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Kobayashi Hideyuki  小林 英幸

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… Alternative Names

KOBAYSHI Hideyuki  小林 英幸

KOBAYASHI Hideyuki  小林 英幸

小林 英幸  コバヤシ ヒデユキ

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Researcher Number 40148953
Other IDs
External Links
Affiliation (Current) 2025: 産業医科大学, 名誉教授、学長等, 名誉教授
Affiliation (based on the past Project Information) *help 2010 – 2012: 産業医科大学, 医学部, 教授
2003 – 2006: 宮崎大学, 医学部, 助教授
1995 – 2002: 宮崎医科大学, 医学部, 助教授
1992: 産業医科大学, 医学部, 講師
1989: 産業医科大学, 医学部・薬理学, 助手
Review Section/Research Field
Principal Investigator
応用薬理学・医療系薬学 / Applied pharmacology / Neurochemistry/Neuropharmacology / General pharmacology
Except Principal Investigator
General pharmacology / Neurochemistry/Neuropharmacology / Biological Sciences / Obstetrics and gynecology
Keywords
Principal Investigator
脳微小血管 / 発現調節 / regulation of expression / 脳浮腫 / アストロサイト / アクアポリン / ノーザンブロット / イムノブロット / GTP結合蛋白質 / スナネズミ … More / 遺伝子 / 受容体 / 脳虚血 / agrin / glucocorticoid / raft / brain edema / endothelial cells / aquaporin / brain microvessel / 網膜 / アグリン / 糖質コルチコイド / ラフト / 内皮細胞 / localization / intracellular trafficking / nerve growth factor / cell differentiation / cell adhesion molecule / β-subunit / voltage-dependent Na+ channel / MAPキナーゼ / PC12細胞 / GFP / 強制発現 / 分化 / 電位依存性Na+チャネル / 局在 / 細胞内輸送 / 神経成長因子 / 細胞分化 / 細胞接着分子 / β-サブユニット / 電位依存性Na^+チャネル / Immortalized cell / Cytotoxic edema / Regulation of expression / Astrocytes / hypoxia / Ischemia / Cultured endothelial cell / Aquaporin / Cerebral microvessel / 培養 / ウエスタンブロット / RT-PCR / 水チャネル / 不死化細胞 / 細胞障害性浮腫 / 虚血・低酸素 / 培養内皮細胞 / 生体防御機構 / α抗原 / 生理活性ペプチド / 遺伝子組み換え / BCG / ワクチン / 感染症 / ベロ毒素 / 腸管出血性大腸菌 / ストレプトゾトシン / 培養細胞 / 糖尿病 / 神経伝達 / アドレナリン作動性 … More
Except Principal Investigator
Gene expression / Northern blot / Western blot / Down-regulation / Calcium / Up-and down-regulation / 妊娠子宮 / 細胞膜発現調節 / Binding / Sodium channel / lithium / insulin / Neuroprotective drug / Calpain / Protein phosphatase / Protein kinase / Ca^<2+> signaling / Ca^<2+> oscillation / Voltage-dependent Na^+ channels / Exocytosis / Neuroprotective drugs / Protein kinases / Sodium channels / 早産 / 脱落膜 / 胎盤 / 子宮収縮抑制 / RAMP / アドレノメデュリン / 血清除去 / 培養副腎髄質細胞 / Naチャネル / Protein kinase C / troglitazone / lysosphosphatidic acid / insulin-like growth factor / Ca2+ overload / cell surface expression / Nav1.7 Na+ channel / glycogen synthase kinase-3 / プリオン・ペプタイド / β-アミロイド・ペプタイド / 電位依存性Na+チャネル / 副腎髄質クロマフィン細胞 / インターナリゼーション / β-アミロイド / GSK-3β / IGF-I / Hsp90 / lysophosphatidic acid / glycogen synthase kinase-3β / heat shock protein 90 / 糖鎖付加 / 翻訳後修飾 / Na^+チャネル / トログリタゾン / lysohosphatidic acid / リチウム / insulin-like growth factor-I / Ca^<2+>過負荷 / 細胞膜発現 / Na_v1.7Na^+チャネル / premature labor / mRNA expression / decidua / placenta / pregnant uterus / tocolysis / myometrium / adrenomedullin / mRNA発現 / 子宮平滑筋 / Ca-ATPase / Calcineurin / Voltage-dependent sodium channels / Ca^<2+>signaling / Ca^<2+>oscillation / Pregnant uterus / Vascular smooth muscle cell / Glia cell / Brain microvessel endothelial cell / Receptor / Bioactive peptide / Catecholamine / Brain microvessels / Autocrine regulation / Nicotinic receptors / Tyrosine hydroxylase / Uterus / Adrenomedullin family / Oligodendroglial cells / Choroid plexus / Microvessels / Adrenal chromaffin cells / CRLR / PAMP / Adrenomedullin / 平滑筋細胞 / グリア筋細胞 / 脳微小血管内皮細胞 / 遺伝子発現 / レセプター / 生理活性ペプチド / Antiepileptics / C kinase family / mRNA発現増加 / オキシトシン / プロスタグランジンF_<2α> / ブラジキニン / AMノックアウトマウス / RAMP2 / 子宮収縮制御 / SAPK / p38 MAPK / JNK / p38MAPK / ERK / MAPKファミリー / 電位依存性Naチャネル / Caイオン / イムノフィリン / 神経保護薬 / MAPカイネース / プロテインカイネースC / 細胞内輸送 / Internalization / C kinase isoform / ^<22>Na+ influx / 機能調節 / インタ-ロイキン / 副腎髄質 Less
  • Research Projects

