YAGI Hideki 八木秀樹

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Researcher Number	40250740
Other IDs
Affiliation (Current)	2020: 国際医療福祉大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 国際医療福祉大学, 薬学部, 教授 2007: Kinki University, School of Pharmacy, Associate Professor 2004 – 2006: Kinki University, School of Pharmaceutical Sciences, Lecturer, Ph, D., 薬学部, 講師 2003: 近畿大学, 薬学部, 助手 2000: 近畿大学, 薬学部, 助手 … More
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / 細胞死(アポトーシス) / Medical pharmacy / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator General anatomy (including Histology/Embryology) / Biological pharmacy / Morphological basic dentistry
Keywords	Principal Investigator Tリンパ球 / CTSマウス / 移出能 / 胸腺 / 免疫不全 / apoptosis / FK506 / nude mouse / scid mouse / 胸線 … More Except Principal Investigator 破骨細胞 / マクロファージ / 胸腺 / 細胞死 / Thymus / Thymocytes / Differentiation / Selection / Clonal deletion / Microenvironment / Apoptosis / Cell death / 好中球 / MMP / ビスフオスフオネート / 赤血球造血 / 顆粒球 / 骨髄 / 脾臓 / アポトーシス誘導剤 / 細胞内カリウムイオン / ジギトキシン / 白血病細胞 / カリウム指示薬 / フローサイトメーター / 強心配糖体 / 抗癌作用 / カリウムイオン / モノクローナル抗体 / ビオチン化 / 胸腺リンパ球 / 分化 / 選択 / クローン排除 / 微小環境 / アポトーシス / apoptosis / pyknosis / 肢芽 / 小腸 / 慢性リウマチ性関節炎 / 骨破壊 / ビスフォスフォネート / コラーゲン誘導関節炎 / エラスターゼ / ビスフォスフォネト / 造血 / Rheumatoid Arthritis / Bone Destruction / Neutrophils / Bisphosphonate / Collagen-induced arthritis / Elastase / メッケル軟骨 / 形態形成 / 自己認識 / Meckel's cartilage / macrophage / Morohogenesis / neutrophil / self-recognition Less

Elucidation of possible mechanisms of lymphatic metastasis noted by a novel lymphangiogenic factorPrincipal InvestigatorOngoing
- Principal Investigator
  
  八木秀樹
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  International University of Health and Welfare
フィンゴリモドのアレルギー疾患への適用と免疫抑制を目指した抗体医薬品の開発Principal InvestigatorOngoing
- Principal Investigator
  
  八木秀樹
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  International University of Health and Welfare
Role of migrating cells for morphogenesis
- Principal Investigator
  
  NAKAMURA Masanori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Showa University
ビオチン化抗強心配糖体抗体による抗癌作用の増強
- Principal Investigator
  
  武智昌幸
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kinki University
Possible mechanisms of induction of apoptosis in enterocytes by intraepithelial lymphocytes.Principal Investigator
- Principal Investigator
  
  YAGI Hideki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  細胞死(アポトーシス)
- Research Institution
  Kinki University
Analysis of the mechanism of bone destruction by neutrophils
- Principal Investigator
  
  NAKAMURA Masanori
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Showa University
  Tohoku University
Mechanisms of pyknotic cell death in vivo and their biological significance
- Principal Investigator
  
  ITOH Tsunetoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  TOHOKU UNIVERSITY
先天性免疫不全マウス(CTS)の胸腺リンパ球の胸腺難移出性機構の解析Principal Investigator
- Principal Investigator
  
  八木秀樹
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
免疫不全マウス(CTS)の末梢Tリンパ球減少機構の解析-特に胸線の生後発生における変化について-Principal Investigator
- Principal Investigator
  
  八木秀樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
Microenvironment for thymocyte differentiation, selection and clonal elimination
- Principal Investigator
  
  ITOH Tsunetoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
アミノビスフオスフオネートの赤血球造血特にマクロファージへの効果
- Principal Investigator
  
  NAKAMURA Masanori
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University
先天性免疫不全マウス(CTS)のTリンパ球減少メカニズムの解析Principal Investigator
- Principal Investigator
  
  八木秀樹
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tohoku University

All 2019 2018 2017 2016 2008 2004 Other

All Journal Article Presentation

[Journal Article] Phloroglucinol derivatives and a chromone glucoside from the leaves of Myrtus communis2018
- Author(s)
  Tanaka Naonobu、Jia Yuyu、Niwa Kanji、Imabayashi Kiyoshi、Tatano Yutaka、Yagi Hideki、Kashiwada Yoshiki
- Journal Title
  
  Tetrahedron
  
  Volume: 74 Pages: 117-123
- DOI
  10.1016/j.tet.2017.11.044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08337, KAKENHI-PROJECT-17K10028, KAKENHI-PROJECT-15K19181, KAKENHI-PROJECT-16K08409
[Journal Article] Inhibition of tumor formation and metastasis by a monoclonal antibody against lymphatic vessel endothelial hyaluronan receptor 12018
- Author(s)
  Hara Yuta、Torii Ryota、Ueda Shiho、Kurimoto Erina、Ueda Eri、Okura Hiroshi、Tatano Yutaka、Yagi Hideki、Ohno Yoshiya、Tanaka Toshiyuki、Masuko Kazue、Masuko Takashi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Pages: 3171-3182
- DOI
  10.1111/cas.13755
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08409, KAKENHI-PROJECT-17K10028
[Journal Article] Nitrogen-containing bisphosphonate induces a newly discovered hematopoietic structure in the omentum of an anemic mouse model by stimulating G-CSF production2017
- Author(s)
  Hirotada Otsuka, Hideki Yagi, Yasuo Endo, Satoshi Soeta, Naoko Nonaka, Masanori Nakamura.
- Journal Title
  
