MATSUMURA Yasuo 松村靖夫

… Alternative Names

松村靖夫マツムラヤスオ

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Researcher Number	40140230
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2002 – 2013: 大阪薬科大学, 薬学部, 教授 1998 – 2001: 大阪薬科大学, 薬学部, 助教授 1992 – 1996: 大阪薬科大学, 薬学部, 助教授 1991: 大阪薬科大学, 薬学部, 講師 1990: 大阪薬科大学, 第1薬理学教室, 講師 1986 – 1988: 大阪薬科大学, 薬理学教室, 助手
Review Section/Research Field	Principal Investigator General pharmacology / 血管生物学 / General pharmacology Except Principal Investigator Biological pharmacy / General pharmacology / 応用薬理学・医療系薬学
Keywords	Principal Investigator エンドセリン-1 / endothelin-1 / 高血圧 / エンドセリン / 血管内皮細胞 / HIF-1α / Rho-kinase / Na^+ / 急性腎不全 / hypertension … More / 腎障害 / エストラジオール / 性差 / 虚血 / エンドセリン変換酵素 / 血小板 / sex hormone / gender difference / raloxifene / hypoxia / monocrotaline / Pulmonary hypertension / endothelin / モノクロタリンピロル / エンドセリン受容体 / ラロシフェン / 性ホルモン / ラロキシフェン / 低酸素 / モノクロタリン / 肺性高血圧 / peroxynitrite / nitric oxide / Ca^<2+> exchanger / acute renal failure / ischemia / kidney / Ca^<2+>交換体 / ニトロチロシン / NOドナー / 活性酸素 / 酸化ストレス / Rhoキナーゼ / パーオキシナイトライト / 一酸化窒素 / Ca交換体 / Na / 腎臓 / renal failure / ET_B receptor / ET_B受容体 / deoxycorticosterone / renal injury / endothelin type-B receptor / endothelin type-A receptor / ET_Bレセプター / ETAレセプター / DOCA食塩高血圧 / デオキシコルチコステロン / エンドセリンBレセプター / エンドセリンAレセプター / アンジオテンシン / 卵巣摘除 / ノルエピネフリン / 虚血障害 / 女性ホルモン / ノルアドレナリン / 交感神経 / 再灌流 / 心臓 / ET_Aレセプター / TGF-β1 / TGF-beta_1(腫瘍増殖因子) … More Except Principal Investigator フォスフォラミドン / エンドセリン変換酵素 / プロテアソーム / エンドセリン / エンドセリン-1 / カリクレイン / 金属プロテアーゼ / 松果体 / プロカリクレイン / 血管内皮細胞 / アミノ酸配列 / 活性化酵素 / プロペプチド / カリクレイン前駆体 / Thio proteinase / Activator / Propeptide / Prokallikrein / Kallikrein / Rat kidney / デキサメサゾン / アルドステロン / 糖質コルチコイド / チオールプロテアーゼ / ラット腎 / reperfusion injury / ischemic / endothelin / hypertension / deoxycorticosterone / proteasome inhibitor / proteasome / 虚血再潅流障害 / 虚血再還流障害 / 高血圧 / デオキシコルチコステロン / プロテアソーム阻害薬 / カルモデュリン / カルシウム / レニン分秘 / 傍糸球体細胞 / 内皮細胞 / ETB受容体 / 一酸化窒素 / ET_Bレセプター / ET_Aレセプター / 慢性腎不全 / DOCA食塩高血圧 / 細胞周期 / 細胞分化 / 細胞増殖 / 血管平滑筋細胞 / 摘出潅流標本 / 変換酵素 / エンドペプチダーゼ-2 / ビッグエンドセリン / 免疫組織化学 / ラット脳 / ビッグエンドセリン-3 / ビッグエンドセリン-1 / 脳内分布 / 組織カリクレイン / エンドセリンー3 / ビッグエンドセリンー3 / エンドセリンー1 / ビッグエンドセリンー1 / 金属プロテア-ゼ / チオ-ルプロテア-ゼ Less

The significance of endothelin-1 and its receptors on nitric oxide production
- Principal Investigator
  
  OHKITA MAMORU
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University of Pharmaceutical Sciences
Ischemic organ injury and sympathetic nervous system : Roles of endothelin and angiotensin, and sex differencePrincipal Investigator
- Principal Investigator
  
  MATSUMURA Yasuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University of Pharmaceutical Sciences
Role of endothelin-1 and gender difference in the pathogenesis of pulmonary hypertensionPrincipal Investigator
- Principal Investigator
  
  MATSUMURA Yasuo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University of Pharmaceutical Sciences
Molecular mechanisms of ischemia/reperfusion-induced renal injuryPrincipal Investigator
- Principal Investigator
  
