SHIBAGAKI Naotaka 柴垣直孝

Researcher Number	40262662
Other IDs
Affiliation (based on the past Project Information) *help	2016: 山梨大学, 総合研究部, 准教授 2014: 山梨大学, 総合研究部, 准教授 2011 – 2013: 山梨大学, 医学工学総合研究部, 准教授 2007 – 2011: University of Yamanashi, Dept of Research Interdisciplinary Graduate School of Medicine and Engineering, Associate Professor 2009: 山梨大学, 医学部附属病院, 講師 … More 2007: 山梨大学, 医学工学総合研究部, 准教授 2006: 山梨大学, 医学工学総合研究部, 助教授 2006: University of Yamanashi, Department of Research Interdisciplinary Graduate School of Medicine and Engineering, Associate Professor, 大学院医学工学総合研究部, 助教授 2003 – 2005: 山梨大学, 医学部附属病院, 講師 1997 – 1998: 山梨医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Dermatology / Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator ワクチン / Vaccine / TAT / 樹状細胞 / CD82 / メラノーマ / 悪性黒色腫 / 腫瘍免疫 / 皮膚腫瘍 / STAT3 … More / 癌免疫療法 / Protein transduction / Antigen presentation / Antigen-specific immune responses / タンパク抗原 / 免疫療法 / 細胞内タンパク導入 / 抗原提示 / 抗原特異的免疫反応 / Polyarginine / Protein Transduction / Tumor Immunity / Dendritic Cells / polyarginine / protein transduction / CANCER VACCINATION / CELL ADHESION / MELANOMA / 腫瘍ワクチン / 細胞接着 / トランスレーショナルリサーチ / 治療 / がん免疫 / 分指標的療法 / 分子標的療法 / タンパク導入 / STAT3阻害薬 / 癌ワクチン / 阻害薬 / 分子標的薬 / タンパク質細胞内導入 … More Except Principal Investigator 樹状細胞 / 免疫療法 / ランゲルハンス細胞 / Toll-like receptor / Herpes simplex virus / マスト細胞 / 自然免疫 / 抗菌ペプチド / HIV / HSV / 免疫抑制 / ギャップ結合 / 悪性黒色腫 / ワクチン / Acquired immunity / Innate immunity / Mast cell / 獲得免疫 / Connexin / Gap junction / Immunotherapy / Tumor immunity / Hybrid cells / Cell fusion / Macrophage / Dendritic cells / 癌免疫療法 / ハイブリド細胞 / コネキシン / 腫瘍免疫 / ハイブッリド細胞 / 融合細胞 / マクロファージ / ケラチノサイト / Alarmin / innate immunity / mast cell / herpes simplex virus / IL-33 / アラーミン / ヘルペスウイルス / 肥満細胞 / 性行為感染症 / 経皮感染 / 治療 / 癌遺伝子 / 分子標的療法 / 分子標的薬 / 腫瘍ワクチン / 抗炎症作用 / 角層剥離皮膚 / ペプチド / 細胞障害性T細胞 / 臨床試験 / 経皮免疫療法 / 悪性黒色種 Less

The alarmin IL-33 derived from HSV-2-infected keratinocytes triggers mast cell-mediated antiviral innate immunity
- Principal Investigator
  
  SHIMADA Shinji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
悪性黒色腫に対する新規ヒト型STAT3 特異的阻害薬による抗腫瘍効果の検討Principal Investigator
- Principal Investigator
  
  柴垣直孝
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
The elucidation of the early immune system in percutaneous infection of HSV and HIV and the development of novel methods to prevent their cutaneous infection
- Principal Investigator
  
  SHIMADA Shinji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
Analyses for the establishment of the effective immunotherapy to melanoma-bearing hostsPrincipal Investigator
- Principal Investigator
  
  SHIBAGAKI Naotaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
Novel therapeutic approach to melanoma-bearing hosts with protein-transduction technology
- Principal Investigator
  
  SHIMADA Shinji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
Novel therapeutic approach to skin diseases with protein-transduction technologyPrincipal Investigator
- Principal Investigator
  
  SHIBAGAKI Naotaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
Immunotherapy with percutaneous peptide immunization in human melanoma
- Principal Investigator
  
  TAKIGAWA Masahiro
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Dermatology
- Research Institution
  Hamamatsu University School of Medicine
免疫・炎症反応におけるギャップ結合の機能の解析及びギャップ結合阻害外用剤の開発
- Principal Investigator
  
