HIRAKAWA Kosei 平川弘聖

… Alternative Names

CHUNG Yong-Suk 鄭容錫

〓容錫テイヨウシヤク

鄭容錫テイヨウシヤク

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Researcher Number	40188652
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016 – 2017: 大阪市立大学, 大学院医学研究科, 医学部附属病院長 2015: 大阪市立大学, 大学院医学研究科, 教授 2011 – 2014: 大阪市立大学, 医学(系)研究科(研究院), 教授 2006 – 2010: 大阪市立大学, 大学院・医学研究科, 教授 2004 – 2007: 大阪市立大学, 医学部, 教授 … More 2001 – 2004: 大阪市立大学, 大学院・医学研究科, 教授 1996: OSAKA CITY UNIVERSITY,MEDICAL SCHOOL,FIRST DEPARTMENT OF SURGERY,LECTURER, 医学部, 講師 1995: 大阪市立大学, 第1外科, 講師 1994: 大阪市立大学, 医学部・第1外科, 講師 1991 – 1993: 大阪市立大学, 医学部, 講師 1989 – 1990: 大阪市立大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Digestive surgery / Digestive surgery Except Principal Investigator Digestive surgery
Keywords	Principal Investigator スキルス胃癌 / Radioimmunodetection / 膵癌 / u-PA / ELAM-1 / Targeting therapy / Nd2 / 腹膜転移 / 癌幹細胞 / 抗癌剤 … More / 分子標的治療 / lymph node metastasis / scirrhous gastric carcinoma / Peritoneal metastasis / ICAM1 / fibroblasts / growth activity / 接着ペプチド / インテグリン / CD44H / 接着分子 / リンパ筋転移 / リンパ節転移 / 遺伝子治療 / 腫瘍免疫 / ICAM-1 / 線維芽細胞 / 増殖活性 / Motility factor / Migrating ability / Glycosylation inhibitor / Invasion and metastasis / Carbohydrate antigen / Pancreatic cancer / 浸潤、転移 / 糖鎖合成阻害剤 / 糖鎖抗原 / 遊走刺激因子 / 遊走能 / 糖鎮合成阻害剤 / 浸潤,転移 / 糖鎮抗原 / Monoclonal antibody / Chimeric Nd2 / Nd2. / Pancreatic caner / ミサイル治療 / Targeting theraapy / キメラNd2 / 血中診断 / イメ-ジング / Nd_2抗体 / 膵癌診断 / SPan-1抗原 / 腫瘍マ-カ- / ミサイル療法 / 腫癌形成性膵炎 / SPanー1抗原 / 癌微小環境 / beclin-1 / LC-3 / p62 / 癌幹細胞マーカー / 胃癌 / クロロキン / オートファジー / 難治癌 / 微小環境 / Met阻害剤 / 抗癌剤耐性 / 腹膜転移能 / 抗癌剤耐性能 / がん幹細胞 / 癌由来線維芽細胞 / スキルス胃癌細胞 / integrin / TGFβ / 胃癌由来線維芽細胞 / シグナル抑制 / HGF / COX-2阻害剤 / 胃癌腹膜転移 / 癌 / スキルス骨癌 / トランスレーショナルリサーチ / FGFR阻害剤 … More Except Principal Investigator Japan Clinical Cancer Research Organization / Japan Research Society for Appropriate Cancer Chem / advanced medicine / clinical trial / adjuvant chemotherapy / gastric caner / chemosensitivity testing / anti-cancer agent / 抗癌剤感受性試験 / UFT / ACTS-GC / NSAS-GC / JCOG / TS-1 / B / 病期IIIA / 根治度B / 胃癌術後補助化学療法 / 日本がん臨床研究推進機構 / 高度先進医療 / 日本がん臨床試験推進機構 / 制癌剤適応研究会 / 先進医療 / 臨床試験 / 補助化学療法 / 胃癌 / 感受性試験 / 抗がん剤 Less

CONQUEST OF THE SCIRRHOUS GASTRIC CANCER: AUTOPHAGY OF CANCER STEM CELLS AND DEVELOPMENT OF MOLECULAR TARGETPrincipal Investigator
- Principal Investigator
  
  Hirakawa Kosei
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka City University
Molecular mechanisms responsible for the development of scirrhous gastric cancer: analysis of cancer stem cells.Principal Investigator
- Principal Investigator
  
  HIRAKAWA Kosei
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka City University
Molecular targeting for scirrhous gastric cancerPrincipal Investigator
- Principal Investigator
  
  HIRAKAWA Kosei
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka City University
In vitro chemosensitivity test to predict chemosensicivity for paclitaxel, using human gastric carcinoma tissues.
- Principal Investigator
  
  TANIGAWA Nobuhiko
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka Medical College
Mechanisms responsible for peritoneal metastasis and lymph node metastasis in scirrhous gastric carcinomaPrincipal Investigator
- Principal Investigator
  
  HIRAKAWA Kosei
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka City University
MOLECULAR BIOLOGIC ANALYSIS AND NEW THERAPEUTIC APPROACH IN INVASION AND METASTASIS OF PANCREATIC CANCER.Principal Investigator
- Principal Investigator
  
  CHUNG Yong-suk
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  OSAKA CITY UNIVERSITY
New strategy in diagnosis and treatment for pancreatic cancer utilizing monoclonal antibodyPrincipal Investigator
- Principal Investigator
  
  CHUNG Yong-Suk
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  OSAKA CITY UNIVERSITY
膵癌の診断・治療へのモノクロ-ナル抗体の応用Principal Investigator
- Principal Investigator
  
  鄭容錫
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka City University

[Book] 基礎と臨床(曽和融生、井藤久雄編)(スキルス胃癌(新編))2010
- Author(s)
  八代正和, 平川弘聖
- Total Pages
  435
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-22390262
[Book] スキルス胃癌ー基礎と臨床ー(曽和融生、井藤久雄編)2010
- Author(s)
  平川弘聖、八代正和
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells2018
- Author(s)
  Miki Yuichiro、Yashiro Masakazu、Okuno Tomohisa、Kitayama Kishu、Masuda Go、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  British Journal of Cancer
  
  Volume: 118 Issue: 6 Pages: 867-877
- DOI
  10.1038/bjc.2017.487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293307
[Journal Article] Pyruvate kinase isozyme M2 and glutaminase might be promising molecular targets for the treatment of gastric cancer2017
- Author(s)
  Kitayama Kishu、Yashiro Masakazu、Morisaki Tamami、Miki Yuichiro、Okuno Tomohisa、Kinoshita Haruhito、Fukuoka Tatsunari、Kasashima Hiroaki、Masuda Go、Hasegawa Tsuyoshi、Sakurai Katsunobu、Kubo Naoshi、Hirakawa Kosei、Ohira Masaichi
- Journal Title
  
  Cancer Sci. 2017 Dec;108(12):2462-2469. doi: 10.1111/cas.13421. Epub 2017 Nov 27.
  
