KATO Nobuyuki 加藤宣之

… Alternative Names

加藤宣之カトウノブユキ

加藤宜之カトウノブユキ

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Researcher Number	40150883
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016 – 2018: 岡山大学, 医歯薬学総合研究科, 教授 2015: 岡山大学, 大学院医歯薬学総合研究科, 教授 2012 – 2015: 岡山大学, 医歯(薬)学総合研究科, 教授 2012: 岡山大学, 大学院・医歯薬学総合研究科, 教授 2005: 岡山大学, 大学院医歯薬学総合研究科, 教授 … More 2004: 岡山大学, 大学院・医歯学総合研究科, 教授 2001: 岡山大学, 大学院・医歯学総合研究科, 教授 1999 – 2000: 岡山大学, 医学部, 教授 1999: National Cancer Center Research Institute, Virology Division, Section Chief, ウイルス部, 室長 1997 – 1999: 国立がんセンター, 研究所・ウイルス部, 室長 1998: 室長 1998: 国立がんセンター, 研究所ウイルス部, 室長 1998: National Cancer Center Research Institute, Section Chief, ウイルス部, 室長 1996: 国立がんセンター研究所, ウィルス部, 室長 1994: 国立がんセンター研究所, ウイルス部, 室長 1993 – 1994: 国立がんセンター, 研究所・ウイルス部, 室長 1990: 国立がんセンター研究所, ウィルス部, 研究員 1990: National Cancer Center Research Institute Virology Division Research Associate, ウイルス部, 研究員 1988: 国立がんセンター研究所, ウィルス部, 研究員 Less
Review Section/Research Field	Principal Investigator Virology / Virology / 物質生物化学 / Biological Sciences Except Principal Investigator Virology / Parasitology (including sanitary zoology)
Keywords	Principal Investigator C型肝炎ウイルス / コア蛋白質 / 転写調節能 / レポーターアッセイシステム / 感染症 / ウイルス / マイクロアレイ解析 / Exosome / 遺伝子発現変動 / 分子生物学 … More / DNA修復 / CAリピート / マイクロサテライト不安定性 / cDNA発現アレイ / RT-PCR法 / 持続感染細胞 / 超可変領域 / 長期HBV複製細胞 / 癌 / 発現制御 / 遺伝子 / HBV長期複製細胞 / HCV長期複製細胞 / B型肝炎ウイルス(HBV) / C型肝炎ウイルス(HCV) / HBV感受性 / 長期HCV複製細胞 / B型肝炎ウイルス / C 型肝炎ウイルス / 遺伝子解析 / 薬理作用機序 / 抗ウイルス剤 / 微生物 / Structural analysis / Genome structure / Nucleotide sequence / Genetic information / Virus genome / RNA virus / Molecular biology / C-type hepatitis / ウィルスゲノム / RNAウィルス / 構造解析 / ゲノム構造 / 塩基配列 / 遺伝情報 / ウイルスゲノム / RNAウイルス / C型肝炎 / DNA結合性蛋白質 / Z_n^<2+>結合フィンガー構造 / 細胞遺伝子 / 転写制御 / 内在性レトロウィルス / RNA複製増殖 / ヒト不死化肝細胞 / miRNA発現変動 / 長期継代培養 / 宿主因子 / HCV RNA複製細胞 / 感染増殖システム / 遺伝子型1b / 全長HCV RNA複製細胞 / サブジェノミックレプリコン / PH5CH8細胞 / CTGF / TGF-β / HuH-7細胞 / Stellate細胞 / HCV-O / フレームシフト / 遺伝子増幅 / ディファレンシャルディスプレイ法 / HCV感染肝細胞 / HCV遺伝子 / 持続感染培養細胞 / 細胞指向性 / Diffeerential display / マイナス鎖RNA / HCV分子種 / HCV感染細胞 / HCV増殖系 / C型肝炎ウィルス / 中和エピトープ / cDNAクローニング / ウイルス遺伝子 / 慢性肝炎 / 持続感染 / 免疫監視機構 / エンベロープ蛋白質 / HCV感染培養細胞 / 体液性免疫応答 … More Except Principal Investigator HCV / NS5B / long RT-PCR / tri-hybrid system / ribosome / RNA replication / maltose binding protein / the 3' X / RNA複製 / PTB / MBP / リボゾーム / 3ハイブリッドシステム / 3'X / cell culture / infectious clone / Hepatitis Cvirus / long RTPCR / long RT PCR / 培養細胞 / 感染性クローン / C型肝炎ウイルス / 疫学調査 / リーシュマニア / 疫学 / 風土病 / 創薬シーズ / 遺伝子解析 / リーシュマニア症 / マラリア Less

Research on the mechanism of hepatocarcinogenesis by long-term replication of hepatitis virusPrincipal Investigator
- Principal Investigator
  
  Kato Nobuyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Okayama University
Antiviral mechanism of new endoperoxide compounds showing antimalarial activityPrincipal Investigator
- Principal Investigator
  
  Kato Nobuyuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Okayama University
Research on host factors which are involved in the progression of HCV-induced hepatic deseasesPrincipal Investigator
- Principal Investigator
  
  KATO NOBUYUKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Okayama University
Joint Cooperative Research for Endemic Diseases Control in Ghana
- Principal Investigator
  
  KIM Hye-Sook
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Okayama University
Development ofthe infection and proliferation systemof the 1bgenotype HCV based on the new ideaPrincipal Investigator
- Principal Investigator
  
  KATO Nobuyuki
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Okayama University
C型肝炎ウイルス感染による肝線維化の分子生物学的解析Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Okayama University
C型肝炎ウイルス蛋白質の転写調節能とゲノム不安定化能に関する研究Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
C型肝炎ウイルスゲノムにコードされる新規蛋白質の探索Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Okayama University
C型肝炎ウイルス蛋白質の発現調節能と遺伝子不安定化能に関する研究Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
C型肝炎ウイルスコア蛋白質の転写制御能に関する研究Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
Role of the 3' terminal structure of hepatitis C virus genome in the viral life cycle
- Principal Investigator
  
