Nagata Satoshi 永田諭志

… Alternative Names

NAGATA Satoshi 永田諭志

永田諭志ナガタサトシ

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Researcher Number	40246682
Other IDs
Affiliation (Current)	2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所創薬デザイン研究センター, プロジェクトリーダー
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所創薬デザイン研究センター, プロジェクトリーダー 2019 – 2020: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所創薬デザイン研究センター, プロジェクトリーダー 2017 – 2018: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所創薬デザイン研究センター, 主任研究員 1997 – 1999: 東京大学, 大学院・農学生命科学研究科, 講師 1994: 東京理科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / 応用微生物学・応用生物化学 / Virology Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / 応用微生物学・応用生物化学
Keywords	Principal Investigator モノクローナル抗体 / 抗体工学 / 免疫学 / アンタゴニスト抗体 / アゴニスト抗体 / TNFR2 / 制御性T細胞 / FCRL3 / 細胞内情法伝達 / モノクロナール抗体 … More / ホファチジルイノシトール / 細胞増殖 / 細胞分化 / 細胞内局在 / 競合法ELISA / ホスファチジルイノシトール3-キナーゼ / PIP_3 / 3′-リン酸化イノシトールリン脂質 / 融合ドメイン / エピトープ / 膜融合 / 膜糖タンパク質 / 水疱性口内炎ウイルス … More Except Principal Investigator MDSC / Treg / TNFR2 / ホスファチジルイノシトール / 細胞増殖 / 細胞分化 / バイオ医薬品 / 抗体 / 腫瘍免疫 / がん免疫療法 / APP3 / phospholipase / MAP kinase / polyphosphoinositides / adapter / differentiation / cell response / phosphatidylinositol kinase / phospholipids / 分化因子 / 増殖因子 / 細胞応答 / ホスファチジルイノシトール3キナーゼ / イノシトールリン脂質 / ホスホリパーゼ / MAPキナーゼ / イノシトールリン酸 / アダプター / 分化 / 組織応答 / ホシファテシジルイノシトールキナーゼ / リン脂質 / 情報伝達 / 核移行 Less

2型TNF受容体を介する免疫制御機構の解明とがん免疫療法への応用
- Principal Investigator
  
  角田慎一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kobe Gakuin University
Development of antibody design optimized for active targeting
- Principal Investigator
  
  鎌田春彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Study of TNFR2-APP3 signaling pathway and and its immuno-suppressive function
- Principal Investigator
  
  Tsunoda Shin-ichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kobe Gakuin University
Functional antibodies against membrane receptors expressed on regulatory T cells in correlation with immunosuppressive functionPrincipal Investigator
- Principal Investigator
  
  Nagata Satoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Studies on signal transduction in generation and development of cancers.
- Principal Investigator
  
  FUKUI Yasuhisa
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
細胞の分化・増殖における3'リン酸化イノシトールリン脂質の役割
- Principal Investigator
  
  FUKUI Yasuhisa
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
細胞の増殖・分化における3′-リン酸化イノシトールリン脂質の役割Principal Investigator
- Principal Investigator
  
  永田諭志
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
水疱性口内炎ウイルス膜糖タンパク質の細胞融合能に関わる抗原エピトープの同定Principal Investigator
- Principal Investigator
  
  永田諭志
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Virology
- Research Institution
  Tokyo University of Science

All 2019 2018

All Journal Article

[Journal Article] 高効率な臨床抗体の開発を目指して2019
- Author(s)
  鎌田春彦, 永田諭志, 近藤裕郷
- Journal Title
  
  臨床化学
  
  Volume: 48 Pages: 91-97
- Data Source
  KAKENHI-PROJECT-17K08300
[Journal Article] Anti-BCMA immunotoxins produce durable complete remissions in two mouse myeloma models2019
- Author(s)
  Shancer Zoe、Liu Xiu-fen、Nagata Satoshi、Zhou Qi、Bera Tapan K.、Pastan Ira
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 10 Pages: 4592-4598
- DOI
  10.1073/pnas.1821733116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08300
[Journal Article] The Differentiation in vitro of Human Tonsil B Cells With the Phenotypic and Functional Characteristics of T-bet+ Atypical Memory B Cells in Malaria2019
- Author(s)
  Abhijit A Ambegaonkar, Satoshi Nagata, Susan K Pierce, Haewon Sohn
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 10 Pages: 852-852
- DOI
  10.3389/fimmu.2019.00852
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08300
[Journal Article] Effect of allotypic variation of human IgG1 on the thermal stability of disulfide-linked knobs-into-holes mutants of the Fc for stable bispecific antibody design2019
- Author(s)
  Hiroki Akiba, Reiko Satoh, Satoshi Nagata, Kouhei Tsumoto
- Journal Title
  