  Volume: 108 Issue: 12 Pages: 2462-2469
- DOI
  10.1111/cas.13421
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K13225, KAKENHI-PROJECT-26293307
[Journal Article] Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells.2017
- Author(s)
  Ishimoto T, Miyake K, Nandi T, Yashiro M, Onishi N, Huang KK, Joyce LN, Kalpana R, Tay ST, Suzuki Y, Cho BC, Kuroda D, Arima K, Izumi D, Iwatsuki M, Baba Y, Oki E, Watanabe M, Saya H, Hirakawa K, Baba H, Tan P.
- Journal Title
  
  Gastroenterology
  
  Volume: in press Issue: 1 Pages: 191-204
- DOI
  10.1053/j.gastro.2017.03.046
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-26293290, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-16K07125, KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-17K10639, KAKENHI-PROJECT-26293307, KAKENHI-PROJECT-17H01401
[Journal Article] CXCL1-Chemokine (C-X-C Motif) Receptor 2 Signaling Stimulates the Recruitment of Bone Marrow-Derived Mesenchymal Cells into Diffuse-Type Gastric Cancer Stroma.2016
- Author(s)
  Kasashima H, Yashiro M, Nakamae H, Kitayama K, Masuda G, Kinoshita H, Fukuoka T, Hasegawa T, Nakane T, Hino M, Hirakawa K, Ohira M.
- Journal Title
  
  Am J Pathol
  
  Volume: 186 Pages: 3028-3039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293307
[Journal Article] Clinicopathological Correlations of Autophagy-related Proteins LC3, Beclin 1 and p62 in Gastric Cancer2016
- Author(s)
  Masuda Go, Yashiro M, Kitayama K, Miki Y, Kasashima H, Kinoshita H, Morisaki T, Fukuoka T, Hasegawa T, Sakurai K, Toyokawa T, Kubo N, Tanaka H, Muguruma K, Masaichi O, Hirakawa K
- Journal Title
  
  Anticancer Research
  
  Volume: 36 Pages: 129-136
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293307
[Journal Article] Cancer-associated fibroblasts might sustain the stemness of scirrhous gastric cancer cells via transforming growth factor-β signaling2014
- Author(s)
  Hasegawa T Yashiro M, Nishii T, Matsuoka J, Morisaki T, Fukuoka T, Shimizu K, Shimizu T, Miwa A, Hirakawa K
- Journal Title
  
  Int J Cancer
  
  Volume: 134 Pages: 1785-1795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer.2014
- Author(s)
  Kasashima H, Yashiro M, Kinoshita H, Fukuoka T, Morisaki T, Masuda G, Sakurai K, Kubo N, Ohira M, Hirakawa K
- Journal Title
  
  Cancer Lett.
  
  Volume: 354 Issue: 2 Pages: 438-446
- DOI
  10.1016/j.canlet.2014.08.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390329, KAKENHI-PROJECT-26293307
[Journal Article] Cancer-associated fibroblasts might sustain the stemness of scirrhous gastric cancer cells via transforming growth factor-beta signaling.2014
- Author(s)
  Hasegawa T, Yashiro M, Nishii T, Matsuoka J, Fuyuhiro Y, Morisaki T, Fukuoka T, Shimizu K, Shimizu T, Miwa A, Hirakawa K.
- Journal Title
  
  Int J Cancer
  
  Volume: 134 Issue: 8 Pages: 1785-95
- DOI
  10.1002/ijc.28520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262, KAKENHI-PROJECT-23390329, KAKENHI-PROJECT-26293307
[Journal Article] Association of MHC class I expression and lymph node metastasis of gastric carcinoma2013
- Author(s)
  Yoshii M, Tanaka H, Ohira M, Muguruma K, Sakurai K, Kubo N, Yashiro M, Sawada T, Hirakawa K
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 60 Pages: 611-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Hypoxia stimulates the EMT of gastric cancer cells through autocrine TGFbeta signaling2013
- Author(s)
  Matsuoka J, Yashiro M, Doi Y, Fuyuhiro Y, Kato Y, Shinto O, Aomatsu N, Hirakawa T, Hasegawa T, Shimizu K, Shimizu T, Miwa A, Yamada N, Sawada T, Hirakawa K
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] IGF-1 receptor and IGF binding protein-3 might predict prognosis of patients with resectable pancreatic cancer2013
- Author(s)
  Hirakawa T, Yashiro M, Murata A, Hirata K, Kimura K, Amano R, Yamada N, Nakata B, Hirakawa K
- Journal Title
  
  BMC Cancer
  
  Volume: 13 Pages: 392-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] MUC1 and HER2 might be associated with invasive phenotype of intraductal papillary mucinous neoplasm (IPMN)2013
- Author(s)
  Ohira G, Kimura K, Ymada N, Amano R, Nakata B, Doi Y, Murata A, Yashiro M, Tanaka S, Ohsawa M, Wakasa K, Hirakawa K
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Glyoxalase 1 as a candidate for indicating the metastatic potential of SN12C human renal cell carcinoma cell clones2013
- Author(s)
  Tanaka T, Kuramitsu Y, Wang Y, Baron B, Kitagawa T, Tokuda K, Hirakawa K, Yashiro M, Naito S, Nakamura K
- Journal Title
  
  Oncol Rep
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] A prognostic indicator for the resection of liver metastasis of colorectal cancer2013
- Author(s)
  Amano R, Yamada N, Nakata B, Kimura K, Yashiro M, Ohira M, Hirakawa K
- Journal Title
  
  Surg Today
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Successful resection of esophageal cancer with right aortic arch by video-assisted thoracoscopic surgery : a case report2013
- Author(s)
  Kubo N, Ohira M, Lee T, Sakurai K, Toyokawa T, Tanaka H, Muguruma K, Kimura K, Nagahara H, Noda E, Amano R, Ohtani H, Yamashita Y, Yashiro M, Maeda K, Hirakawa K
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 1635-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Predictive value of expression of ERCC 1 and GST-p for 5-fluorouracil/oxaliplatin chemotherapy in advanced colorectal cancer2013
- Author(s)
  Noda E, Maeda K, Inoue T, Fukunaga S, Nagahara H, Shibutani M, Amano R, Nakata B, Tanaka H, Muguruma K, Yamada N, Yashiro M, Ohira M, Ishikawa T, Hirakawa K
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 59 Pages: 130-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] c-Kit expression as a prognostic molecular marker in patients with basal-like breast cancer2013
- Author(s)
  Kashiwagi S, Yashiro M, Takashima T, Aomatsu N, Kawajiri H, Ogawa Y, Onoda N, Ishikawa T, Wakasa K, Hirakawa K
- Journal Title
  
  Br J Surg
  
  Volume: 100 Pages: 490-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] SPan-1 is a useful prognostic marker for patients with stage IV gastric cancer who underwent palliative gastrectomy : a retrospective multivariate study2013
- Author(s)
  Kubo N, Ohira M, Sakurai K, Toyokawa T, Tanaka H, Muguruma K, Nagahara H, Kimura K, Noda E, Amano R, Yamada N, Yashiro M, Maeda K, Sawada T, Hirakawa K
- Journal Title
  
