Yorozu Tomoko 萬知子

Researcher Number	40210801
Other IDs
Affiliation (Current)	2025: 杏林大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2013 – 2024: 杏林大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Medical and hospital managemen / Basic Section 58010:Medical management and medical sociology-related Except Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology
Keywords	Principal Investigator 集中治療室 / サーベイランス / 血流感染症 / 中心静脈カテーテル / 感染関連因子 / 予防策 / カテーテル関連血流感染症 / 集中治療 / 医療安全 / 感染防御 … More / 中心静脈カテーテル感染 / データ収集システム / 病院管理 / 感染予防 / 院内感染 / 感染防止介入策 / 予防策バンドル / 教育 / 感染予防策 / カテーテル関連血流感染 / 大学病院 / アパッチ2スコア / 大腿静脈 / カテーテル挿入日数 / 集中治療室入室日数 / 中心静脈カテーテル関連血流感染症 / 感染制御チーム / 予防介入策 / 院内感染管理 … More Except Principal Investigator グリコカリックス / 敗血症 / 微小循環 / 内皮細胞機能 / 末梢循環 / ヒドロキシエチルスターチ / 高機能患者シミュレータ / 経鼻高流量酸素療法 / 高機能シミュレーター / 昇圧剤 / 輸液製剤 / アスコルビン酸 / ジェルフォーム / Abdominal Window / 輸液療法 / Abdominal window / Hydroxyethyl starch / Gel Form / Glycocalyx / 換気効果 / 終末期も視野に入れた急性期医療 / 経鼻高流量療法 / 経鼻高流量酸素投与 / 換気 / ROX index / aventilatory mass flow / COVID-19 / 人高機能シミュレータ / 無呼吸酸素化 / 麻酔 / 医学 / 内皮細胞 / アルブミン / 輸液 / HES130 / ヒドロキシルエチルスターチ / 蘇生輸液 / 大量出血 / 呼吸数 / PaO2/FIO2(P/F) / SpO2/FIO2(S/F) / High Flow Nasal Cannula / 死腔の洗い流し / 呼吸負荷軽減作用 / 呼吸仕事量 / 集中治療 / 高流量酸素療法 / 急性呼吸不全 Less

微小循環環境の精察によるグリコカリックスを治療標的にした新規敗血症治療戦略の創出
- Principal Investigator
  
  吉川貴紘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Kyorin University
Elucidation of endothelial cell function by visualization of Gel Form using intravital fluorescence microscopy
- Principal Investigator
  
  鵜澤康二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Kyorin University
Strategy and education for prevention of central venous catheter related blood stream infection in intensive care units.Principal Investigator
- Principal Investigator
  
  萬知子
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Kyorin University
Effects of high flow nasal cannula therapy on apneic oxygenation in a human patient simulator and clinical conditions
- Principal Investigator
  
  Moriyama Kiyoshi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Kyorin University
Strategy and education for prevention of central venous catheter related blood stream infection in intensive care units.Principal Investigator
- Principal Investigator
  
  Yorozu Tomoko
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical and hospital managemen
- Research Institution
  Kyorin University
Elucidation of Pathophysiology by in vivo Imaging of Changes in Endothelial Cell Function in Severe Disease
- Principal Investigator
  
  Uzawa Kohji
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Kyorin University
evaluating the valuable effects of oxygen therapy by high-fidelity human patient simulator
- Principal Investigator
  
  Moriyama Kiyoshi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Kyorin University
Strategy and education for prevention of catheter related bloodstream infections in the intensive care unitPrincipal Investigator
- Principal Investigator
  
  Yorozu Tomoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical and hospital managemen
- Research Institution
  Kyorin University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] The effect of tetrastarch on the endothelial glycocalyx layer in early hemorrhagic shock using fluorescence intravital microscopy: a mouse model2022
- Author(s)
  Ando Tadao、Uzawa Kohji、Yoshikawa Takahiro、Mitsuda Shingo、Akimoto Yoshihiro、Yorozu Tomoko、Ushiyama Akira
- Journal Title
  
  Journal of Anesthesia
  
  Volume: 37 Issue: 1 Pages: 104-118
- DOI
  10.1007/s00540-022-03138-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08929, KAKENHI-PROJECT-22K06816
[Journal Article] Risk factors associated with increased incidences of catheter-related bloodstream infection2022
- Author(s)
  Moriyama Kiyoshi、Ando Tadao、Kotani Mariko、Tokumine Joho、Nakazawa Harumasa、Motoyasu Akira、Yorozu Tomoko
- Journal Title
  
  Medicine
  
  Volume: 101 Issue: 42 Pages: e31160-e31160
- DOI
  10.1097/md.0000000000031160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K10285
[Journal Article] Successful Management of Coronavirus Disease 2019-Related Respiratory Failure Using High-Flow Nasal Cannula Therapy in a Patient with Underlying Pulmonary Artery Hypertension.2022
- Author(s)
  Kotani M, Kohyama T, Moriyama K, Yorozu T
- Journal Title
  
  Case Rep Pulmonol.
  