  Antibody Therapeutics
  
  Volume: 2 Issue: 3 Pages: 65-69
- DOI
  10.1093/abt/tbz008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08300
[Journal Article] Clinical significance of MUC13 in pancreatic ductal adenocarcinoma2018
- Author(s)
  Khan Sheema、Zafar Nadeem、Khan Shabia S.、Setua Saini、Behrman Stephen W.、Stiles Zachary E.、Yallapu Murali M.、Sahay Peeyush、Ghimire Hemendra、Ise Tomoko、Nagata Satoshi、Wang Lei、Wan Jim Y.、Pradhan Prabhakar、Jaggi Meena、Chauhan Subhash C.
- Journal Title
  
  HPB
  
  Volume: 20 Issue: 6 Pages: 563-572
- DOI
  10.1016/j.hpb.2017.12.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08300, KAKENHI-PROJECT-16K07158
[Journal Article] Longitudinal autoantibody responses against tumor-associated antigens decrease in breast cancer patients according to treatment modality2018
- Author(s)
  Evans Rick L.、Pottala James V.、Nagata Satoshi、Egland Kristi A.
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Issue: 1 Pages: 119-119
- DOI
  10.1186/s12885-018-4022-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08300
[Journal Article] 標的に抗体が結合できる部位はいくつあるか?-効率よく新しい機能抗体を探索するためのエピトープ均質化抗体パネル2018
- Author(s)
  永田諭志、伊勢知子、鎌田春彦
- Journal Title
  
  実験医学
  
  Volume: 36 Pages: 1867-1874
- Data Source
  KAKENHI-PROJECT-17K08300
[Journal Article] Preclinical development of anti-BCMA immunotoxins targeting multiple myeloma2018
- Author(s)
  Shancer Zoe、Williams Matthew、Igelman Austin、Nagata Satoshi、Ise Tomoko、Pastan Ira、Bera Tapan K
- Journal Title
  
  Antibody Therapeutics
  
  Volume: 1 Issue: 1 Pages: 19-25
- DOI
  10.1093/abt/tby004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08300, KAKENHI-PROJECT-16K07158

1. FUKUI Yasuhisa (00181248)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Tsunoda Shin-ichi (90357533)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 井上雅己 (80757097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. IHARA Sayoko (80292788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 鎌田春彦 (00324509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中山泰亮 (90467598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nagata Satoshi 永田 諭志

NAGATA Satoshi 永田 諭志

永田 諭志 ナガタ サトシ

Research Projects

Research Products

Co-Researchers

2型TNF受容体を介する免疫制御機構の解明とがん免疫療法への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of antibody design optimized for active targeting

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of TNFR2-APP3 signaling pathway and and its immuno-suppressive function

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional antibodies against membrane receptors expressed on regulatory T cells in correlation with immunosuppressive functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on signal transduction in generation and development of cancers.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞の分化・増殖における3'リン酸化イノシトールリン脂質の役割

Principal Investigator

Project Period (FY)

Research Category

Research Institution

細胞の増殖・分化における3′-リン酸化イノシトールリン脂質の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

水疱性口内炎ウイルス膜糖タンパク質の細胞融合能に関わる抗原エピトープの同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 高効率な臨床抗体の開発を目指して2019

Author(s)

Journal Title

Data Source

[Journal Article] Anti-BCMA immunotoxins produce durable complete remissions in two mouse myeloma models2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Differentiation in vitro of Human Tonsil B Cells With the Phenotypic and Functional Characteristics of T-bet+ Atypical Memory B Cells in Malaria2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of allotypic variation of human IgG1 on the thermal stability of disulfide-linked knobs-into-holes mutants of the Fc for stable bispecific antibody design2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical significance of MUC13 in pancreatic ductal adenocarcinoma2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Longitudinal autoantibody responses against tumor-associated antigens decrease in breast cancer patients according to treatment modality2018

Author(s)

Journal Title

Nagata Satoshi 永田諭志

NAGATA Satoshi 永田諭志

永田諭志ナガタサトシ