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Kunugi Hiroshi  功刀 浩

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… Alternative Names

KUNUGI Hiroshi  功刀 浩

くぬ刀 浩  クヌキツ ヒロシ

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Researcher Number 40234471
Other IDs
Affiliation (Current) 2025: 帝京大学, 医学部, 教授
2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 疾病研究第三部, 客員研究員
Affiliation (based on the past Project Information) *help 2020 – 2024: 帝京大学, 医学部, 教授
2020 – 2021: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 疾病研究第三部, 客員研究員
2016 – 2019: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 疾病研究第三部, 部長
2015: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所疾病研究第三部, 部長
2013 – 2014: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第三部, 部長 … More
2010 – 2011: National Center of Neurology and Psychiatry, 神経研究所・疾病研究第三部, 部長
2010 – 2011: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第三部, 部長
2009: 国立精神・神経センター, 神経研究所, 部長
2009: 国立精神神経センター, 神経研究所, 部長
2009: National Center of Neurology and Psychiatry, 神経研究所 疾病研究第三部, 部長
2008: National Center of Neurology and Psychiatry, 神経研究所疾病研究第三部, 部長
2008: 国立精神神経センター
2008: 国立精神神経センター, 神経研究所 疾病研究第三部, 部長
2008: 獨協医科大学, 国立精神・神経センター神経研究所疾病研究第三部, 部長
2007: 神経研究所, 神経研究所・疾病研究第三部, 部長
2002 – 2005: Head, Department of Mental Disorder Research, National Center of Neurology and Psychiatry, 疾病研究第三部, 部長
2003: 国立精神・神経センター, 疾病研究第3部, 部長
2002: 国立精神・神経センター, 神経研究所, 部長
1997 – 2001: Teikyo Univ., Dept.of Psychiatry.Professor, 医学部, 講師
1996: 帝京大学, 医学部, 助手
1994: 帝京大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Psychiatric science / Psychiatric science
Except Principal Investigator
Psychiatric science / Basic Section 52030:Psychiatry-related / Psychiatric science / Biological Sciences / Basic Section 47060:Clinical pharmacy-related / Basic Section 33020:Synthetic organic chemistry-related / Sports science / 遺伝 / Biological pharmacy
Keywords
Principal Investigator
神経栄養因子 / 精神分裂病 / 統合失調症 / p75 / VGF / Neurodevelopment / Hippocampus / Schizophrenia / 関連研究 / ニューロトロフィン-3 … More / 脳由来神経栄養因子 / 海馬 / 分子遺伝学 / 脳脊髄液 / うつ病 / バイオマーカー / 脳神経疾患 / 神経科学 / キヌレニン / トリプトファン / 呼気ガス検査 / 安定同位体 / association study / polymorphism / Alzheimer's disease / schizophrenia / neurotrophin-3 / neurotrophic factor / 一塩基多型(SNP) / 遺伝子多型 / アルツハイマー病 / ニューロトロフィン3 / Ventricular enlargement / single nucleotide polymorphism / Glial cell derived neurotrophic factor / Brain-derived neurotrophic factor / Neueotrophic factor / 脳室拡大 / 一塩基多型 / グリア細胞由来神経栄養因子 / 神経発達障害 / Brain derived neurotrophic factor / Neurotrophin-3 / Molecular genetics / Neurotrophic factor / ヒューロトフロフィン3 / 神経発達 / 双極性障害 / マイクロRNA / ゲノム / プロテオミクス / バイオテクノロジー / 薬学 / 脳・神経 / 薬理学 / 遺伝子 / プレパルス抑制テスト / 知覚運動ゲイティング / マウス / モデル動物 / プレパスル抑制テスト … More
