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MIYAMOTO Michiko  宮本 道子

ORCIDConnect your ORCID iD *help
Researcher Number 40190821
Affiliation (based on the past Project Information) *help 2005: Tokyo Metropolitan Organization for Medical Research, Tokyo Metropolitan Institute for Neuroscience, Scientist, 研究員
2005: Tokyo Metropolitan Organization for Medical Research, Tokyo Metropolitan Institute for Neuroscience, Scientist, 東京都神経科学総合研究所, 研究員
2002 – 2004: 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 研究員
2003: (財)東京都医学研究機構, 東京都神経科学総合研究所, 研究員
2003: (財)東京都神経科学総合研究所, 主事研究員 … More
2000: Tokyo Metropolitan Institute for Neuroscience, Department of Microbiology and Immunology, Research Scientist, 東京都神経科学総合研究所, 研究員
1999: 財団法人 東京都医学研究機構, 東京都神経科学総合研究所, 主事研究員
1994: Tokyo Metoropolitan Institute for Neurosciences, 微生物学・免疫学, 主任
1994: (財)東京都神経科学総合研究所, 微生物学・免疫学, 主任
1993: (財)東京都神経科学総合研究所, 微生物学・免疫学研究部門, 主事研究員
1992: (財)東京都神経科学総合研究所, 微生物学, 主亊研究員
1992: (財)東京都神経科学総合研究所, 微生物学, 主事研究員
1991: (財)東京都神経科学総合研究所, 微生物学研究部門, 主亊研究員
1990 – 1991: (財)東京都神経科学総合研究所, 微生物学研究部門, 主事研究員
1989: 東京都神経科学総合研究所, 微生物, 主事研究員
1988: (財)東京都神経科学総合研究所, 微生物, 主事研究員
1987: Tokyo Metropolitan Institute for Neurosciences,Research Scientist, 微生物, 主事
1986: (財)東京都神経科学総合研究所, 微生物, 主事 Less
Review Section/Research Field
Principal Investigator
Virology
Except Principal Investigator
Virology / Gastroenterology / Gastroenterology / Virology
Keywords
Principal Investigator
HCV / ウイルス / ウイルスゲノム複製 / 肝臓癌 / 慢性肝炎 / インターフェロン / レプリコン / リバビリン / virus / viral genome replication / HCC / chronic hepatitis / interferon … More
Except Principal Investigator
… More HCV / 日本脳炎ウィルス / 日本脳炎ウイルス / フラビウィルス / E蛋白 / インターフェロン / Japanese encephalitis virus / 組換えウィルス / 進行性多巣性白質脳症 / PML / 調節領域遺伝子 / AIDS / M蛋白 / 神経病原性 / E糖蛋白 / フラビウイルス / JEV / 組換えバキュロウィルス / トランスジェニックマウス / TRANSGENIC MOUSE / CTL / ウイルス / ウイルスゲノム複製 / 肝臓癌 / 慢性肝炎 / HCC / ウィルス構造蛋白 / ウィルスの変異 / ウィルスの病原性 / 蛋白の発現 / JCウイルス / エイズ / JCウィルス / HIV / 制御領域遺伝子 / エンハンサ- / 遺伝子変異 / プロセシング機構 / エンブロープ粒子 / C蛋白 / NS3 / デングウイルス / デング出血熱 / デングショック症候群 / デングウイルス出血熱 / デングウイルス特異的T細胞 / C型肝炎ウイルス / 薬剤感受性 / リバビリン / レプリコンシステム / モノクローナル抗体 / エスケープトミュタント / 新ワクチン / 組換えウイルス / HBsAg粒子 / 粒子 / HBsAg / 新型ワクチン / ワクチン / 抗原構造 / 組換えワクチニアウィルス / E Protein / new vaccine / recombinant virus / Flaviviruses / HBsAg with JEV E / 神経細胞 / 受容体 / prM蛋白 / エンベロープ / E-Mヘテロ2量体 / E蛋白のホモ3量体 / レセプター分子 / 感受性 / 細胞受容体 / preM蛋白 / E蛋白構造 / neurovirulence / neuron / cellular receptor / E protein / prM protein / 発癌 / Cre / loxP / Hepatocarcinogenesis / コア蛋白質 / DNA免疫 / 四塩化炭素 / 慢性肝障害 / 肝発癌 / CCL4 / Heoatocarcinogenesis / virus / viral genome replication / chronic hepatitis / interferon / Virus / Virus replication / Chronic hepatitis / Interferon / 感染防御抗原エピトープ / 単クローン抗体 / 単クローン抗体escaped mutants / E糖蛋白の発現 / コンポーネントワクチン / 感染防御抗原 / エピトープモノクローナル抗体 / 発現ベクター / アミノ酸配列 / GlycoproteinE / Protective epitope / monoclonal antibody / monoclonal antibody escaped mutant / Expression of E protein / recombinant baculovirus Less
  • Research Projects

