Yonemochi Etsuo 米持悦生

… Alternative Names

YONEMOCHI Etsuo 米持悦生

Less

Researcher Number	40201090
Other IDs
External Links
Affiliation (Current)	2025: 国際医療福祉大学, 成田薬学部, 教授
Affiliation (based on the past Project Information) *help	2024: 国際医療福祉大学, 成田薬学部, 教授 2014 – 2016: 星薬科大学, 薬学部, 教授 1995 – 1996: 千葉大学, 薬学部, 助手 1991 – 1992: 千葉大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Physical pharmacy Except Principal Investigator Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Keywords	Principal Investigator 正電荷ナノプレックス / 正電荷リポプレックス / コレステロール誘導体 / MADG / ITC / 小角散乱 / ナノ粒子 / リポプレックス / 等温滴定型カロリメトリー / 小角X線散乱測定 … More / 脂質ナノ粒子 / 安定性 / 凍結乾燥 / 等温滴定型力ロリメトリー / 小角Ｘ線散乱 / siRNA / 脂質ナノ粒子複合体 … More Except Principal Investigator molecular interaction / mechanochemistry / 包接化合物 / 非晶質 / 分子間相互作用 / 中分子薬物 / 安定性 / 吸収性 / ナノ粒子 / porous / enantiotropic / cholic acid / sealed-heating / crystal / pharmaceutics / 熱分析 / 密封加熱法 / 溶出 / 非晶質化 / 粉末X線回折 / 固形製剤 / コール酸 / 多孔性 / 光学活性 / コール電子 / 密封加熱 / メカノケシストリー / 結晶 / 製剤工学 / solid dispersion / infrared spectrum / fluorescence / crystallinity / inclusion / cyclodextrin / メカノケミストリ- / 固体分散系 / 赤外吸収スペクトル / 蛍光スペクトル / 結晶性 / 包接 / シクロデキストリン / メカノケミストリー Less

Elucidation of destabilization mechanism of drug amorphous nanosuspension for middle-molecule drug development
- Principal Investigator
  
  東顕二郎
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Chiba University
Study on solid formulation of lipoplex using ionic liquidPrincipal Investigator
- Principal Investigator
  
  Yonemochi Etsuo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Hoshi University
Analysis of Molecular Interactions in Solid Pharmaceuticals
- Principal Investigator
  
  YAMAMOTO Keiji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Chiba University
A Study of Mechanochemical Effects on the Solid Dispersion of Pharmaceuticals and Molecular Interactions
- Principal Investigator
  
  YAMAMOTO Keiji
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Chiba University

All 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Molecular Dynamics of Amorphous Sulfamethazine With Structurally Related Sulfonamide Impurities Evaluated Using Thermal Analysis.2017
- Author(s)
  Y. Hamada, M. Ono, M. Ohara, E. Yonemochi
- Journal Title
  
  J. Pharm. Sci.
  
  Volume: 106 Issue: 4 Pages: 1062-1068
- DOI
  10.1016/j.xphs.2016.12.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460048
[Journal Article] Isostructural Multicomponent Gliclazide Crystals with Improved Solubility2016
- Author(s)
  O. D. Putra, E. Yonemochi, H. Uekusa
- Journal Title
  
  Crystal Growth & Design
  
  Volume: 16 Issue: 11 Pages: 6568-6573
- DOI
  10.1021/acs.cgd.6b01279
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460048
[Journal Article] Crystal Structure Determination of Dimenhydrinate after More than 60 Years: Solving Salt-Cocrystal Ambiguity via Solid-State Crystal2016
- Author(s)
  O. D. Putra, T. Yoshida, D. Umeda, K. Higashi, H. Uekusa, E. Yonemochi
- Journal Title
  
  Crystal Growth & Design
  
  Volume: 16 Issue: 9 Pages: 5223-5229
- DOI
  10.1021/acs.cgd.6b00771
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460048
[Journal Article] Tumor delivery of liposomal doxorubicin prepared with poly-L-glutamic acid as a drug-trapping agent2016
- Author(s)
  Andang Miatmoko, Kumi Kawano, Hitomi Yoda, Etsuo Yonemochi, Yoshiyuki Hattori
- Journal Title
  