Except Principal Investigator
HLA / 統合失調症 / schizophrenia / うつ病 / 神経発達障害 / 分裂病 / 精神分裂病 / 分子遺伝学 / 相関研究 / ゲノムスキャン / CGHアレイ / 精神疾患 / VLDLR / ヒトiPS細胞由来脳関門細胞 / 3次元チップ / マイクロフィジオロジカルシステム / 血液脳脊髄液関門モデル細胞 / 血液脳関門モデル細胞 / ヒトiPS細胞 / ヒト不死化脳脊髄液関門細胞 / トランスポーター / ヒト脳脊髄液関門細胞 / ヒトiPS細胞由来脳毛細血管内皮細胞様細胞 / 3次元培養チップ / 血液脳関門 / 13C-呼気試験法 / Strecker反応 / 5-ヒドロキシトリプトファン / トリプトファン / 13C-呼気試験 / 13C-標識化合物 / 白質病変 / 脳脊髄液 / プレパルスインヒビション / 感覚フィルタリング機能障害 / プレパルスインヒビション(PPI) / sensorimotor gating障害 / モノアミン代謝産物 / 大うつ病性障害 / MHPG / HVA/5-HIAA / IFN-β / フィブリノーゲン / 脳脊髄液(CSF) / プレパルス抑制検査(PPI) / sensorimotor gating / リン脂質 / オートタキシン / リゾリン脂質 / 脂質メディエーター / グリア / リゾホスファチジン酸1受容体 / うつ病バイオマーカー / DHA-LPA / 抗うつ薬創薬 / LPA受容体 / 抗うつ薬受容体 / バイオマーカー / LPA1受容体 / 栄養療法 / 創薬 / 抗うつ薬 / リゾフォスファチジン酸受容体1 / リゾフォスファチジン酸 / リゾリン脂質代謝 / 海馬歯状回 / DREADD / ドーパミン / 低強度運動 / DREADDシステム / 意欲 / fMRI / 認知機能 / 運動 / DR53 group / Phylogenic tree / Haplotype / DRB1 gene / DRB1遺伝子 / ハプロタイプ / chromosome 9 / pooling / ΔAIP / chromosome 1 / genome scan / 染色体異常 / AIP / スクリーニング / 関連研究 / D9S15 / 9番染色体 / プーリング / デルタAIP / 1番染色体 / neurodevelop mental disorder / Seasonality of birth / Chromosome 6p / Genetics / DR4 / DR・1 / 慢性関節リューマチ / 感染 / 出生季節性 / 6番染色体短腕 / 出生季節 / 6番染色体短腕(6P) / 遺伝 / neurotrophin-3 (Nt-3) / brain-derived neurotrophic factor (BDNF) / polymorphism / mutation / ciliary neurotrophic factor (CNTF) / neurodevelopmental / 変異 / CNTF / ニューロトロフィン3 / 脳由来成長因子 / 多型 / 遺伝子変異 / 毛様体神経栄養因子 / 神経発達 / オリゴデンドロサイト / PMP22 / 家族性圧脆弱性ニューロパチー / 遺伝子 / 脳・神経 / 脳神経疾患 / SNPs(一塩基多型) / 一塩基多型(SNP) / early growth response / セロトニン神経 / ADHD / 疾患モデル / 遺伝子改変マウス / 精神疾患・障害 / 神経ペプチドPACAP / 臨床遺伝学 / 薬理学 / SNPsチップ / 中間表現型 / 染色体構造異常スクリーニング / 表現型不一致一卵性双生児 / 疾患感受性遺伝子 / 候補遺伝子 / 微小染色体構造異常 / 遺伝子発現差異解析 / 一卵性双生児不一致例 / 500K SNPsチップ / ゲノムワイドスキャン / 相関解析 / 双生児 / ゲノムスキャン(GWAS) / 病因遺伝子 / パニック障害 / 900k array / twin / twin NIRS / CGH array / CNVs / SNPs / GWAS / risk genes / panic disorder / ゲノムDNA / エピジェネティク / DNAメチレーション / 関連解析 / DNAメチル化 / エピジェネティクス / 3塩基繰り返し / ApoER2 / CNR / リーリン / WAIS-R / Event Related Potential事象関連電位 / Role Ploy Test / Cognitive Function認知機能 / Schigophrenia精神分裂病 / Social Skills Training生活技能訓練 Less
  • Research Projects

