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Tkei Hiroyuki  武井 寛幸

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… Alternative Names

武井 寛幸  タケイ ヒロユキ

Takei Hiroyuki  武井 寛幸

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Researcher Number 40261846
Other IDs
External Links
Affiliation (Current) 2025: 日本医科大学, 大学院医学研究科, 大学院教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 日本医科大学, 大学院医学研究科, 大学院教授
2018 – 2020: 日本医科大学, 大学院医学研究科, 大学院教授
2014 – 2016: 日本医科大学, 医学(系)研究科(研究院), 教授
2000: 群馬大学, 医学部, 助手
1996 – 1998: 群馬大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
General surgery / Basic Section 50010:Tumor biology-related / Basic Section 55010:General surgery and pediatric surgery-related
Except Principal Investigator
Biomedical engineering/Biomaterial science and engineering
Keywords
Principal Investigator
血管新生 / 乳癌 / TNP-470 / 術前内分泌療法 / VEGF / UFT / Vascular endothelial growth factor / 血管新生阻害剤 / MDA-MB-231 / 糖代謝 … More / 腫瘍免疫 / 術前化学療法 / 細胞形態 / レスポンスガイドセラピー / 効果予測 / 静脈侵襲 / リンパ管侵襲 / リンパ節転移 / Progesterone receptor / Estrogen receptor / 無再発生存期間 / 無増悪生存期間 / Ki67標識率 / 腫瘍浸潤リンパ球 / エストロゲン受容体 / DORMANCY THERAPY / TAMOXIFEN / MDA-MB-231 TUMOR / APOPTOSIS / ANTIANGIOGENIC AGENT / 5-fluorouracil / Apoptosis / dormancy therapy / tamoxifen / MDA-MB-231腫瘍 / apoptosis / 微小血管密度 / Platelet derived endothelial cell growth factor / 接着因子 / micrometastasis / 生存期間 / 転移 / ラットDMBA乳腺腫瘍 / MCF-7 / platelet endothelial cell adhesion molecule-1 / vascular endothelial cell growth factor / platelet derived erdoihelial cell growth factor / fibronectin … More
Except Principal Investigator
外科 / 癌 / 電子デバイス・機器 / 磁性 / 計測工学 Less
  • Research Projects

    (6 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (16 People)
  •  A study on clinical implementation of response guided therapy with neoadjuvant endocrine therapy for breast cancer.Principal Investigator

    • Principal Investigator
      武井 寛幸
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Nippon Medical School
  •  New predictive markers of effectiveness of neoadjuvant endocrine therapy of breast cancer by analyzing tumor angiogenesisPrincipal Investigator

    • Principal Investigator
      Takei Hiroyuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Nippon Medical School
  •  Development of a magnetic probe for identifying the sentinel lymph node

    • Principal Investigator
      Sekino Masaki
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      The University of Tokyo
  •  SUPPRESSION OF TUMOR GROWTH BY ANTIANGIOGENIC AGENT AND INDUCTION TO TUMOR DORMANCY IN BREAST CANCERPrincipal Investigator

    • Principal Investigator
      HORIGUCHI Jun, 武井 寛幸
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      GUNMA UNIVERSITY FACULTY OF MEDICINE
  •  乳癌の微小転移予測とその治療に関する研究-血管新生からのアプローチ-Principal Investigator

    • Principal Investigator
      武井 寛幸
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General surgery
    • Research Institution
      Gunma University
  •  乳癌血管新生における接着因子に関する研究Principal Investigator

    • Principal Investigator
      武井 寛幸
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General surgery
    • Research Institution
      Gunma University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015

All Journal Article Presentation

  • [Journal Article] Cytomorphological Disparities in Invasive Breast Cancer Cells following Neoadjuvant Endocrine Therapy and Chemotherapy2024

    • Author(s)
      Hoshina Hideko、Sakatani Takashi、Kawamoto Yoko、Ohashi Ryuji、Takei Hiroyuki
    • Journal Title

