Hino Jun 日野純

… Alternative Names

HINO Jun 日野純

日野純ヒノジュン

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Researcher Number	40260351
Other IDs	https://orcid.org/0000-0003-4740-8858
Affiliation (based on the past Project Information) *help	2015 – 2021: 国立研究開発法人国立循環器病研究センター, 研究所, 室長 2013 – 2014: 独立行政法人国立循環器病研究センター, 研究所, 室長 2010: 国立循環器病センター(研究所), 生化学部, 室長 2009 – 2010: National Cardiovascular Center Research Institute, 生化学部, 室長 2005 – 2008: National Cardiovascular Center Research Institute, Head of Biochemistry, 生化学部, 室長 … More 2007: National Cardiovascular Center Research Institute, 生化学部, 室長 2003 – 2004: National Cardiovascular Center Research Institute, Head of Biochemistry, 生化学部, 室長 2002: 国立循環器病センター研究所, 生化学部, 室員 1996 – 2000: 国立循環器病センター研究所, 生化学部, 室員 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Circulatory organs internal medicine / Endocrinology / Basic Section 56020:Orthopedics-related / Orthopaedic surgery Except Principal Investigator Basic Section 57010:Oral biological science-related / Cardiovascular medicine / Functional biochemistry
Keywords	Principal Investigator BMP-3b / BMP / 脂肪細胞 / 肥満 / 代謝 / TGF-b / 骨形成タンパク質 / CNP / arteriosclerosis / 血管平滑筋細胞 … More / 動脈硬化 / 骨代謝 / エネルギー消費 / 分化 / 分子型 / アディポサイトカイン / TGF-β / 脂肪肝炎 / Tg / 脂肪肝 / 骨代謝調節因子 / 骨代謝調節 / 血管内彼細胞 / インスリン抵抗性 / 糖尿病 / 線維化 / 炎症 / NASHインスリン抵抗性 / 抗炎症 / ペプチド / 臓器関連 / 臓器連関 / エネルギー代謝 / 血管内皮細胞 / 肥満・糖尿病 / cardiopoiesis / transgenic mice / splicing variant / vascular smooth muscle cells / トランスジェニックマウス / スプライシングバリアント / 心臓発生 / vascular smooth muscle cell / vascular calcification / cardiovascular system / 心血管系 / 石灰化 / 心・血管系 / biologically active peptide / bone metabolism / 生理活性ペプチド / 摂食 / エネルギー / 脂肪組織 / PPARγ / ＢＭＰ-3ｂ / 前駆体 / 内分泌 / 複合体 / 分化因子 / プロモーターアッセイ / 細胞分化 / 骨芽細胞 / LPS / 培養血管内皮細胞 / 培養血管平滑筋細胞 … More Except Principal Investigator 骨格筋組織幹細胞 / オーラルフレイル / 筋分化 / 萎縮 / 骨格筋 / 骨格筋代謝 / BMP3b / 筋再生 / サルコペニア / GDF10 / BMP-3b / BMP / グレリン / 循環調節 / 自律神経 / ニューロメジン / ペプチド / 酵素作用の機作 / 進化発生 / 発生遺伝 / 胚葉形成・原腸形成・体節形成 / 酵素の調節 / 発生・分化制御 / 形態形成 Less

骨代謝調節因子による肥満やそれに起因する脂肪肝炎の制御とその病態生理学的役割Principal Investigator
- Principal Investigator
  
  日野純
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  National Cardiovascular Center Research Institute
The mechanism of BMP-3b on regulating myogenesis of skeletal muscle stem cells
- Principal Investigator
  
  Kokabu Shoichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu Dental College
Control of obesity and energy metabolism by regulator of bone metabolism, and its physiological and pathological role.Principal Investigator
- Principal Investigator
  
  Hino Jun
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  National Cardiovascular Center Research Institute
Investigation of cardiovascular regulation and multiple function of gastrointestinal peptides
- Principal Investigator
  
  MIYAZATO Mikiya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Cardiovascular Center Research Institute
Analysis of physiological and pathological function of BMP-3b acts as novel adipocytokinePrincipal Investigator
- Principal Investigator
  
  Hino Jun
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  National Cardiovascular Center Research Institute
Axial patterning by a prohormone converting enzyme, PC6
- Principal Investigator
  
  NISHIMATSU Shin-Ichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kawasaki Medical School
Functional analysis of BMP-3b as a novel adipocytokinePrincipal Investigator
- Principal Investigator
  