    (18 results)
  • Research Products

    (44 results)
  • Co-Researchers

    (14 People)
  •  Development of prevention and treatment methods for infection by enterohemorrhagic Escherichia coli O157 based on bio-protect ive mechanismsPrincipal Investigator

    • Principal Investigator
      KOBAYSHI Hideyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  アドレノメデュリンの妊娠子宮・収縮抑制機序:早産治療薬としての基礎研究

    • Principal Investigator
      和田 明彦
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      University of Miyazaki
  •  Regulatory mechanisms of expression and localization of aquaporin water channels in brain microvesselsPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Hideyuki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      University of Miyazaki
  •  Voltage-dependent Na+ channel: quality control and stress response.

    • Principal Investigator
      WADA Akihiko
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      University of Miyazaki
  •  Physiological function of voltage-dependent Na^+ channel β-subunit as an adhesion moleculePrincipal Investigator

    • Principal Investigator
      KOBAYASHI Hideyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      University of Miyazaki
      宮崎医科大学
  •  Inhibitory effect of adrenomedullin on uterine contraction

    • Principal Investigator
      YANAGITA Toshihiko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Miyazaki Medical College
  •  Regulatory mechanism of aquaporin expression in cerebral microvessels : its pathophysiological significancePrincipal Investigator

    • Principal Investigator
      KOBAYASHI Hideyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      宮崎医科大学
  •  Naチャネルの細胞膜発現調節機構におけるMAPカイネースの役割

    • Principal Investigator
      柳田 俊彦
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General pharmacology
    • Research Institution
      宮崎医科大学
  •  Regulation of cell surface expression of voltage-dependent sodium channels by multiple calcium signalings : their mRNA levels and intracellular trafficking

    • Principal Investigator
      WADA Akihiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Miyazaki Medical College
  •  Naチャネルの細胞膜発現調節:サブユニットmRNA変動と細胞内輸送・局在化機構

    • Principal Investigator
      YANAGITA Toshihiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General pharmacology
    • Research Institution
      宮崎医科大学
  •  Physiological function and gene expression of adremnomedullinfamily : adrenal medullary cells and isolated blood vessels

    • Principal Investigator
      WADA Akihiko
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Miyazaki Medical College
  •  Intracellular mechanisms regulating cell surface expression of Na channels : Na channel subunit mRNA levels and intracellular trafficking.