  Journal of Liposome Research
  
  Volume: 27 Issue: 2 Pages: 1-9
- DOI
  10.3109/08982104.2016.1166511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460048
[Journal Article] The effect of structurally related impurities on crystallinity reduction of sulfamethazine by grinding2016
- Author(s)
  Y. Hamada, M. Ono, M. Ohara, E. Yonemochi
- Journal Title
  
  Int. J. Pharm.
  
  Volume: 515 Issue: 1-2 Pages: 416-421
- DOI
  10.1016/j.ijpharm.2016.09.069
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460048
[Journal Article] The effect of water activity on granule characteristics and tablet properties produced by moisture activated dry granulation (MADG)2016
- Author(s)
  Hiroshi Takasaki, Etsuo Yonemochi, Masanori Ito, Koichi Wada, Katsuhide Terada
- Journal Title
  
  Powder Technology
  
  Volume: 294 Pages: 113-118
- DOI
  10.1016/j.powtec.2016.02.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460048
[Journal Article] Drug-drug multicomponent crystals as an effective technique to overcome weaknesses in parent drugs2016
- Author(s)
  O. D. Putra, T. Furuishi, E. Yonemochi, K. Terada, H. Uekusa
- Journal Title
  
  Crystal Growth & Design
  
  Volume: 16 Issue: 7 Pages: 3577-3581
- DOI
  10.1021/acs.cgd.6b00639
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460048
[Journal Article] Crystallographic Analysis of Phase Dissociation Related to Anomalous Solubility of Irsogladine Maleate2016
- Author(s)
  O. D. Putra, T. Yoshida, D. Umeda, M. Gunji, E. Yonemochi, H. Uekus
- Journal Title
  
  Crystal Growth & Design
  
  Volume: 16 Issue: 12 Pages: 6714-6718
- DOI
  10.1021/acs.cgd.6b01356
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460048
[Journal Article] siRNA Delivery into Tumor Cells by Cationic Cholesterol Derivative Based Nanoparticles and Liposomes2015
- Author(s)
  Yoshiyuki Hattori, Eriko Hara Yumiko Shingu, Daiki Minamiguchi, Ayako Nakamuraj, Shohei Araij Hiroaki Ohno, Kumi Kawano, Nobutaka Fujii, and Etsuo Yonemochi
- Journal Title
  
  Ｂｉｏｌ．　Ｐｈａｒｍ．　Ｂｕｌｌ．
  
  Volume: 38 Pages: 30-38
- NAID
  130004872237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460048
[Journal Article] The importanceofbindermoisturecontentinMetforminHCL high-dose formulationspreparedbymoistaqueousgranulation(MAG)2015
- Author(s)
  HiroshiTakasaki, Etsuo Yonemochi, Masanori Ito, Koichi Wada, KatsuhideTerada
- Journal Title
  