  World J Surg
  
  Volume: 37 Pages: 1681-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Prognostic predictive values of gemcitabine sensitivity-related gene products for unresectable or recurrent biliary tract cancer treated with gemcitabine alone2013
- Author(s)
  Murata A, Amano R, Yamada N, Kimura K, Yashiro M, Nakata B, Hirakawa K
- Journal Title
  
  World J Surg Oncol
  
  Volume: 11 Pages: 117-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Expression of E-cadherin and KRAS mutation may serve as biomarkers of cetuximab-based therapy in metastatic colorectal cancer2013
- Author(s)
  Nakamoto K, Nagahara H, Maeda K, Noda E, Inoue T, Yashiro M, Nishiguchi Y, Ohira M, Hirakawa K
- Journal Title
  
  Oncol Lett
  
  Volume: 5 Pages: 1295-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] A cMet inhibitor increases the chemosensitivity of cancer stem cells to the irinotecan in gastric carcinoma2013
- Author(s)
  Yashiro M, Nishii T, Matsuzaki T, Hasegawa T, Morisaki T, Fukuoka T, Hirakawa K
- Journal Title
  
  Br J Cancer
  
  Volume: 109 Pages: 2619-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] A c-Met inhibitor increases the chemosensitivity of cancer stem cells to the irinotecan in gastric carcinoma.2013
- Author(s)
  Yashiro M, Nishii T, Hasegawa T, Matsuzaki T, Morisaki T, Fukuoka T, Hirakawa K.
- Journal Title
  
  Br J Cancer
  
  Volume: 109 Issue: 10 Pages: 2619-28
- DOI
  10.1038/bjc.2013.638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262, KAKENHI-PROJECT-23390329
[Journal Article] Expression of Forkhead box P3 in tumour cells causes immunoregulatory function of signet ring cell carcinoma of the stomach2012
- Author(s)
  Yoshii M, Tanaka H, Ohira M, Muguruma K, Yashiro M, Sawada T, Hirakawa K
- Journal Title
  
  Br J Cancer
  
  Volume: 106 Pages: 1668-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks2012
- Author(s)
  Kataoka Y, Mukohara T, Tomioka H, Funakoshi Y, Kiyota N, Fujiwara Y, Yashiro M, Hirakawa K, Hirai M, Minami H
- Journal Title
  
  Invest New Drugs
  
  Volume: 30 Pages: 1352-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] VEGF-A/VEGFR-2 Signaling Plays an Important Role for the Motility of Pancreas Cancer Cells2012
- Author(s)
  DoiY,YashiroM,YamadaN,AmanoR,NodaS,HirakawaK
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19 Pages: 2733-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Correlation between efficacy of PSK postoperative adjuvant immunochemotherapy for gastric cancer and expression of MHC class I2012
- Author(s)
  Ito G, Tanaka H, Ohira M, Yoshii M, Yashiro M, Yamada N, Maeda K, Sawada T, Hirakawa K
- Journal Title
  
  Exp Ther Med
  
  Volume: 3 Pages: 925-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] CD133 is a useful surrogate marker for predicting chemosensitivity to neoadjuvant chemotherapy in breast cancer2012
- Author(s)
  Aomatsu N, Yashiro M, Kashiwagi S, Takashima T, Ishikawa T, Ohsawa M, Wakasa K, Hirakawa K
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Role of the stemness factors sox2, oct3/4, and nanog in gastric carcinoma2012
- Author(s)
  Matsuoka J, Yashiro M,, Sakurai K, Kubo N, Tanaka H, Muguruma K, Sawada T, Ohira M, Hirakawa K.
- Journal Title
  
  J Surg Res.
  
  Volume: 174 Issue: 1 Pages: 130-135
- DOI
  10.1016/j.jss.2010.11.903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262, KAKENHI-PROJECT-23390329
[Journal Article] Concurrent biological targeting therapy of squamous cell carcinoma of the esophagus with cetuximab and trastuzumab2012
- Author(s)
  Yamazaki M, Yamashita Y, Kubo N, Yashiro M, Ohira M, Ako E, Tanaka H, Muguruma K, Sawada T, Hirakawa K
- Journal Title
  
  Oncol Rep
  
  Volume: 28 Pages: 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Correlation between efficacy of PSK postoperative adjuvant immunochemotherapy for gastric cancer and expression of MHC class2012
- Author(s)
  Ito G, Tanaka H, Ohira M, Yoshii M, Muguruma K, Kubo N, Yashiro M,, Yamada N, Maeda K, Sawada T, Hirakawa K
- Journal Title
  
  Exp Ther Med
  
  Volume: 3 Issue: 6 Pages: 925-30
- DOI
  10.3892/etm.2012.537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumorigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-beta2012
- Author(s)
  Katsuno Y, Ehata S, Yashiro M, Yanagihara K, Hirakawa K, Miyazono K
- Journal Title
  
  J Pathol
  
  Volume: 228(3) Pages: 391-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Successful resection of esophageal carcinoma associated with double aortic arch : a case report2012
- Author(s)
  Kubo N, Ohira M, Yamashita Y, Sakurai K, Kimura K, Nagahara H, Noda E, Amano R, Yashiro M, Maeda K, Hirakawa K
- Journal Title
  
  Anticancer Res
  
  Volume: 32 Pages: 3351-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Multipeptide immune response to cancer vaccine IMA901 after single dose cyclophosphamide associates with longer patient survival2012
- Author(s)
  Hirakawa K (他38名)
- Journal Title
  
  Nat Med
  
  Volume: 18 Pages: 1254-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] PI3K/Akt signalling is required for the attachment and spreading, and growth in vivo of metastatic scirrhous gastric carcinoma2012
- Author(s)
  Matsuoka T, Yashiro M, Nishioka N, Hirakawa K, Olden K, Roberts JD
- Journal Title
  
  Br J Cancer
  
  Volume: 106 Pages: 1535-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] NC-6301, a polymeric micelle rationally optimized for effective release of docetaxel, is potent but is less toxic than native docetaxel in vivo2012
- Author(s)
  Harada M, Iwata C, Saito H, Yashiro M, Hirakawa K, Miyazono K, Kato Y, Kano MR
- Journal Title
  
  Int J Nanomedicine
  
  Volume: 7 Pages: 2713-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Plasminogen activator inhibitor 1 RNAi suppresses gastric cancer metastasis in vivo2012
- Author(s)
  Nishioka N, Matsuoka T, Yashiro M, Hirakawa K, Roberts JD
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Pages: 228-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis2012
- Author(s)
  Rafi M, Cabral H, Kano MR, Mi P, Iwata C, Yashiro M, Hirakawa K, Miyazono K, Nishiyama N, Kataoka K
- Journal Title
  
  J Control Release
  
  Volume: 159 Pages: 189-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Cancer-associated orthotopic myofibroblasts stimulates the motility of gastric carcinoma cells2012
- Author(s)
  Fuyuhiro Y, Yashiro M, Noda S, Matsuoka J, Hasegawa T, Kato Y, Sawada T, Hirakawa K
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Pages: 797-805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Role of the stemness factors sox2, oct3/4, and nanog in gastric carcinoma2012
- Author(s)
  Matsuoka J, Yashiro M, Sakurai K, Kubo N, Ohira M, Hirakawa K
- Journal Title
  
  J Surg Res
  
  Volume: 174 Pages: 130-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Transforming growth factor-beta decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells2011
- Author(s)
  Ehata S, Johansson E, Katayama R, Koike S, Watanabe A, Hoshino Y, Katsuno Y, Komuro A, Koinuma D, Kano MR, Yashiro M, Hirakawa K, Aburatani H, Fujita N, Miyazono K
- Journal Title
  
  Oncogene.
  
