TAKAHASHI Ryoya 高橋良哉

… Alternative Names

高橋良哉タカハシリヨウヤ

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Researcher Number	40197190
Other IDs
Affiliation (Current)	2025: 東邦大学, 薬学部, 名誉教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 東邦大学, 薬学部, 教授 2007 – 2008: Toho University, 薬学部, 教授 2006: 東邦大学, 薬学部, 助教授 1992 – 1994: 東邦大学, 薬学部, 助手 1988 – 1989: 東邦大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Environmental physiology (including Physical medicine and Nutritional physiology) / Biological pharmacy Except Principal Investigator Biological pharmacy / 老化(加齢)
Keywords	Principal Investigator 老化 / 熱ショックタンパク質 / プロテオスタシス / タンパク質品質管理 / タンパク質分解 / プロテアソーム / 異常タンパク質 / 肝臓 / プロテオーム / 離乳 … More / 老化促進モデルマウス / 成長 / 発達 / HSP90 / HSP70 / 脳 / 加齢 / 老化促進マウス / ストレス蛋白質 / 熱ショック蛋白質 … More Except Principal Investigator 肝実質細胞 / 蛋白質分解 / 老化 / Protein Degradation / Altered enzyme / Aging / 活性酸素 / 異常酵素 / 酸化タンパク質 / インスリン / タンパク質分解 / タンパク質分解半減期 / 酸化修飾タンパク質 / 脳 / インスリン分解酵素 / プロテアソーム / 蛋白質酸化傷害 Less

中高齢期から始まるタンパク質品質管理システムの破綻に関する研究Principal Investigator
- Principal Investigator
  
  高橋良哉
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Toho University
INVESTIGATION OF THE MECHANISMS OF ACCELERATED AGING AFTER WEANING IN SENESCENCE ACCELELATED MOUSE P8 STRAINPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Ryoya
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Toho University
老化に伴う脳神経系におけるストレス蛋白質遺伝子発現の変化Principal Investigator
- Principal Investigator
  
  高橋良哉
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University
加齢に伴う蛋白質分解活性低下の分子機構
- Principal Investigator
  
  GOTO Sataro (後藤佐多良)
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  老化(加齢)
- Research Institution
  Toho University
Biochemical studies on the mechanism of Generation and accumulation of altered enzymes with age
- Principal Investigator
  
  GOTO Sataro
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toho University, School of Pharmaceutical Science

All 2023 2022 2021 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] 老化・老年病研究のための動物実験ガイドブック2008
- Author(s)
  高橋良哉
- Publisher
  アドスリー
- Data Source
  KAKENHI-PROJECT-18590224
[Journal Article] Direct Fluorescence Evaluation of d-Amino Acid Oxidase Activity Using a Synthetic d-Kynurenine Derivative2022
- Author(s)
  Tatsuya Sakamoto, Keiko Odera, Mayu Onozato, Hiroshi Sugasawa, Ryoya Takahashi, Yasuto Fujimaki, and Takeshi Fukushima
- Journal Title
  
  Analytical Chemistry
  
  Volume: 94 Issue: 42 Pages: 14530-14536
- DOI
  10.1021/acs.analchem.2c00775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11710, KAKENHI-PROJECT-20K11540
[Journal Article] Beneficial biochemical outcomes of late-onset dietary restriction in rodents2007
- Author(s)
  Sataro Goto, Ryoya Takahashi, Zsolt Radak, Ramesh Sharma
- Journal Title
  
  Annals of the New York Academy of Sciences 1100
  
  Pages: 431-441
- Data Source
  KAKENHI-PROJECT-18590224
[Journal Article] Effect of dietary restriction on learning and memory impairment and histologic alterations of brain stem in senescence-accelerated mouse (SAM) P8 strain.2006
- Author(s)
  Ryoya Takahashi
- Journal Title
  