    (23 results)
  • Research Products

    (67 results)
  • Co-Researchers

    (63 People)
  •  Creation and clinical application of 3D brain barrier chips using human iPS cells

    • Principal Investigator
      出口 芳春
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Teikyo University
  •  [1-13C]Trpと[1-13C]5-HTPの合成とうつ病の客観的診断法の開発

    • Principal Investigator
      梶原 康宏
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 33020:Synthetic organic chemistry-related
    • Research Institution
      Yokohama College of Pharmacy
  •  Research on molecular and brain basis for sensorimotor gating dysfunction

    • Principal Investigator
      Matsuo Junko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Study of drug discovery and biomarker for depression based on glial antidepressant receptor (LPA1)

    • Principal Investigator
      Takebayashi Minoru
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Kumamoto University
      Department of Clinical Research, National Hospital Organization Kure Medical Center
  •  Study on the clinical use of (13)C-tryptophan breath test in depressive disorderPrincipal Investigator

    • Principal Investigator
      Kunugi Hiroshi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Psychiatric science
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Translational study on exercise program for promoting vitality of body and mind: unravel the mechanism of enhancing motivation and cognitive function in brain.

    • Principal Investigator
      SOYA Hideaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Sports science
    • Research Institution
      University of Tsukuba
  •  Development of biomarkers for functional psychoses based on multiple omics analysesPrincipal Investigator

    • Principal Investigator
      Kunugi Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Psychiatric science
    • Research Institution
      National Center of Neurology and Psychiatry
  •  The application of stable isotope breath test and biopterin administration to the evaluation and treatment of psychiatric disordersPrincipal Investigator

    • Principal Investigator
      KUNUGI Hiroshi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Psychiatric science
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Role of neurotrophin receptor p75 in psychiatric diseasesPrincipal Investigator

    • Principal Investigator
      KUNUGI Hiroshi
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Search and functional analysis for candidate gene of schizophrenia by CGH array method.

    • Principal Investigator
      OZEKI Yuji
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Dokkyo Medical University
      National Center of Neurology and Psychiatry
  •  Molecular genetic study on the pathophysiology of psychiatric disorders based on the role of PACAP

    • Principal Investigator
      SHINTANI Norihito, 橋本 均
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Osaka University
  •  A Search for Risk Genes of Psychiatric Disorders

    • Principal Investigator
      OKAZAKI Yuji
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
      Mie University
  •  プレパルス抑制検査を用いた統合失調症の病態の解明と診断法の開発Principal Investigator

    • Principal Investigator
      功刀 浩
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Psychiatric science
    • Research Institution
      National Center of Neurology and Psychiatry
  •  メチル化によるエピジェネティクなゲノム変化と統合失調症との関連解析

    • Principal Investigator
      HOHJOH Hirohiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Psychiatric science
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Phylogenetic analyses of the HLA-DRB1 gene based on the DR haplotypes

    • Principal Investigator
      HOHJOH Hirohiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      遺伝
    • Research Institution
      National Center of Neurology and Psychiatry (NCNP)
  •  Polymorphism screening and association analysis of neurotrophic factor genes in neuropsychiatric diseasesPrincipal Investigator

    • Principal Investigator
      KUNUGI Hiroshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      National Center of Neurology and Psychiatry
      Teikyo University
  •  精神分裂病関連遺伝子の解明

    • Principal Investigator
      NANKO Shinichiro
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Teikyo University
  •  Genome Scan of Candidate Region of Schizophrenia using DNA Pooling Method

    • Principal Investigator
      NANKO Shinichiro
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Psychiatric science
    • Research Institution
      Teikyo University
  •  Role of neurotrophic factors in the susceptibility to schizophrenia and its brain abnormalitiesPrincipal Investigator

    • Principal Investigator
      KUNUGI Hiroshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Teikyo University
  •  Relationships between polymorphisms of genes encoding neurotrophic factors and neurodevelopment in schizophreniaPrincipal Investigator

    • Principal Investigator
      KUNUGI Hiroshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      TEIKYO UNIVERSITY
  •  Study of genetic markers on the short arm of the chromosome 6 (6p) in schizophrenia : analysis of schizophrenia susceptibility gene

    • Principal Investigator
      SASAKI Tsukasa
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      The University of Tokyo
      Teikyo University
  •  Molecular genetics study of schizophrenia based on neurodevelopmental hypothesis

    • Principal Investigator
      NANKO Shinichiro
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Psychiatric science
    • Research Institution
      Teikyo University
  •  社会生活技能訓練による精神分裂病患者の再発減少効果の研究-服薬管理技能や再発前駆症状への対処技能の向上を治療標的として.

