Tsuji Mayumi 辻まゆみ

… Alternative Names

TSUJI Mayumi 辻まゆみ

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Researcher Number	40155544
Other IDs
Affiliation (Current)	2025: 昭和大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 昭和大学, 医学部, 教授 2019 – 2020: 昭和大学, 薬理科学研究センター, 教授
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Transformative Research Areas, Section (III) / Basic Section 52020:Neurology-related
Keywords	Principal Investigator EGCG / フェルラ酸 / 健康食品 / アルツハイマー型認知症 / クルクミン / ミリセチン / Aβ凝集抑制 / 神経細胞傷害 / 抗酸化作用 / 併用療法 / ポリフェノール / アミロイドβ / アルツハイマー症 … More Except Principal Investigator … More オリゴマー / 共凝集 / アミロイド / メタアグリゲート / 毒性 / アルツハイマー病 / アルツハイマー病 Less

[Amyloid and heteroamyloid] Formation of meta-aggregates and their toxicity in mixed dementia
- Principal Investigator
  
  小野賢二郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kanazawa University
Study on the toxic mechanism of high-molecular A-beta oligomers focusing on membrane damage
- Principal Investigator
  
  Ono Kenjiro
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kanazawa University
  Showa University
Search for health food ingredients to prevent the onset of Alzheimer's disease targeting inhibition of amyloid B toxicityPrincipal Investigator
- Principal Investigator
  
  TSUJI Mayumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Showa University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] The Curcumin Derivative GT863 Protects Cell Membranes in Cytotoxicity by Aβ Oligomers2023
- Author(s)
  Momma Yutaro、Tsuji Mayumi、Oguchi Tatsunori、Ohashi Hideaki、Nohara Tetsuhito、Ito Naohito、Yamamoto Ken、Nagata Miki、Kimura Atsushi Michael、Nakamura Shiro、Kiuchi Yuji、Ono Kenjiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 3089-3089
- DOI
  10.3390/ijms24043089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09918, KAKENHI-PROJECT-22K07514, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-20K11266, KAKENHI-PLANNED-23H03850
[Journal Article] Extracellular high molecular weight α-synuclein oligomers induce cell death by disrupting the plasma membrane2023
- Author(s)
  Ito Naohito、Tsuji Mayumi、Adachi Naoki、Nakamura Shiro、Sarkar Avijite Kumer、Ikenaka Kensuke、Aguirre Cesar、Kimura Atsushi Michael、Kiuchi Yuji、Mochizuki Hideki、Teplow David B.、Ono Kenjiro
- Journal Title
  
  npj Parkinson's Disease
  
  Volume: 9 Issue: 1 Pages: 139-139
- DOI
  10.1038/s41531-023-00583-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18255, KAKENHI-PROJECT-20K19685, KAKENHI-PROJECT-22K07514, KAKENHI-PROJECT-22K09918, KAKENHI-PROJECT-19K07965, KAKENHI-PLANNED-23H03850, KAKENHI-PROJECT-23K24212
[Journal Article] Structural Dynamics of Amyloid-β Protofibrils and Actions of Anti-Amyloid-β Antibodies as Observed by High-Speed Atomic Force Microscopy2023
- Author(s)
  Watanabe-Nakayama Takahiro、Tsuji Mayumi、Umeda Kenichi、Oguchi Tatsunori、Konno Hiroki、Noguchi-Shinohara Moeko、Kiuchi Yuji、Kodera Noriyuki、Teplow David B.、Ono Kenjiro
- Journal Title
  
