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Kakinuma Yoshihiko  柿沼 由彦

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KAKINUMA Yoshihiko  柿沼 由彦

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Researcher Number 40233944
Other IDs
Affiliation (Current) 2025: 日本医科大学, 大学院医学研究科, 大学院教授
Affiliation (based on the past Project Information) *help 2016 – 2025: 日本医科大学, 大学院医学研究科, 大学院教授
2017: 日本医科大学, 大学院医学研究科, 教授
2013 – 2015: 日本医科大学, 医学(系)研究科(研究院), 教授
2013: 日本医科大学, 大学院・医学研究科, 大学院教授
2013: 日本医科大学, 大学院医学研究科, 大学院教授 … More
2013: 高知大学, 教育研究部医療学系, 准教授
2011: 高知大学, 医療学系, 准教授
2009 – 2011: Kochi University, 教育研究部・医療学系, 准教授
2008: Kochi University, 教育研究部医療学系, 准教授 Less
Review Section/Research Field
Principal Investigator
General pharmacology / Basic Section 59040:Nutrition science and health science-related
Except Principal Investigator
Medical systems / Basic Section 59040:Nutrition science and health science-related / Basic Section 49030:Experimental pathology-related / Basic Section 59020:Sports sciences-related / Neurochemistry/Neuropharmacology / Experimental pathology / Urology / Laboratory medicine
Keywords
Principal Investigator
アセチルコリン / エネルギー代謝 / 心臓 / 非神経性コリン作働系 / 非神経性心臓コリン作動系 / 心筋細胞 / コリン作動系 / 鰹節抽出物 / 血液脳関門 / 鰹節熱抽出物 … More / 抗炎症 / 抗痙攣作用 / 抗ストレス作用 / 抗不安作用 / 抗うつ作用 / acetylcholine (ACh) / 非神経性コリン作動系(NNCCS) / 抗うつ・抗ストレス / 非中枢性非神経性アセチルコリン産生系 / 中枢神経 / 抗うつ効果 / 迷走神経 / ACh / 中枢神経系 / 心筋 / 心室筋 / 心機能 / 遺伝子改変マウス / ミトコンドリア / 酸素消費量 / 血液 / 心血管 / VEGF / 下肢虚血モデル / 血管新生 / 循環 … More
Except Principal Investigator
副交感神経系 / snoRNA / 核小体低分子RNA / 心筋 / 老化 / 肝臓 / 糖代謝 / 迷走神経 / 副交感神経 / 虚血再灌流モデル / ストレス / 神経インターフェース / トランスレーショナルリサーチ / 循環器・高血圧 / 非分裂性細胞 / exercise hyperemia / 運動トレーニング / コリンアセチルトランスフェラーゼ / 非神経性コリン作動系 / 血管内皮細胞 / 虚血再検流刺激 / 脂肪肝炎 / 糖尿病 / 変性タンパク質 / マーカー / 老化マーカー / 老化マウス / RNAシーケンス / マウス / 心筋細胞 / 分裂停止細胞 / ミトコンドリア / トランスクリプトーム解析 / 分裂終了細胞 / 非心筋 / エネルギ産生 / 解糖系 / クエン酸回路 / エネルギー産生 / 鬱病 / 視床下部 / 酸化ストレス / 交感神経系 / 腹側被蓋野 / 青斑核 / 黒質 / ノルアドレナリン / ドーパミン / ミクログリア / パーキンソン病 / 慢性ストレス / 臓器保護性 / 血糖低下 / 末梢虚血再刊流刺激 / 糖新生 / 糖取り込み / VHLノックアウトマウス / HIF2a / HIF1a / von Hippel-Lindau病 / 腎細胞癌 / 腎癌 / VHL遺伝子 / ES細胞 / HIF2α / HIF1α / VHL遺伝子変異 / 中枢性エネルギー枯渇 / アドレナリン / 慢性炎症 / 性差 / 高齢 / 低侵襲治療システム / 起立性低血圧 / 医療工学 / 医療・福祉 / 先端機能デバイス / 神経インターフェース / トランスレーショナルリサーチ / 臓器保存・治療システム / トレンスレーショナルリサーチ Less
  • Research Projects

    (18 results)
  • Research Products

    (201 results)
  • Co-Researchers

    (37 People)
  •  非神経性コリン作動系活性化制御物質の可能性とその生理機能の解析Principal Investigator

    • Principal Investigator
      柿沼 由彦
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Nippon Medical School
  •  糖尿病合併NASHに対する末梢虚血再灌流刺激の治療有用性―その機序の基礎的解明―

    • Principal Investigator
      倉林 睦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kochi University
  •  内皮由来アセチルコリンは糖尿病における筋収縮依存性血管応答の低下に関与するか?

    • Principal Investigator
      曽野部 崇
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Nippon Medical School
  •  老齢マウス心筋細胞における核小体低分子RNA(snoRNA)の機能解析

    • Principal Investigator
      竹中 康浩
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Nippon Medical School
  •  Transcriptomic analyses of mouse cardiac myocytes and cardiac non-myocyte cells: postmitotic vs. proliferative cells

    • Principal Investigator
      Takenaka Yasuhiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Nippon Medical School
  •  コリン作動系修飾物を介した血液脳関門強化と抗炎症作用による認知機能介入の可能性Principal Investigator

    • Principal Investigator
      柿沼 由彦
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Nippon Medical School
  •  Murine remote ischemic preconditioning suppresses diabetic ketoacidosis by enhancing glycolysis and entry into tricarboxylic acid cycle in the liver with upregulation of hepatic glucose transporter-4

    • Principal Investigator
      Kurabayashi Atsushi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kochi University
  •  The effects of the augmented non-neuronal cardiac cholinergic system on the central nervous systemPrincipal Investigator

    • Principal Investigator
      Kakinuma Yoshihiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Nippon Medical School
  •  Murine remote preconditioning increases glucose uptake and suppresses gluconeogenesis in hepatocytes via a brain-liver neurocircuit, leading to counteracting glucose intolerance

    • Principal Investigator
      Kurabayashi Atsushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kochi University
  •  Investigation of microglia and chronic stress in the onset of Parkinson disease

    • Principal Investigator
      Sugama Shuei
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Nippon Medical School
  •  The study investigating the effects of non-neuronal cardiac cholinergic system on intervention of the metabolic remodellingPrincipal Investigator

    • Principal Investigator
      Kakinuma Yoshihiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Nippon Medical School
  •  A new therapeutic strategy against chronic heart failure: chronic vagal nerve stimulation

    • Principal Investigator
      SATO Takayuki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical systems
    • Research Institution
      Kochi University
  •  Development of an artificial feedback system with abdominal electrical stimulation for treatment of orthostatic hypotension

    • Principal Investigator
      YAMASAKI FUMIYASU
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical systems
    • Research Institution
      Kochi University
  •  たこつぼ心筋症の成因に関する研究-糖代謝・炎症を機軸とした中枢神経系の関与

    • Principal Investigator
      公文 義雄
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kochi University
  •  Analyses of altered VHL protein function in the clear cell renal carcinoma(CRCC) and its utilization for CRCC patients.

    • Principal Investigator
      SHUIN TARO
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kochi University
  •  Involvement of a non-neuronal cardiac cholinergic system in energy metabolism and pathophysiological situationsPrincipal Investigator

    • Principal Investigator
      KAKINUMA Yoshihiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kochi University
  •  Neural Interface Therapy for Severe Heart Failure

    • Principal Investigator
      SATO Takayuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical systems
    • Research Institution
      Kochi University
  •  How angiogenesis is regulated by pharmacological intervention of the intracellular cholinergic system?Principal Investigator

    • Principal Investigator
      KAKINUMA Yoshihiko, 柿沼 由彦
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kochi University

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] 心臓の力2016

    • Author(s)
      柿沼由彦
    • Total Pages
      221
    • Publisher
      講談社(ブルーバックス)
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Book] 心臓の力-休めない臓器はなぜ「それ」を宿したのか2015

    • Author(s)
      柿沼 由彦
    • Total Pages
      221
    • Publisher
      講談社(ブルーバックス)
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] Transcriptome Analysis Reveals Enhancement of Cardiogenesis-Related Signaling Pathways by S-nitroso-N-pivaloyl-D-penicillamine (SNPiP): Implications for Improved Diastolic Function and Cardiac Performance2024

    • Author(s)
      Takenaka Yasuhiro、Hirasaki Masataka、Bono Hidemasa、Nakamura Shigeo、Kakinuma Yoshihiko
    • Journal Title

      Journal of Cardiovascular Pharmacology

      Volume: 1 Issue: 5 Pages: 433-445

    • DOI

      10.1097/fjc.0000000000001552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Journal Article] Temporal inhibition of the electron transport chain attenuates stress-induced cellular senescence by prolonged disturbance of proteostasis in human fibroblasts2023

    • Author(s)
      Yasuhiro Takenaka, Ikuo Inoue, Masataka Hirasaki, Masaaki Ikeda, Yoshihiko Kakinuma
    • Journal Title

      FEBS Journal

      Volume: in press Issue: 15 Pages: 3843-3857

    • DOI

      10.1111/febs.16785

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Journal Article] Positive feedback regulation of Pparγ1sv and Pparγ2 during adipogenesis in 3T3-L1 cells2023

    • Author(s)
      Takenaka Yasuhiro、Kakinuma Yoshihiko、Inoue Ikuo
    • Journal Title

      bioRxiv

      Volume: 1

    • DOI

      10.1101/2023.08.03.551916

    • Open Access
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Journal Article] Transcriptome analyses of mouse cardiac myocytes and non-cardiomyocytes: postmitotic vs. proliferative cells2023

    • Author(s)
      Takenaka Yasuhiro、Hirasaki Masataka、Inoue Ikuo、Ikeda Masaaki、Ohata Hisayuki、Kakinuma Yoshihiko
    • Journal Title

      bioRxiv

      Volume: 1

    • DOI

      10.1101/2023.08.20.554007

    • Open Access
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Journal Article] Prolonged disturbance of proteostasis induces cellular senescence via temporal mitochondrial dysfunction and subsequent mitochondrial accumulation in human fibroblasts2022

    • Author(s)
      Yasuhiro Takenaka, Ikuo Inoue, Takanari Nakano, Masaaki Ikeda, Yoshihiko Kakinuma
    • Journal Title

      FEBS Journal

      Volume: 289(6) Issue: 6 Pages: 1650-1667

    • DOI

      10.1111/febs.16249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Journal Article] Murine remote ischemic preconditioning upregulates preferentially hepatic glucose transporter-4 via its plasma membrane translocation, leading to accumulating glycogen in the liver.2022

    • Author(s)
      Kurabayashi A, Furihata K, Iwashita W, Tanaka C, Fukuhara H, Inoue K, Furihata M, Kakinuma Y
    • Journal Title

      Life sciences.

