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OSATOMI Kiyoshi  長富 潔

ORCIDConnect your ORCID iD *help
… Alternative Names

長冨 潔  オサトミ キヨシ

長富 潔  オサトミ キヨシ

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Researcher Number 40253702
Other IDs
External Links
Affiliation (Current) 2025: 長崎大学, 総合生産科学研究科(水産学系), 教授
Affiliation (based on the past Project Information) *help 2017 – 2023: 長崎大学, 水産・環境科学総合研究科(水産), 教授
2013 – 2015: 長崎大学, 水産・環境科学総合研究科(水産), 教授
2011 – 2012: 長崎大学, 水産・環境科学総合研究科, 教授
2011: 長崎大学, 大学院・水産・環境科学総合研究科, 教授
2011: 長崎大学, 大学院水産・環境科学総合研究科, 教授 … More
2006 – 2010: 長崎大学, 水産学部, 教授
2001 – 2004: 長崎大学, 水産学部, 助教授
2000: 長崎大学, 大学院・生産科学研究科, 助手
1997: 長崎大, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 40040:Aquatic life science-related / Aquatic life science / Fisheries chemistry / Fisheries chemistry
Except Principal Investigator
Fisheries chemistry / Basic Section 38050:Food sciences-related / 食品科学・栄養科学 / Fisheries chemistry
Keywords
Principal Investigator
酸化ストレス / プロモーター / 細胞培養系 / 魚病細菌 / 抗酸化酵素 / Edwardsiella tarda / flagellin / 活性酸素生成系 / 転写制御因子 / 魚類 … More / SOD / クローニング / 培養細胞系 / 宿主免疫回避 / 転写制御 / マクロファージ系細胞株 / プログラム細胞死 / 免疫応答 / Oxidative stress / Bacterial infection / Fish disease / Cloning / Purification / Fish / Superoxide dismutase / スーパーオキシドジムターゼ / 細菌感染症 / 魚病 / 精製 / スーパーオキシドジスムターゼ / 遺伝子構造 / 活性酸素 … More
Except Principal Investigator
火戻り / プロテアーゼ / cDNAクローニング / すり身 / ピロールアルカロイド / 海洋天然物 / プロテアーゼインヒビター / 魚肉ねり製品 / 水晒し / ブリ / TIMP-2 / MT1-MMP / トリプシン阻害剤 / 大豆タンパク質 / トリプシン / イトヨリダイ / セリンプロテアーゼ / Immunoblotting / Actin / Myosin / Colloidal gold / Electron microscope / Immuno-electron microscope / Himodori / Kamaboko / マダイ / 光学顕微鏡 / 抗原性 / 組織 / 物性 / カマボコ / マエソ / イムノブロット / アクチン / ミオシン / 金コロイド / 電子顕微鏡 / 免疫電子顕微鏡 / かまぼこ / Serine proteinase inhibitor / Modori / Trypsin type protease / Lizard fish / Carp / Amino acid sequence / Molecular cloning / Myofibril-bound serine protease / プローブ / 精製 / N末端アミノ酸配列 / 筋原繊維結合型セリンプロテアーゼ / mRNA発現 / セリン型酵素インヒビター / 戻り / トリプシン型酵素 / エソ / コイ / 一次構造 / 遺伝子クローニング / 筋原線維結合型セリンプロテアーゼ / 海産天然物 / ラメラリン / 分子設計 / トポイソメラーゼI阻害 / 生理活性物質 / 天然物化学 / ディクティオデンドリン / 合成 / テロメラーゼ阻害活性 / 生理活性 / ATPase / 組織化学 / 養殖ブリ / 肉質低下 / カテプシン / ヤケ肉 / 筋原線維タンパク質 / やけ肉 Less
  • Research Projects

    (15 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (11 People)
  •  Properties and quality development of frozen surimi made of yellowtail as a new raw material

    • Principal Investigator
      吉田 朝美
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Nagasaki University
  •  エドワジエラ症原因菌の宿主免疫回避戦略-酸化ストレスとプログラム細胞死から探る-Principal Investigator