  HINO Jun
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  National Cardiovascular Center Research Institute
Physiological and pathological analysis of BMP-3b in cardiovascular system.Principal Investigator
- Principal Investigator
  
  HINO Jun
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute
Biological and pathophysiological analysis of BMP-3b in cardiovascular system.Principal Investigator
- Principal Investigator
  
  HINO Jun
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute
The search for novel biologically active peptides that control bone metabolism.Principal Investigator
- Principal Investigator
  
  HINO Jun
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  National Cardiovascular Center Research Institute
新規骨形成タンパク質(BMP-3b)のレセプター同定およびBMP-3bの機能解析Principal Investigator
- Principal Investigator
  
  日野純
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  National Cardiovascular Center Research Institute
新規骨形成タンパク質(BMP-3b)の生体における生理作用及び作用機序の解明Principal Investigator
- Principal Investigator
  
  日野純
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  National Cardiovascular Center Research Institute
新しい骨形成タンパク質(BMP-3b)の生体における生理作用及び作用機序の解明Principal Investigator
- Principal Investigator
  
  日野純
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  National Cardiovascular Center Research Institute

[Journal Article] Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia2021
- Author(s)
  Uezumi Akiyoshi、Ikemoto-Uezumi Madoka、Zhou Heying、Kurosawa Tamaki、Yoshimoto Yuki、Nakatani Masashi、Hitachi Keisuke、Yamaguchi Hisateru、Wakatsuki Shuji、Araki Toshiyuki、Morita Mitsuhiro、Yamada Harumoto、Toyoda Masashi、Kanazawa Nobuo、Nakazawa Tatsu、Hino Jun、Fukada So-ichiro、Tsuchida Kunihiro
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 131 Issue: 1
- DOI
  10.1172/jci139617
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09614, KAKENHI-PROJECT-19K11710, KAKENHI-PROJECT-20K09423, KAKENHI-PROJECT-20K11247, KAKENHI-PROJECT-18K09122, KAKENHI-PROJECT-19H04063, KAKENHI-PROJECT-19H03427
[Journal Article] Inhibition of fibrotic changes in infrapatellar fat pad alleviates persistent pain and articular cartilage degeneration in monoiodoacetic acid-induced rat arthritis model2021
- Author(s)
  An J.-S.、Tsuji K.、Onuma H.、Araya N.、Isono M.、Hoshino T.、Inomata K.、Hino J.、Miyazato M.、Hosoda H.、Kangawa K.、Nakagawa Y.、Katagiri H.、Miyatake K.、Sekiya I.、Muneta T.、Koga H.
- Journal Title
  
  Osteoarthritis and Cartilage
  
  Volume: 29 Issue: 3 Pages: 380-388
- DOI
  10.1016/j.joca.2020.12.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09423, KAKENHI-PROJECT-19K18523, KAKENHI-PROJECT-18K09056, KAKENHI-PROJECT-19K18490, KAKENHI-PROJECT-19K18454
[Journal Article] Transgenic Expression of Bmp3b in Mesenchymal Progenitors Mitigates Age-Related Muscle Mass Loss and Neuromuscular Junction Degeneration2021
- Author(s)
  Kurosawa Tamaki、Minato Keitaro、Ikemoto-Uezumi Madoka、Hino Jun、Tsuchida Kunihiro、Uezumi Akiyoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 19 Pages: 10246-10246
- DOI
  10.3390/ijms221910246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09423, KAKENHI-PROJECT-19H03427, KAKENHI-PROJECT-19K09614, KAKENHI-PROJECT-21K19753
[Journal Article] Deficiency of natriuretic peptide signaling promotes peripartum cardiomyopathy-like remodeling in the mouse heart.2020
- Author(s)
  Otani K, Tokudome T, Kamiya CA, Mao Y, Nishimura H, Hasegawa T, Arai Y, Kaneko M, Shioi G, Ishida J, Fukamizu A, Osaki T, Nagai-Okatani C, Minamino N, Ensho T, Hino J, Murata S, Takegami M, Nishimura K, Kishimoto I, Miyazato M, Harada-Shiba M, Yoshimatsu J, Nakao K, Ikeda T, Kangawa K.
- Journal Title
  
