Okada Shoshiro 岡田尚志郎

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OKADA Shoshiro 岡田尚志郎

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Researcher Number	40203989
Other IDs
Affiliation (Current)	2025: 愛知医科大学, 愛知医科大学, 名誉教授 2025: 日本医科大学, 大学院医学研究科, 研究生
Affiliation (based on the past Project Information) *help	2023: 日本医科大学, 大学院医学研究科, 研究生 2011 – 2022: 愛知医科大学, 医学部, 教授 2009 – 2010: Kochi University, 教育研究部・医療学系, 准教授 2008: Kochi University, 教育研究部医療学系, 准教授 2005 – 2006: 高知大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related / General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine) Except Principal Investigator General internal medicine(including psychosomatic medicine) / Basic Section 52030:Psychiatry-related / Laboratory medicine
Keywords	Principal Investigator 視床下部室傍核 / トロンボキサンA2 / 拘束ストレス / アドレナリン受容体 / 室傍核 / ノルアドレナリン / CRF / cFos / 血中カテコールアミン / 2型糖尿病 … More / うつ病 / ホスホリパーゼC / 脳内ノルアドレナリン神経系 / プロスタグランジンE2 / GABA神経細胞 / ATP感受性K+チャネル / SU薬 / ミノサイクリン / AAV ベクター / カテコールアミン / ノックダウン / トロンボキサン受容体 / AAV / プロスタノイド / 交感神経系 / ストレス / CRF1 receptor / nicotinic receptor α3 subunit / corticotropin releasing factor (CRF) / noradrenaline / locus coeruleus / hypothalamic paraventricular nucleus / c-FOS / コルチゾール / ニューロサーキット / α_3β_2ニコチン受容体 / ニコチン受容体 / インドメタシン / コルチコステロン / ワルアドレナリン / 橋背外側被蓋核 / 青斑核 / 血糖値 / 血中カテコラミン / PPARγ / presympathetic neuron / restraint stress / plasma catecholamine / PPAR gamma / preautonomic neuron / hypothalamic PVN / 副腎髄質系賦活 / PLC / α1アドレノセプター / 生活習慣病 / 副腎髄質系 / NMDA受容体 / トロンボキサン / アドレノセプター / ノルアドレナリン神経系 / NMDA … More Except Principal Investigator ストレス / 室傍核 / カテコールアミン / 交感神経系 / CRF / コルチコトロピン放出因子 / 視床下部室傍核 / HPA系 / LC-ITMSn / マイクロダイアリシス / PVN / プロスタノイド / 神経伝達物質 / 中枢性エネルギー枯渇 / アドレナリン / 慢性炎症 / 性差 / 高齢 Less

Roles of brain thromboxane A2 in the major depression-related disorder of glucose metabolismPrincipal Investigator
- Principal Investigator
  
  岡田尚志郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nippon Medical School
  Aichi Medical University
Central mechanisms for continuous responses of sympathetic nervous system to stress exposure
- Principal Investigator
  
  YAMAGUCHI Naoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Aichi Medical University
Is the connection between noradrenergic nervous system and CRF in the hypothalamic paraventricular nucleus involved in the sustained-stress responses?Principal Investigator
- Principal Investigator
  
  Okada Shoshiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Aichi Medical University
CRF-related mechanism of stress responses in the rat brain
- Principal Investigator
  
  YAMAGUCHI Naoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Aichi Medical University
中枢性副腎髄質系賦活に関与する視床下部室傍核の灌流液中生理活性物質の網羅的解析
- Principal Investigator
  
  近藤文雄
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Aichi Medical University
Roles for PPAR gamma in the hypothalamic PVN in the catecholamin secretion from adrenal medulla in ratsPrincipal Investigator
- Principal Investigator
  
  OKADA shoshiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Aichi Medical University
たこつぼ心筋症の成因に関する研究-糖代謝・炎症を機軸とした中枢神経系の関与
- Principal Investigator
  
  公文義雄
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kochi University
Role of alpha1 adrenoceptor activation in the hypothalamic paraventricular nucleus on the adrenomedullary outflow in ratsPrincipal Investigator
- Principal Investigator
  
  OKADA Shoshiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kochi University
Is the hypothalamic paraventricular nucleus-locus coeruleus neuronal circuit involved in persistent increase in the plasma cortisol?Principal Investigator
- Principal Investigator
  