    • Principal Investigator
      長富 潔
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 40040:Aquatic life science-related
    • Research Institution
      Nagasaki University
  •  Quality improvement of the threadfin bream surimi: Identification and characterization of the major factor for its quality loss

    • Principal Investigator
      Yoshida Asami
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Nagasaki University
  •  Elucidation of the mechanism of evasion of the host immune response by the causative bacteria of Edwardsiellosis in fishes - From the viewpoint of reactive oxygen generation system -Principal Investigator

    • Principal Investigator
      OSATOMI Kiyoshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 40040:Aquatic life science-related
    • Research Institution
      Nagasaki University
  •  Molecular mechanism of the oxidative stress response caused by the anti-oxidant enzyme in fish - Molecular biological approach -Principal Investigator

    • Principal Investigator
      OSATOMI Kiyoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Aquatic life science
    • Research Institution
      Nagasaki University
  •  Molecular mechanism of the defense systems against host immunity by causative bacillus of Edwardsiellosis in fishes - Cell biological approach -Principal Investigator

    • Principal Investigator
      OSATOMI Kiyoshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Aquatic life science
    • Research Institution
      Nagasaki University
  •  Mechanism of gene expression regulation of anti-oxidant enzymeswith oxidative stress in fishes - Molecular cell biological approach -Principal Investigator

    • Principal Investigator
      OSATOMI Kiyoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Fisheries chemistry
    • Research Institution
      Nagasaki University
  •  Design and synthesis of novel anticancer compound based on the molecular mode of action of the marine pyrrole alkaloid lamellarin

    • Principal Investigator
      ISHIBASHI Fumito
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Fisheries chemistry
    • Research Institution
      Nagasaki University
  •  Response mechanism of anti-oxidant enzymes with bacterial infection in fishes-Cell biological approach -Principal Investigator

    • Principal Investigator
      OSATOMI Kiyoshi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Fisheries chemistry
    • Research Institution
      Nagasaki University
  •  Design and synthesis of telomerase inhibitors based on marine alkaloides

    • Principal Investigator
      ISHIBASHI Fumito
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Fisheries chemistry
    • Research Institution
      Nagasaki University
  •  Studies on mechanism of burnt meat caused by seawater warming in cultured yellowtail (Seriola quinqueradita)-enzymatic approach

    • Principal Investigator
      HARA Kenji
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Fisheries chemistry
    • Research Institution
      Nagasaki University
  •  Studies on the distribution of structural proteins in himodori kamaboko by immuno-electron microscopic technique and physical properties

    • Principal Investigator
      TACHIBANA Katsuyasu, TSUCHIMOTO Mutsuyosi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      食品科学・栄養科学
    • Research Institution
      Nagasaki University
  •  Study on structure and function of myofibril-bound serine proteinase (MBP) using molecular cloning

    • Principal Investigator
      HARA Kenji
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Fisheries chemistry
    • Research Institution
      Nagasaki University
  •  Studies on superoxide dismutase and oxidative stress response in fishesPrincipal Investigator

    • Principal Investigator
      OSATOMI Kiyoshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Fisheries chemistry
    • Research Institution
      Nagasaki University
  •  魚類の酵素的生体防御能及びスーパーオキシドジスムターゼに関する研究Principal Investigator

    • Principal Investigator
      長富 潔
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Fisheries chemistry
    • Research Institution
      Nagasaki University

All 2024 2023 2022 2021 2020 2019 2017 2012 2011 2010 2009 2008

All Journal Article Presentation Book

  • [Book] Effect of Bacterial Infection on the Expression of Stress Proteins and Antioxidative Enzymes in Japanese flounder. H.-J. Ceccaldi et al. (eds.), Evolution of Marine Coastal Ecosystems under the Pressure of Global Changes2020

