OSADA SHIGEHIRO 長田茂宏

… Alternative Names

Osada Shigehiro 長田茂宏

OSADA Shigehiro 長田茂宏

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Researcher Number	40263305
Other IDs
Affiliation (Current)	2025: 和歌山県立医科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 和歌山県立医科大学, 薬学部, 教授 2020: 第一薬科大学, 薬学部, 教授 2016 – 2017: 名古屋市立大学, 大学院薬学研究科, 准教授 2011 – 2015: 名古屋市立大学, 薬学研究科(研究院), 准教授 2007 – 2010: Nagoya City University, Graduate School of Pharmaceutical Sciences, Department of Molecular Biology, Associate Professor … More 2005 – 2006: 名古屋市立大学, 大学院薬学研究科, 助教授 2004: 大阪大学, 大学院・薬学研究科, 助手 2002 – 2003: 大阪大学, 薬学研究科, 助手 1998: 大阪大学, 薬学研究科, 助手 1996 – 1997: Osaka University, School of Pharmaceutical Sciences, Research associate, 薬学部, 助手 1995: 福井大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological Sciences / Biological pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Science and Engineering Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / 環境保全
Keywords	Principal Investigator エピジェネティクス / ヒストン / クロマチン / 腫瘍マーカー / ヒストンバリアント / メチル化 / アセチル化 / ヒストンアセチル化酵素 / 細胞がん化 / がん … More / 遺伝子発現制御 / 脱アセチル化 / 発がん / サイレンシング / クロマチン形成因子 / 化学発がん / GST-P / サイレンサー / シスエレメント / 転写調節因子 / 遺伝子発現調節 / 脱アセチル化酵素 / メチル化酵素 / tumor marker / carcinogenesis / gene expression / histone variant / acetylation / epignetics / histone / chromatin / 前がん病変 / ヒストン修飾 / ヒストンメチル化 / ヒストンアセチル化 / アルギニンメチル化酵素 / ヒストン脱アセチル化酵素 / ヒストン修飾酵素 / 発がん防御 / GSTP / DNAマイクロアレイ / 肝前がん病変 / グルタチオントランスフェラーゼ / GSTP1-1 / DNAメチル化酵素 / 核内ホルモン受容体 / 有機スズ化合物 / 環境ホルモン / 内分泌攪乱物質 / nuclear factor 1 / DNA結合 / 転写抑制因子 / NF1 / EBP / C / 転写不活性化因子 … More Except Principal Investigator 胆汁うっ滞肝障害 / 胆汁うっ滞肝毒性 / トランスポーター / 小腸細胞 / MPS / 灌流 / 毛細胆管 / 胆汁うっ滞肝毒性評価系 / 肝細胞 / facultative anaerobe / acid tolerant bacteria / ammonium production / nitrate reduction / neutralization mechanism / soil bacteria / acidification / アンモニア産生菌 / 硝酸還元菌 / 弱酸性耐性 / 酸性雨 / 通性嫌気性菌 / 酸性耐性菌 / アンモニア産生 / 硝酸還元 / 中和機構 / 土壌細菌 / 土壌酸性化 Less

灌流型小腸-肝臓2臓器連結デバイスを用いた胆汁鬱滞肝毒性評価系の展開
- Principal Investigator
  
  堺陽子
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Wakayama Medical University
Functional elucidation and basic research for drug discovery of histone modification enzymes involved in early stages of carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Osada Shigehiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Wakayama Medical University
  Daiichi University, College of Pharmaceutical Sciences
Regulation of cell death by epigenetics regulatory factors upregulated during the early stages of hepatocarcinogenesisPrincipal Investigator
- Principal Investigator
  
  Osada Shigehiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
Roles epigenetics regulatory factors induced hepatocarcinogenesis in malignant transformation and defense against cancer.Principal Investigator
- Principal Investigator
  
  OSADA Shigehiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
Analysis of the functional interactions of factors concerned with histones in malignant transformation.Principal Investigator
- Principal Investigator
  
  OSADA Shigehiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
Functional analysis epigenetics regulators in carcinogenesisPrincipal Investigator
- Principal Investigator
  