    • Principal Investigator
      WADA Akihiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Miyazaki Medical College
  •  Cカイネースによる細胞膜Naチャネルdown-regulationの細胞内機序

    • Principal Investigator
      和田 明彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      宮崎医科大学
  •  糖尿病による脳微小血管のGTP結合蛋白質αサブユニットの変化Principal Investigator

    • Principal Investigator
      小林 英幸
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      宮崎医科大学
  •  CカイネースによるNaチャネル発現の制御と細胞応答の修飾

    • Principal Investigator
      WADA Akihiko
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      宮崎医科大学
  •  虚血による脳GTP結合蛋白質とその遺伝子発現の変化Principal Investigator

    • Principal Investigator
      小林 英幸
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      宮崎医科大学
  •  脳虚血による脳アドレナリン作動性受容体とその遺伝子発現の変化Principal Investigator

    • Principal Investigator
      小林 英幸
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  副腎髄質系と免疫活性物質

    • Principal Investigator
      泉 太
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      University of Occupational and Environmental Health, Japan

All 2013 2012 2011 2010 2007 2006 2005 2004 2003

All Journal Article Presentation

  • [Journal Article] Antigen 85A and mycobacterial DNA-binding protein 1 are targets of immunoglobulin G in individuals with past tuberculosis.2013

    • Author(s)
      Osada-Oka M., Tateishi Y., Hirayama Y., Ozeki Y., Niki M., Kitada S., Maekura R., Tsujimura K., Koide Y., Ohara N., Yamamoto T., Kobayashi K., Matsumoto S.
    • Journal Title

      Microbiol. Immunol.

      Volume: 57 Pages: 30-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Journal Article] Investigation of Encephalopathy Caused by Shiga Toxin 2c-Producing Escheriohia ooli Infection in Mice2013

    • Author(s)
      Amran M. Y., Fujii J., Suzuki S. 0., Kolling G. L.,Villanueva A. M.,Kainunla M., Kobayashi H., Kanleyanla H. and Yoshida S
    • Journal Title

      PLoS One

      Volume: 8 Issue: 3 Pages: e58959-e58959

    • DOI

      10.1371/journal.pone.0058959

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590256, KAKENHI-PROJECT-23500497
  • [Journal Article] Antigen 85A and mycobacterial DNA-binding protein 1 are targets of immunoglobulin G in individuals with past tuberculosis2013

    • Author(s)
      Osada-Oka M, Tateishi Y, Hirayama Y, Ozeki Y, Niki M, Kitada S, Maekura R, Tsujimura K, Koide Y, Ohara N, Yamamoto T, Kobayashi K, Matsumoto S
    • Journal Title

      Microbiol. Immunol

      Volume: 57 Pages: 30-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Journal Article] Protection by recombinant Bacillus Calmette-Guerin vaccine expression Shiga toxin 2B subunit against Shiga toxin producing Escherichia coli in mice2012

    • Author(s)
      Fujii J., Naito M., Yutsudo T., Heatherly D., Yamada T., Kobayashi H., Yoshida S. and Obrig T
    • Journal Title

      Clin. Vac. Imnunol

      Volume: 19 Issue: 12 Pages: 1932-1937

    • DOI

      10.1128/cvi.00473-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590256, KAKENHI-PROJECT-23500497
  • [Journal Article] Lipidphenotype of two distinct subpopulations of Vayo ohaoteri um bovis Bacillus Calmette-Guerin Tokyo 172 substrain2011

    • Author(s)
      Naka T., Maeda S., Niki M., Ohara N., Yamamoto S.,Yano I.,Maeyama J.,Ogura H., Kobayashi K.,Fujiwara N
    • Journal Title