  MATSUMURA Yasuo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University of Pharmaceutical Sciences
Pathological role of endothelin ET_B receptorsPrincipal Investigator
- Principal Investigator
  
  MATSUMURA Yasuo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University of pharmaceutical Sciences, Assistant
Role of endothelin-1 in the yenal injury of hypertensionPrincipal Investigator
- Principal Investigator
  
  MATSUMURA Yasuo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University of Pharmaceutical Sciences
Role of proteasome in the development of hypertension
- Principal Investigator
  
  TAKAOKA Masanori
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
血管平滑筋細胞の分化・増殖に対するプロテアソームの制御機構について
- Principal Investigator
  
  高岡昌徳
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
エンドセリン-1の病態生理学的役割に関する研究
- Principal Investigator
  
  森本史郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Osaka University of Pharmaceutical Sciences
エンドセリン-1産生におけるエンドセリン変換酵素の役割と病態生理学的意義Principal Investigator
- Principal Investigator
  
  松村靖夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  Osaka University of Pharmaceutical Sciences
エンドセリンの代謝調節に関与する酵素の生化学的,組織化学的解析
- Principal Investigator
  
  森本史郎
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
血小板並びにTGF-β1によるエンドセリン-1産生促進作用とその病態生理学的意義Principal Investigator
- Principal Investigator
  
  松村靖夫
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  Osaka University of Pharmaceutical Sciences
血管内皮細胞におけるエンドセリン-1の産生機構
- Principal Investigator
  
  森本史郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University of Pharmaceutical Sciences
エンドセリン変換酵素の多様性と生化学的特性解析
- Principal Investigator
  
  高岡昌徳
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
血管内皮細胞のエンドセリン-1産生に対する血小板の作用Principal Investigator
- Principal Investigator
  
  松村靖夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  Osaka University of Pharmaceutical Sciences
血管内皮細胞におけるエンドセリン-1の産生機構
- Principal Investigator
  
  森本史郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University of Pharmaceutical Sciences
脳内組織カリクレインの産生機構とその調節機構に関する研究
- Principal Investigator
  
  森本史郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
血管内皮細胞におけるエンドセリンー1の産生機構
- Principal Investigator
  
  森本史郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University of Pharmaceutical Sciences
組織カリクレイン前駆体の活性化機構とその調節機構に関する研究
- Principal Investigator
  
  森本史郎
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
組織カリクレイン前駆体の活性化機構とその調節機構に関する研究
- Principal Investigator
  
  MORIMOTO Shiro
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
Activation mechanism of prokallikrein and its hormonal regulation in the kidney
- Principal Investigator
  
  MORIMOTO Shiro
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
レニン分泌細胞の機能に関する生理,生化学的研究
- Principal Investigator
  
  森本史郎
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences

All 2012 2011 2010 2008

All Journal Article Presentation

[Journal Article] Pathophysiological roles of endothelin receptors in cardiovascular diseases.2012
- Author(s)
  Ohkita M, Tawa M, Kitada K, Matsumura Y.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 119 Pages: 302-313
- NAID
  10031071269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590314
[Journal Article] Pathological Importance of the Endothelin-1/ET(B) Receptor System on Vascular Diseases.2012
- Author(s)
  Kitada K, Ohkita M, Matsumura Y.
- Journal Title
  
  Cardiology research and practice
  
  Volume: 2012 Pages: 731970-731970
- DOI
  10.1155/2012/731970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590314
[Journal Article] Pathophysiological roles of endothelin receptors in cardiovascular diseases2012
- Author(s)
  Ohkita M, Tawa M, Kitada K, Matsumura Y
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 119 Pages: 302-313
- NAID
  10031071269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590314
[Journal Article] Reduced NO production rapidly aggravates renal function through the NF-κB/ET-1/ETA receptor pathway in DOCA-salt-induced hypertensive rats.2012
- Author(s)
  Kimura K, Ohkita M, Koyama M, Matsumura Y.
- Journal Title
  
  Life Sciences
  
  Volume: 91 Issue: 13-14 Pages: 644-650
- DOI
  10.1016/j.lfs.2012.04.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590314
[Journal Article] Pathological Importance of the Endothelin-1/ET(B) Receptor System on Vascular Diseases2012
- Author(s)
  Kitada K, Ohkita M, Matsumura Y
- Journal Title
  
  Cardiol. Res. Pract.
  
  Pages: 731-970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590314
[Journal Article] Reduced NO production rapidly aggravates renal function through the NF-κB/ET-1/ETA receptor pathway in DOCA-salt-induced hypertensive rats2012
- Author(s)
  Kimura K, Ohkita M, Koyama M, Matsumura Y
- Journal Title
  
  Life Sci.
  