  OSADA Shigehiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
クロマチン形成因子とヒストン修飾酵素のクロストークの解明Principal Investigator
- Principal Investigator
  
  長田茂宏
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya City University
腫瘍マーカー陽性単一細胞を用いた細胞がん化と防御の分子機構の解明Principal Investigator
- Principal Investigator
  
  長田茂宏
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
エピジェネティクス制御因子の生物学的役割の解明とがん化との関連Principal Investigator
- Principal Investigator
  
  長田茂宏
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagoya City University
  Osaka University
内分泌攪乱物質のクロマチン修飾酵素複合体に対する影響Principal Investigator
- Principal Investigator
  
  長田茂宏
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
腫瘍マーカー遺伝子の発現を負に制御する因子の解析Principal Investigator
- Principal Investigator
  
  長田茂宏
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
ダルタチオントランスフェラーゼP遺伝子の発現を負に制御する因子の解析Principal Investigator
- Principal Investigator
  
  長田茂宏
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
Acid tolerant soil bacteria which reduce nitrate to produce ammonium under facultative anaerobic condition
- Principal Investigator
  
  NISHIHARA Tsutomu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境保全
- Research Institution
  Osaka University

[Book] 第7章がんと転写因子、がん増殖と悪性化の分子機構(宮澤恵二・伊東進編)2012
- Author(s)
  長田茂宏
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23590085
[Book] 第７章　がんと転写因子　「がん増殖と悪性化の分子機構」（宮澤恵二・伊東進　編）2012
- Author(s)
  長田茂宏
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-23590085
[Journal Article] 発がん初期に発現上昇するヒストン修飾酵素の役割2017
- Author(s)
  長田茂宏
- Journal Title
  
  細胞
  
  Volume: 49 Pages: 412-415
- Data Source
  KAKENHI-PROJECT-26460072
[Journal Article] Elevated expression of coactivator-associated arginine methyltransferase 1 is associated with early hepatocarcinogenesis2013
- Author(s)
  Osada, S., Suzuki, S., Yoshimi, C., Matsumoto, M., Shirai, T., Takahashi, S., and Imagawa, M
- Journal Title
  
  Oncol. Rep
  
  Volume: Vol. 30, No. 4 Pages: 1669-1674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590085
[Journal Article] Elevated expression of coactivator-associated arginine methyltransferase 1 is associated with early hepatocarcinogenesis.2013
- Author(s)
  Osada, S., Suzuki, S., Yoshimi, C., Matsumoto, M., Shirai, T., Takahashi, S., Imagawa, M.
- Journal Title
  
  Oncol Rep.
  
  Volume: 30 Issue: 4 Pages: 1669-1674
- DOI
  10.3892/or.2013.2651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590085
[Journal Article] Inositol phosphate kinase Vip1p interacts with histone chaperone Asf1p in Saccharomyces cerevisiae2012
- Author(s)
  Osada, S., Kageyama, K., Ohnishi, Y., Nishikawa, J., Nishihara, T., and Imagawa, M
- Journal Title
  
  Mol. Biol. Rep
  
  Volume: Vol. 39, No. 4 Pages: 4989-4996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590085
[Journal Article] Inositol phosphate kinase Vip 1p interacts with histone chaperone Asf1p in Saccharomyces cerevisiae2012
- Author(s)
  Osada S.
- Journal Title
  
  Mol.Biol.Rep.
  
  Volume: 39 Issue: 4 Pages: 4989-4996
- DOI
  10.1007/s11033-011-1295-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590143, KAKENHI-PROJECT-23590085
[Journal Article] Histone methyltransferase PR-Set7 and histone variant H2A.Z, induced during hepatocarcinogenesis, repress the promoter activity of the tumor marker gene and the ras-induced colony formation activity.2011
- Author(s)
  Hashizume, H., Gomita, U., Imagawa, M., Osada, S.
- Journal Title
  
  J.Health Sci. in press
- NAID
  130000800087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590065
[Journal Article] Promotion of anchorage-independent growth by cytoplasmic and nuclear histone deacetylase 9.2010
- Author(s)
  Yura, T., Hashizume, H., Suzuki, E., Imagawa, M., Osada, S.
- Journal Title
  
