KUMAI Toshio 熊井俊夫

… Alternative Names

熊井俊夫クマイトシオ

熊井秀夫クマイトシオ

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Researcher Number	40139671
Other IDs
Affiliation (Current)	2025: 聖マリアンナ医科大学, 医学研究科, 名誉教授
Affiliation (based on the past Project Information) *help	2020 – 2021: 聖マリアンナ医科大学, 医学研究科, 名誉教授 2016 – 2019: 聖マリアンナ医科大学, 医学研究科, 教授 2013 – 2015: 聖マリアンナ医科大学, 医学(系)研究科(研究院), 教授 2010: 聖マリアンナ医科大学, 医学(系)研究科(研究院), 教授 2007 – 2009: St. Marianna University School of Medicine, Department of Pharmacology, Associate Professor 2006: 聖マリアンナ医科大学, 医学部, 助教授 1991 – 1992: 聖マリアンナ医科大学, 医学部, 講師
Review Section/Research Field	Except Principal Investigator Sports science / Applied pharmacology / Obstetrics and gynecology / General surgery / General pharmacology
Keywords	Except Principal Investigator 遺伝子多型 / DPD / Steroid hormones / スポーツ心理学 / ハプロタイプ / トランスポーター / 薬物代謝酵素 / 抗癌薬 / テーラーメード医療 / 情緒 … More / 自律神経 / 感情 / ストレス反応 / 子宮頸部扁平上皮癌 / 扁平上皮癌 / 子宮頸癌 / レクチンマイクロアレイ / 腺管構造破綻 / 乳腺外科 / 予後不良 / 腺菅構造 / 管腔構造 / bioinformatics / BRCA1 / エストロゲン / 乳癌 / Haplotype / Transporter / Drug metabolizing enzymes / Gene polymorphism / Anti-cancer drugs / Tailor made therapy / prostatic carcinoma / SHR / Androben-receptor / Ventral prostate / Alkylation / Chromosome-aberration / Hypercholesterolemia / androgen receptor / 前立腺癌 / 高血圧自然発症ラット(SHR) / Androgen receptor / 前立腺前葉 / アルキル化塩基 / DNA損傷能 / 高脂血症 / スポーツ心理 / 気分評価 / ストレス / 感情不安 Less

Many-sided analysis of the psychological stress reactions in sports.
- Principal Investigator
  
  YATABE KANAKA
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Sports science
- Research Institution
  St. Marianna University School of Medicine
The effect of oestrogen with BRCA1 dysfunction on carcinogenesis
- Principal Investigator
  
  SATO KO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
Association between the Serotonin Transporter Genotypes and Japanese-specific State-Trait Anxiety under Pressure in Sports (ballet dancers for example).
- Principal Investigator
  
  YATABE KANAKA
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Sports science
- Research Institution
  St. Marianna University School of Medicine
Glycan profiling using formalin-fixed, paraffin-embedded tissues: Hippeastrum hybrid lectin is a sensitive biomarker for squamous cell carcinoma of the cervix
- Principal Investigator
  
  Tozawa-Ono Akiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  St. Marianna University School of Medicine
The Practical Use Study of Tailor made medicine : Accerelate of genotyping System and Feedback System to Primary Doctor
- Principal Investigator
  
  KOBAYASHI Shinichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  St.Marianna University School of Medicine
The Tailor Made Therapy of Anti-Cancer Drugs
- Principal Investigator
  
  KOBAYASHI Shinichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  St.Marianna University School of Medicine
Disorder of steroidogeneis and defective repair of DNA in genetic disorder of lipid metabolism by the rat
- Principal Investigator
  
  MASUBUCHI Yoshiko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  St.Marianna University School of Medicine

All 2021 2019 2018 2017 2016 2015 2014 2011 2009 2007 Other

All Journal Article Presentation

[Journal Article] Effects of Different Exercise Conditions on Antioxidant Potential and Mental Assessment.2021
- Author(s)
  Yatabe K, Muroi R, Kumai T, Kotani T, Somemura S, Yui N, Murofushi Y, Terawaki F, Kobayashi H, Yudoh K, Sakurai H, Miyano H, Fujiya H
- Journal Title
  