      Biol. Chem

      Volume: 286 Pages: 44153-44161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Journal Article] Lipid phenotype of two distinct subpopulations of Mycobacterium bovis Bacillus Calmette-Guerin Tokyo 172 substrain2011

    • Author(s)
      Naka T., Maeda S., Niki M., Ohara N, Yamamoto S., Yano I., Maeyama J., Ogura H., Kobayashi K., Fujiwara N.
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 44153-44161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Journal Article] アグリン(キーワード解説)2010

    • Author(s)
      小林英幸、森井宏幸
    • Journal Title

      日薬理誌

      Volume: 135 Pages: 215-216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Journal Article] アグリン2010

    • Author(s)
      小林英幸, 森井宏幸
    • Journal Title

      日薬理誌

      Volume: 135 Pages: 215-216

    • NAID

      10026439433

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Journal Article] Differential expression of Kir4.1 and aquaporin 4 in the retina from endotoxin-induced uveitis rat.2007

    • Author(s)
      Liu X.Q., Kobayashi H., Jin Z.B., Wada A., Nao-I N.
    • Journal Title

      Molecular Vision 13

      Pages: 309-317

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590473
  • [Journal Article] Induction of aquaporin 1 by dexamethasone in lipid rafts in immortalized brain microvascular endothelial cells.2006

    • Author(s)
      Hideyuki Kobayashi et al.
    • Journal Title

      Brain Research 1123・1

      Pages: 12-19

    • NAID

      120007122978

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300119
  • [Journal Article] Induction of aquaporin 1 by dexamethasone in lipid rafts in immortalized brain microvascular endothelial cells2006

    • Author(s)
      Kobayashi H., Yokoo H., Yanagita T., Satoh S., Kis B., Deli M., Niwa M., Wada A.
    • Journal Title

      Brain Research 1123

      Pages: 12-19

    • NAID

      120007122978

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590473
  • [Journal Article] Induction of aquaporin 1 by dexamethasone in lipid rafts in immortalized brain microvascular endothelial cells2006

    • Author(s)
      Kobayashi H. et al.
    • Journal Title

      Brain Res 1123

      Pages: 12-19

    • NAID

      120007122978

    • Data Source
      KAKENHI-PROJECT-17590473
  • [Journal Article] Induction of aquaporin 1 by dexamethasone in lipid rafts in immortalized brain microvascular endothelial cells.2006

    • Author(s)
      Kobayashi H et al.
    • Journal Title

      Brain Research 1123(1)

      Pages: 12-19

    • NAID

      120007122978

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300119
  • [Journal Article] Constitutive activity of glycogen synthase kinase-3beta : Positive regulation of steady-state levels of insulin receptor substrates-1 and-2 in adrenal chromaffin cells.2006

    • Author(s)
      Nemoto T., Yokoo H., Satoh S., Yanagita T., Sugano T., Yoshikawa N., Maruta T., Kobayashi H., Wada A.
    • Journal Title

      Brain Research 1110

      Pages: 1-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590473
  • [Journal Article] Enhancement of insulin-induced PI3K/Akt/GSK-3 beta and ERK signaling by neuronal nicotinic receptor/PKC-alpha/ERK pathway : up-regulation of IRS-1/-2 mRNA and protein in adrenal chromaffin cells.2006

    • Author(s)
      Sugano T., Yanagita T., Yokoo H., Satoh S., Kobayashi H., Wada A.
    • Journal Title

      Journal of Neurochemistry 98

      Pages: 20-33

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590473
  • [Journal Article] Induction of aquaporin 1 by dexaraethasone in lipid rafts in immortalized brain microvascular endothelial cells2006

    • Author(s)
      Kobayashi H. et al.
    • Journal Title

      Brain Res. 1123

      Pages: 12-19

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590473
  • [Journal Article] Insulin induces internalization of the 5-HT2A receptor expressed in HEK293 cells.2005