  OKADA Shoshiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kochi University

[Journal Article] Isolation of the Anti-Inflammatory Agent Myceliostatin from a Methionine-Enriched Culture of <i>Myceliophthora thermophila</i> ATCC 424642023
- Author(s)
  Wu Yanhua、Shen Junfeng、Wang Liyan、Lin Yinzhi、Kojima Shiori、Okada Shoshiro、Umezawa Kazuo
- Journal Title
  
  Journal of Natural Products
  
  Volume: 86 Issue: 2 Pages: 239-245
- DOI
  10.1021/acs.jnatprod.2c00811
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24323, KAKENHI-PROJECT-21K07531
[Journal Article] Yokukansan, a Traditional Japanese Medicine, Suppresses Stress-Induced Sympathetic Activation via Central Responses in Rats2023
- Author(s)
  Naoko Yamaguchi, Kenta Maruyama, Shoshiro Okada
- Journal Title
  
  Natural Product Communications
  
  Volume: 18 Issue: 11 Pages: 1-11
- DOI
  10.1177/1934578x231203085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07531, KAKENHI-PROJECT-23K07046
[Journal Article] Practices and challenges of joint education at two medical schools utilizing online pharmacology role-playing2023
- Author(s)
  岡田尚志郎，近藤一直，山口奈緒子，一瀬千穂，柳田俊彦
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 158 Issue: 2 Pages: 134-137
- DOI
  10.1254/fpj.22069
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21531, KAKENHI-PROJECT-21K07531
[Journal Article] Glucose infusion suppresses acute restraint stress-induced peripheral and central sympathetic responses in rats.2022
- Author(s)
  Yamaguchi N, Kakinuma Y, Yakura T, Naito M, Okada S.
- Journal Title
  
  Auton. Neurosci.
  
  Volume: 239 Pages: 102957-102957
- DOI
  10.1016/j.autneu.2022.102957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07982, KAKENHI-PROJECT-21K07531
[Journal Article] Thromboxane A2 in the paraventricular hypothalamic nucleus mediates glucoprivation-induced adrenomedullary outflow.2020
- Author(s)
  Tachi M, Yamaguchi N, Okada S.
- Journal Title
  
  Eur. J. Pharmacol.
  
  Volume: 875 Pages: 173034-173034
- DOI
  10.1016/j.ejphar.2020.173034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07982
[Journal Article] Clostridium butyricum Modulates the Microbiome to Protect Intestinal Barrier Function in Mice with Antibiotic-Induced Dysbiosis2020
- Author(s)
  Hagihara M.、Kuroki Y.、Ariyoshi T.、Higashi S.、Fukuda K.、Yamashita R.、Matsumoto A.、Mori T.、Mimura K.、Yamaguchi N.、Okada S.、Nonogaki T.、Ogawa T.、Iwasaki K.、Tomono S.、Asai N.、Koizumi Y.、Oka K.、Yamagishi Y.、Takahashi M.、Mikamo H.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 1 Pages: 100772-100772
- DOI
  10.1016/j.isci.2019.100772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05898, KAKENHI-PROJECT-17K09331, KAKENHI-PROJECT-17K11209
[Journal Article] Prostaglandin E2 receptor EP3 subtype in the paraventricular hypothalamic nucleus mediates corticotropin-releasing factor-induced elevation of plasma noradrenaline levels in rats.2019
- Author(s)
  Yamaguchi N, Mimura K, Okada S.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 863 Pages: 172693-172693
- DOI
  10.1016/j.ejphar.2019.172693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09331
[Journal Article] Isolation of ketomycin from Actinomycetes as an inhibitor of 2D and 3D cancer cell invasion.2019
- Author(s)
  Lin Y, Chen Y, Ukaji T, Okada S, Umezawa K.
- Journal Title
  
  J Antibiot (Tokyo).
  
  Volume: 72(3) Issue: 3 Pages: 148-154
- DOI
  10.1038/s41429-018-0129-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09331
[Journal Article] GABAB receptors in the hypothalamic paraventricular nucleus mediate β-adrenoceptor-induced elevations of plasma noradrenaline in rats.2019
- Author(s)
  Yamaguchi N, Mimura K, Okada S.
- Journal Title
  
  Eur. J. Pharmacol.
  
