Haruma Ken 春間賢

… Alternative Names

HARUMA Ken 春間賢

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Researcher Number	40156526
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Affiliation (Current)	2025: 川崎医科大学, 医学部, 特任研究員
Affiliation (based on the past Project Information) *help	2011 – 2023: 川崎医科大学, 医学部, 教授 2015: 川崎医科大学, 医学部, 特任教授 2003 – 2004: 川崎医科大学, 医学部, 教授 2002: Department of Internal Medicine, Kawasaki Medical School, Professor, 内科学消化器II, 教授 2001: 川崎医科大学, 医学部, 教授 1993 – 2000: 広島大学, 医学部, 講師
Review Section/Research Field	Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Applied health science / 膠原病・アレルギー・感染症内科学 / Gastroenterology / Radiation science
Keywords	Except Principal Investigator mRNA / MCP-1 / VEGF / pS2 / VEGF-C / CD34 / GLUT-1 / histogenesis / MUC-1 mucin / EGF receptor … More / apoptosis / Ki-67 / 浸潤・転移 / 組織発生 / 大腸癌 / Substance P / Interleukin / TGF / Mucus / Dysplasia / Cancer / Colitis / 肥満 / 大腸腫瘍 / サイトカイン / 内視鏡下計測装置 / イメージプロセッサ / 消化管疾患 / 病変部計測システム / 計測装置 / 病変サイズ / 内視鏡 / インターロイキン15 / インターロイキン6 / マイオカイン / 抗インターロイキン6受容体抗体 / インターロイキン6受容体抗体 / サルコぺニア / Nasopharyngeal lymphoid tissue (NALT) / Adenoid / Vaccine / Microparticle / Influenza virus / M cells / 電子顕微鏡 / インフルエンザウイルス / NALT / アデノイド / ワクチン / 微小粒子 / M細胞 / Macrophage / IL-8 / Cytokine / Angiogenesis / Gastric Cancer / レセプター / 転移関連遺伝子 / PD-ECGF / マクロファージ / マイクロファージ / インターロイキン8 / 血管新生 / 胃癌 / ulcerative colitis / invasion metastasis / colorectal carcinoma / MUC-1 / p53 / 発育・進展 / Cathepsin D / MUC1 / pit pattern / Serrated adenoma / h-TERT / TGF-alpha / metastasis / invasion / colorectal cancer / 表面型大腸癌 / MUC-1 ムチン / apoprosis / TGF-α / MUC-1ムチン / 腺癌 / Interleukin-8 / Interleukin 1α / substance P / 実験大腸炎 / GERD / 臨床研究 / 電気抵抗 / 治療抵抗 / プロトンポンプ阻害薬 / 慢性微細炎症 / 胃食道逆流症 / 内臓脂肪 / ＣＴコロノグラフィー / 大腸3次元解析 / アディポサイトカイン / 内臓型肥満 / アデイポカイン / 生活習慣病 / 内臓脂肪型肥満 / CTコロノグラフィー / 大腸CT検査 / SP拮抗剤 / サブスタンスp(SP) / デキストラ硫酸 / 隆起性病変 / Snbstance P受容体拮抗材 / Snbstance P / 硫酸デキストランNa塩 / 大腸炎モデル / ソマトスタチン / ガストリン / K^+-ATPase / H^+ Less

Establishment of measurement system for diagnosis and treatment of gastrointestinal diseases and its clinical application
- Principal Investigator
  
  眞部紀明
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kawasaki Medical School
The effect of myokine, interlukin-6, in colorectal tumor associated with obesity
- Principal Investigator
  
  Matsumoto Hiroshi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kawasaki Medical School
Establishment of evaluation method for endoscopic esophageal mucosa permeability and its clinical application
- Principal Investigator
  
  Manabe Noriaki
- Project Period (FY)
  2014 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kawasaki Medical School
The Relationship between Visceral Fat, Adipoctokines and colorectal neoplasma development evaluated by computed tomography (CT) colonography
- Principal Investigator
  
  MATSUMOTO Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kawasaki Medical School
The development of a vaccine delivery system through M-cells
- Principal Investigator
  
  FUJIMURA Yoshinori
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kawasaki Medical School
REGULATION OF ANGIOGENESIS BY INFLAMATORY CYTOKINES IN HUMAN GASTRIC CARCINOMAS
- Principal Investigator
  
  KITADAI yasuhiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  HIROSIMA UNIVERSITY
炎症性腸疾患の発生機序におけるサブスタンスP mRNAの発現とその抑制機構の研究
- Principal Investigator
  