    • Author(s)
      Ohkura M., Tanaka N., Kobayashi H., Wada A., Nakai J., Yamamoto R.
    • Journal Title

      European Journal of Pharmacology 518

      Pages: 18-21

    • NAID

      40015392245

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590473
  • [Journal Article] New twist on neuronal insulin receptor signaling in health, disease, and therapeutics.2005

    • Author(s)
      Wada A., Yokoo H., Yanagita T., Kobayashi H.
    • Journal Title

      Journal of Pharmacological Sciences 99

      Pages: 128-143

    • NAID

      10025730645

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590473
  • [Journal Article] Relaxant effect of adrenomedullin on bovine isolated iris sphincter muscle under resting conditions.2005

    • Author(s)
      Uchikawa Y., Okano M., Sawada A., Asada Y., Kobayashi H., Wada A., Nao-i N., Ohkura M., Tanaka N., Yamamoto R.
    • Journal Title

      Clinical and Experimental Pharmacology and Physiology 32

      Pages: 675-680

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590473
  • [Journal Article] Molecular mechanisms and drug development in aquaporin water channel diseases : aquaporins in the brain.2004

    • Author(s)
      Hideyuki Kobayashi et al.
    • Journal Title

      Journal of Pharmacological Sciences 96・3

      Pages: 264-270

    • NAID

      10014167168

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300119
  • [Journal Article] Expression of adrenomedullin and proadrenomedullin N-terminal 20 peptide in PC12 cells after exposure to nerve growth factor2004

    • Author(s)
      Kobayashi H. et al.
    • Journal Title

      Neuroscience 125

      Pages: 973-980

    • NAID

      120007122980

    • Data Source
      KAKENHI-PROJECT-15500263
  • [Journal Article] Expression of adrenomedullin and proadrenomedullin N-terminal 20 peptide in PC12 cells after exposure to nerve growth factor.2004

    • Author(s)
      Kobayashi H. et al.
    • Journal Title

      Neuroscience 125

      Pages: 973-980

    • NAID

      120007122980

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15500263
  • [Journal Article] Molecular mechanisms and drug development in aquaporin water channel diseases : aquaporins in the brain.2004

    • Author(s)
      Kobayashi H et al.
    • Journal Title

      Journal of Pharmacological Sciences 96(3)

      Pages: 264-270

    • NAID

      10014167168

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300119
  • [Journal Article] Molecular mechanisms and drug development in aquaporin water channel diseases : Aquaporin in the brain2004

    • Author(s)
      Kobayashi H. et al.
    • Journal Title

      J.Pharmacol.Sci. 96

      Pages: 264-270

    • NAID

      10014167168

    • Data Source
      KAKENHI-PROJECT-15500263
  • [Journal Article] Expression of adrenomedullin and proadrenomedullin N-terminal 20 peptide in PC12 cells after exposure to nerve growth factor.2004

    • Author(s)
      Kobayashi H et al.
    • Journal Title

      Neuroscience 125(4)

      Pages: 973-980

    • NAID

      120007122980

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300119
  • [Journal Article] Molecular mechanisms and drug development in aquaporin water channel diseases : aquaporins in the brain.2004

    • Author(s)
      Hideyuki Kobayashi et al.
    • Journal Title

      Journal of Pharmacological Sciences 96

      Pages: 264-270

    • NAID

      10014167168

    • Data Source
      KAKENHI-PROJECT-16300119
  • [Journal Article] Expression of adrenomedullin and proadrenomedullin N-terminal 20 peptide in PC12 cells after exposure to nerve growth factor.2004

    • Author(s)
      Hideyuki Kobayashi et al.
    • Journal Title

      Neuroscience 125・4

      Pages: 973-980

    • NAID

      120007122980

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300119
  • [Journal Article] Pathophysiological function of adrenomedullin and proadrenomedullin N-terminal peptides in adrenal chromaffin cells.2003

