ISHIGE Kumiko 石毛久美子

Researcher Number	40212873
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011 – 2019: 日本大学, 薬学部, 教授 2007: Nihon University, College of Pharmacy, Associate Professor 2006: 日本大学, 薬学部, 助教授 2001 – 2002: Nihon University, College of Pharmacy, Full-time lecturer, 薬学部, 講師 2000: 日本大学, 薬学部, 助手 … More 1998 – 1999: 日大, 薬学部, 助手 1996 – 1997: 日本大学, 薬学部, 助手 1993 – 1994: 日本大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Pharmacology in pharmacy / Biological pharmacy Except Principal Investigator 応用薬理学・医療系薬学 / General pharmacology
Keywords	Principal Investigator cyclic AMP responsive element / GR103691 / てんかん欠神発作 / 小胞体ストレス / CBP / lethargicマウス / CREB / Ca^<2+> / 脳梗塞 / 細胞死 … More / 酸化ストレス / HT22細胞 / 薬理学 / 保護薬 / Nrf2 / 脳梗塞モデル / endonlasmic reticulum (ER) stress / oxidative stress / thalamus / lethargic mouse / absence epilepsy / シグナル伝達 / 神経科学 / 脳神経疾患 / mRNA / calmodulin / Neuropeptide Y / MAPキナーゼ / 酸化的ストレス / 視床 / GRP 78 / ER stress / ATF 6 / lethargic mice / GHB model / BDNF / pCREB / 欠神発作 / GRP78 / ATF6 / GHBモデル / neuronal cells / GABA_B receptors / activator protein 1 / gamma-hydoxybutyric acid / 細胞内Ca^<2+> / a ctivator proteinl / activator protein 1 DNA / activator protein1 DNA / 神経細胞初代培養系 / GABA_B受容体 / γ-ヒドロキシ酪酸 / 脳保護薬 / 行動薬理試験 / 低酸素再酸素化細胞死 / ROS / 再灌流障害 / 脳虚血 … More Except Principal Investigator s-allyl-L-cysteine / amyloid β-protein / 4-hydroxynonenal / spinal cord / hippocampus / cultured neurons / neuronal death / s-allylcysteine / アミロイドβタンパク質 / PC12細胞 / caspase / 細胞死 / HNE / 切片培養 / 脊髄 / 海馬 / 培養ニューロン / 神経細胞死 / pentylenetetrazole / ethanol / imidazobenzodiazepines / Ro 15-4513 / benzodiazepine receptors / 小脳顆粒細胞初代培養系 / ラット小脳 / 受容体結合実験 / [^3H]Ro15-4513 / ジアゼパム非感受性 / 抗けいれん作用 / フェノバルビタール / Ro19-4603 / ペンチレンテトラゾール / エタノール / イミダゾベンゾジアデピン / Ro15-4513 / ベンゾジアゼピン受容体 Less

Experimental study in new drugs for stroke and Amyotrophic lateral sclerosisPrincipal Investigator
- Principal Investigator
  
  ISHIGE Kumiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Nihon University
Protective effects of GR-103691-related compound on the stroke mouse modelPrincipal Investigator
- Principal Investigator
  
  ISHIGE Kumiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Nihon University
An exploratory research of new cerebroprotective agentsPrincipal Investigator
- Principal Investigator
  
  ISHIGE Kumiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nihon University
Oxidative and endoplasmic reticulum stress in absence epilepsyPrincipal Investigator
- Principal Investigator
  
  ISHIGE Kumiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nihon University
Studies on signal transduction system in absence seizuresPrincipal Investigator
- Principal Investigator
  
  ISHIGE Kumiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nihon University
Studies on mechanism of neuronal death induced by an amyotrophic lateral sclerosis
- Principal Investigator
  
  ITO Yoshihisa
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Nihon University
てんかん欠神発作における転写調節の制御とMAPキナーゼ系の関与Principal Investigator
- Principal Investigator
  
  石毛久美子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nihon University
Regulation of trascription factor by GABA_B mechanisms in cultured neuronal cellsPrincipal Investigator
- Principal Investigator
  
  ISHIGE Kumiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nihon University
Studies on diazepam-insensitive benzodiazepine receptors
- Principal Investigator
  
  ITO Yoshihisa
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Nihon University