  Circulation
  
  Volume: 141 Issue: 7 Pages: 571-588
- DOI
  10.1161/circulationaha.119.039761
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09543, KAKENHI-PROJECT-18K08127, KAKENHI-PROJECT-19K17727, KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-17H01566, KAKENHI-PROJECT-17K07131, KAKENHI-PROJECT-17K11041, KAKENHI-PROJECT-17K18414, KAKENHI-PROJECT-17K09897
[Journal Article] Oral Administration of Geranylgeraniol Rescues Denervation-induced Muscle Atrophy via Suppression of Atrogin-12020
- Author(s)
  MIYAWAKI AKI、ROJASAWASTHIEN THIRA、HITOMI SUZURO、AOKI YOSHINORI、URATA MARIKO、INOUE ASAKO、MATSUBARA TAKUMA、MORIKAWA KAZUMASA、HABU MANABU、TOMINAGA KAZUHIRO、KOKABU SHOICHIRO
- Journal Title
  
  In Vivo
  
  Volume: 34 Issue: 5 Pages: 2345-2351
- DOI
  10.21873/invivo.12047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09524
[Journal Article] C型ナトリウム利尿ペプチド（CNP)と慢性炎症疾患としての肥満・糖尿病2019
- Author(s)
  日野　純、宮里　幹也、寒川賢治
- Journal Title
  
  別冊 BIO Clinica　慢性炎症と疾患
  
  Volume: 8 Pages: 13-17
- Data Source
  KAKENHI-PROJECT-17K11041
[Journal Article] Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet.2018
- Author(s)
  Bae CR, Hino J, Hosoda H, Son C, Makino H, Tokudome T, Tomita T, Hosoda K, Miyazato M, Kangawa K.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2093-2093
- DOI
  10.1038/s41598-018-20469-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09897, KAKENHI-PROJECT-17K11041, KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-17K16159
[Journal Article] C-type natriuretic peptide (CNP) in endothelial cells attenuates hepatic fibrosis and inflammation in non-alcoholic steatohepatitis2018
- Author(s)
  Bae Cho-Rong、Hino Jun、Hosoda Hiroshi、Miyazato Mikiya、Kangawa Kenji
- Journal Title
  
  Life Sciences
  
  Volume: 209 Pages: 349-356
- DOI
  10.1016/j.lfs.2018.08.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11041, KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-17K16159
[Journal Article] Bone Morphogenetic Protein (BMP)-3b Gene Depletion Causes High Mortality in a Mouse Model of Neonatal Hypoxic-Ischemic Encephalopathy2018
- Author(s)
  Ogawa Yuko、Tsuji Masahiro、Tanaka Emi、Miyazato Mikiya、Hino Jun
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 9 Pages: 397-397
- DOI
  10.3389/fneur.2018.00397
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11041, KAKENHI-PROJECT-16H05306
[Journal Article] Myeloprotective effects of C-type natriuretic peptide on cisplatin-induced bone marrow granulocytopenia in mice.2017
- Author(s)
  Zenitani M, Nojiri T, Kimura T, Hosoda H, Miura K, Hino J, Nakahata K, Uehara S, Miyazato M, Oue T, Okuyama H, Kangawa K
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 79 Issue: 2 Pages: 363-368
- DOI
  10.1007/s00280-016-3221-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-16K10700
[Journal Article] Atrial natriuretic peptide protects against bleomycin-induced pulmonary fibrosis via vascular endothelial cells in mice : ANP for pulmonary fibrosis.2017
- Author(s)
  Okamoto A, Nojiri T, Konishi K, Tokudome T, Miura K, Hosoda H, Hino J, Miyazato M, Kyomoto Y, Asai K, Hirata K, Kangawa K
- Journal Title
  
  Respir Res
  
  Volume: 18 Issue: 1 Pages: 1-1
- DOI
  10.1186/s12931-016-0492-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-15K09185, KAKENHI-PROJECT-16K10700
[Journal Article] Overexpression of C-type Natriuretic Peptide in Endothelial Cells Protects against Insulin Resistance and Inflammation during Diet-induced Obesity.2017
- Author(s)
  Bae CR, Hino J, Hosoda H, Arai Y, Son C, Makino H, Tokudome T, Tomita T, Kimura T, Nojiri T, Hosoda K, Miyazato M, Kangawa K.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 9807-9807
- DOI
  10.1038/s41598-017-10240-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09897, KAKENHI-PROJECT-17K11041, KAKENHI-PROJECT-17K16159, KAKENHI-PROJECT-16H05306
[Journal Article] Identification of neuromedin U precursor-related peptide and its possible role in the regulation of prolactin release2017
- Author(s)
  Mori Kenji、Ida Takanori、Fudetani Mami、Mori Miwa、Kaiya Hiroyuki、Hino Jun、Nakahara Keiko、Murakami Noboru、Miyazato Mikiya、Kangawa Kenji
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-017-10319-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08124, KAKENHI-PROJECT-16H05043, KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-15K09445
[Journal Article] Overexpression of bone morphogenetic protein-3b (BMP-3b) in adipose tissues protects against high-fat diet-induced obesity.2017
- Author(s)
  Hino J, Nakatani M, Arai Y, Tsuchida K, Shirai M, Miyazato M, Kangawa K
- Journal Title
  
