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OKUBO Mitsuo  大久保 光夫

… Alternative Names

OKUBO Mituo  大久保 光夫

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Researcher Number 40260781
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9098-4477
External Links
Affiliation (Current) 2019: 順天堂大学, 医学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help 2007 – 2009: Saitama Medical University, 医学部, 准教授
2006: 埼玉医科大学, 医学部, 助教授
1998 – 2003: 埼玉医科大学, 医学部, 講師
1994 – 1997: 福島県立医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
内科学一般 / Laboratory medicine / Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology / Obstetrics and gynecology / Laboratory medicine
Keywords
Principal Investigator
T細胞 / エピトープ / SLE / HLA / HLA-DR / T cell epitope / human papillomavirus / cervical carcinoma / MCTD / 自己抗原 … More / mRNA / PCR / TNFα / T細胞レセプター / 膠原病 / リボヌクレオプロテイン / 全身性エリテマトーデス / 神経障害 / 腫瘍マーカー / 卵巣癌 / Th1,Th2 / 子宮癌 / Th1 / Th2 / ヒトパピローマウイルス / Th1, Th2 … More
Except Principal Investigator
パピローマウイルス / T細胞 / 子宮癌 / HLA / PCR-SSP / HPA-4 / IL-4 / T 細胞 / 免疫学 / ウイルス / エピトープ / 新生児血小板減少症 / 抗血小板抗体 / 羊水 / 遺伝子診断 / 出生前診断 / 胎児 / 血小板抗体 / 妊婦 / DNA診断 / 遺伝子増幅 / 血小板型 / プライマー / Neonatal alloimmune thrombocytopenia / Anti-platelet antibody / Amniotic fluid cells / Genotype / Prenatal diagnosis / fetus / Platelet / Alloimmunization / 卵巣癌 / 細胞療法 / 細胞治療 / Ovarian cancer / T cell / Cell therapy Less
  • Research Projects

    (10 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (8 People)
  •  卵巣癌腫瘍マーカーCA125を癌隔絶抗原とする活性化T細胞治療法に関する研究Principal Investigator

    • Principal Investigator
      大久保 光夫
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Saitama Medical University
  •  )A design of peptide-vaccine for cervical cancer based on patient's T cell responses, HLA type,and human papilloma virus genotype.

    • Principal Investigator
      MAEDA Hiroo
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Saitama Medical University
  •  Analysis of HLA-DRB1^*O901-binding HPV-16 E7 Helper T cell Epitope.Principal Investigator

    • Principal Investigator
      OKUBO Mitsuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Saitama Medical University
  •  Analysis of CD4+ T Cell Therapy for Advanced Ovarian Cancer followed Chemotherapy with PBSCT.

    • Principal Investigator
      MAEDA Hiroo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Saitama Medical University
  •  全身性エリテマトーデスにおける精神・神経障害発生機序の解明:HLA DR分子と親和性を持つ神経カドヘリンペプチドの解析Principal Investigator

    • Principal Investigator
      大久保 光夫
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Saitama Medical University
  •  パピローマウイルス抗原特異的細胞障害性リンパ球誘導による子宮頸癌治療の基礎的研究

    • Principal Investigator
      宍倉 祐子
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Saitama Medical University
  •  膠原病患者におけるT細胞レセプターの複数自己抗原認識機序の解明Principal Investigator

    • Principal Investigator
      大久保 光夫
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Saitama Medical University
      Fukushima Medical University
  •  個々の細胞内の特異的mRNAを検出する蛍光PCR法の確立Principal Investigator

    • Principal Investigator
      大久保 光夫
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Laboratory medicine
    • Research Institution
      Fukushima Medical University
  •  臓器非特異的な自己免疫疾患患者のT細胞が認識する自己抗原エピトープの解析Principal Investigator

    • Principal Investigator
      大久保 光夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Fukushima Medical University
  •  Prenatal Platelet Genotyping for Neonatal Alloimmune Thrombocytopenia.