    • Author(s)
      Toshiki Nakano, Kiyoshi Osatomi, Nanami Miura, Yoko Aikawa-Fukuda, Kinya Kanai, Asami Yoshida, Hitoshi Shirakawa, Akiko Yamauchi, Toshiyasu Yamaguchi, and Yoshihiro Ochiai
    • Total Pages
      17
    • Publisher
      Springer-Nature AG
    • Data Source
      KAKENHI-PROJECT-20K06228
  • [Book] Effect of Bacterial Infection on the Expression of Stress Proteins and Antioxidative Enzymes in Japanese flounder. H.-J. Ceccaldi et al. (eds.), Evolution of Marine Coastal Ecosystems under the Pressure of Global Changes2020

    • Author(s)
      Toshiki Nakano, Kiyoshi Osatomi, Nanami Miura, Yoko Aikawa-Fukuda, Kinya Kanai, Asami Yoshida, Hitoshi Shirakawa, Akiko Yamauchi, Toshiyasu Yamaguchi, and Yoshihiro Ochiai
    • Publisher
      Springer-Nature AG
    • Data Source
      KAKENHI-PROJECT-17K07940
  • [Journal Article] Transcriptional regulation of the Japanese flounder Cu,Zn-SOD (Jfsod1) gene in RAW264.7 cells during oxidative stress caused by causative bacteria of edwardsiellosis2024

    • Author(s)
      Sun Xiao-Mi、Yoshida Asami、Ishii Takuya、Jiang Yan-Rong、Gao Yi-Li、Ueno Mikinori、Hirasaka Katsuya、Osatomi Kiyoshi
    • Journal Title

      Biochimie

      Volume: 218 Pages: 118-126

    • DOI

      10.1016/j.biochi.2023.09.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K05395
  • [Journal Article] Cloning, DNA sequence, and expression of flagellins from high and low virulence strains of Edwardsiella tarda and their macrophage-stimulating activities2023

    • Author(s)
      Xiao-Mi Sun, Asami Yoshida, Fukutarou Toutani, Takahiro Shimizu, Tatsuya Oda, Kiyoshi Osatomi
    • Journal Title

      Microbial Pathogenesis

      Volume: 176 Pages: 105993-105993

    • DOI

      10.1016/j.micpath.2023.105993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K06228
  • [Journal Article] Identification of a Tissue Inhibitor of Metalloproteinase-2: An Endogenous Inhibitor of <i>Modori</i>-Inducing Insoluble Metalloproteinase from Yellowtail <i>Seriola quinqueradiata</i> Muscle2023

    • Author(s)
      Jiang Yan-Rong、Yoshida Asami、Sun Xiao-Mi、Higashitani Hayato、Yamada Kairi、Miyazaki Riho、Noguchi Erika、Kuwahara Koichi、Osatomi Kiyoshi
    • Journal Title

      Journal of Agricultural and Food Chemistry

      Volume: 71 Issue: 7 Pages: 3414-3423

    • DOI

      10.1021/acs.jafc.2c07803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K05113
  • [Journal Article] Identification of a modori-inducing proteinase in the threadfin bream: Molecular cloning, tissue distribution and proteinase leakage from viscera during ice storage.2020

    • Author(s)
      1)Jin-Yang Liu, Asami Yoshida, Yi-Li Gao, Kazuya Shirota, Yasuhiko Shiina, Kiyoshi Osatomi
    • Journal Title

      Food Chemistry

      Volume: 330 Pages: 127246-127246

    • DOI

      10.1016/j.foodchem.2020.127246

    • NAID

      120006988156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K05909
  • [Journal Article] Degradation of myofibrillar proteins in the belly muscle of the threadfin bream is caused by the possible leaking of soluble serine proteinase from the viscera during storage.2020

    • Author(s)
      4)Jin-Yang Liu, Asami Yoshida, Yi-Li Gao, Kazuya Shirota, Yasuhiko Shiina, Kiyoshi Osatomi
    • Journal Title