  TANAKA Torahiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Cancer Center Research Institute
C型肝炎ウイルスの細胞指向性の解析Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
Cell Cuiture System Supporting Hepatitis C Virus Replication by Using Infections RNA
- Principal Investigator
  
  SUGIYAMA Kazuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Cancer Center Research Institute
C型肝炎ウィルスの増殖により発現制御されるがん化要因遺伝子の探索Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
肝細胞がん化に関するC型肝炎ウイルスの複製機構の解析Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
C型肝炎ウイルスの持続感染細胞株の樹立とウイルスの中和エピトープの解析Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
C型肝炎ウイルスのエンベロープ蛋白質内に存在する超可変領域に対する体液性免疫応答Principal Investigator
- Principal Investigator
  
  加藤宣之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
Analysis of Variation of Hepatitis C Viral Genome.Principal Investigator
- Principal Investigator
  
  KATO Nobuyuki
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  National Cancer Center
ヒト内在性レトロウィルス遺伝子により転写制御される細胞遺伝子の解析Principal Investigator
- Principal Investigator
  
  加藤宜之
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2019 2018 2017 2016 2015 2014 2013 2012 2005 Other

All Journal Article Presentation

[Journal Article] High‐level expression of STING restricts susceptibility to HBV by mediating type III IFN induction.2019
- Author(s)
  Dansako H, Imai H, Ueda Y, Satoh S, Shimotohno K, Kato N.
- Journal Title
  
  FASEB BioAdvances
  
  Volume: 1 Pages: 67-80
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05196
[Journal Article] Acidic polysaccharides isolated from marine algae inhibit the early step of viral infection.2019
- Author(s)
  Ueno M, Nogawa M, Siddiqui R, Watashi K, Wakita T, Kato N, Ikeda M, Okimura T, Isaka S, Oda T, Ariumi Y.
- Journal Title
  
  Int J Biol Macromol
  
  Volume: 124 Pages: 282-290
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05196
[Journal Article] Ribavirin-induced down-regulation of CCAAT/enhancer-binding protein α leads to suppression of lipogenesis2018
- Author(s)
  Satoh Shinya、Onomura Daichi、Ueda Youki、Dansako Hiromichi、Honda Masao、Kaneko Shuichi、Kato Nobuyuki
- Journal Title
  
  Biochemical Journal
  
  Volume: 476 Issue: 1 Pages: 137-149
- DOI
  10.1042/bcj20180680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07972, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-18K15169
[Journal Article] Regulation of interferon signaling and HCV-RNA replication by extracellular matrix.2018
- Author(s)
  Kuwashiro T, Iwane S, Jinghe X, Matsuhashi S, Eguchi Y, Anzai K, Fujimoto K, Mizuta T, Sakamoto N, Ikeda M, Kato N, Ozaki I.
- Journal Title
  
  Int J Mol Med
  
  Volume: 42 Pages: 957-965
- DOI
  10.3892/ijmm.2018.3693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-16H05282
[Journal Article] ULBP1 is induced by hepatitis C virus infection and is the target of the NK cell-mediated innate immune response in human hepatocytes2018
- Author(s)
  Dansako Hiromichi、Imai Hirotaka、Ueda Youki、Satoh Shinya、Wakita Takaji、Kato Nobuyuki
- Journal Title
  
  FEBS Open Bio
  
  Volume: 8 Issue: 3 Pages: 361-371
- DOI
  10.1002/2211-5463.12373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-15K08498
[Journal Article] Dual effects of the Nrf2 inhibitor for inhibition of hepatitis C virus and hepatic cancer cells.2018
- Author(s)
  Murakami Y, Sugiyama K, Ebinuma H, Nakamoto N, Ojiro K, Chu PS, Taniki N, Saito Y, Teratani T, Koda Y, Suzuki T, Saito K, Fukasawa M, Ikeda M, Kato N, Kanai T, Saito H.
- Journal Title
  
  BMC Cancer.
  
  Volume: 3 Issue: 1 Pages: 680-680
- DOI
  10.1186/s12885-018-4588-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-17H03592
[Journal Article] Multiple antiviral activities of the antimalarial and anti-hepatitis C drug candidates N-89 and N-2512018
- Author(s)
  Ueda Youki、Gu Weilin、Dansako Hiromichi、Kim Hye-Sook、Yoshizaki Sayaka、Okumura Nobuaki、Ishikawa Tomohiro、Nishitsuji Hironori、Kato Fumihiro、Hishiki Takayuki、Satoh Shinya、Ishii Koji、Masuda Michiaki、Shimotohno Kunitada、Ikeda Masanori、Kato Nobuyuki
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 15 Pages: 1-6
- DOI
  10.1016/j.bbrep.2018.05.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08870, KAKENHI-PROJECT-18K15169, KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-16K08825, KAKENHI-PROJECT-18K07086
[Journal Article] Daunorubicin, a topoisomerase II poison, suppresses viral production of hepatitis B virus by inducing cGAS-dependent innate immune response2018
- Author(s)
  Imai Hirotaka、Dansako Hiromichi、Ueda Youki、Satoh Shinya、Kato Nobuyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 504 Issue: 4 Pages: 672-678
- DOI
  10.1016/j.bbrc.2018.08.195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15169, KAKENHI-PROJECT-16H05196
[Journal Article] Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate-activated protein kinase-related kinases and retinoid X receptor α.2017
- Author(s)
  S Satoh, K Mori, D Onomura, Y Ueda, H Dansako, M Honda, S Kaneko, M Ikeda, N Kato.
- Journal Title
  
  Hepatol Commun
  
  Volume: 1 Issue: 6 Pages: 550-563
- DOI
  10.1002/hep4.1065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H05196
[Journal Article] Suppression of oncolytic adenovirus-mediated hepatotoxicity by liver-specific inhibition of NF-κB.2017
- Author(s)
  Machitani M., Sakurai F., Wakabayashi K., Nakatani K., Tachibana M.,　Kato N., Fujiwara T., Mizuguchi H.
- Journal Title
  
  Mol. Ther. Oncolysis.
  