  Volume: 30 Pages: 1693-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Identification of HLA-A*2402-restricted epitope peptide derived from ERas oncogene expressed in human scirrhous gastric cancer2011
- Author(s)
  Iwauchi T, Tanaka H, Yamazoe S, Yashiro M, Kubo N, Muguruma K, Sawada T, Ohira M, Hirakawa K
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 683-9
- NAID
  10029291798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells2011
- Author(s)
  Yashiro M, Qiu H, Hasegawa T, Zhang X, Matsuzaki T, Hirakawa K
- Journal Title
  
  Br J Cancer
  
  Volume: 105 Pages: 1522-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Effects of acute and chronic hypoxia on the radiosensitivity of gastric and esophageal cancer cells2011
- Author(s)
  Kato Y, Yashiro M, Fuyuhiro Y, Kashiwagi S, Matsuoka J, Hirakawa T, Noda S, Aomatsu N, Ohira M, Hirakawa K
- Journal Title
  
  Anticancer Res
  
  Volume: 31 Pages: 3369-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Upregulation of cancer-associated myofibroblasts by TGF-beta from scirrhous gastric carcinoma cells2011
- Author(s)
  Fuyuhiro Y, Yashiro M, Noda S, Kashiwagi S, Matsuoka J, Doi Y, Kato Y, Hasegawa T, Sawada T, Hirakawa K
- Journal Title
  
  Br J Cancer
  
  Volume: 105 Pages: 996-1001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Bone morphogenetic protein-2 and -4 play tumor suppressive roles in human diffuse-type gastric carcinoma2011
- Author(s)
  Shirai YT, Ehata S, Yashiro M, Yanagihara K, Hirakawa K, Miyazono K
- Journal Title
  
  Am J Pathol
  
  Volume: 179 Pages: 2920-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] A FGFR2 inhibitor, Ki23057, enhances the chemosensitivity of drug-resistant gastric cancer cells2011
- Author(s)
  Qiu H, Yashiro M, Zhang X, Miwa A, Hirakawa K
- Journal Title
  
  Cancer Lett
  
  Volume: 307 Pages: 47-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Linoleic acid enhances angiogenesis through suppression of angiostatin induced by plasminogen activator inhibitor 12011
- Author(s)
  Nishioka N, Matsuoka T, Yashiro M, Hirakawa K, Olden K, Roberts JD
- Journal Title
  
  Br J Cancer
  
  Volume: 105 Pages: 1750-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Advantages of adjuvant chemotherapy for patients with triple-negative breast cancer at Stage II : usefulness of prognostic markers E-cadherin and Ki672011
- Author(s)
  Kashiwagi S, Yashiro M, Takashima T, Aomatsu N, Ishikawa T, Hirakawa K
- Journal Title
  
  Breast Cancer Res
  
  Volume: 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] RhoA/ROCK signaling mediates plasticity of scirrhous gastric carcinoma motility2011
- Author(s)
  Matsuoka T, Yashiro M, Shinto O, Hirakawa K
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 28 Pages: 627-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Borrmann's macroscopic criteria and p-Smad2 expression are useful predictive prognostic markers for cytology-positive gastric cancer patients without overt peritoneal metastasis2011
- Author(s)
  Noda S, Yashiro M, Toyokawa T, Sawada T, Hirakawa K
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 18 Pages: 3718-25
- NAID
  130004436449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Synergistic antitumor effects of FGFR2 inhibitor with 5-fluorouracil on scirrhous gastric carcinoma.2010
- Author(s)
  Yashiro M, Hirakawa, K.
- Journal Title
  
  Int J Cancer
  
  Volume: 126 Pages: 1004-1016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Cancer-stromal interactions in scirrhous gastric carcinoma.2010
- Author(s)
  Yashiro M, Hirakawa, K.
- Journal Title
  
  Cancer Microenvironment
  
  Volume: 3 Pages: 127-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells.2010
- Author(s)
  Yashiro M, Hirakawa, K.
- Journal Title
  
  Br J Cancer.
  
  Volume: 102 Pages: 844-851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Establishment and characterization of a new hypoxia-resistant cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric carcinoma.2010
- Author(s)
  Yashiro M, Hirakawa, K.
- Journal Title
  
  Br J Cancer.
  
  Volume: 102 Pages: 898-907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390262
[Journal Article] Direct cancer-stromal interaction increases fibroblast proliferation and enhances invasive properties of scirrhous-type gastric carcinoma cells.2009
- Author(s)
  Semba, S., Kodama, Y., Ohnuma, K., Mizuuchi, E., Masuda, R., Yashiro, M.., Hirakawa, K., Yokozaki, H.
- Journal Title
  
  Br J Cancer
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer.2009
- Author(s)
  Matsuzaki, T., Yashiro, M.., Kaizaki, R., Yasuda, K., Doi, Y., Sawada, T., Ohira, M., Hirakawa, K.
- Journal Title
  
  Cancer Sci
- NAID
  10027198595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Allelic imbalance at p53 and microsatellite instability are predictive markers for resistance to chemotherapy in gastric carcinoma.2009
- Author(s)
  Yashiro, M.., Inoue, T., Nishioka, N., Matsuoka, T., Bol, C.R., Hirakawa, K.
- Journal Title
  
  Ann Surg Oncol 16
  
  Pages: 2926-2935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Diffuse-type gastric carcinoma : progression, angiogenesis, and transforming growth factor beta signaling2009
- Author(s)
  Komuro A, Yashiro M, Iwata C, Morishita Y, Johansson E, Matsumoto Y, Watanabe Aburatani H, Miyoshi H, Kiyono K, Shirai YT, Suzuki HI, Hirakawa K, Kano MR, Miyazono K.
- Journal Title
  
  J Natl Cancer Inst 15 ; 101
  
  Pages: 592-604
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Co-expression of keratinocyte growth factor and K-sam is an independent prognostic factor in gastric carcinoma.2009
- Author(s)
  Toyokawa, T., Yashiro, M., Hirakawa, K.
- Journal Title
  
  Oncol Rep 21
  
  Pages: 875-880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Synergistic antitumor effects of FGFR2 inhibitor with 5-fluorouracil on scirrhous gastric carcinoma.2009
- Author(s)
  Yashiro, M.., Shinto, O., Nakamura, K., Tendo, M., Matsuoka, T., Matsuzaki, T., Kaizaki, R., Miwa, A., Hirakawa, K.
- Journal Title
  
  Int J Cancer
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Epigenetic regulation of the embryonic oncogene ERas in gastric cancer cells2009
- Author(s)
  Yashiro M, Yasuda K, Hirakawa K
- Journal Title
  