      Pathobiology

      Volume: - Issue: 4 Pages: 1-11

    • DOI

      10.1159/000538227

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07218
  • [Journal Article] 術前薬物療法によりHER2過剰発現が陽性化した症例の検討2023

    • Author(s)
      山川珠実,武井寛幸,片山結美香,加藤世奈,小林光希,佐野恵美,范姜明志,栗田智子,坂谷貴司,大橋隆治
    • Journal Title

      乳癌基礎研究

      Volume: 32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07218
  • [Journal Article] Examining the effectiveness of a deep learning-based computer-aided breast cancer detection system for breast ultrasound2023

    • Author(s)
      Fujioka Tomoyuki、Kubota Kazunori、Hsu Jen Feng、Chang Ruey Feng、Sawada Terumasa、Ide Yoshimi、Taruno Kanae、Hankyo Meishi、Kurita Tomoko、Nakamura Seigo、Tateishi Ukihide、Takei Hiroyuki
    • Journal Title

      Journal of Medical Ultrasonics

      Volume: 50 Issue: 4 Pages: 511-520

    • DOI

      10.1007/s10396-023-01332-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07218
  • [Journal Article] Prognostic effect of subsequent childbirth after the diagnosis of breast cancer using propensity score matching analysis2023

    • Author(s)
      Ochi Tomohiro、Yoshida Atsushi、Takahashi Osamu、Kajiura Yuka、Takei Junko、Hayashi Naoki、Takei Hiroyuki、Yamauchi Hideko
    • Journal Title

      Breast Cancer

      Volume: 30 Issue: 3 Pages: 354-363

    • DOI

      10.1007/s12282-022-01429-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07218
  • [Journal Article] Use of Liquid Biopsy to Detect <i>PIK3CA</i> Mutation in Metastatic Breast Cancer2022

    • Author(s)
      Nakai Maki、Yamada Takeshi、Sekiya Kenta、Sato Ai、Hankyo Meishi、Kuriyama Sho、Takahashi Goro、Kurita Tomoko、Yanagihara Keiko、Yoshida Hiroshi、Ohashi Ryuji、Takei Hiroyuki
    • Journal Title

      Journal of Nippon Medical School

      Volume: 89 Issue: 1 Pages: 66-71

    • DOI

      10.1272/jnms.JNMS.2022_89-107

    • NAID

      130007996010

    • ISSN
      1345-4676, 1347-3409
    • Year and Date
      2022-02-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08583, KAKENHI-PROJECT-19K09160, KAKENHI-PROJECT-22K08811
  • [Journal Article] Optimal Treatment Duration of Neoadjuvant Endocrine Therapy for Women Aged 60 Years or Older with Estrogen Receptor-Positive, HER2-Negative Invasive Breast Cancer2021

    • Author(s)
      Hayashi Yuji、Takei Hiroyuki、Saito Tsuyoshi、Kai Toshihiro、Inoue Kenichi、Kurosumi Masafumi、Ninomiya Jun、Saitama Breast Cancer Clinical Study Group (SBCCSG)
    • Journal Title

      Journal of Nippon Medical School

      Volume: 88 Issue: 4 Pages: 354-360

    • DOI

      10.1272/jnms.JNMS.2021_88-509

    • NAID

      130008082565

    • ISSN
      1345-4676, 1347-3409
    • Year and Date
      2021-08-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08583
  • [Journal Article] Long Noncoding RNA HOXA11-AS and Transcription Factor HOXB13 Modulate the Expression of Bone Metastasis-Related Genes in Prostate Cancer2021

    • Author(s)
      Aya Misawa, Yukihiro Kondo, Hiroyuki Takei and Toshihiro Takizawa
    • Journal Title