  ResultsinPharmaSciences
  
  Volume: 5 Pages: 1-7
- DOI
  10.1016/j.rinphs.2015.09.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460048
[Presentation] 正電荷リポソーム/siRNA複合体形成メカニズムの検討2017
- Author(s)
  新庄永治、高村宏平、村越南実、片山捷平、郡司美穂子、古石誉之、福澤薫、米持悦生
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460048
[Presentation] 正電荷リポソームとsiRNAによる複合体の分子構造の解明2017
- Author(s)
  高村宏平、遠藤朋宏、郡司美穂子、古石誉之、福澤薫、米持悦生
- Organizer
  日本薬剤学会第32年会
- Place of Presentation
  大宮
- Year and Date
  2017-05-11
- Data Source
  KAKENHI-PROJECT-26460048
[Presentation] Structural Characterizations and Physicochemical Evaluations of Pharmaceutical Co-Crystal Epalerstat-Caffeine2016
- Author(s)
  D. Umeda, M. Gunji, H. Nagase, T. Furuishi, O. D. Putra, H. Uekusa, E. Yonemochi
- Organizer
  14th Conference of Asian Crystallographic Association
- Place of Presentation
  Hanoi, Vietnam
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460048
[Presentation] 有機酸－メグルミンの新規分子複合体の基礎的特性2016
- Author(s)
  古石誉之, 浅野美咲季, 高崎宏, 和田耕一, 郡司美穂子, 遠藤朋宏，米持悦生
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460048
[Presentation] 小角X線散乱測定による正電荷リポソームとsiRNAのリポプレックス形成過程の検討2016
- Author(s)
  米持悦生、木村高暢、Andang Miatmoko、菊池拓人、川野久美、服部喜之、郡司美穂子、古石誉之、遠藤朋宏
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460048
[Presentation] ポリグルタミン酸と正電荷リポプレックスの連続投与は肝臓ならびに肝臓転移がんに対してsiRNAによる遺伝子発現抑制を誘導する
- Author(s)
  新井翔平，服部喜之，岡本遼，濱田めぐみ，川野久美，米持悦生
- Organizer
  第30回日本ＤＤＳ学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-26460048
[Presentation] 負電荷ポリマーと正電荷リポプレックスの連続投与による肝臓へのsiRNA送達における負電荷ポリマーの種類と正電荷リポプレックスの荷電比の最適化
- Author(s)
  岡本遼，服部喜之，新井翔平，濱田めぐみ，川野久美，米持悦生
- Organizer
  第30回日本ＤＤＳ学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-26460048
[Presentation] 肝臓へsiRNAを送達するための負電荷ポリマー溶液と正電荷リポプレックスの連続投与法の開発
- Author(s)
  新井翔平，服部喜之，岡本遼，濱田めぐみ，川野久美，米持悦生
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-26460048

1. YAMAMOTO Keiji (50110341)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. OGUCHI Toshio (30169255)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HATTORI Yoshiyuki (90350222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. KAWANO Kumi (20366834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. NAKAJIMA Shinichiro (80009175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 東顕二郎 (40451760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 森部久仁一 (50266350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 植田圭祐 (40755972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 福澤薫 (50718244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yonemochi Etsuo 米持 悦生

YONEMOCHI Etsuo 米持 悦生

Research Projects

Research Products

Co-Researchers

Elucidation of destabilization mechanism of drug amorphous nanosuspension for middle-molecule drug development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on solid formulation of lipoplex using ionic liquidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Molecular Interactions in Solid Pharmaceuticals

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Study of Mechanochemical Effects on the Solid Dispersion of Pharmaceuticals and Molecular Interactions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Molecular Dynamics of Amorphous Sulfamethazine With Structurally Related Sulfonamide Impurities Evaluated Using Thermal Analysis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isostructural Multicomponent Gliclazide Crystals with Improved Solubility2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal Structure Determination of Dimenhydrinate after More than 60 Years: Solving Salt-Cocrystal Ambiguity via Solid-State Crystal2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor delivery of liposomal doxorubicin prepared with poly-L-glutamic acid as a drug-trapping agent2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effect of structurally related impurities on crystallinity reduction of sulfamethazine by grinding2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effect of water activity on granule characteristics and tablet properties produced by moisture activated dry granulation (MADG)2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Drug-drug multicomponent crystals as an effective technique to overcome weaknesses in parent drugs2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystallographic Analysis of Phase Dissociation Related to Anomalous Solubility of Irsogladine Maleate2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] siRNA Delivery into Tumor Cells by Cationic Cholesterol Derivative Based Nanoparticles and Liposomes2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The importanceofbindermoisturecontentinMetforminHCL high-dose formulationspreparedbymoistaqueousgranulation(MAG)2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 正電荷リポソーム/siRNA複合体形成メカニズムの検討2017

Yonemochi Etsuo 米持悦生

YONEMOCHI Etsuo 米持悦生