  Volume: 7 Pages: 76-85
- DOI
  10.1016/j.omto.2017.10.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H00863, KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-16J05920
[Journal Article] Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems.2017
- Author(s)
  Ueda Y, Dansako H, Sato S, Kim HS, Wataya Y, Doi H, Ikeda M, Kato N.
- Journal Title
  
  Virus Res
  
  Volume: 235 Pages: 37-48
- DOI
  10.1016/j.virusres.2017.03.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-15K15142
[Journal Article] Effects of resistance-associated NS5A mutations in hepatitis C virus on viral production and susceptibility to antiviral reagents.2016
- Author(s)
  Nitta S, Asahina Y, Matsuda M, Yamada N, Sugiyama R, Masaki T, Suzuki R, Kato N, Watanabe M, Wakita T, Kato T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 34652-34652
- DOI
  10.1038/srep34652
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-16H05285, KAKENHI-PROJECT-15K15142, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-15K19316, KAKENHI-PROJECT-15K09035, KAKENHI-PROJECT-26860309
[Journal Article] Molecular mechanism underlying the suppression of CPB2 expression caused by persistent hepatitis C virus RNA replication.2016
- Author(s)
  Sejima H, Satoh S, Dansako H, Honda M, Kaneko S, Ikeda M, Kato N.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 70 Pages: 75-88
- NAID
  120005749825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15142
[Journal Article] Molecular mechanism underlying the suppression of CPB2 expression caused by persistent hepatitis C virus RNA replication.2016
- Author(s)
  Sejima H, Satoh S, Dansako H,Honda M, Kaneko S, Ikeda M, Kato N.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 70 Pages: 75-88
- NAID
  120005749825
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293110
[Journal Article] Rab13 is involved in the entry step of hepatitis C virus infection.2016
- Author(s)
  Takeda M, Ikeda M, Satoh S, Dansako H, Wakita T, Kato N.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 70 Pages: 111-118
- NAID
  120005749829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05196
[Journal Article] Molecular mechanism underlying the suppression of CPB2 expression caused by persistent hepatitis C virus RNA replication.2016
- Author(s)
  Sejima H, Satoh S, Dansako H, Honda M, Kaneko S, Ikeda M, Kato N.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 70 Pages: 75-88
- NAID
  120005749825
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05196
[Journal Article] Rab13 is involved in the entry step of hepatitis C virus infection.2016
- Author(s)
  Takeda M, Ikeda M, Satoh S, Dansako H, Wakita T, Kato N.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 70 Pages: 111-118
- NAID
  120005749829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293110
[Journal Article] Establishment of hepatitis C virus RNA-replicating cell lines possessing ribavirin-resistant phenotypes2015
- Author(s)
  Satoh S, Mori K, Ueda Y, Sejima H, Dansako H, Ikeda M, Kato N.
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 2 Pages: e0118313-e0118313
- DOI
  10.1371/journal.pone.0118313
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J02962, KAKENHI-PROJECT-25293110, KAKENHI-PROJECT-15K08498
[Journal Article] Control of HCV Replication with iMIRs, a Novel Anti-RNAi Agent2015
- Author(s)
  Saori Itami, Yutaka Eguchi, Takayuki Mizutani, Eriko Aoki, Tadaaki Ohgi, Masahiko Kuroda, Takahiro Ochiya, Nobuyuki Kato, Hiroshi I Suzuki, Norifumi Kawada and Yoshiki Murakami
- Journal Title
  
  Molecular Therapy Nucleic Acids
  
  Volume: 4 Pages: e219-e219
- DOI
  10.1038/mtna.2014.71
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25640090, KAKENHI-PROJECT-15K08649, KAKENHI-PROJECT-15K15142, KAKENHI-PROJECT-25293110
[Journal Article] Involvement of FKBP6 in hepatitis C virus replication.2015
- Author(s)
  Kasai H, Kawakami Y, Yokoe H, Yoshimura K, Matsuda M, Yasumoto J, Maekawa S, Yamashita A, Tanaka T, Ikeda M, Kato N, Okamoto T, Matsuura Y, Sakamoto N, Enomoto N, Takeda S, Fujii H, Tsubuki M, Kusunoki M, Moriishi K.
- Journal Title
  
  Scientific reports
  
  Volume: 5 Issue: 1 Pages: 16699-16699
- DOI
  10.1038/srep16699
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493, KAKENHI-PROJECT-15K15142, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-25460985, KAKENHI-PROJECT-25293110, KAKENHI-PROJECT-25713023
[Journal Article] Annexin A1 negatively regulates viral RNA replication of hepatitis C virus.2015
- Author(s)
  Hiramoto H, Dansako H, Takeda M, Satoh S, Wakita T, Ikeda M, Kato N.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 69 Pages: 71-78
- NAID
  120005595787
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293110
[Journal Article] Rab18 is required for viral assembly of hepatitis C virus through trafficking of the core protein to lipid droplets.2014
- Author(s)
  Dansako H, Hiramoto H, Ikeda M, Wakita T, Kato N.
- Journal Title
  
  Virology
  
  Volume: 462-463 Pages: 166-74
- DOI
  10.1016/j.virol.2014.05.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590544, KAKENHI-PROJECT-25293110
[Journal Article] Synthesis and inhibitory activity on hepatitis C virus RNA replication of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propyl)aniline analogs2014
- Author(s)
  Matsuno K, Ueda Y, Fukuda M, Onoda K, Waki M, Ikeda M, Kato N, Miyachi H.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Issue: 17 Pages: 4276-80
- DOI
  10.1016/j.bmcl.2014.07.019
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J02962, KAKENHI-PROJECT-25293110
[Journal Article] IPS-1 is essential for type III interferon production by hepatocytes and dendritic cells in response to hepatitis C virus infection.2014
- Author(s)
  Okamoto M, Oshiumi H, Azuma M, Kato N, Matsumoto M, Seya T.
- Journal Title
  