  Volume: 91 Pages: 644-650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590314
[Journal Article] Contribution of nitric oxide in big endothelin-1-induced cardioprotective effects on ischemia/reperfusion injury in rat hearts.2011
- Author(s)
  Masashi Tawa, Taiki Fukumoto, Mamoru Ohkita, Naoto Yamashita, Ayman Geddawy, Takeshi Imamura, Kazuhide Ayajiki, Tomio Okamura, Yasuo Matsumura
- Journal Title
  
  J.Cardiovasc.Pharmacol. 57
  
  Pages: 575-578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590266
[Journal Article] Effects of exogenous big endothelin-1 on postischemic cardiac dysfunction and norepinephrine overflow in rat hearts.2011
- Author(s)
  Masashi Tawa, Taiki Fukumoto, Mamoru Ohkita, Naoto Yamashita, Ayman Geddawy, Takeshi Imamura, Kazuhide Ayajiki, Tomio Okamura, Yasuo Matsumura
- Journal Title
  
  Hypertens.Res. 34
  
  Pages: 218-224
- NAID
  10031163156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590266
[Journal Article] Postconditioning improves postischemic cardiac dysfunction independently of norepinephrine overflow after reperfusion in rat hearts : Comparison with preconditioning.2010
- Author(s)
  Masashi Tawa, Taiki Fukumoto, Naoto Yamashita, Mamoru Ohkita, Kazuhide Ayajiki, Tomio Okamura, Yasuo Matsumura
- Journal Title
  
  J.Cardiovasc.Pharmacol. 55
  
  Pages: 6-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590266
[Journal Article] Role of endogenous endothelin-1 in post-ischemic cardiac dysfunction and norepinephrine overflow in rat hearts.2008
- Author(s)
  Masashi Tawa, Taiki Fukumoto, Mamoru Ohkita, Yasuo Matsumura
- Journal Title
  
  Eur.J.Pharmacol. 591
  
  Pages: 182-188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590266
[Journal Article] Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts.2008
- Author(s)
  Tetsumasa Sasaoka, Yasuhiro Egi, Masashi Tawa, Ai Yamamoto, Mamoru Ohkita, Masanori Takaoka, Tomoyuki Maruyama, Toshiaki Akira, Yasuo Matsumura
- Journal Title
  
  J.Cardiovasc.Pharmacol. 52
  
  Pages: 176-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590266
[Presentation] 血管内皮細胞のNO産生におけるET_B受容体の役割2012
- Author(s)
  小山真季, 鈴木理恵, 大喜多守, 松村靖夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23590314
[Presentation] 血管内皮細胞のNO産生におけるETB受容体の役割2012
- Author(s)
  小山真季、鈴木理恵、大喜多守、松村靖夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23590314
[Presentation] Reduced NO production rapidly aggravates renal function through the NF-κB/ET-1/ET_A receptor pathway in DOCA-salt-induced hypertensive rats2011
- Author(s)
  Mamoru Ohkita, Kimihiro Kimura, Maki Koyama, Yasuo Matsumura
- Organizer
  The Twelfth International Conference on Endothelin
- Place of Presentation
  Cambridge, United Kingdom
- Data Source
  KAKENHI-PROJECT-23590314
[Presentation] モノクロタリン誘発性肺高血圧ラットにおけるラロキシフェンの病態改善効果2008
- Author(s)
  松村靖夫
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590232

1. TAKAOKA Masanori (50140231)

# of Collaborated Projects: 19 results

# of Collaborated Products: 0 results
2. MORIMOTO Shiro (60067270)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
3. OHKITA Mamoru (60449824)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
4. URATA Hidehtio (80211085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 喜多紗斗美

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MATSUMURA Yasuo 松村 靖夫

松村 靖夫 マツムラ ヤスオ

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Ischemic organ injury and sympathetic nervous system : Roles of endothelin and angiotensin, and sex differencePrincipal Investigator

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Role of endothelin-1 and gender difference in the pathogenesis of pulmonary hypertensionPrincipal Investigator

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Molecular mechanisms of ischemia/reperfusion-induced renal injuryPrincipal Investigator

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Pathological role of endothelin ET_B receptorsPrincipal Investigator

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Role of endothelin-1 in the yenal injury of hypertensionPrincipal Investigator

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エンドセリン-1産生におけるエンドセリン変換酵素の役割と病態生理学的意義Principal Investigator

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血小板並びにTGF-β1によるエンドセリン-1産生促進作用とその病態生理学的意義Principal Investigator

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MATSUMURA Yasuo 松村靖夫

松村靖夫マツムラヤスオ