    (15 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (14 People)
  •  Production and Analysis of Chimeric Hepatitis C Virus

    • Principal Investigator
      DATE Tomoko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      National Institute of Infectious Diseases
      Tokyo Metropolitan Organization for Medical Research
  •  HCVレプリコンシステムを用いた薬剤感受性規定領域の検討

    • Principal Investigator
      加藤 孝宣
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya City University
  •  Viral genomic region of Hepatitis C Virus which determine viral replication and drug sensitivityPrincipal Investigator

    • Principal Investigator
      MIYAMOTO Michiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Analysis of replication of Hepatitis C Virus using highly efficient replication system

    • Principal Investigator
      WAKITA Takaji
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  デングウイルス感染マウスモデルを用いたデング出血熱の病態解析

    • Principal Investigator
      保井 孝太郎
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Construction and analysis of viral hepatocarcinogenesis model using HCV transgenic mouse model

    • Principal Investigator
      WAKITA Takaji
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Construction and analysis of viral hepatocarcinogenesis model using HCV transgenic mouse model

    • Principal Investigator
      WAKITA Takaji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  日本脳炎ウイルス増殖におけるプロセシングとウイルス粒子形成調節機構の解析

    • Principal Investigator
      保井 孝太郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  Analysis of Neurovirulence of Japanese encephalitis virus based on Eprotein-receptor interaction

    • Principal Investigator
      YASUI Kotaro
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      TOKYO METROPOLITAN INSTITUTE FOR NEUROSCIENCES
  •  HIV感染者の産生するJCウイルスの遺伝子構造とPML異常発生との相関

    • Principal Investigator
      保井 孝太郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  フラビウィルス構成蛋白の構造構築のための条件とウィルスの病原性

    • Principal Investigator
      YASUI Kotaro
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  HIV感染者の産生するJCウイルスの遺伝子構造とPML異常発生との相関

    • Principal Investigator
      保井 孝太郎
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  Development of flavivirus vaccine including Japanese encephalitis virus by recombinant DNA technologies

    • Principal Investigator
      YASUI Kotaro
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Virology
    • Research Institution
      Tokyo metropolitan Institute for Neurosciences
  •  日本脳炎ウィルスの神経病原性の研究

    • Principal Investigator
      保井 孝太郎
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tokyo Metropolitan Institute for Neuroscience
  •  Location of Protective Epitopes on the E Protein of Japanese Encephalitis Virus and its Expression

    • Principal Investigator
      YASUI Kotaro
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tokyo Metropolitan Institute for Neurosciences

All 2007 2006 2005 2004

All Journal Article

  • [Journal Article] An infectious and selectable full-length replicon system with hepatitis C virus JFH-1 strain2007

    • Author(s)
      Date T, Miyamoto M, Kato T, Morikawa K, Murayama A, Akazawa D, Tanabe J, Sone S, Mizokami M, Wakita T
    • Journal Title

      Hepatology Research (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590426
  • [Journal Article] CD81 Expression Is Important for Heterogeneous HCV Permissiveness of Huh7 Cell Clones.2007