  J.Health Sci. 50
  
  Pages: 581-588
- NAID
  130000425094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590065
[Journal Article] Toxicity of nickel compounds mediated by HTZI, histone variant H2A. Z, in Saccharomyces cerevisiae.2008
- Author(s)
  Shigehiro Osada
- Journal Title
  
  Biol. Pharm. Bull 31
  
  Pages: 2007-2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590065
[Journal Article] Toxicity of nickel compounds mediated by HTZ1, histone variant H2A.Z, in Saccharomyces cerevisiae.2008
- Author(s)
  Gomita, U., Imagawa, M., Osada, S.
- Journal Title
  
  Biol Pharm Bull. 31
  
  Pages: 2007-2011
- NAID
  110006968078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590065
[Journal Article] Histone modification enzymes induced during chemical hepatocarcinogenesis.2007
- Author(s)
  Shigehiro Osada
- Journal Title
  
  Yakugaku Zasshi 127・3
  
  Pages: 469-479
- NAID
  110006240156
- Data Source
  KAKENHI-PROJECT-18590066
[Journal Article] Histone modification enzymes induced during chemical hepatocarcinogenesis2007
- Author(s)
  Shigehiro, Osada
- Journal Title
  
  Yakugaku Zasshi 127
  
  Pages: 469-479
- NAID
  110006240156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590066
[Journal Article] Altered gene expression of transcriptional regulatory factors in tumor marker-positive cells during chemically induced hepatocarcinogenes2006
- Author(s)
  Shigehiro Osada
- Journal Title
  
  Toxicology letters 167・2
  
  Pages: 106-113
- Data Source
  KAKENHI-PROJECT-18590066
[Journal Article] Altered gene expression of transcriptional regulatory factors in tumor marker-positive cells during chemically induced hepatocarcinogenes2006
- Author(s)
  Shigehiro Osada
- Journal Title
  
  Toxicology Letters 167
  
  Pages: 106-113
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590066
[Journal Article] Altered gene expression of transcriptional regulatory factors in tumor marker-positive cells during chemically induced hepatocarcinogenes2006
- Author(s)
  Shigehiro, Osada
- Journal Title
  
  Toxicology Letters 167
  
  Pages: 106-113
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590066
[Journal Article] Chromatin assembly factor Asf1p-dependent occupancy of the SAS histone acetyltransferase complex at the silent mating-type locus HMLα2005
- Author(s)
  Osada, S., Kurita, M., Nishikawa, J., Nishihara, T.
- Journal Title
  
  Nucl.Acids Res. 33巻・8号
  
  Pages: 2742-2750
- Data Source
  KAKENHI-PROJECT-16790053
[Journal Article] Nuclear factor 1 family members interact with hepatocyte nuclear factor 1α to synergistically activate L-type pyruvate kinase gene transcription.2005
- Author(s)
  Satoh, S., Noaki, T., Ishigure, T., Osada, S., Imagawa, M., Miura, N., Yamada, K., Noguchi, T.
- Journal Title
  
  J.Biol.Chem. 280巻48号
  
  Pages: 39827-39834
- Data Source
  KAKENHI-PROJECT-16790053
[Journal Article] Selective induction of a tumor marker glutathione S-transferase P1 by proteasome inhibitors.2005
- Author(s)
  Usami, H., Kusano, Y., Kumagai, T., Osada, S., Itoh, K., Kobayashi, A., Yamamoto, M., Uchida, K.
- Journal Title
  
  J.Biol.Chem. 280巻26号
  
  Pages: 25267-25276
- Data Source
  KAKENHI-PROJECT-16790053
[Journal Article] Chromatin assembly factor Asf1p-dependent occupancy of the SAS histone acetyltransferase complex at the silent mating-type locus HMLα2005
- Author(s)
  Osada, S., Kurita, M., Nishikawa, J., Nishihara, T.
- Journal Title
  
  Nucl.Acids Res. 33巻・8号
  
  Pages: 2742-2750
- Data Source
  KAKENHI-PROJECT-17054023
[Journal Article] Cloning and characterization of a cDNA encoding the histone acetyltransferase monocytic leukemia zinc finger protein (MOZ) in rat
- Author(s)
  Ohta, K., Osada, S., Nishikawa, J., Nishihara, T.
- Journal Title
  