  MATSUE Hiroyuki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Chiba University
Analyses for the enhancing methods of tumor vaccination therapy in cancer-bearing hostsPrincipal Investigator
- Principal Investigator
  
  SHIBAGAKI Naotaka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
Roles of mast cells on viral infection and mast cell-based immunotherapy
- Principal Investigator
  
  SHIMADA Shinji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
A new strategy for cancer immunotherapy using dendritic cell-macrophage hybrids
- Principal Investigator
  
  MATSUE Hiroyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
Analysis of Antitumor Immunity Using Dendritic Cells Treated with Various Protein-transduction Domain (PTD)-containing Protein AntigenPrincipal Investigator
- Principal Investigator
  
  SHIBAGAKI Naotaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  University of Yamanashi
Basic Analysis of Immuno-gene Therapy for Melanoma Using Functional Characteristic of CD82Principal Investigator
- Principal Investigator
  
  SHIBAGAKI Naotaka
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  YAMANASHI MEDICAL UNIVERSITY

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Case of primary cutaneous peripheral T-cell lymphoma, not otherwise specified, with characteristics of follicular helper T cells2014
- Author(s)
  Takaki M, Inozume T, Matsuzawa T, Ando N, Y amaguchi M, Harada K, Kawamura T, Shibagaki N, Shimada S
- Journal Title
  
  J Dermatol
  
  Volume: (In press) Issue: 6 Pages: 529-532
- DOI
  10.1111/1346-8138.12493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282, KAKENHI-PROJECT-23591614, KAKENHI-PROJECT-23591641
[Journal Article] A case of oral mucosal fixed eruption caused by methacrylate2014
- Author(s)
  Inozume T, Nakazawa R, Tanaka K, Harada K, Kawamura T, Shibagaki N, Shimada S
- Journal Title
  
  Contact Dermatitis
  
  Volume: 70(6) Issue: 6 Pages: 387-8
- DOI
  10.1111/cod.12183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282, KAKENHI-PROJECT-23591641
[Journal Article] Two cases of autosomal recessive woolly hair with LIPH gene mutations2013
- Author(s)
  Harada K, Inozume T, Kawamura T, Shibagaki N, Kinoshita T, Deguchi N, Shimada S
- Journal Title
  
  Int J Dermatol
  
  Volume: 52(5) Pages: 572-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282
[Journal Article] A case of dermatomyositis accompanied by spontaneous intramuscular hemorrhage despite normal coagulability2013
- Author(s)
  Hanawa F, Inozume T, Harada K, Andou N, Kawamura T, Shibagaki N, Shimada S
- Journal Title
  
  Rheumatol Int
  
  Volume: 33(11) Issue: 11 Pages: 2949-50
- DOI
  10.1007/s00296-012-2492-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282, KAKENHI-PROJECT-23591614, KAKENHI-PROJECT-23591641
[Journal Article] Case of rheumatoid papules : is this a link between vasculitis and rheumatoid nodules?2012
- Author(s)
  Inozume T, Ando N, Sano S, Harada K, Kawamura T, Shibagaki N, Shimada S
- Journal Title
  
  J Dermatol
  
  Volume: 39(12) Pages: 1091-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282
[Journal Article] Neutrophilic panniculitis with non-caseating granulomas in a Crohn's disease patient2012
- Author(s)
  Ogawa Y, Aoki R, Harada K, Matsuzawa T, Inozume T, Shibagaki N, Kawamura T, Shimada S
- Journal Title
  
  Eur J Dermatol
  
  Volume: 22(3) Issue: 3 Pages: 404-5
- DOI
  10.1684/ejd.2012.1737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282, KAKENHI-PROJECT-23591641
[Journal Article] Case of mucous membrane pemphigoid characterized by circulating immunoglobulin A and immunoglobulin G autoantibodies to the gamma-2 subunit of laminin-3322012
- Author(s)
  Hanawa F, Harada K, Andou N, Kawamura T, Shibagaki N, Fukuda S, Hashimoto T, Shimada S
- Journal Title
  
  J Dermatol
  
  Volume: 39(11) Pages: 962-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282
[Journal Article] 腫瘍免疫療法のトピックス2012
- Author(s)
  柴垣直孝
- Journal Title
  