  Volume: 848 Pages: 88-95
- DOI
  10.1016/j.ejphar.2019.01.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09269, KAKENHI-PROJECT-17K09331
[Journal Article] CRFによる交感神経系活性化における視床下部室傍核アドレナリン受容体の役割2018
- Author(s)
  山口奈緒子, 岡田尚志郎
- Journal Title
  
  自律神経
  
  Volume: 55 Pages: 295-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09331
[Journal Article] Changes in hypothalamic neurotransmitter and prostanoid levels in response to NMDA, CRF, and GLP-1 stimulation2015
- Author(s)
  Fumio Kondo, Masahiko Tachi, Masahiko Gosho, Minoru Fukayama, Kazuhiro Yoshikawa, Shoshiro Okada
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: 407 Issue: 18 Pages: 5261-5272
- DOI
  10.1007/s00216-015-8496-6
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08939
[Journal Article] Centrally administered isoproterenol induces sympathetic outflow via brain prostaglandin E2-mediated mechanisms in rats.2015
- Author(s)
  Ando K, Kondo F, Yamaguchi N, Tachi M, Fukayama M, Yoshikawa K, Gosho M, Fujiwara Y, Okada S.
- Journal Title
  
  Auton Neurosci.
  
  Volume: 189 Pages: 1-7
- DOI
  10.1016/j.autneu.2014.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590903, KAKENHI-PROJECT-25460901
[Journal Article] Mass spectrometric determination of prostanoids in rat hypothalamic paraventricular nucleus microdialysates.2014
- Author(s)
  Tachi M, Kondo F, Fukayama M, Yoshikawa K, Matsuura K, Okada S
- Journal Title
  
  Auton Neurosci.
  
  Volume: 181 Pages: 49-54
- DOI
  10.1016/j.autneu.2013.12.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590903
[Journal Article] Enhanced expression of WD repeat-containing protein 35 via nuclear factor-kappa B activation in bupivacaine-treated Neuro2a cells.2014
- Author(s)
  Huang L, Kondo F, Harato M, Feng GG, Ishikawa N, Fujiwara Y, Okada S.
- Journal Title
  
  PLoS One
  
  Volume: 9(1) Issue: 1 Pages: e86336-e86336
- DOI
  10.1371/journal.pone.0086336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592689, KAKENHI-PROJECT-24590903
[Journal Article] Bupivacaine-induced apoptosis independently of WDR35 expression in mouse neuroblastoma Neuro2a cells.2013
- Author(s)
  Harato M, Huang L, Kondo F, Tsunekawa K, Feng GG, Fan JH, Ishikawa N, Fujiwara Y, Okada S.
- Journal Title
  
  BMC Neurosci.
  
  Volume: - Issue: 1 Pages: 149-149
- DOI
  10.1186/1471-2202-13-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592689, KAKENHI-PROJECT-23790885, KAKENHI-PROJECT-24590903
[Journal Article] High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles2013
- Author(s)
  Takuma Higuchi
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 8 Pages: e43340-e43340
- DOI
  10.1371/journal.pone.0043340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10660, KAKENHI-PROJECT-12J10665, KAKENHI-PUBLICLY-23118515, KAKENHI-PROJECT-23390068, KAKENHI-PROJECT-23590979, KAKENHI-PROJECT-24590903
[Journal Article] The human female heart incorporates glucose more efficiently than the male heart.2013
- Author(s)
  Kakinuma Y, Okada S, Nogami M, Kumon Y
- Journal Title
  
  Int J Cardiol.
  
  Volume: 168 Issue: 3 Pages: 2518-2521
- DOI
  10.1016/j.ijcard.2013.03.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590903
[Journal Article] Enhanced expression of WD repeat-containing protein 35 (WDR35) stimulated by domoic acid in rat hippocampus: involvement of reactive oxygen species generation and p38 mitogen-activated protein kinase activation.2013
- Author(s)
  Tsunekawa K, Kondo F, Okada T, Feng GG, Huang L, Ishikawa N, Okada S.
- Journal Title
  
  BMC Neurosci.
  
  Volume: - Issue: 1 Pages: 4-4
- DOI
  10.1186/1471-2202-14-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592689, KAKENHI-PROJECT-23790885, KAKENHI-PROJECT-24590903
[Journal Article] Systemic inflammation impairs cardiac glucose uptake.2012
- Author(s)
  Kakinuma Y, Okada S, Nogami M, Sano S, Kumon Y.
- Journal Title
  
  Int J Cardiol.
  