  Int J Obes
  
  Volume: 41 Issue: 4 Pages: 483-488
- DOI
  10.1038/ijo.2017.15
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-16K08599, KAKENHI-PROJECT-17K11041, KAKENHI-PROJECT-16H05126
[Journal Article] C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice.2016
- Author(s)
  Kimura T, Nojiri T, Hino J, Hosoda H, Miura K, Shintani Y, Inoue M, Zenitani M, Takabatake H, Miyazato M, Okumura M, Kangawa K.
- Journal Title
  
  Respiratory research
  
  Volume: 17 Issue: 1 Pages: 19-19
- DOI
  10.1186/s12931-016-0335-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-25461401, KAKENHI-PROJECT-26861135, KAKENHI-PROJECT-26293316
[Journal Article] Bone morphogenetic protein-3b (BMP-3b) is expressed in adipocytes and inhibits adipogenesis as a unique complex.2011
- Author(s)
  Hino J, Miyazawa T, Miyazato M, Kangawa K.
- Journal Title
  
  Int.J.Obesity doi.10.1038/ijo(in press)
  
  Pages: 124-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591107
[Journal Article] Regulator of G-protein signaling subtype 4 mediates antihypertrophic effect of locally secreted natriuretic peptides in the heart.2008
- Author(s)
  Tokudome T, Kishimoto I, Horio T, Arai Y, Schwenke DO, Hino J, Okano I, Kawano Y, Kohno M, Miyazato M, Nakao K, Kangawa K.
- Journal Title
  
  Circulation 117
  
  Pages: 2329-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591107
[Journal Article] Regulator of G-protein signaling subtype 4 mediates antihypertrophic effect of locally secreted natriuretic peptides in the heart.2008
- Author(s)
  Tokudome T, Kishimoto I, Horio T, Arai Y, Schwenke DO, Hino J, Okano I, Kawano Y, Kohno M, Miyazato M, Nakao K, Kangawa K.
- Journal Title
  
  Circulation 117
  
  Pages: 2329-2339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590830
[Journal Article] Upregulation of intracardiac adrenomedullin and its receptor system in rats with volume overload-induced cardiac hypertrophy.2005
- Author(s)
  Yoshihara F, Nishikimi T, Okano I, Hino J, Horio T, Tokudome T, Suga S, Matsuoka H, Kangawa K, Kawano Y.
- Journal Title
  
  Regulatory Peptides 127
  
  Pages: 239-244
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590728
[Journal Article] Bone morphogenetic protein-3 family members and their biological.2004
- Author(s)
  Hino J, Kangawa K, Matsuo H, Nohno T, Nishimatsu S.
- Journal Title
  
  Frontiers in Bioscience 9
  
  Pages: 1520-1529
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590728
[Journal Article] Bone morphogenetic protein-3 family members and their biological.2004
- Author(s)
  Hino J, et al.
- Journal Title
  
  Frontiers in Bioscience 9
  
  Pages: 1520-1529
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590728
[Journal Article] Bone morphogenetic protein-3 family members and their biological functions.2004
- Author(s)
  Hino J, et al.
- Journal Title
  