    • Author(s)
      D Akazawa, T Date, K Morikawa, A Murayama, M Miyamoto, M Kaga, H Barth, T F Baumert, J Dubuisson, T Wakita
    • Journal Title

      J Virol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590426
  • [Journal Article] The Roles of CD81 and glycosaminoglycans in the adsorption and uptake of infectious HCV particles.2007

    • Author(s)
      K Morikawa, Z Zhao, T Date, M Miyamoto, A Murayama, D Akazawa, J Tanabe, S Sone, T Wakita
    • Journal Title

      J. Med. Virol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590426
  • [Journal Article] Characterization of Genotype 2a Hepatitis C Virus Subgenomic Replicon in Comparison with Genotype 1b Replicon2006

    • Author(s)
      M Miyamoto, et al.
    • Journal Title

      Intervirology 49

      Pages: 37-43

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590426
  • [Journal Article] Comparison between Subgenomic Replicons of Hepatitis C Virus Genotype 2a (JFH-1) and 1 b (Con1 NK5.1).2006

    • Author(s)
      M Miyamoto, T Kato, T Date, M Mizokami, T Wakita
    • Journal Title

      Intervirology 49

      Pages: 37-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590426
  • [Journal Article] Characterization of Genotype 2a Hepatitis C Virus Subgenomic Replicon in Comparison with Genotype 1b Replicon.2006

    • Author(s)
      M Miyamoto, T Kato, T Date, M Mizokami, T Wakita.
    • Journal Title

      Intervirology 49

      Pages: 37-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590396
  • [Journal Article] Characterization of Genotype 2a Hepatitis C Virus Subgenomic Replicon in Comparison with Genotype 1b Replicon2006

    • Author(s)
      M Miyamoto, et al.
    • Journal Title

      Intervirology 49

      Pages: 37-43

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590653
  • [Journal Article] Characterization of Genotype 2a Hepatitis C Virus Subgenomic Replicon in Comparison with Genotype 1b Replicon2006

    • Author(s)
      M Miyamoto, et al.
    • Journal Title

      Intervirology 49

      Pages: 37-43

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590396
  • [Journal Article] Characterization of Genotype 2a Hepatitis C Virus Subgenomic Replicon in Comparison with Genotype 1b Replicon.2006

    • Author(s)
      M Miyamoto, T Kato, T Date, M Mizokami, T Wakita.
    • Journal Title

      Intervirology 49

      Pages: 37-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590653
  • [Journal Article] Production of Infectious Hepatitis C Virus in Tissue Culture from a Cloned Viral Genome2005

    • Author(s)
      T Wakita, T Pietschmann, T Kato, T Date, M Miyamoto, Z Zhao, K Murthy, A Habermann, H-G Krausslich, M Mizokami, R Bartenschlager, T J Liang
    • Journal Title

      Nat Med. 11

      Pages: 791-796

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590653
  • [Journal Article] Characterisation of the E-138 (Glu/Lys) mutation in Japanese encephalitis virus using a stable full-length infectious cDNA clone2005

    • Author(s)
      Zhao Z, Date T, Li Y, Kato T, Miyamoto M, Yasui K, Wakita T.
    • Journal Title

      J.Gen.Virol. 86

      Pages: 2209-2220

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590396
  • [Journal Article] Non-Hepatic Cell Lines HeLa and 293 Cells Support Efficient Replication of Hepatitis C Virus Genotype 2a Subgenomic Replicon.2005

    • Author(s)
      T Kato, T Date, M Miyamoto, Z Zho, M Mizokami, T Wakita
    • Journal Title

      Journal of Virology 79

      Pages: 592-596

    • Data Source
      KAKENHI-PROJECT-16590653
  • [Journal Article] Detection of Anti-Hepatitis C Virus Effects of Interferon and Ribavirin by a Sensitive Replicon System2005

    • Author(s)
      T Kato, T Date, M Miyamoto, M Sugiyama, Y Tanaka, E Orito, T Ohno, K Sugihara, I Hasegawa, K Fujiwara, K Ito, A Ozasa, M Mizokami, T Wakita.
    • Journal Title