  Volume: Nov Pages: 1774796-1774796
- DOI
  10.1155/2022/1774796
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08828
[Journal Article] Vascular Endothelial Glycocalyx Plays a Role in the Obesity Paradox According to Intravital Observation2021
- Author(s)
  Mitsuda Shingo、Uzawa Kohji、Sawa Marie、Ando Tadao、Yoshikawa Takahiro、Miyao Hideki、Yorozu Tomoko、Ushiyama Akira
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 8
- DOI
  10.3389/fcvm.2021.727888
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08929
[Journal Article] The protective effect of hydroxyethyl starch solution on the glycocalyx layer in an acute hemorrhage mouse model2020
- Author(s)
  Kohji Uzawa Akira Ushiyama Shingo Mitsuda Tadao Ando Marie Sawa Hideki Miyao Tomoko Yorozu
- Journal Title
  
  Journal of Anesthesia
  
  Volume: 34 Issue: 1 Pages: 36-46
- DOI
  10.1007/s00540-019-02692-8
- NAID
  40022158045
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10973
[Journal Article] High-flow Nasal Cannula Therapy Reduced the Respiratory Rate and Respiratory Distress in a Standard Model Simulator and in Patients With Hypoxemic Respiratory Failure2019
- Author(s)
  Akira Motoyasu, Kiyoshi Moriyama, Hiromu Okano, Tomoko Yorozu
- Journal Title
  
  Ｃｈｒｏｎｉｃｒｅｓｐｉｒａｔｏｒｙｄｉｓｅａｓｅ
  
  Volume: 16 Pages: 1-8
- DOI
  10.1177/1479973119880892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08828
[Journal Article] 経鼻高流量療法の重症肺炎/ 間質性肺炎急性増悪患者に対する使用実態調査2018
- Author(s)
  岡野　弘・金井理一郎・森山　潔・小谷真理子・萬　知子
- Journal Title
  
