SASAJIMA Toshio 笹嶋寿郎

… Alternative Names

笹嶋寿郎ササジマトシオ

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Researcher Number	40235289
Other IDs
Affiliation (based on the past Project Information) *help	2012: 秋田大学, 医学(系)研究科(研究院), 准教授 2008 – 2012: Akita University, 大学院・医学系研究科, 准教授 2007 – 2008: Akita University, School of Medicine, Associate Professor 2005 – 2006: Akita Univ., Sch.of Med., Associate Prof., 医学部, 助教授 1998 – 2004: 秋田大学, 医学部, 講師 1997: 秋田大学, 医学部, 助手 1993 – 1994: 秋田大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Cerebral neurosurgery Except Principal Investigator Cerebral neurosurgery / Cerebral neurosurgery
Keywords	Principal Investigator 増殖能 / ^<99m>Tc-MIBI / 悪性脳腫瘍 / MTT assay / 脳腫瘍 / drug resistance / 薬剤耐性 / アミノ酸代謝 / 糖代謝 / オートラジオグラフィー … More / amino acid metabolism / tumor proliferation / vincristine / MDR1 inhibitors / malignant brain tumors / 三重標識組織放射能測定法 / ^3H-ビンクリスチン / 移植脳腫瘍 / ビンクリスチン / 耐性克服薬 / MDR1mRNA expression / malignant tumor / MDR1mRNA発見 / Tc^<99m>-MIBI / MDR1mRNA発現 / 腫瘍増殖能 / メチオニン / 抗血管新生療法 / インターフェロン / 人工アミノ酸 / ベバシズマブ / インターフェロンβ / テモゾロミド / 人工アミノ酸トレーサ / 腫瘍イメージング / 腫瘍幹細胞 / 低酸素誘導因子 / 低酸素細胞 / 脳血流量 / 腫瘍壊死因子動注療法 / ^<14>C-メチオニン / シスプラチン … More Except Principal Investigator 脳腫瘍 / brain tumor / 脳磁図 / functional PET / functional MRI / magnetoencephalography / fMRI / 言語機能マッピング / 脳神経外科 / ultrasound / maanetoencephalography / brain metabolism / brain function / Neuronavigation / Neurosurgery / 脳神経疾患 / 超音波 / 脳代謝 / 脳機能 / 手術支援装置 / surgical navigation / functional brain mapping / 手術ナビゲーション / f-MRI / f-PET / language area / functional mapping / 言語タスク / 言語機能 / PET / chemotherapeutic agent / glucose metabolism / amino acid metabolism / tumo proliferation / vascular endothelial growth factor / angiogenesis inhibitor / malignant brain tumor / 低酸素細胞 / 抗腫瘍薬 / 糖代謝 / アミノ酸代謝 / 増殖能 / 血管内皮増殖因子 / 抗血管新生療法 / 手術機器学 / 手術支援システム / 手術支援 / 手術器機学 Less

Experimental studies of synthesized amino acid analog anti-FACBC as imaging biomarker to monitor treatment response of glioblatomas to temozolomide therapy with interferon-. and bevacizumabPrincipal Investigator
- Principal Investigator
  
  SASAJIMA Toshio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
Development of a novel multi-modal surgical navigation system with the integration of three-dimensional cerebrovascular imaging data.
- Principal Investigator
  
  MIZOI Kazuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
Experimental studies of CD133(+) glioblastoma stem cells under normoxic and hypoxic conditionsPrincipal Investigator
- Principal Investigator
  
  SASAJIMA Toshio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
Development of the multimodal neuronavigation system integrating structural and functional information in combination with intra-operative ultrasound imaging.
- Principal Investigator
  
  MIZOI Kazuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
Experimental studies on potentiation of antitumor agent by the second generation MDR1 inhibitors in malignant brain tumors : Monitoring multidrug resistance using ^<99m>Tc-MIBIPrincipal Investigator
- Principal Investigator
  
  SASAJIMA Toshio
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
Establishment of cortical mapping of speech areas by multimodal functional image fusions using neuronavigation system
- Principal Investigator
  