  Nano Letters
  
  Volume: 23 Issue: 13 Pages: 6259-6268
- DOI
  10.1021/acs.nanolett.3c00187
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07514, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-21K04849, KAKENHI-PLANNED-23H03850, KAKENHI-PROJECT-20H00327
[Journal Article] Combined Treatment with Curcumin and Ferulic Acid Suppressed the Aβ-Induced Neurotoxicity More than Curcumin and Ferulic Acid Alone2022
- Author(s)
  Ohashi H, Tsuji M, Oguchi T, Momma Y, Nohara T, Ito N, Yamamoto K, Nagata M, Kimura AM, Kiuchi Y, Ono K.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 17 Pages: 9685-9685
- DOI
  10.3390/ijms23179685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-20K11266, KAKENHI-PROJECT-22K07514
[Journal Article] The effect of α-tocopherol, α- and γ-tocotrienols on amyloid-β aggregation and disaggregation in vitro2021
- Author(s)
  Ibrahim Nor Faeizah、Hamezah Hamizah Shahirah、Yanagisawa Daijiro、Tsuji Mayumi、Kiuchi Yuji、Ono Kenjiro、Tooyama Ikuo
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 28 Pages: 101131-101131
- DOI
  10.1016/j.bbrep.2021.101131
- NAID
  120007186916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Serum BDNF as a Potential Biomarker of Alzheimer's Disease: Verification Through Assessment of Serum, Cerebrospinal Fluid, and Medial Temporal Lobe Atrophy2021
- Author(s)
  Mori Yukiko、Tsuji Mayumi、Oguchi Tatsunori、Kasuga Kensaku、Kimura Atsushi、Futamura Akinori、Sugimoto Azusa、Kasai Hideyo、Kuroda Takeshi、Yano Satoshi、Hieda Sotaro、Kiuchi Yuji、Ikeuchi Takeshi、Ono Kenjiro
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 12 Pages: 653267-653267
- DOI
  10.3389/fneur.2021.653267
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-20K11266
[Journal Article] Myricetin prevents high molecular weight Aβ1-42 oligomer-induced neurotoxicity through antioxidant effects in cell membranes and mitochondria2021
- Author(s)
  Kimura Atsushi Michael、Tsuji Mayumi、Yasumoto Taro、Mori Yukiko、Oguchi Tatsunori、Tsuji Yuya、Umino Masakazu、Umino Asami、Nishikawa Toru、Nakamura Shiro、Inoue Tomio、Kiuchi Yuji、Yamada Masahito、Teplow David B.、Ono Kenjiro
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 171 Pages: 232-244
- DOI
  10.1016/j.freeradbiomed.2021.05.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-19K10048, KAKENHI-PROJECT-20K11266
[Journal Article] Protective Effects of the Alga Fucoidan Against Amyloid-β-Induced Neurotoxicity in SH-SY5Y Cells2021
- Author(s)
  Nagata Miki、Tsuji Mayumi、Oguchi Tatsunori、Momma Yutaro、Nohara Tetsuhito、Ohashi Hideaki、Ito Naohito、Yamamoto Ken、Udaka Yuko、Sasaki Akiko、Kiuchi Yuji、Numazawa Satoshi
- Journal Title
  
  BPB Reports
  
  Volume: 4 Issue: 6 Pages: 206-213
- DOI
  10.1248/bpbreports.4.6_206
- NAID
  130008136426
- ISSN
  2434-432X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11698
[Journal Article] Toxic Amyloid-β42 Conformer May Accelerate the Onset of Alzheimer's Disease in the Preclinical Stage.2021
- Author(s)
  Futamura A, Hieda S, Mori Y, Kasuga K, Sugimoto A, Kasai H, Kuroda T, Yano S, Tsuji M, Ikeuchi T, Irie K, Ono K.
- Journal Title
  