  Annals of the New York Academy of Sciences 1067
  
  Pages: 388-393
- Data Source
  KAKENHI-PROJECT-18590224
[Presentation] 老化基礎研究からの情報発信：種差・性差.2023
- Author(s)
  高橋良哉, 大寺恵子
- Organizer
  日本薬学会第143年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] Uptake and degradation of fluorescent dye-labeled albumin in the renal proximal tubular cells of young and old rats2023
- Author(s)
  Keiko Odera, Ryoya Takahashi
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] 生細胞内で発生する次亜塩素酸イオンの検出と可視化2023
- Author(s)
  大寺恵子, Richa Yadav, Abhishek Rai, 野口明実, Lallan Mishra, 高橋良哉
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] Dysfunction of protein homeostasis with age: Alteration of proteasomes in rat liver2023
- Author(s)
  Ryoya Takahashi, Keiko Odera
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] Protein Homeostasis (Proteostasis): Effect of Age on Protein Repair and Degradation Systems.2022
- Author(s)
  Ryoya Takahashi, Keiko Odera
- Organizer
  International Symposium on "Recent Advances in Research on Healthy Aging and Future Challenges" and 20th Biennial Meeting of Association of Gerontology (India)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] 加齢に伴うラットおよびマウスの肝のプロテアソーム活性変化.2022
- Author(s)
  高橋良哉、大寺恵子
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] ラットとマウスの肝プロテアソームの加齢変化の比較.2022
- Author(s)
  高橋良哉, 大寺恵子
- Organizer
  第45回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] Effect of fasting-refeeding on the levels of glycogen and triglyceride in the liver of SAMP8 and SAMR1.2021
- Author(s)
  Ryoya Takahashi, Keiko Odera
- Organizer
  第44回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] Intestinal distribution pattern of fatty acid binding proteins in SAMP8 and SAMR1.2021
- Author(s)
  Keiko Odera, Ryoya Takahashi
- Organizer
  第44回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] Dietary Restriction from Late Adulthood can Improve Biomolecular Damages Associated with Aging.2021
- Author(s)
  Ryoya Takahashi
- Organizer
  27th International Conference (CONIAPS XXVII) on Interdisciplinary Research in Biomedical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11710
[Presentation] 老化促進モデルマウスSAMを用いた抗老化研究2009
- Author(s)
  高橋良哉
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-18590224
[Presentation] 老化促進モデルマウスSAMを用いた抗老化研究2009
- Author(s)
  高橋良哉
- Organizer
  日本薬学会第129年会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-18590224
[Presentation] Altered expression of myelin basic protein gene in the cerebellum of SAMP8 mice2008
- Author(s)
  高橋良哉
- Organizer
  第31回日本基礎老化学会
- Place of Presentation
  松本
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-18590224
[Presentation] 離乳期SAMP8小脳におけるミエリン塩基性タンパク遺伝子発現異常2008
- Author(s)
  高橋良哉
- Organizer
  第23回老化促進モデルマウス(SAM)研究協議会研究発表会
- Place of Presentation
  京都
- Year and Date
  2008-07-17
- Data Source
  KAKENHI-PROJECT-18590224
[Presentation] Effect of late-life dietary restriction on the accumulation of oxidative damages2007
- Author(s)
  Ryoya Takahashi
- Organizer
  8th Asia/Oceania Regional Congress of Gerontology and Geriatrics
- Place of Presentation
  Beijing, Chaina
- Year and Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-18590224
[Presentation] Effect of dietary restriction initiated from old on the activities of cathepsins and albumin degradation in the kidney of rats.2007
- Author(s)
  Ryoya Takahashi
- Organizer
  American Aging Association-36th Annual Meeting
- Place of Presentation
  Texas, USA
- Year and Date
  2007-06-02
- Data Source
  KAKENHI-PROJECT-18590224
[Presentation] Effect of dietary restriction initiated from old on age-related alteration of endocytic receptors megalin and cubilin in the kidney of rats. American Aging2007
- Author(s)
  Ryoya Takahashi
- Organizer
  American Aging Association-36th Annual Meeting
- Place of Presentation
  Texas, USA
- Year and Date
  2007-06-02
- Data Source
  KAKENHI-PROJECT-18590224

1. GOTO Sataro (10012650)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. MOTOJIMA Kiyoto (70166338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKAHASHI Ryoya 高橋 良哉

高橋 良哉 タカハシ リヨウヤ

Research Projects

Research Products

Co-Researchers

中高齢期から始まるタンパク質品質管理システムの破綻に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

INVESTIGATION OF THE MECHANISMS OF ACCELERATED AGING AFTER WEANING IN SENESCENCE ACCELELATED MOUSE P8 STRAINPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

老化に伴う脳神経系におけるストレス蛋白質遺伝子発現の変化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

加齢に伴う蛋白質分解活性低下の分子機構

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biochemical studies on the mechanism of Generation and accumulation of altered enzymes with age

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 老化・老年病研究のための動物実験ガイドブック2008

Author(s)

Publisher

Data Source

[Journal Article] Direct Fluorescence Evaluation of d-Amino Acid Oxidase Activity Using a Synthetic d-Kynurenine Derivative2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Beneficial biochemical outcomes of late-onset dietary restriction in rodents2007

Author(s)

Journal Title

Data Source

[Journal Article] Effect of dietary restriction on learning and memory impairment and histologic alterations of brain stem in senescence-accelerated mouse (SAM) P8 strain.2006

Author(s)

Journal Title

Data Source

[Presentation] 老化基礎研究からの情報発信：種差・性差.2023

Author(s)

Organizer

Data Source

[Presentation] Uptake and degradation of fluorescent dye-labeled albumin in the renal proximal tubular cells of young and old rats2023

Author(s)

Organizer

Data Source

[Presentation] 生細胞内で発生する次亜塩素酸イオンの検出と可視化2023

Author(s)

Organizer

Data Source

[Presentation] Dysfunction of protein homeostasis with age: Alteration of proteasomes in rat liver2023

Author(s)

Organizer

Data Source

[Presentation] Protein Homeostasis (Proteostasis): Effect of Age on Protein Repair and Degradation Systems.2022

Author(s)

Organizer

Data Source

[Presentation] 加齢に伴うラットおよびマウスの肝のプロテアソーム活性変化.2022

Author(s)

Organizer

Data Source

[Presentation] ラットとマウスの肝プロテアソームの加齢変化の比較.2022

Author(s)

Organizer

Data Source

TAKAHASHI Ryoya 高橋良哉

高橋良哉タカハシリヨウヤ