      Volume: 290 Pages: 120261-120261

    • DOI

      10.1016/j.lfs.2021.120261

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07461, KAKENHI-PROJECT-19K07483
  • [Journal Article] The physiological effects of the non-neuronal cardiac cholinergic system on the heart and extra-cardiac organs2022

    • Author(s)
      柿沼 由彦
    • Journal Title

      Hikaku seiri seikagaku(Comparative Physiology and Biochemistry)

      Volume: 39 Issue: 3 Pages: 132-139

    • DOI

      10.3330/hikakuseiriseika.39.132

    • ISSN
      0916-3786, 1881-9346
    • Year and Date
      2022-12-07
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K11658
  • [Journal Article] Katsuo extract derived from dried bonito plays a role in systemic anti-inflammation and consolidation of the blood-brain barrier to regulate higher brain functions2022

    • Author(s)
      Hokari Y, Sekine A, Kai Y, Oikawa S, Mano A, Ohata H, Sugama S, Kakinuma Y
    • Journal Title

      Frontiers in Natural Products

      Volume: 1 Pages: 1-13

    • DOI

      10.3389/fntpr.2022.969433

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K11658
  • [Journal Article] Murine remote preconditioning increases glucose uptake and suppresses gluconeogenesis in hepatocytes via a brain-liver neurocircuit, leading to counteracting glucose intolerance2018

    • Author(s)
      Kurabayashi Atsushi、Tanaka Chiharu、Matsumoto Waka、Naganuma Seiji、Furihata Mutsuo、Inoue Keiji、Kakinuma Yoshihiko
    • Journal Title

      Diabetes Research and Clinical Practice

      Volume: 139 Pages: 288-299

    • DOI

      10.1016/j.diabres.2018.03.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08427, KAKENHI-PROJECT-16K08560
  • [Journal Article] Evaluation of Teneligliptin Effects on Transcriptional Activity of PPARγ in Cell-Based Assays2018

    • Author(s)
      Takenaka Yasuhiro、Inoue Ikuo、Nakano Takanari、Ikeda Masaaki、Kakinuma Yoshihiko、Ikegami Yuichi、Shimada Akira、Noda Mitsuhiko
    • Journal Title

      Journal of Nippon Medical School

      Volume: 85 Issue: 2 Pages: 95-101

    • DOI

      10.1272/jnms.2018_85-15

    • NAID

      130006731178

    • ISSN
      1345-4676, 1347-3409
    • Year and Date
      2018-04-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08560, KAKENHI-PROJECT-16K15193
  • [Journal Article] Involvement of Noncoding RNAs in Stress-Related Neuropsychiatric Diseases Caused by DOHaD Theory2018

    • Author(s)
      Nemoto Takahiro、Kakinuma Yoshihiko
    • Journal Title

      Adv Exp Med Biol

      Volume: 1012 Pages: 49-59

    • DOI

      10.1007/978-981-10-5526-3_6

    • ISBN
      9789811055256, 9789811055263
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10195, KAKENHI-PROJECT-16K08560
  • [Journal Article] The non-neuronal cholinergic system in the heart: A comprehensive review2018

    • Author(s)
      Saw Eng Leng、Kakinuma Yoshihiko、Fronius Martin、Katare Rajesh
    • Journal Title

      Journal of Molecular and Cellular Cardiology

      Volume: 125 Pages: 129-139

    • DOI

      10.1016/j.yjmcc.2018.10.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Journal Article] Corrigendum to "Chronic restraint stress triggers dopaminergic and noradrenergic neurodegeneration: Possible role of chronic stress in the onset of Parkinson's disease" [Brain Behav. Immun. 51 (2016) 39-46].2017

    • Author(s)
      Sugama S, Sekiyama K, Kodama T, Takamatsu Y, Takenouchi T, Hashimoto M, Conti B, Kakinuma Y.
    • Journal Title

      Brain Behav Immun.

      Volume: 61 Pages: 389-389

    • DOI

      10.1016/j.bbi.2016.12.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Journal Article] Various Regulatory Modes for Circadian Rhythmicity and Sexual Dimorphism in the Non-Neuronal Cardiac Cholinergic System.2017

    • Author(s)
      Oikawa S, Kai Y, Mano A, Ohata H, Nemoto T, Kakinuma Y.
    • Journal Title

      J Cardiovasc Transl Res

      Volume: 10 Issue: 4 Pages: 411-422

    • DOI

      10.1007/s12265-017-9750-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Journal Article] Lack of interleukin-13 receptor a1 delays the loss of dopaminergic neurons during chronic stress2017

    • Author(s)
      Mori S, Sugama S, Nguyen W, Michel T, Sanna MG, Sanchez-Alavez M, Cintron-Colon R, Moroncini G, Kakinuma Y, Maher P, Conti B
    • Journal Title

      J Neuroinflammation

      Volume: 14 Pages: 88-88

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06783
  • [Journal Article] Erratum to: Various Regulatory Modes for Circadian Rhythmicity and Sexual Dimorphism in the Non-Neuronal Cardiac Cholinergic System.2017

    • Author(s)
      Oikawa S, Kai Y, Mano A, Ohata H, Nemoto T, Kakinuma Y.
    • Journal Title

      J Cardiovasc Transl Res.

      Volume: 10 Issue: 4 Pages: 435-435

    • DOI

      10.1007/s12265-017-9760-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Journal Article] Novel channel-mediated choline transport in cholinergic neurons of the mouse retina.2017

    • Author(s)
      Ishii T, Homma K, Mano A, Akagi T, Shigematsu Y, Shimoda Y, Inoue H, Kakinuma Y, Kaneda M.
    • Journal Title

      J Neurophysiol.

      Volume: 118 Issue: 4 Pages: 1952-1961

    • DOI

      10.1152/jn.00506.2016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08560, KAKENHI-PROJECT-16K11305, KAKENHI-PROJECT-17K16990
  • [Journal Article] Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress.2017

    • Author(s)
      Mori S, Sugama S, Nguyen W, Michel T, Sanna MG, Sanchez-Alavez M, Cintron-Colon R, Moroncini G, Kakinuma Y, Maher P, Conti B.
    • Journal Title

      J Neuroinflammation

      Volume: 14 Issue: 1 Pages: 88-88

    • DOI

      10.1186/s12974-017-0862-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Journal Article] Letter to the Editor Re:"Reconsidering the role of glial cells in chronic stress-induced dopaminergic neurons loss within the substantia nigra? Friend of foe?" by Ong et al. Brain Behavior and Immunity, 2016.2017

    • Author(s)
      Sugama S, Kakinuma Y
    • Journal Title

      Brain Behav Immun

      Volume: 60 Pages: 383-383

    • DOI

      10.1016/j.bbi.2016.11.028

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K06783, KAKENHI-PROJECT-16K08560
  • [Journal Article] Loss of dopaminergic neurons occurs in the ventral tegmental area and hypothalamus of rats following chronic stress: Possible pathogenetic loci for depression involved in Parkinson's disease2016

    • Author(s)
      Sugama S, Kakinuma Y
    • Journal Title

      Neurosci Res

      Volume: 111 Pages: 48-55

    • DOI

      10.1016/j.neures.2016.04.008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K06783, KAKENHI-PROJECT-16K08560
  • [Journal Article] Distribution of Corticotrophin-Releasing Factor Type 1 Receptor-Like Immunoreactivity in the Rat Pituitary.2016

    • Author(s)
      Mano-Otagiri A, Nemoto T, Yamauchi N, Kakinuma Y, Shibasaki T.
    • Journal Title

      Journal of Neuroendocrinology

      Volume: 28 Issue: 12

    • DOI

      10.1111/jne.12440

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Journal Article] Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.2016

    • Author(s)
      Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T.
    • Journal Title

      Eur J Pharmacol.

      Volume: 789 Pages: 17-26

    • DOI

      10.1016/j.ejphar.2016.06.053

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461059, KAKENHI-PROJECT-16K08560, KAKENHI-PROJECT-16K09441, KAKENHI-PROJECT-16K19410
  • [Journal Article] Non-neuronal cardiac cholinergic system influences CNS via the vagus nerve to acquire a stress-refractory propensity.2016

    • Author(s)
      Oikawa S, Kai Y, Tsuda M, Ohata H, Mano A, Mizoguchi N, Sugama S, Nemoto T, Suzuki K, Kurabayashi A, Muramoto K, Kaneda M, and Kakinuma Y.
    • Journal Title

      Clinical Science

      Volume: 130(21) Issue: 21 Pages: 1913-1928

    • DOI

      10.1042/cs20160277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26463192, KAKENHI-PROJECT-15K06783, KAKENHI-PROJECT-16K08560, KAKENHI-PROJECT-15K15043
  • [Journal Article] Chronic restraint stress triggers dopaminergic and noradrenergic neurodegeneration: Possible role of chronic stress in the onset of Parkinson's disease2016

    • Author(s)
      Sugama S, Sekiyama K, Kodama T, Takamatsu Y, Takenouchi T, Hashimoto M, Conti B, Kakinuma Y
    • Journal Title

      Brain Behav Immun

      Volume: 51 Pages: 39-46

    • DOI

      10.1016/j.bbi.2015.08.015

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06783, KAKENHI-PROJECT-26640033, KAKENHI-PROJECT-25460333, KAKENHI-PROJECT-25290019, KAKENHI-PROJECT-16K08560
  • [Journal Article] Restraint-induced glucocorticoid receptor downregulation is dysregulated in high fat diet-fed rats likely from impairment of miR-142-3p expression in the hypothalamus and hippocampus.2015

    • Author(s)
      Nemoto T, Kakinuma Y, Shibasaki T.
    • Journal Title

      Am J Life Sciences

      Volume: 3 Issue: 3 Pages: 24-30

    • DOI

      10.11648/j.ajls.s.2015030302.15

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] Remote ischemic preconditioning with a specialized protocol activates the non-neuronal cardiac cholinergic system and increases ATP content in the heart.2015

    • Author(s)
      Oikawa S, Mano A, Takahashi R, Kakinuma Y.
    • Journal Title

      Int Immunopharmacol.

