KOBAYASHI Seneki 小林千益

Researcher Number	40205464
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007: 信州大学, 医学部, 准教授 2001 – 2006: Shinshu University, Medical School, Associate Professor, 医学部, 助教授 2000: 信州大学, 医学部・付属病院, 講師 1999 – 2000: 信州大学, 医学部, 講師 1997: Shinshu University, School of Medicine, Assistant Professor, 医学部附属病院, 助手 … More 1995 – 1997: 信州大学, 医学部・附属病院, 助手 1994 – 1995: 信州大学, 医学部附属病院, 助手 1991: 信州大学, 医学部・附属病院(整形外科), 助手 1991: Shinshu University, School of Medicine, Assistant, 医学部附属病院(整形外科), 助手 1990: 信州大学, 医上部・附属病院・整形外科, 助手 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery
Keywords	Principal Investigator ウサギ / 変形性関節症 / 最表層 / 関節軟骨 / 膝関節 / proteoglycan / lubrication / rabbit / surface layr / knee joint … More / osteoarthrosis / articular cartilage / プロテオグリカン / 潤滑 / Experimental osteoarthrosis / Subchondral bone / Rabbit / Osteoarthrosis / Surface layr / Articular cartilage / 実験的関節症 / 軟骨下骨 / 股関節 / モニタリング / 合併症 / 耐用性 / 全国的登録システム / 人工股関節置換術 / 人口膝関節置換術 / 計測誤差 / ポリエチレン摩耗 / 放射線学 / X線像 / 人工膝関節置換術 / 骨代謝 / 骨粗鬆症 / メカニカルストレス / ステロイド / 大腿骨頭壊死症 … More Except Principal Investigator サイトカイン / 人工関節 / 生体分解性ポリマー / ドラッグデリバリーシステム / 担体 / Lamina splendens / 骨髄単核球細胞 / デリバリーシステム / 骨組織再生 / biodegradable polymer / mononuclear cell / cytokine / biomaterial / drug delivery system / bone tissue repair / prosthesis for arthroplasty / bone morphogenetic protein / 組織工学 / 組織再生 / 再生医療 / 骨欠損 / 生体材料 / DDS / 骨組織修復 / 骨形成タンパク / Bone / Hip prosthesis / Biodegradable polymer / Drug delivery system / Carrier / Bone morphogenetic protein / 骨 / 骨形成因子 / Enzymatic digestion / Biomechanics / Joint / Ultrastructure / Histrology / Articular cartilage / Cryo-scanning electron microscope / 力学的特性 / 酵素 / 組織学 / lamina splendens / 酵素消化 / 生体力学 / 関節 / 微細構造 / 組繊学 / 関節軟骨 / 凍結走査電子顕微鏡 / 大腿骨頭壊死 / 血管再生 / 細胞移植 / 骨髓単核球細胞 / 大腿骨頭壞死 Less

骨髄単核球細胞移植を用いた大腿骨頭壊死症に対する新しい治療技術の開発
- Principal Investigator
  
  齋藤直人 (斎藤直人)
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
人工股関節置換術の合併症と耐用性をモニタリングする登録システムの企画調査:合併症防止と長期耐用性向上をめざしてPrincipal Investigator
- Principal Investigator
  
  小林千益
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
人工膝関節ポリエチレン摩耗のコンピューターX線計測システム開発Principal Investigator
- Principal Investigator
  
  小林千益
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
Development of new prostheses for arthroplasty with an added ability to promote bone repair using bone morphogenetic protein (BMP)
- Principal Investigator
  
  SAITO Naoto
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
New type of prosthesis combined with rhBMP-2 delivery system
- Principal Investigator
  
  SAITO Naoto
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
特発性大腿骨頭壊死症の発生機序と予防と治療に関する骨代謝学的研究Principal Investigator
- Principal Investigator
  
  小林千益
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
Study on the pathogenesis of osteoarthrosis secondary to scraping the surface of the articular cartilage : with special interest on the importance of the surface layr of the articular cartilagePrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Seneki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
Study on relationship between the surface amorphous layr of the articular cartilage and pathogenesis of osteoarthrosisPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Seneki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
Cryo-scanning electron microscopic study on mechanical and structural characteristics of the superficial zone of the articular cartilagePrincipal Investigator
- Principal Investigator
  