    • Author(s)
      Kobayashi H. et al.
    • Journal Title

      Hypertension Research 26

    • NAID

      120007122979

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15500263
  • [Presentation] 抗酸菌のslidingmotilityと非貧食細胞への取り込みの関連性2012

    • Author(s)
      岡部真裕子,大原直也,藤原永年,中崇,阿戸学,小林和夫
    • Organizer
      第82回実験結核研究会
    • Place of Presentation
      広島国際会議場、広島
    • Year and Date
      2012-05-09
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] 結核菌/BCGのストレプトマイシン耐性・依存性に関する新たな知見2012

    • Author(s)
      佐藤法仁,阿戸学,黒田誠,山崎利雄,松村隆之,関塚剛史,中山真彰,井上哲圭,本田尚子,土田耕三,小林和夫,大原直也
    • Organizer
      第82回実験結核研究会
    • Place of Presentation
      広島国際会議場、広島
    • Year and Date
      2012-05-09
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] Lipid Phenotypes of Two Distinct Subpopulations of Mycobacterium bovis Bacillus Calmette-Guerin Tokyo 172 Substrain and their Host Responses.2012

    • Author(s)
      Naka T., Maeda S., Niki M., Ohara N., Yamamoto S., Yano I., Maeyama J., Ogura H., Kobayashi K., Shibata M., Fujiwara N.
    • Organizer
      American Society for Microbiology 112th General Meeting
    • Place of Presentation
      Moscone Center, San Francisco,U.S.A.
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] 抗酸菌のsliding motilityと非貪食細胞への取り込みの関連性.2012

    • Author(s)
      岡部真裕子,大原直也,藤原永年,中崇,阿戸学,小林和夫
    • Organizer
      第82回実験結核研究会
    • Place of Presentation
      広島国際会議場、広島
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] Lipid Phenotypes of Two Distinct Subpopulations of Mycobacterium bovis Bacillus Calnlette-Guerin Tokyo 172 Substrain and their Host Responses2012

    • Author(s)
      Naka, T.,Maeda S.,Niki M., Ohara N.,Yamamoto S.,Yano I.,Maeyama J.,Ogura H.,Kobayashi K., Shibata M., and Fujiwara N
    • Organizer
      American Society for Microbiology 112th General Meeting
    • Place of Presentation
      Moscone Center, San Francisco, U.S.A
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] ストレプトマイシン依存性結核菌18bの依存性に関与する遺伝子変異の解明と新たなストレプトマイシン耐性を誘導する変異の発見2012

    • Author(s)
      佐藤法仁,山崎利雄,小林和夫,大原直也
    • Organizer
      第87回日本結核病学会総会
    • Place of Presentation
      広島国際会議場、広島
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] ストレプトマイシン依存性結核菌18bの依存性に関与する遺伝子変異の解明と新たなストレプトマイシン耐性を誘導する変異の発見.2012

    • Author(s)
      佐藤法仁,山崎利雄,小林和夫,大原直也
    • Organizer
      第87回日本結核病学会総会
    • Place of Presentation
      広島国際会議場、広島
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] 結核菌/BCGのストレプトマイシン耐性・依存性に関する新たな知見.2012

    • Author(s)
      佐藤法仁,阿戸学,黒田誠,山崎利雄,松村隆之,関塚剛史,中山真彰,井上哲圭,本田尚子,土田耕三,小林和夫,大原直也
    • Organizer
      第82回実験結核研究会
    • Place of Presentation
      広島国際会議場、広島
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] Gene expression profile of in a thymidine synthase ThyX-deletion mutant of Mycobacterium bovis BCG2011

    • Author(s)
      Ohara N., Satoh N., Nakayama M., Okabe M, Kobayashi K
    • Organizer
      XIII International Congress of Bacteriology and Applied Microbiology. International Union of Microbiological Societies
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] Identification of the novel mutations in 16S rRNA gene of the substrains of a streptomycin-dependent Mycobacterium tuberculosis Strain18b which confer streptomycin resistance in Mycobacterium2011