  Sports
  
  Volume: 9(3) Issue: 3 Pages: 36-36
- DOI
  10.3390/sports9030036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01698
[Journal Article] Pain Related to External Injury and Disorders Associated with Psychosocial Factors2018
- Author(s)
  Kanaka Yatabe, Ryota Muroi, Takanori Kumai, Takashi Kotoani, Toshio Kumai, Hiroto Fujiya
- Journal Title
  
  Biomedical Journal of Scientific & Technical Research (BJSTR)
  
  Volume: 10(2) Issue: 2 Pages: 1-20
- DOI
  10.26717/bjstr.2018.10.001924
- Data Source
  KAKENHI-PROJECT-17K01698
[Journal Article] Effects of Mountain Climbing on Mental Health and Stress Sensitivity in relation to the 5-HTTLPR gene.2017
- Author(s)
  Kanaka Yatabe, Naoko Yui, Sho Onodera, Hidetaka Yamaguchi, Akira Yoshioka, Kazuki Nishimura, Fumiko Terawaki, Takanori Kumai, Takashi Kotani, Ryota Muroi, Haruki Musha, Hiroyuki Sakurai, Toshio Kumai, Hiroto Fujiya.
- Journal Title
  
  Japanese Journal of Mountain Medicine
  
  Volume: 37(1) Pages: 103-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01698
[Journal Article] A bioinformatics-to-clinic sequential approach to analysis of prostate cancer biomarkers using TCGA datasets and clinical samples: a new method for precision oncology?2017
- Author(s)
  Hidekazu Yoshie, Anna S. Sedukhina, Kimino Minagawa, Keiko Oda, Shigeko Ohnuma,Nobuyuki Yanagisawa, Ichiro Maeda, Masayuki Takagi, Hiroya Kudo, Ryuto Nakazawa, Hideo Sasaki,Toshio Kumai, Tatsuya Chikaraishi, and Ko Sato
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 59 Pages: 99601-99611
- DOI
  10.18632/oncotarget.20448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19905, KAKENHI-PROJECT-15K10073
[Journal Article] A Subclassification of Basal-like Breast Cancer for Prognostic Prediction.2017
- Author(s)
  Tomoko Tsuruga, Keiko Oda, Hidekazu Yoshie, Ayano Shinagawa, Kimino Minagawa, Toshio Kumai, Ko Sato*, and Anna S Sedukhina.
- Journal Title
  
  International Journal of Innovative Research in Medical Science
  
  Volume: 2 Pages: 1031-1036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10073
[Journal Article] EPO signaling as a predictive marker of disease severity in RSV infection.2017
- Author(s)
  Ayano Shinagawa, Kimino Minagawa, Hidekazu Yoshie, Tomoko Tsuruga, Keiko Oda, Hitoshi Yamamoto, Toshio Kumai, Juan A Bernal, Ko Sato, Anna S Sedukhina.
- Journal Title
  
  International Journal of Innovative Research in Medical Science
  
  Volume: 2 Pages: 2455-8737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10073
[Journal Article] Effects of serotonin transporter gene polymorphism on mood during the period before the competition in Japanese ballet dancers.2016
- Author(s)
  Kanaka Yatabe, Toshio Kumai, Fujiya Hiroto, Naoko Yui, Satomi Kasuya, Yuka Murofushi, Keisuke Tateishi, Fumiko Terawaki, Hisao Miyano, Tadasu Oyama, Haruki Musha.
- Journal Title
  
  Integrative Molecular Medicine
  
  Volume: 3(6) Issue: 6 Pages: 818-825
- DOI
  10.15761/imm.1000253
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25350789
[Journal Article] Beyond resistance to PARP inhibition: Mechanisms and effective treatment options2015
- Author(s)
  Anna S Sedukhina, Elayanambi Sundaramoorthy, Masaki Hara, Toshio Kumai, Ko Sato
- Journal Title
  
  Cancer Cell & Microenvironment
  
  Volume: 2 Pages: 1-8
- DOI
  10.14800/ccm.821
- Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10073
[Journal Article] Association of Japanese-Specific Anxiety-Related Traints With a Polymorphism in the Serotonin Transporter Gene Under Pressure in Ballet Dancers.2014
- Author(s)
  Kanaka Yatabe, Toshio Kumai、Hiroto Fujiya, Naoko Yui, Keisuke Tateishi, Fumiko Terawaki, Haruki Musha, Satomi Kasuya, Hisaya Miyano, Tadasu, Oyama.
- Journal Title
  