  Volume: 154(2) Pages: 203-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590678
[Journal Article] Role of naofen in apoptosis of hepatocytes induced by lipopolysaccharide through mitochondrial signaling in rats.2012
- Author(s)
  Fan JH, Feng GG, Huang L, Tsunekawa K, Honda T, Katano Y, Hirooka Y, Goto H, Kandatsu N, Ando K, Fujiwara Y, Koide T, Okada S, Ishikawa N.
- Journal Title
  
  Hepatol Res.
  
  Volume: 42 Issue: 7 Pages: 696-705
- DOI
  10.1111/j.1872-034x.2012.00972.x
- NAID
  10031144286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592689, KAKENHI-PROJECT-23790885, KAKENHI-PROJECT-24590903
[Journal Article] Systemic inflammation impairs cardiac glucose uptake.2012
- Author(s)
  Kakinuma Y, Okada S, Nogami M, Sano S, Kumon Y.
- Journal Title
  
  Int J Cardiol
  
  Volume: 154 Issue: 2 Pages: 203-204
- DOI
  10.1016/j.ijcard.2011.10.066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590903
[Journal Article] Microbial degradation of physiologically active peptides by strain B-9.2012
- Author(s)
  Kondo F, Okada S, Miyachi A, Kurita M, Tsuji K, Harada K.
- Journal Title
  
  Anal Bioanal Chem.
  
  Volume: 403 Issue: 7 Pages: 1783-1791
- DOI
  10.1007/s00216-011-5635-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590903
[Journal Article] Alphal-adrenoceptor activation is involved in the central N-methyl-D-aspartate-induced adrenomedullary outflow in rats.2010
- Author(s)
  Okada S, Yamaguchi N.
- Journal Title
  
  Eur.J.Pharmacol. 640
  
  Pages: 55-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591370
[Journal Article] α1-Adrenoceptor activation is involved in the central N-methyl-D-aspartate-induced adrenomedullary outflow in rats2010
- Author(s)
  Okada S, Yamaguchi N
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 640 Pages: 55-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591370
[Journal Article] Cyclooxygenase and nitric oxide synthase in the presympathetic neurons in the paraventricular hypothalamic nucleus are involved in restraint stress-induced sympathetic activation in rats2010
- Author(s)
  Yamaguchi N, Ogawa S, Okada S
- Journal Title
  
  Neuroscience
  
  Volume: 170 Pages: 773-781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591370
[Journal Article] Cyclooxygenase-1 and -2 in spinally projecting neurons are involved in CRF-induced sympathetic activation2009
- Author(s)
  Yamaguchi N, Okada S
- Journal Title
  
  Autonomic Neuroscience 151
  
  Pages: 82-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591370
[Journal Article] Nitric oxide synthase isozymes in spinally projecting neurons are involved in CRF-induced sympathetic activation2009
- Author(s)
  N Yamaguchi, S Okada, D Usui, K Yokotani
- Journal Title
  
  Autonomic Neuroscience : Basic and Clinical (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591370
[Journal Article] Nitric oxide synthase isozymes in spinally projecting PVN neurons are involved in CRF-induced sympathetic activation.2009
- Author(s)
  Yamaguchi N, Okada S, Usui D, Yokotani K.
- Journal Title
  
  Auton. Neurosci. 148
  
  Pages: 83-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591370
[Journal Article] Cyclooxygenase-1 and -2 in spinally projecting neurons are involved in CRF-induced sympathetic activation.2009
- Author(s)
  Yamaguchi N, Okada S.
- Journal Title
  
  Auton.Neurosci. 151
  
  Pages: 82-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591370
[Journal Article] Adrenal adrenaline- and noradrenaline-containing cells and celiac ganglia are differentially controlled by centrally administered corticotropin-releasing factor and arginine-vasopressin in rats2007
- Author(s)
  N Yamaguch-Shima, S Okada, T Shimizu, D Usui, K Nakamura, L Lu, K Yokotani
- Journal Title
  
  European Journal of Pharmacology 564
  
  Pages: 94-102
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591217
[Journal Article] Adrenal adrenaline-and noradrenaline-containing cells and celiac sympathetic ganglia differentially controlled by centrally administered corticotropin-releasing factor and arginine-vasopressin in rats,2007
- Author(s)
  N Yamaguchi-Shima, S Okada, T Shimizu, D Usui, K Nakamura, L Lu, K Yokotani
- Journal Title
  