      Volume: 29 Issue: 1 Pages: 181-184

    • DOI

      10.1016/j.intimp.2015.06.004

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] Impaired miR449a-induced downregulation of Crhr1 expression in low-birth-weight rats.2015

    • Author(s)
      Nemoto T, Kakinuma Y, Shibasaki T.
    • Journal Title

      J Endocrinol

      Volume: 224 Issue: 2 Pages: 195-203

    • DOI

      10.1530/joe-14-0537

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] Nicotinic receptor-dependent and -independent effects of galantamine, an acetylcholinesterase inhibitor, on the non-neuronal acetylcholine system in C2C12 cells.2015

    • Author(s)
      Oikawa S, Mano A, Iketani M, Kakinuma Y
    • Journal Title

      Int Immunopharmacol

      Volume: 29 Issue: 1 Pages: 31-35

    • DOI

      10.1016/j.intimp.2015.04.057

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] Future perspectives of a cardiac non-neuronal acetylcholine system targeting cardiovascular diseases as an adjunctive tool for metabolic intervention.2015

    • Author(s)
      Kakinuma Y.
    • Journal Title

      Int Immunopharmacol

      Volume: 29 Issue: 1 Pages: 185-188

    • DOI

      10.1016/j.intimp.2015.05.029

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] Donepezil Can Improve Ischemic Muscle Atrophy by Activating Angiomyogenic Properties of Satellite Cells2014

    • Author(s)
      Noguchi T, Kakinuma Y, Arikawa M, Okazaki K, Hoshino E, Iiyama T, Kubo T, Kitaoka H, Doi Y, Sato T
    • Journal Title

      Circ J

      Volume: 78 Issue: 9 Pages: 2317-2324

    • DOI

      10.1253/circj.CJ-14-0095

    • NAID

      130004677615

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460333, KAKENHI-PROJECT-25461059, KAKENHI-PROJECT-26670080
  • [Journal Article] Donepezil, Therapeutic Acetylcholinesterase Inhibitor, Prevents the Progression of Ventricular Dysfunction by Promoting Myocardial Glucose Utilization in Rat Model of Chronic Heart Failure Following Myocardial Infarction2014

    • Author(s)
      Mikihiko Arikawa, Yoshihiko Kakinuma, Tatsuya Noguchi, Takayuki Sato
    • Journal Title

      Cardiol Pharmacol

      Volume: 3 Issue: 02 Pages: 1000121-1000121

    • DOI

      10.4172/2329-6607.1000121

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460333, KAKENHI-PROJECT-25461059, KAKENHI-PROJECT-26670080
  • [Journal Article] A Concept of a Nonneuronal Cardiac Cholinergic System2014

    • Author(s)
      Kakinuma Y
    • Journal Title

      Journal of Nippon Medical School

      Volume: 81 Issue: 5 Pages: 296-297

    • DOI

      10.1272/jnms.81.296

    • NAID

      130004703880

    • ISSN
      1345-4676, 1347-3409
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] Nicotinic and non-nicotinic receptor-mediated mechanisms responsible for anti-atrophy effects in muscle2014

    • Author(s)
      Yoshihiko Kakinuma
    • Journal Title

      Receptors & Clinical Investigation

      Volume: 1

    • DOI

      10.14800/rci.286

    • Open Access
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] A non-neuronal cholinergic system regulates cellular ATP levels to maintain cell viability2014

    • Author(s)
      Oikawa S, Iketani M, Kakinuma Y
    • Journal Title

      Cell Physiol Biochem

      Volume: 34 Issue: 3 Pages: 781-789

    • DOI

      10.1159/000363042

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] Anti-muscle atrophy effect of nicotine targets muscle satellite cells partly through an alpha7 nicotinic receptor in a murine hindlimb ischemia model2014

    • Author(s)
      Kakinuma Y, Tatsuya Noguchi T, Okazaki K, Oikawa S, Iketani M, Kurabayashi M, Furihata M, Sato T
    • Journal Title

      Translational Research

      Volume: 164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Journal Article] Antimuscle atrophy effect of nicotine targets muscle satellite cells partly through an α7 nicotinic receptor in a murine hindlimb ischemia model.2014

    • Author(s)
      Kakinuma Y, Noguchi T, Okazaki K, Oikawa S, Iketani M, Kurabayashi M, Furihata M, Sato T
    • Journal Title

      Translational Research

      Volume: 164 Issue: 1 Pages: 32-45

    • DOI

      10.1016/j.trsl.2014.02.005

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590412, KAKENHI-PROJECT-25460333, KAKENHI-PROJECT-26670080
  • [Journal Article] Heart-specific overexpression of ch oline acetyltransferase gene protect s murine heart against ischemia thro ugh hypoxia-inducible factor-1α-rel ated defense mechanisms2013

    • Author(s)
      Kakinuma Y, Tsuda M, Okazaki K, Akiy ama T, Arikawa M, Noguchi T, Sato T
    • Journal Title

      J Am Heart Assoc

      Volume: 2 Issue: 1

    • DOI

      10.1161/jaha.112.004887

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300191, KAKENHI-PROJECT-23592691, KAKENHI-PROJECT-23790858
  • [Journal Article] Condit ional VHL gene deletion causes hypog lycemic death associated with dispro portionately increased glucose uptak e by hepatocytes through an upregula ted IGF-I receptor2013

    • Author(s)
      Kurabayashi A, Kakinuma Y, Morita T, Inoue K, Sato T, Furihata M
    • Journal Title

      PLoS One

      Volume: 8 Issue: 7 Pages: e69139-e69139

    • DOI

      10.1371/journal.pone.0069139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Journal Article] A non-ne uronal cardiac cholinergic system pl ays a protective role in myocardium salvage during ischemic insults2012

    • Author(s)
      Kakinuma Y, Akiyama T, Okazaki K, Ar ikawa M, Noguchi T, Sato T
    • Journal Title

      PLoS ONE

      Volume: 7 Issue: 11 Pages: e50761-e50761

    • DOI

      10.1371/journal.pone.0050761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300191, KAKENHI-PROJECT-23592691, KAKENHI-PROJECT-23790858
  • [Journal Article] Influences of donepezil on card iovascular system--possible therapeu tic benefits for heart failure--done pezil cardiac test registry (DOCTER) study2012

    • Author(s)
      Kubo T, Sato T, Noguchi T, Kitaoka H, Yamasaki F, Kamimura N, Shimodera S, Iiyama T, Kumagai N, Kakinuma Y, Di edrich A, Jordan J, Robertson D, Doi YL
    • Journal Title

      J Cardiovasc Pharmacol

      Volume: 60 Issue: 3 Pages: 310-314

    • DOI

      10.1097/fjc.0b013e3182609a74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300191, KAKENHI-PROJECT-23591741
  • [Journal Article] Robertson D, Doi YL. Influences of donepezil on cardiovascular system--possible therapeutic benefits for heart fail ure--donepezil cardiac test registr y (DOCTER) study2012

    • Author(s)
      Kubo T, Sato T, Noguchi T, Kitaoka H, Yamasaki F, Kamimura N, Shimoder a S, Iiyama T, Kumagai N, Kakinuma Y, Diedrich A, Jordan J
    • Journal Title

      J Cardiovasc Pha rmacol

      Volume: 60(3) Pages: 310-4

    • URL

      http://journals.lww.com/cardiovascularpharm/pages/results.aspx?txtKeywords=yamasaki%20f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500560
  • [Journal Article] Systemic inflammation impairs cardiac glucose uptake2012

    • Author(s)
      Kakinuma Y, Okada S, Nogami M, Sano S, Kumon Y.
    • Journal Title

      Int J Cardiol

      Volume: 154 Pages: 203-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Systemic inflammation impairs cardiac glucose uptake.2012

    • Author(s)
      Kakinuma Y, Okada S, Nogami M, Sano S, Kumon Y.
    • Journal Title

      Int J Cardiol.