    • Principal Investigator
      池淵 恵美
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Teikyo University

All 2021 2020 2019 2018 2016 2015 2014 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book Patent Other

  • [Book] 非侵襲的検体検査の最前線―唾液検査・呼気検査を中心にー (槻木恵一監修)2015

    • Author(s)
      寺石俊也、功刀浩
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-15K15439
  • [Book] うつ病のBDNF仮説.最新うつ病のすべて2010

    • Author(s)
      功刀浩
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-20390318
  • [Book] 別冊・医学のあゆみ(うつ病のBDNF仮説.最新うつ病のすべて)(樋口輝彦編)2010

    • Author(s)
      功刀浩
    • Publisher
      医歯薬出版,東京
    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] Reduced serum and cerebrospinal fluid levels of autotaxin in major depressive disorder.2019

    • Author(s)
      Itagaki K,Takebayashi M,Abe H,Shibasaki C,Kajitani N,Okada-Tsuchioka M,Hattori K,Yoshida S,Kunugi H,Yamawaki S.
    • Journal Title

      International Journal of Neuropsychopharmacology

      Volume: 22 Pages: 261-269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02756
  • [Journal Article] キヌレニン経路2016

    • Author(s)
      寺石俊也、功刀浩
    • Journal Title

      分子精神医学

      Volume: 16 Pages: 47-49

    • Data Source
      KAKENHI-PROJECT-15K15439
  • [Journal Article] Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase: New Targets for Future Antidepressants.2015

    • Author(s)
      Ogawa S, Kunugi H
    • Journal Title

      Curr Neuropharmacol

      Volume: 13 Issue: 6 Pages: 760-775

    • DOI

      10.2174/1570159x13666150612225212

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Journal Article] Increased cerebrospinal fluid fibrinogen in major depressive disorder.2015

    • Author(s)
      Hattori K, Ota M, Sasayama D, Yoshida S, Matsumura R, Miyakawa T, Yokota Y, Yamaguchi S, Noda T, Teraishi T, Hori H, Higuchi T, Kohsaka S, Goto Y, Kunugi H.
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 11412-11412

    • DOI

      10.1038/srep11412

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Journal Article] うつ病を生物学的に理解する.2015

    • Author(s)
      功刀 浩
    • Journal Title

      医学と薬学

      Volume: 72 Pages: 1841-1849

    • Data Source
      KAKENHI-PROJECT-25253075
  • [Journal Article] うつ病の病態仮説と分子マーカー2015

    • Author(s)
      功刀 浩
    • Journal Title

      精神科診断学

      Volume: 8 Pages: 16-20

    • Data Source
      KAKENHI-PROJECT-25253075
  • [Journal Article] ^<13>C-phenylalanine breath test detects altered phenylalanine kinetics in schizophrenia patients2012

    • Author(s)
      Toshiya Teraishi, Yuji Ozeki, Hiroaki Hori, Daimei Sasayama, Shuichi Chiba, Noriko Yamamoto, Haruko Tanaka, Yoshimi Iijima, Junko Matsuo, Yumiko Kawamoto, Yukiko Kinoshita, Kotaro Hattori, Miho ota, Masahiro Kajiwara, Sumio Terada, Teruhiko Higuchi, Hiroshi Kunugi
    • Journal Title

      Translational psychiatry

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659215
  • [Journal Article] Possible association of the semaphorin 3D gene (SEMA3D) with schizophrenia.2011

    • Author(s)
      Fujii T, Uchiyama H, Yamamoto N, Hori H, Tatsumi M, Ishikawa M, Arima K, Higuchi T, Kunugi H.
    • Journal Title

      J Psychiatr Res. 45(1)

      Pages: 47-53

    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression.2010

    • Author(s)
      Kunugi H, Hori H, Adachi N, Numakawa T.
    • Journal Title

      Psychiatry Clin Neurosci. 64(5)

      Pages: 447-459

    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression.2010

    • Author(s)
      Kunugi H, et al.
    • Journal Title

      Psychiatry Clin Neurosci.