    • Principal Investigator
      OHTA Hitoshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Fukushima Medical College

All 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

  • [Book] 血液製剤の考え方, 使い方2008

    • Author(s)
      大久保光夫
    • Total Pages
      351
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19659425
  • [Book] 輸血・細胞治療マニュアル2007

    • Author(s)
      大久保 光夫
    • Total Pages
      204
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19659425
  • [Book] よくわかる輸血学2005

    • Author(s)
      大久保光夫, 前田平生
    • Total Pages
      157
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] Unique Phenotypes of C1S Deficiency and Abnormality Caused by Two Compound Heterozygosities in a Japanese Family.2009

    • Author(s)
      Katsuaki Abe, Yuichi Endo, Naomi Nakazawa, Kazuko Kanno, Mitsuo Okubo, Tadashi Hoshino, Teizo Fujita
    • Journal Title

      Journal of Immunology 182

      Pages: 1681-1688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659425
  • [Journal Article] Association of human leukocyte antigen and T cell message with human papillomavirus 16-positive cervical neoplasia in Japanese women.2007

    • Author(s)
      Saito M, Okubo M, Hirata R, Takeda S, Maeda H.
    • Journal Title

      Int J Gynecol Cancer 17

      Pages: 1314-1321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] Association of human leukocyte antigen and T cell message with human papillomavirus 16-positive cervical neoplasia in Japanese women2007

    • Author(s)
      Saito M, Okubo M, Hirata R, Takeda S, Maeda H
    • Journal Title

      Int J Gynecol Cancer 17

      Pages: 1314-1321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] Association of human leukocyte antigen and T cell message with human papillomavirus 16-positive cervical neoplasia in Japanese women2007

    • Author(s)
      Saito M, Okubo M, Hirata R, Takeda S, Maeda H
    • Journal Title

      Int J Gynecol Cancer 17

      Pages: 1314-1321

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659425
  • [Journal Article] HLAタイピング2005

    • Author(s)
      大久保光夫, 前田平生
    • Journal Title

      臨床検査ガイド2005-2006 1

      Pages: 688-691

    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] 新鮮凍結血漿2005

    • Author(s)
      大久保光夫, 前田平生
    • Journal Title

      産科周術期管理のすべて 1

      Pages: 457-460

    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] 血小板輸血2005

    • Author(s)
      大久保光夫, 前田平生
    • Journal Title

      産科周術期管理のすべて 1

      Pages: 453-456

    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] 輸血,総論2005

    • Author(s)
      大久保光夫, 前田平生
    • Journal Title

      産科周術期管理のすべて 1

      Pages: 444-448

    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] 抗白血球抗体2005

    • Author(s)
      大久保光夫, 前田平生
    • Journal Title

      臨床検査ガイド2005-2006 1

      Pages: 676-678

    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] Analysis of HLA-DRB^*0901-binding HPV-16 E7 helper T cell epitope.2004

    • Author(s)
      Okubo M, Saito M, Inoku H, Hirata R, Yanagisawa M, Takeda S, Kinoshita K, Maeda H.
    • Journal Title

      Journal of Obstetrics and Gynecology Research 30

      Pages: 120-129

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671742
  • [Journal Article] Five-Year Results of Cyclic Semi-high Dose Chemotherapy Supported by Autologous Peripheral Blood Stem Cell Transplantation in Patients with Advanced Ovarian Cancer2004

    • Author(s)
      K Ikeba, M Okubo, S Takeda, K Kinoshita, H Maeda.
    • Journal Title

      International Journal of Clinical Oncology 9

      Pages: 113-119

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671742
  • [Journal Article] Analysis of HLA-DRB1 *090 1 -binding HPV-16 E7 Helper T cell Epitope.2004

    • Author(s)
      M Okubo, M Saito, H Inoku, R Hirata, M Yanagisawa, S Takeda, K Kinoshita, H Maeda.
    • Journal Title