  International journal of oncology 35
  
  Pages: 997-1003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Epigenetic regulation of the embryonic oncogene ERas in gastric cancer cells.2009
- Author(s)
  Yashiro, M., Yasuda, K., Nishii, T., Kaizaki, R., Sawada, T., Ohira, M., Hirakawa, K.
- Journal Title
  
  Int J Oncol 35
  
  Pages: 997-1003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Allelic Imbalance at p53 and Microsatellite Instability Are Predictive Markers for Resistance to Chemotherapy in Gastric Carcinoma2009
- Author(s)
  Yashiro M, Inoue T, Hirakawa K
- Journal Title
  
  Annals of surgical oncology 16
  
  Pages: 2926-2935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Effects of VEGFR-3 phosphorylation inhibitor on lymph node met astasis in an orthotopic diffuse-type gastric carcinoma model.2009
- Author(s)
  Yashiro M, Shinto O, Hirakawa K.
- Journal Title
  
  British journal of cancer 101
  
  Pages: 1100-1106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Effects of VEGFR-3 phosphorylation inhibitor on lymph node metastasis in an orthotopic diffuse-type gastric carcinoma model.2009
- Author(s)
  Yashiro, M., Shinto, O., Nakamura, K., Tendo, M., Matsuoka, T., Matsuzaki, T., Kaizaki, R., Ohira, M., Miwa, A., Hirakawa, K
- Journal Title
  
  Br J Cancer 101
  
  Pages: 1100-1106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Expression of ERas oncogene in gastric carcinoma.2009
- Author(s)
  Kaizaki, R., Yashiro, M.., Shinto, O., Yasuda, K., Hirakawa, K.
- Journal Title
  
  Anticancer Res 29
  
  Pages: 2189-2193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling.2009
- Author(s)
  Komuro, A., Yashiro, M.., Iwata, C., Morishita, Y., Johansson, E., Matsumoto, Y., Watanabe, A., Aburatani, H., Miyoshi, H., Kiyono, K., Shirai, Y.T., Suzuki, H.I., Hirakawa, K.., Kano, M.R., Miyazono, K
- Journal Title
  
  J Natl Cancer Inst 101
  
  Pages: 592-604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] A novel transforming growth factor beta receptor kinase inhibitor, A-77, prevents the peritoneal dissemination of scirrhous gastric carcinoma.2008
- Author(s)
  Kawajiri, H., Yashiro, M., Shinto, O., Nakamura, K., Tendo, M., Takemura, S, Node, M., Hamashima, Y., Kajimoto, T., Sawada, T., Ohira, M., Hirakawa, K.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 2850-2860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] A Novel Transforming Growth Factor beta Receptor Kinase Inhibitor, A-77, Prevents the Peritoneal Dissemination of Scirrhous Gastric Carcinoma.2008
- Author(s)
  Kawajiri H, Yashiro M, Hirakawa K.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 2850-2860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Ulcerative colitis-associated colorectal cancer is frequently associated with the microsatellite instability pathway.2008
- Author(s)
  Fujiwara, I., Yashiro, M.., Kubo, N., Maeda, K., Hirakawa, K.
- Journal Title
  
  Dis Colon Rectum 51
  
  Pages: 1387-1394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] A novel transforming growth factor beta receptor kinase inhibitor, A-77, prevents the peritoneal dissemination of scirrhous gastric carcinoma.2008
- Author(s)
  Kawajiri H, Yashiro M, Shinto O, Nakamura K, Tendo M, Takemura S, Node M, Hamashima Y, Kajimoto T, Sawada T, Ohira M, Hirakawa K.
- Journal Title
  
  Clinical Cancer Research 14
  
  Pages: 2850-60
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] A novel angiogenesis inhibitor,Ki23057,is useful for preventing the progression of colon cancer and the spreading of cancer cells to the liver.2007
- Author(s)
  Sakurai K, Yashiro M, Hirakawa K.
- Journal Title
  
  European Journal of Cancer 43
  
  Pages: 2612-2620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] FGF-R2/K-samllを分子標的としたスキルス胃癌の新規治療法2007
- Author(s)
  八代正和, 平川弘聖
- Journal Title
  
  消化器科 44
  
  Pages: 447-454
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Selective cyclooxygenase-2 inhibitor downregulates the paracrine epithehial-mesenchymal interactions of growth in scirrhous gastric carcinoma.2007
- Author(s)
  Yashiro M, Hirakawa, K.
- Journal Title
  
  International Journal of Cancer 120
  
  Pages: 686-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Selective cyclooxygenase-2 inhibitor downregulates the paracrine epithelial-mesenchymal interactions of growth in scirrhous gastric carcinoma.2007
- Author(s)
  Yashiro, M.., Nakazawa, K., Tendo, M., Kosaka, K., Shinto, O., Hirakawa, K.
- Journal Title
  
  Int J Cance 120
  
  Pages: 686-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis.2007
- Author(s)
  Iwata, C., Kano, M.R., Komuro, A., Oka, M., Kiyono, K., Johansson, E., Morishita, Y., Yashiro, M.., Hirakawa, K.., Kaminishi, M., Miyazono, K.
- Journal Title
  
  Cancer Res 67
  
  Pages: 10181-10189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Prognostic impact of PCR-based identification of isolated tumour cells in the peritoneal lavage fluid of gastric cancer patients who underwent a curative R0 resection.2007
- Author(s)
  Katsuragi, K., Yashiro, M.., Sawada, T., Osaka, H., Ohira, M., Hirakawa, K.
- Journal Title
  
  Br J Cancer 97
  
  Pages: 550-556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.2007
- Author(s)
  Kano, M.R., Bae, Y., Iwata, C., Morishita, Y., Yashiro, M.., Oka, M., Fujii, T., Komuro, A., Kiyono, K., Kaminishi, M., Hirakawa, K.., Ouchi, Y., Nishiyama, N., Kataoka, K., Miyazono, K.
- Journal Title
  
  Proc Natl Acad Sci U S A 104
  
  Pages: 3460-3465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling2007
- Author(s)
  Kano MR, Bae Y, Iwata C, Morishita Y, Yashiro M, Oka M, Fujii T, Komuro A, Kiyono K, Kaminishi M, Hirakawa K, Ouchi Y, Nishiyama N, Kataoka K and Miyazono K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 104
  
  Pages: 3460-3465
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Selective cyclooxygenase-2 inhibitor downregulates the paracrine epithelial-mesenchymal interactions of growth in scirrhous gastric carcinoma2007
- Author(s)
  Yashiro M, Nakazawa K, Tendo M, Kosaka K, Shinto O, Hirakawa K
- Journal Title
  
  Int J Cancer 120
  
  Pages: 686-693
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] A novel molecular targeting compound as K-samII/FGF-R2 phosphorylation inhibitor, Ki23057, for Scirrhous gastric cancer.2006
- Author(s)
  Nakamura, K., Yashiro, M., Matsuoka, T., Tendo, M., Shimizu, T., Miwa, A., Hirakawa, K
- Journal Title
  