All 2020 2019 2017 2015 2014 2013 2012 2011 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis2020
- Author(s)
  Kosuge Yasuhiro、Kaneko Erina、Nango Hiroshi、Miyagishi Hiroko、Ishige Kumiko、Ito Yoshihisa
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2020 Pages: 1-11
- DOI
  10.1155/2020/1020673
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08317, KAKENHI-PROJECT-17K08965, KAKENHI-PROJECT-17K15759
[Journal Article] Generation of Cellular Reactive Oxygen Species by Activation of the EP2 Receptor Contributes to Prostaglandin E2-Induced Cytotoxicity in Motor Neuron-Like NSC-34 Cells2020
- Author(s)
  Kosuge Yasuhiro、Nango Hiroshi、Kasai Hiroki、Yanagi Takuya、Mawatari Takayuki、Nishiyama Kenta、Miyagishi Hiroko、Ishige Kumiko、Ito Yoshihisa
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2020 Pages: 1-14
- DOI
  10.1155/2020/6101838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08317, KAKENHI-PROJECT-17K08965, KAKENHI-PROJECT-17K15759
[Journal Article] Protective effect of S-allyl-L-cysteine against endoplasmic reticulum stress-induced neuronal death is mediated by inhibition of calpain2014
- Author(s)
  Imai T, Kosuge Y, Endo-Umeda K, Miyagishi H, Ishige K, Makishima M, Ito Y
- Journal Title
  
  Amino Acids
  
  Volume: 46 Pages: 385-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Prostaglandin E<sub>2</sub>-Induced Cell Death is Mediated by Activation of EP2 Receptors in Motor Neuron-like NSC-34 Cells2013
- Author(s)
  Miyagishi H, Kosuge Y, Yoneoka Y, Ozone M, Endo M, Osada N, Ishige K, Kusama-Eguchi K, Ito Y.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 121 Issue: 4 Pages: 347-350
- DOI
  10.1254/jphs.12274SC
- NAID
  10031171146
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Prostaglandin E2-induced cell death is mediated by activation of EP2 receptors in motor neuron-like NSC-34 cells2013
- Author(s)
  Miyagishi H, Ishige K, Kusama-Eguchi K, Ito Y. et al
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 121 Pages: 347-350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Mithramycin, an agent for developing new therapeutic drugs for neurodegenerative diseases2013
- Author(s)
  Osada N, Kosuge Y, Ishige K, Ito Y
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 122 Pages: 251-256
- NAID
  10031196198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Involvement of endoplasmic reticulum stress in neurodegeneration after transient global ischemia-reperfusion2013
- Author(s)
  Ishige K, Osada N, Kosuge Y, Ito Y
- Journal Title
  
  Nihon Yakurigaku Zasshi
  
  Volume: 142 Pages: 9-12
- NAID
  10031185421
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Mithramycin, an agent for developing new therapeutic drugs2013
- Author(s)
  Osada N, Kosuge Y, Ishige K, Ito Y
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 122 Pages: 251-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Expression of microsomal prostaglandin E synthase-1 in the spinal cord in a transgenic mouse model of amyotrophic lateral sclerosis2012
- Author(s)
  Miyagishi H, Kosuge Y, Ishige K, Ito Y
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 118 Pages: 225-236
- NAID
  10030454962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Protective action of mithramycin against neurodegeneration and impairment of synaptic plasticity in the hippocampal CA1 area after transient global ischemia2012
- Author(s)
  Osada N, Kosuge Y, Oguchi S, Miyagishi H, Ishige K, Ito Y
- Journal Title
  
  Neurochem Int
  
  Volume: 60 Pages: 47-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Protective action of mithramycin against neurodegeneration and impairment of synaptic plasticity in the hippocampal CA1 area after transient global ischemia.2012
- Author(s)
  Osada N, Kosuge Y, Oguchi S, Miyagishi H, Ishige K, Ito Y.
- Journal Title
  
  Neurochem. Int
  
  Volume: 60 Pages: 47-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Expression of microsomal prostaglandin E synthase-1 in the spinal cord in a transgenic mouse model of amyotrophic lateral sclerosis.2012
- Author(s)
  Miyagishi H, Kosuge Y, Ishige K, Ito Y.
- Journal Title
  