  J Alzheimers Dis
  
  Volume: 80 Issue: 2 Pages: 639-646
- DOI
  10.3233/jad-201407
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11266, KAKENHI-PROJECT-19H00921, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-20K19111
[Journal Article] Protofibrils of Amyloid-β are Important Targets of a Disease-Modifying Approach for Alzheimer’s Disease2020
- Author(s)
  Ono Kenjiro、Tsuji Mayumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 3 Pages: 952-952
- DOI
  10.3390/ijms21030952
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] Anti-aggregation Effects of Phenolic Compounds on α-synuclein2020
- Author(s)
  Ono Kenjiro、Tsuji Mayumi、Yamasaki Tritia R.、Pasinetti Giulio M.
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 10 Pages: 2444-2444
- DOI
  10.3390/molecules25102444
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Journal Article] High molecular weight amyloid β1‐42 oligomers induce neurotoxicity via plasma membrane damage2019
- Author(s)
  Yasumoto Taro、Takamura Yusaku、Tsuji Mayumi、Watanabe‐Nakayama Takahiro、Imamura Keiko、Inoue Haruhisa、Nakamura Shiro、Inoue Tomio、Kimura Atsushi、Yano Satoshi、Nishijo Hisao、Kiuchi Yuji、Teplow David B.、Ono Kenjiro
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 8 Pages: 9220-9234
- DOI
  10.1096/fj.201900604r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-19K10048, KAKENHI-PROJECT-19K11698, KAKENHI-PROJECT-19K22726, KAKENHI-PROJECT-17H04373, KAKENHI-PROJECT-16K11488, KAKENHI-PROJECT-17K10297
[Journal Article] Pharmacological Potential of Cilostazol for Alzheimer’s Disease2019
- Author(s)
  Ono Kenjiro、Tsuji Mayumi
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 10 Pages: 559-559
- DOI
  10.3389/fphar.2019.00559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Structural dynamics of amyloid-β protofibrils and action of lecanemab as observed by high-speed atomic force microscopy2023
- Author(s)
  Ono K, Nakayama T, Tsuji M, Umeda K, Oguchi T, Konno H, Shinohara M, Kiuch Y, Kodera N, Teplow DB
- Organizer
  CTAD2023(16th Clinical Trials On Alzheimer's Disease)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H03850
[Presentation] Structural dynamics of amyloid-β protofibrils and action of lecanemab as observed by high-speed atomic force microscopy2023
- Author(s)
  Ono K, Nakayama T, Tsuji M, Umeda K, Oguchi T, Konno H, Shinohara M, Kiuch Y, Kodera N, Teplow DB
- Organizer
  CTAD2023(16th Clinical Trials On Alzheimer's Disease)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Vitamin B12 may inhibit the neurotoxicity of Amyloid beta oligomers and protect memory function2023
- Author(s)
  木村篤史、安本太郎、森友紀子、門馬佑太郎、野原哲人、二村明徳、黒田岳志、笠井英世、金野竜太、稗田宗太郎、Teplow David、辻まゆみ、木内祐二、島田　斉、村上秀友、小野賢二郎
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PLANNED-23H03850
[Presentation] 高速原子間力顕微鏡を用いたAβプロトフィブリルの構造動態とレカネマブの作用2023
- Author(s)
  小野賢二郎、中山隆宏、辻まゆみ、梅田健一、小口達敬、紺野宏記、篠原もえ子、木内祐二、古寺哲幸、David B.Teplow
- Organizer
  第42回日本認知症学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Vitamin B12 may inhibit the neurotoxicity of Amyloid beta oligomers and protect memory function2023
- Author(s)
  木村篤史、安本太郎、森友紀子、門馬佑太郎、野原哲人、二村明徳、黒田岳志、笠井英世、金野竜太、稗田宗太郎、Teplow David、辻まゆみ、木内祐二、島田　斉、村上秀友、小野賢二郎
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 高速原子間力顕微鏡を用いたAβプロトフィブリルの構造動態とレカネマブの作用2023
- Author(s)
  小野賢二郎、中山隆宏、辻まゆみ、梅田健一、小口達敬、紺野宏記、篠原もえ子、木内祐二、古寺哲幸、David B.Teplow
- Organizer
  第42回日本認知症学会学術大会
- Data Source
  KAKENHI-PLANNED-23H03850
[Presentation] Aβ高分子oligomer誘発性細胞傷害に対する新規治療薬GT863の保護作用2021
- Author(s)
  門馬佑太郎、辻まゆみ、小口達敬、野原哲人、大橋英朗、井藤尚仁、山本　譲、永田未希、中村史朗、小野賢二郎、木内祐二
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] クルクミンとフェルラ酸によるアミロイドβ誘発性神経細胞傷害への併用効果について2021