      Volume: 154(2) Pages: 203-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590678
  • [Journal Article] アセチルコリンのpleiotropic actionから心筋内アセチルコリン産生系まで2011

    • Author(s)
      柿沼由彦
    • Journal Title

      自律神経

      Volume: 48 Pages: 173-175

    • NAID

      10029549389

    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Donepezil, anti-Alzheimer's disease drug, prevents cardiac rupture during acute phase of myocardial infarction in mice2011

    • Author(s)
      Arikawa M, Kakinuma Y, et al
    • Journal Title

      PLoS One

      Volume: 6 Issue: 7 Pages: e20629-e20629

    • DOI

      10.1371/journal.pone.0020629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283, KAKENHI-PROJECT-23300191, KAKENHI-PROJECT-23500560, KAKENHI-PROJECT-23790858
  • [Journal Article] Conditional VHL gene deletion activates a local NO-VEGF axis in a balanced manner reinforcing resistance to endothelium-targeted glomerulonephropathy2011

    • Author(s)
      Morita T, Kakinuma Y, et al
    • Journal Title

      Nephrol Dial Transplant

      Volume: 26 Issue: 12 Pages: 4023-4031

    • DOI

      10.1093/ndt/gfr176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283, KAKENHI-PROJECT-22591182, KAKENHI-PROJECT-23300191, KAKENHI-PROJECT-23591573
  • [Journal Article] Conditional VHL gene deletion activates a local NO-VEGF axis in a balanced manner reinforcing resistance to endothelium-targeted glomerulonephropathy2011

    • Author(s)
      Morita T, Kakinuma Y, Kurabayashi A, Fujieda M, Sato T, Shuin T, Furihata M, Wakiguchi H
    • Journal Title

      Nephrol Dial Transpl

      Volume: 26 Pages: 4023-4031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Donepezil, Anti-Alzheimer' s Disease Drug, Prevents Cardiac Rupture during Acute Phase of Myocardial Infarction in Mice2011

    • Author(s)
      Arikawa M, Kakinuma Y, Handa T, Yamasaki F, Sato T
    • Journal Title

      PLoS One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Donepezil, an acetylcholinesterase inhibitor against Alzheimer' s dementia, promotes angiogenesis in an ischemic hindlimb model2010

    • Author(s)
      Kakinuma Y, Furihata M, Akiyama T, Arikawa M, Handa T, Katare RG, Sato T
    • Journal Title

      J Mol Cell Cardiol

      Volume: 48 Pages: 680-693

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model.2010

    • Author(s)
      Kakinuma Y, Furihata M, Akiyama T, Arikawa M, Handa T, Katare RG, Sato T.
    • Journal Title

      J Mol Cell Cardiol. 48

      Pages: 680-693

    • NAID

      120002069739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Differential regulation of TNF receptors by vagal nerve stimulation protect heart against acute ischemic injury.2010

    • Author(s)
      Katare RG, Ando M, Kakinuma Y, Arikawa M, Yamasaki F, Sato T.
    • Journal Title

      J Mol Cell Cardiol. 49

      Pages: 234-244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Differential regulation of TNF receptors by vagal nerve stimulation protect heart against ccute ischemic injury.2010

    • Author(s)
      Katare RG, Ando M, Kakinuma Y, Arikawa M, Yamasaki F, Sato T.
    • Journal Title

      J Mol Cell Cardiol.

      Volume: 49 Pages: 234-244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model.2010

    • Author(s)
      Kakinuma Y, Furihata M, Akiyama T, Arikawa M, Handa T, Katare RG, Sato T.
    • Journal Title

      J Mol Cell Cardiol.

      Volume: 48 Pages: 680-693

    • NAID

      120002069739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Engineered heart tissue : A novel tool to study the ischemic changes of the heart In vitro.2010

    • Author(s)
      Katare RG, Ando M, Kakinuma Y, Sato T
    • Journal Title

      PLoS ONE

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Differential regulation of TNF receptors by vagal nerve stimulation protects heart against acute ischemic injury.2010

    • Author(s)
      Katare RG, Ando M, Kakinuma Y, et al.
    • Journal Title

      Journal of Molecular and Cellular Cardiology

      Volume: 49 Pages: 234-244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model.2010

    • Author(s)
      Kakinuma Y, Furihata M, et al.
    • Journal Title

      Journal of Molecular and Cellular Cardiology

      Volume: 48 Pages: 680-693

    • NAID

      120002069739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Engineered heart tissue : a novel tool to study the ischemic changes of the heart in vitro2010

    • Author(s)
      Katare RG, Ando M, Kakinuma Y, Sato T
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Differential regulation of TNF receptors by vagal nerve stimulation protects heart against acute ischemic injury2010

    • Author(s)
      Katare RG, Ando M, Kakinuma Y, Arikawa M, Yamasaki F, Sato T
    • Journal Title

      J Mol Cell Cardiol

      Volume: 49 Pages: 234-244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Engineered heart tissue : A novel tool to study the ischemic changes of the heart In vitro.2010

    • Author(s)
      Katare RG, Ando M, Kakinuma Y, Sato T.
    • Journal Title

      PLoS ONE 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model2010

    • Author(s)
      Kakinuma Y
    • Journal Title

      J Molecular and Cellular Cardiology 48

      Pages: 680-693

    • NAID

      120002069739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Donepezilを使用した容量負荷心不全マウスにおける心機能改善効果2009

    • Author(s)
      半田武巳、Katare GR、柿沼由彦、有川幹彦、安藤元規、山崎文靖、佐藤隆幸、篠栗志朗
    • Journal Title

      生存率改善効果の検討心臓

      Volume: 41 Pages: 115-123

    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal efferent effects in sparsely innervated ventricular myocardium2009

    • Author(s)
      Kakinuma Y
    • Journal Title

      FEBS J 276

      Pages: 5111-5125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Vagal nerve stimulation prevents reperfusion injury through inhibition of opening of mitochondrial permeability transition pore independent of the bradycardiac effect.2009

    • Author(s)
      Katare RG, Ando M, Kakinuma Y, Arikawa M, Handa T, Yamasaki F, Sato T.
    • Journal Title

      J Thorac Cardiovasc Surg. 137

      Pages: 223-231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway.2009

    • Author(s)
      Katare RG, Kakinuma Y, Arikawa M, Yamasaki F, Sato T.
    • Journal Title

      J Mol Cell Cardiol. 46

      Pages: 405-412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Anti-Alzheimer's drug, donepezil, markedly improves long-term survival after chronic heart failure in mice.2009

    • Author(s)
      Handa T, Katare RG, Kakinuma Y, Arikawa M, Ando M, Sasaguri S, Yamasaki F, Sato T.
    • Journal Title

      J Card Fail. 15

      Pages: 805-811

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Anti-Alzheimer' s drug, donepezil, markedly improves long-term survival after chronic heart failure in mice2009

    • Author(s)
      Handa T, Katare RG, Kakinuma Y, Arikawa M, Ando M, Sasaguri S, Yamasaki F, Sato T
    • Journal Title

      J Card Fail

      Volume: 15 Pages: 805-811

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Vagal nerve stimulation prevents reperfusion injury through inhibition of opening of mitochondrial permeability transition pore independent of the bradycardiac effect2009

    • Author(s)
      Katare GR, Ando M, Kakinuma Y, Arikawa M, Handa T, Yamasaki F, Sato T
    • Journal Title

      J Thorac Cardiovasc Surgery 137

      Pages: 223-231

    • Data Source
      KAKENHI-PROJECT-19590251
  • [Journal Article] Vagal nerve stimulation prevents reperfusion injury through inhibition of opening of mitochondrial permeability transition pore independent of the bradycardiac effect2009

    • Author(s)
      Katare GR, Ando M, Kakinuma Y, Arikawa M, Handa T, Yamasaki F, Sato T
    • Journal Title

      J Thorac Cardiovasc Surgery

      Volume: 137 Pages: 223-231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal efferent effects in sparsely innervated ventricular myocardium.2009

    • Author(s)
      Kakinuma Y, Akiyama T, Sato T.
    • Journal Title

      FEBS J.

      Volume: 276 Pages: 5111-5125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Donepezilを使用した容量負荷心不全マウスにおける心機能改善効果、生存率改善効果の検討2009

    • Author(s)
      半田武巳、Katare GR、柿沼由彦, 有川幹彦、安藤元規、山崎文靖、佐藤隆幸、篠栗志朗
    • Journal Title

      心臓 41(2)

      Pages: 115-123

    • NAID

      130003376859

    • Data Source
      KAKENHI-PROJECT-19590251
  • [Journal Article] Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal efferent effects in sparsely innervated ventricular myocardium2009

    • Author(s)
      Kakinuma Y, Akiyama T, Sato T
    • Journal Title

      FEBS J

      Volume: 276 Pages: 5111-5125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] Anti-Alzheimer's drug. donepezil. markedly improves long-term survival after chronic heart failure in mice.2009

    • Author(s)
      Handa T., Katare RG., Kakinuma Y., Arikawa M., Ando M., Sasaguri S., Yamasaki F., Sato T.
    • Journal Title

      J Card Fail.

      Volume: 15 Pages: 805-811

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal efferent effects in sparsely innervated ventricular myocardium.2009

    • Author(s)
      Kakinuma Y, Akiyama T, Sato T.
    • Journal Title

      FEBS J. 276

      Pages: 5111-5125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Journal Article] Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway2009

    • Author(s)
      Katare GR, Kakinuma Y, Arikawa M, Yamasaki F, Sato T.
    • Journal Title

      J Mol Cel Cardiol 46

      Pages: 405-412

    • Data Source
      KAKENHI-PROJECT-19590251
  • [Journal Article] Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/ VEGF/ PI3K signaling pathway2009

    • Author(s)
      Katare GR, Kakinuma Y, Arikawa M, Yamasaki F, Sato T
    • Journal Title

      J Mol Cell Cardiol

      Volume: 46 Pages: 405-412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Journal Article] A HIF-1alpha-related gene involved in cell protection from hypoxia by suppression of mitochondrial function2008

    • Author(s)
      Kakinuma Y, Katare RG, Arikawa M, Muramoto K, Yamasaki F, Sato T
    • Journal Title

      FEBS Lett 582

      Pages: 332-340

    • NAID

      120002069742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Journal Article] Acute Inactivation of the VHL gene Contributes to Protective Effects of Ischemic Preconditioning in the Mouse Kidney2008

    • Author(s)
      Iguchi M, Kakinuma Y, Kurabayashi A, Sato T, Shuin T, Hong S-B, Schmidt LS, Furihata M
    • Journal Title

      Nephron, Nephron Exp Nephrol 110

    • NAID

      120002069740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Journal Article] A HIF-1alpha-related gene involved in cell protection from hypoxia by suppression of mitochondrial function2007

