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WATANABE Fusao  渡邊 房男

ORCIDConnect your ORCID iD *help
Researcher Number 40183719
Other IDs
Affiliation (based on the past Project Information) *help 2021 – 2023: 大阪医科薬科大学, 医学部, 功労教授
2015 – 2020: 大阪医科大学, 医学部, 准教授
2012 – 2014: 大阪医科大学, 医学部, 講師
2005 – 2008: 大阪医科大学, 医学部, 講師
2000 – 2002: 大阪医科大学, 医学部, 講師 … More
1995 – 1996: 大阪医科大学, 教養部, 講師
1989: 国立循環器病センター研究所, 生化学部, 研究員
1988: 国立循環器病センター, 研究所 生化学部, 研究員
1987: Department of Biochemistry, National Cardiovascular Center Reserach Institute, R, 生化学部, 研究員 Less
Review Section/Research Field
Principal Investigator
Functional biochemistry / General medical chemistry / Metabolomics
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Pathological medical chemistry / Cardiovascular surgery / Thoracic surgery
Keywords
Principal Investigator
fructose 2,6-bisphosphatase / glycolysis / 解糖系 / fructose-6-phosphate 2-kinase / skeletal muscle / フルクトース2,6-二燐酸合成酵素 / ペプチド抗体 / フルクトース-2,6-二リン酸合成分解酵素 / 抗ペプチド抗体 / フルクトース2,6-二燐酸合成分解酵素 … More / 骨格筋 / alternative splicing / fructose 6-phosphate 2-kinase / brain / fructose 2,6 bisphospate / 分子生物学 / フルクトース2.6二燐酸合成酵素 / ホスホフルクトキナーゼ / フルクトース2.6二燐酸 / 択一的スプライシング / フルクトース2,6二燐酸合成酵素 / 脳 / フルクトース2,6二燐酸 / GKRP / HEK293 / HepG2 / 肝細胞 / 細胞内局在性 / glucokinase / グルコースセンサー / 核-細胞質間蛋白質輸送 / 核-細胞質間蛋白資質輸送 / 核‐細胞質間蛋白質輸送 / グルコキナーゼ調節蛋白質 / グルコキナーゼ … More
Except Principal Investigator
虚血再灌流傷害 / 虚血性心筋症 / 心筋細胞 / 心筋保護治療 / 虚血性心不全 / D-amino acid oxidase / レニン結合蛋白質 / cDNA / D-アミノ酸オキシダーゼ / 心筋虚血 / 遺伝子導入 / ペプチド創薬 / eNOS / 薬物送達 / 病変標的治療薬 / 心筋虚血傷害 / 組織標的治療 / 心臓虚血再灌流障害 / 虚血組織送達 / 血管細胞モデル / ドラッグ・リポジショニング / 稀少難病 / マルファン症候群 / 大動脈解離 / 平滑筋細胞 / Marfan症候群 / iPS細胞 / 低酸素培養 / 虚血 / 組織特異的ペプチド / Recombinant mutant proteins / Recombinant protein expression / Leucine zipper structure / Site-directed mutagenesis / Regulation of gene expression / Complementary DNA / Renin-binding protein / 発現の組織特異性 / DNAライブラリー / 部位特異的変異誘導 / 部位特異的突然変異誘導体 / 遺伝子発現機構 / 大量発現と精製 / 遺伝子構造解析 / 変異体蛋白質機能異常 / 変異体蛋白質精製 / 翻訳調節 / 遺伝子発現 / 相補的DNA塩基配列 / 組換体変異蛋白質 / 組換体蛋白質発現 / ロイシンジッパ-構造 / 部位特異的変異誘発 / 遺伝子発現調節 / 相補的DNA / Dーアミノ酸オキシダ-ゼ / complete amino acid sepuence / human urine / Prokallikrein / site-directed mutagenesis / LLC-PK1 cells / グルコース膜輸送 / 人尿プロカリクレイン / LLC-P【K_1】細胞 / D-アミノ酸オキシダーゼ欠損マウス / 変異体 / 試験管内合成 / アミノ酸配列 / ヒト尿プロカリクレイン / LLC-PK_1細胞 / pulmonary hypertension / synthetic vascular prosthesis / gene transduction / bone marrow cells / ハイブリッド / 骨髄間質系細胞 / 肺高血圧症 / 人工血管 / eNOS遺伝子 / 骨髄細胞 / ペプチド / 質量分析 / 培養心筋細胞 / プロテオーム解析 / 培養細胞 / ホーミングペプチド / 重症肺高血圧症 Less
  • Research Projects