  Journal of Health Science (in press)
- NAID
  10016657276
- Data Source
  KAKENHI-PROJECT-16021232
[Journal Article] Cloning and characterization of a cDNA encoding the histone acetyl transferase monocytic leukemia zinc finger protein (MOZ) in rat
- Author(s)
  Ohta, K., Osada, S., Nishikawa, J., Nishihara, T.
- Journal Title
  
  Journal of Health Science (in press)(印刷中)
- NAID
  10016657276
- Data Source
  KAKENHI-PROJECT-16790053
[Journal Article] Organization of gene structure and expression of nuclear factor 1 family in rat
- Author(s)
  Osada, S., Imagawa, M., Nishihara, T.
- Journal Title
  
  DNA Sequence (in press)(印刷中)
- Data Source
  KAKENHI-PROJECT-16790053
[Presentation] ヒト凍結肝細胞を用いた短期間で毛細胆管を形成する培養法の確立2023
- Author(s)
  堺陽子, 岩尾岳洋, 松永民秀, 長田茂宏
- Organizer
  第73回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-22K06773
[Presentation] 灌流型小腸－肝臓2臓器連結デバイスを用いたヒト凍結肝細胞の長期培養法の検討2022
- Author(s)
  堺陽子, 深谷壮弥, 長田茂宏, 岩尾岳洋, 松永民秀
- Organizer
  第16回次世代を担う若手のための医療薬科学シンポジウム、口頭（O-15）
- Data Source
  KAKENHI-PROJECT-22K06773
[Presentation] ヒストン脱アセチル化酵素HDAC9スプライシングアイソフォームとハンチンチン結合因子の相互作用2022
- Author(s)
  長田茂宏, 澤田妙子, 菱田友昭, 今川正良
- Organizer
  第95年会　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07042
[Presentation] 短期間で毛細胆管を形成するヒト凍結肝細胞の培養法の確立2022
- Author(s)
  堺陽子, 深谷壮弥, 長田茂宏, 岩尾岳洋, 松永民秀
- Organizer
  第45回日本分子生物学会年会、口頭（1SP-26-13）
- Data Source
  KAKENHI-PROJECT-22K06773
[Presentation] 短期間で毛細胆管を形成するヒト凍結肝細胞の培養法の確立2022
- Author(s)
  堺陽子, 深谷壮弥, 長田茂宏, 岩尾岳洋, 松永民秀
- Organizer
  第45回日本分子生物学会年会、ポスター（IP-540）
- Data Source
  KAKENHI-PROJECT-22K06773
[Presentation] Histone deacetylase 9 interacts with huntingtin associated protein 12018
- Author(s)
  Taeko Sawada, Shinya Nakamura, Michiko Shirane, Masayoshi Imagawa, and Shigehiro Osada
- Organizer
  NCU　Global Young Investigator Forum 2018 on “Regulatory Mechanisms of Epigenetic Information and Their Clinical and Applications”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] ヒストンアセチル化酵素HBO1のオートファジーにおける役割2017
- Author(s)
  長田茂宏, 平野利忠, 西塚誠, 白根道子, 今川正良
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] オートファジー誘導過程におけるエピジェネティクス制御因子の発現変化2017
- Author(s)
  長田茂宏, 芝田裕一, 加藤苑果, 今川正良
- Organizer
  第137年会　日本薬学会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] ヒストン脱アセチル化酵素HDAC9とハンチントン病関連因子の相互作用2016
- Author(s)
  長田茂宏, 新美有希, 山口桃子, 中村真也, 今川正良
- Organizer
  第136年会　日本薬学会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] Interaction of huntingtin associated protein 1 with histone deacetylases2016
- Author(s)
  長田茂宏, 澤田妙子, 中村真也, 今川正良
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] ヒストン脱アセチル化酵素とハンチントン病関連因子HAP1の相互作用2016
- Author(s)
  澤田妙子, 中村真也, 今川正良, 長田茂宏
- Organizer
  第62回　日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] 肝化学発がん過程における腫瘍マーカー発現とエピジェネティクス制御因子2016
- Author(s)
  長田茂宏
- Organizer
  第7回名市大若手研究者ランチョンセミナー
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] アルギニンメチル化酵素CARM1スプライシングバリアントの発現2016
- Author(s)
  小島舞子, 今川正良, 長田茂宏
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2016
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] ヒストン脱アセチル化酵素HDAC9の基質および相互作用因子の探索2016
- Author(s)
  長田茂宏
- Organizer
  名市大エピジェネティクス研究会　リトリート2016
- Place of Presentation
  知多郡
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] オートファジー誘導過程におけるエピジェネティクス関連因子の発現2015
- Author(s)
  長田茂宏, 芝田裕一, 加藤苑果, 今川正良
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] ヒストン脱アセチル化酵素HDAC9が相互作用するハンチントン病関連因子HAP1の領域の解析2014
- Author(s)
  山口桃子, 市岡香貴, 今川正良, 長田茂宏
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] ヒストン脱アセチル化酵素HDAC9とハンチントン病関連タンパク質HAP1の相互作用の解析2013
- Author(s)
  新美有希, 今川正良, 長田茂宏
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2013
- Place of Presentation
  鈴鹿
- Data Source
  KAKENHI-PROJECT-23590085
[Presentation] Interaction of histone deacetylase 9 with huntingtin associated protein 1, HAP1.2013
- Author(s)
  長田茂宏, 新美有希, 山口桃子, 中村真也, 篠田晃, 林秀敏, 今川正良
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590085
[Presentation] Identification of factors interacting with histone chaperon Asf1p2011
- Author(s)
  長田茂宏
- Organizer
  第2回高次クロマチン研究会
- Place of Presentation
  蒲郡
- Year and Date
  2011-08-09
- Data Source
  KAKENHI-PROJECT-23590085