  Frontiers in Bioscience 9
  
  Pages: 1520-1529
- Data Source
  KAKENHI-PROJECT-16590728
[Presentation] CNPによる変形性関節症抑制効果の薬理学的作用機序の解明2022
- Author(s)
  野澤伊織、長谷川翔一、前原亜美、安宰成、日野純、中川裕介、宮武和正、片桐洋樹、中村智祐、早田匡芳、古賀英之、辻邦和
- Organizer
  第34回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K09423
[Presentation] ラット関節炎モデルにおけるC型ナトリウム利尿ペプチドの治療的効果の検討2021
- Author(s)
  長谷川翔一、辻邦和、安宰成、日野純、天野祐輔、中川裕介、宮武和正、片桐洋樹、中村智祐、関矢一郎、古賀英之
- Organizer
  第14回日本運動器疼痛学会
- Data Source
  KAKENHI-PROJECT-20K09423
[Presentation] 筋間質の間葉系前駆細胞の老化によるサルコペニアの発症機序2021
- Author(s)
  上住聡芳、上住円、黒澤珠希、日野純、深田宗一朗、土田邦博
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K09423
[Presentation] C型ナトリウム利尿ペプチド(CNP)はモノヨード酢酸によるラット関節炎モデルにおいて遷延痛を緩和する2021
- Author(s)
  長谷川翔一、辻邦和、安宰成、日野純、古賀英之
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K09423
[Presentation] Pain Persistence And Articular Cartilage Degeneration Were Significantly Alleviated By An Anti-fibrotic Drug Treatment In Monoiodoacetate Induced Rat Arthritis Model2020
- Author(s)
  Jaesung An; Kunikazu Tsuji; Hiroaki Onuma; Takashi Hoshino; Kei Inomata; Hiroki Katagiri; Kazumasa Miyatake; Yusuke Nakagawa; Jun Hino; Hiroshi Hosoda; Ichiro Sekiya; Takeshi Muneta; Hideyuki Koga
- Organizer
  ORS 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11041
[Presentation] 間質の間葉系前駆細胞が司る筋組織恒常性維持機構2020
- Author(s)
  上住聡芳、上住円、深田宗一朗、日野純、土田邦博
- Organizer
  第93回　日本薬理学会年会　シンポジウム
- Data Source
  KAKENHI-PROJECT-17K11041
[Presentation] 血管内皮細胞由来C型ナトリウム利尿ペプチド（CNP）は腎臓疾患による腎線維化を抑制する2020
- Author(s)
  延生　卓也、日野　純、白井　学、細田洋司、森　健二、南野　直人、宮里　幹也、寒川　賢治
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09423
[Presentation] C型ナトリウム利尿ペプチド（CNP）の肥満における抗炎症、インスリン抵抗性改善、エネルギー消費亢進作用2018
- Author(s)
  日野純、ベチョロン、細田洋司、孫徹、槙野久士、徳留健、冨田努、細田公則、宮里幹也、寒川賢治
- Organizer
  第23回アディポサイエンス・シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K11041
[Presentation] C型ナトリウム利尿ペプチド（CNP)の肥満・糖尿病における新たな作用2018
- Author(s)
  日野　純
- Organizer
  日本杜仲研究会　第13回定期大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11041
[Presentation] 間質の間葉系前駆細胞による骨格筋組織の健全性維持2018
- Author(s)
  上住聡芳、上住円、深田宗一郎、笠井健広、大野欽司、中谷直史、日野純、土田邦博
- Organizer
  第91回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11041
[Presentation] 血管内皮由来C型ナトリウム利尿ペプチド（CNP）の肥満における抗炎症、インスリン抵抗性改善、エネルギー消費亢進作用2017
- Author(s)
  ベチョロン、日野　純、細田　洋司、孫　徹、槙野　久士、徳留　健、富田　努、細田　公則、宮里　幹也、寒川　賢治
- Organizer
  第２１回日本心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-17K11041
[Presentation] C型ナトリウム利尿ペプチド（CNP）の高脂肪食性肥満における作用―脂肪細胞および血管内皮細胞特異的過剰発現マウスを用いた検討2017
- Author(s)
  ベチョロン、日野　純、宮里　幹也、寒川　賢治
- Organizer
  第９０回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K11041
[Presentation] 肥満におけるCNPの新たな作用―抗炎症、耐糖能改善、白色脂肪組織の褐色化作用―2017
- Author(s)
  ベチョロン、日野　純、細田　洋司、孫　徹、槙野　久士、徳留　健、富田　努、細田　公則、宮里　幹也、寒川　賢治
- Organizer
  第３８回日本肥満学会
- Data Source
  KAKENHI-PROJECT-17K11041
[Presentation] CNPの肥満における新たな作用-抗炎症、インスリン抵抗性改善、白色脂肪組織のBeige化作用2017
- Author(s)
  日野　純、ベチョロン、細田　洋司、孫　徹、槙野　久士、徳留　健、富田　努、細田　公則、宮里　幹也、寒川　賢治
- Organizer
  ２０１７年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K11041
[Presentation] 抗肥満・エネルギー消費亢進作用を示すBMP-3b過剰発現マウスの作用機序の検討2015
- Author(s)
  日野　純、中谷直史、荒井　勇二、土田　邦博、宮里　幹也、寒川　賢治
- Organizer
  第３８回日本分子生物学会年会、第８７回　日本生化学会合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] 抗肥満作用を示すBMP-3b過剰発現マウスの作用機序の検討2015
- Author(s)
  日野　純、中谷直史、荒井　勇二、土田　邦博、宮里　幹也、寒川　賢治
- Organizer
  第３６回　日本肥満学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-03
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] BMP-3bの新たなアディポサイトカインとしての抗肥満作用2015
- Author(s)
  日野　純、中谷直史、荒井　勇二、土田　邦博、宮里　幹也、寒川　賢治
- Organizer
  第19回日本心血管内分泌代謝学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] Bone morphogenetic protein-3b (BMP-3b) の新たな機能としての抗肥満作用2014
- Author(s)
  日野　純、宮澤　崇、宮里　幹也、寒川　賢治
- Organizer
  第28回　日本糖尿病・肥満動物学会
- Place of Presentation
  宮崎市、宮崎
- Invited
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] Bone morphogenetic protein-3b (BMP-3b) の新たなアディポカインとしての機能2013
- Author(s)
  日野　純、宮澤　崇、宮里　幹也、寒川　賢治
- Organizer
  第18回　アディポサイエンス・シンポジウム
- Place of Presentation
  豊中市、大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] BMP-3bの新規アディポカインとしての機能：過剰発現マウスによる抗肥満作用および代謝解析2013
- Author(s)
  日野　純、中谷直史、荒井　勇二、宮澤　崇、吉本　光佐、白井　幹康、土田　邦博、宮里　幹也、寒川　賢治