  J. Immunol.
  
  Volume: 192 Pages: 2770-2777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293110
[Journal Article] Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization.2014
- Author(s)
  Hara Y, Yanatori I, Ikeda M, Kiyokage E, Nishina S, Tomiyama Y, Toida K, Kishi F, Kato N, Imamura M, Chayama K, Hino K.
- Journal Title
  
  Am J Pathol. 2014
  
  Volume: 184 Issue: 11 Pages: 3026-39
- DOI
  10.1016/j.ajpath.2014.07.024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659377, KAKENHI-PROJECT-25670374, KAKENHI-PROJECT-26293179, KAKENHI-PROJECT-26670383, KAKENHI-PROJECT-25293110
[Journal Article] Genetic Characterization of Hepatitis C Virus in Long-Term RNA Replication Using Li23 Cell Culture Systems.2014
- Author(s)
  Kato N, Sejima H, Ueda Y, Mori K, Satoh S, Dansako H, Ikeda M.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 3 Pages: e91156-e91156
- DOI
  10.1371/journal.pone.0091156
- NAID
  120005697276
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590544, KAKENHI-PROJECT-25293110
[Journal Article] Anti-HCV activity of the Chinese medicinal fungus Cordyceps militaris.2014
- Author(s)
  Ueda Y, Mori K, Satoh S, Dansako H, Ikeda M, Kato N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 447 Issue: 2 Pages: 341-5
- DOI
  10.1016/j.bbrc.2014.03.150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590544, KAKENHI-PROJECT-25293110
[Journal Article] Once-daily simeprevir in combination with pegylated-interferon and ribavirin: a new horizon in the era of direct-acting antiviral agent therapy for chronic hepatitis C.2014
- Author(s)
  Maekawa S, Enomoto N
- Journal Title
  
  J Gastroenterol.
  
  Volume: 49(1) Issue: 12 Pages: 163-164
- DOI
  10.1371/journal.pone.0082299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390195, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590965, KAKENHI-PROJECT-24659204, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-25460985, KAKENHI-PROJECT-25293110
[Journal Article] Synthesis of 3',4'-difluoro-3'-deoxyribonucleosides and its evaluation of the biological activities: Discovery of a novel type of anti-HCV agent 3',4'-difluorocordycepin2014
- Author(s)
  Shimada H, Haraguchi K, Hotta K, Miyaike T, Kitagawa Y, Tanaka H, Kaneda R, Abe H, Shuto S, Mori K, Ueda Y, Kato N, Snoeck R, Andrei G, Balzarini J.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 22 Issue: 21 Pages: 6174-82
- DOI
  10.1016/j.bmc.2014.08.024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J02962, KAKENHI-PROJECT-24390023, KAKENHI-PROJECT-25282240, KAKENHI-PROJECT-25293110
[Journal Article] Alternative endocytosis pathway for productive entry of hepatitis C virus.2014
- Author(s)
  Matsuda M, Suzuki R, Kataoka C, Watashi K, Aizaki H, Kato N, Matsuura Y, Suzuki T, Wakita T
- Journal Title
  
  J Gen Virol.
  
  Volume: 95(Pt 12) Issue: 12 Pages: 2658-67
- DOI
  10.1099/vir.0.068528-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390111, KAKENHI-PROJECT-24591001, KAKENHI-PROJECT-25860832, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-26670224, KAKENHI-PROJECT-25293110, KAKENHI-PROJECT-25293134
[Journal Article] New preclinical antimalarial drugs potently inhibit hepatitis C virus genotype 1b RNA replication2013
- Author(s)
  Ueda Y, et al.
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 8 Pages: e72519-e72519
- DOI
  10.1371/journal.pone.0072519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02962, KAKENHI-PROJECT-23590544, KAKENHI-PROJECT-24790216, KAKENHI-PROJECT-25293110
[Journal Article] Suppressive Effect of the Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid (SAHA), on Hepatitis C Virus Replication via Epigenetic Changes in Host Cells2013
- Author(s)
  Sato, A., Saito, Y., Sugiyama, K., Sakasegawa, N., Muramatsu, T., Fukuda, S., Yoneya, M., Kimura, M., Ebinuma, H., Hibi, T., Saito, H
- Journal Title
  
  J Cell Biochem
  
  Volume: 印刷中 Issue: 9 Pages: 1987-1996
- DOI
  10.1002/jcb.24541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23680090, KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-25293110
[Journal Article] Ca(2+) /S100 proteins regulate HCV virus NS5A-FKBP8/FKBP38 interaction and HCV virus RNA replication2013
- Author(s)
  Tani J, Shimamoto S, Mori K, Kato N, Moriishi K, Matsuura Y, Tokumitsu H, Tsuchiya M, Fujimoto T, Kato K, Miyoshi H, Masaki T, Kobayashi R.
- Journal Title
  
  Liver Int
  
  Volume: 33 Issue: 7 Pages: 1008-1018
- DOI
  10.1111/liv.12151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659204, KAKENHI-PROJECT-25293110
[Journal Article] New preclinical antimalarial drugs potently inhibit hepatitis C virus genotype 1b RNA replication2013
- Author(s)
  Ueda, Y., Takeda, M., Mori, K., Dansako, H., Wakita, T., Kim, H.-S., Sato, A., Wataya, Y., Ikeda, M. and Kato, N.
- Journal Title
  
  PLosOne,
  
  Volume: 8 Pages: 1-11
- NAID
  120005697275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25305008
[Journal Article] Hepatitis C virus NS4B targets lipid droplets through hydrophobic residues in the amphipathic helices2013
- Author(s)
  Tanaka T et al.
- Journal Title
  
  J Lipid Res.
  