[Presentation] 肝化学発がん過程において発現上昇するヒストンメチル化酵素CARM1の機能解析2011
- Author(s)
  長田茂宏
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23590085
[Presentation] Identification of factors interacting with histone chaperon Asf1p.2011
- Author(s)
  長田茂宏
- Organizer
  第2回高次クロマチン研究会
- Place of Presentation
  蒲郡
- Data Source
  KAKENHI-PROJECT-23590085
[Presentation] Identification of factors interacting with histone chaperon Asf1p.2010
- Author(s)
  長田茂宏, 前田誠., 今川正良
- Organizer
  International Symposium on Biodiversity Sciences 2010 (ISBDS2010)
- Place of Presentation
  Nagoya
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] 化学発がん過程において発現上昇するクロマチン関連因子の解析2010
- Author(s)
  長田茂宏
- Organizer
  第130年会日本薬学会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] 化学発がん過程において発現上昇するクロマチン関連因子の解析2010
- Author(s)
  長田茂宏
- Organizer
  第130年会日本薬学会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] Identification of factors interacting with histone chaperon Asf1p.2010
- Author(s)
  Shigehiro Osada
- Organizer
  International Symposium on Biodiversity Sciences 2010
- Place of Presentation
  Nagoya
- Year and Date
  2010-08-01
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] Enhancement of anchorage-independent growth by histone deacetylase 9.2009
- Author(s)
  長田茂宏, 由良隆行, 前田誠, 橋爪博司, 今川正良
- Organizer
  21th IUBMB International Congress of Biochemistry and Molecular, Biology and 12th FAOBMB Congress
- Place of Presentation
  Shanghai, China
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] 肝前がん病変において発現上昇するヒストン脱アセチル化酵素の解析2009
- Author(s)
  長田茂宏
- Organizer
  第129年会日本薬学会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] 肝前がん病変において発現上昇するヒストン脱アセチル化酵素の解析2009
- Author(s)
  長田茂宏、由良隆行、前田誠、橋爪博司、今川正良
- Organizer
  第129年会日本薬学会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] 肝化学発がん過程において発現上昇するヒストン修飾因子の機能解析2009
- Author(s)
  長田茂宏
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] Enhancement of anchorage-independent growth by histone deacetylase 92009
- Author(s)
  長田茂宏
- Organizer
  21th IUBMB International Congress of Biochemistry and Molecular Biology and 12th FAOBMB Congress
- Place of Presentation
  Shanghai, China
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] 肝化学発がん過程において発現上昇するヒストン修飾因子の機能解析2009
- Author(s)
  長田茂宏
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20590065
[Presentation] 発がん初期に発現変化するクロマチン関連因子による転写制御2008
- Author(s)
  長田茂宏
- Organizer
  第128年会日本薬学会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590066
[Presentation] Transcriptional regulation by epigenetics modulators induced during hepatocarcinogenesis2008
- Author(s)
  Shigehiro, Osada
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590066
[Presentation] 発がん初期に発現変化するクロマチン関連因子による転写制御2008
- Author(s)
  長田茂宏
- Organizer
  第128年会日本薬学会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18590066
[Presentation] Characterization of chromatin assembly factor ASF1 that interacts with histone acetyltransferase complex2007
- Author(s)
  Shigehiro, Osada
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Toyama
- Year and Date
  2007-03-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590066
[Presentation] Identification of chromatin assembly factor Asflp-associated factors2006
- Author(s)
  Shigehiro, Osada
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590066
[Presentation] オートファジー誘導時とヒストンバリアントH2A.Zの発現
- Author(s)
  芝田裕一, 小松浩大, 今川正良, 長田茂宏
- Organizer
  第1回　名市大エピジェネティクス研究会
- Place of Presentation
  長野・南木曽
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] 肝前がん病変において発現上昇するクロマチン関連因子の解析
- Author(s)
  長田茂宏
- Organizer
  第135年会　日本薬学会
- Place of Presentation
  兵庫・神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] Characterization of coactivator-associated arginine methyltransferase 1, CARM1, induced at the early stage of hepatocarcinogenesis.
- Author(s)
  Shigehiro Osada, Yukari Funaki, Yuichi Matsuo, Masayoshi Imagawa.
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川・横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26460072
[Presentation] 化学発がん過程において発現上昇するヒストン修飾因子の解析
- Author(s)
  長田茂宏
- Organizer
  第1回　名市大エピジェネティクス研究会
- Place of Presentation
  長野・南木曽
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-26460072