  Skin Cancer
  
  Volume: 26巻 Pages: 267-273
- Data Source
  KAKENHI-PROJECT-23591613
[Journal Article] Gutter method : noninvasive management of ingrown nails caused by epidermal growth factor inhibitor treatment2012
- Author(s)
  Harada K, Y amaguchi M, Miyajima S, Kawamura T, Shibagaki S, Shimada S
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: 37(6) Pages: 703-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390282
[Journal Article] Novel Immunotherapeutic Approaches to Skin Cancer Treatments Using Protein T ransduction Technology. (Review)2011
- Author(s)
  N Shibagaki, et al.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 61(3) Pages: 153-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591316
[Journal Article] Protein-transduction domainを用いた抗原性の増強2011
- Author(s)
  柴垣直孝, ら
- Journal Title
  
  臨床免疫アレルギー科
  
  Volume: 55(3) Pages: 255-261
- Data Source
  KAKENHI-PROJECT-20591316
[Journal Article] Novel Immunotherapeutic Approaches to Skin Cancer Treatments Using Protein Transduction Technology.(Review)2011
- Author(s)
  N Shibagaki, et al.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 61(3) Pages: 153-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390306
[Journal Article] Protein-transduction domainを用いた抗原性の増強2011
- Author(s)
  柴垣直孝、島田眞路
- Journal Title
  
  臨床免疫アレルギー科 55巻
  
  Pages: 255-261
- Data Source
  KAKENHI-PROJECT-20390306
[Journal Article] Protein-transduction domainを用いた抗原性の増強2011
- Author(s)
  柴垣直孝、島田眞路
- Journal Title
  
  臨床免疫アレルギー科
  
  Volume: 55巻 Pages: 255-261
- Data Source
  KAKENHI-PROJECT-23591613
[Journal Article] Novel immunotherapeutic approaches to skin cancer treatments using protein transduction technology2011
- Author(s)
  N Shibagaki, Okamoto, H Mitsui, T.Inozume, M.kanzaki, S Shimada
- Journal Title
  
  Journal of Dermatological Science 61
  
  Pages: 153-161
- NAID
  10030890246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390306
[Journal Article] Novel Immunotherapeutic approaches to skin cancer treatments using protein transduction technology2011
- Author(s)
  NAOTAKA SHIBAGAKI
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 61巻 Issue: 3 Pages: 153-161
- DOI
  10.1016/j.jdermsci.2010.12.003
- NAID
  10030890246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591613
[Journal Article] Protein-transduction domainを用いた抗原性の増強2011
- Author(s)
  柴垣直孝, ら
- Journal Title
  
  臨床免疫アレルギー科
  
  Volume: 55(3) Pages: 255-261
- Data Source
  KAKENHI-PROJECT-20390306
[Journal Article] Novel immunotherapeutic approaches to skin cancer treatments using protein transduction technology2011
- Author(s)
  N Shibagaki, T Okamoto, H Mitsui, T Inozume, M kanzaki, S Shimada
- Journal Title
  
  Journal of Dermatological Science 61
  
  Pages: 153-161
- NAID
  10030890246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591316
[Journal Article] Protein-transduction domainを用いた抗原性の増強2011
- Author(s)
  柴垣直孝、島田眞路
- Journal Title
  
  臨床免疫アレルギー科 55巻
  
  Pages: 255-261
- Data Source
  KAKENHI-PROJECT-20591316
[Journal Article] Overexpression of GRIM-19 in cancer cells suppresses STAT3-mediated signal transduction and cancer growth2010
- Author(s)
  T.Okamoto, T.Inozume, H.Mitsui, M.kanzaki, K.Harada, N Shibagaki, S Shimada
- Journal Title
  
  Molecular Cancer Therapeutics 9
  
  Pages: 2333-2343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390306
[Journal Article] Overexpression of GRIM-19 in cancer cells suppresses STAT3-mediated signal transduction and cancer growth2010
- Author(s)
  T Okamoto, T Inozume, H Mitsui, M kanzaki, K Harada, N Shibagaki, S Shimada
- Journal Title
  
  Molecular Cancer Therapeutics 9
  
  Pages: 2333-2343
- Data Source
  KAKENHI-PROJECT-20591316
[Journal Article] A novel immunotherapeutic approach to melanoma-bearing mice hosts with protein-transduction domain containing immunogenic foreign antigens2010
- Author(s)
  M Kanzaki, T Okamoto, H Mitsui, N Shibagaki, S Shimada
- Journal Title
  