      Volume: 64 Pages: 447-459

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] Sexually dimorphic effect of the Val66Met polymorphism of BDNF on susceptibility to Alzheimer's disease : New data and meta-analysis.2010

    • Author(s)
      Fukumoto N, Fujii T, Combarros O, Kamboh MI, Tsai SJ, Matsushita S, Nacmias B, Comings DE, Arboleda H, Ingelsson M, Hyman BT, Akatsu H, Grupe A, Nishimura AL, Zatz M, Mattila KM, Rinne J, Goto Y, Asada T, Nakamura S, Kunugi H.
    • Journal Title

      Am J Med Genet B Neuropsychiatr Genet. 153B(1)

      Pages: 235-242

    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] Possible interaction between glucocorticoid and BDNF function2010

    • Author(s)
      Numakawa T, Kunugi H.
    • Journal Title

      生化学

      Volume: 82 Pages: 419-422

    • NAID

      10026425972

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] p75NTR as a therapeutic target for neuropsychiatric diseases.2009

    • Author(s)
      Fujii T, Kunugi H.
    • Journal Title

      Curr Mol Pharmacol. 2(1)

      Pages: 70-76

    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-gamma signaling for glutamate release via a glutamate transporter.2009

    • Author(s)
      Numakawa T, Kumamaru E, Adachi N, Yagasaki Y, Izumi A, Kunugi H.
    • Journal Title

      Proc Natl Acad Sci U S A. 106(2)

      Pages: 647-652

    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] p75NTR as a therapeutic target for neuropsychiatric diseases2009

    • Author(s)
      Fujii T, Kunugi H.
    • Journal Title

      Curr Mol Pharmacol

      Volume: 2(1) Pages: 70-6

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20021447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] BDNF is not associated with schizophrenia : data from a Japanese population study and meta-analysis.2009

    • Author(s)
      Kawashima K, Ikeda M, Kishi T, Kitajima T, Yamanouchi Y, Kinoshita Y, Okochi T, Aleksic B, Tomita M, Okada T, Kunugi H, Inada T, Ozaki N, Iwata N.
    • Journal Title

      Schizophr Res. 112(1-3)

      Pages: 72-79

    • Data Source
      KAKENHI-PROJECT-20390318
  • [Journal Article] A case of schizophrenia with chromosomal microdeletion of 17p11.2 containing a myelin-related gene PMP222008

    • Author(s)
      Yuji Ozeki, Takeshi Mizuguchi, Naotsugu Hirabayashi, Masafumi Ogawa, Naomi Ohmura, Miyuki Moriuchi, Naoki Haradae, Naomichi Matsumoto, Hiroshi Kunugi
    • Journal Title

      The Open Psychiatry Joumal 2

      Pages: 1-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591392
  • [Journal Article] A case of schizophrenia with chromosomal microdeletion of 17p11.2 containing a myelin-related gene PMP22.2008

    • Author(s)
      Yuji Ozeki, Takeshi Mizuguchi, Naotsugu Hirabayashi, Masafumi Ogawa, Naomi Ohmura,Miyuki Moriuchi, Naoki Haradae, Naomichi Matsumoto, Hiroshi Kunugi
    • Journal Title

      The Open Psychiatry Journal 2

      Pages: 1-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591392
  • [Journal Article] Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia2007

    • Author(s)
      Hashimoto R, Hashimoto H, Shintani N, Kunugi H, Baba A, 計9名
    • Journal Title

      Mol.Psychiatry 12

      Pages: 1026-1032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390025
  • [Journal Article] Psychostimulant-induced attenuation of hyperactivity and prepulse inhibition deficits in Adcyapl-deficient mice2006

    • Author(s)
      Tanaka K, Shintani N, Hashimoto H, Hashimoto R, Kunugi H, Baba A
    • Journal Title

      J.Neurosci. 26

      Pages: 5091-5097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390025
  • [Patent] miRNAを用した精神疾患判定マーカー2015

    • Inventor(s)
      服部功太郎、功刀浩、後藤雄一、高坂新一
    • Industrial Property Rights Holder
      独)国立精神・神経医療研究センター
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-008710
    • Filing Date
      2015-01-20
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Patent] 精神疾患判定マーカー2014

    • Inventor(s)
      服部功太郎、功刀浩、後藤雄一、髙坂新一
    • Industrial Property Rights Holder
      (独)国立精神・神経医療研究センター
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-102090
    • Filing Date
      2014-05-16
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Presentation] 気分障害患者の脳脊髄液中のフィブリノーゲン:健常者との比較および症状・服薬との関連2021

    • Author(s)
      松尾淳子、服部 功太郎、秀瀬真輔、篠山 大明、横田 悠季、松村 亮、石田一希、 太田深秀、堀弘明、蓬田幸人、功刀浩
    • Organizer
      日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-19K08059
  • [Presentation] 気分障害患者の脳脊髄液中のフィブリノーゲン:健常者との比較および症状・服薬との関連2021