  J. Pharmacol. Sci.,
  
  Volume: 118 Pages: 225-236
- NAID
  10030454962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation2011
- Author(s)
  Shimba S, Ishige K, et al
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Neuroprotective effect of mithramycin against endoplasmic reticulum stress-induced neurotoxicity in organotypic hippocampal slice cultures2011
- Author(s)
  Kosuge Y, Taniguchi Y, Imai T, Ishige K, Ito Y
- Journal Title
  
  Neuropharmacology
  
  Volume: 61 Pages: 252-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Apelin deficiency accelerates the progression of amyotrophic lateral sclerosis.2011
- Author(s)
  Kasai A, Kinjo T, Ishihara R, Sakai I, Ishimaru Y, Yoshioka Y, Yamamuro A, Ishige K, Ito Y, Maeda S.
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Apelin deficiency accelerates the progression of amyotrophic lateral sclerosis2011
- Author(s)
  Kasai A, Ishige K, et al
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Neuroprotective effect of mithramycin against endoplasmic reticulum stress-induced neurotoxicity in organotypic hippocampal slice cultures.2011
- Author(s)
  Kosuge Y, Taniguchi Y1, Imai T, Ishige K, Ito Y.
- Journal Title
  
  Neuropharmacology
  
  Volume: 61 Pages: 252-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Deficient of a Clock Gene, Brain and Muscle Arnt-Like Protein-1 (BMAL1), Induces Dyslipidemia and Ectopic Fat Formation.2011
- Author(s)
  Shimba S, Ogawa T, Ichihashi Y, Yuki Nakadaira, Kobayashi M, Tezuka M, Kosuge Y, Ishige K, Ito Y. Komiyama K, Okamatsu-Ogura Y, Kimura K, Saito M.
- Journal Title
  
  PLoS ONE
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590117
[Journal Article] Comparative study of hydrogen peroxide-and 4-hydroxy-2-nonenal-induced cell death in HT22 cells2008
- Author(s)
  Ishimura A, Ishige K, Taira T, Shimba S, Ono S, Ariga H, Tezuka M, Ito Y
- Journal Title
  
  Neurochem Int. 52
  
  Pages: 776-785
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590078
[Journal Article] Distinct mechanism of cell death is responsible for tunicamycin-induced ER stress in SK-N-SH and SH-SY5Y cells.2008
- Author(s)
  Oda T, Kosuge Y, Arakawa M, Ishige K, Ito Y.
- Journal Title
  
  Neurosci Res 60
  
  Pages: 29-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590078
[Journal Article] Comparative study of hydrogen peroxide-and 4-hydroxy-2-nonenal-induced cell death in HT22 cells.2008
- Author(s)
  Ishimura A, Ishige K, Taira T, Shimba S, Ono S, Ariga H, Tezuka M, Ito Y
- Journal Title
  
  Neurochem Int 52
  
  Pages: 776-785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590078
[Journal Article] Comparative study of hydrogen peroxide-and 4-hydroxy-2-nonenal induced cell death in HT22 cells.2008
- Author(s)
  Ishimura, A., Ishige, K., Taira, T., Shimba, S., Ono, S., Ariga, H., Tezuka, M., Ito, Y
- Journal Title
  
  Neurochem Int 52
  
  Pages: 776-785
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590078
[Journal Article] Role of caspase-12 in amyloid beta-peptide-induced toxicity in organotypic hippocatnpal slices cultured for long periods2007
- Author(s)
  Ishige K, Takagi N, 他10名
- Journal Title
  