  European Journal of Pharmacology 564
  
  Pages: 94-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591217
[Journal Article] 視床下部ー下垂体ー副腎皮質系賦活における脳内CRF含有神経およびコリン作動性神経の役割2005
- Author(s)
  岡田尚志郎
- Journal Title
  
  ACTH RELATED PEPTIDES 16
  
  Pages: 63-69
- Data Source
  KAKENHI-PROJECT-17591217
[Journal Article] Estrogen is involved in improvement of impaired cardiac glucose uptake in cancer patients
- Author(s)
  Yoshihiko Kakinuma, Shoshiro Okada, Nobuo Ikenoue, Munenobu Nogami, Yoshitaka Kumon
- Journal Title
  
  Journal of Cardiology Cases
  
  Volume: (in press)(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590678
[Presentation] 抑肝散投与は拘束ストレスによる交感神経系活性化を抑制する2022
- Author(s)
  山口奈緒子、藤川誠、岡田尚志郎
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K07531
[Presentation] Yokukansan, a traditional Japanese medicine, suppresses stress-induced sympathetic activation and central responses to stress in rats.2022
- Author(s)
  Yamaguchi N, Fujikawa M, Okada S.
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07982
[Presentation] 室傍核アストロサイトは脳内コルチコトロピン放出因子による交感神経系活性化に関与する2022
- Author(s)
  山口奈緒子　岡田尚志郎
- Organizer
  日本薬理理学会
- Data Source
  KAKENHI-PROJECT-21K07531
[Presentation] Astrocytes in the PVN are involved in corticotropin-releasing factor-induced sympathetic activation in rats.2022
- Author(s)
  Yamaguchi N, Okada S.
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07982
[Presentation] 脳内ATP感受性カリウムチャネル活性化は血中アドレナリン増加に関与する2022
- Author(s)
  岡田尚志郎　山口奈緒子
- Organizer
  日本薬理理学会
- Data Source
  KAKENHI-PROJECT-21K07531
[Presentation] ATP-sensitive K+ channel activation in the brain is involved in elevation of plasma levels of adrenaline.2022
- Author(s)
  Okada S, Yamaguchi N.
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07982
[Presentation] Prostaglandin E2 EP3 receptor subtype in the paraventricular hypothalamic nucleus mediates the corticotropin-releasing factor-induced elevation of plasma noradrenaline level in rats.2019
- Author(s)
  Yamaguchi N, Mimura Ｍ, Okada S.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K09269
[Presentation] ストレスによる血中カテコールアミン遊離・分泌の中枢性調節2019
- Author(s)
  岡田尚志郎
- Organizer
  第84回日本温泉気候物理医学会総会・学術集会（岡山）
- Invited
- Data Source
  KAKENHI-PROJECT-17K09331
[Presentation] グルコース投与によるストレス誘導性交感神経系活性化の抑制 Glucose infusion inhibits restraint stress-induced sympathetic activation in rats.2019
- Author(s)
  山口奈緒子, 柿沼由彦, 三村郁, 矢倉富子, 内藤宗和, 岡田尚志郎
- Organizer
  第42回日本神経科学大会・第62回日本神経化学会大会（NEURO2019)（新潟）
- Data Source
  KAKENHI-PROJECT-17K09331
[Presentation] Thromboxane A2 in the paraventricular nucleus of the hypothalamus participates in 2-deoxyglucose-induced sympathetic activation in freely moving rats.2019
- Author(s)
  Shoshiro Okada, Masahiko Tachi, Naoko Yamaguchi.
- Organizer
  Annual Meeting of the Society for Neuroscience (Neuroscience 2019). Chicago, IL, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09331
[Presentation] プロスタグランジンE2は視床下部室傍核のEP3受容体サブタイプを介してCRFによる血中ノルアドレナリン増加を調節する2019
- Author(s)
  山口奈緒子、三村郁、岡田尚志郎
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K09331
[Presentation] GABAB receptor in the hypothalamic paraventricular nucleus mediates β-adrenoceptor activation-induced elevation of plasma noradrenaline in rats.2018
- Author(s)
  Yamaguchi N, Mimura K, Okada S.
- Organizer
  18th World congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09269
[Presentation] GABAB receptor in the hypothalamic paraventricular nucleus mediates β-adrenoceptor activation-induced elevation of plasma noradrenaline in rats2018
- Author(s)
  Yamaguchi N, Mimura K, Okada S.
- Organizer
  第91回日本薬理学会年会 , 第18回国際薬理学・臨床薬理学会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09331
[Presentation] Differential roles of adrenoceptors in the hypothalamic paraventricular nucleus in corticotropin-releasing factor-induced sympathetic activation in rats.2017
- Author(s)
  Yamaguchi N, Sano K, Okada S.
- Organizer