  Clinical Journal of Sport Medicine
  
  Volume: 24(3)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25350789
[Journal Article] Comparative Study of Culture Conditions for Maintaining CYP3A4 and ATP-Binding Cassette Transporters Activity in Primary Cultured Human Hepatocytes.2011
- Author(s)
  Yuko Takeba, Naoki Matsumoto, Sachiko Takenoshita-Nakaya, Yoshie Harimoto, Toshio Kumai, Yuichi Kinoshita, Hiroshi Nakano, Takehito Ohtsubo, Shinichi Kobayashi
- Journal Title
  
  Journal of Pharmacological Sciences. vol.115、No.4
  
  Pages: 516-524
- NAID
  10029893533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590549
[Journal Article] Potential of lansoprazole as a novel probe for cytochrome P450 3A activity by measuring lansoprazole sulfone in human liver microsomes.2009
- Author(s)
  Yanagida Y, Watanabe M, Takeba Y,Kumai T, Matsumoto N, Hayashi M, Suzuki S, Kinoshita Y, Kobayashi S
- Journal Title
  
  Biol Pharm Bull. vol.32、No.8
  
  Pages: 1422-1426
- NAID
  130000117258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590549
[Presentation] Association between the Candidate Gene with Pain and Anxiety and Depression Factors of Ballet Dancers.2019
- Author(s)
  Kanaka Yatabe, Ryota Muroi, Takanori Kumai, Takashi Kotani, Fumiko Terawaki, Kimino Minagawa, Toshio Kumai, Hiroto Fujiya.
- Organizer
  The 39th Anxiety and Depression Conference (ADAA 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01698
[Presentation] 登山中の苦しさは、生体反応の何によって影響を受けるのか？―携帯型低酸素トレーニングキットを用いての検討―.2018
- Author(s)
  油井直子, 谷田部かなか, 寺脇史子, 武者春樹, 熊井隆智, 小谷貴史, 藤谷博人.
- Organizer
  第38回日本登山医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K01698
[Presentation] 低酸素トレーニングによる自覚的運動強度と生体反応変化－心理的検討.2018
- Author(s)
  谷田部かなか、油井直子、寺脇史子、武者春樹、室井良太、熊井隆智、小谷貴史、藤谷博人.
- Organizer
  平成30年度日本心理学会大山人間科学研究会第1回例会
- Data Source
  KAKENHI-PROJECT-17K01698
[Presentation] 運動条件の違いが潜在的抗酸化能と心理的(気分)評価に及ぼす影響.2018
- Author(s)
  谷田部かなか, 室井良太, 熊井隆智, 小谷貴史, 寺脇史子, 油井直子, 室伏由佳, 藤谷博人.
- Organizer
  第29回日本臨床スポーツ医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K01698
[Presentation] Effect of Climbing Mountain on Mental Health and Stress Sensitivity.2017
- Author(s)
  Kanaka Yatabe, Naoko Yui, Haruki Musha, Sho Onodera, Hidetaka Yamaguchi, Akira Yoshioka, Kazuki Nishimura, Fumiko Terawaki, Toshio Kumai, Hiroto Fujiya.
- Organizer
  The Joint Meeting of the 4th Congress of Asia-Pacific Society for Mountain Medicine and the 37th Annual Scientific Meeting of Japanese Society of Mountain Medicine.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01698
[Presentation] 健康成人における運動前後の生理的評価と主観的気分評価について2017
- Author(s)
  谷田部かなか, 油井直子, 武者春樹, 寺脇史子, 室井良太, 熊井隆智, 小谷貴史, 藤谷博人.
- Organizer
  第28回日本臨床スポーツ医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K01698
[Presentation] Association between the Serotonin Transporter Genotypes and Japanese-specific State-Trait Anxiety under Pressure.2016
- Author(s)
  Kanaka Yatabe, Masayuki Oda, Hiroto Fujiya, Naoko Yui, Satomi Kasuya, Yuka Murofushi, Keisuke Tateishi, Fumiko Terawaki, Hisao Miyano, Tadasu Oyama, Toshio Kumai, Haruki Musha.
- Organizer
  The 31st International Congress of Psychology (ICP2016)
- Place of Presentation
  Pacifico Yokohama (Yokohama, Kanagawa)
- Year and Date
  2016-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25350789
[Presentation] バレエダンサーにおける日本人特有のセロトニン多型との関連性.2015
- Author(s)
  谷田部かなか、熊井俊夫、小田昌幸、藤谷博人、油井直子、立石圭祐、寺脇史子、武者春樹、糟谷里美、宮埜壽夫、大山正.
- Organizer
  大山人間科学研究会平成26年度第3回例会
- Place of Presentation
  マイスペース新宿3丁目ビッグスビル店（東京）
- Year and Date
  2015-02-07
- Data Source
  KAKENHI-PROJECT-25350789
[Presentation] 肝疾患におけるCYPsおよびMDR-1の遺伝子多型について2007
- Author(s)
  熊井俊夫
- Organizer
  第28回日本臨床薬理学会
- Place of Presentation
  宇都宮
- Year and Date
  2007-11-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590516
[Presentation] Association of Japanese-specific Anxiety-related Traits with a Polymorphism in the Serotonin Transporter Gene under Pressure in Ballet Dancers.
- Author(s)
  Kanaka Yatabe, Toshio Kumai, Masayuki Oda, Hiroto Fujiya, Naoko Yui, Keisuke Tateishi, Fumiko Terawaki, Haruki Musha, Satomi Kasuya, Hisao Miyano, Tadasu Oyama.
- Organizer
  XXXIII FIMS World Congress of Sports Medicine
- Place of Presentation
  the Quebec City Convention Centre（Canada, Quebec City）
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25350789