    • Author(s)
      Kakinuma, Y
    • Journal Title

      FEBS Lett 582

      Pages: 332-340

    • NAID

      120002069742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Journal Article] Estrogen is involved in improvement of impaired cardiac glucose uptake in cancer patients

    • Author(s)
      Yoshihiko Kakinuma, Shoshiro Okada, Nobuo Ikenoue, Munenobu Nogami, Yoshitaka Kumon
    • Journal Title

      Journal of Cardiology Cases

      Volume: (in press)(in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590678
  • [Patent] Functional foods containing bonito-derived extracts to prevent or improve neuropsychiatric disorders2023

    • Inventor(s)
      Hokari Y, Sekine A, Kakinuma Y
    • Industrial Property Rights Holder
      Hokari Y, Sekine A, Kakinuma Y
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21K11658
  • [Patent] 脂質タンパク質複合体を含む多検体試料を分析するための電気泳動用スラブ型ポリアクリルアミドゲル及びその方法2022

    • Inventor(s)
      竹中 康浩、井上 郁夫、柿沼 由彦
    • Industrial Property Rights Holder
      竹中 康浩、井上 郁夫、柿沼 由彦
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-001983
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Patent] Functional foods containing bonito-derived extracts to prevent or improve neuropsychiatric disorders2022

    • Inventor(s)
      保苅 義則・柿沼 由彦
    • Industrial Property Rights Holder
      マルハチ村松株式会社・日本医科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21K11658
  • [Patent] 生体内NO産生装置2018

    • Inventor(s)
      柿沼由彦、人見雄一、渡辺正広、長尾佳文
    • Industrial Property Rights Holder
      柿沼由彦、人見雄一、渡辺正広、長尾佳文
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-034042
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Patent] 心臓アセチルコリン産生能誘導薬2018

    • Inventor(s)
      柿沼由彦、中村成夫
    • Industrial Property Rights Holder
      柿沼由彦、中村成夫
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-185112
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Patent] 生体内NO産生装置2018

    • Inventor(s)
      柿沼 由彦
    • Industrial Property Rights Holder
      柿沼 由彦
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] マウス心筋細胞および非心筋細胞のトランスクリプトーム解析:個体老化における増殖停止細胞と増殖性細胞の比較2023

    • Author(s)
      竹中 康浩、平崎 正孝、井上 郁夫、池田 正明、大畠 久幸、柿沼 由彦
    • Organizer
      日本生理学会第100回記念大会
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Presentation] Dried bonito-derived extract regulates inflammatory responses in the central nervous system and blood brain barrier, associated with the modification of the cholinergic system2023

    • Author(s)
      Hokari Y, Sekine A, Kai Y, Oikawa S, Mano A, Ohata H, Sugama S, Kakinuma Y
    • Organizer
      日本生理学会第100回記念大会
    • Data Source
      KAKENHI-PROJECT-21K11658
  • [Presentation] 個体老化における増殖停止細胞(心筋細胞)と増殖性細胞(非心筋細胞)のトランスクリプトーム解析2023

    • Author(s)
      竹中 康浩、平崎 正孝、井上 郁夫、池田 正明、大畠 久幸、柿沼 由彦
    • Organizer
      第46回日本基礎老化学会大会
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Presentation] Transcriptomic analyses of mouse cardiac myocytes and cardiac non-myocyte cells: postmitotic vs. proliferative cells2023

    • Author(s)
      Yasuhiro Takenaka, Masataka Hirasaki, Ikuo Inoue, Masaaki Ikeda, Yoshihiko Kakinuma
    • Organizer
      第100回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Presentation] 増殖停止細胞の老化を解き明かす:トランスクリプトーム解析による老齢マウス心筋細胞の核小体低分子RNA(snoRNA)とミトコンドリア遺伝子発現2023

    • Author(s)
      竹中 康浩、平崎 正孝、井上 郁夫、池田 正明、大畠 久幸、柿沼 由彦
    • Organizer
      第46回日本分子生物学会大会
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Presentation] タンパク質恒常性(プロテオスタシス)の視点から見たストレス誘導性細胞老化とその制御:ミトコンドリア代謝の重要性2023

    • Author(s)
      竹中 康浩、井上 郁夫、平崎 正孝、池田 正明、柿沼 由彦
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Presentation] 後肢虚血-再灌流は肝細胞でのGLUT4蛋白発現とその細胞膜移行を促進することでglycogenの蓄積をもたらす2022

    • Author(s)
      倉林 睦、降幡 薫、岩下和花、田中千遥、降幡睦夫、柿沼由彦
    • Organizer
      第65回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K07483
  • [Presentation] Vitamin E and rapamycin treatment attenuate cellular senescence induced by prolonged disturbance of proteostasis in human fibroblasts2022

    • Author(s)
      Yasuhiro Takenaka, Ikuo Inoue, Masaaki Ikeda, Yoshihiko Kakinuma
    • Organizer
      第99回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-21K11605
  • [Presentation] 後肢虚血―再灌流刺激の糖尿病ケトアシドーシスに対する抑止効果とそのメカニズムの検討2020

    • Author(s)
      倉林睦 , 岩下和花 , 田中千遥 , 長沼誠二 , 降幡睦夫, 柿沼由彦
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K07483
  • [Presentation] 後肢―再灌流刺激の糖尿病ケトアシドーシスに対する抑止効果とそのメカニズムの検討2020

    • Author(s)
      倉林 睦、岩下和花、田中千遥、長沼誠二、降幡睦夫、柿沼由彦
    • Organizer
      第63回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K07483
  • [Presentation] Remote ischemic preconditioning affects gluconeogenesis via the brain-liver route to improve glucose intolerance2019

    • Author(s)
      Kurabayashi A, Kakinuma Y
    • Organizer
      9th Federation of the Asian and Oceanian Physiological Societies
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] 心臓非神経性ACh産生システムの臓器間クロストークとその生理機能学的意味2018

    • Author(s)
      柿沼 由彦
    • Organizer
      第28回日本病態生理学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] Modified regulation in the non-neuronal acetylcholine in the heart (NNCCS) by circadian rhythmicity and sexual dimorphism2018

    • Author(s)
      Kakinuma Y, Oikawa S, Kai Y, Mano A, Ohata H, Nemoto K
    • Organizer
      第95回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] Stress-induced microglial activation nullified in b1 and b2 adrenergic receptor double knockout mice2018

    • Author(s)
      Sugama S, Kakinuma Y
    • Organizer
      The 95th Annual Meeting of the Physiological Society Meeting
    • Data Source
      KAKENHI-PROJECT-15K06783
  • [Presentation] A stress-refractory propensity in the CNS is provided by augmented non-neuronal cardiac cholinergic system via the vagus nerve to acquire.2017

    • Author(s)
      Kakinuma Y, Oikawa S, Kaki Y, Tsuda M, Ohata H, Mano A, Mizoguchi N, Sugama S, Nemoto T, Suzuki K, Kurabayashi A, Muramoto K, Kaneda M.
    • Organizer
      第81回日本循環器学会学術集会
    • Place of Presentation
      石川県立音楽堂他
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] Non-neuronal cardiac cholinergic system induces central anti-stress responses.2017

    • Author(s)
      Kakinuma Y, Oikawa S, Kaki Y, Tsuda M, Ohata H, Mano A, Mizoguchi N, Sugama S, Nemoto T, Suzuki K, Kurabayashi A, Muramoto K, Kaneda M.
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      浜松アクトシティコングレスセンター
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] Loss of dopaminergic neuronss occurs in the ventral tegmental area and hypothalamus of rats following chronic stress: Possible pathogenetic loci for depression involved in Parkinson's disease2017

    • Author(s)
      Sugama S, Kakinuma Y
    • Organizer
      日本生理学会
    • Place of Presentation
      浜松市
    • Year and Date
      2017-03-28
    • Data Source
      KAKENHI-PROJECT-15K06783
  • [Presentation] 心筋自らがもつACh産生系 non-neuronal cardiac cholinergic systemとその脳心連関のもつ意義2017

    • Author(s)
      柿沼 由彦
    • Organizer
      第137回 日本薬理学会関東部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] 後肢虚血―再灌流刺激の肝糖代謝への影響と中枢神経を介したそのメカニズム2017

    • Author(s)
      倉林 睦, 田中千遥, 松本和花, 長沼誠二, 降幡睦夫,柿沼由彦
    • Organizer
      日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-15K08427
  • [Presentation] 心筋自らがもつACh産生系 non-neuronal cardiac cholinergic systemとその脳心連関のもつ意義2017

    • Author(s)
      柿沼 由彦
    • Organizer
      横浜市立大学大学院医学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] 循環器領域におけるNNA (non-neuronal ACh)の関与の可能性2016

    • Author(s)
      柿沼 由彦
    • Organizer
      第9回運動循環器病学研究会
    • Place of Presentation
      大田区産業プラザPio
    • Year and Date
      2016-02-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Presentation] 心臓自らが作り出すAChとは何か(a non-neuronal cardiac cholinergic system NNCCSの発見)2016

    • Author(s)
      柿沼由彦
    • Organizer
      第4回取手・守谷地区循環器講演会
    • Place of Presentation
      デュープレックスセミナーホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] a non-neuronal cardiac cholinergic system (NNCCS)のモデルマウス から見えてきたもの2016

    • Author(s)
      柿沼由彦
    • Organizer
      第18回旭川心血管リモデリング研究会学術講演会
    • Place of Presentation
      旭川医科大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] Elevation of blood pressure in F2 offspring of dams delivered from carbohydrate-restriction during pregnancy2016

    • Author(s)
      根本 崇宏、柿沼 由彦
    • Organizer
      第93回日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-03-22
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Presentation] Chronic restraint stress triggers the dopaminergic and noradrenergic neurodegeneration-possible role of chronic stress in the onset of Parkinson's disease2016

    • Author(s)
      洲鎌 秀永、柿沼 由彦
    • Organizer
      第93回日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-03-22
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Presentation] Remote ischemic preconditioning with a specialized protocol activates the non-neuronal cardiac cholinergic system and increases ATP content in the heart2016

