Higashi Sen 東泉

… Alternative Names

東泉ヒガシセン

HIGASHI Sen 東泉

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Researcher Number	40228705
Other IDs
Affiliation (Current)	2025: 九州歯科大学, 歯学部, 助教
Affiliation (based on the past Project Information) *help	2025: 九州歯科大学, 歯学部, 助教 2018 – 2021: 九州歯科大学, 歯学部, 助教 2012: 九州歯科大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Basic Section 57010:Oral biological science-related Except Principal Investigator Eating habits, studies on eating habits
Keywords	Principal Investigator osteocalcin / 糖代謝 / 骨代謝 / 細胞内シグナル / 受容体 / Gpr158 / GPRC6A / 脳 / オステオカルシン / 骨 / 神経細胞 … More Except Principal Investigator … More おくび / 澱粉 / プロアントシアニジン / 胃腔 / 唾液 / 亜硝酸塩 / 澱粉消化 / クロッシン / 一酸化窒素 / ポリフェノール Less

GPR158を標的とする認知機能障害やうつ病の新しい予防および治療戦略の開発Principal Investigator
- Principal Investigator
  
  東泉
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kyushu Dental College
Elucidation of the molecular mechanism of the bone matrix protein osteocalcin in protecting brain functionPrincipal Investigator
- Principal Investigator
  
  Higashi Sen
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu Dental College
Promotion of nitric oxide generation of the stomach, and salivary secretion by a meal.
- Principal Investigator
  
  HIROTA Sachiok
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Kyushu Women's University

All 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Osteocalcin promotes proliferation, differentiation, and survival of PC12?cells2021
- Author(s)
  Ando Eika、Higashi Sen、Mizokami Akiko、Watanabe Seiji、Hirata Masato、Takeuchi Hiroshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 557 Pages: 174-179
- DOI
  10.1016/j.bbrc.2021.03.146
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09510, KAKENHI-PROJECT-17K11649, KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-20H03854
[Journal Article] Effect of aging on bone metabolism: the involvement of complement C1q2021
- Author(s)
  Aonuma Fumiko、Higashi Sen、Tsuka Shintaro、Ohsumi Tomoko、Masaki Chihiro、Hosokawa Ryuji、Takeuchi Hiroshi
- Journal Title
  
  J Prosthodont Res
  
  Volume: 65 Issue: 3 Pages: 393-399
- DOI
  10.2186/jpr.JPOR_2019_644
- NAID
  130008076958
- ISSN
  1883-1958, 1883-9207
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11649, KAKENHI-PROJECT-18K09510
[Journal Article] Substituent effects of cyclic naphthalene diimide on G-quadruplex binding and the inhibition of cancer cell growth.2021
- Author(s)
  Fukuda, H., Sato, S., Zou, T., Higashi, S., Takahashi, O., Habu, M., Sasaguri, M., Tominaga, K., Takenaka, S., Takeuchi, H.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 50 Pages: 128323-128323
- DOI
  10.1016/j.bmcl.2021.128323
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09510, KAKENHI-PROJECT-19H02748, KAKENHI-PROJECT-21H01967, KAKENHI-PROJECT-21K10079, KAKENHI-PROJECT-21K10080
[Journal Article] Modification of TRPV4 activity by acetaminophen.2020
- Author(s)
  Nakagawa, F., Higashi, S., Ando, E., Ohsumi, T., Watanabe, S., Takeuchi, H.
- Journal Title
  