- Author(s)
  大橋英朗、辻まゆみ、小口達敬、門馬佑太郎、野原哲人、井藤尚仁、山本謙、永田未希、小野賢二郎、木内祐二
- Organizer
  第６８回昭和大学学士会総会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] 血清BDNFのアルツハイマー病のバイオマーカーの可能性2021
- Author(s)
  森友紀子、辻まゆみ、小口達敬、春日健作、木村篤史、二村明徳、杉本あずさ、笠井英世、黒田岳志、矢野　怜、稗田宗太郎、木内祐二、池内　健、小野賢二郎
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Toxic Aβ42 conformer may accelerate the AD onset in the preclinical stage2021
- Author(s)
  Futamura A, Hieda S, Mori Y, Kasuga K, Sugimoto A, Kasai H, Kuroda T, Yano S, Tsuji M, Ikeuchi T, Irie K, Ono K
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] クルクミンとフェルラ酸のアミロイドβ凝集および神経細胞傷害への相加的効果2021
- Author(s)
  大橋英朗、辻まゆみ、小口達敬、門馬佑太郎、野原哲人、井藤尚仁、山本謙、永田未希、小野賢二郎、木内祐二
- Organizer
  第４０回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] ト神経芽細胞腫SH-SY5Y細胞におけるアミロイドβ誘発性神経毒性に対するfucoidanの保護作用について2021
- Author(s)
  永田未希、辻まゆみ、小口達敬、門馬佑太郎、野原哲人、大橋英朗、井藤尚仁、山本謙、宇髙結子,　佐々木晶子, 木内祐二、沼澤聡
- Organizer
  第377回昭和大学学士会例会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] クルクミン誘導体GT863のアミロイドβ高分子オリゴマー誘発性細胞傷害に対する保護作用2021
- Author(s)
  門馬佑太郎、辻まゆみ、小口達敬、、野原哲人、大橋英朗、井藤尚仁、山本謙、永田未希、中村史朗、小野賢二郎、木内祐二
- Organizer
  第６８回昭和大学学士会総会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] Effects of Vitamin B12 on cognitive function in elderly patients.2021
- Author(s)
  Kimura A, Kinno R, Tsuji M, Ono K.
- Organizer
  Alzheimer’s Association International Conference AAIC2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Video imaging of structural dynamics of amyloid β protofibrils.2021
- Author(s)
  Watanabe-Nakayama T, Tsuji M, Oguchi T, Ono K.
- Organizer
  Alzheimer’s Association International Conference AAIC2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] アミロイドβ高分子oligomer誘発性細胞傷害に対する新規治療薬GT863の保護作用2021
- Author(s)
  門馬佑太郎、辻まゆみ、小口達敬、、野原哲人、大橋英朗、井藤尚仁、山本謙、永田未希、中村史朗、小野賢二郎、木内祐二
- Organizer
  第４０回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] MYRICETIN PREVENTS HIGH MOLECULAR WEIGHT AΒ1-42 OLIGOMER-INDUCED NEUROTOXICITY ONMITOCHONDRIA2021
- Author(s)
  Atsushi Kimura, Yuji Kiuchi, Mayumi Tsuji, Kenjiro Ono
- Organizer
  The 15th International Conference on Alzheimer's & Parkinson's diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] クルクミンとフェルラ酸のアミロイドβ凝集および神経細胞傷害への相加的効果2021
- Author(s)
  大橋英朗、辻まゆみ、小口達敬、門馬佑太郎、野原哲人、井藤尚仁、山本　譲、永田未希、小野賢二郎、木内祐二
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] MYRICETIN PREVENTS HIGH MOLECULAR WEIGHT Aβ1-42 OLIGOMER-INDUCED NEUROTOXICITY ONMITOCHONDRIA2021
- Author(s)
  Atsushi Kimura, Yuji Kiuchi, Mayumi Tsuji, Kenjiro Ono
- Organizer
  The 15th International Conference on Alzheimer's & Parkinson's diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] 藻類であるFucoidanによるアミロイドβ誘発性神経毒性に対する保護作用について2021
- Author(s)
  永田未希、辻まゆみ、小口達敬、門馬佑太郎、野原哲人、大橋英朗、井藤尚仁、山本謙、宇髙結子,　佐々木晶子, 木内祐二、沼澤聡
- Organizer
  第４０回日本認知症学会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] ビタミンB12はアミロイドβオリゴマーによる神経毒性を抗酸化作用により抑制する2020
- Author(s)
  木村篤史、安本太郎、森友紀子、小口達敬、海野真一、海野麻未、中村史朗、井上富雄、辻まゆみ、木内祐二、小野賢二郎
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] High molecular weight amyloid β1-42 oligomers induce neurotoxicity via plasma membrane damage2020
- Author(s)
  Yasumoto Taro、Takamura Yusaku、Tsuji Mayumi、Watanabe-Nakayama Takahiro、Imamura Keiko、Inoue Haruhisa、Nakamura Shiro、Inoue Tomio、Kimura Atsushi、Yano Satoshi、Nishijo Hisao、Kiuchi Yuji、Teplow David B.、Ono Kenjiro
- Organizer
  Alzheimer's Association International Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] 高分子Aβオリゴマーは細胞膜完全性を崩壊し細胞毒性を発揮する2020
- Author(s)
  安本太郎，高村雄策，辻まゆみ，中山隆宏，今村恵子，井上治久，中村史朗，井上富雄，木村篤史，矢野怜，西条寿夫，木内祐二，デービッドテプロフ，小野賢二郎
- Organizer
  第39回　日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] High molecular weight Amyloid β oligomer induces disruption and structural change of cell membrane2020