    • Author(s)
      柿沼 由彦、及川詩乃、眞野 あすか
    • Organizer
      第93回日本生理学会大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-03-22
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Presentation] Chronic restraint stress triggers the dopaminergic and noradrenergic neurodegeneration-possible role of chronic stress in the onset of Parkinson's disease2016

    • Author(s)
      Sugama S, Kakinuma K
    • Organizer
      日本生理学会
    • Place of Presentation
      札幌市
    • Year and Date
      2016-03-22
    • Data Source
      KAKENHI-PROJECT-15K06783
  • [Presentation] 循環器領域においてa non-neuronal cholinergic systemが意味するもの2016

    • Author(s)
      柿沼由彦
    • Organizer
      長崎循環器疾患連携セミナー
    • Place of Presentation
      長崎ワシントンホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08560
  • [Presentation] Another pathophysiological aspect of stress-related cardiomyopathy  Glucose could be a therapeutic target for stress-induced cardiomyopathy?2014

    • Author(s)
      柿沼由彦
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島大学郡元キャンパス
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Presentation] 細胞内コリン作動系制御機構を介した細胞代謝とその病態への影響.2013

    • Author(s)
      柿沼 由彦、津田 正之、岡崎 佳代、秋山 剛、有川 幹彦、野口達哉、佐藤 隆幸.
    • Organizer
      第34回日本循環制御医学会総会
    • Place of Presentation
      福井県県民ホール
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] 細胞内コリン作動系制御機構を介した細胞代謝とその病態への影響2013

    • Author(s)
      柿沼 由彦
    • Organizer
      第34回日本循環制御医学会総会
    • Place of Presentation
      福井県民ホール, 福井市
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] 非神経性心臓コリン作働システムの温故知新2013

    • Author(s)
      柿沼由彦
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      タワーホール船堀(東京都)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] たこつぼ心筋症と性差2013

    • Author(s)
      柿沼由彦
    • Organizer
      第66回日本自律神経学会総会
    • Place of Presentation
      愛知県産業労働センターウインクあいち
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460333
  • [Presentation] 非神経性コリン作働システムの温故知新-このシステムを利用した代謝制御インターベンションの可能性2013

    • Author(s)
      柿沼 由彦
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      タワーホール船堀, 東京都
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] 非神経性心臓コリン作働系はエネルギー代謝を抑制的に制御する2012

    • Author(s)
      柿沼 由彦
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      松本文化会館, 長野県松本市
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] Cholinoceptive cholinerg ic properties of cardiomyocytes : Amp lification mechanism for vagal effer ent effects2012

    • Author(s)
      Kakinuma Y
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡国際会議場,福岡市
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] Donepezil, an Acetylcholinesterase Inhibitor, Prevents Cardiac Rupture during Acute Phase of Myocardial Infarction in Mice2012

    • Author(s)
      Arikawa M, Kakinuma Y, et al
    • Organizer
      第76回日本循環器学会学術総会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] トピックス2非薬物的自律神経介入治療の最前線Cholinoceptive Cholinergic Properties of Cardiomyocytes : Amplification Mechanism for Vagal Efferent Effects2012

    • Author(s)
      柿沼由彦
    • Organizer
      第76回日本循環器学会学術総会
    • Place of Presentation
      福岡国際会議場福岡
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Donepezil prevents cardiac rupture during acute phase of myocardial infarction in mice2012

    • Author(s)
      Arikawa M, KakinumaY, Noguchi T, Sato T
    • Organizer
      第89回日本生理学会大会長野県松本市文化会館
    • Place of Presentation
      長野
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] A non-neuronal cardiac cholinergic system(nNCCS) in cardiomyocytes plays a role in suppressing overshooting energy metabolism2012

    • Author(s)
      Kakinuma Y
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      松本文化会館(長野県)
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] A non-neuronal cardiac cholinergic system(nNCCS) in cardiomyocytes plays a role in suppressing overshooting energy metabolism2012

    • Author(s)
      Kakinuma Y, Akiyama T, Sato T
    • Organizer
      第89回日本生理学会大会長野県松本市文化会館
    • Place of Presentation
      長野
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Donepezil, an Acetylcholinesterase Inhibitor, Prevents Cardiac Rupture during Acute Phase of Myocardial Infarction in Mice2012

    • Author(s)
      Arikawa M, Kakinuma Y, Noguchi T, Yamasaki F, Satoh T
    • Organizer
      第76回日本循環器学会学術総会
    • Place of Presentation
      福岡国際会議場福岡
    • Year and Date
      2012-03-17
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Donepezil prevents cardiac rupture during acute phase of myocardial infarction in mice2012

    • Author(s)
      Arikawa M, Kakinuma Y, Noguchi T, Sato T
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      長野県松本文化会館(長野県)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] 非薬物的自律神経介入治療の最前線:Cholinoceptive Cholinergic Properties of Cardiomyocytes : Amplification Mechanism for Vagal Efferent Effects2012

    • Author(s)
      Kakinuma Y
    • Organizer
      第76回日本循環器学会学術総会
    • Place of Presentation
      福岡国際会議場(福岡県)(招待講演)
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] A non-neuronal cardiac cholinergic System(nNCCS) in cardiomyocytes plays a role in suppressing overshooting energy metabolism2012

    • Author(s)
      Kakinuma Y, Akiyama T, Sato T
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      長野県松本文化会館(長野県)
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] 非薬物的自律神経介入治療の最前線Cholinoceptive Cholinergic Properties of Cardiomyocytes : Amplification Mechanism for Vagal Efferent Effects2012

    • Author(s)
      柿沼由彦
    • Organizer
      第76回日本循環器学会学術総会
    • Place of Presentation
      福岡国際会議場(福岡県)(招待講演)
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Conditional VHL gene deletion activates a local NO-VEGF axis in a balanced fashion to reinforce resistance to endothelium-targeted glomerulonephropathy2011

    • Author(s)
      Morita T, Kakinuma Y, Kurabayashi A, Fujieda M, Sato T, Shuin T, Furihata M, Wakiguchi H
    • Organizer
      11^<th> Asian Congress of Pediatric Nephrology 2011
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] 心筋細胞内アセチルコリン産生系の生物学的意義2011

    • Author(s)
      柿沼由彦
    • Organizer
      第63回日本生理学会中国四国地方会
    • Place of Presentation
      広島大学(広島県)
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] Conditional VHL gene deletion activates a local NO-VEGF axis in a balanced fashion to reinforce resistance to endothelium-targeted glomerulonephropathy2011

    • Author(s)
      Morita T, Kakinuma Y, Kurabayashi A, Fujieda M, Sato T, Shuin T, Furihata M, Wakiguchi H
    • Organizer
      第46回日本小児腎臓病学会学術集会
    • Place of Presentation
      福岡国際会議場福岡
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Acetylcholinesterase Inhibitor Donepezil in Treatment of Myocardial Ischemia and Heart Failure2011

    • Author(s)
      Arikawa M, Kakinuma Y, Noguchi T, Sato T
    • Organizer
      ISAN/AAS2011 (Satellite Meeting)
    • Place of Presentation
      Rio de janeiro, Brasil
    • Year and Date
      2011-09-18
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Conditional VHL gene deletion activates a local NO-VEGF axis in a balanced fashion to reinforce resistance to endothelium-targeted glomerulonephropathy2011

    • Author(s)
      Morita T, Kakinuma Y, et al
    • Organizer
      11th Asian Congress of Pediatric Nephrology 2011
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Year and Date
      2011-06-04
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] 心筋細胞内アセチルコリン産生系の生物学的意義2011

    • Author(s)
      柿沼由彦, 秋山剛, 有川幹彦, 岡崎佳代, 佐藤隆幸
    • Organizer
      第63回日本生理学会中国四国地方会
    • Place of Presentation
      広島大学(広島県)
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Molecular mechanisms of muscular abnormality in transgenic mice overexpressing NF90, a dsRNA binding protein2011

    • Author(s)
      Sakamoto S, Higuchi T, Kakinuma Y, et al
    • Organizer
      16th Annual Meeting of the RNA Society
    • Place of Presentation
      京都国際会議場(京都府)
    • Year and Date
      2011-06-14
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] ドネペジルは、マウス心筋梗塞モデルにおいて、マクロファージMMP-9の産生を抑制することにより急性期心破裂の危険率を低減する2011

    • Author(s)
      有川幹彦, 柿沼由彦, 他
    • Organizer
      第12回Neurocardiology Workshop
    • Place of Presentation
      東京ステーションコンファレンス(東京都)
    • Year and Date
      2011-07-30
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] 心筋細胞内アセチルコリン産生系の生物学的意義2011

    • Author(s)
      柿沼由彦,秋山剛,有川幹彦,岡崎佳代,佐藤隆幸
    • Organizer
      第63回日本生理学会中国四国地方会
    • Place of Presentation
      広島大学
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] ドネペジルは、マウス心筋梗塞モデルにおいて、マクロファージMMP-9産生を抑制し急性期心破裂の危険率を低減する2011

    • Author(s)
      有川幹彦, 柿沼由彦, 野口達哉, 佐藤隆幸
    • Organizer
      第63回日本生理学会中国四国地方会
    • Place of Presentation
      広島大学(広島県)
    • Year and Date
      2011-10-23
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] 心筋細胞内アセチルコリン産生系の生物学的意義2011

    • Author(s)
      柿沼 由彦
    • Organizer
      第63回日本生理学会中国四国地方会
    • Place of Presentation
      広島大学, 広島市
    • Data Source
      KAKENHI-PROJECT-23300191
  • [Presentation] Beneficial Effects of Donepezil, an Acetylcholinesterase Inhibitor, on Heart Failure2011

    • Author(s)
      Kubo T, Kitaoka H, Kakinuma Y, Satoh T, Doi Y
    • Organizer
      第75回日本循環器学会学術総会
    • Place of Presentation
      パシフィコ横浜神奈川
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Acetylcholinesterase Inhibitor Donepezil in Treatment of Myocardial Ischemia and Heart Failure2011