  FUJIOKA Fumio, 小林千益
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University

All 2005 2004 2003 2002 2001

All Journal Article

[Journal Article] A anew method of measuring polyethylene wear in press fit condylar total knee arthroplasty on standard standing radiographs I : evaluation of accuracy.2005
- Author(s)
  Kobayashi S, 他5名
- Journal Title
  
  J Arthroplasty 20(発表予定)
- Data Source
  KAKENHI-PROJECT-14657362
[Journal Article] A new method of measuring polyethylene wear in press fit condylar total knee arthroplasty on standard standing radiographs II : evaluation of clinical efficacy.2005
- Author(s)
  Kobayashi S, 他5名
- Journal Title
  
  J Arthroplasty 20(発表予定)
- Data Source
  KAKENHI-PROJECT-14657362
[Journal Article] E nhancement of recombinant human bone morphogenetic protein-2 (rhbmp-2)-induced new bone formation by concurrent treatment with parathyroid hormone and a phosphodiesterase inhibitor, pentoxifylline2004
- Author(s)
  Horiuchi H, Nawata M, Kamijo T, Saito N, Wakitani S, Kobayashi S, Shimizu T, Kato H
- Journal Title
  
  J Bone Miner Metab 22
  
  Pages: 329-334
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Continuous local cooling for pain relief following total hip arthroplasty.2004
- Author(s)
  Saito N, Horiuchi H, Kobayashi S, Nawata M, Takaoka K.
- Journal Title
  
  J Arthroplasty 19
  
  Pages: 334-337
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Total hip arthroplasty with bulk femoral head autograft for acetabular reconstruction in DDH : surgical technique.2004
- Author(s)
  Kobayashi S, Saito N, Nawata M, Horiuchi H, Iorio R, Takaoka K.
- Journal Title
  
  J Bone Joint Surg Am 83 Suppl 1
  
  Pages: 11-17
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Total hip arthroplasty with bulk femoral head autograft for acetabular reconstruction in DDH : surgical technique.2004
- Author(s)
  Kobayashi S, Saito N, Nawata M, Horiuchi H, Iorio R, Takaoka K.
- Journal Title
  
  J Bone Joint Surg Am 86 Supple 1
  
  Pages: 11-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Continuous local cooling for pain relief following total hip arthroplasty2004
- Author(s)
  Saito N, Horiuchi H, Kobayashi S, Nawata M, Takaoka K
- Journal Title
  
  J Arthroplasty
  
  Pages: 334-337
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] THAのポイント : Charnley型人工股関節置換術 : 大腿骨側の処理2004
- Author(s)
  小林千益, 斎藤直人, 堀内博志, 加藤博之
- Journal Title
  
  関節外科 23(4)Supple
  
  Pages: 16-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] セメントレス大腿骨ステムの長期成績 : omnifitとomniflex間での比較2004
- Author(s)
  天正恵治, 小林千益, 斎藤直人, 堀内博志, 加藤博之
- Journal Title
  
  中部整災誌 47(4)
  
  Pages: 641-642
- NAID
  10013748237
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Total hip arthroplasty with bulk femoral head autograft for acetabular reconstruction in DDH : surgical technique2004
- Author(s)
  Kobayashi S, Saito N, Nawata M, Horiuchi H, Iorio R, Takaoka K
- Journal Title
  
  J Bone Joint Surg Am 83 Supple 1
  
  Pages: 11-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Osteoprotegerin regulates bone formation through a coupling mechanism with bone resorption.2003
- Author(s)
  Nakamura M, Udagawa N, Matsuura S, Mogi M, Nakamura H, Horiuchi H, Saito N, Hiraoka Y, Kobayashi Y, Takaoka K, Ozawa H, Miyazawa H, Takahashi N.
- Journal Title
  
  Endocrinology 144
  
  Pages: 5441-5449
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Trabecular minimodeling in human iliac bone.2003
- Author(s)
  Kobayashi S, Takahashi HE, Ito A, Saito N, Nawata M, Horiuchi H, Ohta H, Ito A, Iorio R, Yamamoto N, Takaoka K.
- Journal Title
  