- Organizer
  第34回　日本肥満学会
- Place of Presentation
  千代田区、東京
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] 抗肥満作用を示すBMP-3b過剰発現マウスの機能解析及び脂肪細胞におけるBMP-3bの遺伝子発現調節2013
- Author(s)
  日野　純、中谷　直史、荒井　勇二、宮澤　崇、吉本　光佐、白井　幹康、土田　邦博、宮里　幹也、寒川　賢治
- Organizer
  第８６回　日本生化学会大会
- Place of Presentation
  横浜市、神奈川
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] BMP-3b functions as a novel adipocytokine that inhibits adipocyte differentiation by its unique complex2010
- Author(s)
  日野純
- Organizer
  8^<th> International Conference on BMPs
- Place of Presentation
  Leuven
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-20591107
[Presentation] Bone morphogenetic protein-3b (BMP-3b) is an adipocytokine secreted from preadipocytes and inhibits their differentiation2010
- Author(s)
  日野純
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  京都
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-20591107
[Presentation] BMP-3b過剰発現マウスを用いた脂肪組織における機能解析2010
- Author(s)
  日野純
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20591107
[Presentation] BMP-3b functions as a novel adipocytokine that inhibits adipocyte differentiation by its unique complex.2010
- Author(s)
  日野純
- Organizer
  8^<th> International Conference on BMPs
- Place of Presentation
  Leuven
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-20591107
[Presentation] Bone morphogenetic protein-3b(BMP-3b)is an adipocytokine secreted from preadipocytes and inhibits their differentiation.2010
- Author(s)
  日野純
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-20591107
[Presentation] BMP-3b過剰発現マウスを用いた脂肪組織における機能解析2010
- Author(s)
  日野純
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20591107
[Presentation] BMP-3bは脂肪細胞分化抑制作用を有する新たなアディポサイトカインである2009
- Author(s)
  日野純
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591107
[Presentation] BMP-3bは脂肪細胞分化抑制作用を有する新たなアディポサイトカインである2009
- Author(s)
  日野純
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591107
[Presentation] BMP-3bの脂肪細胞分化における遺伝子発現およびその新しい分泌型分子型の同定2008
- Author(s)
  日野純
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20591107
[Presentation] 誘導と自律分化によるセメント腺形成2008
- Author(s)
  西松伸一郎、日野純、寒川賢治、松尾壽之、濃野勉
- Organizer
  第41回日本発生生物学会大会サテライトシンポジウム「ツメガエルが拓く胚発生・形態形成研究の新展開」
- Place of Presentation
  徳島
- Year and Date
  2008-05-27
- Data Source
  KAKENHI-PROJECT-20570143
[Presentation] Different cement grand formation by BMP-3b and BMP-3.2007
- Author(s)
  Nishimatsu S, Hino J, Kangawa K, Matsuo H, Nohno T.
- Organizer
  The 30th Molecular Biology Society of Japan and The 80th Japan Biochemical Society
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590830
[Presentation] PC6, a BMP-3b-processing enzyme, is involved in axial patterning of the Xenopus embryo.2006
- Author(s)
  Nishimatsu S, Hino J, Kangawa K, Matsuo H, Nohno T.
- Organizer
  The 11th International Xanopus Conference
- Place of Presentation
  Chiba
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590830
[Presentation] Overexpression of BMP-3b in adiopose tissue prevents high-fat diet induced obesity with alteration of energy metabolism.
- Author(s)
  Jun Hino, Masashi Nakatani, Yuji Arai, Kunihiro Tsuchida, Mikiya Miyazato,
- Organizer
  10th International Conference on Bone Morphogenetic Proteins
- Place of Presentation
  Berlin, Germany
- Year and Date
  2014-09-16 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] BMP-3bの新たなアディポカインとしての脂肪細胞機能制御と抗肥満作用
- Author(s)
  日野　純、中谷直史、荒井　勇二、土田　邦博、宮里　幹也、寒川　賢治
- Organizer
  第３５回日本肥満学会
- Place of Presentation
  宮崎
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] Regulation of adipogenesis by BMP-3b in human rotator cuff derived cells
- Author(s)
  Atsuyuki Inui; Jun Hino ; Takeshi Kokubu; Yutaka Mifune; Mikiya Miyazato; Kenji Kangawa
- Organizer
  10th International Conference on Bone Morphogenetic Proteins
- Place of Presentation
  Berlin, Germany
- Year and Date
  2014-09-16 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25461401
[Presentation] 抗肥満作用を有するBMP-3b過剰発現マウスにおける脂肪細胞機能の解析
- Author(s)
  日野　純、中谷　直史、荒井　勇二、土田　邦博、宮里　幹也、寒川　賢治
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25461401