    (11 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (13 People)
  •  The development of Cardioprotection therapy with ischemic myocardium-homing peptide along with revascularization

    • Principal Investigator
      Kanki Sachiko
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  The drug screening for individuals of Marfan syndrome using the in vitro vascular cell model made from patient-derived iPS cells

    • Principal Investigator
      Daimon Masahiro
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  The development of new drugs with ischemic myocardium targeting peptides

    • Principal Investigator
      KANKI SACHIKO
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Osaka Medical College
  •  The drug delivery application of the ischemic myocardium targeting peptide

    • Principal Investigator
      Kanki Sachiko
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Osaka Medical College
  •  A novel regulatory mechanism of blood glucose level in hepatocytes independent of hormonal control and its pharmacological applicationPrincipal Investigator

    • Principal Investigator
      WATANABE Fusao
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      Osaka Medical College
  •  重症肺高血圧症に対する一酸化窒素分泌型人工血管の肺動脈位移植術の基礎的検討

    • Principal Investigator
      KATSUMATA Takahiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Osaka Medical College
  •  In Vivo Evaluation of Small Caliber Vascular Prosthesis Impregnated with Bone Marrow Cells Overexpressing eNOS.

    • Principal Investigator
      KATSUMATA Takahiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Osaka Medical College
  •  Regulation Mechanism of Glycolysis in Skeletal MusclePrincipal Investigator

    • Principal Investigator
      WATANABE Fusao
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Osaka Medical College
  •  Regulation of glycolysis by a novel brain-type isozyme of fructose 6-phosphate 2kinase/fructose 2,6-bisphosphatasePrincipal Investigator

    • Principal Investigator
      WATANABE Fusao
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      OSAKA MEDICAL SCHOOL
  •  Biochemical and Molecular Biological Studies on Factors Related to Kidney Transport and Homeostasis under Normal and Pathological States

    • Principal Investigator
      MIYAKE Yoshihiro
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Studies on moiecular and cellular transporting mechanism of nephrons under pathological states

    • Principal Investigator
      MIYAKE Yoshihiro
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Cardiovascular Center Research Institute

All 2013 2006 2005

All Journal Article Presentation

  • [Journal Article] Synthetic vascular prosthesis impregnated with Mesenchymal stem cells overexpressing endothelial nitric oxide synthase.2006

    • Author(s)
      Kanki-Horimoto S, Horimoto H, Mieno S, Kishida K, Watanabe F, Furuya E, Katsumata T.
    • Journal Title

      Circulation 114-1

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] Implantation of Mesenchymal stem cells overexpressing endothelial nitric oxide synthase improved right ventricular impairments caused by pulmonary hypertension.2006

    • Author(s)
      Kanki-Horimoto S, Horimoto H, Mieno S, Kishida K, Watanabe F, Furuya E, Katsumata T.
    • Journal Title

      Circulation 114-1

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Journal Article] Synthetic vascular prosthesis impregnated with genetically modified bone marrow cells produced recombinant proteins.2005

    • Author(s)
      Kanki-Horimoto S, Horimoto H, Mieno S, Kishida K, Watanabe F, Furuya E, Katsumata T.
    • Journal Title

      Artificial Organs 29-10

      Pages: 815-819

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591493
  • [Presentation] HEK293細胞では、肝細胞のグルコキナーゼの局在性を制御するグルコース感知機構が機能していない2013

    • Author(s)
      渡邊房男
    • Organizer
      第86回 日本生化学会大会
    • Place of Presentation
      横浜市西区みなとみらい パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24659448
  • 1.  Kanki Sachiko (40411350)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 3 results
  • 2.  MIENO Shigetoshi (10411373)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  FUKUI Kyoshi (00175564)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KATSUMATA Takahiro (60224474)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  MIYAKE Yoshihiro (40028353)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MOMOI Kyoko (90174359)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  FURUYA Eisuke (00028523)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MIYANO Motoshige (40166187)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  INOUE Hiroyasu (40183743)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Daimon Masahiro (20388268)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  高橋 砂織 (10142184)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  福原 慎二 (70764984)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  友田 紀一郎 (50362843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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