    • Author(s)
      松尾 淳子、服部 功太郎、秀瀬 真輔、篠山 大明、横田 悠季、松村 亮、石田 一希、太田 深秀、堀 弘明、蓬田 幸人、功刀 浩
    • Organizer
      日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-19K08059
  • [Presentation] 健常成人における感覚ゲーティングと認知機能2021

    • Author(s)
      松尾淳子、 石田一希、太田深秀、秀瀬真輔、堀弘明、蓬田幸人、功刀浩
    • Organizer
      日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-19K08059
  • [Presentation] 統合失調症の脳脊髄液中のフィブリノーゲン:健常者との比較および症状・服薬との関連2021

    • Author(s)
      松尾淳子、服部 功太郎、秀瀬真輔、篠山 大明、横田 悠季、松村 亮、石田一希、 太田深秀、堀弘明、蓬田幸人、功刀浩
    • Organizer
      日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-19K08059
  • [Presentation] 双極性障害患者の握力と認知機能2021

    • Author(s)
      松尾淳子、 石田一希、太田深秀、秀瀬真輔、堀弘明、蓬田幸人、功刀浩
    • Organizer
      日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-19K08059
  • [Presentation] うつ病患者の感覚ゲーティングと脳脊髄液中の炎症性サイトカインとの関連:予備的検討2021

    • Author(s)
      松尾 淳子、秀瀬 真輔、服部 功太郎、篠山 大明、横田 悠季、松村 亮、石田 一希、太田 深秀、堀 弘明、蓬田 幸人、功刀 浩
    • Organizer
      日本神経科学会
    • Data Source
      KAKENHI-PROJECT-19K08059
  • [Presentation] 統合失調症の脳脊髄液中のフィブリノーゲン:健常者との比較および症状・服薬との関連2021

    • Author(s)
      松尾 淳子、服部 功太郎、秀瀬 真輔、篠山 大明、横田 悠季、松村 亮、石田 一希、太田 深秀、堀 弘明、蓬田 幸人、功刀 浩
    • Organizer
      日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-19K08059
  • [Presentation] 健常成人における感覚ゲーティングと認知機能2021

    • Author(s)
      松尾淳子、石田一希、太田深秀、秀瀬真輔、堀弘明、蓬田幸人、功刀浩
    • Organizer
      日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-19K08059
  • [Presentation] Association between sensorimotor gating and cerebrospinal fluid monoamine metabolite and fibrinogen levels: A preliminary study2020

    • Author(s)
      Junko Matsuo, Kotaro Hattori, Shinsuke Hidese, Miho Ota, Yukihito Yomogida, Ikki Ishida, Moeko Hiraishi, Shintaro Ogawa, Hiroshi Kunugi
    • Organizer
      The Japan Neuroscience Society
    • Data Source
      KAKENHI-PROJECT-19K08059
  • [Presentation] Abnormality in metabolism of docosahexaenoic acid-lysophosphatidic acid(DHA-LPA) in major depressive disorder and schizophrenia2019

    • Author(s)
      Omori W,Kano K,Hattori K,Kajitani N,Itagaki K,Okada-Tsuchioka M,Abe H,Machino A,Inoue A,Kunugi H,Aoki J,Takebayashi M.
    • Organizer
      Neuroscience 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02756
  • [Presentation] Altered cerebrospinal fluid levels of matrix metalloproteinases in mood disorders and schizophrenia.2018

    • Author(s)
      Omori W,Hattori K,Okada-Tsuchioka M,Itagaki K,Kajitani N,Abe H,Kunugi H,Takebayashi M
    • Organizer
      Neuroscience 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02756
  • [Presentation] 13C-トリプトファン呼気検査による、うつ病のキヌレニン仮説についての検討.2016

    • Author(s)
      寺石俊也, 堀弘明, 篠山大明, 松尾淳子, 小川眞太朗, 太田深秀, 服部功太郎, 梶原正宏, 功刀浩
    • Organizer
      第38回日本生物学的精神医学会 第59回日本神経化学会大会合同年会,
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-15K15439
  • [Presentation] Collection of cerebrospinal fluid bioresource and multiple omics approaches to psychiatric disorders. Symposium "Progress in cerebral fluid markers in neuropsychiatric diseases2015