  Volume: 54(4) Issue: 4 Pages: 881-892
- DOI
  10.1194/jlr.m026443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590420, KAKENHI-PROJECT-25293110
[Journal Article] Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity.2013
- Author(s)
  Ding Q, Cao X, Lu J, Huang B, Liu YJ, Kato N, Shu HB, Zhong J.
- Journal Title
  
  J Hepatol.
  
  Volume: 59 Issue: 1 Pages: 52-58
- DOI
  10.1016/j.jhep.2013.03.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293110
[Journal Article] Direct targeting of proteins to lipid droplets demonstrated by time-lapse live cell imaging.2013
- Author(s)
  Tanaka T, Kuroda K, Ikeda M, Kato N, Shimizu K, Makishima M.
- Journal Title
  
  J Biosci. Bioeng.
  
  Volume: 116 Pages: 620-623
- NAID
  110009685215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293110
[Journal Article] Adenosine kinase is a key determinant for the anti-HCV activity of ribavirin2013
- Author(s)
  Mori K, Hiraoka O, Ikeda M, Ariumi Y, Hiramoto A, Wataya Y, Kato N
- Journal Title
  
  Hepatology
  
  Volume: 58 Issue: 4 Pages: 1236-44
- DOI
  10.1002/hep.26421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590544, KAKENHI-PROJECT-23590545, KAKENHI-PROJECT-25293110
[Journal Article] Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells.2013
- Author(s)
  Dansako H, Yamane D, Welsch C, McGivern DR, Hu F, Kato N, and Lemon SM.
- Journal Title
  
  PLoS Pathogens
  
  Volume: 9 Issue: 5 Pages: e1003345-e1003345
- DOI
  10.1371/journal.ppat.1003345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293110
[Journal Article] Unfolded protein response pathways regulate Hepatitis C virus replication via modulation of autophagy.2013
- Author(s)
  Shinohara Y, Imajo K, Yoneda M, Tomeno W, Ogawa Y, Kirikoshi H, Funakoshi K, Ikeda M, Kato N, Nakajima A, Saito S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 432 Issue: 2 Pages: 326-332
- DOI
  10.1016/j.bbrc.2013.01.103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293110
[Journal Article] Hepatic triglyceride lipaseplays an essential role in changing the lipid metabolism in genotype 1b hepatitis C virus replicon cells and hepatitis C patients2013
- Author(s)
  ShinoharaY, Imajo K, Yoned M, Tomeno W, Ogawa Y, Fujita K, Kirikoshi H, Takahashi J, Funakoshi K, Ikeda M, Kato N, Nakajima A, Saito S
- Journal Title
  
  Hepatol Res
  
  Volume: 43 Issue: 11 Pages: 1190-1198
- DOI
  10.1111/hepr.12072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590743, KAKENHI-PROJECT-25293110
[Journal Article] Peroxisome proliferator-activated receptor delta antagonists inhibit hepatitis C virus RNA replication.2013
- Author(s)
  Ban S, Ueda Y, Ohashi M, Matsuno K, Ikeda M, Kato N, and Miyachi H.
- Journal Title
  
  Bioorg. Med. Chem. Letters
  
  Volume: 23 Pages: 4774-4778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293110
[Journal Article] PML tumor suppressor protein is required for HCV production2013
- Author(s)
  Kuroki M, Ariumi Y, Hijikata M, Ikeda M, Dansako H, Wakita T, Shimotohno K, Kato N
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 430 Pages: 592-597
- NAID
  120005311976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659207
[Journal Article] Identification of host genes showing differential expression profiles with cell-based long-term replication of hepatitis C virus RNA2012
- Author(s)
  Sejima H, Mori K, Ariumi Y, Ikeda M, Kato N
- Journal Title
  
  Virus Res
  
  Volume: 167(1) Pages: 74-85
- NAID
  120006331940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659207
[Journal Article] Genetic variation and dynamics of hepatitis C virus replicons in long-term cell culture.2005
- Author(s)
  Nobuyuki Kato他
- Journal Title
  
  J.Gen.Virol. 86(3)
  
  Pages: 645-656
- Data Source
  KAKENHI-PROJECT-16659120
[Journal Article] Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system2005
- Author(s)
  Masanori Ikeda, Nobuyuki Kato他
- Journal Title
  
  Biochemical and Biophysical Research Communications 329(4)
  