  MIZOI Kazuo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
Integrated analysis of language area using MEG, functional MRI and PET. -Clinical application to brain tumor surgery-
- Principal Investigator
  
  MIZOI Kazuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
Experimental studies of antitumor effects ofangiogenesis inhibitor TNP-470 with a chemotherapeutic agent on a malignant brain tumor.
- Principal Investigator
  
  MIZOI Kazuo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
Monitoring the functional expression of multidrug resistance gene (MDR1) and study on potentiation of antitumor agent by MDR1 inhibitors in brain tumors.Principal Investigator
- Principal Investigator
  
  SASAJIMA Toshio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
脳腫瘍における低酸素細胞の増殖能と糖およびアミノ酸代謝に関する研究Principal Investigator
- Principal Investigator
  
  笹嶋寿郎
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
脳腫瘍における腫瘍壊死因子動注療法による循環代謝の変動と治療効果に関する研究Principal Investigator
- Principal Investigator
  
  笹嶋寿郎
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
脳腫瘍におけるアミノ酸代謝とシスプラチンの作用機序に関する研究Principal Investigator
- Principal Investigator
  
  笹嶋寿郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University

All 2010 2008 2006 2004

All Journal Article Presentation Book

[Book] 脳神経検査のグノーティ・セアウトンpart1 MRI編, 小川彰(編集)2010
- Author(s)
  笹嶋寿郎, 溝井和夫
- Publisher
  シナジー,東京
- Data Source
  KAKENHI-PROJECT-20591703
[Book] 脳神経検査のグノーティ・セアウトン(part1 MRI編、小川彰(編集))2010
- Author(s)
  笹嶋寿郎、溝井和夫
- Publisher
  シナジー、東京
- Data Source
  KAKENHI-PROJECT-20591703
[Book] Oligodendroglial tumorsに対するmultimodal navigationを用いた外科治療(甲村英二(編))(脳腫瘍の外科-基本と挑戦-)2008
- Author(s)
  笹嶋寿郎、東山巨樹、高橋和孝、太田徹、柴田憲一、茨木正信、木下俊文、溝井和夫
- Publisher
  メディカ出版、大阪
- Data Source
  KAKENHI-PROJECT-20591703
[Journal Article] Association of stem cell marker CD133 expression with dissemination of glioblastomas.2010
- Author(s)
  Sato A, Sasajima T, Beppu T, Ogawa A, Mizoi K, Tominaga T Kitanaka C, Kayama T
- Journal Title
  
  Neurosurg Rev
  
  Volume: 33 Pages: 175-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591703
[Journal Article] Skull base malignant lymphomaの1例-FDG・PET診断の重要性-2010
- Author(s)
  島田直也, 笹嶋寿郎, 高橋和孝, 高橋佑介, 柴田憲一, 柳澤俊晴, 溝井和夫
- Journal Title
  
  東北脳SPECT研究会講演集
  
  Volume: 19 Pages: 9-13
- Data Source
  KAKENHI-PROJECT-20591703
[Journal Article] Skull base malignant lymphomaの1例-FDG-PET診断の重要性-2010
- Author(s)
  島田直也、笹嶋寿郎、高橋和孝、高橋佑介、柴田憲一、柳澤俊晴、溝井和夫
- Journal Title
  
  東北脳SPECT研究会講演集 19巻
  
  Pages: 9-13
- Data Source
  KAKENHI-PROJECT-20591703
[Journal Article] Axonal viability of corticospinal tracts evaluated by diffusion tensor imaging relates to reversible motor function and crossed cerebellar diaschisis.2008
- Author(s)
  Kawashima A, Sasajima T, Shimosegawa E, Takahashi M, Suzuki A, Yasui N, Mizoi K
- Journal Title
  
  Akita J Med 34巻
  
  Pages: 223-236
- NAID
  110006968025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591703
[Journal Article] ^<123> I-metaiodobenzylguanidnine single-photon emission computerized tomography in brain tumors-a preliminary study2006
- Author(s)
  Sasajima T, et. al.
- Journal Title
  