      Fisheries Science

      Volume: 86 Issue: 2 Pages: 407-414

    • DOI

      10.1007/s12562-019-01398-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K05909
  • [Journal Article] Purification molecular cloning, and some properties of a manganese-containing superoxide dismutase from Japanese flounder (Paralichthys olivaceus)2011

    • Author(s)
      Y. Wang, K. Osatomi, Y. Nagatomo, A. Yoshida, K. Hara.
    • Journal Title

      Comparative Biochemistry and Physiology Part B

      Volume: 158 Pages: 289-96

    • NAID

      120006984788

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580224
  • [Journal Article] Extracellular products from virulent strain of Edwardsiella tarda stimulate mouse macrophages (RAW264.7) to produce nitric oxide (NO) and tumor necrosis factor (TNF)-α.2010

    • Author(s)
      Y. Wang, K. Osatomi, A. Yoshida, X. Liang, K. Kanai, T. Oda, K. Hara
    • Journal Title

      Fish&Shellfish Immunology

      Volume: 29 Pages: 778-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22580224
  • [Journal Article] Comparative analysis of the production of nitric oxide (NO) and tumor necrosis factor-α(TNF-α) from macrophages exposed to high virulent and low virulent strains of Edwardsiella tarda.2009

    • Author(s)
      K. Ishibe, T. Yamanishi, Y. Wang, K. Osatomi, K. Hara, K. Kanai, K. Yamaguchi, T. Oda
    • Journal Title

      Fish&Shellfish Immunology Vol.27

      Pages: 386-389

    • NAID

      120006984058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580236
  • [Journal Article] Comparison of the responses of peritoneal macrophages from Japanese flounder ( Paralichthys olivaceus) against high virulent and low virulent strains of Edwardsiella tarda2008

    • Author(s)
      K. Ishibe, K. Osatomi, K. Hara, K. Kanai, K. Yamaguchi, T. Oda
    • Journal Title

      Fish Shellfish Immunol. 24

      Pages: 243-251

    • NAID

      120006983895

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580238
  • [Journal Article] Biochemical properties of acid-soluble collagens extracted from the skins of underutilized fishes2008

    • Author(s)
      I. Bae, K. Osatomi, A. Yoshida, K. Osako, A. Yamaguchi, K. Hara
    • Journal Title

      Food Chem 108

      Pages: 49-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580238
  • [Journal Article] Comparison of the responses of peritoneal macrophages from Japanese flounder (Paralichthys olivaceus) against high virulent and low virulent strains of Edwardsiella tarda.2008

    • Author(s)
      K. Ishibe, K. Osatomi, K. Hara, K. Kanai, K. Yamaguchi, T. Oda
    • Journal Title

      Fish&Shellfish Immunology Vol.24

      Pages: 243-251

    • NAID

      120006983895

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19580236
  • [Presentation] 酸化ストレスに伴うヒラメCu,Zn-SOD遺伝子のプロモーター解析2022

    • Author(s)
      Xiao-Mi Sun・吉田朝美・Yi-Li Gao・Yan-Rong Jiang・田丸悠文・長富 潔
    • Organizer
      令和3年度日本水産学会九州支部大会
    • Data Source
      KAKENHI-PROJECT-20K06228
  • [Presentation] 魚類エドワジエラ症原因菌Edwardsiella tarda が有する宿主免疫回避機構の解明2022

    • Author(s)
      田丸悠文・Xiao-Mi Sun・吉田朝美・長富 潔
    • Organizer
      第44回蛋白質と酵素の構造と機能に関する九州シンポジウム
    • Data Source
      KAKENHI-PROJECT-20K06228
  • [Presentation] The quality improvement of threadfin bream (Nemipterus virgatus) surimi-gel with soy protein as a natural food additive.2021

    • Author(s)
      Yi-Li Gao, Asami Yoshida, Shinnosuke Maeda, Jin-Yang Liu, Yan-Rong Jiang, Xiao-Mi Sun, Chao-Ping Chen, Yajun Wang, Tetsuhiko Okajima and Kiyoshi Osatomi
    • Organizer
      EAFTA 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K05909
  • [Presentation] E.tarda由来組換えflagellin刺激によるヒラメCu,Zn-SOD遺伝子の転写制御機構の解析2020