  Gastroenterology 131
  
  Pages: 1530-1541
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] A novel molecular targeting compound as K-samII/FGF-R2 phosphorylation inhibitor, Ki23057, for Scirrhous gastric cancer2006
- Author(s)
  Nakamura K, Yashiro M, Matsuoka T, Tendo M, Shimizu T, Miwa A, Hirakawa K.
- Journal Title
  
  Gastroenterology 131
  
  Pages: 1530-1541
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] A synergic inhibitory-effect of combination with selective cyclooxygenase-2 inhibitor and S-1 on the peritoneal metastasis for scirrhous gastric cancer cells.2006
- Author(s)
  Tendo, M., Yashiro, M.., Nakazawa, K., Yamada, N., Sawada, T., Ohira, M., Hirakawa, K.
- Journal Title
  
  Cancer Lett 244
  
  Pages: 247-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] A novel molecular targeting compound as K-samII/FGF-R2 phosphorylation inhibitor, Ki23057, for Scirrhous gastric cancer.2006
- Author(s)
  Nakamura, K., Yashiro, M.., Matsuoka, T., Tendo, M., Shimizu, T., Miwa, A., Hirakawa, K.
- Journal Title
  
  Gastroenterology 131
  
  Pages: 1530-1541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Antitumor effect of trastuzumab for pancreatic cancer with high HER-2 expression and enhancement of effect by combined therapy with gemcitabine.2006
- Author(s)
  Kimura, K., Sawada, T., Komatsu, M., Inoue, M., Muguruma, K., Nishihara, T., Yamashita, Y., Yamada, N., Ohira, M., Hirakawa, K.
- Journal Title
  
  Clin Cancer Res 12
  
  Pages: 4925-4932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] スキルス胃癌における縁組化は癌の進展にどのようにかかわるのか?2006
- Author(s)
  八代正和, 井上透, 深田鉄二, 大平雅一, 平川弘聖
- Journal Title
  
  分子消化器病 3巻3号
  
  Pages: 245-250
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Decreased expression of the adhesion molecule desmoglein-2 is associated with diffuse-type gastric carcinoma.2006
- Author(s)
  Yashiro, M.., Nishioka, N., Hirakawa, K.
- Journal Title
  
  Eur J Cancer 42
  
  Pages: 2397-2403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] Simultaneous bilateral laparoscopic adrenalectomy for adrenocorticotropic hormone-independent macronodular adrenal hyerplasia: report of a case.2006
- Author(s)
  Kubo, N., Onoda, N., Ishikawa, T., Ogawa, Y., Takashima, T., Yamashita, Y., Tahara, H., Inaba, M., Hirakawa, K.
- Journal Title
  
  Surg Today 36
  
  Pages: 642-646
- NAID
  10017614290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390369
[Journal Article] TS-1による術後補助療法中に発症しWeekly Docetaxel療法により著効をみた胃癌腹膜播種の1例2005
- Author(s)
  高島勉, 仲田文造, 平川弘聖
- Journal Title
  
  癌と化学療法 32・7
  
  Pages: 1041-1044
- Data Source
  KAKENHI-PROJECT-16209041
[Journal Article] CD54 Expression Is Predictive for Lymphatic Spread in Human Gastric Carcinoma.2005
- Author(s)
  Yashiro M, Sunami T, Hirakawa K
- Journal Title
  
  Dig Dis Sci. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470260
[Journal Article] K-ras mutation influences macroscopic features of gastric carcinoma.2005
- Author(s)
  Yashiro M, Nishioka N, Hirakawa K
- Journal Title
  
  J Surg Res 124
  
  Pages: 74-78
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470260
[Journal Article] ICAM-2 gene therapy for peritoneal dissemination of scirrhous gastric carcinoma.2004
- Author(s)
  Tanaka H, Yashiro M, Sunami T, Sakate Y, Kosaka K, Hirakawa K
- Journal Title
  
  Clin Cancer Res 10
  
  Pages: 4885-4892
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470260
[Journal Article] Novel models for human scirrhous gastric carcinoma in vivo.2004
- Author(s)
  Takemura S, Yashiro M, Sunami T, Tendo M, Hirakawa K
- Journal Title
  
  Cancer Sci 95
  
  Pages: 893-900
- NAID
  10014197818
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470260
[Journal Article] ICAM-2 Gene Therapy for Peritoneal Dissemination of Scirrhous Gastric Carcinoma2004
- Author(s)
  Tanaka H, Yashiro M, Hirakawa K, et al.
- Journal Title
  
  Clinical Cancer Research 10
  
  Pages: 4885-4892
- Data Source
  KAKENHI-PROJECT-13470260
[Journal Article] Is a lymph node detected by the dye-guided method a true sentinel node in gastric cancer?2004
- Author(s)
  Osaka H, Yashiro M, Sawada T, Katsuragi K, Hirakawa K
- Journal Title
  
  Clin Cancer Res 10
  
  Pages: 6912-6918
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470260
[Journal Article] Usefulness of inhibiting The Lymph Node Metastasis in Human Gastric Carcinoma by B7-1 Gene Transfection2004
- Author(s)
  Sakate Y, Yashiro M, Hirakawa K, et al.
- Journal Title
  
  Journal of Surgical Research 122
  
  Pages: 89-95
- Data Source
  KAKENHI-PROJECT-13470260
[Journal Article] TS-1を含む胃癌の多剤併用療法再発・進行胃癌に対するTS-1+低用量CDDP併用療法2004
- Author(s)
  平川弘聖
- Journal Title
  
  癌と化学療法 31・12
  
  Pages: 1962-1968
- Data Source
  KAKENHI-PROJECT-16209041
[Journal Article] Keratinocyte growth factor produced by gastric fibroblasts specifically stimulates proliferation of cancer cells from scirrhous gastric carcinoma.2003
- Author(s)
  Nakazawa K, Yashiro M, Hirakawa K
- Journal Title
  