  人工呼吸
  
  Volume: 35
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10544
[Presentation] 静脈ライン留置期間と中心静脈カテーテル関連血流感染症発生率2023
- Author(s)
  渡辺英伸,渡邊健太,安藤直朗,小谷真理子,森山潔,萬知子
- Organizer
  第50回日本集中治療医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K10285
[Presentation] Transnasal Humidified Rapid-Insufflation Ventilatory Exchange （THRIVE）による無呼吸酸素化の効果-高機能患者シミュレータを用いた研究2020
- Author(s)
  岡野弘、本保晃、森山潔、萬知子
- Organizer
  第67回日本麻酔科学会
- Data Source
  KAKENHI-PROJECT-18K08828
[Presentation] Transnasal Humidified Rapid Insufflation Ventilatory Exchange (THRIVE)による無呼吸酸素化の効果―高機能シミュレータを用いた研究―.2020
- Author(s)
  岡野弘、本保晃、森山潔、萬知子
- Organizer
  日本麻酔学会第67回学術集会
- Data Source
  KAKENHI-PROJECT-18K08828
[Presentation] PREDICTIVE FACTORS OF CATHETER RELATED BLOODSTREAM INFECTION: AN ANALYSIS OF CASE RECORDS OVER FIVE YEARS IN THE INTENSIVE CARE UNIT OF A UNIVERSITY HOSPITAL2019
- Author(s)
  Tomoko Yorozu
- Organizer
  International Anesthesia Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09184
[Presentation] PREDICTIVE FACTORS OF CATHETER RELATED BLOODSTREAM INFECTION: AN ANALYSIS OF CASE RECORDS OVER FIVE YEARS IN THE INTENSIVE CARE UNIT OF A UNIVERSITY HOSPITAL.2019
- Author(s)
  萬　知子
- Organizer
  93rd International Anesthesia Research Society Montreal Canada,93rd International Anesthesia Research Society, Canada
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09184
[Presentation] NEW STRATEGY IS NECESSARY TO REDUCE CATHETER RELATED BLOODSTREAM INFECTION IN THE INTENSIVE CARE UNIT OF A UNIVERSITY HOSPITAL.2017
- Author(s)
  Tomoko Yorozu, Kiyoshi Moriyama, Joho Tokumine, Akira Motoyasu
- Organizer
  91th International Anesthesia Research Society 2017 May 5 Washington DC, USA
- Data Source
  KAKENHI-PROJECT-16K09184
[Presentation] NEW STRATEGY IS NECESSARY TO REDUCE CATHETER RELATED BLOODSTREAM INFECTION IN THE INTENSIVE CARE UNIT OF A UNIVERSITY HOSPITAL2017
- Author(s)
  Tomoko Yorozu, Kiyoshi Moriyama, Akira Motoyasu, Hiromu Okano
- Organizer
  International Anesthesia Research Society 2017 Annual Meeting
- Place of Presentation
  Washington DC, USA
- Year and Date
  2017-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09184
[Presentation] DIFFICULTY OF REDUCING CATHETER RELATED BLOODSTREAM INFECTION IN THE INTENSIVE CARE UNIT OF A UNIVERSITY HOSPITAL DESPITE STRICT IMPLEMENTATION OF A PREVENTIVE MEASURE BUNDLE2016
- Author(s)
  Tomoko Yorozu, Kiyoshi Moriyama, Joho Tokumine, Akirai Motoyasu, Yoshiaki Shiokawa
- Organizer
  90th International Anesthesia Research Society, Annual Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460849
[Presentation] Fluorescence microscopy evaluation of the protective effect of tetrastarch on the glycocalyx layer in an acute hemorrhage mouse model2016
- Author(s)
  鵜澤康二、萬知子、牛山明、宮尾秀樹
- Organizer
  Anesthesiology 2016 Annual Meeting
- Place of Presentation
  シカゴ・アメリカ
- Year and Date
  2016-10-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10973
[Presentation] 杏林大学医学部付属病院集中治療室における中心静脈カテーテル関連血流感染症に関連する因子2015
- Author(s)
  萬知子, 森山潔, 神山智幾, 金井理一郎, 徳嶺譲芳, 森山久美, 山田達也
- Organizer
  日本臨床麻酔学会第35回大会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2015-10-21
- Data Source
  KAKENHI-PROJECT-25460849
[Presentation] FACTORS　ASSOCIATED WITH CATHETER-RELATED BLOODSTREAM INFECTIONS IN THE INTENSIVE CARE UNIT OF A UNIVERSITY HOSPITAL2015
- Author(s)
  Tomoko Yorozu, Kiyoshi Moriyama, Mariko Kotani, Tomoki Kohyama
- Organizer
  International Anesthesia Research Society
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-25460849

1. MORIYAMA Kiyoshi (10296717)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
2. Uzawa Kohji (30530703)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. 牛山明 (60291118)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. 安藤直朗 (10752199)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. 本保晃 (10625578)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 吉川貴紘 (10889166)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. 岡田英志 (30402176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OKANO Hiromu

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Yorozu Tomoko 萬 知子

Research Projects

Research Products

Co-Researchers

微小循環環境の精察によるグリコカリックスを治療標的にした新規敗血症治療戦略の創出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of endothelial cell function by visualization of Gel Form using intravital fluorescence microscopy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Strategy and education for prevention of central venous catheter related blood stream infection in intensive care units.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of high flow nasal cannula therapy on apneic oxygenation in a human patient simulator and clinical conditions

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Strategy and education for prevention of central venous catheter related blood stream infection in intensive care units.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of Pathophysiology by in vivo Imaging of Changes in Endothelial Cell Function in Severe Disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

evaluating the valuable effects of oxygen therapy by high-fidelity human patient simulator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Strategy and education for prevention of catheter related bloodstream infections in the intensive care unitPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The effect of tetrastarch on the endothelial glycocalyx layer in early hemorrhagic shock using fluorescence intravital microscopy: a mouse model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Risk factors associated with increased incidences of catheter-related bloodstream infection2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Successful Management of Coronavirus Disease 2019-Related Respiratory Failure Using High-Flow Nasal Cannula Therapy in a Patient with Underlying Pulmonary Artery Hypertension.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vascular Endothelial Glycocalyx Plays a Role in the Obesity Paradox According to Intravital Observation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The protective effect of hydroxyethyl starch solution on the glycocalyx layer in an acute hemorrhage mouse model2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] High-flow Nasal Cannula Therapy Reduced the Respiratory Rate and Respiratory Distress in a Standard Model Simulator and in Patients With Hypoxemic Respiratory Failure2019

Author(s)

Yorozu Tomoko 萬知子

[Presentation] FACTORS　ASSOCIATED WITH CATHETER-RELATED BLOODSTREAM INFECTIONS IN THE INTENSIVE CARE UNIT OF A UNIVERSITY HOSPITAL2015