    • Author(s)
      清水貴広・Gao Yili・吉田朝美・長富 潔
    • Organizer
      令和2年度日本水産学会九州支部大会
    • Data Source
      KAKENHI-PROJECT-20K06228
  • [Presentation] E.tarda由来flagellin刺激によるヒラメCu,Zn-SOD遺伝子の転写制御領域の解析2019

    • Author(s)
      清水貴広・吉田朝美・長富 潔
    • Organizer
      令和元年度日本水産学会秋季大会
    • Data Source
      KAKENHI-PROJECT-17K07940
  • [Presentation] 酸化ストレスに伴うヒラメMn-SOD遺伝子の発現制御領域の解析2017

    • Author(s)
      石橋侑里香・吉田朝美・長富 潔
    • Organizer
      平成29年度日本水産学会九州支部大会
    • Data Source
      KAKENHI-PROJECT-17K07940
  • [Presentation] E.tarda由来組換えflagellin暴露に伴うヒラメCu,Zn-SOD遺伝子のプロモーター活性の解析2017

    • Author(s)
      玉田佳子・吉田朝美・長富 潔
    • Organizer
      平成29年度日本水産学会九州支部大会
    • Data Source
      KAKENHI-PROJECT-17K07940
  • [Presentation] Studies on structure, function and pathological significance of antioxidant enzymes in fishes.2012

    • Author(s)
      K. Osatomi
    • Organizer
      2012 International Conference on Food Science
    • Place of Presentation
      Dalian, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-22580224
  • [Presentation] Studies on structure, function and pathological significance of antioxidant enzymes in fishes.2012

    • Author(s)
      K. Osatomi
    • Organizer
      International Conference on Food Science
    • Place of Presentation
      Dalian, China.
    • Year and Date
      2012-08-30
    • Data Source
      KAKENHI-PROJECT-22580224
  • [Presentation] 養殖ハマチやけ肉中のプロテアーゼに関する研究2009

    • Author(s)
      梁 簾, 吉田朝美, 長富 潔, 原 研治
    • Organizer
      平成21年度日本水産学会
    • Place of Presentation
      東京海洋大学
    • Year and Date
      2009-03-28
    • Data Source
      KAKENHI-PROJECT-18580207
  • [Presentation] Studies on proteases in cultured yellowtail (Seriola quinqueradiata) burnt meat2009

    • Author(s)
      Xiao Liang, Asami Yoshida, Kiyoshi Osatomi, Kenji Hara
    • Organizer
      The 7^<th> International Workshop on the Oceanography and Fisheries Science of the East China Sea
    • Place of Presentation
      Shanghai, China
    • Data Source
      KAKENHI-PROJECT-18580207
  • [Presentation] Studies on proteases in cultured yellowtail (Seriola quinqueradiata) burnt meat2009

    • Author(s)
      Xiao Liang, Asami Yoshida, Kiyoshi Osatomi, Kenji Hara
    • Organizer
      The 10^<th> Joint International Symposium between Pukyong National University and Nagasaki University
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-18580207
  • [Presentation] 養殖ハマチヤケ肉中のプロテアーゼに関する研究2009

    • Author(s)
      梁簫, 吉田朝美, 長富潔, 原研治
    • Organizer
      平成21年度日本水産学会春季大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18580207
  • 1.  HARA Kenji (10039737)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 8 results
  • 2.  YOSHIDA Asami (80589870)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 14 results
  • 3.  TACHIBANA Katsuyasu (20171712)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  ODA Tatsuya (60145307)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 5.  KANAI Kinya (40145222)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 6.  ISHIBASHI Fumito (10192486)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  ISHIHARA Tadashi (40039722)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  TSUCHIMOTO Mutsuyosi (20080525)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  平坂 勝也 (70432747)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 10.  HAMADA Yuki (90380831)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NOZAKI Yukinori (90039727)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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