      Genes

      Volume: 12(182) Issue: 2 Pages: 1-19

    • DOI

      10.3390/genes12020182

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09181, KAKENHI-PROJECT-18K08583, KAKENHI-PROJECT-20K09588
  • [Journal Article] Neoadjuvant Endocrine Therapy for Operable Breast Cancer: A Retrospective Analysis of Real-World Use2021

    • Author(s)
      Iwamoto Miki、Takei Hiroyuki、Ninomiya Jun、Asakawa Hideki、Kurita Tomoko、Yanagihara Keiko、Iida Shinya、Sakatani Takashi、Ohashi Ryuji
    • Journal Title

      Journal of Nippon Medical School

      Volume: 88 Issue: 5 Pages: 448-460

    • DOI

      10.1272/jnms.JNMS.2021_88-603

    • NAID

      130008117323

    • ISSN
      1345-4676, 1347-3409
    • Year and Date
      2021-10-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08583
  • [Journal Article] Capecitabine + Epirubicin + Cyclophosphamide Combination Therapy (CEX Therapy) as Neoadjuvant Chemotherapy for HER-2-Negative Breast Cancer: A Retrospective, Single-Center Study2020

    • Author(s)
      Yokoyama T, Makino H, Seki N, Ueda J, Hosone M, Katayama H, Takei H, Yoshida H.
    • Journal Title

      Journal of Nippon Medical School

      Volume: 87 Issue: 2 Pages: 73-79

    • DOI

      10.1272/jnms.JNMS.2020_87-204

    • NAID

      130007843307

    • ISSN
      1345-4676, 1347-3409
    • Year and Date
      2020-04-15
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08583
  • [Journal Article] Changes in Recurrence Score by neoadjuvant endocrine therapy of breast cancer and their prognostic implication2019

    • Author(s)
      Ueno Takayuki、Saji Shigehira、Masuda Norikazu、Iwata Hiroji、Kuroi Katsumasa、Sato Nobuaki、Takei Hiroyuki、Yamamoto Yutaka、Ohno Shinji、Yamashita Hiroko、Hisamatsu Kazufumi、Aogi Kenjiro、Sasano Hironobu、Toi Masakazu
    • Journal Title

      ESMO Open

      Volume: 4 Issue: 1 Pages: e000476-e000476

    • DOI

      10.1136/esmoopen-2018-000476

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08583, KAKENHI-PROJECT-15K10067, KAKENHI-PROJECT-19K09079
  • [Journal Article] Predictive and prognostic value of stromal tumour-infiltrating lymphocytes before and after neoadjuvant therapy in triple negative and HER2-positive breast cancer.2019

    • Author(s)
      Ochi T, Bianchini G, Ando M, Nozaki F, Kobayashi D, Criscitiello C, Curigliano G, Iwamoto T, Niikura N, Takei H, Yoshida A, Takei J, Suzuki K, Yamauchi H, Hayashi N.
    • Journal Title

      Eur J Cancer

      Volume: 118 Pages: 41-48

    • DOI

      10.1016/j.ejca.2019.05.014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08583
  • [Journal Article] Granulocyte-colony stimulating factor-associated aortitis in a woman with advanced breast cancer: a case report and review of the literature.2019

    • Author(s)
      Hoshina H, Takei H.
    • Journal Title

      BMC Cancer

      Volume: 19 Issue: 1 Pages: 1217-1217

    • DOI

      10.1186/s12885-019-6403-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08583
  • [Journal Article] Impact of clinical response to neoadjuvant endocrine therapy on patient outcome: a follow-up study of JFMC34-0601 multicentre prospective neoadjuvant endocrine trial.2018

    • Author(s)
      Ueno T, Saji S, Masuda N, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Iwata H, Yamanaka T, Sasano H, Toi M.
    • Journal Title

      ESMO Open.