    • Author(s)
      Sato N., Ato M., Matsumura T., Yamazaki T., Sekizuka T., Kuroda M., Nakayama M., Kobayashi K., Ohara N
    • Organizer
      XIII International Congress of Bacteriology and Applied Microbiology. International Union of Microbiological Societies
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] Streptomycin依存性結核菌における遺伝子変異の解明とStreptomycin耐性を誘導する新たな遺伝子変異2011

    • Author(s)
      佐藤法仁、阿戸学、松村隆之、山崎利雄、関塚剛史、黒田誠、中山真章、井上哲圭、本田尚子、土田耕三、小林和夫、大原直也
    • Organizer
      第64回日本細菌学会中国・四国支部総会
    • Place of Presentation
      岡山大学(岡山)
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] Analysis of the 16S rRNA gene of the streptomycin-dependent Mycobacterium tuberculosis strain 18b and phenolypic revenant strains2011

    • Author(s)
      Sato N., Ato M., Yamazaki T., Kuroda M., Matsumura T., Sekizuka T., Nakayama M., Honda, N., Tsuchida, K., Kobayashi K., Ohara N
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] 抗酸菌におけるセカンドメッセンジャーの利用2011

    • Author(s)
      佐藤法仁、中山真彰, 岡部真裕子, 小林和夫、大原直也
    • Organizer
      第86回実験結核研究会
    • Place of Presentation
      大妻講堂(東京)
    • Year and Date
      2011-06-01
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] DNAマイクロアレイを用いたBCG Tokyo 172-1に存在するサブポピュレーションの遺伝子発現の比較検討2010

    • Author(s)
      大原直也, 山本三郎, 瀧井猛将, 藤原永年, 前山順一, 小林和夫
    • Organizer
      第80回実験結核研究会
    • Place of Presentation
      京都テルサ(京都)
    • Year and Date
      2010-05-19
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] Analysis of RD16 locus in the BCG Tokyo 172 genome.Forty-fifth Joint Research Conference on Leprosy and Tuberculosis.2010

    • Author(s)
      Ohara, N., Okabe, M., Yamamoto, S., Takii, T., Fujiwara, N., Maeyama, J., Nakayama, M., Kobayashi, K.
    • Organizer
      The United State-Japan Cooperative Medical Science Program
    • Place of Presentation
      Broad Institute (Cambridge, Massachusetts, U.S.A.)
    • Year and Date
      2010-07-15
    • Data Source
      KAKENHI-PROJECT-22590256
  • [Presentation] BCG Tokyo 172株に存在するサブポピュレーション間の遺伝子発現の比較発現の比較検討2010

    • Author(s)
      大原直也, 岡部真裕子, 山本三郎, 瀧井猛将, 藤原永年, 前山順一, 佐藤法仁, 井上哲圭, 小林和夫
    • Organizer
      第80回実験結核研究会
    • Place of Presentation
      京都テルサ(京都)
    • Year and Date
      2010-05-19
    • Data Source
      KAKENHI-PROJECT-22590256
  • 1.  WADA Akihiko (30131949)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 7 results
  • 2.  YANAGITA Toshihiko (60295227)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 4 results
  • 3.  YOKOO Hiroki (30332894)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 4 results
  • 4.  YAMAMOTO Ryuichi (10094111)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  UEZONO Yasuhito (20213340)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  KITAMURA Kazuo (50204912)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MORII Hiroyuki (60141743)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  FUJII Jun (60271441)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  泉 太 (90028506)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  柳原 延章 (80140896)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  占部 正信 (00094087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  池ノ上 克 (60232211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  大原 直也 (70223930)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 20 results
  • 14.  SAKATA Tsuneaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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