      Journal of Obstetrics and Gynaecology Research 30

      Pages: 120-129

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671742
  • [Journal Article] Five-year results of cyclic semi-high dose chemotherapy supported by autologous peripheral blood stem cell transplantation in patients with advanced ovarian cancer.2004

    • Author(s)
      Ikeba K, Okubo M, Takeda S, Kinoshita K, Maeda H.
    • Journal Title

      International Journal of Oncology 9

      Pages: 113-119

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671742
  • [Journal Article] Analysis of HLA-DRB1*0901-binding HPV-16 E7 helper T cell epitope.2004

    • Author(s)
      Okubo M. Saito M. Inoku H. Hirata R. Yanagisawa M. Takeda S. Kinoshita K. Maeda H.
    • Journal Title

      J Obstet Gynaecol Res. 30

      Pages: 120-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] Human papillomavirus type 16 E6 variants and HLA class II alleles among Japanese women with cervical cancer.2003

    • Author(s)
      Matsumoto K, Yasugi T, Nakagawa S, Okubo M, Hirata R, Maeda H, Yoshikawa H,Taketani Y.
    • Journal Title

      Int J Cancer. 106

      Pages: 919-922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591756
  • [Journal Article] Human papillomavirus type 16 E6 variants and HLA class II alleles among Japanese womer with cervical cancer.2003

    • Author(s)
      K Matsumoto, T Yasugi, S Nakagawa, M Okubo, R Hirata, M Maeda, H Yoshikawa, Y Taketani.
    • Journal Title

      International Journal of Cancer 106

      Pages: 919-922

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671742
  • [Journal Article] Human papillomavirus type 16 E6 variants and HLA class II alleles among Japanese women with cervical cancer.2003

    • Author(s)
      Matsumoto K, Yasugi T, Nakagawa S, Okubo M, Hirata R, Maeda M, Yoshikawa H, Taketani Y.
    • Journal Title

      International Journal of Cancer 106

      Pages: 919-922

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671742
  • [Presentation] 臨床における細胞治療の最前線 進行卵巣癌に対するCA125抗原特異的T細胞活性化療法2009

    • Author(s)
      大久保光夫, 前田平生, 阿南昌弘, 鈴木康文, 平田蘭子, 柳沢雅美
    • Organizer
      第57回 日本輸血細胞治療学会総会
    • Place of Presentation
      埼玉県さいたま市
    • Year and Date
      2009-05-28
    • Data Source
      KAKENHI-PROJECT-19659425
  • [Presentation] 腫瘍マーカー内にエピトープを持つ抗原特異的T細胞による進行卵巣癌治療の研究2008

    • Author(s)
      大久保光夫, 柳沢雅実, 鈴木康文, 阿南昌弘, 平田蘭子, 前田平生
    • Organizer
      第56回日本輸血・細胞治療学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2008-04-25
    • Data Source
      KAKENHI-PROJECT-19659425
  • [Presentation] 卵巣癌抗原特異的T細胞による癌細胞障害活性の誘導2007

    • Author(s)
      大久保 光夫
    • Organizer
      第55回日本輸血・細胞治療学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-06-01
    • Data Source
      KAKENHI-PROJECT-19659425
  • [Presentation] 子宮頸癌患者におけるヒトパピローマウイルス16 型(HPV16)変異とHLA classII アリルとの関連2006

    • Author(s)
      松本光司, 八杉利治, 中川俊介, 大久保光夫, 平田蘭子, 前田平生, 武谷雄二, 吉川裕之
    • Organizer
      日本癌治療学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17591756
  • 1.  MAEDA Hiroo (30134597)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 2.  SAITO Maki (20301468)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 3.  TAKEDA Satoru (20143456)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  OHTA Hitoshi (20150279)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  UJIIE Niro (10168685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  ENDO Chikara (50168829)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  宍倉 祐子 (80181105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  木下 勝之 (80010354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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