  Cell Tissue Res
  
  Volume: 367 Pages: 297-309
- DOI
  10.1007/s00441-016-2525-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20367, KAKENHI-PROJECT-16K08409, KAKENHI-PROJECT-15K11022
[Journal Article] YM155 exerts potent cytotoxic activity against quiescent (G0/G1) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1.2017
- Author(s)
  Ookura Miyuki、Fujii Tatsuya、Yagi Hideki、Ogawa Takuya、Kishi Shinji、Hosono Naoko、Shigemi Hiroko、Yamauchi Takahiro、Ueda Takanori、Yoshida Akira
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 111535-111550
- DOI
  10.18632/oncotarget.22871
- NAID
  120006469617
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08409, KAKENHI-PROJECT-16K08410
[Journal Article] Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance2016
- Author(s)
  Takamura, S., H. Yagi, Y. Hakata, C. Motozono, S. R. McMaster, T. Masumoto, M. Fujisawa, T. Chikaishi, J. Komeda, J. Itoh, M. Umemura, A. Kyusai, M. Tomura, T. Nakayama, D. L. Woodland, J. E. Kohlmeier, and M. Miyazawa
- Journal Title
  
  J Exp Med.
  
  Volume: 213 Pages: 3057-3073
- DOI
  10.1084/jem.20160938
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01268, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H05199, KAKENHI-PROJECT-15K19116, KAKENHI-PROJECT-16K08409, KAKENHI-PROJECT-16K08821, KAKENHI-PROJECT-16K08850
[Journal Article] Simultaneous induction of apoptotic,autophagic,and necrosis-like cell death by monoclonal antibodies recognising chicken transferrin receptor2008
- Author(s)
  Ohno Y., Yagi H., Nakamura M., et. al.
- Journal Title
  
  Biochem Biophys Res Commun. 367・4
  
  Pages: 775-781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592008
[Journal Article] Simultaneous induction of apoptotic, autophagic, and necrosis-like cell death by monoclonal antibodies recognizing chicken transferrin receptor2008
- Author(s)
  Ohno, Y, Yagi, H, Nakamura, M, Masuko, K, Hashimoto, Y, Masuko, T
- Journal Title
  
  Biochem Biophys Res Commun 367
  
  Pages: 775-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592008
[Journal Article] Simultaneous induction of apoptotic,autophagic,and necrosis-like cell death by monoclonal antibodies recognizing chicken transferrin receptor2008
- Author(s)
  Ohno Y, Yagi H, Nakamura M., et. al.
- Journal Title
  
  Biochem Biophys Res Commun. 367
  
  Pages: 775-781
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592008
[Journal Article] Cell-death-inducing monoclonal antibodies raised against DT40 tumor cells : Identification of chicken transferrin receptor as a novel cell-death receptor2008
- Author(s)
  Ohno, Y, Yagi, H, Nakamura, M, Masuko, K, Hashimoto, Y, Masuko, T
- Journal Title
  
  Cancer Sci (in press)
- NAID
  10024005796
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592008
[Journal Article] Expression of CD98 amino acid transporter on murine haematopoietic stem cells.2004
- Author(s)
  Yagi, H., et al.
- Journal Title
  
  Cytometry Research 14
  
  Pages: 57-62
- NAID
  10026899700
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15603007
[Journal Article] Expression of CD98 amino acid transporter on murine haematopoietic stem cells2004
- Author(s)
  Yagi, H., Masuko, T.
- Journal Title
  
  Cytometry Research 14
  
  Pages: 57-62
- NAID
  10026899700
- Data Source
  KAKENHI-PROJECT-15603007
[Journal Article] Morphological and functional alteration of enterocytes by the daily administration of FK506 : Application of UV-excited alkaline phosphatase substrate, ELF 97 phosphate.2004
- Author(s)
  Yagi, H., et al.
- Journal Title
  
  Cytometry Research 14
  
  Pages: 41-46
- NAID
  10026899552
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15603007
[Journal Article] Morphological and functional alteration of enterocytes by the daily administration of FK506:Application of UV-excited alkaline phosphatase substrate, ELF 97 phosphate2004
- Author(s)
  Yagi, H., Hidaka, M.et al.
- Journal Title
  
  Cytometry Research 14
  
  Pages: 41-46
- NAID
  10026899552
- Data Source
  KAKENHI-PROJECT-15603007
[Journal Article] Noimprovement of bone destruction in collagen-induced arthritis by bisphosphonates
- Author(s)
  Nakayama M, Yagi H, Endo Y, Maki K, Nakamura M
- Journal Title
  
  Histology and Histopathology (in press)
- Data Source
  KAKENHI-PROJECT-18592008
[Presentation] 高リンパ節転移ヒト乳癌細胞株由来新規リンパ管新生因子の探索2019
- Author(s)
  百百純里奈、池内晶哉、三浦眞今子、常田百合、松本光史、益子高、多田納豊、八木秀樹
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08409

1. NAKAMURA Masanori (50180394)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
2. ITOH Tsunetoshi (90004746)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MASUKO Takashi (30157200)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. SOGA Hiroyuki (20282121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KONDO Shintaro (60186848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. EGAWA Kaoru (60119162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NONAKA Naoko (20307052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 武智昌幸 (00140343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OTSUKA Hirotada

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. KASHIWADA Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. TANAKA Naonobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. TATANO Yutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. TAKAMURA Shiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. TOMURA Michio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. MIYAZAWA Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 吉田明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 宮澤正顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 中山俊憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 博多義之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 本園千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results