  第70回日本自律神経学会総会
- Data Source
  KAKENHI-PROJECT-17K09331
[Presentation] Differential roles of adrenoceptors in the hypothalamic paraventricular nucleus in corticotropin-releasing factor-induced sympathetic activation in rats.2017
- Author(s)
  Yamaguchi N, Sano K, Okada S.
- Organizer
  第70回日本自律神経学会総会
- Data Source
  KAKENHI-PROJECT-16K09269
[Presentation] Possible role of adrenoceptors in the hypothalamic paraventricular nucleus in corticotropin-releasing factor-induced sympathetic activation in rats.2017
- Author(s)
  Yamaguchi N, Mimura K, Okada S.
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール・長崎新聞文化ホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K09269
[Presentation] 自由行動下におけるラット視床下部室傍核灌流液中プロスタノイドの分析2014
- Author(s)
  舘昌彦　近藤文雄　深山実　吉川和宏　松浦克彦　岡田尚志郎
- Organizer
  第８７回日本薬理学会年会
- Place of Presentation
  仙台（東北大学）
- Data Source
  KAKENHI-PROJECT-24590903
[Presentation] ラット視床下部室傍核灌流液中の神経伝達物質及びプロスタノイドの同時モニタリング2014
- Author(s)
  近藤文雄　舘昌彦　深山実　吉川和宏　岡田尚志郎
- Organizer
  第８７回日本薬理学会年会
- Place of Presentation
  仙台（東北大学）
- Data Source
  KAKENHI-PROJECT-24590903
[Presentation] AMPKはbupivacaine処理Neuro2a細胞におけるWDR35の発現に関与する2014
- Author(s)
  黄磊、近藤文雄、馮国剛、藤澤明子、石川直久、岡田尚志郎
- Organizer
  第８７回日本薬理学会年会
- Place of Presentation
  仙台（東北大学）
- Data Source
  KAKENHI-PROJECT-24590903
[Presentation] NF κBはWDR35の発現に関与する2014
- Author(s)
  馮国剛、黄磊、石川直久、近藤文雄、岡田尚志郎
- Organizer
  第８７回日本薬理学会年会
- Place of Presentation
  仙台（東北大学）
- Data Source
  KAKENHI-PROJECT-24590903
[Presentation] Bupivacaine処理Neuro2a細胞におけるWDR３５に対するNF-κBの関与2013
- Author(s)
  黄磊、近藤文雄、馮国剛、恒川幸司、石川直久、岡田尚志郎
- Organizer
  第８６回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24590903
[Presentation] LPSを投与したラット肝細胞のアポトーシスに対するプロポフォールの保護作用2013
- Author(s)
  馮国剛、神立伸久、黄磊、近藤文雄、藤原祥裕、岡田尚志郎
- Organizer
  第８６回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24590903
[Presentation] ラット視床下部室傍核潅流液中プロスタノイドの質量分析法による測定2013
- Author(s)
  舘昌彦、近藤文雄、深山実、吉川和宏、岡田尚志郎
- Organizer
  第８６回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24590903
[Presentation] 脳室内投与したCRFは脳内α1アドレナリン作動性受容体の賦活を介して交感神経一副腎髄質系を賦活する2010
- Author(s)
  岡田尚志郎, 山口奈緒子
- Organizer
  日本薬理学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] 脳室内投与したCRFは脳内α1アドレナリン作動性受容体の賦活を介して交感神経-副腎髄質系を賦活する2010
- Author(s)
  岡田尚志郎、山口奈緒子
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] 拘束ストレスによる血中カテコールアミン増加におけるPPAR gammaの役割2010
- Author(s)
  岡田尚志郎、山口奈緒子
- Organizer
  Neuro 2010(日本神経科学会)
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] 拘束ストレス負荷による血中カテコラミン増加におけるPPAR gammaの役割2010
- Author(s)
  岡田尚志郎、山口奈緒子
- Organizer
  Neuro 2010(第33回日本神経科学会)
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] 拘束ストレス負荷による血中カテコラミン増加の基盤となる脳内機構の薬理学的解析2010
- Author(s)
  岡田尚志郎、山口奈緒子
- Organizer
  第63回日本自律神経学会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] NMDAによる中枢性副腎髄質系賦活におけるPLCの役割2009
- Author(s)
  岡田尚志郎、山口奈緒子
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] NMDAによる中枢性副腎髄質系賦活におけるPLCの役割2009
- Author(s)
  岡田尚志郎, 山口奈緒子
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  神奈川県・横浜パシフィコ
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] 脳室内投与したCRFによる交感神経-副腎髄質系賦活機構における脳内アドレナリン作動性受容体の役割2009
- Author(s)
  岡田尚志郎、山口奈緒子
- Organizer
  第62回日本自律神経学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] 拘束ストレス負荷による血中カテコールアミン増加における脳内炎症関連メディエーターの役割2009
- Author(s)
  岡田尚志郎、山口奈緒子
- Organizer
  第32回日本神経科学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] 脳室内投与したNMDAによる副腎髄質系賦活機構の薬理学的解析2008
- Author(s)
  岡田尚志郎、山口奈緒子、清水孝洋、横谷邦彦
- Organizer
  第61回日本自律神経学会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-20591370
[Presentation] 脳室内投与したイソプロテレノールはGABAb受容体の賦活を介して血中ノルアドレナリンを増加させる
- Author(s)
  三村郁、安藤一雄、山口奈緒子、近藤文雄、舘昌彦、藤原祥裕、岡田尚志郎
- Organizer
  第８８回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24590903
[Presentation] 2ーDGは脳内プロスタノイド依存性に視床下部室傍核ノルアドレナリン遊離および血中カテコラミンを増加させる
- Author(s)
  舘昌彦、近藤文雄、山口奈緒子、深山実、吉川和宏、岡田尚志郎
- Organizer
  第８８回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24590903