    • Author(s)
      Arikawa M, Kakinuma Y, Noguchi T, Sato T
    • Organizer
      ISAN/ AAS2011(Satellite Meeting) Rio de janeiro
    • Place of Presentation
      Brasil
    • Year and Date
      2011-09-18
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] ドネペジルは、マウス心筋梗塞モデルにおいて、マクロファージMMP-9の産生を抑制することにより急性期心破裂の危険率を低減する2011

    • Author(s)
      有川幹彦、柿沼由彦、野口達哉、佐藤隆幸
    • Organizer
      第12回Neurocardiology Workshop東京ステーションコンファレンス
    • Place of Presentation
      東京都
    • Year and Date
      2011-07-30
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Beneficial Effects of Donepezil, an Acetylcholinesterase Inhibitor, on Heart Failure2011

    • Author(s)
      Kubo T, Kitaoka H, Kakinuma Y, Sato T, Doi Y
    • Organizer
      第75回日本循環器学会総会・学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-08-03
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] ドネペジルはマウス心筋梗塞モデルにおいて、マクロファージMMP-9産生を抑制し急性期心破裂の危険率を低減する2011

    • Author(s)
      有川幹彦,柿沼由彦,野口達哉,佐藤隆幸
    • Organizer
      第63回日本生理学会中国四国地方会
    • Place of Presentation
      広島大学
    • Year and Date
      2011-10-23
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Molecular mechanisms of muscular abnormality in transgenic mice overexpressing NF90, a dsRNA binding protein2011

    • Author(s)
      Sakamoto S, Higuchi T, Kakinuma Y, Kai S, Todaka H, Yagyu K, Obata E, Morisawa K, Fukushima A, Tsuda M, Taniguchi T
    • Organizer
      16^<th> Annual Meeting of the RNA Society
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-central and non-neuronal acetylcholine synthesis system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism.2010

    • Author(s)
      柿沼由彦
    • Organizer
      第31回日本循環制御医学会総会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府)
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] 塩酸ドネペジル内服による心血管系への影響に関する前向き登録調査研究2010

    • Author(s)
      久保亨、西永正典、柿沼由彦、佐藤隆幸、土居義典
    • Organizer
      第11回Neurocardiology Workshop
    • Place of Presentation
      東京ステーションコンファレンス
    • Year and Date
      2010-07-31
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-neuronal cholinergic system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism.2010

    • Author(s)
      Kakinuma Y
    • Organizer
      19th International Conference of the Cardiovascular System Dynamics Society
    • Place of Presentation
      Kyusyu University (Fukuoka)
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] The new era of therapeutic modalities against heart failure, focusing on pharmacological intervention of the cardiovascular cholinergic system.2010

    • Author(s)
      柿沼由彦
    • Organizer
      19th International Conference of the Cardiovascular System Dynamics Society
    • Place of Presentation
      Fukuoka, Kyusyu University.
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] 非中枢性細胞内アセチルコリン産生系がもつ多様な生物学的意義について2010

    • Author(s)
      柿沼由彦
    • Organizer
      第5回 旭川医科大学脈管クラスター研究会
    • Place of Presentation
      旭川医科大学(北海道)
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] アセチルコリンのpleiotrophic actionから心筋内アセチルコリン産生系まで2010

    • Author(s)
      柿沼由彦
    • Organizer
      第63回日本自律神経学会総会
    • Place of Presentation
      ワークピア横浜
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] 心筋細胞内アセチルコリン産生系の生物学的意義2010

    • Author(s)
      柿沼由彦
    • Organizer
      第11回 Neurocardiology Workshop
    • Place of Presentation
      東京ステーションコンファレンス(東京)
    • Year and Date
      2010-07-31
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-neuronal cholinergic system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism2010

    • Author(s)
      Kakinuma Y, Akiyama T, Arikawa M, Sato T
    • Organizer
      19^<th> International Conference of the Cardiovascular System Dynamics Society
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] 心筋細胞内アセチルコリン産生系の生物学的意義2010

    • Author(s)
      柿沼由彦
    • Organizer
      第11回Neurocardiology Workshop
    • Place of Presentation
      東京ステーションコンファレンス
    • Year and Date
      2010-07-31
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Donepezil, an acetylcholinesterase inhibitor, reduces the risk of left ventricular free wall rapture during an acute phase of myocardial infarction by attenuating macrophage matrix metalloproteinase-92010

    • Author(s)
      Arikawa M, Kakinuma Y, Yamasaki F, Sato T
    • Organizer
      19^<th> International Conference of the Cardiovascular System Dynamics Society
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] 非中枢性細胞内アセチルコリン産生系がもつ多様な生物学的意義について2010

    • Author(s)
      柿沼由彦
    • Organizer
      第5回旭川医科大学脈管クラスター研究会
    • Place of Presentation
      旭川医科大学
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-central and non-neuronal acetylcholine synthesis system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism.2010

    • Author(s)
      柿沼由彦
    • Organizer
      第31回日本循環制御医学会総会
    • Place of Presentation
      大阪府千里ライフサイエンスセンター
    • Year and Date
      2010-05-29
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] The new era of therapeutic modalities against heart failure, focusing on pharmacological intervention of the cardiovascular cholinergic system2010

    • Author(s)
      Kakinuma Y, Sato T
    • Organizer
      19^<th> International Conference of the Cardiovascular System Dynamics Society
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-neuronal acetylcholine synthesis system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism.2010

    • Author(s)
      柿沼由彦
    • Organizer
      第74回日本循環器学会総会・学術集会
    • Place of Presentation
      京都市国立京都国際会館
    • Year and Date
      2010-03-06
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] Effects of a non-neuronal acetylcholine synthesis system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism2010

    • Author(s)
      Kakinuma Y, Akiyama T, Arikawa M, Handa T, Sato T
    • Organizer
      第74回日本循環器学会学術総会
    • Place of Presentation
      京都国際会議場
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-central and non-neuronal acetylcholine synthesis system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism.2010

    • Author(s)
      Kakinuma Y
    • Organizer
      第31回日本循環制御医学会総会
    • Place of Presentation
      千里ライフセンター(大阪)
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-neuronal acetylcholine synthesis system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism.2010

    • Author(s)
      Kakinuma Y
    • Organizer
      第74回日本循環器学会総会・学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2010-03-06
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] アセチルコリンのpleiotrophic actionから心筋内アセチルコリン産生系まで2010

    • Author(s)
      柿沼由彦
    • Organizer
      第63回日本自律神経学会総会
    • Place of Presentation
      ワークピア横浜(神奈川)
    • Year and Date
      2010-10-22
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] The new era of therapeutic modalities against heart failure, focusing on pharmacological intervention of the cardiovascular cholinergic system.2010

    • Author(s)
      Kakinuma Y
    • Organizer
      19th International Conference of the Cardiovascular System Dynamics Society
    • Place of Presentation
      Kyusyu University (Fukuoka)
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] The new era of therapeutic modalities against heart failure, focusing on pharmacological intervention of the cardiovascular cholinergic system.2010

    • Author(s)
      Kakinuma Y
    • Organizer
      19th International Conference of the Cardiovascular System Dynamics Society
    • Place of Presentation
      Kyushu University (Fukuoka)
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-central and non-neuronal acetylcholine synthesis system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism2010

    • Author(s)
      Kakinuma Y, Akiyama T, Arikawa M, Handa T, Sato T
    • Organizer
      第31回日本循環制御医学会総会
    • Place of Presentation
      千里ライフセンター大阪
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-neuronal cholinergic system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energymetabolism.2010

    • Author(s)
      Kakinuma Y
    • Organizer
      19th International Conference of the Cardiovascular System Dynamics Society
    • Place of Presentation
      Kyushu University (Fukuoka)
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-central and non-neuronal acetylcholine synthesis system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism2010

    • Author(s)
      Kakinuma Y
    • Organizer
      第74回日本循環器学会学術総会
    • Place of Presentation
      京都国際会館(京都)
    • Year and Date
      2010-03-06
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Effects of a non-neuronal cholinergic system equipped for cardiomyocytes, as a molecular brake, on overshooting cardiac energy metabolism.2010

    • Author(s)
      柿沼由彦
    • Organizer
      19th International Conference of the Cardiovascular System Dynamics Society
    • Place of Presentation
      Fukuoka, Kyusyu University.
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] VHL遺伝子不活性化によるマウス虚血再潅流障害の抑制2009

    • Author(s)
      森田拓、井口みつこ、柿沼由彦、倉林睦、藤枝幹也、脇口宏、執印太郎、佐藤隆幸、降幡睦夫
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Donepezil, an Acetylcholinesterase Inhibitor Against Alzheimers Dementia, Prevents Remodeling in Volume-Overload Heart Failure Mice : Local and Central effect of Donepezil2009

    • Author(s)
      Handa T, Sato T, Kakinuma Y, Arikawa M, Sasaguri S
    • Organizer
      第73回日本循環器学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Donepezil, an Acetylcholinesterase Inhibitor Against Alzheimers Dementia, Prevents Remodeling in Volume-Overload Heart Failure Mice : Local and Central effect of Donepezil2009

    • Author(s)
      Handa T, Sato T, Kakinuma Y, Arikawa M, Sasaguri S
    • Organizer
      第73回日本循環器学会学術総会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-21590283
  • [Presentation] Donepezil, Anti-Alzheimer's Disease Drug, Prevented the Progression of Ventricular Dysfunction after Myocardial Infarction2008

    • Author(s)
      Arikawa M, Katare R, Kakinuma Y, Handa T, Andoh M,Yamasaki F, Sato T
    • Organizer
      第72回日本循環器学会学術総会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] HIF-lalphaにより制御される新規因子は, ミトコンドリア転写因子を介してその機能を抑制し, 細胞を低酸素から保護する2008

