Okubo Mitsuo 大久保光夫

… Alternative Names

Researcher Number	40260781
Other IDs	https://orcid.org/0000-0001-9098-4477
External Links
Affiliation (Current)	2021: 順天堂大学, 医学(系)研究科(研究院), 先任准教授
Affiliation (based on the past Project Information) *help	2020: 順天堂大学, 医学(系)研究科(研究院), 先任准教授 2007 – 2009: Saitama Medical University, 医学部, 准教授 2006: 埼玉医科大学, 医学部, 助教授 1998 – 2003: 埼玉医科大学, 医学部, 講師 1994 – 1997: 福島県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator 内科学一般 / Laboratory medicine / Obstetrics and gynecology / Basic Section 52010:General internal medicine-related Except Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology / Laboratory medicine
Keywords	Principal Investigator T細胞 / エピトープ / SLE / HLA / HLA-DR / T cell epitope / human papillomavirus / cervical carcinoma / MCTD / 自己抗原 … More Except Principal Investigator パピローマウイルス / T細胞 / 子宮癌 / HLA / PCR-SSP / HPA-4 / IL-4 / T 細胞 / 免疫学 / ウイルス / エピトープ / 新生児血小板減少症 / 抗血小板抗体 / 羊水 / 遺伝子診断 / 出生前診断 / 胎児 / 血小板抗体 / 妊婦 / DNA診断 / 遺伝子増幅 / 血小板型 / プライマー / Neonatal alloimmune thrombocytopenia / Anti-platelet antibody / Amniotic fluid cells / Genotype / Prenatal diagnosis / fetus / Platelet / Alloimmunization / 卵巣癌 / 細胞療法 / 細胞治療 / Ovarian cancer / T cell / Cell therapy Less

可溶型CD163分子による遊離ヘモグロビン細胞毒性回避機構解明と分子創薬への応用Principal Investigator
- Principal Investigator
  
  大久保光夫
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Juntendo University
卵巣癌腫瘍マーカーCA125を癌隔絶抗原とする活性化T細胞治療法に関する研究Principal Investigator
- Principal Investigator
  
  大久保光夫
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Saitama Medical University
)A design of peptide-vaccine for cervical cancer based on patient's T cell responses, HLA type,and human papilloma virus genotype.
- Principal Investigator
  
  MAEDA Hiroo
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Saitama Medical University
Analysis of HLA-DRB1^*O901-binding HPV-16 E7 Helper T cell Epitope.Principal Investigator
- Principal Investigator
  
  OKUBO Mitsuo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical University
Analysis of CD4+ T Cell Therapy for Advanced Ovarian Cancer followed Chemotherapy with PBSCT.
- Principal Investigator
  
  MAEDA Hiroo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Saitama Medical University
全身性エリテマトーデスにおける精神・神経障害発生機序の解明:HLA DR分子と親和性を持つ神経カドヘリンペプチドの解析Principal Investigator
- Principal Investigator
  
  大久保光夫
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical University
パピローマウイルス抗原特異的細胞障害性リンパ球誘導による子宮頸癌治療の基礎的研究
- Principal Investigator
  
  宍倉祐子
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Saitama Medical University
膠原病患者におけるT細胞レセプターの複数自己抗原認識機序の解明Principal Investigator
- Principal Investigator
  
  大久保光夫
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Saitama Medical University
  Fukushima Medical University
個々の細胞内の特異的mRNAを検出する蛍光PCR法の確立Principal Investigator
- Principal Investigator
  
  大久保光夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fukushima Medical University
臓器非特異的な自己免疫疾患患者のT細胞が認識する自己抗原エピトープの解析Principal Investigator
- Principal Investigator
  
  大久保光夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Fukushima Medical University
Prenatal Platelet Genotyping for Neonatal Alloimmune Thrombocytopenia.
- Principal Investigator
  
  OHTA Hitoshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fukushima Medical College

All 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

[Book] 血液製剤の考え方, 使い方2008
- Author(s)
  大久保光夫
- Total Pages
  351
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19659425
[Book] 輸血・細胞治療マニュアル2007
- Author(s)
  大久保光夫
- Total Pages
  204
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19659425
[Book] よくわかる輸血学2005
- Author(s)
  大久保光夫, 前田平生
- Total Pages
  157
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] Unique Phenotypes of C1S Deficiency and Abnormality Caused by Two Compound Heterozygosities in a Japanese Family.2009
- Author(s)
  Katsuaki Abe, Yuichi Endo, Naomi Nakazawa, Kazuko Kanno, Mitsuo Okubo, Tadashi Hoshino, Teizo Fujita
- Journal Title
  