  Pages: 1350-1359
- Data Source
  KAKENHI-PROJECT-16659120
[Presentation] Screening of the new host factors necessary for HBV proliferation using plural human cell lines2018
- Author(s)
  Youki Ueda, Hiromichi Dansako, Shinya Satoh, Kunitada Shimotohno, Nobuyuki Kato
- Organizer
  第66回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Mechanism of GPAM suppression by Anti-HCV drug ribavirin2018
- Author(s)
  Daichi Onomura, Shinya Satoh, Youki Ueda, Hiromichi Dansako, Nobuyuki Kato
- Organizer
  第66回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Highly expression of STING restricts HBV infection by mediating the induction of type III interferon in human immortalized hepatocyte NKNT-32018
- Author(s)
  Hiromichi Dansako, Hirotaka Imai, Youki Ueda, Shinya Satoh, Kunitada Shimotohno, Nobuyuki Kato
- Organizer
  第66回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] B型肝炎ウイルス感染ヒト不死化肝NKNT-3細胞由来のエクソソーム内タンパク質の解析2018
- Author(s)
  團迫浩方、今井大誉、上田優輝、佐藤伸哉、加藤宣之
- Organizer
  第５回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Drug screening for suppression of lipogenesis through downregulation of C/EBPα2018
- Author(s)
  Shinya Satoh, Daichi Onomura, Koichi Watashi, Youki Ueda, Hiromichi Dansako, Masao Honda,, Shuichi Kaneko, Nobuyuki Kato
- Organizer
  第66回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] 抗HCV剤としての抗精神病薬ペロスピロンの可能性について2018
- Author(s)
  武田緑、谷口智香、前園夏絵、脇田隆字、加藤宣之、池田正徳
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Analysis of the new host factors necessary for susceptibility to HBV using plural human cell lines2018
- Author(s)
  Youki Ueda, Hiromichi Dansako, Shinya Satoh, Kunitada Shimotohno, Nobuyuki Kato
- Organizer
  2018 International Meeting on Molecular Biology of Hepatitis B Virus
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] 抗マラリア及び抗HCV薬候補N-89とN-251が有する幅広い抗ウイルス活性2018
- Author(s)
  上田優輝, 谷イ琳, 團迫浩方, 金惠淑, 吉崎佐矢香, 奥村暢章, 石川知弘, 西辻裕紀, 加藤文博, 日紫喜隆行, 佐藤伸哉, 石井孝司, 増田道明, 下遠野邦忠, 池田正徳, 加藤宣之
- Organizer
  第28回抗ウイルス療法学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Perospirone, an antipsychotics, exhibits anti-hepatitis C virus activity2018
- Author(s)
  Midori Takeda, Tomoka Taniguchi, Matsue Maezono, Takaji Wakita, Nobuyuki Kato, Masanori Ikeda
- Organizer
  第66回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Topoisomerase II inhibitor triggers cyclic GMP-AMP synthase-dependent innate immune response in human immortalized hepatocyte NKNT-32018
- Author(s)
  Hirotaka Imai, Hiromichi Dansako, Youki Ueda, Shinya Satoh, Nobuyuki Kato
- Organizer
  第66回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Analysis of host and viral factors contributing to resistant acquisition for the preclinical anti-HCV drugs, N-89 and N-2512018
- Author(s)
  Weilin Gu, Youki Ueda, Shinya Satoh, Hiromichi Dansako, Nobuyuki Kato
- Organizer
  第66回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Suppression of oncolytic adenovirus-mediated hepatotoxicity by liver-specific inhibition of NF-κB2018
- Author(s)
  Mitsuhiro Machitani, Fuminori Sakurai, Keisaku Wakabayashi, Masashi Tachibana, Nobuyuki Kato, Toshiyoshi Fujiwara, Hiroyuki Mizuguchi
- Organizer
  第24回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Downregulation of C/EBPα by anti-HCV drug ribavirin leads to the suppression of triglyceride synthesis pathway2017
- Author(s)
  Shinya Satoh, Daichi Onomura, Youki Ueda, Hiromichi Dansako, Masao Honda, Shuichi Kaneko, Nobuyuki Kato
- Organizer
  第65回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Identification of new amino acid substitutions contributing to DAA-resistance, using HCV reporter assay systems2017
- Author(s)
  Youki Ueda, Hiromichi Dansako, Shinya Satoh, Masanori Ikeda, Nobuyuki Kato
- Organizer
  第65回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] クロファラビンはドラッグリポジショニングにより見いだされた抗HBV活性と抗HCV活性を有する治療剤候補である2017
- Author(s)
  武田緑、加藤　宣之、池田　正徳
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Development of human hepatoma cell line, Li23-derived cells possessing high susceptibility to HBV2017
- Author(s)
  Youki Ueda, Hiromichi Dansako, Shinya Satoh, Kunitada Shimotohno, Nobuyuki Kato
- Organizer
  2017 International Meeting on Molecular Biology of Hepatitis B Virus
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Resistant acquisition mechanism for anti-HCV drug candidates, N-89 and its derivative N-2512017
- Author(s)
  Weilin Gu, Youki Ueda, Shinya Satoh, Hiromichi Dansako, Nobuyuki Kato
- Organizer
  第65回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Development of HBV infection system using human immortalized hepatocyte NKNT-3 cells2017
- Author(s)
  Hiromichi Dansako, Hirotaka Imai, Youki Ueda, Shinya Satoh, Kunitada Shimotohno, Nobuyuki Kato
- Organizer
  第65回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] HCVポリメラーゼ/プロテアーゼ二重阻害活性を有するフラーレン誘導体の細胞内HCV複製阻害及び酸化ストレス抑制効果2017
- Author(s)
  片岡　裕樹、上田　優輝、髙橋　恭子、中村　成夫、大江　知之、加藤　宣之、増野　匡彦
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] 交感神経遮断薬であるグアンファシンは抗HCV活性を示す2017
- Author(s)
  武田　緑、前園　夏絵、上高原　美奈、脇田　隆字、加藤　宣之、池田　正徳
- Organizer
  第65回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Both host and viral factors contribute to the resistance to preclinical anti-HCV drugs, N-89 and N-251.2016
- Author(s)
  Gu W, Ueda Y, Dansako H, Satoh S, Kato N.
- Organizer
  The 64th Annual Meeting of The Japanese Society for Virology
- Place of Presentation
  札幌コンベンションセンター、札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] DAA製剤によるHCV治療におけるN-89/N-251の有用性とそれらの作用機序の解析2016
- Author(s)
  上田優輝、團迫浩方、佐藤伸哉、池田正徳、加藤宣之
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋市立大学、名古屋
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] DNA-PKcs and Rad18 are required for HCV replication.2016
- Author(s)
  Ariumi Y, Tateishi S, Wakita T, Kato N.
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  国際会議場、京都
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Genetic characterization of HCVs obtained from HCV-RNA-replicating cells possessing a DAA-, N-89-, or N-251-resistant phenotype.2016
- Author(s)
  Ueda　Y, Dansako H, Satoh S, Ikeda M, Kato N.
- Organizer
  The 64th Annual Meeting of The Japanese Society for Virology
- Place of Presentation
  札幌コンベンションセンター、札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] DAA製剤によるHCV治療におけるN-89/N-251の有用性とそれらの作用機序の解析2016
- Author(s)
  上田優輝、團迫浩方、佐藤伸哉、池田正徳、加藤宣之
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋市立大学、名古屋
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K15142
[Presentation] HBVとHCVに対する抗ウイルス剤の探索2016
- Author(s)
  武田緑、團迫浩方、馬場昌範、加藤宣之、池田正徳
- Organizer
  第53回日本ウイルス学会九州支部会
- Place of Presentation
  宮崎市民プラザ、宮崎
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-16H05196
[Presentation] Both host and viral factors contribute to the resistance to preclinical anti-HCV drugs, N-89 and N-251.2016
- Author(s)
  Gu W, Ueda Y, Dansako H, Satoh S, Kato N.
- Organizer
  The 64th Annual Meeting of The Japanese Society for Virology
- Place of Presentation