      Volume: - Issue: 2 Pages: e000314-e000314

    • DOI

      10.1136/esmoopen-2017-000314

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10067, KAKENHI-PROJECT-15K10059, KAKENHI-PROJECT-18K08583
  • [Presentation] Cytomorphological disparities in invasive breast cancer cells following neoadjuvant endocrine therapy and chemotherapy.2024

    • Author(s)
      Hideko Hoshina, Takashi Sakatani, Yoko Kawamoto, Ryuji Ohashi, Hiroyuki Takei
    • Organizer
      第62回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07218
  • [Presentation] 術前内分泌療法により病理学的完全奏効が得られた乳癌の4症例2024

    • Author(s)
      小林光希、武井寛幸、栗田智子、中村卓、范姜明志、坂谷貴司、大橋隆治
    • Organizer
      第32回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07218
  • [Presentation] 術前薬物療法によりHER2発現が陽性化した症例の検討2022

    • Author(s)
      山川珠実,武井寛幸,片山結美香,加藤世奈,小林光希,佐野恵美,范姜明志,栗田智子,坂谷貴司,大橋隆治
    • Organizer
      第90回日本医科大学医学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07218
  • [Presentation] 乳癌のOncotypeDx再発スコアと臨床病理学的因子との関連性の検討2022

    • Author(s)
      八木 美緒, 田村 美樹, 小林 光希, 関谷 健太, 佐野 恵美, 范姜 明志, 栗田 智子, 坂谷 貴司, 大橋 隆治, 武井 寛幸
    • Organizer
      第30回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07218
  • [Presentation] 術前内分泌療法の新たな効果予測因子2020

    • Author(s)
      浅川 英輝、二宮 淳、坂谷 貴司、武井 寛幸
    • Organizer
      日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08583
  • [Presentation] Development of magnetic techniques for intraoperative diagnosis of breast cancer metastasis2017

    • Author(s)
      Sekino M, Kuwahata A, Kaneko M, Chikaki S, Tanabe N, Nakagawa T, Saeki K, Shiozawa M, Takei H, Nakamura S, Kusakabe M
    • Organizer
      Tsinghua-Todai Joint Workshop for Frontiers in Bioengineering and Biomedical Engineering
    • Place of Presentation
      北京(中国)
    • Year and Date
      2017-04-14
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25282129
  • [Presentation] センチネルリンパ節の探索に用いる永久磁石型磁気プローブの開発及び臨床評価2015

    • Author(s)
      大橋開智、大久保哲、塩澤幹雄、武井寛幸、中川貴之、斎藤逸郎、日下部守昭、関野正樹
    • Organizer
      第15回東京大学生命科学シンポジウム
    • Place of Presentation
      東京大学、東京都文京区
    • Year and Date
      2015-06-27
    • Data Source
      KAKENHI-PROJECT-25282129
  • [Presentation] 磁性粒子の医療への応用:新規磁気プローブ開発と磁性体を用いた乳癌センチネルリンパ節生検への応用2015

    • Author(s)
      日下部守昭、塩澤幹雄、大久保哲、中川貴之、佐伯亘平、武井寛幸、中村清吾、関野正樹
    • Organizer
      第17回Sentinel Node Navigation Surgery研究会学術集会
    • Place of Presentation
      ワークピア横浜、神奈川県横浜市
    • Year and Date
      2015-11-13
    • Data Source
      KAKENHI-PROJECT-25282129
  • 1.  HORIGUCHI Jun (70272242)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  坂谷 貴司 (50431903)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 3.  瀧澤 俊広 (90271220)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  栗田 智子 (70619204)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 5.  Sekino Masaki (20401036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  OHSAKI Hiroyuki (10203754)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  INOUE Yusuke (80611079)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KIM Dongmin (30638466)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KURABAYASHI Masahiko (00215047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  日下部 守昭 (60153277)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  中川 貴之 (40447363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  塩澤 幹雄 (20364515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  村上 隆介 (30267215)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  米戸 敏彦 (10837628)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  UENO Takayuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  三沢 彩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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