  Journal of Neuro-Oncology 77
  
  Pages: 185-191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591573
[Journal Article] ^<123>I-metaiodobenzylguanidnine single-photon emission computerized tomography in brain tumors-a preliminary study.2006
- Author(s)
  Sasajima T, et al.
- Journal Title
  
  Journal of Neuro-Oncology 77
  
  Pages: 185-191
- Data Source
  KAKENHI-PROJECT-18591573
[Journal Article] ^<123>I-metaiodobenzylguanidnine single-photon emission computerized tomography in brain tumors - a preliminary study2006
- Author(s)
  Sasajima, T, et. al.
- Journal Title
  
  Journal of Neuro-Oncology 77
  
  Pages: 185-191
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591573
[Journal Article] Proliferation-dependent changes in amino acid transport and glucose metabolism in cell lines.2004
- Author(s)
  Sasajima T, et al.
- Journal Title
  
  Eur J Nucl Mol Imageing 31
  
  Pages: 1244-1256
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591427
[Presentation] 脳動脈瘤直達術における動注蛍光血管撮影の有用性-浅側頭動脈経由法2010
- Author(s)
  柳澤俊晴、柴田憲一、島田直也、高橋和孝、笹嶋寿郎、溝井和夫
- Organizer
  第69回日本脳神経外科学会総会
- Place of Presentation
  福岡
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-20591703
[Presentation] 破裂脳動脈手術における術中DSAの安全性と有用性2008
- Author(s)
  内藤雄一郎、柳澤俊晴、木内博之、笹嶋寿郎、太田徹、鈴木明、高橋和孝、東山巨樹,菅原卓、溝井和夫
- Organizer
  第67回日本脳神経外科学会総会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20591703
[Presentation] 脳磁図を用いた言語機能局在同定法の臨床応用2008
- Author(s)
  太田徹、柴田憲一、東山巨樹、笹嶋寿郎、高橋和孝、柳澤俊晴、鈴木明、菅原卓、溝井和夫
- Organizer
  第67回日本脳神経外科学会総会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20591703
[Presentation] 言語野近傍intrinsic tumorsに対する集学的治療戦略2008
- Author(s)
  笹嶋寿郎、東山巨樹、高橋和孝、太田徹、鈴木明、茨木正信、木下俊文、溝井和夫
- Organizer
  第67回日本脳神経外科学会総会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20591703

1. MIZOI Kazuo (70157519)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results

SASAJIMA Toshio 笹嶋 寿郎

笹嶋 寿郎 ササジマ トシオ

Research Projects

Research Products

Co-Researchers

Experimental studies of synthesized amino acid analog anti-FACBC as imaging biomarker to monitor treatment response of glioblatomas to temozolomide therapy with interferon-. and bevacizumabPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel multi-modal surgical navigation system with the integration of three-dimensional cerebrovascular imaging data.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental studies of CD133(+) glioblastoma stem cells under normoxic and hypoxic conditionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the multimodal neuronavigation system integrating structural and functional information in combination with intra-operative ultrasound imaging.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental studies on potentiation of antitumor agent by the second generation MDR1 inhibitors in malignant brain tumors : Monitoring multidrug resistance using ^<99m>Tc-MIBIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of cortical mapping of speech areas by multimodal functional image fusions using neuronavigation system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Integrated analysis of language area using MEG, functional MRI and PET. -Clinical application to brain tumor surgery-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental studies of antitumor effects ofangiogenesis inhibitor TNP-470 with a chemotherapeutic agent on a malignant brain tumor.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Monitoring the functional expression of multidrug resistance gene (MDR1) and study on potentiation of antitumor agent by MDR1 inhibitors in brain tumors.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳腫瘍における低酸素細胞の増殖能と糖およびアミノ酸代謝に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳腫瘍における腫瘍壊死因子動注療法による循環代謝の変動と治療効果に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳腫瘍におけるアミノ酸代謝とシスプラチンの作用機序に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 脳神経検査のグノーティ・セアウトンpart1 MRI編, 小川彰(編集)2010

Author(s)

Publisher

SASAJIMA Toshio 笹嶋寿郎

笹嶋寿郎ササジマトシオ