  KISHIMOTO Shinya (岸本眞也)
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University
Clinicopathologic and genetic analysis on histogenesis and development of colorectal carcinoma
- Principal Investigator
  
  TANAKA Shinji
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University
Clinicopathologic and molecular biologic study on histogenesis and development of colorectal carcinoma
- Principal Investigator
  
  TANAKA Shinji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  HIROSHIMA UNIVERSITY
Experimental studies on oncogenes and proinflammatory factors in experimental colitis
- Principal Investigator
  
  KISHIMOTO Shinya
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  HIROSHIMA UNIVERSITY
胃粘膜内H^+/K^+-ATPaseとヒスチジン脱炭酸酵素の遺伝子発現に関する研究
- Principal Investigator
  
  SUMII Koji
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University

All 2019 2018 2017 2014 2013 Other

All Journal Article Presentation

[Journal Article] Proton pump inhibitor monotherapy is effective to attenuate dyspepsia symptoms associated with gastroesophageal reflux disease: a multicenter prospective observational study.2019
- Author(s)
  Isshi K, Matsuhashi N, Joh T, Higuchi K, Iwakiri K, Kamiya T, Manabe N, Ogawa M, Arihiro S, Haruma K, Nakada K.
- Journal Title
  
  J Gastroenterol.
  
  Volume: NA Issue: 6 Pages: 480-483
- DOI
  10.1007/s00535-019-01546-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461050
[Journal Article] 軽症・重症逆流性食道炎の治療2018
- Author(s)
  眞部紀明，春間　賢
- Journal Title
  
  BIO Clinica
  
  Volume: 33 Pages: 329-333
- Data Source
  KAKENHI-PROJECT-26461050
[Journal Article] Differences in salivary secretory function between patients with erosive esophagitis and those with nonerosive reflux disease.2018
- Author(s)
  Manabe N, Haruma K, Kusunoki H, Kamada T, Hata J.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 4(33) Issue: 4 Pages: 807-813
- DOI
  10.1111/jgh.14002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461050
[Journal Article] Optimal acid suppressive treatment for adequate symptom relief and prevention of the complications of gastroesophageal reflux disease: differences in long-term clinical course and pathophysiology among disease subtypes2017
- Author(s)
  Manabe N, Haruma K.
- Journal Title
  
  Esophagus
  
  Volume: 14 Issue: 2 Pages: 113-121
- DOI
  10.1007/s10388-016-0558-0
- NAID
  40021166161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461050
[Journal Article] SSBEとLSBE，どこがちがう？どうして違う？2017
- Author(s)
  眞部紀明，春間　賢
- Journal Title
  
  消化器内視鏡
  
  Volume: 29 Pages: 1680-1685
- Data Source
  KAKENHI-PROJECT-26461050
[Journal Article] Factors associated with complicated erosive esophagitis: A Japanese multicenter, prospective, cross-sectional study.2017
- Author(s)
  Sakaguchi M, Manabe N, Ueki N, Miwa J, Inaba T, Yoshida N, Sakurai K, Nakagawa M, Yamada H, Saito M, Nakada K, Iwakiri K, Joh T, Haruma K.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 23 Issue: 2 Pages: 318-327
- DOI
  10.3748/wjg.v23.i2.318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461050
[Journal Article] CT Colonographyにおける腸管外病変の描出について2014
- Author(s)
  松田英治、松本啓志、木村佳起、大澤元保、伊東克能、春間賢
- Journal Title
  
  消化器内科
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-23591805
[Journal Article] 大腸3D-CT検査(CT-colonography)における腸管外病変の検出2013
- Author(s)
  松田英治, 松本啓志, 木村佳起, 大澤元保, 守屋和典, 池長弘幸, 原内一, 柳元真一, 吉田悦男, 春間賢, 伊東克能, 村中明
- Journal Title
  
  川崎医療短期大学紀要
  
  Volume: 32 Pages: 21-25
- NAID
  110009551918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591805
[Journal Article] 大腸3D-CT検査(CT colonography)における腸管外病変の検出2013
- Author(s)
  松田英治, 松本啓志, 春間賢, など
- Journal Title
  
  川崎医療短期大学紀要
  
  Volume: 32巻 Pages: 21-25
- NAID
  110009551918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591805
[Journal Article] CT colonographyにおける腸管外病変の描出について
- Author(s)
  松田英治, 松本啓志, 春間賢, など
- Journal Title
  