  Cancer Res 63
  
  Pages: 8848-8852
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470260
[Patent] TGF-βシグナル阻害剤と抗腫瘍剤の組み合せ使用2007
- Inventor(s)
  片岡一則, 宮園浩平, 狩野光伸, 平川弘聖, 八代正和, 野出學, Bae Younsoo, 西山伸宏
- Industrial Property Rights Holder
  科学技術振興機構
- Industrial Property Number
  2006-024843
- Filing Date
  2007
- Data Source
  KAKENHI-PROJECT-18390369
[Patent] プライマー、腫瘍マーカー、及び癌の検出方法2007
- Inventor(s)
  八代正和, 平川弘聖, 澤田鉄二
- Industrial Property Rights Holder
  財団法人大阪産業振興機構、八代正和,平川弘聖,澤田鉄二
- Filing Date
  2007-05-15
- Data Source
  KAKENHI-PROJECT-18390369
[Patent] tgf-βシグナル阻害剤と抗腫瘍剤の組み合せ使用2006
- Inventor(s)
  片岡一則(東京大学), 宮園浩平(東京大学), 狩野光伸(東京大学), 平川弘聖(大阪市立大学), 八代正和(大阪市立大学), 野出學(京都薬科大学), Bae Younsoo(東京大学), 西山伸宏(東京大学)
- Industrial Property Rights Holder
  科学技術振興機構
- Industrial Property Number
  2006-024843
- Filing Date
  2006-08-30
- Data Source
  KAKENHI-PROJECT-18390369
[Patent] プライマー、腫瘍マーカー、及び癌の検出方法2006
- Inventor(s)
  八代正和, 平川弘聖, 澤田鉄二
- Industrial Property Rights Holder
  財団法人大阪産業振興機構
- Filing Date
  2006
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] 120.CXCL1-CXCR2 Signalling Might Recruit the Bone Marrow-derived Mesenchymal Cells to the Carcinoma-associated Fibroblasts of Gastric Cancer2017
- Author(s)
  Masakazu Yashiro, Tomohisa Okuno, Hiroaki Kasashima, Yuichiro Miki, Hirohisa Nakamae, Kisyu Kitayama, Tsuyoshi Hasegawa, Takahiko Nakane, Masayuki Hino, Kosei Hirakawa
- Organizer
  American Association for Cancer Research 107th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293307
[Presentation] Cancer Stem Cells Might Sustain Stemness by the Induction of Autophagy in Starvation Stress2016
- Author(s)
  Go Masuda, Masakazu Yashiro, Kishu Kitayama, Yuichiro Miki, Hiroaki Kasashima, Tamami Morisaki, Tatsunari Fukuoka, Tsuyoshi Hasegawa, Masaichi Ohira, Kosei Hirakawa
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  New Orleans (USA)
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293307
[Presentation] 1.Significance of an autophagy protein, microtubule-associated protein light chain 3 (LC3), in gastric cancer2015
- Author(s)
  G Masuda, M Yashiro, Hiroaki Kasashima, Haruhito Kinoshita, Tatsunari Fukuoka, Tamami Morisaki, Tsuyoshi Hasegawa, Katsunobu Sakurai, Takahiro Toyokawa, Naoshi Kubo, Hiroaki Tanaka, Kazuya Muguruma, Masaichi Ohira, Hirakawa K.
- Organizer
  American Association for Cancer Research 106th Annual Meeting
- Place of Presentation
  Philadelphia, PA, (USA)
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293307
[Presentation] A c-Met inhibitor increases the chemosensitivity of cancer stem cells to the irinotecan active metabolite SN38 in gastric carcinoma2013
- Author(s)
  Yashiro M, Fukuoka T, Kinoshita H, Nishii T, Hasegawa T, Matsuzaki T, Morisaki T, Hirakawa K
- Organizer
  American Association for Cancer Research 104rd Annual Meeting
- Place of Presentation
  Washington
- Year and Date
  2013-04-07
- Data Source
  KAKENHI-PROJECT-22390262
[Presentation] A c-Met Inhibitor Increases the Chemosensitivity of Cancer Stem Cells to the Irinotecan Active Metabolite SN38 in Gastric Carcinoma2013
- Author(s)
  Masakazu Yashiro, Tatsunari Fukuoka, Haruhito Kinoshita, Takafumi Nishii, Tsuyoshi Hasegawa, Taro Matsuzaki, Tamami Morisaki, Naoshi Kubo, Hiroaki Tanaka, Kazuya Muguruma, Masaichi Ohira, Kosei Hirakawa
- Organizer
  104th AACR Annual meeting
- Place of Presentation
  Washington, D.C. Convention Center
- Data Source
  KAKENHI-PROJECT-22390262
[Presentation] Significance of CXCR4/SDF-1 axis expression in gastric cancer under hypoxic enviroment2013
- Author(s)
  Haruhito Kinoshita, Masakazu Yashiro, Naoshi Kubo,Masaichi Ohira, Kosei Hirakawa
- Organizer
  104th AACR Annual meeting
- Place of Presentation
  Washington, D.C. Convention Center
- Data Source
  KAKENHI-PROJECT-22390262
[Presentation] An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells2012
- Author(s)
  Yashiro M, Fukuoka T, Kinoshita H, Nishii T, Hasegawa T, Matsuzaki T, Morisaki T, Hirakawa K
- Organizer
  American Association for Cancer Research 103rd Annual Meeting.
- Place of Presentation
  Convention Center, Chicago
- Year and Date
  2012-04-04
- Data Source
  KAKENHI-PROJECT-22390262
[Presentation] Effects of VEGFR-3 phosphorylation inhibitor on lymph node metastasis in diffuse-type gastric carcinoma2010
- Author(s)
  Yashiro M, Hirakawa, K.
- Organizer
  AACR
- Place of Presentation
  Washington DC, USA
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-22390262
[Presentation] A novel transforming growth factor beta receptor kinase inhibitor, A-77, prevents the peritoneal dissemination of scirrhous gastric carcinoma2009
- Author(s)
  Yashiro M, Kawajiri H, Shinto O, Nakamura K, Tendo M, Takemura S, Node M, Hamashima Y, Kajimoto T, Sawada T, Ohira M, Hirakawa K.
- Organizer
  100th American Association for Cancer Research
- Place of Presentation
  Denver
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] A novel transforming growth factor β receptor kinase inhibitor, A-77, prevents the peritoneal dissemination of scirrhous gastric carcinoma2009
- Author(s)
  Masakazu Yashiro, Hirakawa K
- Organizer
  100^<th> AACR meeting
- Place of Presentation
  Denver, CO, USA
- Year and Date
  2009-04-20
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] A Novel Molecular Targeting Compound as K-samII/FGFR2 Phosphorylation Inhibitor, Ki23057, for Scirrhous Gastric Cancer2008
- Author(s)
  Yashiro, M, Nakamura, K, Matsuoka, T, Tendo, M, Shimizu, T, Miwa, A, Hirakawa K.
- Organizer
  99th American Association for Cancer Research
- Place of Presentation
  San Diego
- Year and Date
  2008-04-20
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] A Novel Molecular Targeting Compound as K-samII/FGFR2 Phosphorylation Inhibitor, Ki23057, for Scirrhous Gastric Cancer2008
- Author(s)
  Yashiro, M., Nakamura, K., Matsuoka, T., Tendo, M., Shimizu, T., Miwa, A., Hirakawa, K.
- Organizer
  102th American Association for Cancer Research
- Place of Presentation
  San Diego
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] A novel molecular targeting compound as FGF-R2 phosphorylation inhibitor, Ki23057, for scirrhous gastric cancer.2008
- Author(s)
  Yashiro M, Hirakawa, K.
- Organizer
  AACR
- Place of Presentation
  San Diego(USA)
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] Selective cyclooxygenase-2 inhibitor down-regulates the paracrine epithelial-mesenchymal interactions of growth in scirrhous gastric carcinoma2007
- Author(s)
  Yashiro M, Nakazawa, K, Tendo, M, Kosaka, K, Shinto, O, Hirakawa, K.
- Organizer
  98th American Association for Cancer Research
- Place of Presentation
  Los Angels
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] スキルス胃癌進展における病態と分子標的治療2007
- Author(s)
  八代正和、中村和憲、豊川貴弘、井上透、山田靖哉、山下好人、前田清、小野田尚佳、澤田鉄二、仲田文造、加藤保之、大平雅一、石川哲郎、三輪篤史、平川弘聖
- Organizer
  第18回日本消化器癌発生学会総会
- Place of Presentation
  札幌
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] Anti-tumor Effect of Fibroblast Growth Factor Receptor type2 (FGF-R2)Inhibitor On Gastric Cancer Cells2007
- Author(s)
  M. Yashiro, O. Shinto, T. Nishii, K. Nakamura, T. Inoue, A, Miwa, K. Hirakawa
- Organizer
  NEW TARGETS AND DELIVERY SYSTEMS FOR CANCER DIAGNOSIS AND TREATMENT
- Place of Presentation
  San Diego
- Year and Date
  2007-03-06
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] Selective cyclooxygenase-2 inhibitor down-regulates the paracrine epithelial-mesenchymal interactions of growth in scirrhous gastric carcinoma2007
- Author(s)
  Yashiro M, Nakazawa, K., Tendo, M., Kosaka, K., Shinto, O., Hirakawa, K.
- Organizer
  101th American Association for Cancer Research
- Place of Presentation
  Los Angels
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] スキルス胃癌の分子標的治療2007
- Author(s)
  八代正和、中村和憲、川尻成美、神藤理、豊川貴弘、宮園浩平、野出学、梶本哲也、三輪篤史、平川弘聖
- Organizer
  第45回日本癌治療学会総会
- Place of Presentation
  京都
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] FGF-R2/K-samIIおよびTGF-βreceptorを分子標的としたスキルス胃癌転移の治療2007
- Author(s)
  八代正和、川尻成美、神藤理、中村和憲、豊川貴弘、宮園浩平、野出学、梶本哲也、三輪篤史、平川弘聖
- Organizer
  第62回日本消化器外科学会定期学術総会
- Place of Presentation
  東京
- Year and Date
  2007-07-18
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] Selective cyclooxygenase-2 inhibitor downregulates the paracrine epithelial-mesenchymal interactions of growth in scirrhous gastric carcinoma.2007
- Author(s)
  Yashiro M, Hirakawa, K.
- Organizer
  AACR
- Place of Presentation
  Los Angels(USA)
- Year and Date
  2007-04-15
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] スキルス胃癌の分子標的治療2007
- Author(s)
  八代正和、川尻成美、神藤理、井上透、西口幸雄、加藤保之、宮園浩平、野出学、榎本哲也、三輪篤史、平川弘聖
- Organizer
  第79回日本胃癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-03-02
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] Anti-tumor Effect of Fibroblast Growth Factor Receptor type2(FGF-R2)Inhibitor On Gastric Cancer Cells2007
- Author(s)
  MYashiro, OShinto, TNishii, KNakamura, TInoue, A,Miwa, Khirakawa
- Organizer
  New targets and delivery systems for cancer diagnosis and treatment
- Place of Presentation
  San Diego
- Year and Date
  2007-03-10
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] スキルス胃癌の病態と分子標的治2006
- Author(s)
  八代正和、中村和憲、井上透、山田靖哉、西口幸雄、澤田鉄二、大平雅一、前田清、加藤保之、石川哲郎、平川弘聖
- Organizer
  第78回日本胃癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2006-03-11
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] DYSPLASIA-COLITIC CANCER SEQUENCE IN ULCERATIVE COLITIS IS FREQUENTLY ASSOCIATED WITH MICROSATELLITE INSTABILITY PATHWAY.2006
- Author(s)
  M. Yashiro, I. Fujiwara, N Kubo, K. Maeda, K. Hirakawa
- Organizer
  12th International Conference on Ulcer Research (ICUR)
- Place of Presentation
  Osaka
- Year and Date
  2006-07-08
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] Fibroblast growth factor receptor2/K-samIIを分子標的としたスキルス胃癌の治療2006
- Author(s)
  八代正和、中村和憲、平川弘聖
- Organizer
  第48回日本消化器病学会大会
- Place of Presentation
  札幌
- Year and Date
  2006-10-11
- Data Source
  KAKENHI-PROJECT-18390369
[Presentation] TGFβレセプター阻害剤と抗腫瘍剤(S-1)の併用によるスキルス胃癌の新規治療法2006
- Author(s)
  八代正和、川尻成美、平川弘聖
- Organizer
  第48回日本消化器病学会大会
- Place of Presentation
  札幌
- Year and Date
  2006-10-11
- Data Source
  KAKENHI-PROJECT-18390369
[]