  Journal of Dermatological Science 60
  
  Pages: 84-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390306
[Journal Article] A novel immunotherapeutic approach to melanoma-bearing mice hosts with protein-transduction domain containing immunogenic foreign antigens2010
- Author(s)
  M Kanzaki, T Okamoto, H Mitsui, N Shibagaki, S Shimada
- Journal Title
  
  Journal of Dermatological Science 60
  
  Pages: 84-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591316
[Journal Article] Intradermal injiections of polyarginin-containing immunogenic antigens preferentially elicit Tc1 and Th1 activation and antitumor immunity2010
- Author(s)
  H.Mitsui, T.Okamoto, M.Kanzaki, T.Inozume, N Shibagaki, S Shimada
- Journal Title
  
  British Journal of Dermatology 162
  
  Pages: 29-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390306
[Journal Article] Intradermal injiections of polyarginin-containing immunogenic antigens preferentially elicit Tc1 and Th1 activation and antitumor immunity2010
- Author(s)
  H Mitsui, T Okamoto, M Kanzaki, T Inozume, N Shibagaki, S Shimada
- Journal Title
  
  British Journal of Dermatology 162
  
  Pages: 29-41
- Data Source
  KAKENHI-PROJECT-20591316
[Journal Article] 抗原ペプチドの樹状細胞への遺伝子導入法と免疫原性2009
- Author(s)
  柴垣直孝
- Journal Title
  
  臨床免疫アレルギー科 51
  
  Pages: 586-594
- Data Source
  KAKENHI-PROJECT-20591316
[Journal Article] 抗原ペプチドの樹状細胞への遺伝子導入法と免疫原性2009
- Author(s)
  柴垣直孝
- Journal Title
  
  臨床免疫アレルギー科 51
  
  Pages: 586-594
- Data Source
  KAKENHI-PROJECT-20390306
[Journal Article] 抗原ペプチドの樹状細胞への遺伝子導入法と免疫原性2009
- Author(s)
  柴垣直孝
- Journal Title
  
  臨床免疫アレルギー科 51
  
  Pages: 586-594
- Data Source
  KAKENHI-PROJECT-20591316
[Journal Article] Human eosinophils have an intact Smad signaling pathway leading to a major transforming growth factor-β target gene expression.2007
- Author(s)
  Kanzaki, M., Shibagaki, N., Hatsushika, K., Mitsui, H., Inozume, T., Okamoto, A., Dobashi, Y., Ogawa, H., Shimada, S., Nakao, A.
- Journal Title
  
  Int Arch Allergy Immunol 142
  
  Pages: 309-317
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390310
[Journal Article] Human eosinophils have an intact signaling pathway leading to a major transforming growth factor-beta target gene expression.2007
- Author(s)
  M. Kanzaki, N. Shibagaki, et. al.
- Journal Title
  
  International Archives of Allergy and Immunology 142
  
  Pages: 309-317
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591241
[Journal Article] Dendritic cells transduced with autoantigen FCRLA induce cytotoxic lymphocytes and vaccinate against murine B-cell lymphoma.2007
- Author(s)
  T. Inozume, N. Shibagaki, et. al.
- Journal Title
  
  Journal of Investigative Dermatology 127
  
  Pages: 2818-2822
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591241
[Journal Article] Dendritic cells transduced with autoantigen FCRLA induce cytotoxic lymphocytes and vaccinate against murine B-cell lymphoma2007
- Author(s)
  T. Inozume, N. Shibagaki, et. al.
- Journal Title
  
  Journal of Investigative Dermatology 127
  
  Pages: 2818-2822
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591241
[Journal Article] Human eosinophils have an intact signaling pathway leading to a major transforming growth factor-beta target gene expression2007
- Author(s)
  M. Kanzaki, N. Shibagaki, et. al.
- Journal Title
  
  International Archives of Allergy and Immunology 142(4)
  
  Pages: 309-317
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591241
[Journal Article] CD4^+ CD25^<high> regulatory T cells are markedly decreased in blood of patients with pemphigus vulgaris.2007
- Author(s)
  Sugiyama, H., Matsue, H., Nagasaka, A., Nakamura, Y., Tsukamoto, K., Shibagaki, N., Kawamura, T., Kitamura, R., Ando, N., Shimada, S.
- Journal Title
  