- Author(s)
  安本太郎、高村雄策、辻まゆみ、中山隆宏、今村恵子、井上治久、中村史朗、井上富雄、木村篤史、矢野怜、西条寿夫、木内祐二、Teplow David B.、小野賢二郎
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Myricetin prevents Aβ oligomer-induced neurotoxicity via cell membrane damage2020
- Author(s)
  Atsushi Kimura, Taro Yasumoto, Yuko Mori, Tatsunori Oguchi, Shiro Nakamura, Tomio Inoue, M Yamada, D.Teplow, Kenjiro Ono, Mayumi Tsuji, Yuji Kiuchi
- Organizer
  The 14th International Conference on Alzheimer's & Parkinson's diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] Myricetin prevents Aβ oligomers-induced neurotoxicity via cell membrane damage2020
- Author(s)
  Kimura Atsushi M.、Yasumoto Taro、Mori Yukiko、Oguchi Tatsunori、Umino Masakazu、Umino Asami、Nakamura Shiro、Inoue Tomio、Yamada Masahito、Teplow David B.、Kiuchi Yuji、Tsuji Mayumi、Ono Kenjiro
- Organizer
  15th International Conference on Alzheimer’s and Parkinson’s Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Vitamin B12 may prevent Aβ oligomer-induced neurotoxicity in Alzheimer's Disease2020
- Author(s)
  Kimura Atsushi M.、Yasumoto Taro、Mori Yukiko、Oguchi Tatsunori、Umino Masakazu、Umino Asami、 Nakamura Shiro、Inoue Tomio、Yamada Masahito、Teplow David B.、Kiuchi Yuji、Tsuji Mayumi、Ono Kenjiro
- Organizer
  Alzheimer’s Association International Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] ミリセチンは抗酸化作用を介し、ミトコンドリア・細胞膜でアミロイドβオリゴマーによる神経毒性を抑制する2020
- Author(s)
  木村篤史、森友起子、小口達敬、海野真一、海野麻未、宇高結子、中村史朗、井上富雄、辻まゆみ、小野賢二郎、木内祐二
- Organizer
  第39回　日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] 高分子 Aβオリゴマーは細胞膜完全性を崩壊し細胞毒性を発揮する2020
- Author(s)
  安本太郎、高村雄策、辻まゆみ、中山隆宏、今村恵子、井上治久、中村史朗、井上富雄、木村篤史、矢野怜、西条寿夫、木内祐二、Teplow David B.、小野賢二郎
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] High molecular weight amyloid β1-42 oligomers induce neurotoxicity via plasma membrane damage2020
- Author(s)
  Taro Yasumoto, Yusaku Takamura, Mayumi Tsuji, Takahiro Nakayama, Keiko Imamura, Haruhisa Inoue, Shiro Nakamura, Tomio Inoue, Atsushi Kimura, Satoshi Yano, Hisao Nishijo, Yuji Kiuchi, David B Teplow, and Kenjiro Ono
- Organizer
  2020 Alzheimer's Association International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] 高分子Aβオリゴマーは細胞膜傷害を介して神経細胞毒性を発揮する2019
- Author(s)
  安本太郎、高村雄策、辻まゆみ、中山隆宏、今村恵子、井上治久、中村史朗、井上富雄、木村篤史、矢野怜、西条寿夫、木内祐二、デービッド・テプロフ、小野賢二郎
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11698
[Presentation] 高分子Aβオリゴマーは細胞膜傷害を介して神経細胞毒性を発揮する2019
- Author(s)
  安本太郎、高村雄策、辻まゆみ、中山隆、今村恵子、井上治久、中村史朗、井上富雄、木村篤史、矢野怜、西条寿夫、木内祐二、デービッド・テプロフ、小野賢二郎
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Supratherapeutic concentrations of cilostazol inhibits β-amyloid oligomerization in vitro.2019
- Author(s)
  Ono K, Shozawa H, Oguchi T, Tsuji M, Yano S, Kiuchi Y
- Organizer
  Alzheimer's Association International Conference 2019(AAIC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] High molecular weight amyloid β1-42 oligomers induce neurotoxicity via plasma membrane damage2019
- Author(s)
  Ono K, Yasumoto T, Takamura Y, Tsuji M, Watanabe-Nakayama T, Imamura K, Inoue H, Nakamura S, Inoue T, Kimura A, Yano S, Nishijo H, Kiuchi Y, Teplow DB
- Organizer
  The Protein Aggregation Conference: From Structure to In Vivo Sequelae,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965
[Presentation] Effects of vitamin B12 on memory fuction in elderly patients2019
- Author(s)
  Atsushi Kimura, Ryuta Kinno, Akinori Futamura, Shohei Nomoto, Satomi Kubota, Yukiko Mori, Azusa Sugimoto, Takeshi Kuroda, Satoshi Yano, Hidetomo Murakami, Mayumi Tsuji, Kenjiro Ono
- Organizer
  60th Annual Meeting of the Japanese Society of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11698