  Journal of Immunology 182
  
  Pages: 1681-1688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659425
[Journal Article] Association of human leukocyte antigen and T cell message with human papillomavirus 16-positive cervical neoplasia in Japanese women.2007
- Author(s)
  Saito M, Okubo M, Hirata R, Takeda S, Maeda H.
- Journal Title
  
  Int J Gynecol Cancer 17
  
  Pages: 1314-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] Association of human leukocyte antigen and T cell message with human papillomavirus 16-positive cervical neoplasia in Japanese women2007
- Author(s)
  Saito M, Okubo M, Hirata R, Takeda S, Maeda H
- Journal Title
  
  Int J Gynecol Cancer 17
  
  Pages: 1314-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] Association of human leukocyte antigen and T cell message with human papillomavirus 16-positive cervical neoplasia in Japanese women2007
- Author(s)
  Saito M, Okubo M, Hirata R, Takeda S, Maeda H
- Journal Title
  
  Int J Gynecol Cancer 17
  
  Pages: 1314-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659425
[Journal Article] HLAタイピング2005
- Author(s)
  大久保光夫, 前田平生
- Journal Title
  
  臨床検査ガイド2005-2006 1
  
  Pages: 688-691
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] 新鮮凍結血漿2005
- Author(s)
  大久保光夫, 前田平生
- Journal Title
  
  産科周術期管理のすべて 1
  
  Pages: 457-460
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] 血小板輸血2005
- Author(s)
  大久保光夫, 前田平生
- Journal Title
  
  産科周術期管理のすべて 1
  
  Pages: 453-456
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] 輸血,総論2005
- Author(s)
  大久保光夫, 前田平生
- Journal Title
  
  産科周術期管理のすべて 1
  
  Pages: 444-448
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] 抗白血球抗体2005
- Author(s)
  大久保光夫, 前田平生
- Journal Title
  
  臨床検査ガイド2005-2006 1
  
  Pages: 676-678
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] Analysis of HLA-DRB^*0901-binding HPV-16 E7 helper T cell epitope.2004
- Author(s)
  Okubo M, Saito M, Inoku H, Hirata R, Yanagisawa M, Takeda S, Kinoshita K, Maeda H.
- Journal Title
  
  Journal of Obstetrics and Gynecology Research 30
  
  Pages: 120-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671742
[Journal Article] Five-Year Results of Cyclic Semi-high Dose Chemotherapy Supported by Autologous Peripheral Blood Stem Cell Transplantation in Patients with Advanced Ovarian Cancer2004
- Author(s)
  K Ikeba, M Okubo, S Takeda, K Kinoshita, H Maeda.
- Journal Title
  
  International Journal of Clinical Oncology 9
  
  Pages: 113-119
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671742
[Journal Article] Analysis of HLA-DRB1 *090 1 -binding HPV-16 E7 Helper T cell Epitope.2004
- Author(s)
  M Okubo, M Saito, H Inoku, R Hirata, M Yanagisawa, S Takeda, K Kinoshita, H Maeda.
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research 30
  
  Pages: 120-129
- NAID
  10013778772
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671742
[Journal Article] Five-year results of cyclic semi-high dose chemotherapy supported by autologous peripheral blood stem cell transplantation in patients with advanced ovarian cancer.2004
- Author(s)
  Ikeba K, Okubo M, Takeda S, Kinoshita K, Maeda H.
- Journal Title
  
  International Journal of Oncology 9
  
  Pages: 113-119
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671742
[Journal Article] Analysis of HLA-DRB1*0901-binding HPV-16 E7 helper T cell epitope.2004
- Author(s)
  Okubo M. Saito M. Inoku H. Hirata R. Yanagisawa M. Takeda S. Kinoshita K. Maeda H.
- Journal Title
  
  J Obstet Gynaecol Res. 30
  
  Pages: 120-129
- NAID
  10013778772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] Human papillomavirus type 16 E6 variants and HLA class II alleles among Japanese women with cervical cancer.2003
- Author(s)
  Matsumoto K, Yasugi T, Nakagawa S, Okubo M, Hirata R, Maeda H, Yoshikawa H,Taketani Y.
- Journal Title
  