  Dermatology 214
  
  Pages: 210-220
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390310
[Journal Article] Polyarginine-mediated protein delivery to dendritic cells presents antigen more efficiently onto MHC class I and class II and elicits superior antitumor immunity.2006
- Author(s)
  H. Mitsui, N. Shibagaki, et. al.
- Journal Title
  
  Journal of Investigative Dermatology 126
  
  Pages: 1804-1812
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591241
[Journal Article] Polyarginine-mediated protein delivery to dendritic cells presents antigen more efficiently onto MHC class I and class II2006
- Author(s)
  Mitsui H, Inozume T, Kitamura R, Shibagaki N, shimada S.
- Journal Title
  
  Jouranal of Investigative Dermatology 126(8)
  
  Pages: 1804-12
- Data Source
  KAKENHI-PROJECT-18591241
[Journal Article] Human eosinophils have an intact Smad signaling pathway leading to a major transforming growth factor-beta traget gene expression2006
- Author(s)
  Kanzaki M, Shibagaki N, Hatsushika K, Mitsui H, Inozume T Okamoto A, Dobashi Y, Ogawa H, Shimada S, Nkao A.
- Journal Title
  
  International Archive of Allegy and Immunology 142(4)
  
  Pages: 309-17
- Data Source
  KAKENHI-PROJECT-18591241
[Journal Article] Polyarginine-mediated protein delivery to dendritic cells presents antigen more efficiently onto MHC class I and class II and elicits superior antitumor immunity2006
- Author(s)
  H. Mitsui, N.Shibagaki, et. al.
- Journal Title
  
  Journal of Investigative Dermatology 126(1)
  
  Pages: 1804-1812
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591241
[Journal Article] Polyarginine-mediated protein delivery to dendritic cells presents antigen more efficiently onto MHC class I and class II and elicits superior antitumor immunity.2006
- Author(s)
  Mitsui, H., Inozume, T., Kitamura, R., Shibagaki, N., Shimada, S.
- Journal Title
  
  J Invest Dermatol 126
  
  Pages: 1804-1812
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390310
[Journal Article] Intradermal Injection of Polyarginine-containing Immunogenic Antigens Preferentially Elicit Tel and Thl Activation and Antitumor Immunity
- Author(s)
  Mitsui H., Okamoto T., Kanzaki M., Inozume T., Shibagaki N., Shimada S.
- Journal Title
  
  British Journal of Dermatology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390306
[Journal Article] Intradermal Injection of Polyarginine-containing Immunogenic Antigens Preferentially Elicit Tc1 and Th1 Activation and Antitumor Immunity
- Author(s)
  Mitsui H., Okamoto T., Kanzaki M., Inozume T., Shibagaki N., Shimada S.
- Journal Title
  