    • Author(s)
      Hattori K, Yoshida S, Goto Y, Kunugi H
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2015-07-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Presentation] Increased cerebrospinal fluid fibrinogen delineates a subgroup of major depressive disorder.2015

    • Author(s)
      Hattori K, Ota M, Sasayama D, Yoshida S, Noda T, Teraishi T, Hori H, Kunugi H
    • Organizer
      World Psychiatric Association Regional Congress, Osaka, Japan
    • Place of Presentation
      Osaka 大阪国際会議場
    • Year and Date
      2015-06-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Presentation] うつ病を類型化する生化学的マーカー(教育講演)2015

    • Author(s)
      功刀 浩
    • Organizer
      第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
    • Place of Presentation
      東京 (タワーホール舟堀)
    • Year and Date
      2015-09-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Presentation] Reduced cerebrospinal fluid ethanolamine concentration in major depressive disorder.2015

    • Author(s)
      Ogawa S, Hattori K, Sasayama D, Yuki Yokota, Matsumura R, Matsuo J, Ota M, Hori H, Teraishi T, Yoshida S, Noda T, Ohashi Y, Sato H, Higuchi T, Motohashi N, Kunugi H
    • Organizer
      Asian Congress of Nutrition
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2015-05-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Presentation] 服薬していない外来うつ病患者における末梢血遺伝子発現プロファイル:網羅的遺伝子発現と候補遺伝子発現の統合的解析.2015

    • Author(s)
      堀 弘明, 篠山大明, 寺石俊也, 山本宜子, 中村誠二, 太田深秀, 服部功太郎, 金 吉晴, 樋口輝彦, 功刀 浩
    • Organizer
      第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
    • Place of Presentation
      東京(タワーホール舟堀)
    • Year and Date
      2015-09-25
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Presentation] グルココルチコイドと神経栄養因子を鍵分子とした精神疾患研究2010

    • Author(s)
      功刀浩
    • Organizer
      第2回生物学・化学・情報科学融合のための戦略的先進理工学研究基盤の形成(FBT)・超専攻型融合テーマスタディクラスター教育(TSC-PBL)ジョイントシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-01-23
    • Data Source
      KAKENHI-PROJECT-20390318
  • [Presentation] 食事・栄養による脳由来神経栄養因子(BDNF)の発現調節とメンタルヘルス2010

    • Author(s)
      功刀浩
    • Organizer
      第13回日本病態栄養学会年次学術集会
    • Place of Presentation
      グランドプリンスホテル京都
    • Year and Date
      2010-01-10
    • Data Source
      KAKENHI-PROJECT-20390318
  • [Presentation] Risk Genes for Panic Disorder: a GWAS Study.2008

    • Author(s)
      Tanii H, Sasaki T, Otowa T, Kato T, Yoshikawa T, Arinami T, Kunugi H, Someya T, Matumoto N, Kaiya H, Okazaki Y
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山市
    • Data Source
      KAKENHI-PROJECT-17019029
  • [Presentation] Chromosomal microdeletion of shicozphrenia2008

    • Author(s)
      Yuji Ozeki, Takeshi Mizuguchi, Naotsugu Hirabayashi, Tomoko Shizuno, Naomi Ohmura, Miyuki Moriuchi, Naoki Harada, Hiroaki Hori, Kunimasa Arima, Osamu Saitoh, Naomichi Matsumoto, Hiroshi Kunugi
    • Organizer
      Microdeletion screening and association study of PMP22 gene
    • Place of Presentation
      New York, USA
    • Year and Date
      2008-10-09
    • Data Source
      KAKENHI-PROJECT-19591392
  • [Presentation] Altered expression of BDNF gene and vulnerability to stress in Schizophrenia.2008

    • Author(s)
      Kunugi H
    • Organizer
      XXVI CINP Congress.
    • Place of Presentation
      Munich, Germany.
    • Year and Date
      2008-07-16
    • Data Source
      KAKENHI-PROJECT-20390318
  • [Presentation] Altered expression of BDNF gene and vulnerability to stress in Schizophrenia2008

    • Author(s)
      Kunugi H
    • Organizer
      XXVI CINP Congress
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2008-07-16
    • Data Source
      KAKENHI-PROJECT-20390318
  • [Presentation] Risk Genes for Panic Disorder : a GWAS Study2008