  札幌コンベンションセンター、札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K15142
[Presentation] Genetic characterization of HCVs obtained from HCV-RNA-replicating cells possessing a DAA-, N-89-, or N-251-resistant phenotype.2016
- Author(s)
  Ueda　Y, Dansako H, Satoh S, Ikeda M, Kato N.
- Organizer
  The 64th Annual Meeting of The Japanese Society for Virology
- Place of Presentation
  札幌コンベンションセンター、札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K15142
[Presentation] Antimalarial preclinical drugs, N-89 and N-251, overcome various DAAs-resistant HCVs.2015
- Author(s)
  Youki Ueda, Hiromichi Dansako, Shinya Satoh, Hye-Sook Kim, Hiroyuki Doi, Yusuke Wataya, Masanori Ikeda, Nobuyuki Kato.
- Organizer
  22nd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Strasbourg, France
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15142
[Presentation] DNA repair protein Rad18 is required for HCV replication.2015
- Author(s)
  Yasuo Ariumi, Mariko Yasuda-Inoue, Satoshi Tateishi, Takaji Wakita, Nobuyuki Kato.
- Organizer
  第6３回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] New function of anti-HCV drug ribavirin: suppressive effect in hepatic lipogenesis.2015
- Author(s)
  Shinya Satoh, Youki Ueda, Hiromichi Dansako, Masao Honda, Shuichi Kaneko, Masanori Ikeda, Nobuyuki Kato.
- Organizer
  第6３回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Antimalarial preclinical drugs, N-89 and N-251, overcome various DAAs-resistant HCVs.2015
- Author(s)
  Youki Ueda, Hiromichi Dansako, Shinya Satoh, Hye-Sook Kim, Hiroyuki Doi, Yusuke Wataya, Masanori Ikeda, Nobuyuki Kato.
- Organizer
  第6３回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K15142
[Presentation] C型肝炎ウイルスの阻害剤探索を目的にしたスクリーニングシステムの開発2015
- Author(s)
  武田緑、池田正徳、佐藤伸哉、團迫浩方、加藤宣之.
- Organizer
  第38回日本分子生物学会年会第88回に本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド、神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Function and transcriptional regulation mechanism of CPB2 gene downregulated by 　persistent HCV RNA replication.2015
- Author(s)
  瀬島寛恵、佐藤伸哉、團迫浩方、上田優輝、本多政夫、金子周一、池田正徳、加藤宣之
- Organizer
  第6３回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Antimalarial preclinical drugs, N-89 and N-251, overcome various DAAs-resistant HCVs.2015
- Author(s)
  Youki Ueda, Hiromichi Dansako, Shinya Satoh, Hye-Sook Kim, Hiroyuki Doi, Yusuke Wataya, Masanori Ikeda, Nobuyuki Kato.
- Organizer
  第6３回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Improved ExoQuick protocol for the preparation of exosomes released from human heptoma cells.2015
- Author(s)
  Hiroki Hiramoto, Hiromichi Dansako, Youki Ueda, Shinya Satoh, Masanori Ikeda, Nobuyuki Kato.
- Organizer
  第6３回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] C型肝炎ウイルスのゲノム複製が2年間にわたることで発現レベルが変動したマイクロRNAの同定.2013
- Author(s)
  瀬島　寛恵、森　京子、佐藤　伸哉、團迫　浩方、池田　正徳、加藤　宣之.
- Organizer
  第６１回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Identification of two microRNAs showing decreased expression in cell-based HCV RNA replication for 2 years.2013
- Author(s)
  Hiroe Sejima, Kyoko Mori, Shinya Satoh, Hiromichi Dansako, Masanori Ikeda, Nobuyuki Kato.
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Melbourne Convention and Exhibition Centre (Australia)
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Rab18はC型肝炎ウイルスの感染性粒子形成に重要な宿主因子である.2013
- Author(s)
  團迫　浩方、平本　洸貴、池田　正徳、脇田　隆字、加藤　宣之.
- Organizer
  第６１回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Identification of microRNAs showing differential expression profiles in cell-based HCV RNA replication for 2 years.2013
- Author(s)
  瀬島寛恵、森　京子、佐藤　伸哉、團迫　浩方、池田　正徳、加藤　宣之.
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Rab18 is required for viral assembly of hepatitis C virus through the association with core protein around lipid droplet.2013
- Author(s)
  Hiromichi Dansako, Hiroki Hiramoto, Masanori Ikeda, Takaji Wakita, Nobuyuki Kato.
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Melbourne Convention and Exhibition Centre (Australia)
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Ｃ型肝炎ウイルスNS4Bの両親媒性へリックス内疎水性残基がウイルス複製に果たす役割.2013
- Author(s)
  田中　寅彦、山本　真民、黒田　和道、脇田　隆字、池田　正徳、加藤　宣之、槇島　誠.
- Organizer
  第６１回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] C型肝炎ウイルスのライフサイクルにおける宿主因子annexin A1の役割.2013
- Author(s)
  平本　洸貴, 團迫　浩方, 瀬島　寛恵, 森　京子, 佐藤　伸哉, 池田　正徳, 脇田　隆字, 加藤　宣之.
- Organizer
  第６１回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] 長期にわたるC型肝炎ウイルスのゲノム複製によって発現レベルに変動を来した宿主遺伝子の同定2012
- Author(s)
  瀬島寛恵、森京子、有海康雄、池田正徳、加藤宣之
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24659207
[Presentation] Annexin A1 negatively regulates HCV RNA replication
- Author(s)
  Hiramoto H, Dansako H, Takeda M, Satoh S, Wakita T, Ikeda M, Kato N
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff, Canada
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] 長期にわたるHCV-RNA複製によるBASP1とCPB2遺伝子の発現低下の分子機構の解析
- Author(s)
  瀬島寛恵、佐藤伸哉、團迫浩方、池田正徳、加藤宣之
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Rab13 is an essential host factor for HCV entry
- Author(s)
  Tekeda M, Ikeda M, Satoh S, Dansako H, Wakita T, Kato N
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff, Canada
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] C型肝炎ウイルスRNAの長期細胞内複製によって発現低下した遺伝子の発現制御機構の解析
- Author(s)
  瀬島寛恵　佐藤伸哉　團迫浩方　池田正徳　加藤宣之
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] HCVライフサイクルにおける小胞輸送蛋白質Rab13の役割
- Author(s)
  武田緑、池田正徳、佐藤伸哉、團迫浩方、脇田隆字、加藤宣之
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] HCV-RNAの長期複製によって発現低下したBASP1とCPB2遺伝子の発現制御機構の解析
- Author(s)
  瀬島寛恵、佐藤伸哉、團迫浩方、池田正徳、加藤宣之
- Organizer
  第18回日本肝臓学会大会
- Place of Presentation
  神戸
- Year and Date
  2014-10-23 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Characterization of anti-HCV activity of N-251, a preclinical antimalarial drug, and its combination effect with DAA
- Author(s)
  Ueda Y, Kim HS, Dansako H, Satoh S, Ikeda M, Doi H, Wataya Y, Kato N
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff, Canada
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Analysis on transcriptional regulatory mechanisms of genes whose expressions were reduced during long-term intracellular HCV-RNA replication
- Author(s)
  Sejima H, Satoh S, Dansako H, Ikeda M, Kato N
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff, Canada
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] DDX21 RNA helicase restricts HCV infection
- Author(s)
  Ariumi Y, Kuroki M, Siddiqui R, Hijikata M, Ikeda M, Wakita T, Kato N
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff, Canada
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-25293110
[Presentation] Human hepatoma HuH-7 cell line-derived RSc cells show higher viral productivity in response to infection with HCV-JFH-1 than Huh7.5 cells.
- Author(s)
  Dansako H, Hiramoto H, Ikeda M, Wakita T, Kato N.
- Organizer
  21th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff, Canada
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-25293110