  Bone 32
  
  Pages: 163-169
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Total hip arthroplasty with bulk femoral head autograft for acetabular reconstruction in developmental dysplasia of the hip2003
- Author(s)
  Kobayashi S, Saito N, Nawata M, Horiuchi H, Iorio R, Takaoka K
- Journal Title
  
  J Bone Joint Surg Am 85
  
  Pages: 615-621
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Trabecular minimodeling in human iliac bone2003
- Author(s)
  Kobayashi S, Takahashi HE, Ito A, Saito N, Nawata M, Horiuchi H, Ohta H, Ito A, Iorio R, Yamamoto N, Takaoka K
- Journal Title
  
  Bone 32
  
  Pages: 163-169
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Total hip arthroplasty with bulk femoral head autograft for acetabular reconstruction in developmental dysplasia of the hip.2003
- Author(s)
  Kobayashi S, Saito N, Nawata M, Horiuchi H, Iorio R, Takaoka K.
- Journal Title
  
  J Bone Joint Surg Am 85
  
  Pages: 615-621
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Sequential changes in periprosthetic bone mineral density following total hip arthroplasty : a 3-year follow-up2003
- Author(s)
  Ohta H, Kobayashi S, Saito N, Nawata M, Horiuchi H, Takaoka K
- Journal Title
  
  J Bone Miner Metab 21
  
  Pages: 229-233
- NAID
  10014444735
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Osteoprotegerin regulates bone formation through a coupling mechanism with bone resorption2003
- Author(s)
  Nakamura M, Udagawa N, Matsuura S, Mogi M, Nakamura H, Horiuchi H, Saito N, Hiraoka Y, Kobayashi Y, Takaoka K, Ozawa H, Miyazawa H, Takahashi N
- Journal Title
  
  Endocrinology 144
  
  Pages: 5441-5449
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] PFC人工膝関節置換術後立位X線前後像での脛骨側ポリエチレンライナー厚計測の試み2002
- Author(s)
  小林千益, 斎藤直人, 縄田昌司, 堀内博志, 太田浩史, 高岡邦夫
- Journal Title
  
  膝 26
  
  Pages: 195-198
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] Three-dimentional computed tomography evaluation of bony birth canal morphologic deformity (small pelvic cavity) after dome pelvic osteotomy for developmental dysplasia of the hip.2002
- Author(s)
  Kojima S, Kobayashi S, Saito N, Nawata M, Horiuchi H, Takaoka K.
- Journal Title
  
  Am J Obstet Gynecol 187
  
  Pages: 1591-1595
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] A vascular necrosis of the femoral head in Fabry's disease : identification of ceramide trihexoside in the bone by delayed extraction matrix-assisted laser desorption ionization time-of-flight mass sectromtry : a case report.2002
- Author(s)
  Horiuchi H, Saito N, Kobayashi S, Ota H, Taketomi T, Takaoka K.
- Journal Title
  
  Arth Rheum/Ar C Res 46
  
  Pages: 1922-1925
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] オプテトラック人工膝関節置換術とPFC人工膝関節置換術のROMの比較2002
- Author(s)
  大島和也, 小林千益, 斎藤直人, 縄田昌司, 堀内博志, 太田浩史, 高岡邦夫, 吉村康夫
- Journal Title
  
  日本人工関節学会誌 32
  
  Pages: 143-144
- NAID
  10012751506
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] オプテトラック人工膝関節置換術とPFC人工膝関節置換術のROMの比較2002
- Author(s)
  大島和也, 小林千益, 高岡邦夫
- Journal Title
  
  中部整災誌 45
  
  Pages: 827-828
- NAID
  10012751506
- Data Source
  KAKENHI-PROJECT-14657362
[Journal Article] Three-dimentional computed tomography evaluation of bony birth canal morphologic deformity (small pelvic cavity) after dome pelvic osteotomy for developmental dysplasia of the hip2002
- Author(s)
  Kojima S, Kobayashi S, Saito N, Nawata M, Horiuchi H, Takaoka K
- Journal Title
  