1. YAMAGUCHI Naoko (50380324)

# of Collaborated Projects: 5 results

# of Collaborated Products: 22 results
2. 呉ユー秋 (40717154)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 公文義雄 (40215033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 柿沼由彦 (40233944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 津田雅之 (90406182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 杉浦哲朗 (50171145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 近藤文雄 (40450861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 舘昌彦 (60744274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 馮国剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
10. 本多隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 伴野勧

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okada Shoshiro 岡田 尚志郎

OKADA Shoshiro 岡田 尚志郎

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Roles of brain thromboxane A2 in the major depression-related disorder of glucose metabolismPrincipal Investigator

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Central mechanisms for continuous responses of sympathetic nervous system to stress exposure

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Is the connection between noradrenergic nervous system and CRF in the hypothalamic paraventricular nucleus involved in the sustained-stress responses?Principal Investigator

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CRF-related mechanism of stress responses in the rat brain

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中枢性副腎髄質系賦活に関与する視床下部室傍核の灌流液中生理活性物質の網羅的解析

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Roles for PPAR gamma in the hypothalamic PVN in the catecholamin secretion from adrenal medulla in ratsPrincipal Investigator

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たこつぼ心筋症の成因に関する研究-糖代謝・炎症を機軸とした中枢神経系の関与

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Role of alpha1 adrenoceptor activation in the hypothalamic paraventricular nucleus on the adrenomedullary outflow in ratsPrincipal Investigator

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Is the hypothalamic paraventricular nucleus-locus coeruleus neuronal circuit involved in persistent increase in the plasma cortisol?Principal Investigator

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[Journal Article] Isolation of the Anti-Inflammatory Agent Myceliostatin from a Methionine-Enriched Culture of <i>Myceliophthora thermophila</i> ATCC 424642023

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[Journal Article] Yokukansan, a Traditional Japanese Medicine, Suppresses Stress-Induced Sympathetic Activation via Central Responses in Rats2023

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[Journal Article] Practices and challenges of joint education at two medical schools utilizing online pharmacology role-playing2023

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[Journal Article] Glucose infusion suppresses acute restraint stress-induced peripheral and central sympathetic responses in rats.2022

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Okada Shoshiro 岡田尚志郎

OKADA Shoshiro 岡田尚志郎