    • Author(s)
      柿沼由彦
    • Organizer
      第9回Neurocardiology Workshop
    • Place of Presentation
      東京都, 東京ステーションコンファレンス
    • Year and Date
      2008-07-26
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] Cardiomyocytes produces acethylcholine in response to muscarinic receptor stimulation : A possible mechanism for amplification of cardioprotective effects of cardiac vagal nerve.2008

    • Author(s)
      Kakinuma Y
    • Organizer
      American Heart Association Scientific sessions 2008
    • Place of Presentation
      New Orleans USA
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] HIF-1alphaにより制御される新規因子は,ミトコンドリア転写因子を介してその機能を抑制し,細胞を低酸素から保護する2008

    • Author(s)
      柿沼由彦
    • Organizer
      第9回Neurocardiology Workshop
    • Place of Presentation
      東京都 東京ステーションコンファレンス
    • Year and Date
      2008-07-26
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] Cardiomyocytes Produces Acetylcholine in Circulation Response to Muscarinic Receptor Stimulation : a Possible Mechanism for Amplification of Cardioprotective Effects of Cardiac Vagal Nerve Circulation 116 : II-159(819)2008

    • Author(s)
      Kakinuma Y, Akiyama T, Arikawa M, Handa T, Sato T.
    • Organizer
      Scientific Session 2008 American Heart Association
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Cardiomyocytes produces acethylcholine in response to muscarinic receptor stimulation : A possible mechanism for amplification of cardioprotective effects of cardiac vagal nerve.2008

    • Author(s)
      柿沼由彦
    • Organizer
      American Heart Association Scientific sessions 2008
    • Place of Presentation
      New Orleans USA.
    • Year and Date
      2008-11-12
    • Data Source
      KAKENHI-PROJECT-20300177
  • [Presentation] Donepezil, an Acetylcholinesterase Inhibitor Against Alzheimers Dementia, Prevents Remodeling and Improves Survival in Volume-Overload Heart Failure Mice2008

    • Author(s)
      Handa T, Sato T, Kakinuma Y, Arikawa M.
    • Organizer
      第72回日本循環器学会学術総会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Cardiomyocytes Produces Acetylcholine in Response to Muscarinic Receptor Stimulation : a Possible Mechanism for Amplification of Cardioprotective Effects of Cardiac Vagal Nerve2008

    • Author(s)
      Kakinuma, Y
    • Organizer
      Scientific Session 2008 American Heart Association
    • Place of Presentation
      New Orleans, Louisiana, USA.
    • Year and Date
      2008-11-12
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] A HIF-1α-related gene involved in cell protection from hypoxia by suppression of mitochondrial function.2008

    • Author(s)
      Kakinuma, Y
    • Organizer
      第9回Neurocardiology Workshop
    • Place of Presentation
      東京都, 東京ステーションコンファレンス
    • Year and Date
      2008-07-26
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] A HIF-1α-related gene involved in cell protection from hypoxia by suppression of mitochondrial function2008

    • Author(s)
      Kakinuma Y, Sato T.
    • Organizer
      第9回 Neurocardiology Workshop
    • Place of Presentation
      東京ステーションコンファレンス
    • Year and Date
      2008-07-26
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Nitric Oxide Has Beneficial Effects on Cardiomyocytes by Activation of the Vascular Endothelial Growth Factor2007

    • Author(s)
      Kuwabara M, Kakinuma Y, Andoh M, Katare R, Yamasaki F, Doi Y, Sato T.
    • Organizer
      第71回日本循環器学会学術総会
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Myocardial Infarction is Prevented by Anti-Alzheimer's Disease Drug, Donepezil Circulation 116 : II-291(1416)2007

    • Author(s)
      7.Arikawa M, Katare GR, Kakinuma Y, Handa T, Ando M, Yamasaki F, Sato T.
    • Organizer
      Scientific Session 2007 American Heart Association
    • Place of Presentation
      Orland, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Donepezil Promotes Angiogenesis in an Ischemic Limb Model of Nicotinic α7 Receptor KO Mice2007

    • Author(s)
      Kakinuma Y, Katare GR, Arikawa M, Handa T, Yamsaki F, Sato T.
    • Organizer
      第8回Neurocardiology Workshop
    • Place of Presentation
      経団連会館
    • Year and Date
      2007-07-21
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Acetylcholiesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic limb model of nicotinic α7 KO mice2007

    • Author(s)
      Kakinuma, Y
    • Organizer
      American Heart Association Scientific Sessions 2007
    • Place of Presentation
      Orland, Florida, USA
    • Year and Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Tumor Necrosis Factor Receptor-2 Plays a Critical Role for Induction of Post Ischemic Neovascularization in Mouse Model of Hind Limb Ischemia. Circulation 116 : II-274(1339)2007

    • Author(s)
      Katare GR., Kakinuma Y, Arikawa M, Handa T, Yamasaki F, Sato T.
    • Organizer
      Scientific Session 2007 American Heart Association
    • Place of Presentation
      Orland, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Vagal Nerve Stimulation Salvage the Myocardium Agaisnt Reperfusion Injury Through Inhibition of Opening of Mitochondrial Permeability Transition Pore2007

    • Author(s)
      Katare R, Kakinuma Y, Andoh M, Arikawa M, Handa T, Sasaguri S, Yamasaki F, Sato T.
    • Organizer
      第71回日本循環器学会学術総会
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Donepezil promotes angiogenesis in an ischemic limb model of nicotinic alpha7 receptor KO mice2007

    • Author(s)
      Kakinuma, Y
    • Organizer
      第8回Neurocardiology Workshop
    • Place of Presentation
      東京
    • Year and Date
      2007-07-21
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Acetylcholiesterase Inhibitor Against Alzheimer's Dementia, Promotes Angiogenesis in an Ischemic Limb Model of Nicotinic α7 KO Mice Circulation 116 : II-159(819)2007

    • Author(s)
      Kakinuma Y, Katare GR, Arikawa M, Handa T, Yamasaki F, Li M, Zheng C, Sugimachi M, Sato T.
    • Organizer
      Scientific Session 2007 American Heart Association
    • Place of Presentation
      Orland, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Cardiomyocytes Produce Acetylcholine in Response to Muscarinic Receptor Agonists : a Possible Mechanism for Cardioprotective Effects of Vagal Stimulation on Cardiomyocytes2007

    • Author(s)
      Kakinuma Y, Katare R, Arikawa M, Handa T, Akiyama T, Andoh M, Yamasaki F, Sato T
    • Organizer
      第71回日本循環器学会学術総会
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Donepezil Promotes Angiogenesis through the Mechanisms Independent of Cholinesterase Inhibition and Nicotinic α7 Receptor2007

    • Author(s)
      Kakinuma Y, Katare R, Arikawa M, Handa T, Andoh M, Li M, Zheng C, Yamasaki F, Sato T.
    • Organizer
      第71回日本循環器学会学術総会
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Vagal Nerve Stimulation Protects Heart Against Ischemic Insult through Differential Regulation of Myocardial TNF Receptor Subtypes2007

    • Author(s)
      Katare R, Andoh M, Kakinuma Y, Arikawa M, Handa T, Yamasaki F, Sato T
    • Organizer
      第71回日本循環器学会学術総会
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Electrophysiological Approaches to the Mechanism of Arrhythmogenesis in Artificially-Arranged Cardiomyocytes2007

    • Author(s)
      Arikawa M, Katare R, Kakinuma Y, Andoh M, Handa T, Yamasaki F, Sato T.
    • Organizer
      第71回日本循環器学会学術総会
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] Cholinesterase Inhibitor Donepezil Improves Ventricular Function of Mice with Non-Ischemic Chronic Heart Failure2007

    • Author(s)
      Handa T, Katare R, Kakinuma Y, Arikawa M, Ando M, Sasaguri S, Sato T.
    • Organizer
      第71回日本循環器学会学術総会
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19590251
  • [Presentation] The fundamental significance of non-neuronal cardiac acetylcholine in terms of the pathophysiological conditions.

    • Author(s)
      Kakinuma Y
    • Organizer
      4th International Symposium on Non-neuronal Acetylcholine
    • Place of Presentation
      Justus-Liebig-University, Main Building, Giessen, Germany
    • Year and Date
      2014-08-28 – 2014-08-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460333
  • 1.  SATO Takayuki (90205930)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 75 results
  • 2.  ARIKAWA Mikihiko (20432817)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 54 results
  • 3.  NOGUCHI Tatsuya (50566495)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 12 results
  • 4.  YAMASAKI Fumiyasu (10243841)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 5.  Kurabayashi Atsushi (40346713)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 6.  Sugama Shuei (70302461)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 13 results
  • 7.  Takenaka Yasuhiro (20586789)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 8.  大畠 久幸 (80256924)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 9.  ZHENG Can (50443495)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  津田 雅之 (90406182)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 11.  井上 啓史 (00294827)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 12.  平崎 正孝 (10522154)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 13.  KAKINUMA Yoshihiko (60265866)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  HANDA Takemi (00437716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 15.  OSAKI Yasushi (20294829)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SHUIN TARO (70128601)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KARASHIMA Takashi (60304672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  ASHIDA Shingo (80380327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TAMURA Kenji (50464384)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SOGAWA Kazuhiro (80175421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  FURIHATA MUTSUO (10209158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 22.  TAKENOUCHI Takato (20292518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  HASHIMOTO Makoto (50189502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  KATARE RAJESH (20380313)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 16 results
  • 25.  公文 義雄 (40215033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 26.  岡田 尚志郎 (40203989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 27.  杉浦 哲朗 (50171145)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  福原 秀雄 (20527600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  山本 新九郎 (00793150)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  岩下 和花 (20830475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  降幡 薫 (10965461)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  曽野部 崇 (70548289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  Muramoto Kazuyo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 34.  Nemoto Takahiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 35.  Mano Asuka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 36.  Conti Bruno
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 37.  MIZOGUCHI Naoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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