Ueno S., Yanagita H., Fueta Y., Kunugita N., Hori H., Yamashita U.
    • Journal Title

      Chemico-Bio Intera 177

      Pages: 137-141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] The NF-kappaB RelA subunit confers resistance to Leishmania major by inducing nitric oxide synthase 2 and Fas expression but not Th1 differe ntiation.2009

    • Author(s)
      Omata, S., Kuroda, E., Sugiura, T., Yamashita, U.
    • Journal Title

      J Immunol 182

      Pages: 4910-4916

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Journal Article] Effect of endocrine disrupters on macrophage functions in vitro2005

    • Author(s)
      Yamashita, U., Sugiura, T., Yoshida, Y., Kuroda, E.
    • Journal Title

      Journal of UOEH 27

      Pages: 1-10

    • NAID

      110001844723

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590444
  • [Journal Article] Effect of endocrine disrupters on macrophage functions in vitro2005

    • Author(s)
      Yamashita, U., Sugiura, T., Yoshida, Y., Kuroda, E.
    • Journal Title

      J. UOEH 27

      Pages: 1-10

    • NAID

      110001844723

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590444
  • [Journal Article] Effect of endocrine disrupters on macrophage functions in vitro2005

    • Author(s)
      Yamashita, Y., Sugiura, T., Yoshida, Y., Kuroda, E.
    • Journal Title

      Journal of UOEH 27

      Pages: 1-10

    • NAID

      110001844723

    • Data Source
      KAKENHI-PROJECT-15590444
  • [Journal Article] Dysfunction of macrophages in metallothionein-knock out mice2004

    • Author(s)
      Sugiura, T., Kuroda, E., Yamashita, U.
    • Journal Title

      J. UOEH 26

      Pages: 193-205

    • NAID

      110001259685

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590444
  • [Journal Article] Dysfunction of macrophages in metallothionein-knock out mice2004

    • Author(s)
      Sugiura, T., Kuroda, E., Yamashita, U.
    • Journal Title

      Journal of UOEH 26

      Pages: 193-205

    • NAID

      110001259685

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590444
  • [Journal Article] Effect of endocrine disrupters on thymocytes in vitro2003

    • Author(s)
      Yamashita, U., Sugiura, T., Yoshida, Y., Kuroda, E.
    • Journal Title

      Journal of UOEH 25

      Pages: 161-170

    • NAID

      110001261825

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590444
  • [Journal Article] Effect of endocrine disrupters on thymocytes in vitro2003

    • Author(s)
      Yamashita, U., Sugiura, T., Yoshida, Y., Kuroda, E.
    • Journal Title

      J. UOEH 25

      Pages: 161-170

    • NAID

      110001261825

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590444
  • [Presentation] Oxidative stress and apoptotic changes in mouse macrophages exposed to cadmium.2010

    • Author(s)
      Sugiura, T., Yamashita, U.
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      神戸(神戸国際会議場)
    • Year and Date
      2010-08-25
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Presentation] Oxidative stress and apoptotic changes in mouse macrophages exposed to cadmium.2010

    • Author(s)
      Sugiura T., 山下優毅
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-08-25
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Presentation] カドミウムにより誘導される酸化傷害に対するレドックス制御におけるメタロチオネインの役割2009

    • Author(s)
      杉浦勉, 山下優毅
    • Organizer
      第39回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪(大阪国際会議場)
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-20592132
  • [Presentation] カドミウムにより誘導される酸化傷害に対するレドックス制御におけるメタロチオネインの役割2009

    • Author(s)
      杉浦勉,山下優毅
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-20592132
  • 1.  YAMASHITA Uki (00028680)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 23 results
  • 2.  YOSHIDA Yasuhiro (10309958)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 19 results
  • 3.  KURODA Etsushi (10299604)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 4.  NAKAMURA Hiroshi (60012720)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  NISHIMURA Yoshihisa (90092288)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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