  Am J Obstet Gynecol 187
  
  Pages: 1591-1595
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] PFC人工膝関節置換術後立位X線前後像での脛骨側ポリエチレンライナー厚計測の試み2002
- Author(s)
  小林千益, 小林千益, 斎藤直人, 繩田昌司, 堀内博志, 太田浩史, 高岡邦夫
- Journal Title
  
  膝 26
  
  Pages: 195-198
- Data Source
  KAKENHI-PROJECT-14657362
[Journal Article] A vascular necrosis of the femoral head in Fabry's disease : identification of ceramide trihexoside in the bone by delayed extraction matrix-assisted laser desorption ionization time-of-flight mass sectromtry : a case report2002
- Author(s)
  Horiuchi H, Saito N, Kobayashi S, Ota H, Taketomi T, Takaoka K
- Journal Title
  
  Arth Rheum/Ar C Res 46
  
  Pages: 1922-1925
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370459
[Journal Article] PFC人工膝関節置換術の術後成績2001
- Author(s)
  小林千益, 繩田昌司, 堀内博志, 齋藤直人, 太田浩史, 大鶴聡, 高岡邦夫, 丸山正昭
- Journal Title
  
  日本人工膝関節学会誌 31
  
  Pages: 35-36
- Data Source
  KAKENHI-PROJECT-14657362
[Journal Article] PFC人工膝関節ポリエチレンライナー厚のX線計測法の精度:in vitroでの検討2001
- Author(s)
  小林千益, 斎藤直人, 繩田昌司, 堀内博志, 高岡邦夫
- Journal Title
  
  中部整災誌 44
  
  Pages: 1379-1380
- NAID
  10009770715
- Data Source
  KAKENHI-PROJECT-14657362

1. SAITO Naoto (80283258)

# of Collaborated Projects: 5 results

# of Collaborated Products: 24 results
2. TAKAOKA Kunio (30112048)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
3. MURAKAMI Narumichi (50334892)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIMIZU Tominaga (40283270)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 堀内博志 (80377639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. FUJIOKA Fumio (00209024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KINOSHITA Hisatoshi (30177894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAHASHI Jun (60345741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 縄田昌司 (70324259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 樋口富士男 (60131778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 大園健二 (90168930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 菅野伸彦 (70273620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 進藤裕幸 (30107677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 山本卓明 (20336035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 加藤博之 (40204490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 池田宇一 (30221063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 高橋将文 (40296108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小平博之 (40419362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 谷川浩隆 (40262711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOBAYASHI Seneki 小林 千益

Research Projects

Research Products

Co-Researchers

骨髄単核球細胞移植を用いた大腿骨頭壊死症に対する新しい治療技術の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

人工股関節置換術の合併症と耐用性をモニタリングする登録システムの企画調査:合併症防止と長期耐用性向上をめざしてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

人工膝関節ポリエチレン摩耗のコンピューターX線計測システム開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new prostheses for arthroplasty with an added ability to promote bone repair using bone morphogenetic protein (BMP)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New type of prosthesis combined with rhBMP-2 delivery system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

特発性大腿骨頭壊死症の発生機序と予防と治療に関する骨代謝学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the pathogenesis of osteoarthrosis secondary to scraping the surface of the articular cartilage : with special interest on the importance of the surface layr of the articular cartilagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on relationship between the surface amorphous layr of the articular cartilage and pathogenesis of osteoarthrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cryo-scanning electron microscopic study on mechanical and structural characteristics of the superficial zone of the articular cartilagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A anew method of measuring polyethylene wear in press fit condylar total knee arthroplasty on standard standing radiographs I : evaluation of accuracy.2005

Author(s)

Journal Title

Data Source

[Journal Article] A new method of measuring polyethylene wear in press fit condylar total knee arthroplasty on standard standing radiographs II : evaluation of clinical efficacy.2005

Author(s)

Journal Title

Data Source

[Journal Article] E nhancement of recombinant human bone morphogenetic protein-2 (rhbmp-2)-induced new bone formation by concurrent treatment with parathyroid hormone and a phosphodiesterase inhibitor, pentoxifylline2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Continuous local cooling for pain relief following total hip arthroplasty.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Total hip arthroplasty with bulk femoral head autograft for acetabular reconstruction in DDH : surgical technique.2004

Author(s)

Journal Title

Data Source

KOBAYASHI Seneki 小林千益