1. MIYAZATO Mikiya (50291183)

# of Collaborated Projects: 5 results

# of Collaborated Products: 26 results
2. KANGAWA Kenji (00112417)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
3. ARAI Yuji (30202724)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. NISHIMATSU Shin-Ichiro (20222185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. NOHNO Tsutomu (20098619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. SAGA Yumiko (50221271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAIYA Hiroyuki (40300975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Kokabu Shoichiro (30448899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 松原琢磨 (00423137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 小野悠介 (60601119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松尾拡 (70238971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 人見涼露 (70548924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. TOKUDOME Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
14. OTANI Kentaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. KAMIYA Chizuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 池本円

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 井田隆徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 細田洋司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hino Jun 日野 純

HINO Jun 日野 純

日野 純 ヒノ ジュン

Research Projects

Research Products

Co-Researchers

骨代謝調節因子による肥満やそれに起因する脂肪肝炎の制御とその病態生理学的役割Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

The mechanism of BMP-3b on regulating myogenesis of skeletal muscle stem cells

Principal Investigator

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Review Section

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Control of obesity and energy metabolism by regulator of bone metabolism, and its physiological and pathological role.Principal Investigator

Principal Investigator

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Research Institution

Investigation of cardiovascular regulation and multiple function of gastrointestinal peptides

Principal Investigator

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Analysis of physiological and pathological function of BMP-3b acts as novel adipocytokinePrincipal Investigator

Principal Investigator

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Research Institution

Axial patterning by a prohormone converting enzyme, PC6

Principal Investigator

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Research Institution

Functional analysis of BMP-3b as a novel adipocytokinePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Physiological and pathological analysis of BMP-3b in cardiovascular system.Principal Investigator

Principal Investigator

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Biological and pathophysiological analysis of BMP-3b in cardiovascular system.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

The search for novel biologically active peptides that control bone metabolism.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

新規骨形成タンパク質(BMP-3b)のレセプター同定およびBMP-3bの機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規骨形成タンパク質(BMP-3b)の生体における生理作用及び作用機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しい骨形成タンパク質(BMP-3b)の生体における生理作用及び作用機序の解明Principal Investigator

Principal Investigator

Hino Jun 日野純

HINO Jun 日野純

日野純ヒノジュン