  British Journal of Dermatology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591316
[Presentation] Complete B16 melanoma regression with melanoma-specific CTL expansion is elicited simply by intratumoral injections of rR9-GRIM19 plus Th1/Tc1-inducible adjuvants.2013
- Author(s)
  Naotaka Shibagaki
- Organizer
  8th World Congress of Melanoma (World melanoma 2013)
- Place of Presentation
  Congress Center Hamburg（ドイツ　ハンブルグ）
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] 最新の皮膚医学研究;STAT3に対する新規分子標的阻害薬の開発とその抗腫瘍効果の解析2013
- Author(s)
  柴垣直孝
- Organizer
  第112回日本皮膚科学会総会学術大会
- Place of Presentation
  横浜市
- Year and Date
  2013-06-26
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] Complete B16 melanoma regression with melanoma-specific CTL expansion is elicited simply by intratumoral injections of rR9-GRIM19 plus Th1/Tc1-inducible adjuvants2013
- Author(s)
  Naotaka Shibagaki
- Organizer
  8^<th> World Congress of Melanoma (World melanoma 2013)
- Place of Presentation
  ドイツハンブルグ
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] STAT3に対する新規分子標的阻害薬の開発とその抗腫瘍効果の解析2013
- Author(s)
  柴垣直孝
- Organizer
  第１１２回日本皮膚科学会総会　学術大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] がん微小環境における免疫抑制状態の機序2013
- Author(s)
  柴垣直孝
- Organizer
  第29回皮膚悪性腫瘍学会総会
- Place of Presentation
  甲府市
- Year and Date
  2013-08-09
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] IL-6 produced from B16 melanoma cells activates STAT3 in all CD4+ and CD8+ T cells with suppressing the IFN-gamma-producing potential2013
- Author(s)
  柴垣直孝
- Organizer
  第17回日本がん免疫学会総会
- Place of Presentation
  宇部市
- Year and Date
  2013-07-04
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] がん微小環境における免疫抑制状態の機序2013
- Author(s)
  柴垣直孝
- Organizer
  第２９回皮膚悪性腫瘍学会総会
- Place of Presentation
  甲府富士屋ホテル（山梨県甲府市）
- Invited
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] Complete cutaneous B-cell lymphoma regression following intratumoral injections of a novel STAT3-inhibitor (rR9-GRIM19) alone is elicited via rapid CD8+ and CD4+ T cell conversion of IL-10-producing into IL-17/ IFN-gamma-producing phenotypes.2012
- Author(s)
  柴垣直孝
- Organizer
  第４２回ヨーロッパ研究皮膚科学会総会
- Place of Presentation
  Lido Casino (イタリア　ベニス)
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] A20 tumor regression by rR9-GRIM19 is elicited via T cell conversion of IL-10 into IL-17/ IFN-gamma-producing phenotypes.2012
- Author(s)
  柴垣直孝
- Organizer
  第１６回日本がん免疫学会総会
- Place of Presentation
  北海道大学学術交流会館（札幌）
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] A20 tumor regression by rR9-GRIM19 is elicited via both CD8+ and CD4+T cell conversion of IL-10 into IL-17/IFN-gamma-producing phenotypes2012
- Author(s)
  花輪書絵、柴垣直孝
- Organizer
  第37回日本研究皮膚科学会総会
- Place of Presentation
  那覇市
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] B-cell lymphoma regression following intratumoral injections of a novel STAT3-inhibitor (rR9-GRIM19) alone is elicited via both CD8+ and CD4+ T cell conversion of IL-10-producing into IL-17/ IFN-gamma producing phenotypes2012
- Author(s)
  柴垣直孝
- Organizer
  第４１回日本免疫学会総会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] Complete cutaneous B-cell lymphoma regression following intratumoral injections of a novel STAT3-inhibitor (rR9-GRIM19) alone is elicited via rapid CD8+ and CD4+ T cell conversion of IL-10-producing into IL-17/IFN-gamma-producing phenotypes2012
- Author(s)
  柴垣直孝
- Organizer
  第42回ヨーロッパ研究皮膚科学会総会
- Place of Presentation
  イタリアベニス
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] A20 tumor regression by rR9-GRIM19 is elicited via T cell conversion of IL-10 into IL-17/IFN-gamma-producing phenotypes2012
- Author(s)
  柴垣直孝
- Organizer
  第16回日本がん免疫学会総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] B cell lymphoma regression following intratumoral injections of a novel STAT3-inhibitor (rR9-GRIM19) alone is ekicited via both CD8+ and CD4+ T cell conversion of IL-10-producing into IL-17/IFN-gamma-producing phenotypes2012
- Author(s)
  柴垣直孝
- Organizer
  第41回日本免疫学会総会
- Place of Presentation
  神戸市
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] A novel STAT3 inhibitor (rR9-GRIM19) ....2011
- Author(s)
  Takashi Okamoto, Naotaka Shibagaki, et al.
- Organizer
  Society for Investigative Dermatology
- Place of Presentation
  JW Marriott Hotel (アメリカ合衆国アリゾナ州フェニックス)
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] 癌免疫療法のトピックスと展望2011
- Author(s)
  柴垣直孝
- Organizer
  第74回日本皮膚科学会東京支部学術大会
- Place of Presentation
  東京(お台場)
- Year and Date
  2011-02-12
- Data Source
  KAKENHI-PROJECT-20390306
[Presentation] 腫瘍免疫療法のトピックスー治療効果を向上させるためにはー2011
- Author(s)
  柴垣直孝
- Organizer
  第27回日本皮膚悪性腫瘍学会総会
- Place of Presentation
  新宿
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] CTL-mediated complete B16-melanoma ....2011
- Author(s)
  Fumie Hanawa, Naotaka Shibagaki, et al.
- Organizer
  第３６回日本研究皮膚科学会総会
- Place of Presentation
  京都国際会議場（京都）
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] Complete A20-tumor rejection by intratumoral injections of a novel STAT3-inhibitor (rR9-GRIM19) alone is elicited via rapid CD8+ and CD4+ T cell conversion of IL-10-producing into IL-17/IFN-gamma-producing phenotypes2011
- Author(s)
  Naotaka Shibagaki
- Organizer
  第15回日本がん免疫学会総会
- Place of Presentation
  大阪市
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] 癌免疫療法のトピックスと展望2011