    • Author(s)
      Tanii H, Sasaki T, Otowa T, Kato T, Yoshikawa T, Arinami T, Kunugi H, Someya T, Matumoto N, Kaiya H, Okazaki Y
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山市
    • Data Source
      KAKENHI-PROJECT-17019029
  • [Presentation] うつ病の病態仮説と分子マーカー

    • Author(s)
      功刀浩
    • Organizer
      第34回日本精神科・診断学会
    • Place of Presentation
      愛媛県松山、大和屋本店
    • Year and Date
      2014-11-13 – 2014-11-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Presentation] うつ病の診断マーカー

    • Author(s)
      功刀浩
    • Organizer
      第36回 日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Presentation] The change of cocaine- and amphetamine-regulated transcript (CART) peptide levels in human cerebrospinal fluid (hCSF) of major depressive disorder (MDD) and the role of CART to modulate basal anxiety-related behavoiors in rats.

    • Author(s)
      Yoon HS, Hattori K, Sasayama D, Kunugi H
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Washington Convention Center, Washington, D.C. USA
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-25253075
  • [Presentation] 脳脊髄液fibrinogen上昇は大うつ病性障害の亜型を反映している

    • Author(s)
      服部功太郎、篠山大明、太田深秀、吉田寿美子、横田悠季、松村亮、宮川友子、野田隆正、功刀浩
    • Organizer
      第36回日本生物学的精神医学会第57回日本神経化学会大会
    • Place of Presentation
      奈良県文化会館・奈良県新公会堂
    • Year and Date
      2014-09-29 – 2014-10-01
    • Data Source
      KAKENHI-PROJECT-25253075
  • []

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  • 1.  NANKO Shinichiro (60101127)
    # of Collaborated Projects: 7 results
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  • 2.  LEE Kyu-Bak (40307202)
    # of Collaborated Projects: 3 results
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  • 3.  HOHJOH Hirohiko (60238722)
    # of Collaborated Projects: 2 results
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  • 4.  SASAKI Tsukasa (50235256)
    # of Collaborated Projects: 2 results
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  • 5.  SHINTANI Norihito (10335367)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  HATTORI Kotaro (50415569)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 7.  HIROSE Tetsuya (10101742)
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  • 8.  TOKUNAGA Katsushi (40163977)
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  • 9.  OKAZAKI Yuji (40010318)
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  • 10.  BABA Akemichi (70107100)
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  • 11.  AGO Yukio (50403027)
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  • 12.  HASHIMOTO Ryota (10370983)
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  • 13.  TOHYAMA Masaya (40028593)
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  • 14.  TAKEDA Masatoshi (00179649)
    # of Collaborated Projects: 1 results
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  • 15.  OZEKI Yuji (90303768)
    # of Collaborated Projects: 1 results
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  • 16.  NUMAKAWA Tadahiro (40425690)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 17.  FUJII Takashi (10450610)
    # of Collaborated Projects: 1 results
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  • 18.  SASAYAMA Daimei (90447764)
    # of Collaborated Projects: 1 results
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  • 19.  SUZUKI Hidetoshi (80328062)
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  • 20.  ISHIDA Takafumi (20184533)
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  • 21.  SOYA Hideaki (50221346)
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  • 22.  Takebayashi Minoru (60304440)
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  • 31.  吉川 武男 (30249958)
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  • 32.  有波 忠雄 (10212648)
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    # of Collaborated Projects: 1 results
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  • 40.  井上 飛鳥 (50525813)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 41.  太田 深秀 (00582785)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 42.  秀瀬 真輔 (50832763)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 43.  梶原 康宏 (50460283)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  庄司 満 (30339139)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  出口 芳春 (40254255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  萩原 将也 (00705056)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  久保 義行 (20377427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  川端 健二 (50356234)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  黒澤 俊樹 (90839466)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  TERAISHI Toshiya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 51.  貝谷 久宣
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  井上 顕
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  西村 幸香
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  西田 淳志
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  梅景 正
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  栃木 衛
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  音羽 健司
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  河村 代志也
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  今村 明
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  垣内 千尋
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 61.  石渡 みずほ
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 62.  穐吉 条太郎
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 63.  清水 栄司
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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