      Journal of Clinical Microbiology 43

      Pages: 5679-5684

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590653
  • [Journal Article] Detection of Anti-Hepatitis C Virus Effects of Interferon and Ribavirin by a Sensitive Replicon System2005

    • Author(s)
      T Kato, T Date, M Miyamoto, M Sugiyama, Y Tanaka, E Orito, T Ohno, K Sugihara, I Hasegawa, K Fujiwara, K Ito, A Ozasa, M Mizokami, T Wakita.
    • Journal Title

      Journal of Clinical Microbiology 43

      Pages: 5679-5684

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590396
  • [Journal Article] Non-Hepatic Cell Lines HeLa and 293 Cells Support Efficient Replication of Hepatitis C Virus Genotype 2a Subgenomic Replicon.2005

    • Author(s)
      T Kato, T Date, M Miyamoto, Z Zho, M Mizokami, T Wakita
    • Journal Title

      Journal of Virology 79

      Pages: 592-596

    • Data Source
      KAKENHI-PROJECT-16590396
  • [Journal Article] Characterisation of the E-138 (Glu/Lys) mutation in Japanese encephalitis virus using a stable full-length infectious cDNA clone2005

    • Author(s)
      Zhao Z, Date T, Li Y, Kato T, Miyamoto M, Yasui K, Wakita T.
    • Journal Title

      J.Gen.Virol. 86

      Pages: 2209-2220

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590653
  • [Journal Article] Production of Infectious Hepatitis C Virus in Tissue Culture from a Cloned Viral Genome2005

    • Author(s)
      T Wakita, T Pietschmann, T Kato, T Date, M Miyamoto, Z Zhao, K Murthy, A Habermann, H-G Krausslich, M Mizokami, R Bartenschlager, T J Liang
    • Journal Title

      Nat Med. 11

      Pages: 791-796

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590396
  • [Journal Article] Genotype 2a Hepatitis C Virus Subgenomic Replicon Can Replicate in HepG2 and IMY-N9 cells2004

    • Author(s)
      Date T, Kato T, Miyamoto M, Zhao Z, Yasui K, Mizokami M, Wakita T
    • Journal Title

      Journal of Biological Chemistry 279

      Pages: 22371-22376

    • Data Source
      KAKENHI-PROJECT-16590396
  • [Journal Article] Genotype 2a Hepatitis C Virus Subgenomic Replicon Can Replicate in HepG2 and IMY-N9 cells2004

    • Author(s)
      Date T, Kato T, Miyamoto M, Zhao Z, Yasui K, Mizokami M, Wakita T
    • Journal Title

      Journal of Biological Chemistry 279

      Pages: 22371-22376

    • Data Source
      KAKENHI-PROJECT-16590653
  • [Journal Article] Difference of Hepatitis C Virus Core Protein Processing between Genotypes 1 and 2.2004

    • Author(s)
      T Kato, M Miyamoto, T Date, A Furusaka, M Mizokami, T Wakita
    • Journal Title

      Hepatology Research 30

      Pages: 204-209

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590396
  • [Journal Article] Difference of Hepatitis C Virus Core Protein Processing between Genotypes 1 and 2.2004

    • Author(s)
      T Kato, M Miyamoto, T Date, A Furusaka, M Mizokami, T Wakita
    • Journal Title

      Hepatology Research 30

      Pages: 204-209

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590653
  • 1.  YASUI Kotaro (90073080)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  KIMURA-KURODA Junko (20142151)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  WAKITA Takaji (40280789)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 18 results
  • 4.  KATO Takanobu (20333370)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 14 results
  • 5.  OGIMOTO Mami (80158609)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  SUGAMATA Masami (00091041)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  TAKEGAMI Tsutomu (10113490)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KOJIMA Asato (30100077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MATSUURA Yoshiharu (50157252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KOHARA Michinori (10250218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  DATE Tomoko (40392360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 12.  MURAYAMA Asako (40415534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 13.  松田 道行 (10199812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  溝上 雅史 (40166038)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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