- Author(s)
  柴垣直孝
- Organizer
  第74回日本皮膚科学会東京支部学会
- Place of Presentation
  東京
- Year and Date
  2011-02-12
- Data Source
  KAKENHI-PROJECT-20591316
[Presentation] 癌免疫療法のトピックスと展望2011
- Author(s)
  柴垣直孝
- Organizer
  第74回日本皮膚科学会東京支部学術大会
- Place of Presentation
  東京(お台場)
- Year and Date
  2011-02-12
- Data Source
  KAKENHI-PROJECT-20591316
[Presentation] 腫瘍免疫療法のトピックス -治療効果を向上させるためには-2011
- Author(s)
  柴垣直孝
- Organizer
  第２７回日本皮膚悪性腫瘍学会総会(招待講演)
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] 癌免疫療法のトピックスと展望2011
- Author(s)
  柴垣直孝
- Organizer
  第74回日本皮膚科学会東京支部学会
- Place of Presentation
  東京
- Year and Date
  2011-02-12
- Data Source
  KAKENHI-PROJECT-20390306
[Presentation] CTL-mediated complete B16-melanoma rejection was elicited only by the combination therapy with STAT3-inhibitor plus Th1-inducer stimulations2011
- Author(s)
  花輪書絵、柴垣直孝
- Organizer
  第36回日本研究皮膚科学会総会
- Place of Presentation
  京都市
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] Complete A20-tumor rejections by intratumoral.....2011
- Author(s)
  Naotaka Shibagaki
- Organizer
  第１５回日本がん免疫学会総会
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Data Source
  KAKENHI-PROJECT-23591613
[Presentation] Intratumoral injections of a novel STAT3 inhibitor (R9-GRIM19)enhance antitumor effects combined with cancer immunotherapy in melanoma-bearing mice2010
- Author(s)
  岡本崇、柴垣直孝、島田眞路
- Organizer
  第35回に本研究皮膚科学会
- Place of Presentation
  和歌山
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-20591316
[Presentation] 腫瘍免疫療法の新たな展望2010
- Author(s)
  柴垣直孝
- Organizer
  第109回日本皮膚科学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-20390306
[Presentation] 腫瘍免疫療法の新たな展望2010
- Author(s)
  柴垣直孝
- Organizer
  第109回日本皮膚科学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-20591316
[Presentation] 腫瘍免疫療法の新たな展望(教育講演)2010
- Author(s)
  柴垣直孝
- Organizer
  第109回日本皮膚科学会総会学術大会
- Place of Presentation
  大阪(中之島)
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-20390306
[Presentation] Intratumoral injections of a novel STAT3 inhibitor (R9-GRIM19)enhance antitumor effects combined with cancer immunotherapy in melanoma-bearing mice2010
- Author(s)
  岡本崇、柴垣直孝、島田眞路
- Organizer
  第35回に本研究皮膚科学会
- Place of Presentation
  和歌山
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-20390306
[Presentation] 腫瘍免疫療法の新たな展望(教育講演)2010
- Author(s)
  柴垣直孝
- Organizer
  第109回日本皮膚科学会総会学術大会
- Place of Presentation
  大阪(中之島)
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-20591316
[Presentation] Overexpression of GRIM19 in cancer cells suppresses STAT3-mediated signal transduction and cancer growth2009
- Author(s)
  Naotaka Shibagaki
- Organizer
  World Congress of Inflammation 2009
- Place of Presentation
  東京都新宿
- Year and Date
  2009-07-08
- Data Source
  KAKENHI-PROJECT-20591316
[Presentation] Overexpression of GRIM19 in cancer cells suppresses STAT3-mediated signal transduction and cancer growth2009
- Author(s)
  柴垣直孝
- Organizer
  World Congress of Inflammation 2009
- Place of Presentation
  東京
- Year and Date
  2009-07-08
- Data Source
  KAKENHI-PROJECT-20390306
[Presentation] Overexpression of GRIM19 in cancer cells suppresses STAT3-mediated signal transduction and cancer growth2009
- Author(s)
  柴垣直孝
- Organizer
  World Congress of Inflammation 2009
- Place of Presentation
  東京
- Year and Date
  2009-07-08
- Data Source
  KAKENHI-PROJECT-20591316
[Presentation] A Novel Immunotherapeutic Approach to Cancer-bearing Host with Protein-transduction Domain-containing Immunogenic Foreign Antigens2009
- Author(s)
  Shibagaki N, et al.
- Organizer
  International Society for Investigative Dermatology
- Place of Presentation
  Kyoto
- Year and Date
  2009-05-17
- Data Source
  KAKENHI-PROJECT-20390306
[Presentation] A novel immunotherapeutic approach to cancer-bearing host with protein-transduction domain-containing immunogenic foreign antigens2008
- Author(s)
  柴垣直孝
- Organizer
  International Investigative Dermatology 2008
- Place of Presentation
  京都
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20390306
[Presentation] A novel immunotherapeutic approach to cancer-bearing host with protein-transduction domain-containing immunogenic foreign antigens2008
- Author(s)
  柴垣直孝
- Organizer
  International Investigative Dermatology 2008
- Place of Presentation
  京都
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20591316
[Presentation] A Novel Vaccination System Utilizing Protein-transduction Domain2007
- Author(s)
  N. Shibagaki
- Organizer
  World Congress of Dermatology
- Place of Presentation
  Buenos Aires. (Argentine)
- Year and Date
  2007-10-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591241
[Presentation] A Novel Vaccination System Utilizing Protein-transduction Domain2007
- Author(s)
  N. Shibagaki
- Organizer
  World Congress of Dermatology
- Place of Presentation
  Buenos Aires(Argentine)
- Year and Date
  2007-10-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591241
[Presentation] Anti-B16 melanoma effects via rR9-GRIM19 are strongly enhanced by co-treatment with recombinant Interferons in vitro and in vivo
- Author(s)
  T. Okamoto, N. Shibagaki, S. Shimada.
- Organizer
  第３９回日本研究皮膚科学会学術大会
- Place of Presentation
  大阪市　ホテル阪急エキスポパーク
- Year and Date
  2014-12-12 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-26461682