  消化管内科
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] 大腸CT検査(CT colonography), 内臓脂肪面積測定, アディポカイン測定による大腸腫瘍の評価2014
- Author(s)
  松本啓志, 塩谷昭子, 春間賢
- Organizer
  第100回消化器病学会総会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-04-23
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] 生活習慣病と内視鏡仮想内視鏡(大腸CT検査)を用いた大腸診断と肥満の評価2013
- Author(s)
  木村佳起, 松本啓志, 春間賢
- Organizer
  第85回日本消化器内視鏡学会総会パネルディスカッション
- Place of Presentation
  京都
- Year and Date
  2013-05-10
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] 全大腸内視鏡検査不成功時の仮想内視鏡検査(大腸CT検査)の有効性についての検討2013
- Author(s)
  松本啓志, 春間賢
- Organizer
  第85回日本消化器内視鏡学会総会
- Place of Presentation
  京都
- Year and Date
  2013-05-12
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] 仮想内視鏡（大腸ＣＴ検査）を用いた大腸腫瘍と肥満の評価2013
- Author(s)
  木村佳起、松本啓志、春間賢
- Organizer
  第85回日本消化器内視鏡学会総会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] Relationship among interleukin-6, visceral fat, and colorectal cancer development evaluated by computed tomography (CT) colonography2013
- Author(s)
  Kimura Y, Matsumoto H, Shiotani A, Haruma K
- Organizer
  Digestive Disease Week 2013
- Place of Presentation
  Orlando, USA
- Year and Date
  2013-05-21
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] Relationship among interleukin-6, Visceral Fat, and colorectal cancer development evaluated by computed tomography (CT) colonography2013
- Author(s)
  Yoshiki Kimura, Hiroshi Matsumoto, Motoyasu Oosawa, Ken Haruma
- Organizer
  DDW2013
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] Relationship among interleukin-6, Visceral Fat, and colorectal cancer development evaluated by computed tomography (CT) colonography
- Author(s)
  Kimura Y, Matsumoto H, Haruma K
- Organizer
  Digestive Disease Week 2013
- Place of Presentation
  Orange Country Connvention Center, Orlando, USA
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] 大腸ＣＴ検査 (ＣＴコロノグラフィー) 、内臓脂肪面積測定、アディポカイン測定による大腸腫瘍の評価
- Author(s)
  松本啓志、木村佳起、春間賢
- Organizer
  第100回消化器病学会総会　シンポジウム
- Place of Presentation
  東京　東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] 生活習慣病と内視鏡　仮想内視鏡（大腸CT検査）を用いた大腸診断と肥満の評価
- Author(s)
  木村佳起、松本啓志、春間賢
- Organizer
  第85回日本消化器内視鏡学会総会　パネルディスカッション
- Place of Presentation
  京都京都国際会議場
- Data Source
  KAKENHI-PROJECT-23591805
[Presentation] 全大腸内視鏡検査不成功時の仮想内視鏡検査(大腸CT検査)の有用性についての検討
- Author(s)
  松本啓志、木村佳起、春間賢
- Organizer
  第85回日本消化器内視鏡学会総会
- Place of Presentation
  京都　京都国際会議場
- Data Source
  KAKENHI-PROJECT-23591805

1. YOSHIHARA Masaharu (20211659)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KISHIMOTO Shinya (60093746)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TANAKA Shinji (00260670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SUMII Koji (00116609)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MATSUMOTO Hiroshi (20309553)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
6. SHIOTANI Akiko (80275354)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. Manabe Noriaki (50403572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. 鎌田智有 (50351888)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. HONDA Keisuke (10190266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KITADAI yasuhiko (10304437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. FUJIMURA Yoshinori (30156905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAKEDA Masaharu (10227035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. IKAI Hidenori (20309587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OHUCHI Masanobu (80107185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HARADA Tamotsu (30165021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 林かおり (40263701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 畠二郎 (00368630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 秋定健 (00212423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 中里浩一 (00307993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 岡潔 (80354661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Haruma Ken 春間 賢

HARUMA Ken 春間 賢

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[Journal Article] Proton pump inhibitor monotherapy is effective to attenuate dyspepsia symptoms associated with gastroesophageal reflux disease: a multicenter prospective observational study.2019

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DOI

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[Journal Article] 軽症・重症逆流性食道炎の治療2018

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[Journal Article] Differences in salivary secretory function between patients with erosive esophagitis and those with nonerosive reflux disease.2018

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[Journal Article] Optimal acid suppressive treatment for adequate symptom relief and prevention of the complications of gastroesophageal reflux disease: differences in long-term clinical course and pathophysiology among disease subtypes2017

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Haruma Ken 春間賢

HARUMA Ken 春間賢