  Int J Cancer. 106
  
  Pages: 919-922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591756
[Journal Article] Human papillomavirus type 16 E6 variants and HLA class II alleles among Japanese womer with cervical cancer.2003
- Author(s)
  K Matsumoto, T Yasugi, S Nakagawa, M Okubo, R Hirata, M Maeda, H Yoshikawa, Y Taketani.
- Journal Title
  
  International Journal of Cancer 106
  
  Pages: 919-922
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671742
[Journal Article] Human papillomavirus type 16 E6 variants and HLA class II alleles among Japanese women with cervical cancer.2003
- Author(s)
  Matsumoto K, Yasugi T, Nakagawa S, Okubo M, Hirata R, Maeda M, Yoshikawa H, Taketani Y.
- Journal Title
  
  International Journal of Cancer 106
  
  Pages: 919-922
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671742
[Presentation] 臨床における細胞治療の最前線進行卵巣癌に対するCA125抗原特異的T細胞活性化療法2009
- Author(s)
  大久保光夫, 前田平生, 阿南昌弘, 鈴木康文, 平田蘭子, 柳沢雅美
- Organizer
  第57回日本輸血細胞治療学会総会
- Place of Presentation
  埼玉県さいたま市
- Year and Date
  2009-05-28
- Data Source
  KAKENHI-PROJECT-19659425
[Presentation] 腫瘍マーカー内にエピトープを持つ抗原特異的T細胞による進行卵巣癌治療の研究2008
- Author(s)
  大久保光夫, 柳沢雅実, 鈴木康文, 阿南昌弘, 平田蘭子, 前田平生
- Organizer
  第56回日本輸血・細胞治療学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-19659425
[Presentation] 卵巣癌抗原特異的T細胞による癌細胞障害活性の誘導2007
- Author(s)
  大久保光夫
- Organizer
  第55回日本輸血・細胞治療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-19659425
[Presentation] 子宮頸癌患者におけるヒトパピローマウイルス16 型(HPV16)変異とHLA classII アリルとの関連2006
- Author(s)
  松本光司, 八杉利治, 中川俊介, 大久保光夫, 平田蘭子, 前田平生, 武谷雄二, 吉川裕之
- Organizer
  日本癌治療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17591756

1. MAEDA Hiroo (30134597)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
2. SAITO Maki (20301468)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. TAKEDA Satoru (20143456)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. OHTA Hitoshi (20150279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. UJIIE Niro (10168685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ENDO Chikara (50168829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 宍倉祐子 (80181105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 木下勝之 (80010354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 荒木慶彦 (70250933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Okubo Mitsuo 大久保 光夫

大久保 光夫 オオクボ ミツオ

OKUBO Mitsuo 大久保 光夫

OKUBO Mituo 大久保 光夫

Research Projects

Research Products

Co-Researchers

可溶型CD163分子による遊離ヘモグロビン細胞毒性回避機構解明と分子創薬への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

卵巣癌腫瘍マーカーCA125を癌隔絶抗原とする活性化T細胞治療法に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

)A design of peptide-vaccine for cervical cancer based on patient's T cell responses, HLA type,and human papilloma virus genotype.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of HLA-DRB1^*O901-binding HPV-16 E7 Helper T cell Epitope.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of CD4+ T Cell Therapy for Advanced Ovarian Cancer followed Chemotherapy with PBSCT.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

全身性エリテマトーデスにおける精神・神経障害発生機序の解明:HLA DR分子と親和性を持つ神経カドヘリンペプチドの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

パピローマウイルス抗原特異的細胞障害性リンパ球誘導による子宮頸癌治療の基礎的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

膠原病患者におけるT細胞レセプターの複数自己抗原認識機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

個々の細胞内の特異的mRNAを検出する蛍光PCR法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

臓器非特異的な自己免疫疾患患者のT細胞が認識する自己抗原エピトープの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prenatal Platelet Genotyping for Neonatal Alloimmune Thrombocytopenia.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 血液製剤の考え方, 使い方2008

Author(s)

Total Pages

Publisher

Data Source

[Book] 輸血・細胞治療マニュアル2007

Author(s)

Okubo Mitsuo 大久保光夫

大久保光夫オオクボミツオ

OKUBO Mitsuo 大久保光夫

OKUBO Mituo 大久保光夫