  J Pharmacol Sci. 104
  
  Pages: 46-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590078
[Patent] アポトーシス抑制剤2012
- Inventor(s)
  石毛久美子、伊藤芳久、宮入伸一、齋藤弘明、小菅康弘
- Industrial Property Rights Holder
  石毛久美子、伊藤芳久、宮入伸一、齋藤弘明、小菅康弘
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-278397
- Filing Date
  2012-12-20
- Overseas
- Data Source
  KAKENHI-PROJECT-23590117
[Patent] アポトーシス抑制剤2012
- Inventor(s)
  石毛久美子、伊藤芳久、宮入伸一、齋藤弘明、小菅康弘
- Industrial Property Rights Holder
  石毛久美子、伊藤芳久、宮入伸一、齋藤弘明、小菅康弘
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-278397
- Filing Date
  2012-12-20
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] Methylphenidateの小胞体ストレス誘発細胞死に対する保護効果2020
- Author(s)
  馬場清香、小菅康弘、三浦基文、樫原利佳、南郷拓嗣、宮岸寛子、鳥山正晴、本橋重康、石毛久美子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08317
[Presentation] 宮古ビデンス・ピローサは、筋萎縮性側索硬化症マウスの運動ニューロン死を抑制し、運動機能を改善し、生存期間を延長する2020
- Author(s)
  小菅康弘、南郷拓嗣、設樂尊人、塩原頼太、宮岸寛子、石毛久美子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08317
[Presentation] 注意欠陥・多動性障害（ADHD）治療薬の小胞体ストレス誘発細胞死に対する保護効果2019
- Author(s)
  樫原利佳、小菅康弘、堀越苑子、南郷拓嗣、宮岸寛子、石毛久美子
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17K08317
[Presentation] 成熟ニンニク由来成分S-allyl-L-cysteineは慢性腎臓病モデルマウスにおける海馬のストレス増加を抑制する2019
- Author(s)
  小菅康弘、宮岸寛子、八木沙英子、高橋裕也、下村晃子、南郷拓嗣、石毛久美子、伊藤芳久
- Organizer
  第21回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08317
[Presentation] タイトル MOLECULAR MECHANISM FOR THE NEUROPROTECTIVE EFFECT OF S-ALLYL-L-CYSTEINE AGAINST ENDOPLASMIC RETICULUM STRESS-INDUCED NEURONAL DEATH2019
- Author(s)
  Kosuge Yasuhiro、Imai Toru、Nango Hiroshi、Miyagishi Hiroko、Ito Yoshihisa、Ishige Kumiko
- Organizer
  2019 International Garlic Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08317
[Presentation] 脳梗塞モデルマウスにおけるGR103691誘導体の脳保護作用2017
- Author(s)
  石毛久美子、井口智絵、坪井海頼、片山翔太、齋藤弘明、宮本葵、藤井まき子、小菅康弘、宮入伸一、松本宜明、伊藤芳久
- Organizer
  第39回日本生物学的精神医学会　第47回日本神経精神薬理学会　合同年会
- Data Source
  KAKENHI-PROJECT-17K08317
[Presentation] Assessment of the behavioral disorder in the stroke mouse model by photothrombosis2017
- Author(s)
  石毛久美子、坪井海頼、井口智絵、伊藤芳久
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎・長崎）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460106
[Presentation] GR103691誘導体の脳梗塞モデルマウスにおける障害抑制作用について2017
- Author(s)
  鈴木勇太、井口智絵、飯島千陽、片山翔太、小菅康弘、石毛久美子、伊藤芳久
- Organizer
  第19回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08317
[Presentation] マウスにおけるMPTP投与が協調運動に及ぼす影響2015
- Author(s)
  吉田佳織、藤井雅人、石毛久美子、小菅康弘、伊藤芳久
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（船橋）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-26460106
[Presentation] MPTP 投与マウスにおけるEdaravoneの保護効果2014
- Author(s)
  藤井雅人、石毛久美子、小菅康弘、伊藤芳久
- Organizer
  第130回日本薬理学会関東部会
- Place of Presentation
  東京　星薬科大学
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-26460106
[Presentation] The involvement of endplasmic reticulum stress in neurodegeneration after transient global ischemia-reperfusion2013
- Author(s)
  石毛久美子、他3名
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] GR関連化合物の低酸素再酸素化誘発細胞死抑制効果2013
- Author(s)
  野口真依子、石毛久美子、他5名
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] HT22細胞におけるGR103691およびその関連化合物の低酸素再酸素化油発細胞死抑制効果2013
- Author(s)
  石毛久美子、工藤和真、野口真依子小菅康弘、伊藤芳久
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] HT22細胞におけるGR103691およびその関連化合物の低酸素再酸素化誘発細胞死抑制効果2013
- Author(s)
  石毛久美子、他4名
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本新制精神薬理学会合同大会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] 運動ニューロン様株化細胞NSC-34におけるprostaglandin E2誘発細胞死にはEP2受容体の活性化が関与する2013
- Author(s)
  小菅康弘、石毛久美子、他3名
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] 脳虚血・再灌流後の海馬CA1領域の神経細胞死及び長期増強現象低下に対するMithramycinの保護効果2012
- Author(s)
  長田暢弘、石毛久美子、他3名
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] GR103691の抗酸化物質としての可能性2011
- Author(s)
  石毛久美子、他2名
- Organizer
  第31回日本歯科薬物療法学会
- Place of Presentation
  千葉
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] マウス脳虚血・再灌流モデルにおけるMithramycinの海馬神経細胞保護効果2011
- Author(s)
  長田暢弘、石毛久美子、他4名
- Organizer
  第124回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] 老齢マウスの脳内メラトニンについて2011
- Author(s)
  池口麻衣子、石毛久美子、他2名
- Organizer
  第125回日本薬理学会関東部会
- Place of Presentation
  船橋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] HT22細胞におけるBmal1の誘導に及ぼすホルスコリンおよびアミロイドβタンパク質の影響2011
- Author(s)
  大石汐理、石毛久美子、他2名
- Organizer
  第125回日本薬理学会関東部会
- Place of Presentation
  船橋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] Therapeutic potential of Mithramycin, one of the chemotherapy drug, in brain ischemia2011
- Author(s)
  小菅康弘、石毛久美子、他1名
- Organizer
  The 54th Annual Meeting of Japanese Society for Neurochemistry
- Place of Presentation
  金沢
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] 抗腫瘍性抗生物質Mithramycinの神経保護効果について2011
- Author(s)
  小菅康弘、石毛久美子、他4名
- Organizer
  第31回日本歯科薬物療法学会
- Place of Presentation
  千葉
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] 抗腫瘍性抗生物質Mithramycinの神経保護効果について．2011
- Author(s)
  小菅康弘、谷口耶絵子、宮岸寛子、今井徹、石毛久美子、伊藤芳久
- Organizer
  第31回日本歯科薬物療法学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] 高グルコース刺激がヒト神経芽腫細胞の神経突起の伸展に及ぼす影響2011
- Author(s)
  小菅康弘、石毛久美子、他3名
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  船橋
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-23590117
[Presentation] HT22細胞における低酸素-再酸素化誘発細胞死に対するアポモルヒネの保護効果のメカニズム2008
- Author(s)
  平林美緒子、石毛久美子、小菅康弘、伊藤芳久
- Organizer
  日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-18590078
[Presentation] HT22細胞における4-hydroxy-2-nonenalの細胞死誘発機構2007
- Author(s)
  伊藤芳久、石村淳、石毛久美子、小菅康弘
- Organizer
  第34回日本トキシコロジー学会学術年会
- Place of Presentation
  東京
- Year and Date
  2007-06-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590078
[Presentation] GR103691関連化合物の低酸素再酸素化誘発細胞死抑制効果
- Author(s)
  野口真依子、石毛久美子、小菅康弘、前田佳祐、齋藤弘明、宮入伸一、伊藤芳久
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590117