1. NISHIHARA Tsutomu (50028859)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. NISHIKAWA Jun-ichi (90218131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 堺陽子 (50723079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 松永民秀 (40209581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 岩尾岳洋 (50581740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. KIKUCHI Ryoichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OSADA SHIGEHIRO 長田 茂宏

Osada Shigehiro 長田 茂宏

OSADA Shigehiro 長田 茂宏

Research Projects

Research Products

Co-Researchers

灌流型小腸-肝臓2臓器連結デバイスを用いた胆汁鬱滞肝毒性評価系の展開

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Functional elucidation and basic research for drug discovery of histone modification enzymes involved in early stages of carcinogenesisPrincipal Investigator

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Regulation of cell death by epigenetics regulatory factors upregulated during the early stages of hepatocarcinogenesisPrincipal Investigator

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Roles epigenetics regulatory factors induced hepatocarcinogenesis in malignant transformation and defense against cancer.Principal Investigator

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Analysis of the functional interactions of factors concerned with histones in malignant transformation.Principal Investigator

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Functional analysis epigenetics regulators in carcinogenesisPrincipal Investigator

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クロマチン形成因子とヒストン修飾酵素のクロストークの解明Principal Investigator

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腫瘍マーカー陽性単一細胞を用いた細胞がん化と防御の分子機構の解明Principal Investigator

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エピジェネティクス制御因子の生物学的役割の解明とがん化との関連Principal Investigator

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内分泌攪乱物質のクロマチン修飾酵素複合体に対する影響Principal Investigator

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腫瘍マーカー遺伝子の発現を負に制御する因子の解析Principal Investigator

Principal Investigator

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ダルタチオントランスフェラーゼP遺伝子の発現を負に制御する因子の解析Principal Investigator

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Acid tolerant soil bacteria which reduce nitrate to produce ammonium under facultative anaerobic condition

Principal Investigator

OSADA SHIGEHIRO 長田茂宏

Osada Shigehiro 長田茂宏

OSADA Shigehiro 長田茂宏

[Book] 第７章　がんと転写因子　「がん増殖と悪性化の分子機構」（宮澤恵二・伊東進　編）2012