  Heliyon
  
  Volume: 6 Issue: 1 Pages: e03301-e03301
- DOI
  10.1016/j.heliyon.2020.e03301
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11649, KAKENHI-PROJECT-18K09510
[Presentation] 骨基質タンパク質オステオカルシンによる PC12 の形態的・機能的修飾2022
- Author(s)
  2.東泉、安藤瑛香、溝上顕子、渡邉誠之、平田雅人、竹内弘
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] PC12の細胞増殖と神経様分化に対する骨基質タンパク質オステオカルシンの影響2020
- Author(s)
  安藤瑛香，東泉，溝上顕子，渡邉誠之，平田雅人，竹内弘
- Organizer
  第73回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] Effect of bone matrix protein osteocalcin on proliferation and neuronal differentiation of PC12 cells2020
- Author(s)
  安藤瑛香、東泉、溝上顕子、大住伴子、渡邉誠之、平田雅人、竹内弘
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] 骨基質タンパク質オステオカルシンが PC12 細胞に及ぼす影響2020
- Author(s)
  安藤瑛香，東泉，溝上顕子，渡邉誠之，平田雅人，竹内弘
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] 骨基質オステオカルシンによる膵α細胞の性状変化.2019
- Author(s)
  東泉、溝上顕子、大住伴子、平田雅人、竹内弘
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] テロメア構造結合性新規化合物の抗癌効果の検討2019
- Author(s)
  福田晃、東泉、大住伴子、竹内弘
- Organizer
  第61回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] Effect of acetaminophen on TRPV42019
- Author(s)
  中川文雄, 安藤瑛香, 東泉, 大住伴子, 渡邉誠之, 竹内弘
- Organizer
  第66回日本麻酔科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] Anti-cancer effects of newly developed G-quadruplex binders2019
- Author(s)
  Fukuda, H., Sato, S., Higashi, S., Habu, M., Tominaga, K., Takenaka, S., Takeuchi, H.
- Organizer
  12th JKBT
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] 細胞外糖濃度によるマクロファージ極性化の調節.2018
- Author(s)
  工藤崇裕、臼井通彦、東泉、大住伴子、中島啓介、竹内弘
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] Effect of extracellular glucose concentration on macrophage polarization.2018
- Author(s)
  Kudo, T., Usui, M., Higashi, S., Ohsumi, T., Nakashima, K., Takeuchi, H.
- Organizer
  Asia-pacific Conference in Fukuoka 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] 培地グルコース濃度はAMPKを介してマクロファージ極性化に影響する.2018
- Author(s)
  工藤崇裕、臼井通彦、東泉、大住伴子、竹内弘
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09510
[Presentation] 培地グルコース濃度がマクロファージの性質に与える影響について.2018
- Author(s)
  工藤崇裕、臼井通彦、東泉、大住伴子、中島啓介、竹内弘
- Organizer
  第78回九州歯科学会
- Data Source
  KAKENHI-PROJECT-18K09510

1. HIROTA Sachiok (00312140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. NISHIDA Makiko (00268814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TAKAHAMA Umeo (30106273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 竹内弘 (70304813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results

Higashi Sen 東 泉

東 泉 ヒガシ セン

HIGASHI Sen 東 泉

Research Projects

Research Products

Co-Researchers

GPR158を標的とする認知機能障害やうつ病の新しい予防および治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism of the bone matrix protein osteocalcin in protecting brain functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Promotion of nitric oxide generation of the stomach, and salivary secretion by a meal.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Osteocalcin promotes proliferation, differentiation, and survival of PC12?cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of aging on bone metabolism: the involvement of complement C1q2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Substituent effects of cyclic naphthalene diimide on G-quadruplex binding and the inhibition of cancer cell growth.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modification of TRPV4 activity by acetaminophen.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 骨基質タンパク質オステオカルシンによる PC12 の形態的・機能的修飾2022

Author(s)

Organizer

Data Source

[Presentation] PC12の細胞増殖と神経様分化に対する骨基質タンパク質オステオカルシンの影響2020

Author(s)

Organizer

Data Source

[Presentation] Effect of bone matrix protein osteocalcin on proliferation and neuronal differentiation of PC12 cells2020

Author(s)

Organizer

Data Source

[Presentation] 骨基質タンパク質オステオカルシンが PC12 細胞に及ぼす影響2020

Author(s)

Organizer

Data Source

[Presentation] 骨基質オステオカルシンによる膵α細胞の性状変化.2019

Author(s)

Organizer

Data Source

[Presentation] テロメア構造結合性新規化合物の抗癌効果の検討2019

Author(s)

Organizer

Data Source

[Presentation] Effect of acetaminophen on TRPV42019

Author(s)

Organizer

Data Source

[Presentation] Anti-cancer effects of newly developed G-quadruplex binders2019

Author(s)

Organizer

Data Source

[Presentation] 細胞外糖濃度によるマクロファージ極性化の調節.2018

Higashi Sen 東泉

東泉ヒガシセン

HIGASHI Sen 東泉