1. TANAKA Masami (00171801)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KOBAYASHI Shinichi (20129836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. NAKANO Hiroshi (10241035)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. YATABE KANAKA (00387028)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. 藤谷博人 (50278008)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
6. TAKENOSHITA Sachiko (10386948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. MUSHA HARUKI (10182073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. ODA MASAYUKI (90737602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. MASUBUCHI Yoshiko (10081639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. AKAIKE Mari (70211000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. WATANABE Minoru (10191800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SATO KO (30598462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. Tozawa-Ono Akiko (90569865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KOIZUMI Hirotaka (10215155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NISHIKAWA Hiroyuki (90387077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YUI NAOKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. KASUYA SATOMI

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
18. OYAMA TADASU

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
19. MIYANO HISAO

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
20. TATEISHI KEISUKE

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
21. TERAWAKI FUMIKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
22. ISHIDATE MIYAKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. IGARASHI HIROSHI

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SAKURAI HIROYUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YAMASHITA MASAKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KUMAI Toshio 熊井 俊夫

熊井 俊夫 クマイ トシオ

熊井 秀夫 クマイ トシオ

Research Projects

Research Products

Co-Researchers

Many-sided analysis of the psychological stress reactions in sports.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effect of oestrogen with BRCA1 dysfunction on carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Association between the Serotonin Transporter Genotypes and Japanese-specific State-Trait Anxiety under Pressure in Sports (ballet dancers for example).

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Glycan profiling using formalin-fixed, paraffin-embedded tissues: Hippeastrum hybrid lectin is a sensitive biomarker for squamous cell carcinoma of the cervix

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Practical Use Study of Tailor made medicine : Accerelate of genotyping System and Feedback System to Primary Doctor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Tailor Made Therapy of Anti-Cancer Drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Disorder of steroidogeneis and defective repair of DNA in genetic disorder of lipid metabolism by the rat

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effects of Different Exercise Conditions on Antioxidant Potential and Mental Assessment.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pain Related to External Injury and Disorders Associated with Psychosocial Factors2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Mountain Climbing on Mental Health and Stress Sensitivity in relation to the 5-HTTLPR gene.2017

Author(s)

Journal Title

Data Source

[Journal Article] A bioinformatics-to-clinic sequential approach to analysis of prostate cancer biomarkers using TCGA datasets and clinical samples: a new method for precision oncology?2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Subclassification of Basal-like Breast Cancer for Prognostic Prediction.2017

Author(s)

Journal Title

Data Source

[Journal Article] EPO signaling as a predictive marker of disease severity in RSV infection.2017

Author(s)

Journal Title

Data Source

[Journal Article] Effects of serotonin transporter gene polymorphism on mood during the period before the competition in Japanese ballet dancers.2016

Author(s)

Journal Title

DOI

Data Source

KUMAI Toshio 熊井俊夫

熊井俊夫クマイトシオ

熊井秀夫クマイトシオ