1. Ono Kenjiro (70377381)

# of Collaborated Projects: 3 results

# of Collaborated Products: 43 results
2. 中村史朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 望月秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 池中建介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsuji Mayumi 辻 まゆみ

TSUJI Mayumi 辻 まゆみ

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[Amyloid and heteroamyloid] Formation of meta-aggregates and their toxicity in mixed dementia

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Study on the toxic mechanism of high-molecular A-beta oligomers focusing on membrane damage

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Search for health food ingredients to prevent the onset of Alzheimer's disease targeting inhibition of amyloid B toxicityPrincipal Investigator

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[Journal Article] The Curcumin Derivative GT863 Protects Cell Membranes in Cytotoxicity by Aβ Oligomers2023

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[Journal Article] Extracellular high molecular weight α-synuclein oligomers induce cell death by disrupting the plasma membrane2023

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[Journal Article] Structural Dynamics of Amyloid-β Protofibrils and Actions of Anti-Amyloid-β Antibodies as Observed by High-Speed Atomic Force Microscopy2023

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[Journal Article] Combined Treatment with Curcumin and Ferulic Acid Suppressed the Aβ-Induced Neurotoxicity More than Curcumin and Ferulic Acid Alone2022

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[Journal Article] The effect of α-tocopherol, α- and γ-tocotrienols on amyloid-β aggregation and disaggregation in vitro2021

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[Journal Article] Serum BDNF as a Potential Biomarker of Alzheimer's Disease: Verification Through Assessment of Serum, Cerebrospinal Fluid, and Medial Temporal Lobe Atrophy2021

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[Journal Article] Myricetin prevents high molecular weight Aβ1-42 oligomer-induced neurotoxicity through antioxidant effects in cell membranes and mitochondria2021

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[Journal Article] Protective Effects of the Alga Fucoidan Against Amyloid-β-Induced Neurotoxicity in SH-SY5Y Cells2021

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[Journal Article] Toxic Amyloid-β42 Conformer May Accelerate the Onset of Alzheimer's Disease in the Preclinical Stage.2021

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[Journal Article] Protofibrils of Amyloid-β are Important Targets of a Disease-Modifying Approach for Alzheimer’s Disease2020

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[Journal Article] Anti-aggregation Effects of Phenolic Compounds on α-synuclein2020

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Tsuji Mayumi 辻まゆみ

TSUJI Mayumi 辻まゆみ