1. YASHIRO Masakazu (60305638)

# of Collaborated Projects: 4 results

# of Collaborated Products: 119 results
2. TANIGAWA Nobuhiko (00111956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TAKIUCHI Hiroya (40278528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KUBOTA Testurou (00118944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAO Akimasa (70167542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YAMAUE Hiroki (20191190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 福岡達成

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 森崎珠実

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 木下春人

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 増田剛

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 笠島裕明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 石本崇胤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRAKAWA Kosei 平川 弘聖

CHUNG Yong-Suk 鄭 容錫

〓 容錫 テイ ヨウシヤク

鄭 容錫 テイ ヨウシヤク

Research Projects

Research Products

Co-Researchers

CONQUEST OF THE SCIRRHOUS GASTRIC CANCER: AUTOPHAGY OF CANCER STEM CELLS AND DEVELOPMENT OF MOLECULAR TARGETPrincipal Investigator

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Molecular mechanisms responsible for the development of scirrhous gastric cancer: analysis of cancer stem cells.Principal Investigator

Principal Investigator

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Research Institution

Molecular targeting for scirrhous gastric cancerPrincipal Investigator

Principal Investigator

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Research Institution

In vitro chemosensitivity test to predict chemosensicivity for paclitaxel, using human gastric carcinoma tissues.

Principal Investigator

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Research Institution

Mechanisms responsible for peritoneal metastasis and lymph node metastasis in scirrhous gastric carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

MOLECULAR BIOLOGIC ANALYSIS AND NEW THERAPEUTIC APPROACH IN INVASION AND METASTASIS OF PANCREATIC CANCER.Principal Investigator

Principal Investigator

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New strategy in diagnosis and treatment for pancreatic cancer utilizing monoclonal antibodyPrincipal Investigator

Principal Investigator

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膵癌の診断・治療へのモノクロ-ナル抗体の応用Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Book] 基礎と臨床(曽和融生、井藤久雄編)(スキルス胃癌(新編))2010

Author(s)

Total Pages

Publisher

Data Source

[Book] スキルス胃癌ー基礎と臨床ー(曽和融生、井藤久雄編)2010

Author(s)

Publisher

Data Source

[Journal Article] CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pyruvate kinase isozyme M2 and glutaminase might be promising molecular targets for the treatment of gastric cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells.2017

Author(s)

Journal Title

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[Journal Article] CXCL1-Chemokine (C-X-C Motif) Receptor 2 Signaling Stimulates the Recruitment of Bone Marrow-Derived Mesenchymal Cells into Diffuse-Type Gastric Cancer Stroma.2016

HIRAKAWA Kosei 平川弘聖

CHUNG Yong-Suk 鄭容錫

〓容錫テイヨウシヤク

鄭容錫テイヨウシヤク