1. DANSAKO Hiromichi (80379841)

# of Collaborated Projects: 3 results

# of Collaborated Products: 47 results
2. IKEDA Masanori (30315767)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
3. SATOH Shinya (80333558)

# of Collaborated Projects: 2 results

# of Collaborated Products: 41 results
4. KIM Hye-Sook (70314664)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 秋山公祐 (30222540)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MORI Kyoko (10633604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. DOI Hiroyuki (20452568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUGIYAMA Kazuo (10242520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. TANAKA Torahiko (90171785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 水谷哲也 (70281681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 野崎昭人 (20335631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 上田優輝 (90756074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
13. SEJIMA Hiroe

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. KOKU Irin

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. ONOMURA Daichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. HIRAMOTO Hiroki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MURAKAMI Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. SUZUKI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. YAMASHITA Atsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. NISHINA Sohji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. HARA Yuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. HISHIKI Takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 金子周一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 斎藤英胤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 森石恆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 落谷孝広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 恵口豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 黒田雅彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 水口裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 葛西宏威

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 田中智久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 日野啓輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 斉藤聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 中島淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 桐越博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 脇田隆字

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
38. 前川伸哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 榎本信幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 寺谷俊昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KATO Nobuyuki 加藤 宣之

加藤 宣之 カトウ ノブユキ

加藤 宜之 カトウ ノブユキ

Research Projects

Research Products

Co-Researchers

Research on the mechanism of hepatocarcinogenesis by long-term replication of hepatitis virusPrincipal Investigator

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Antiviral mechanism of new endoperoxide compounds showing antimalarial activityPrincipal Investigator

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Research on host factors which are involved in the progression of HCV-induced hepatic deseasesPrincipal Investigator

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Joint Cooperative Research for Endemic Diseases Control in Ghana

Principal Investigator

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Development ofthe infection and proliferation systemof the 1bgenotype HCV based on the new ideaPrincipal Investigator

Principal Investigator

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C型肝炎ウイルス感染による肝線維化の分子生物学的解析Principal Investigator

Principal Investigator

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C型肝炎ウイルス蛋白質の転写調節能とゲノム不安定化能に関する研究Principal Investigator

Principal Investigator

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C型肝炎ウイルスゲノムにコードされる新規蛋白質の探索Principal Investigator

Principal Investigator

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Research Institution

C型肝炎ウイルス蛋白質の発現調節能と遺伝子不安定化能に関する研究Principal Investigator

Principal Investigator

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Review Section

Research Institution

C型肝炎ウイルスコア蛋白質の転写制御能に関する研究Principal Investigator

Principal Investigator

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Research Institution

Role of the 3' terminal structure of hepatitis C virus genome in the viral life cycle

Principal Investigator

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C型肝炎ウイルスの細胞指向性の解析Principal Investigator

Principal Investigator

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Research Institution

Cell Cuiture System Supporting Hepatitis C Virus Replication by Using Infections RNA

Principal Investigator

Project Period (FY)

KATO Nobuyuki 加藤宣之

加藤宣之カトウノブユキ

加藤宜之カトウノブユキ