1. SHIMADA Shinji (10114505)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
2. KAWAMURA Tatsuyoshi (70262657)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. MATSUE Hiroyuki (10250424)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. HARADA Kazutoshi (20324197)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
5. HASHIZUME Hideo (50237921)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YAGI Hiroaki (20242779)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ITO Taisuke (90293638)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SEO Naohiro (50283354)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TAKIGAWA Masahiro (80115873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TOKURA Yoshiki (00172156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHIMAUCHI Takatoshi (90399204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHIBAKI Akihiko (40291231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. INOZUME Takashi (80334853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HANAWA Fumie (80535592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. HAMADA Hirofumi (00189614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAGASAKA Akiko (60377546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. AOKI Rui (10377541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NISHIYAMA Hiroyuki (60115615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 堀部尚弘 (10306277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 神戸直智 (50335254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 姚建 (50303128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIBAGAKI Naotaka 柴垣 直孝

Research Projects

Research Products

Co-Researchers

The alarmin IL-33 derived from HSV-2-infected keratinocytes triggers mast cell-mediated antiviral innate immunity

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悪性黒色腫に対する新規ヒト型STAT3 特異的阻害薬による抗腫瘍効果の検討Principal Investigator

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The elucidation of the early immune system in percutaneous infection of HSV and HIV and the development of novel methods to prevent their cutaneous infection

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Analyses for the establishment of the effective immunotherapy to melanoma-bearing hostsPrincipal Investigator

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Novel therapeutic approach to melanoma-bearing hosts with protein-transduction technology

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Novel therapeutic approach to skin diseases with protein-transduction technologyPrincipal Investigator

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Immunotherapy with percutaneous peptide immunization in human melanoma

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免疫・炎症反応におけるギャップ結合の機能の解析及びギャップ結合阻害外用剤の開発

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Analyses for the enhancing methods of tumor vaccination therapy in cancer-bearing hostsPrincipal Investigator

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Roles of mast cells on viral infection and mast cell-based immunotherapy

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A new strategy for cancer immunotherapy using dendritic cell-macrophage hybrids

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Analysis of Antitumor Immunity Using Dendritic Cells Treated with Various Protein-transduction Domain (PTD)-containing Protein AntigenPrincipal Investigator

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Basic Analysis of Immuno-gene Therapy for Melanoma Using Functional Characteristic of CD82Principal Investigator

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SHIBAGAKI Naotaka 柴垣直孝