1. ITO Yoshihisa (50151551)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results

ISHIGE Kumiko 石毛 久美子

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Experimental study in new drugs for stroke and Amyotrophic lateral sclerosisPrincipal Investigator

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Protective effects of GR-103691-related compound on the stroke mouse modelPrincipal Investigator

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An exploratory research of new cerebroprotective agentsPrincipal Investigator

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Oxidative and endoplasmic reticulum stress in absence epilepsyPrincipal Investigator

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Studies on signal transduction system in absence seizuresPrincipal Investigator

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Studies on mechanism of neuronal death induced by an amyotrophic lateral sclerosis

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てんかん欠神発作における転写調節の制御とMAPキナーゼ系の関与Principal Investigator

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Regulation of trascription factor by GABA_B mechanisms in cultured neuronal cellsPrincipal Investigator

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Studies on diazepam-insensitive benzodiazepine receptors

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[Journal Article] Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis2020

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[Journal Article] Generation of Cellular Reactive Oxygen Species by Activation of the EP2 Receptor Contributes to Prostaglandin E2-Induced Cytotoxicity in Motor Neuron-Like NSC-34 Cells2020

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[Journal Article] Protective effect of S-allyl-L-cysteine against endoplasmic reticulum stress-induced neuronal death is mediated by inhibition of calpain2014

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[Journal Article] Prostaglandin E<sub>2</sub>-Induced Cell Death is Mediated by Activation of EP2 Receptors in Motor Neuron-like NSC-34 Cells2013

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ISHIGE Kumiko 石毛久美子